LOCUS       DBERPV010000001       171231 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.01, whole genome shotgun sequence.
ACCESSION   DBERPV010000001 DBERPV010000000
VERSION     DBERPV010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 171231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 171231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..171231
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.01"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            243..899
                     /locus_tag="ACL8C7_000001"
     CDS             243..899
                     /locus_tag="ACL8C7_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HGS1394283.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            889..1212
                     /locus_tag="ACL8C7_000002"
     CDS             889..1212
                     /locus_tag="ACL8C7_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HGS1394284.1"
                     /translation="MVSKYLLLAVIFSVLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            1316..2146
                     /locus_tag="ACL8C7_000003"
     CDS             1316..2146
                     /locus_tag="ACL8C7_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS1394285.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2300..3154
                     /locus_tag="ACL8C7_000004"
     CDS             2300..3154
                     /locus_tag="ACL8C7_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HGS1394286.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEETS
                     DGLDQPVW"
     gene            3254..4627
                     /locus_tag="ACL8C7_000005"
     CDS             3254..4627
                     /locus_tag="ACL8C7_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HGS1394287.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVHEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4620..5681
                     /locus_tag="ACL8C7_000006"
     CDS             4620..5681
                     /locus_tag="ACL8C7_000006"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HGS1394288.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILTLLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSDPKQPLTQDFISTATGIDEAMAKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            5683..6375
                     /locus_tag="ACL8C7_000007"
     CDS             5683..6375
                     /locus_tag="ACL8C7_000007"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HGS1394289.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6405..6974)
                     /locus_tag="ACL8C7_000008"
     CDS             complement(6405..6974)
                     /locus_tag="ACL8C7_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HGS1394290.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIAFFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPTPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            7109..7723
                     /locus_tag="ACL8C7_000009"
     CDS             7109..7723
                     /locus_tag="ACL8C7_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HGS1394291.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7701..9371
                     /locus_tag="ACL8C7_000010"
     CDS             7701..9371
                     /locus_tag="ACL8C7_000010"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGS1394292.1"
                     /translation="MKNWRQNRMKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSR
                     EKEAQRVAQRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQ
                     LERKASPYISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDF
                     KPAGNSFAIPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIF
                     HIGETVDRESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLT
                     LRQTFANYQKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNI
                     HDIYQLELSQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLR
                     NNISDERETLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVE
                     NYFAHGVDHRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQ
                     ASYSDQRKSIGIINVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9383..10669
                     /locus_tag="ACL8C7_000011"
     CDS             9383..10669
                     /locus_tag="ACL8C7_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGS1394293.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLTSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10721..11254
                     /locus_tag="ACL8C7_000012"
     CDS             10721..11254
                     /locus_tag="ACL8C7_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1394294.1"
                     /translation="MKKKPIYLWILLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            11332..11802
                     /gene="nrdI"
                     /locus_tag="ACL8C7_000013"
     CDS             11332..11802
                     /gene="nrdI"
                     /locus_tag="ACL8C7_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HGS1394295.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(12095..13357)
                     /locus_tag="ACL8C7_000014"
     CDS             complement(12095..13357)
                     /locus_tag="ACL8C7_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NRAMP family divalent metal transporter"
                     /protein_id="HGS1394296.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(13667..14125)
                     /locus_tag="ACL8C7_000015"
     CDS             complement(13667..14125)
                     /locus_tag="ACL8C7_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HGS1394297.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(14122..14562)
                     /locus_tag="ACL8C7_000016"
     CDS             complement(14122..14562)
                     /locus_tag="ACL8C7_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGS1394298.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            14918..16867
                     /gene="mutL"
                     /locus_tag="ACL8C7_000017"
     CDS             14918..16867
                     /gene="mutL"
                     /locus_tag="ACL8C7_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HGS1394299.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(17192..17659)
                     /gene="ribE"
                     /locus_tag="ACL8C7_000018"
     CDS             complement(17192..17659)
                     /gene="ribE"
                     /locus_tag="ACL8C7_000018"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009349 - riboflavin synthase complex
                     [Evidence IEA];
                     GO_function: GO:0000906 - 6,7-dimethyl-8-ribityllumazine
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HGS1394300.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(17660..18865)
                     /locus_tag="ACL8C7_000019"
     CDS             complement(17660..18865)
                     /locus_tag="ACL8C7_000019"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA];
                     GO_function: GO:0008686 -
                     3,4-dihydroxy-2-butanone-4-phosphate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HGS1394301.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERSGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(18885..19520)
                     /gene="ribE"
                     /locus_tag="ACL8C7_000020"
     CDS             complement(18885..19520)
                     /gene="ribE"
                     /locus_tag="ACL8C7_000020"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004746 - riboflavin synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HGS1394302.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(19505..20605)
                     /gene="ribD"
                     /locus_tag="ACL8C7_000021"
     CDS             complement(19505..20605)
                     /gene="ribD"
                     /locus_tag="ACL8C7_000021"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA];
                     GO_function: GO:0008835 -
                     diaminohydroxyphosphoribosylaminopyrimidine deaminase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HGS1394303.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVQQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(20739..20853)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            21010..21603
                     /gene="ruvA"
                     /locus_tag="ACL8C7_000022"
     CDS             21010..21603
                     /gene="ruvA"
                     /locus_tag="ACL8C7_000022"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HGS1394304.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            21613..22176
                     /locus_tag="ACL8C7_000023"
     CDS             21613..22176
                     /locus_tag="ACL8C7_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HGS1394305.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQVLFELLCMETYQA
                     GLSWETVLNKRQAFREVFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKLFATRANAQ
                     VFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFIG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            22173..22850
                     /locus_tag="ACL8C7_000024"
     CDS             22173..22850
                     /locus_tag="ACL8C7_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGS1394306.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSVIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVRL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(23005..24036)
                     /locus_tag="ACL8C7_000025"
     CDS             complement(23005..24036)
                     /locus_tag="ACL8C7_000025"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="HGS1394307.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCPKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(24291..24974)
                     /locus_tag="ACL8C7_000026"
     CDS             complement(24291..24974)
                     /locus_tag="ACL8C7_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HGS1394308.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(24986..25930)
                     /locus_tag="ACL8C7_000027"
     CDS             complement(24986..25930)
                     /locus_tag="ACL8C7_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGS1394309.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            26062..28893
                     /gene="uvrA"
                     /locus_tag="ACL8C7_000028"
     CDS             26062..28893
                     /gene="uvrA"
                     /locus_tag="ACL8C7_000028"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HGS1394310.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            28886..29947
                     /locus_tag="ACL8C7_000029"
     CDS             28886..29947
                     /locus_tag="ACL8C7_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGS1394311.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLDLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            30079..30477
                     /gene="spx"
                     /locus_tag="ACL8C7_000030"
     CDS             30079..30477
                     /gene="spx"
                     /locus_tag="ACL8C7_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HGS1394312.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            30543..31112
                     /locus_tag="ACL8C7_000031"
     CDS             30543..31112
                     /locus_tag="ACL8C7_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP0191 family lipoprotein"
                     /protein_id="HGS1394313.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSNYISDRLANGATEQ"
     gene            31199..31465
                     /locus_tag="ACL8C7_000032"
     CDS             31199..31465
                     /locus_tag="ACL8C7_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HGS1394314.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            31469..31888
                     /gene="ruvX"
                     /locus_tag="ACL8C7_000033"
     CDS             31469..31888
                     /gene="ruvX"
                     /locus_tag="ACL8C7_000033"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003090938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HGS1394315.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            31904..32209
                     /locus_tag="ACL8C7_000034"
     CDS             31904..32209
                     /locus_tag="ACL8C7_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HGS1394316.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            32468..33718
                     /locus_tag="ACL8C7_000035"
     CDS             32468..33718
                     /locus_tag="ACL8C7_000035"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HGS1394317.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLHPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDERDVTGYDIVSSYREFISDFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            33802..34254
                     /locus_tag="ACL8C7_000036"
     CDS             33802..34254
                     /locus_tag="ACL8C7_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0198 family lipoprotein"
                     /protein_id="HGS1394318.1"
                     /translation="MKLKRFTLSLASLASFSLLVACSQRAQQVQQPAQQVQQPAQQNT
                     NTANAGGNQNQAAPVQNQPVAQPTDIDGTYTGQDDGDRITLVVTGTTGTWTELESDGD
                     QKVKQVTFDSANQRMIIGDDVKIYTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            34400..35932
                     /gene="cls"
                     /locus_tag="ACL8C7_000037"
     CDS             34400..35932
                     /gene="cls"
                     /locus_tag="ACL8C7_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HGS1394319.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            36010..36153
                     /locus_tag="ACL8C7_000038"
     CDS             36010..36153
                     /locus_tag="ACL8C7_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394320.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            36190..37728
                     /locus_tag="ACL8C7_000039"
     CDS             36190..37728
                     /locus_tag="ACL8C7_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HGS1394321.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFVHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            37848..40055
                     /gene="nrdD"
                     /locus_tag="ACL8C7_000040"
     CDS             37848..40055
                     /gene="nrdD"
                     /locus_tag="ACL8C7_000040"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HGS1394322.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKQEDYAWK
                     KAQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            40067..40207
                     /locus_tag="ACL8C7_000041"
     CDS             40067..40207
                     /locus_tag="ACL8C7_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394323.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            40251..40757
                     /locus_tag="ACL8C7_000042"
     CDS             40251..40757
                     /locus_tag="ACL8C7_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1394324.1"
                     /translation="MELRRPRLADKETVLEMMTEFEKFQSPHDGGFWNTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVVFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANDGIFEDARNGVER
                     YWIEVANE"
     gene            40750..41340
                     /gene="nrdG"
                     /locus_tag="ACL8C7_000043"
     CDS             40750..41340
                     /gene="nrdG"
                     /locus_tag="ACL8C7_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HGS1394325.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVAGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            41337..41954
                     /locus_tag="ACL8C7_000044"
     CDS             41337..41954
                     /locus_tag="ACL8C7_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HGS1394326.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            42220..42528
                     /gene="rpsJ"
                     /locus_tag="ACL8C7_000045"
     CDS             42220..42528
                     /gene="rpsJ"
                     /locus_tag="ACL8C7_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HGS1394327.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            42744..43370
                     /gene="rplC"
                     /locus_tag="ACL8C7_000046"
     CDS             42744..43370
                     /gene="rplC"
                     /locus_tag="ACL8C7_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HGS1394328.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            43395..44018
                     /gene="rplD"
                     /locus_tag="ACL8C7_000047"
     CDS             43395..44018
                     /gene="rplD"
                     /locus_tag="ACL8C7_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HGS1394329.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            44018..44314
                     /locus_tag="ACL8C7_000048"
     CDS             44018..44314
                     /locus_tag="ACL8C7_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HGS1394330.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            44332..45165
                     /gene="rplB"
                     /locus_tag="ACL8C7_000049"
     CDS             44332..45165
                     /gene="rplB"
                     /locus_tag="ACL8C7_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HGS1394331.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            45269..45550
                     /gene="rpsS"
                     /locus_tag="ACL8C7_000050"
     CDS             45269..45550
                     /gene="rpsS"
                     /locus_tag="ACL8C7_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HGS1394332.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            45562..45906
                     /gene="rplV"
                     /locus_tag="ACL8C7_000051"
     CDS             45562..45906
                     /gene="rplV"
                     /locus_tag="ACL8C7_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HGS1394333.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            45919..46572
                     /gene="rpsC"
                     /locus_tag="ACL8C7_000052"
     CDS             45919..46572
                     /gene="rpsC"
                     /locus_tag="ACL8C7_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HGS1394334.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            46576..46989
                     /gene="rplP"
                     /locus_tag="ACL8C7_000053"
     CDS             46576..46989
                     /gene="rplP"
                     /locus_tag="ACL8C7_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HGS1394335.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            46999..47205
                     /gene="rpmC"
                     /locus_tag="ACL8C7_000054"
     CDS             46999..47205
                     /gene="rpmC"
                     /locus_tag="ACL8C7_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HGS1394336.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            47230..47490
                     /gene="rpsQ"
                     /locus_tag="ACL8C7_000055"
     CDS             47230..47490
                     /gene="rpsQ"
                     /locus_tag="ACL8C7_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HGS1394337.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            47516..47884
                     /gene="rplN"
                     /locus_tag="ACL8C7_000056"
     CDS             47516..47884
                     /gene="rplN"
                     /locus_tag="ACL8C7_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HGS1394338.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            47962..48267
                     /gene="rplX"
                     /locus_tag="ACL8C7_000057"
     CDS             47962..48267
                     /gene="rplX"
                     /locus_tag="ACL8C7_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HGS1394339.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            48291..48833
                     /gene="rplE"
                     /locus_tag="ACL8C7_000058"
     CDS             48291..48833
                     /gene="rplE"
                     /locus_tag="ACL8C7_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HGS1394340.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            48851..49120
                     /gene="rpsN"
                     /locus_tag="ACL8C7_000059"
     CDS             48851..49120
                     /gene="rpsN"
                     /locus_tag="ACL8C7_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HGS1394341.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            49405..49803
                     /gene="rpsH"
                     /locus_tag="ACL8C7_000060"
     CDS             49405..49803
                     /gene="rpsH"
                     /locus_tag="ACL8C7_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HGS1394342.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            49995..50531
                     /gene="rplF"
                     /locus_tag="ACL8C7_000061"
     CDS             49995..50531
                     /gene="rplF"
                     /locus_tag="ACL8C7_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HGS1394343.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            50615..50971
                     /gene="rplR"
                     /locus_tag="ACL8C7_000062"
     CDS             50615..50971
                     /gene="rplR"
                     /locus_tag="ACL8C7_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HGS1394344.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            50989..51483
                     /gene="rpsE"
                     /locus_tag="ACL8C7_000063"
     CDS             50989..51483
                     /gene="rpsE"
                     /locus_tag="ACL8C7_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HGS1394345.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            51497..51679
                     /gene="rpmD"
                     /locus_tag="ACL8C7_000064"
     CDS             51497..51679
                     /gene="rpmD"
                     /locus_tag="ACL8C7_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HGS1394346.1"
                     /translation="MAQIKITLTKSPIGRIPSQRKTVVALGLGKLNSSVIKEDNAAIR
                     GMITAVSHLVTVEEVN"
     gene            51824..52264
                     /gene="rplO"
                     /locus_tag="ACL8C7_000065"
     CDS             51824..52264
                     /gene="rplO"
                     /locus_tag="ACL8C7_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HGS1394347.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            52277..53587
                     /gene="secY"
                     /locus_tag="ACL8C7_000066"
     CDS             52277..53587
                     /gene="secY"
                     /locus_tag="ACL8C7_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HGS1394348.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            53738..54376
                     /locus_tag="ACL8C7_000067"
     CDS             53738..54376
                     /locus_tag="ACL8C7_000067"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HGS1394349.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            54493..54711
                     /gene="infA"
                     /locus_tag="ACL8C7_000068"
     CDS             54493..54711
                     /gene="infA"
                     /locus_tag="ACL8C7_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HGS1394350.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            54736..54852
                     /gene="rpmJ"
                     /locus_tag="ACL8C7_000069"
     CDS             54736..54852
                     /gene="rpmJ"
                     /locus_tag="ACL8C7_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HGS1394351.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            54870..55235
                     /gene="rpsM"
                     /locus_tag="ACL8C7_000070"
     CDS             54870..55235
                     /gene="rpsM"
                     /locus_tag="ACL8C7_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HGS1394352.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            55253..55636
                     /gene="rpsK"
                     /locus_tag="ACL8C7_000071"
     CDS             55253..55636
                     /gene="rpsK"
                     /locus_tag="ACL8C7_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HGS1394353.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            55679..56614
                     /locus_tag="ACL8C7_000072"
     CDS             55679..56614
                     /locus_tag="ACL8C7_000072"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HGS1394354.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            56626..57012
                     /gene="rplQ"
                     /locus_tag="ACL8C7_000073"
     CDS             56626..57012
                     /gene="rplQ"
                     /locus_tag="ACL8C7_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HGS1394355.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            57277..57543
                     /locus_tag="ACL8C7_000074"
     CDS             57277..57543
                     /locus_tag="ACL8C7_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HGS1394356.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            57553..58890
                     /locus_tag="ACL8C7_000075"
     CDS             57553..58890
                     /locus_tag="ACL8C7_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HGS1394357.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            59134..59826
                     /locus_tag="ACL8C7_000076"
     CDS             59134..59826
                     /locus_tag="ACL8C7_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGS1394358.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEIIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(59929..61564)
                     /locus_tag="ACL8C7_000077"
                     /pseudo
     CDS             complement(59929..61564)
                     /locus_tag="ACL8C7_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(61554..62645)
                     /locus_tag="ACL8C7_000078"
                     /pseudo
     CDS             complement(61554..62645)
                     /locus_tag="ACL8C7_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289362.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(62658..63779)
                     /locus_tag="ACL8C7_000079"
                     /pseudo
     CDS             complement(62658..63779)
                     /locus_tag="ACL8C7_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085230.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(63996..64220)
                     /locus_tag="ACL8C7_000080"
                     /pseudo
     CDS             complement(63996..64220)
                     /locus_tag="ACL8C7_000080"
                     /inference="COORDINATES: protein motif:HMM:NF024242.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(64268..65044)
                     /locus_tag="ACL8C7_000081"
     CDS             complement(64268..65044)
                     /locus_tag="ACL8C7_000081"
                     /EC_number="1.97.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0043687 - post-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HGS1394359.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            65166..65912
                     /locus_tag="ACL8C7_000082"
     CDS             65166..65912
                     /locus_tag="ACL8C7_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGS1394360.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            65925..66905
                     /locus_tag="ACL8C7_000083"
     CDS             65925..66905
                     /locus_tag="ACL8C7_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HGS1394361.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            67100..67420
                     /locus_tag="ACL8C7_000084"
     CDS             67100..67420
                     /locus_tag="ACL8C7_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGS1394362.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            67466..67774
                     /locus_tag="ACL8C7_000085"
     CDS             67466..67774
                     /locus_tag="ACL8C7_000085"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS1394363.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            67791..69089
                     /locus_tag="ACL8C7_000086"
     CDS             67791..69089
                     /locus_tag="ACL8C7_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGS1394364.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            69240..71678
                     /locus_tag="ACL8C7_000087"
     CDS             69240..71678
                     /locus_tag="ACL8C7_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HGS1394365.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            71697..72365
                     /locus_tag="ACL8C7_000088"
     CDS             71697..72365
                     /locus_tag="ACL8C7_000088"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HGS1394366.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            72383..73471
                     /locus_tag="ACL8C7_000089"
     CDS             72383..73471
                     /locus_tag="ACL8C7_000089"
                     /EC_number="1.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008888 - glycerol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HGS1394367.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNCPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKSVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            73926..76427
                     /gene="leuS"
                     /locus_tag="ACL8C7_000090"
     CDS             73926..76427
                     /gene="leuS"
                     /locus_tag="ACL8C7_000090"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HGS1394368.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKSKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK"
     gene            76566..77408
                     /locus_tag="ACL8C7_000091"
     CDS             76566..77408
                     /locus_tag="ACL8C7_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394369.1"
                     /translation="MNRLVNDSRKCEILLFKISIIVVSVIVLVMSIVGAYYFKNCLWD
                     KESLNLTLTLDTLFAVFITFFSFSNDKSSNIFGISPNEIIRTQSEVYQFLFTKSFATL
                     LIVTNLLSIIHYFGAKNLIVSFNETYPRIQSSVGIMWLPLFGILIIYFIWLLIEGLKY
                     IRKINYIIQNREIIYFYSQVKVVDKLTDSESKKYGEYIDLYESCRQNNLSVLLNFLQN
                     SDDKRGVIASNSVRIMFESLDKADQIAALNICRNYVARENVLNKEDAEKLLNEIDKKL
                     EISR"
     gene            77464..78159
                     /locus_tag="ACL8C7_000092"
     CDS             77464..78159
                     /locus_tag="ACL8C7_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGS1394370.1"
                     /translation="MPVNEYGQMIGESMEGYTPGALPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPREMWTYLFQEPVADMGELVSLLNQMLARKDRFYYAIIDKATGKALG
                     TFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYIFEELNYRRYEWKCDAL
                     NLPSRRVAERLGFVYEGTFRQAVVYKGRTRDTDWLSMIDMDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            78171..78587
                     /locus_tag="ACL8C7_000093"
     CDS             78171..78587
                     /locus_tag="ACL8C7_000093"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1394371.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEHALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVFVQDLIVLPIYQRQGIGSALMKEALKDYKDAYQVQ
                     LVTEETEKNVGFYRSMGFEILSTYNCIGMTWANREK"
     gene            complement(79420..79494)
                     /locus_tag="ACL8C7_000094"
     CDS             complement(79420..79494)
                     /locus_tag="ACL8C7_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HGS1394372.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDK"
     gene            79628..80626
                     /gene="ruvB"
                     /locus_tag="ACL8C7_000095"
     CDS             79628..80626
                     /gene="ruvB"
                     /locus_tag="ACL8C7_000095"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HGS1394373.1"
                     /translation="MSRILDNEIMGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEA
                     AKMRDEALDHVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELE
                     PGDVLFIDEIHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPR
                     IANRLLKRVRDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGG
                     PVGLGTLSVNIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            80607..81179
                     /locus_tag="ACL8C7_000096"
     CDS             80607..81179
                     /locus_tag="ACL8C7_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HGS1394374.1"
                     /translation="MNTVKNKQEILEAFRESPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTAVGLRLNEESDFELYVPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            81410..82168
                     /locus_tag="ACL8C7_000097"
     CDS             81410..82168
                     /locus_tag="ACL8C7_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HGS1394375.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            82177..82980
                     /locus_tag="ACL8C7_000098"
     CDS             82177..82980
                     /locus_tag="ACL8C7_000098"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004605 - phosphatidate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0016024 - CDP-diacylglycerol biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HGS1394376.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            83002..84261
                     /gene="rseP"
                     /locus_tag="ACL8C7_000099"
     CDS             83002..84261
                     /gene="rseP"
                     /locus_tag="ACL8C7_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HGS1394377.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETSQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            84274..86127
                     /locus_tag="ACL8C7_000100"
     CDS             84274..86127
                     /locus_tag="ACL8C7_000100"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HGS1394378.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            86226..87605
                     /gene="bglA"
                     /locus_tag="ACL8C7_000101"
     CDS             86226..87605
                     /gene="bglA"
                     /locus_tag="ACL8C7_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HGS1394379.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNTQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KKLSDNNGF"
     gene            87797..89605
                     /gene="glmS"
                     /locus_tag="ACL8C7_000102"
     CDS             87797..89605
                     /gene="glmS"
                     /locus_tag="ACL8C7_000102"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HGS1394380.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTDGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQVFDLVHELSIVAQSIESTLSEKET
                     IEVKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLSLLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTEDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            89877..90926
                     /locus_tag="ACL8C7_000103"
     CDS             89877..90926
                     /locus_tag="ACL8C7_000103"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HGS1394381.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(91026..94868)
                     /gene="spuA"
                     /locus_tag="ACL8C7_000104"
     CDS             complement(91026..94868)
                     /gene="spuA"
                     /locus_tag="ACL8C7_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HGS1394382.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPAASPA
                     DPAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDD
                     VEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVE
                     KLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQW
                     PDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQ
                     IFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHL
                     GNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGK
                     LGADLKEEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDST
                     NKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDP
                     AKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDY
                     LKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSD
                     PKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPR
                     TSFGGGRLGTTHHMTKRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARAL
                     NPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPA
                     FITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKA
                     ENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHL
                     LRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQS
                     TDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKARE
                     FNLGTAFAHLRNAEVLADENQAGPVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTS
                     HESTAAEKPDSTPSKPEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENKPSQATAD
                     SQAEQPAQEAQASSVKEAVQNESVENSSKKNIPATPDRQAELPNTGIKNENKLLFAGI
                     SLLALLGLGFLLKNKKEN"
     gene            95285..95698
                     /gene="rpsL"
                     /locus_tag="ACL8C7_000105"
     CDS             95285..95698
                     /gene="rpsL"
                     /locus_tag="ACL8C7_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HGS1394383.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            95718..96188
                     /gene="rpsG"
                     /locus_tag="ACL8C7_000106"
     CDS             95718..96188
                     /gene="rpsG"
                     /locus_tag="ACL8C7_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HGS1394384.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            96613..98694
                     /gene="fusA"
                     /locus_tag="ACL8C7_000107"
     CDS             96613..98694
                     /gene="fusA"
                     /locus_tag="ACL8C7_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HGS1394385.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEEIRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            98798..103189
                     /locus_tag="ACL8C7_000108"
     CDS             98798..103189
                     /locus_tag="ACL8C7_000108"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HGS1394386.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMTPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLDRLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNEIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNDYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYCSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            103291..103554
                     /locus_tag="ACL8C7_000109"
     CDS             103291..103554
                     /locus_tag="ACL8C7_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HGS1394387.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQVLTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            103547..103825
                     /locus_tag="ACL8C7_000110"
     CDS             103547..103825
                     /locus_tag="ACL8C7_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HGS1394388.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            103846..103998
                     /locus_tag="ACL8C7_000111"
     CDS             103846..103998
                     /locus_tag="ACL8C7_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394389.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGLF
                     SALKEK"
     gene            104020..105261
                     /locus_tag="ACL8C7_000112"
     CDS             104020..105261
                     /locus_tag="ACL8C7_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HGS1394390.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFFHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDLLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEGFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVIFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            105271..105501
                     /locus_tag="ACL8C7_000113"
     CDS             105271..105501
                     /locus_tag="ACL8C7_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGS1394391.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAVLGAMIVLAIFWRRGS"
     gene            105712..106434
                     /locus_tag="ACL8C7_000114"
     CDS             105712..106434
                     /locus_tag="ACL8C7_000114"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGS1394392.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            106652..107986
                     /gene="pepC"
                     /locus_tag="ACL8C7_000115"
     CDS             106652..107986
                     /gene="pepC"
                     /locus_tag="ACL8C7_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HGS1394393.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALECRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(108042..108953)
                     /locus_tag="ACL8C7_000116"
     CDS             complement(108042..108953)
                     /locus_tag="ACL8C7_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGS1394394.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(108977..109780)
                     /locus_tag="ACL8C7_000117"
     CDS             complement(108977..109780)
                     /locus_tag="ACL8C7_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HGS1394395.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(109808..110797)
                     /locus_tag="ACL8C7_000118"
     CDS             complement(109808..110797)
                     /locus_tag="ACL8C7_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS1394396.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(111031..112050)
                     /gene="adhP"
                     /locus_tag="ACL8C7_000119"
     CDS             complement(111031..112050)
                     /gene="adhP"
                     /locus_tag="ACL8C7_000119"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HGS1394397.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSVRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVAPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(112389..113201)
                     /locus_tag="ACL8C7_000120"
     CDS             complement(112389..113201)
                     /locus_tag="ACL8C7_000120"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGS1394398.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEVFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            113391..114812
                     /locus_tag="ACL8C7_000121"
     CDS             113391..114812
                     /locus_tag="ACL8C7_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HGS1394399.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNNHVGAAFEDLKTIFGAALGSEGLGALVSDTARL
                     PETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVG
                     AIAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILI
                     IVGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQV
                     KDVHAMIWILDALFILNYISMAL"
     gene            114865..115572
                     /locus_tag="ACL8C7_000122"
     CDS             114865..115572
                     /locus_tag="ACL8C7_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGS1394400.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGLVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            115667..116641
                     /gene="folP"
                     /locus_tag="ACL8C7_000123"
     CDS             115667..116641
                     /gene="folP"
                     /locus_tag="ACL8C7_000123"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HGS1394401.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGKFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGADLVNDITGLMGDEKMAHVVAEARAQVVIMFNPVMARPQHPSSLI
                     FPHFGFGQAFTEEELADFETLPIEELMEAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            116643..117965
                     /locus_tag="ACL8C7_000124"
     CDS             116643..117965
                     /locus_tag="ACL8C7_000124"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HGS1394402.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNVTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            117946..118500
                     /gene="folE"
                     /locus_tag="ACL8C7_000125"
     CDS             117946..118500
                     /gene="folE"
                     /locus_tag="ACL8C7_000125"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA];
                     GO_process: GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HGS1394403.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            118543..119355
                     /gene="folK"
                     /locus_tag="ACL8C7_000126"
     CDS             118543..119355
                     /gene="folK"
                     /locus_tag="ACL8C7_000126"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003848 -
                     2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HGS1394404.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIEKMRNRGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(119506..119823)
                     /locus_tag="ACL8C7_000127"
     CDS             complement(119506..119823)
                     /locus_tag="ACL8C7_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HGS1394405.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            120180..120626
                     /gene="rplM"
                     /locus_tag="ACL8C7_000128"
     CDS             120180..120626
                     /gene="rplM"
                     /locus_tag="ACL8C7_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HGS1394406.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISELI"
     gene            120645..121037
                     /gene="rpsI"
                     /locus_tag="ACL8C7_000129"
     CDS             120645..121037
                     /gene="rpsI"
                     /locus_tag="ACL8C7_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HGS1394407.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(121145..122365)
                     /locus_tag="ACL8C7_000130"
     CDS             complement(121145..122365)
                     /locus_tag="ACL8C7_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014619928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGS1394408.1"
                     /translation="MTVTKTNSNTYNLKVYIPKEIRPKMGIKGNHFVKRYKTRKEAKE
                     AELEILTKIHQLENGEDILLSKTNDILFSEFFNNIWWDSYKAGQTTSTTKPPTQVTID
                     NTKTVFRKHILPMFGNYSINFLNQNKQVVLNLMTAKAEEYANFKVIRSYVNSIFDWAE
                     ELEYIESNRLSKTIKRIKATKKLKLQDSKNEEDLYLSSEELQDWFDAFREDLENDKLS
                     LKDYVLFFTTFILSDRKSESYALHWKNIDLANAQIDLRHALDKYKNVKSTKGNKKTIF
                     SIPSYLVSLLSEWKKQQKYELAKFGIMQTSDQLVFTYIDTKGNVNSPLHVDYLNNKMN
                     SVKRRHPKLKHATPHKLRHTGATLAKKAGMSLEAISEALTHSDTITTKTYVNASNIVP
                     LSAGQVAYQHLKNK"
     gene            complement(122407..122676)
                     /locus_tag="ACL8C7_000131"
     CDS             complement(122407..122676)
                     /locus_tag="ACL8C7_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS1394409.1"
                     /translation="MQVILPTEQVQEIQSMITNLLQNEISHFKEDLGLDSPYLNKGQT
                     CKYLGISNNTLDGWIQKGLPVIKIGKTVRFNKNEIDKWLCRKAML"
     gene            complement(122684..123478)
                     /locus_tag="ACL8C7_000132"
     CDS             complement(122684..123478)
                     /locus_tag="ACL8C7_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HGS1394410.1"
                     /translation="MSYNRKIIRTSSYLEIWEYESPIFSNDTTQIDEEHISLKEKKKR
                     RTFEELTTAEQDERIKRISNTRKNSKWKLQRLIDTNFDDRTSFLTLTTKENIQNRYEF
                     NLLFDKFIKRLNYHIYHSKKRLIKYIAVLERQKRGAWHAHILLFSFPFIPHKELLTIW
                     GLGAVRINKLNKLDDSSNAGRYVAKYMEKGIGQELLESLGKKAFYSSRNLQKPEEIKL
                     FTSESLDNLVKNEDILYESNYISKVFRKGHLIDNKVKYKKIKLSKE"
     gene            complement(123650..124423)
                     /locus_tag="ACL8C7_000133"
     CDS             complement(123650..124423)
                     /locus_tag="ACL8C7_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGS1394411.1"
                     /translation="MKTLLIGDLHLKSQLILPIIDKIIQTHNIKRVIFLGDYVDLHGQ
                     TNNIQLYAKDLTFLYSWKIDKEQNGIEVINLIGNHDAYYLLGDQAPFSIQNLEVFFAV
                     QGLLQDLKLQVAYQLDDYLVSHAGFNQIFDPQKWHFFPYTKEHEEELDILAYTIGPMR
                     GGEALGGSPLWAHFRELELLPNQDFPKQIVGHTPKESIDISKNIIGIDTFSLYIDKDN
                     KYQFIGNGDLLVYDQGHLEIISTDWATDQTLKQLPKPQI"
     gene            complement(124498..125226)
                     /locus_tag="ACL8C7_000134"
     CDS             complement(124498..125226)
                     /locus_tag="ACL8C7_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGS1394412.1"
                     /translation="MAKLFAISDIHGHLDEFISALSKVDLSDKNNRLILIGDYIDNGL
                     QSFQVISKIIKLEEIYPNQIITLLGNHEEWFYDWLILDKPTASAFPETIKSFFSPEEL
                     NYIFKSNANNFETGVRNEIKNNIKFNPFINWFKKRYKDKRYYETDTQIFVHAGIDEEA
                     GMLWKELTSSKIFTNKFPITTGRFHKAIISGHIASWEVAKDKTYQGKIYFDGKNHYFI
                     DGDVYHSKTIPVICYDTVTKSYQY"
     gene            complement(125243..125557)
                     /locus_tag="ACL8C7_000135"
     CDS             complement(125243..125557)
                     /locus_tag="ACL8C7_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394413.1"
                     /translation="MKINDFLKPELLGNKFVAVKGYTEVLDRETNKPVALRLNVSIQD
                     EDSDFFMEMIQIKVNTLSPTATPQLLSDKKTCPVKLSNLTVGQFNGNLWFSCNDVVPI
                     SK"
     gene            complement(125653..126972)
                     /locus_tag="ACL8C7_000136"
     CDS             complement(125653..126972)
                     /locus_tag="ACL8C7_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HGS1394414.1"
                     /translation="MFKLKKEANLKRNYFITSSRLKLLHLIIITFSILVLLGLIVSIR
                     APAFIQILCIVFGILAIYKINNKLKDFRYELDFDLIIRESLLLVLYTNHLYTSEKDNS
                     GYEEIIRSAILKYELDNQNSRIIIKALIRGDEFSKKVQTLDDVLAGVLELELEEKITH
                     PNIVEYHFYYKKPDRLILSPHNHKKEIDSLDIDLGYDITYNPIKCPHILVSGGTGSGK
                     SIFISFLIIELLKRNSTLYIADPKNSDLGSLSHYLSDKYIATTPNNIARIVRLVVEQM
                     QERYQAMRDNFHYGSNFADHGFKPVWLIFDEMGAFQASATDKKSKEVITEAMDGIKQI
                     ILLGRQAGVFILISAQQMRAETLNTDLRDNLGLRIALGANSIEGYRMVFGTATPDKFK
                     SIEEKGAGYLYMQGSGKEKAQYWESPYLDTTQFDFIKELQLYVTKSK"
     gene            complement(127045..127515)
                     /locus_tag="ACL8C7_000137"
     CDS             complement(127045..127515)
                     /locus_tag="ACL8C7_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394415.1"
                     /translation="MVRVYKSVRLAYEAKVWIDELIQKKERKIKELNQDNFLNTLEQT
                     LLSNHYDELNGVSFNIVLKASIGSIIEEAYRNTKYYSIAKWQNLRQKMEKDIKTVNPS
                     LETSVTPRLYLDENVLNGLDEFRYHLMKEDGATRLPRLSYIIKLVVYSYWKTQQ"
     gene            complement(127528..128190)
                     /locus_tag="ACL8C7_000138"
     CDS             complement(127528..128190)
                     /locus_tag="ACL8C7_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001834110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394416.1"
                     /translation="MGWQESQDSIIRGETINSYLTTFKKAMELSYNYNFLYNELKLDE
                     IKTIGKKDFPQYYINLYKNKNYEKFDIIAKNADNFKKFAELTHTIGNFIVLPHWMNTG
                     RYNFSKDYWDLTLLSLYEWFNAFLTEDESWKKFIKNYYLQPYVNSNYQPEIFWENHSF
                     RNKELEGTEEFSIFLKKVNERIEERGKFIIKQICDKLDQKDFNFYKEIKNMETIRFSN
                     EF"
     gene            complement(128195..128422)
                     /locus_tag="ACL8C7_000139"
     CDS             complement(128195..128422)
                     /locus_tag="ACL8C7_000139"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394417.1"
                     /translation="MEHQEVIDWLKYCDENNIKPWEWDFKNCYSDTLTPDSITNFLKY
                     KNAELTNPTTFRVTKLIGKYADSDKEAFYTI"
     gene            complement(128496..128891)
                     /locus_tag="ACL8C7_000140"
     CDS             complement(128496..128891)
                     /locus_tag="ACL8C7_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000409324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394418.1"
                     /translation="MEIYTYSDFLQEKTALTFEDAHKIYNELISSFDIKDPIFLDDWT
                     MLIELASEYTEIRVKSATVSKERQDKHGTLRTSAHDAFMVQLNALKNEIESTGGNTSW
                     FDKITDDRQRQGDFANYLAYIYAVSTRSS"
     gene            complement(129337..129849)
                     /locus_tag="ACL8C7_000141"
     CDS             complement(129337..129849)
                     /locus_tag="ACL8C7_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394419.1"
                     /translation="MEFQVRVSSEAIFYFEKLKKMYSNNSKFELTRSQILTRAFEETK
                     IITNWTSIINDTETISLEYLEYQKGYGTNVKVQISDEVEKGIRELKILLPNFTTTRSV
                     TIGVAVKFMLKGAIILNKTGKINTNKNLSTMEAIEELKQNLQDIVAPINYNVLENIMD
                     NFKNNISLIQ"
     gene            complement(130118..130531)
                     /locus_tag="ACL8C7_000142"
     CDS             complement(130118..130531)
                     /locus_tag="ACL8C7_000142"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394420.1"
                     /translation="MTSILFSNSPNVLVYQIHKEKVIAKNITLDYSNSDFIFPVIDTY
                     IDSGNGFDYIFSHDVLVIPDPRSKQSIKTYSLYFNSDMIPISTQGEWIACFGIIKKEN
                     DMIVAGNIQLDQTLHLIKHFTITDSNNNRLPIQYT"
     gene            complement(130597..131310)
                     /locus_tag="ACL8C7_000143"
     CDS             complement(130597..131310)
                     /locus_tag="ACL8C7_000143"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGS1394421.1"
                     /translation="MKILNININDFGGPENHREDFKNKFGNGKYIQEWDKLDKKETIN
                     SFISKIDEYKPDIIIIQEYDINSKECREIFEPLMVEKGYIPKSVPVKSKKRPSMTVFF
                     VKNGLGDEDISTGHDRNARAYAIQVNDLVIYGTHVPPSRDVVSFWKEINNFVQKFKNN
                     KLLLIGDFNTVNFKNNKALDNLLENPIHKIHKIWSHEGCNIPGDYVLANFDINQDGID
                     YFATKTITDHEFGVIITTD"
     gene            132183..132392
                     /locus_tag="ACL8C7_000144"
                     /pseudo
     CDS             132183..132392
                     /locus_tag="ACL8C7_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            132547..132885
                     /locus_tag="ACL8C7_000145"
     CDS             132547..132885
                     /locus_tag="ACL8C7_000145"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="HGS1394422.1"
                     /translation="MTLTIHVYYKGDGDSAIKFAREMLDSGLVEEIRNQKGNLKYEYF
                     LPIEKEGTILLIDQWINQETLDKHYQSKTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            133075..134511
                     /locus_tag="ACL8C7_000146"
     CDS             133075..134511
                     /locus_tag="ACL8C7_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HGS1394423.1"
                     /translation="MTTFKDGFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITLGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPVTCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKEVISSNGESVE"
     gene            134563..134802
                     /locus_tag="ACL8C7_000147"
     CDS             134563..134802
                     /locus_tag="ACL8C7_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051119 - sugar transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET transporter"
                     /protein_id="HGS1394424.1"
                     /translation="MIGSIAAILTTFAFLPQVFRIVKTKDTGSIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            134932..135243
                     /locus_tag="ACL8C7_000148"
     CDS             134932..135243
                     /locus_tag="ACL8C7_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HGS1394425.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILEN
                     I"
     gene            135361..137340
                     /locus_tag="ACL8C7_000149"
     CDS             135361..137340
                     /locus_tag="ACL8C7_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGS1394426.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFDQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLLKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNGFRQYFSKENFLICTESDKVNLLEKMVESLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQSFGTEGKVSVAICKDSLLWDNQSSHVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFINIFEKIK"
     gene            137350..137664
                     /locus_tag="ACL8C7_000150"
     CDS             137350..137664
                     /locus_tag="ACL8C7_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HGS1394427.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            137695..138201
                     /locus_tag="ACL8C7_000151"
     CDS             137695..138201
                     /locus_tag="ACL8C7_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394428.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LSQFISPSPIIIFPIMLIVFSILATVEQFKLYGNRKEKLGITLMFVRIQMLISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            138281..139627
                     /gene="celB"
                     /locus_tag="ACL8C7_000152"
     CDS             138281..139627
                     /gene="celB"
                     /locus_tag="ACL8C7_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HGS1394429.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFTSKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            140007..140183
                     /locus_tag="ACL8C7_000153"
     CDS             140007..140183
                     /locus_tag="ACL8C7_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394430.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            140584..142797
                     /locus_tag="ACL8C7_000154"
     CDS             140584..142797
                     /locus_tag="ACL8C7_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIM-barrel domain-containing protein"
                     /protein_id="HGS1394431.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSQTGSFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFATEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTIQN"
     gene            complement(143019..143495)
                     /locus_tag="ACL8C7_000155"
     CDS             complement(143019..143495)
                     /locus_tag="ACL8C7_000155"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HGS1394432.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDHKSGPLGKRIEWNFAKFLISRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            143718..146921
                     /locus_tag="ACL8C7_000156"
     CDS             143718..146921
                     /locus_tag="ACL8C7_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HGS1394433.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSSADASTRVIEAKDG
                     AITISSHEKLRAALHRMVPIEAKKKYKLRFKIKTDNKVGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDAYTARLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESFDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVDRATFNQMIKELESSLIDNNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            147274..147650
                     /gene="tnpA"
                     /locus_tag="ACL8C7_000157"
                     /pseudo
     CDS             147274..147650
                     /gene="tnpA"
                     /locus_tag="ACL8C7_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775157.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            147832..147894
                     /locus_tag="ACL8C7_000158"
                     /pseudo
     CDS             147832..147894
                     /locus_tag="ACL8C7_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596946.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(148038..148667)
                     /locus_tag="ACL8C7_000159"
     CDS             complement(148038..148667)
                     /locus_tag="ACL8C7_000159"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HGS1394434.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(148677..149678)
                     /locus_tag="ACL8C7_000160"
     CDS             complement(148677..149678)
                     /locus_tag="ACL8C7_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HGS1394435.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(149709..150350)
                     /locus_tag="ACL8C7_000161"
     CDS             complement(149709..150350)
                     /locus_tag="ACL8C7_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HGS1394436.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKGYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(150369..151184)
                     /locus_tag="ACL8C7_000162"
     CDS             complement(150369..151184)
                     /locus_tag="ACL8C7_000162"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HGS1394437.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIQAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNTEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            151454..151888
                     /locus_tag="ACL8C7_000163"
     CDS             151454..151888
                     /locus_tag="ACL8C7_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGS1394438.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            151900..153090
                     /locus_tag="ACL8C7_000164"
     CDS             151900..153090
                     /locus_tag="ACL8C7_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HGS1394439.1"
                     /translation="MIKKVTIEEIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELAHHDLGFLYTPSCMAEYKINGDGEAREAALKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            153101..153592
                     /locus_tag="ACL8C7_000165"
     CDS             153101..153592
                     /locus_tag="ACL8C7_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS1394440.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKNVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKAALKELNQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            153607..154386
                     /locus_tag="ACL8C7_000166"
     CDS             153607..154386
                     /locus_tag="ACL8C7_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGS1394441.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            154373..155191
                     /locus_tag="ACL8C7_000167"
     CDS             154373..155191
                     /locus_tag="ACL8C7_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGS1394442.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            155191..155484
                     /gene="yajC"
                     /locus_tag="ACL8C7_000168"
     CDS             155191..155484
                     /gene="yajC"
                     /locus_tag="ACL8C7_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HGS1394443.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            155506..157407
                     /locus_tag="ACL8C7_000169"
     CDS             155506..157407
                     /locus_tag="ACL8C7_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HGS1394444.1"
                     /translation="MKEERRQFFERIDGNQCRDYILPHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYLVEGDKSYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPMLAIYYFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHRRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            157467..158468
                     /locus_tag="ACL8C7_000170"
     CDS             157467..158468
                     /locus_tag="ACL8C7_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS1394445.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(158578..158913)
                     /locus_tag="ACL8C7_000171"
     CDS             complement(158578..158913)
                     /locus_tag="ACL8C7_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394446.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPIQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(158924..159166)
                     /locus_tag="ACL8C7_000172"
     CDS             complement(158924..159166)
                     /locus_tag="ACL8C7_000172"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394447.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(159182..159376)
                     /locus_tag="ACL8C7_000173"
     CDS             complement(159182..159376)
                     /locus_tag="ACL8C7_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS1394448.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            159542..160492
                     /gene="rsmH"
                     /locus_tag="ACL8C7_000174"
     CDS             159542..160492
                     /gene="rsmH"
                     /locus_tag="ACL8C7_000174"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HGS1394449.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            160504..160821
                     /gene="ftsL"
                     /locus_tag="ACL8C7_000175"
     CDS             160504..160821
                     /gene="ftsL"
                     /locus_tag="ACL8C7_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HGS1394450.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            160825..163077
                     /gene="pbp2X"
                     /locus_tag="ACL8C7_000176"
                     /gene_synonym="pbpX"
     CDS             160825..163077
                     /gene="pbp2X"
                     /locus_tag="ACL8C7_000176"
                     /gene_synonym="pbpX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HGS1394451.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGVT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            163079..164059
                     /gene="mraY"
                     /locus_tag="ACL8C7_000177"
     CDS             163079..164059
                     /gene="mraY"
                     /locus_tag="ACL8C7_000177"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HGS1394452.1"
                     /translation="MFISLSAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVYLGIFYIVFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            164668..166773
                     /locus_tag="ACL8C7_000178"
     CDS             164668..166773
                     /locus_tag="ACL8C7_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HGS1394453.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTSEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSQLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMKDGVLVIREKA"
     gene            complement(167068..167550)
                     /locus_tag="ACL8C7_000179"
     CDS             complement(167068..167550)
                     /locus_tag="ACL8C7_000179"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HGS1394454.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRIRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(167645..169129)
                     /locus_tag="ACL8C7_000180"
     CDS             complement(167645..169129)
                     /locus_tag="ACL8C7_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HGS1394455.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            169282..170889
                     /locus_tag="ACL8C7_000181"
     CDS             169282..170889
                     /locus_tag="ACL8C7_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HGS1394456.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWKYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAHEALEKGIPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTAAKEVLEKQVLAPWDAFCVELL"
     gene            171054..171221
                     /locus_tag="ACL8C7_000182"
     CDS             171054..171221
                     /locus_tag="ACL8C7_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HGS1394457.1"
                     /translation="MKKRILSAGLTFTSDLLLAACGQSGSDTKTYSSTFSGNPTTFNY
                     LLDYYADNIVN"
BASE COUNT        51654 a        30767 c        37153 g        51657 t
ORIGIN      
        1 aatagtccat gctgtggctg gattcttttc agcctactta tactcttcga aactctcttc
       61 aaaccacgtc agcttcacct tgccgtaggt atggttactg acttcgtcag ttctatccac
      121 aacctcaaaa cagtgttttg agctgactac gtcagttcta tctgcttttc attgagtact
      181 attaagacaa tatgaggaga aagatgaaag aaaaaggatt ttaggagggg gcgcaggcag
      241 ccatgccaac ggctcttggc tatgtcagta tcggcctggc ctgtgggact atcggtgcgc
      301 cctatgtgac acctgttgag atgggcttga tgagtctctt tgtttatgct gggagtgccc
      361 agtttgccat gttggcactg attgtggttc aagctcctgt ggcagctatt gctatgacgg
      421 tttttctaat caacttgcgt ctctttttgt tgagtttaca cgcatcgact tatttccgtc
      481 ataccagtct ttggtacaat atcggtatgt ctagtatctt gacagatgag acctatggcg
      541 ttttgatggg tgaattggcc catacagaca aggtaaatcc tatgtggatg cacggaaaca
      601 atcttaacag ctatgtggct tggtttgtgg ggacagtagt cggaacggct ctgggtggcc
      661 tgctaccaaa tccagaaatc tttggcttgg attttgccct ggttgggatg tttattggta
      721 tttttgcttc gcaatttcag attatgcaaa gacggattcc tgtccgcaat ctgctcatta
      781 tcctagcagt tgttgcggtg tccttctttt tgctcttgac agtggtgtct cagtcactag
      841 ctgttctgtt tgcgacgcta cttggttgta gcatgggggt ggttttagat ggtcagtaag
      901 tatcttttat tagcagttat tttctctgtc ttggtgactt ggattctccg tatgattccc
      961 ttcatcttag tcaagtataa gggcttgcct gcaatcgttg agcgtttttt gaagttcttg
     1021 cccgtttcca ttatctttgc cttgattctt tcaagcgtag tgacaggtaa ggttgggagc
     1081 cttcctcaaa ttaaatggct agacttctta gccgtctttc caacagcttg ggtagccttt
     1141 cgctaccgca atctagtcgg aacagttctc tttggagtgg tcttgattgc catcttgcgt
     1201 ttggtctttt aaattaccca taaaaaaaac ttatcacaga gatagatatc atataatggc
     1261 gtaaatgctc tttttctgtt aagattataa ggtattctat tttggaggaa atgacatgaa
     1321 aaaaatcgtt aaatactcat ctcttgctgc cctaggactt gttgctgcag gtgtgcttgc
     1381 ggcttgctca gggggtgcta agaaagaagg agaagcagct agcaagaaag aaatcatcgt
     1441 tgcaaccaat ggatcaccaa ggccatttat ctatgaagaa aatggcgaat tgactggtta
     1501 cgagattgaa gtcgttcgcg ctatctttaa agattctgac aaatatgatg tcaagtttga
     1561 aaagacagaa tggtcaggtg tctttgctgg tcttgacgct gaccgttaca atatggctgt
     1621 caacaatctt agctacacta aagaacgtgc ggagaaatac ctctatgccg caccaattgc
     1681 ccaaaatcct aatgtccttg tcgtgaagaa agatgactct agtatcaagt ctctcgatga
     1741 tatcggtgga aaatcgacgg aagtcgttca agccactaca tcagctaagc agttagaagc
     1801 atacaatgct gaacacacgg acaacccaac tatccttaac tatactaagg cagacttcca
     1861 acaaatcatg gtacgtttga gcgatggaca atttgactac aagatttttg ataaaatcgg
     1921 tgttgaaaca gtgatcaaga accaaggttt ggacaacttg aaagttatcg aacttccaag
     1981 cgaccaacaa ccgtacgttt acccacttct tgctcaaggt caagatgagt tgaaatcgtt
     2041 tgtagacaaa cgcatcaaag aactttataa agatggaact cttgaaaaat tgtctaaaca
     2101 attcttcgga gacacttatc taccggcaga agctgatatt aaataatttc ttgaaatcat
     2161 ccattctgag taaggtgggt ggtttctcag tttttaggga tatagtttta aactatatat
     2221 ctgactatct aataacaatt tgtgaaatca aacaaattgt gagatactag tacggtatta
     2281 tttttaagga gaaagaatca tgaaaatcaa aaaatggctt ggtctagcag cccttgctac
     2341 agtcgcaggt ttggctcttg cagcttgcgg aaactcagaa aagaaagcag acaatgcaac
     2401 aactatcaaa atcgcaactg ttaaccgtag cggttctgaa gaaaaacgtt gggacaaaat
     2461 ccaagaattg gttaaaaaag acggaattac cttggaattt acagagttca cagactactc
     2521 acaaccaaac aaagcaactg ctgatggcga agtagatttg aacgctttcc aacactataa
     2581 cttcttgaac aactggaaca aagaaaacgg aaaagacctt gtagcgattg cagatactta
     2641 catctctcca atccgccttt actcaggttt gaatggaagt gccaacaagt acactaaagt
     2701 agaagacatc ccagcaaacg gagaaatcgc tgtaccgaat gacgctacaa acgaaagccg
     2761 tgcgctttat ttgcttcaat cagctggctt gattaaattg gatgtttctg gaactgctct
     2821 tgcaacagtt gccaacatca aagaaaatcc aaagaacttg aaaatcactg aattggacgc
     2881 tagccaaaca gctcgttcat tgtcatcagt tgacgctgcc gttgtaaaca ataccttcgt
     2941 tacagaagca aaattggact acaagaaagc acttttcaaa gaacaagctg atgaaaactc
     3001 aaaacaatgg tacaacatca ttgttgcgaa aaaagattgg gaaacatcac ctaaggctga
     3061 tgctatcaag aaagtaatcg cagcttacca cacagatgac gtgaaaaaag ttatcgaaga
     3121 aacatcagac ggtttggatc aaccagtttg gtaataagaa acagggaggt gggagagaaa
     3181 attccacctc ttgcttttgt atagagtata gattgtaaag aagactattc gttcatagaa
     3241 aggtagagag aatatggttt ttcctagcga acaagaacag attgaaaaat ttgaaaagga
     3301 tcatgtagtc caacattatt ttgaggtttt gcgtaccttg atttctaaga aatcagtctt
     3361 tgcccagcag gttggactca aggaagtcgc aaattatctg ggtgagattt tcaagcgtgt
     3421 tggagctgaa gtggagattg atgagagcta tacagcgccc tttgtcatgg cacatttcaa
     3481 gagttcgcgt ccagatgcca agaccttgat tttctataac cactatgaca ctgtgccagc
     3541 ggatggggat caggtctgga cagaggatcc ttttacgctt tcggtccgca atggcttcat
     3601 gtatgggcgt ggggttgatg acgacaaggg tcatatcaca gctcgcttga gtgctttgag
     3661 aaaatatatg cagcaccatg atgatttacc tgtcaatatc agctttatca tggagggagc
     3721 ggaggaatcg gcttcaacag acctagataa gtatttggaa aagcatgcag acaaactccg
     3781 tggggcggat ttgttggtct gggaacaagg gaccaaaaat gccttggaac agctggaaat
     3841 ttctggtggc aataagggga ttgtgacctt tgatgccaag gtaaaaagcg ctgatgtgga
     3901 tatccactcg agttatggtg gcgttgtgga atcagctcct tggtatctcc tccaagcctt
     3961 acagtctctt cgtgctgcgg atggccgtat cttggttgaa ggcttgtacg aagaagtaca
     4021 cgagcccaat gaacgagaaa tggccttgct agaaacttat ggtcaacgaa acccagagga
     4081 agttagtcgg atttatggat tggagttgcc tctcttacag gaggagcgga tggcctttct
     4141 aaaacgtttc tttttcgagc cagcgcttaa tatcgaagga atccagtctg gttatcaagg
     4201 tcaaggtgtt aagactattt tgcctgcaga agccagtgcc aagctagagg ttcgtctggt
     4261 tccgggccta gaaccgcatg atgttctgga aaaaattcgg aaacagctag acaaaaatgg
     4321 ctttgataag gtagaattat actatacctt gggagagatg agctatcgaa gcgatatgag
     4381 cgcaccagcc attctcaatg tgatcgagtt ggccaagaaa ttctatccac agggcgtttc
     4441 agtcttgccg acgacagcgg ggacaggacc tatgcatacg gtctttgatg ccctagaggt
     4501 accaatggtt gcattcggtc taggaaatgc caatagccga gaccacggtg gagatgaaaa
     4561 tgtgcgaatc gctgattatt acacccatat cgaattagta gaggagctga ttagaagcta
     4621 tgagtagaga tattatcaag ttagatcaga tcgatgtgac ttttcaccaa aagaagagaa
     4681 ccatcacagc ggttaaggat gtgaccattc acatccaaga aggggatatc tacggaatcg
     4741 ttggatattc tggagcaggg aaatcaaccc ttgtacgggt gattaacctc ttgcaaaaac
     4801 catctgcagg gaaaattacc attgacgacg atgtgatttt tgatggtaag gtcaccttga
     4861 cggcagagca gttgcgtcgt aaacgtcaag atatcgggat gattttccag cattttaacc
     4921 tgatgagcca aaagacagca gaggagaatg tagcctttgc ccttaaacac tctggactca
     4981 gcaaggaaga aaagaaggct aaagtagcta agttgttgga cttggttggt ttggcagatc
     5041 gtgctgaaaa ctacccttca caactatctg gagggcaaaa acagcgtgtg gcaattgcgc
     5101 gtgccttggc caatgatcca aaaatcttga tttcagacga gtcaacttct gcccttgacc
     5161 ctaagacaac caagcagatt ttgaccttgt tacaagattt gaaccaaaaa ttaggattga
     5221 cagttgtctt gattacgcat gaaatgcaga ttgtcaaaga cattgccaac cgtgtggcgg
     5281 ttatgcagga tgggcatttg attgaagagg gaagtgtcct tgaaatcttc tcagacccta
     5341 aacaaccttt gactcaagac tttatctcaa cagccacagg tattgacgaa gccatggcca
     5401 aaatcgagaa gcaagaaatc gtggaacact tgtctgaaaa cagtctcttg gtgcaactca
     5461 agtacgctgg agcttcaaca gacgagccac ttttgaatga attgtacaag cattaccaag
     5521 taatggctaa tattctctat gggaatatcg aaattctcga tggtactcct gttggagaat
     5581 tggtggtggt cttgtcaggt gaaaaagcag cgttggcagg tgcccaagaa gccattcgtc
     5641 aagcaggtgt acaactaaaa gtattgaagg gagtacagta agatggaatc attgattcaa
     5701 acctatttac caaatgtcta taaaatgggt tgggctggtc aggcaggctg gggaacggct
     5761 atctacttaa ctctttatat gacagttctt tccttcatta tcggaggctt cttggggcta
     5821 gtggcaggtc tctttctcgt cttgacagcg ccaggtggtg tcttggagaa taaagtcgta
     5881 ttctggattt tagacaaaat tacctcaatt tttcgtgcgg ttccctttat catcctcttg
     5941 gcaatcttgt caccactttc tcacttgatt gttaaaacaa gtatcgggcc aaatgcagcc
     6001 cttgtcccac tttcttttgc agtctttgcc ttctttgccc gtcaggtgca ggttgtcttg
     6061 gctgaattgg atggcggtgt cattgaggcg gctcaagcga gcggagcgac tttctgggac
     6121 atcgtgggtg tttacctatc agaaggtctt ccagatttga tccgtgtgac gactgtgacc
     6181 ttgatttccc ttgttgggga aacagctatg gccggtgcgg ttggagctgg tggtatcggt
     6241 aacgtagcca tcgcttatgg atttaaccgc tacaatcacg atgtgaccat cttggcaacc
     6301 atcattatca ttttgattat ctttgcaatc caattcttgg gagatttctt gactaagaaa
     6361 ttgagccata aataaaaaag agccgtgtgg ctctttttaa ctgatcagat tttctgtgca
     6421 aattttttac tcaaggcttg tccaatcaag gcacccacta gggctccgat gacaatactt
     6481 gcgataaata gaaggacagt tccaggggtt ggagcgacca tgatacggtc gatatattct
     6541 tgggattttc ctcttgccag aagagtagcc atataggctt tgggcgcaat ccacataagc
     6601 aagattggtc ctgttgtact aaaggcgaaa ataatgaaag aaaggaagtt ctttgttttg
     6661 tccttgtatt ttcctaaatg agctacttca tctgctagga ggccacagat aattccagga
     6721 aggaaggaac cagcaccgtg tttagttccc aagaaaaaga aggcaatgac aaggccgata
     6781 gtggtaatgg ctccaaagcg cggaactttt gcgactagga tcatatagac gctaccgccg
     6841 acaagggcag taaaggcagg cgcataaaac atgtttccag tttggtcaaa gagattgccc
     6901 aaaaggacac caatccccat gcagaggaag taaagaactg caaaaagcag tgtagttaag
     6961 atagattttt tcatgaattg tctcctgata attttttcac aattctcatt gtaccacggt
     7021 ttggtgggat tgtaaatgga tactagaagt ttttgaaaac gcttgaaata tgatataatg
     7081 gtttcatagt tatttttagg ggaatatcat gggtagattt ttagactttg tctttaatcg
     7141 tttcttttta gggatgattg cgacagcctt cttttggcta ttaactttag caggagggat
     7201 tatccttggt ctagcgccgg ctagtgccac cttgatgagc ttatatgcag aacatggtta
     7261 tagctttcgg gaatacagtt tgaaggaggc ttggtctctt tacaagcaaa attttgtctc
     7321 aagcaacctg attttctata gctttttagg tgtgggtcta gttttgacct atggtttgta
     7381 tctcttggtg caattgcctc atcagaccat tgttcatttg attgcgaccc ttttgaatgt
     7441 cctagtagtt gccctgatct ttttggctta tacagtatct ttaaaattac aagtttattt
     7501 tgccttgtcc tatcgaaata gtctcaaatt atccttgatt ggcatcttta tgagtctagc
     7561 agctgtggct aaggttctcc ttgggactgt gctacttgta gcaattggtt attatatgcc
     7621 tgccctgcta ttttttgtag gaattgggat gtggcatttc tttatcagtg atatgttgga
     7681 acctgtctat gaaatcatcc atgaaaaatt ggcgacaaaa tagaatgaag cagttttggc
     7741 tacatacgct tctaagaacc tatagttcag tgatgatcat tatcattgcg agttttgcaa
     7801 tcttactctc ttacgctgac tgggattcac gtgaaaagga agcccagaga gtagcccagc
     7861 gtgtaactgc tagaacagtg agtgaaattg aatattacca tagagagtca acccagatag
     7921 ctcaggcttt agttgaaaat caagctcgta tcgagggaat ctataaatac tttagcctta
     7981 gcatgccaga ctatttttac tggcaattag agcggaaagc ttcgccttat atatcagtct
     8041 ctctgtatga aaatgttgat gacctctatg ttcgaaatga ttttgtaact ggggtggcca
     8101 ttgcttttca agattacaag gaagtctatg tttctactaa agacaaacgt agtggagaaa
     8161 aaatcagggc tgaggatttc aaaccagcag gaaatagttt tgccattccg gtgtcagatc
     8221 cagtgtcaga tcaagattta ggagtgattt acatctcctt ggatcctgct gttttatacc
     8281 atgccattga taatactaga ggtcatactc cgatggcagt aacagtgacc tcaccttttg
     8341 atacggagat ttttcatatt ggtgagacag ttgataggga gagtgaaaat tggctagttg
     8401 gcttaacttc tcatggatat caggttcagg tggcagttcc taaaaacttt gttttacaag
     8461 gaacagtgac tagctctgct ttgattgtgg gtttgagcct tctctttatt gtcattcttt
     8521 atctgacttt gaggcagact tttgctaatt accaaaagca ggtagtggat ttagtggaat
     8581 ccattcaagt cattgctcaa ggcgaagagg ggcgtcggat tgacatttcc gaaaaagatc
     8641 aggaattact cctaatcgcg gagacgacca atgatatgtt ggatcgattg gaaaagaata
     8701 tccatgatat ttaccagtta gagcttagtc aaaaagatgc caatatgcga gccttgcagg
     8761 cgcaaatcaa tcctcatttt atgtataata cgctggagtt cttgcgcatg tatgcagtta
     8821 tgcagagtca agatgagttg gcagatatca tttatgaatt cagtagtctc ttgcgtaaca
     8881 atatttccga cgaaagagag accctcctca aacaggaatt agaattttgc cgtaaataca
     8941 gctatctctg catggttcgc tatcccaagt ccattgccta tggtttcaag atagatccag
     9001 agttagagaa tatgaagatt cccaagttta ccttgcaacc gctggtagaa aactatttcg
     9061 cgcatggtgt tgaccacagg aggacagata atgtcattag catcaaggct cttaaacagg
     9121 atgggtttgt ggaaattttg gtggtcgata atggtagagg aatgtcggct gaaaagttgg
     9181 caaatatccg agaaaaatta agtcagagat attttgaaca ccaagccagc tacagtgatc
     9241 aaaggaagtc tatcggaatt atcaatgtac acgagcgttt tgtgctctat tttggagacc
     9301 gctatgccat tactatagag tctgcagagc aagccggtgt tcagtatcgt attacaattc
     9361 aagatgagta gaaagggaga aaatgtataa agtattatta gtagatgatg agtacatggt
     9421 gacagaaggt ctgaagcgtt tgattccctt tgataagtgg gatatggagg tcgtcgcaac
     9481 agccagtcat gccgatgaag ctctagaata tgttcaggaa aatcctgtcg atgtcatcat
     9541 ttccgatgtc aatatgccag acaaaacagg gcttgatatg attcgggaga tgaaagagat
     9601 cttaccagat gctgcctata tcctgctctc aggttatcag gagtttgatt atgtaaaaag
     9661 agcaatgaac cttagtgtgg tggactattt ggtcaaacct gttgataagg tagagctggg
     9721 aaatctgctg gagaagattg caggtcagct cggcgagaga gggaagaaaa gtcagactct
     9781 tagtcaagaa ttagacgagg ctggatttgt tagttattta ggggataagg agaattggtg
     9841 gataggtcta tccaaggaaa aacaaggttc cttcaccatt ccctactatg tcttgggcca
     9901 agactggcag attttcattt ctgaccaacc cctagatggt ttagtcgtta caccttttga
     9961 agctccttat caagaacact ttgaacgctg gaagctgaat gctgagaaaa ccctctttta
    10021 cggttctgta aatttgcagc agtctgagag tctctttgcc tattacgaac cgatttatag
    10081 ggttatcatt cagggaaatc tcaatcaaat cgtagaagag ttaaatctct tggagaaggt
    10141 agttcttgaa aatacgccgc gtgttccgat tactaaacag ctttttattc agtttgtcat
    10201 ggatgttttc catttatttg aacatctcaa agctgatgac ctgacagaca tcgtcaaaac
    10261 cattcatgct attcaatcct tcgatgaatt ggttccttat atcaaggaaa ctctgaccag
    10321 ctttttcggt caataccgta tgaatgaaaa tgtggtcagt gtgctggaag tcattggtcg
    10381 tgattaccaa aaagagcttt ccctcaagga tatcagtaag gctctcttta tcaatcctgt
    10441 ctatctaggg cagttgatta agcgtgaaac cgattcgact tttgcagagt tactaaacaa
    10501 acaacgtatt aaggctgccc aacaactttt gctttcaact agtgacagca tcgaagatat
    10561 ttgttatgct gttggttaca gtaaccttgg atatttctat aaagttttcc gaaaattgtg
    10621 cggaaaatcg ccaaaagcct accgaaaaca ggtagaaact atactataaa atttgtattc
    10681 ctttacaaaa ggtgctataa tattatcagg aggttctatc atgaaaaaga aaccaattta
    10741 tctatggatc ttgctaatct tgtctgccct tatttcagtt ccgtctctgt ttggaattgt
    10801 gagtcccttg cctagtaaag aagcccttcg tgctgctcag aaacaagttg caggggtcaa
    10861 tgctcagcaa ttagaagacc agcttaatta tacctataga gtagcagaag catctcattc
    10921 tatttttaat gttgctttga ttgtgctatc tactatttta gtggtcgtag cgattgtctt
    10981 ccttgttcgt aaaaatttgc aatatgcaaa ctatacttac gttggctatg ttttgttagc
    11041 tattattggt tcgatttatg gctatgttgg tttacaagac gctgtgcagt tggttcaaga
    11101 tgagagcatg cgtttgacag tgagtattgg ttcaaaagct gttagcattt tctatatcgt
    11161 catcaatgtt ctcttcctag cccttgtctt ctataagatg tggcgacaac agaaagcctt
    11221 ggcagaagaa gaggaaacag aagagcttgc ctaagtattg acaaaaaaga actatcaaga
    11281 tacaatcttg gtagttgttt tttgattata gataaaatca tggaggtaca tatgaagaca
    11341 atttctttag tttatattag tttgagtggc aacactgaaa gttttgtgac gcgcttgaaa
    11401 gactatctct tgtcccagta caaagggatt gaggttcaaa agattcatat caaggatttg
    11461 gtcaaggaag gcaaaaattt ctatgaaatg gaccatccct atgtcgcttt tttgccgacc
    11521 tatctcgaag gtgggaatgg cgtggataac ggagatgttg agattttgac gacaccggtg
    11581 ggagatttta ttgcctatgg taacaatgct agtaagtgtt ttggtgtggt tgggtcagga
    11641 aatcgtaact ttaataacca atactgccta acagccaagc aatacagtca acgctttggc
    11701 ttccctgtat tggctgactt tgaaatgcga ggcatgctgg aagatatcaa acatgtcgca
    11761 gctattatcg cagatttgta tgagttggaa aaggagaatt aatactcaat gaaaatcaaa
    11821 gagcaaacta ggaagctagt cgcaggttgc tcaaagcaca gctttgaggt tgcagataga
    11881 gctgacgtgg tttgaagaga ttctcgaata gtataaagtt cttataagag atggttgaag
    11941 ttgttcaact gttttttgag tataaacagt ctttaagaac gtaaaaaagc ataagttcag
    12001 gtcttcaaaa ccttgttctt atgcttttta tcatagaaat atttgctgaa ttttctcttg
    12061 aaatgaaacc ttatcttcat ctcgcgcttg tcccttaccc tgcttttccg attgcgagtg
    12121 cgtagataaa gaagatggcg aagccaaaga ggaaaatcaa tcccgcaatg gcaaggtgtt
    12181 tgagccaaga aggaagattt ttgttttcac gcgttaccaa ggcgtaattc aaaagagcaa
    12241 agaaaggtgt tgtcaggaaa gatccaatca tggcaaagcg gagcatggtt gaaacctgac
    12301 cagcgaagaa cttgataatg acgataccga tgatagcagt gatggtcatc cagatgttca
    12361 aagatttacg attgtcctct ttttgactga ttagcagtcg gagagattcc tgattaacgc
    12421 gagaatagcc atcgataaca gttataactg ttccaaagat acagaggaag gcaataaagg
    12481 taatcaagta acgggaccat tcgccaagaa cagaggcata catgcccacg aattgagaga
    12541 tgtatttggc tgaagcagct tcaaccgcct gccctgtagg atactgaatc agtgctccca
    12601 gtgccacaaa gaagacggct aggatagctg ttccaatata accagtgtta aagtcaaaca
    12661 gagcgtcttc tgtgttaaag ttgacggtct ttctcttttc agctgaccaa agtgaattga
    12721 tggctgaaat ttcaatagga gccggcatcc atcctaggag ggagacgatg aagggcagag
    12781 ctgccatttg ccaaggtgtc ttctcgacaa aatcagaact gtattctgga tgcttgaccg
    12841 ccgcaatgat aactgccaga acagtcgcaa tggttaaggc agacataatc catttgacca
    12901 tgccgtctaa aagtttgtag cctccaaaga gtagcatagc ccaaatgatt gcaacgagaa
    12961 tgagggacca ctgagtaatg ctaagtccaa tcattgggaa ggcactggcg atgatagctg
    13021 agcacagaat ggcaacacca gccgtgttga ccatagccga aaagacattg aggataaaga
    13081 aaatccagag atagagtttt cctttttcgg cataaccttc aaccaaagtc tttccagtat
    13141 cagctgtgta ttcagcacca aaacggaaaa atggatattt aaagacattg gctaagatga
    13201 ccaagagaag tagagaccaa ccgtaagaac cgccagcttg agttgaggat acaatgtggg
    13261 aacctccaac agcggcagtt gccattagga ttccaggtcc cattgctttt agcttgcttg
    13321 cccaggttga ttgatttaag gaaatagctt gcgacatgat aaatactcct ttttgaattt
    13381 tcagaataat ctgtatatgt aatctatatt ctacaaaaaa ttttggaaaa atgcaagagt
    13441 attttgaaaa aagatagaaa atttacaaag aagatctgaa ataactatta tgatatagcg
    13501 gattgaaact agaatagtac acctttgctt ctaaaacatt gttagaaatc tatttgactg
    13561 tcctgatcga tttatcctgt tcttatttca tttcactata gtaaggtgca gcaggataaa
    13621 gaaaaaccga gaagtttctt tctcggattt gcttattatg aggttcctat tttctatgct
    13681 ccaagagttg attgatgtga tctacttttt tagcctctct tttatagaga atagcccaga
    13741 tgatgagata gacaatcgca aactcgataa tgagctggag gtagaaaatc cagtggaaag
    13801 ggaaccaacc agcaagagtt gctagtggga caaagccagc cagcataagg aagaaatgag
    13861 tcagagtggc acgaagcatg ctccagtcac ggctgaataa gcggttgcca aagttgaaga
    13921 gcataccgat ggctgcccag ataagtgtgc agtagagcaa gaccagggca ccgtgaacct
    13981 gatgctgatc catcacttgg ccgatgagag agtagggatt tagtggtgcg taggtatttg
    14041 gtgcataaat gagtgaaaag aggatggaga ggatgaggcc gataagaaca ccggcagctg
    14101 catcgtgaaa tacttgtttt ttcatagttc taatttctcc ttgatggttt ttagataacg
    14161 gcgtgaagag taggtgaagc tttcgttttt caagaaaatt tctaccagac cgtttggcgt
    14221 gagcttgagg tgagagatgg aatcgatatt gatgatttct gattgggaaa tttggataaa
    14281 attggttggc aagagtttaa gaacctgata gagtcgcaaa tcaatgctgt aggtctgact
    14341 cgcggtttct gctagaacct tccgattctc gatatagaag cgctgaatct tgccaatctc
    14401 aactagatag acctgatcat cgatttttcc tttgattttt tctctttggt ccagattttc
    14461 tgcgaactcg atgactttct ggactttttc ggtttcttga ggtgcttgga caatcagctt
    14521 ttcctcctcg taagtctcac taatctgtag ttctactttc ataaatttct ctccttgttt
    14581 ttcatacaaa attaatctca cttcttgtac acctttatta atactcttca aaaatctctt
    14641 caaaccacgt cagcgtcgtc ttgccgtagg atagttgttg actttgtcag ttttatctac
    14701 aacctcaaaa cagtgttttg agctgtctgc gtctagcttt ctagtttgct ctttgatttt
    14761 tattgagtat accactattt tactccctct ggcaagggac tttgtctatg tggagggatt
    14821 gggctcctat gtggtggagt ttttctgttc tttctgaaat atggtataat agcactaatt
    14881 aatttctagg aaaatagata cagaaagggg ctgaaagatg tctcatatta ttgaattgcc
    14941 agagatgctg gcaaaccaaa tcgcagctgg ggaggtcatt gaacgtcctg ccagtgtggt
    15001 taaagagttg gtagaaaatg ccattgacgc gggctctagt cagattatca ttgagattga
    15061 ggaagctggt ctcaagaagg ttcaaatcac ggataacggt catggaattg cccacgatga
    15121 ggtggagttg gccctgcgtc gccatgcgac cagtaagata aaaaatcaag cagatctctt
    15181 tcggattcgg acgcttggtt ttcgtggtga agccttgcct tctattgcgt ctgttagtgt
    15241 cttgactctg ttaacggcgg tggatggtgc tagtcatgga accaagttag tcgcgcgtgg
    15301 gggtgaagtt gaggaagtca tcccagcgac tagtcctgtg ggaaccaagg tttgtgtgga
    15361 ggatctcttt ttcaacacgc ctgcccgtct caagtatatg aagagccagc aagcggagtt
    15421 gtctcatatc attgatattg tcaaccgtct gggcttggcc catcctgaga tttcttttag
    15481 cttgattagt gatggcaagg aaatgacgcg gacagcaggg actggtcaat tgcgccaagc
    15541 aatcgcaggg atttacggtt tggtcagtgc caagaagatg attgaaattg agaactctga
    15601 cctagatttc gaaatttcag gttttgtgtc tttacctgag ttgactcggg ctaaccgcaa
    15661 ttatatcagc ctcttcatca atggccgtta tatcaagaac ttcctgctca atcgtgctat
    15721 tttggatggt ttcggaagca agcttatggt tggacgtttt ccactggctg tcattcacat
    15781 ccatatcgac ccttatctag cggatgtcaa tgtgcatcca actaagcaag aggtgcggat
    15841 ttccaaggaa aaagaactga tgaccctggt ttcagaagct attgcaaata gtctcaagga
    15901 acaaaccttg attccagatg ccttggaaaa tcttgccaaa tcgaccgtgc gcaatcgtga
    15961 gaaggtggag caaactattc tcccactcaa agaaaatacg ctctactatg agaaaactga
    16021 gccgtcaaga cctagtcaaa ctgaagtagc tgattatcag gtagaattga ctgatgaagg
    16081 gcaggatttg accctgtttg ccaaggaaac cttggaccga ttgaccaagc cagcaaaact
    16141 gcattttgca gagagaaagc ctgctaacta cgaccagcta gaccatccag agttagatct
    16201 tgctagcatc gataaggctt atgacaaact ggagcgagaa gaagcatcca gcttcccaga
    16261 gttggagttt ttcggacaaa tgcacgggac ttatctcttt gcccaagggc gagatggact
    16321 ttacatcata gatcagcacg ctgctcagga acgggtcaag tacgaggagt accgtgaaag
    16381 cattggcaat gttgaccaga gccagcagca actcctagtg ccctatatct ttgaatttcc
    16441 tgcggatgat gccctgcgtc tcaaggaaag aatgcctctc ttagaggaag tgggcgtctt
    16501 tctagcagag tacggagaaa atcaatttat tctacgtgaa catcctattt ggatggcaga
    16561 agaagagatt gaatcaggca tctatgagat gtgcgacatg ctccttttga ccaaggaagt
    16621 ttctatcaag aaataccgag cagagctggc tatcatgatg tcttgcaagc gatctatcaa
    16681 ggccaatcat cgtattgatg atcattcagc tagacaactc ctctatcagc tttctcaatg
    16741 tgacaatccc tataactgtc ctcacggacg tcctgttttg gtgcatttta ccaagtcgga
    16801 tatggaaaag atgttccgac gtattcagga aaatcacacc agtctccgtg agttggggaa
    16861 atattaaaag tataaaaaag tctgggaaaa attttcaaaa tcagaaaaac gcataaaatc
    16921 aggtgttcaa aaaccttgat tttatgcgtt ttatcatgga aatagttact tcatgttttc
    16981 ctaattcttt tcgaaactct ttttaaacca cgtcagtttt atcagtaatc tcaaaacagt
    17041 gttttgagct aattttgcca gttttgtctg taacatcgaa gttgtgtttg accactctgc
    17101 gactggtttc ctagtttgct ctatgatttt cacagagtat taaattgcga ttttgccaag
    17161 tttctttatt cgtctaaaag tagagtctgt tctatgcgtc taatgtacga attaggttga
    17221 ccatttcaat agctccttgt gcacactcag aacccttatt tcctgcttta gtgccagctc
    17281 gttctatggc ttgttcaatt gtatctgtcg ttagcacacc aaacataaca ggaatttcgc
    17341 tatttaaact gatttgggcg attcccttag atacctcgct acatacataa tcataatgac
    17401 ttgtattccc tctaatgaca gctcccaagc agataattgc atcatatttt ttactttttg
    17461 ccatttttga tgcaatcagt ggtatttcaa aagctcctgg aacccaggct acctctatat
    17521 ctttctcgtt tacattctct cttttgagat tatctagtgc tccagataat aattttgaag
    17581 ttataaattc attaaatctc gctacaacaa tacctatttt aatattgttt gctactaaat
    17641 taccttcata agtgttcatt tatttttcct ccatatttaa aatgtgaccc attcgatttt
    17701 tctttgtttc taaataaaaa ctatcgtaag gattggcttc tatttcgatt gatattctac
    17761 tggaaatggt aattccatat ttttctaact gttcaacctt gtcaggatta tttgtcagta
    17821 aatgaagtga ctgaagtccc agatctttaa gcatttgtgc tccaatatga tattctctta
    17881 aatcaccttc aaagcctaat gcaagattgg catcaagcgt atccatgcct tgatcttgta
    17941 aatgataggc ttttaattta ttgataagtc caattcctcg tccctcctgt cgcaagtaaa
    18001 gtaagacacc cgaaccattc tcaacaatca ttttcatagc tttatcgaat tgctgtccac
    18061 aatcgcaacg taaggagcct aaaacatccc ctgttaaaca ttcggagtgg acccgacata
    18121 atacattggc ttcatcctct atgtttccca taataagagc aagatgatgt tccccattta
    18181 gtttatctat atagctaatt gctttgaaat taccgtatct agtaggcata ttgacagttg
    18241 aaactcgttc taccagctga tcatatactt ttctatattc ttgtaattct ttgatggtaa
    18301 ttagtggaat gttgtgtttc ttcgagaact gaattaaatc atctgttctc atcattttgc
    18361 catcatgatt cattatttca caacataggc cacactcttt tagtccagct aattttaata
    18421 aatcaacagt tgcttctgtg tgtccacttc tttctagaac accacctttt tttgcaatta
    18481 aaggaaacat gtgtcctggc ctgcgaaaat cagagggtgt tatatcttca gctacacaca
    18541 tacgtgcggt cagtcctctt tcctcggcag aaatacctgt ggtcgtttct ttataatcaa
    18601 ttgaaactgt aaaagcagtc ttatgattat ctgtattgtt ttcaaccata ggtgaaagca
    18661 ttaattgatt agctaaactt tcgctcatag gcatacaaat taatcctttg gcataagtag
    18721 ccataaaatt aacattttct gttgtagctg cttgtgcaga acaaattaag tctccttcat
    18781 tttctctatc cttgtcgtct ataacaagaa caagtcgtcc cttctgcaat gcttctaatg
    18841 cttcttgtat ttttcgatat tccattgact gattatcctt tctgctaaaa tccattttga
    18901 tataatagtt ccttagatat ttctgatttt ggagagttat ccatcagttt ttgcacatat
    18961 ttacctaaga tatcattttc aagatttact gtactcccga cttgtttact cttaagaatg
    19021 gtttgttcca aggtatgagg gataacagat actgaaaagt ttactttgga gactttagcg
    19081 acagtcagac taatgccgtc aattgtaata gatccttttt caactattaa atctaaaatt
    19141 tctttttgtg tgttgatttg ataccataca gcattatcat ctttttttat tgacgagatt
    19201 tttcctgtac catcaatgtg tcctgtaacg acgtgacccc caagtcgacc gttgacagat
    19261 aaggctcttt ctagattcac ctcacttcca tgttttaata gagtaagagc tgttcgactc
    19321 catgtttcat tcattacatc aactgtaaag gattgatgat tgaaatgagt aactgtaaga
    19381 cagataccat ttactgctat actatcgcct aaatggatat ccgttaatat ttttgaggct
    19441 ttaattgata gtttacaatt acgagagtct ttctgtattc tttcaacttt tccgatttct
    19501 tcaattattc ctgtgaacat ggataaatca cttcactttc tatgagatag tcatttccta
    19561 tttgagaaaa tgcataaggt ttcaatctaa tagcgtcatt tggcaaagaa ataccttcac
    19621 ctccgacagg aaacttggca ctacctccaa aaatttttgg tgcaatatat attttcagct
    19681 catcaacaat ttgttgttcc aaagcactcc aattcattag actgccccct tctagaacta
    19741 ggctatcaat ctgcatgttt cctagatgtt gcattaaact cgataagtct atatgattgc
    19801 cttttttctt tatggaaagt atttcacagc catgattttg atatagcttc attttatttt
    19861 tgtcttcaga ggaagtggca atgtaagttt taatatcatt tgctgttttt acgattttag
    19921 aggtaagagg agttcgtaaa tgtgtatcgc atatgatacg gataggattt ttcccttcct
    19981 ccaatctaca tgtcagcaaa ggatcgtctt gaataacagt attgactccc accataattg
    20041 cactaacatg gtgtcgtaac tgctgcacat gctttcttgc ttcttcttca gtaatccatt
    20101 tggattgatt tgttttagtg gctatttttc catccattga cattgcatat ttcataaaaa
    20161 catagggtac atgctgggta atatactttc taaaactttt tattaagtta agacactcat
    20221 tttctaaaat tccaacagta acttgaagat tattttcctc aagtatcttt actccttttc
    20281 cagatacaat aggattacag tctaggcttc caatgactac tcttgtaata ccactatcga
    20341 ttatagcatc tatacaggga ggtgttttcc cgaagtgaca acagggttca agtgttacat
    20401 aaagcgtcgc tccgacaggg gattctctac agtttttaag agcatttctc tcagcatgtg
    20461 ggccaccaaa aaactcatga taaccttgtc cgataatgtg attatctttt acaataactg
    20521 cgccgaccat aggattggga ttgacgtaac cagccccttt ttgtgccagt tttattgcta
    20581 atttcatata ttttgaatcg ctcatctcac tacctccaaa aaaatatgcc ttgaataggg
    20641 gactactcaa ggcatacaaa agaaaactta tgcgattaac aaaaatgctc tgaaatgaca
    20701 agtaatcatt tcagagcacg caaaaagcac aaatatactt ttatcttctt tcatccagac
    20761 tatactgtcg gctttggaat ttcaccaaat catgcctttc ggctcgtggg ctataccacc
    20821 ggtagggaat ttcaccctgc cctgaagata gttattcaat tacagatgat tatagtactt
    20881 aattttgaat atgtcaacag ataaataccg attgtttttg atatactgta tttgtgataa
    20941 tcgattctcg ctcctcggat aaagaaaata tgatatacta gataaacgaa ataagagaga
    21001 aggaatacta tgtacgcata tttaaaagga atcattacca aaattactgc caaatacatt
    21061 gttcttgaaa ccaatggtat tggttatatc ctgcatgtgg ccaatcctta tgcctattca
    21121 ggtcaggtta atcaggaggc tcagatttat gtgcatcagg ttgtgcgtga ggacgcccat
    21181 ttgctttatg gatttcgctc agaggatgag aaaaagctct ttcttagtct gatttcggtc
    21241 tctgggattg gtcctgtatc agctcttgct attatcgctg ctgatgacaa tgctggcttg
    21301 gttcaagcca ttgaaaccaa gaacatcacc tacttgacca agttccctaa aattggcaag
    21361 aaaacagccc agcagatggt gctggacttg gaaggcaagg tagtagttgc aggagatgac
    21421 cttcctgcca aggtcgcagt gcaagcaagt gctgaaaacc aagaattgga agaagctatg
    21481 gaagccatgt tggctctggg ctacaaggca acagagctca agaaaatcaa gaaattcttt
    21541 gaaggaacga cagatacagc tgagaactat atcaagtcgg cccttaaaat gttggtcaaa
    21601 taggagcaga gaatgacaaa acgttgttcg tgggtcaaga tgaccaaccc gctctacatc
    21661 gcctatcatg atgaggagtg gggccagccc ctccatgatg accaagtatt gtttgagttg
    21721 ttgtgtatgg aaacctatca ggcaggcctg tcttgggaaa cggtactcaa caaacgccaa
    21781 gctttccgag aagtctttca tagctatcaa attcactcag tcgcagagat gactgacact
    21841 gaattggaag ccatgctgga gaatccagct atcattcgaa atagagccaa gctttttgct
    21901 acacgcgcta acgcccaagt ctttctacag ttacaggcag agtacggctc ttttgatgcc
    21961 tatctttggt cttttgttga ggggaaaact gtcgttaacg atgttcctga ttatcgccaa
    22021 gcgccagcta aaacaccctt atctgagaaa ttagccaaag atctcaaaaa acgaggcttc
    22081 aagttcatag gcccagtcgc cgtattgtct tttctacagg ctgcagggct agttgatgac
    22141 cacgagaatg attgtgagtg gaaaggtctt aaatgatgtc taacaaaaat aagggaattc
    22201 tgatttttgc gattctctat acagtcctct ttgtgtttga tggcgttaaa ttgctggctt
    22261 ctttaatgcc atctgtcatt gcaaattatc ttgtttatgt agttttagct ttatatggct
    22321 ccttcttgtt caaggataga ttgatccaac aatggaagga gattagaaag actaaaagaa
    22381 aattcttctt tggcgtctta acaggatggc tctttctcat tctgatgact gttgtctttg
    22441 aatttgtatc agagatgttg aagcagtttg tgagactaga tggacaaggt ctaaatcagt
    22501 ctaatattca aagtaccttt caagaacaac cactactgat agctgttttt gcttgtgtca
    22561 ttggacctct ggtagaagaa ttatttttcc gtcaggtctt attgcattac ttgcaggaac
    22621 ggttgccagg tttactaagc attattctgg taggacttgt ttttgctttg actcatatgc
    22681 acagtttggc tctatcagag tggattggtg cagttggtta cttaggtgga ggccttgcct
    22741 tttctattat ttatgtgaaa gaaaaagaga atatctacta tcccctactt gttcacatgt
    22801 taagcaacag cctctcctta atcattttag ctatcagtat agtaaaatga aataagaaca
    22861 ggacaaatca atcaggacag tcaaatcgat ttctaacaat gttttagaag tagaggtgta
    22921 ctattctagt ttcaatacac tgtaacatgt gatgaaaatg ccagtaatga taccgagaaa
    22981 aaagctgaga aacttttccc agctttattt gttatagtca aagcgaatga cttgttcctg
    23041 tgcatctaca tgagcatgga ccccaaaggg tacaattgct cttggagttg cgtggccgac
    23101 attcagatta tagacaatcg ggatattgct gtcaatgata tccaatagtg cctctttata
    23161 gtcgtcatgg aaagtttcat ccataggttt tccgaccaag agtccattga tgaccgcgaa
    23221 tatgccagtg tcctttaaag ttagcaacat ctttttgaag tcttctggct taggcttttc
    23281 ttcgcttgtt tcgagcaaga ggattttccc ttcccagtct gacaagtcag ggaaaagttt
    23341 gtattttggg cagagttccg tgctatctgc gtatcgagag ttgtcaaaga tatcgtagag
    23401 ggattctagg caaccaccga ggattttccc ctcgaactga gcacttcctt gcaacaagtc
    23461 aaaacctgta tttgtatgac tgacacgagg tgttcccagg gccgtgggac taaaatcagt
    23521 tcgttcctca taccaaacgt cactagggcg gatttctgaa attcttcccg tctcaatcaa
    23581 ttctttaaag tagtgaaggc tataggctag catttctttg tctaattcac aaatgtctgc
    23641 taaaaaggat tgaccataaa aagtcttgat tcctaattta tgcaacatga ggtggttcat
    23701 ggttgtatcc gagaagccaa gaaaaatttt ttgcttgata accttttgga gttggtcatt
    23761 ttcaaaaaga taaggtagca agcgataggt atcgtctcca ccgatggcac ataggatcat
    23821 gtcgatgcta tcatcagaaa aggcatgaat caaatcctct gcacgagctt caggatggtc
    23881 cttgataaag tctaatcctt ttaacgaatg gggcaaaaag atgggattga gtcccagatc
    23941 cttgagacgt tggataccca agtccacttc gtgtttgaca aaatcctctc cgataatgcc
    24001 actagataaa ctaacaatac caatagtaga aaccatatct catcctccta gaaatagatt
    24061 gagcctattt tatcacaaaa tataagagaa agctatgtgg gatttcagaa gaatactttt
    24121 aatactcttc gaaaatctct tcaaaccacg tcagttttat ctgcaacctc aaagctgtgc
    24181 tttgagcaac ctgcagctag cttcctagtt tgctctttga ttttcattga atataactca
    24241 aaaaagtaag tgaaaaagca accgcacctg cagttgcttt tatcgttttc ttattcttga
    24301 tagcgtgttg gtcctgcact tgcactacgg atattcaagc gtttcttgag atagaagcga
    24361 agggctagga gggctgctcc aataatagct agtggcaatg gatccagtac tgggttaagg
    24421 ctagctggta ggaagcttgt tgcaaagaag acaagcaacc aaaggaacat agaagctagg
    24481 ataactagta cagatttcca gaaaggtgga cgttgactgc gatccatatc tggtccatag
    24541 tattggtaaa caaagtagta catcaagtag aaggcaaatc caccaaccag tccaactaat
    24601 agaagagtaa tcaatccata gccgaaagct tggtctgccg caaagaaggt tgtgagggcg
    24661 ctgacaaggg caaagaggct agtgatgaaa agagctgagt ccataatcat cagttttggg
    24721 tcatcatttt cttttggatg ctctttttcg tactgctctt tgacagtgaa gctatgagcc
    24781 caatgagttg gtgcgccgta tagggaacgg gcagttgtac ctttagattg ctcctcaagg
    24841 atttggggaa tgacttcctc aaaaatagtc tggatttcag cgtctgtttt cccatctttg
    24901 atgaattgtt gggtagcaat gtggacaaac tcttggtttt tcttagttaa tttttgtaga
    24961 tcaatttgag acataggaac tcctcttaga accatttttt atggatgaga tagagagtga
    25021 gcgagacact catagcaaag gcgataaaga cgattaacca gaaggcattt ggctctccgt
    25081 ttagggggat ttcattatcc ttaaagttca tcccgtaggc agaaaagacc atggttggga
    25141 tggacatgac gatggtcaca agggccaagg ttttcatgat gttgttctgg ttgttagaaa
    25201 tgatagaggc aaaggtctct gtcatagaat gcaagacgtt tccataaata tctgccatct
    25261 cgatggcctg ttgggtttca atcagggtgt cttcaagcag gtcttcgtcc tcaaggtatt
    25321 tcttgatatt gctggttgaa ctggtcaatt tcttaatcac gcgctcattt gttttgaggg
    25381 aggccttgaa atagacgata gttttttcca attccatgag ctcaatcaat tcttcattac
    25441 gagttgattg atgcagttga ctttcgattt gttcactctt gcggtcgatt gaacgaaggg
    25501 ctgttaggta aagctctgca ttgcgataaa gaatttgaaa gataaaacgt gaacgcatga
    25561 aggtatagaa attacgcaat cgacggttga taaagacatc aaggacaggt agtggttcca
    25621 aacacgtagt gataatggtt tcctcagtga tgataatacc aagcgggatg gttacgtagt
    25681 aggtgcggtt atttctttcc tccgtgaccg gcacgtctac gataatcagg gtatactcgt
    25741 cttcaatggt aatacgagac atttcttccg catcgagcgg tgctcgaagg tcggcaatat
    25801 caatatcgaa ggtgttggcg atttcgagtg attcattttg agtcggattg acgagattga
    25861 tccaagtacc cggttcaagc gtatcgatct ctttaaattc agttgttgta gagagaaaaa
    25921 cttgtttcat atcccttatc ctttctcatt tttcagattt tttcacactg tactattata
    25981 ctacaaaatc ggccttttgg gtaatagaat ctcacttttt ttggtataat ggtaagcaat
    26041 aatggactag aaagaacaaa gatgcaagat aaaattgtca ttcatggggc gcgtgcccat
    26101 aatttaaaaa atattgatgt ggagattccg cgagacaagt tggttgtcgt gactggcttg
    26161 tcaggttcag ggaagtccag tctggctttt gatactctct atgcggaggg acaacgtcgc
    26221 tatgtagaga gtttgtccgc ctacgctcgt cagttcttgg gaaatatgga aaaaccagat
    26281 gtagatgcca ttgatggtct cagcccagct atttccatcg accagaaaac gactagtaaa
    26341 aatcctcgct cgacggtggg aacgacgact gaaatcaatg actatctgcg tctcctctac
    26401 gcacgtgtgg ggacgcctta ctgtatcaac ggacatggag ctatcaatgc ttcttctgtg
    26461 gagcaaatcg ttgataaggt tttggagtta cctgaacgcc agcgcttgca gatcttggct
    26521 cctgtcatcc gcaagaaaaa aggccaacat aagagtgtta tcgagaaggt tcagaaagac
    26581 gggtatgttc gtgttcgtgt ggatggggaa gtctatgatg tgaccgaagt gccagagttg
    26641 tctaagagca agcaacacaa tatcgatgtc gtggttgacc gtattgttat caaggagggc
    26701 attcgtagtc gtctctttga ttccattgag gctgcccttc gtattgcaga aggttatgtc
    26761 attatcgaca ccatggacga ttcggagttg ctcttctctg agcattatgc ctgtccagtt
    26821 tgtggtttta ctgtcccaga gttagagcct cgtctcttct ctttcaatgc tccttttggc
    26881 tcttgtagtg agtgtgacgg cttgggcatc aagctggagg tggatactga tttggtagtg
    26941 ccagatgcca gcaaaacctt acatgaggga gcgctggcac cttggaatcc tatctcatcc
    27001 aactactatc caaacatgtt agagcaggcc atgaaagtct ttggagtggc tatggataag
    27061 ccttttgagg acctgtcaga agaagataag aacttgattc tctacggctc agatggtaag
    27121 gaattccatt tccattatga aaatgaattt ggtggtgtgc gcgatatcga cattccgttt
    27181 gagggagtta tcaataatat caaacgtcgt taccatgaaa ccaatagcga ttacactcgc
    27241 actcagatgc gtctctacat gaatgagctg acctgcggaa cctgtcaagg ctatcgtctc
    27301 aatgaccagg ccttgtctgt ccgtgtgggc ggccagcaag ggccacatat tggagaaatc
    27361 tcagacctgt ctatcgctga ccacttggac ttggtgagcc agttaacttt gtctgaaaat
    27421 gaagccatca ttgctcgtcc cattctcaag gaaatcaagg atcgtttgac cttccttaat
    27481 aatgtgggtc ttaactatct aaccctgtca cgttcagcag gaaccctttc aggtggggaa
    27541 agtcagcgca ttcgtttggc aacccagatt ggttccaacc tatcaggtgt cctctatatc
    27601 ctagacgagc cgtcaatcgg tcttcaccag agggacaatg accgcctgat tgccagtctg
    27661 aaaaagatgc gtgacttggg caatactctt atcgtggtgg aacacgacga agataccatg
    27721 cgtgaagctg attatctgat tgacgttggt cctggtgccg gtgtttttgg tggtgagatt
    27781 gttgcagcag gtacacctaa gcaagtggct cgcaacagca agtctatcac aggtcagtac
    27841 ttgtcaggca aacgtgtcat cccagtacca gaagagcgcc gtgtcggaaa tggtcgtttt
    27901 attgaagtga caggagcgcg tgagaacaac ttgcaaaatg tcacggctcg ctttccacta
    27961 ggaaaattta tcgcagtgac aggtgtgtcg ggttcaggga aatcgactct aatcaacagc
    28021 attctcaaaa aagccattgc ccagaagctc aaccgtaatt cagacaaacc tggtaagttt
    28081 aagactatta cagggattga gcatgtcgac cgtttgattg atattgacca gagccctatc
    28141 ggacggacgc cgagatctaa cccagctacc tatacaggag tttttgacga tatacgtgac
    28201 ctttttgctc agacaaatga agccaagatt cgaggctaca agaaggggcg cttcagtttc
    28261 aacgtcaagg gaggtcgctg tgaagcttgc tcaggtgacg ggattatcaa gattgagatg
    28321 cacttcttgc cagatgttta tgtggcttgt gaagtttgcc acggaacccg ctataacagt
    28381 gaaaccctag aagttcacta caaggaaaag aatatttcgc aggtcttgga tatgacggtc
    28441 aacgatgcgg tagaattttt ccaacacatt ccgaaaattc aacgcaaact ccagaccatc
    28501 aaggatgtag gtctaggcta tgtgaccttg ggacagccag ctaccaccct ttctggggga
    28561 gaagcccaac gtatgaagtt agctagcgaa ctccacaaac gctcgacagg aaaatctttc
    28621 tacattctgg atgagccgac gacagggctt catacagagg acattgctcg cctgctcaag
    28681 gttttagctc gctttgtaga cgacggcaat acagtcctcg tcatcgagca caatctggat
    28741 gttatcaaga cggcagacca tatcattgac ttgggacctg agggcggtgt cggtggtgga
    28801 accatcatcg taacaggaac tccagaagaa gtagctgcca acgaagccag ctatacagga
    28861 cactatttga aaggaaagtt acatcatgaa taaacgcgta caagcatttc tagctaaaat
    28921 gcaagaaaaa gaactagatg gtatcatcat caacaatctt aaaaacgtct attatttgac
    28981 tggtttttgg ggctcaaacg gaacagtctt tatcagccgt gaccgtcagg tcttagtgac
    29041 agactctcgc tatatcatcg cagctaagca agaaaccagt ggttttgaga ttgtggctga
    29101 tcgtgatgaa ttggctgtca ttgcaggaat tgttaaggac atgggcttga ctcgtatcgg
    29161 ttttgaagat gagatttcag tgtcttatta ccaccgtatg caggcagctt ttgcaggttt
    29221 ggacttgctt ccacaaactc agtttgtgga aggtcttcgt atgattaagg atgaggcaga
    29281 gattgcagcg attcgcaagg cttgttctat ctcagaccaa gctttccgcg atgcgcttga
    29341 ctttatcaaa ccaggaaaaa ctgaaattga gattgccaac ttccttgatt tccgcatgcg
    29401 tgagttggga gcatctggct tatcttttga tacgatccta gctagcggta tcaattcttc
    29461 taaaccccat gcccatccaa tgcacaaacc agtggagttg ggagaagcca ttaccatgga
    29521 cttcggctgt ctctatgacc actatgtcag tgatatgacc cggactatct atctagggca
    29581 tgttagcgat gagcaggcag agatttacaa tacggttcta aaagctaacc aagccttgat
    29641 tgaccaagct aaggcaggct taggtttccg tgactttgac aaaatccctc gtgatattat
    29701 cattgaggca ggttatggcg actactttac tcacggcatt ggccacggta ttggtctgga
    29761 tatccatgag gaaccctact ttagccagac ttctacagaa actattaaga caggtatggc
    29821 cttgaccgat gaaccaggta tctatatcga aggcaaatat ggcgttcgta tcgaggatga
    29881 tatcctgatt acagagacag gttgtgaatt attgacccta gctccaaaag agttgatagt
    29941 catttagttg tttgtcaaga aaaaagtacg aaaatgacga aaaaagtcaa aaaaaattaa
    30001 aaataggtcg caagtcggat gttttttatg gtataataga ctaaactgat agtaacatgt
    30061 agcgaaaggg gtaggtacat gattaaaatt tatacagtct caagttgtac tagctgtaaa
    30121 aaagcaaaaa cctggctcaa tgcccaccag ttaagttata aagaacaaaa ccttggtaaa
    30181 gaaggaatta cgagagaaga attactggat attctaacca aaacagataa cggaatagcc
    30241 agcatcgttt cgtctaaaaa tcgctatgcc aaagcccttg gagtggatat tgaagatttg
    30301 agtgtcaatg aagttctcaa tctgattatg gaaacaccga gaattttaaa gagcccaatc
    30361 cttgtagatg aaaaacgcct gcaagttggc tacaaggaag acgatattcg tgccttccta
    30421 ccacgctctg tccgtaatgt agaaaatgca gaagcacgtt tgcgtgcagc tctataaaca
    30481 tcaaggctgg gagcacttcc cagtcttatt ctattttaat ttcaaaaaga aagaagaaag
    30541 aaatgaaaaa aatagttctt gttagtctag ctttcctttt tgtcctggtt ggttgcggac
    30601 agaaaaaaga aactggacca gctacaaaaa cagaaaaaga tacgcttcag tcggcattgc
    30661 cagttattga aaatgctgag aagaatacag ttgtaactaa gactttggtc ttgcccaagt
    30721 cagatgatgg tagccagcag acacaaacaa ttacttacaa agacaagact tttttgagtc
    30781 taactatcca acaaaaacgt ccagtctctg atgagttgaa gacttatatt gaccaacatg
    30841 gagtggagga aactcaaaaa gctcttcttg aagcggagga gaaggataag tctatcattg
    30901 aagctcgtaa attggcaggt ttcaaacttg aaacaaaact attgagcgca acggaacttc
    30961 aaacaacgac tagttttgat tttcaagttc tggatgtcaa gaaggcttcc cagttggaac
    31021 atctgaagaa tattggtttg gaaaatcttt tgaaaaatga accaagcaac tatatttcag
    31081 atagattggc aaatggcgcg acagaacaat agaaaatcca aataaataga ctgcctgaat
    31141 tgtagaaggt aaggaattat gctataatgg tactattcta aggaaagagg gtgttagaat
    31201 gggatttact gaagaaacag tacgttttaa attggacgat tccaataaaa aagaaattag
    31261 cgaaactttg acagatgttt atgcttcgtt gaacgataag ggttacaacc caattaacca
    31321 aatcgtaggt tacgtattga gtggagaccc tgcctacgtt cctcgttata ataatgcacg
    31381 aaatcaaatc cgtaagtatg agcgtgatga aatcgttgag gaattggttc gctactacct
    31441 caaaggacaa ggagtcgatc tataacctat gagaattatg ggattggacg tcggttcaaa
    31501 aacggtaggg gtggcgatta gcgatccgct tggttttaca gctcaagggc ttgaaatcat
    31561 ccagataaat gaagaacaag gccaatttgg ttttgaccgc gttaaggaat tggttgatac
    31621 ttacaaggtg gaacgatttg tagtgggctt gcctaaaaac atgaacaata caagtggacc
    31681 gcgcgtagaa gctagtcaag cctacggagc aaagctagaa gagttttttg gtttaccagt
    31741 agactatcag gatgaacgct tgacaacagt ggctgctgag cgcatgttga ttgaacaagc
    31801 agatatcagt cgcaataagc gcaagaaagt cattgataag ttagcagctc agctgatttt
    31861 acaaaattat ttagatagaa aattttaata taaaggagag gctatgtcac acgatcataa
    31921 ccacgaccac gaagaacgtg aactaatcac actagtagat gagcaaggaa atgaaacctt
    31981 gtttgaaatc cttttgacaa ttgatggaaa agaagaattt ggtaaaaact atgttcttct
    32041 agtaccagtt aacgcagaag aagacgaaga cggacaagtt gaaatccaag cttactcatt
    32101 cattgaaaat gaagatggaa cagaaggcga attgcaacca atcccagaag actcagaaga
    32161 cgaatggaac atgattgaag aagtcttcaa cagctttatg gaggagtgat acagtctggg
    32221 agactgtatc agcccaactc ccagaaatgg ggaagagttg gaacgtccag tgaacatttt
    32281 taccccaact cttagaaatt gagaagagtt ggaacatcta gtggatgttt ttagcccata
    32341 ttcacattca tagtggctag ttattagcta accaggtaag aggtcgggac gaaaatcctg
    32401 gccttgtttt tattagtaac catactttaa tgcgataatt gattggactt ttgtcaagga
    32461 gatgtgtatg tttgaagtag aagaatggct ccatagtcgg attggtttaa attttcgatc
    32521 aggtttgggc cgaatgcagc aagcggtgga tttgttagga aatcctgagc agtcttaccc
    32581 tattatccac gtaacaggga ctaatgggaa aggatctacc attgctttta tgagggaatt
    32641 atttatgggg catggcaaaa aagttgcgac ctttacctcc cctcatatcg tctctatcaa
    32701 tgaccgaatc tgcattaatg ggcaacctat agcagacgca gactttatcc gtttggctga
    32761 tcaggtcaag gagatggaga aaacgcttct gcaaactcct gaccagttgt ccttttttga
    32821 attgctgacc ttggttgctt ttctttattt tagggagcaa gaggtggatt tggttttatt
    32881 agaagtggga attggtggct tacttgacac gaccaatgtg gtaactggag agcttgctgt
    32941 catcacctcc attgggcttg accatcaaga aaccttgggt gatagtctag aagcaattgc
    33001 agagcagaaa gctggtattt tcaaggctgg taagaaggca gtgattgcga aattgcatcc
    33061 agaagctagg cttgtctgtc agaaaaaagc cgaatcttta gctgttaacc tttatcaggc
    33121 aggtcaagat tttttaatgc tgaatggtga tttttcaagc tctttactaa atctttcaca
    33181 gctgaacata ggcttagaag gagtctatca gcaggagaat gcagccttgg cgttgcaaac
    33241 ttttcttctt tttatgggag aaggaaagga agctgttgat gaacaggctg taagaaaggc
    33301 cttggaacag acccattggg ctggtcgctt ggagcgtatt cgcccacaga tttacttgga
    33361 tggtgctcat aacctccctg ccttgactcg cttggttgag tttattaaag aaaaagagca
    33421 ggaaggttat cgtcctcaaa tcctctttgg atccttgaaa cggaaggatt atcaagggat
    33481 gttgggttat ctgactgaaa atttacctca agtggaactc aagatgactg gttttgacta
    33541 tcaagggtct ttggacgaaa gggatgtgac aggttacgat atagtttctt cttaccgaga
    33601 atttatcagc gattttgaag aaagagcaga tgctcaggat ttgctgttcg ttacagggtc
    33661 tctctatttt atctcagaag tacggggcta cctgctggat cgtgagcaga taaattgacc
    33721 cccttgtttg aacttgttat actagggaaa ttgctggtta gagaaaattt ctctaaattg
    33781 gtagcagaaa ggaaattcat catgaaatta aaaagattca cactttctct tgcttctcta
    33841 gcaagtttta gtctcttagt agcttgttca caaagagctc aacaggttca acagcctgct
    33901 caacaggtcc aacagcctgc tcaacagaat accaatactg caaatgcagg aggtaaccaa
    33961 aatcaagcgg ctccagtaca aaaccaacct gttgctcaac cgaccgatat tgatgggact
    34021 tatactggtc aggatgacgg agaccgtatc actttagtgg taactggaac gactggtaca
    34081 tggactgagc tcgaatctga cggggatcag aaagtcaaac aggttacatt tgattcagca
    34141 aatcaacgca tgattattgg cgatgatgtc aaaatttaca ctgtaaacgg taatcaaatc
    34201 gtcgtagatg atatggatag agacccatca gaccaaatcg ttttaactaa ataagactat
    34261 gcaagtagaa agggctggat ttttcagcct ttttactttt acctagaaaa taatcataaa
    34321 tacttgcctt ctaccgaata cctgcgttat actagtatca attacttgtt tttagcattc
    34381 aaactatcaa ggaggggata tgaaatatag gaaatttcaa ttattgatgt ccaagtatgg
    34441 ctttagtctt tcgattatgt tacttgaact ttgtcttgtt tttggtctct ttctttattt
    34501 aggacgcatg gctcccattt tatggattac tgtcctcatt ctactgagta tcatcacaat
    34561 catttcgata gtcaaccgta atacgactcc tgagaataag gtaacctggt tgttagtagc
    34621 ctttgtgcca gtatttggtc ccttgctcta tctgatgttt ggtgaaaggc gattgtccaa
    34681 aaaagaaatc aaacaactga agaagctagg ctctatgcat ttccaagaag caaatagcca
    34741 gctactaaaa gagaaattaa aagaaagtga caaggcagct tatggagtca tcaagtcctt
    34801 attgagtatg gataccaatg ctgacatcta tgatcaaact gcctctacat tttttcctaa
    34861 cggagaagct atgtggaaaa agatggtaga agatcttaaa aaggctgaga aatttatttt
    34921 cttggaatat tacattatag aagaaggttt gatgtggaat cgcatactag atatactaga
    34981 gcaaaaggta gctcagggtg tagaggttaa gatgctctat gatgatatcg gctgtatggc
    35041 tactttaaca ggagattatg cacatcgact tcgtcagctg ggcatcgagg cccataaatt
    35101 caataaagtt attcctcgtt tgacagtggc ttataataac agagatcata gaaaaatatt
    35161 gattgttgat ggtcagatag cctatactgg tggggtcaat ctggcagatg agtacattaa
    35221 ccacgtcgag agatttggtt attggaagga tagtggaatt cgcttagacg gactagcagt
    35281 aaaagccctg acacgcttat ttttgaccac ttggtacatt aatcgaggag aaattagtga
    35341 ttttgatcaa tatcatttag aaaatcattc tatcccgagt gacggtttaa ccattccata
    35401 cggaagtgga cccaagccaa tttttcgagc gcaggtaggg aaaaaagttt atcagagttt
    35461 aatcaatcaa gcaacggaat cggtctatat tacgacacct tatttgatta tagattatga
    35521 tttaacagag acaatcaaaa atgcagctat gagaggggtc gatgttcgaa ttatcacccc
    35581 ttacatacca gataagaagt tcattcagtt agtcacgaga ggagcttatc ccgaccttct
    35641 ttctgctggt gttcggattt atgagtatag tccaggtttt attcatagta agcagatgtt
    35701 ggtagacgaa gattttgcgg tggtggggac aatcaatctc gactaccgga gcttggtaca
    35761 ccattatgaa aatgcagtct tactctataa aactccttct ataagggaaa tcgcccgaga
    35821 ttttcgaaat atatttgcag attctcagga agtctatcct cattctatca aaacgagctg
    35881 gtatcaaaag cttgtaaaag aaatcgccca gctattcgcc cctatcttat aagaaatcta
    35941 gaacttagga tacaaaccag acctattttt cttgtctttt acgaatagaa agaaagagga
    36001 ggggaattca tgctaactaa ggaagaagtg aatgatatga ttgagttcaa acagacacat
    36061 ttacaccgct ttcgggaaat tgaaaccttt gtgaaactat gcaaaaaatc actcaaacag
    36121 ccatcgcaag ctgacaatcc taggactttt tgatatacta agacagataa attgaacagg
    36181 agaaacgata tgagtgtgta tggtagagta gaagaagttc ataaggagaa tcgtgaacct
    36241 ctagaatacc aaatcgaaca agaatcgcat catcgtgaat caagtcgtct tcctttggtg
    36301 aaaattttac tatggagtac gcttgtaacg gggataactc taggagtacc gctattactc
    36361 gacttaatga gtgcacaaga agtgcaggat ttttatgcag gttgggcgct tcatcagaca
    36421 gggaagattt acagcgacta ttatggaagt caaggtttgc tttattattt gctgacttac
    36481 gtgagtcagg gcggattttt ctttgccatc tttgagtggt tggccttggt agcaggagga
    36541 tttttccttt ttagatcagc ggacaccttg acagagcaag gagaccaagc tggacatctg
    36601 gtgactattt tttacatgct agttacaggt cttgcttttg gtggaggcta tgcgactctt
    36661 ttagcgcttc ctttcttatt cgcagccttt agtttagttg cggcttacct aagcaatcca
    36721 agccatgata agggatttgt acggattggg ctagctttgg caggcggatt tttctttgct
    36781 cccttatcat cgctcctgtt tattgctgta gtgagtttag gcttgttggt ctttaacctt
    36841 gggcatagac gttttgtgca tgggttttat cagtttcttg cagtggcttt aggtttttca
    36901 cttgtctttt atccaactgc ctactatagt gctgcaacag gaagttttgg ggatgcgatt
    36961 agtggtattc gttatcctat tgacagtatt cgctttgatt ttacttctaa aattttagag
    37021 aatatgtttt tttatggctt gttgtccctt ggtttgggat ttgtggtttg tatcttttta
    37081 ggtctctttc aatccaaacc ctttaaacta tacgtcattt cggttcctgc aagtcttgtg
    37141 gtaattttag gtttgatttt acttttcttt tcacaagagc ctctgcacgc ttcttatttg
    37201 atggtcgtct tccctgtttt cctactttta ttggtaacca atattaagag tcaacagagg
    37261 gggcgtagtg ctagaagaag ccgaagagaa acgccagtta gcctatggag tcgtttcttc
    37321 aaaggaaatc tatatctgct agtttttggg tttgtctatc ttttgtctgt tccttttttg
    37381 atgaagtttg tcctttatcc agtaccttat caagaacgta atcgtcttgc tgatttggta
    37441 aaagaggaga caaatacgga agatgctatc tatgcatggg atgatactgc gactctttat
    37501 cgtaagagtg agcgcttgtc gccatcggcg attttgtccc cgttgcacta tacagcaact
    37561 gaggaaaatc gtaataagtt acttaatgac ttgaaagaaa aacaacctaa ggtgattgtg
    37621 gtaaatgata aggtggtagt ctggtctgaa gtggaaacac tcttaaaaga aaattaccaa
    37681 caagtaaaga ctgattactc agagtttaaa gtctataaaa ttaaataacc aaatcaatat
    37741 cttgtgtatt tttaaaaatt ttaggatttt taacacaaga tattgatttt tctttttaga
    37801 gtggtataat actttttaga aagaacattt tagaaaagag catgcatatg attgcactag
    37861 aagaaaaaat tacaattttg ccaactctct tcgtcgagaa acgagatggg agacgtgttg
    37921 tatttgatgt ggacaagatt gacaaggctc tccacaaggc ggctgacaag gttatggatg
    37981 tgacacccct ggttgaaaaa cgcctcaatg atctgactga gcgaattatt acagaaattc
    38041 atagtcgctt tccacaggga attaagattt acgaaattca aaatatcgta gaacatgaac
    38101 tccttgaagc caaagaatat gcgctggctg aggagtatat tacttatcgg acacagaggg
    38161 attttgagcg ctcaaaagcg acggatatca actttagtat tcataaactt ctcaacaaag
    38221 accagacagt tgtcaatgaa aacgctaata aagacagtga tgtctttaac actcagcgtg
    38281 atttgacagc agggattgtt gggaaatcaa tcggactgca aatgcttcct aagcacgtag
    38341 ccaatgccca ccaaaagggg gatatccact atcacgattt ggactacagt ccctataccc
    38401 ctatgaccaa ctgctgtttg attgatttta agggtatgtt ggaaaatggt tttaagattg
    38461 gaaatgcaga ggtagagagt cccaagtcta tccagactgc gacagcacag atttctcaaa
    38521 tcattgccaa cgttgcttct agccagtacg gtggctgttc agctgaccgt atcgatgaaa
    38581 ttttggcgcc ttatgcagag aagaattatc aaaaacatct caaagatgca gaagagtggg
    38641 tattgcctga aaaacaggaa gattacgctt ggaagaaagc gcaaaaggac atctacgatg
    38701 ccatgcaatc tcttgagtat gaaatcaata ctctcttcac ttcaaatgga caaacacctt
    38761 ttacttcgtt aggttttggt ctgggaacca gtcgttttga acgagaaatt caaaaagcta
    38821 ttttaaacat tcgcatcaag ggtcttggtt cagaacaccg tacggctatc tttcctaaac
    38881 ttatctttac gcttaaaaga ggcctcaact tagaggaagg aactcccaac tatgacatca
    38941 agcagttggc tctagagtgt gcaaccaagc ggatgtatcc agacgtcttg tcttatgata
    39001 agattgttga tttgacaggt tctttcaagg tgcctatggg ctgccgttct ttccttcaag
    39061 ggtggaagga tgaaaatggt gtagaagtca attcaggtcg catgaatctg ggtgttgtga
    39121 cggttaatct gcctcgtatt gctcttgagt ctgaaggtga tatgaataag ttctgggaaa
    39181 tcttcaacga gcgaatgaat atcgcagaag atgctcttgt ttaccgtgtc gaacgcacta
    39241 aagaggcgac accagcgaat gctcctattc tttatcagta cggtgctttt ggccatcgtc
    39301 taggtaaaga agaaagtgtt gaccagctct ttaagaatcg tcgtgcgacc gtttcgctgg
    39361 gctatatcgg cttgtatgaa gtagcgacag ttttctttgg taacagctgg gaaagtaatc
    39421 cagatgctaa ggaattcacg ctagacatca ttcacgatat gaaacgccgt gtagaagagt
    39481 ggtcagacca atatggctac catttctcta tctactcaac accatccgaa agtctgacag
    39541 accgtttctg ccgactagat atagacaagt ttggctctat tcctgatatc acagacaagg
    39601 aatactacac caactctttc cactacgatg ttcgtaaaaa tccaacaccg tttgaaaaat
    39661 tggactttga gaaagtctat ccagaagcag gtgcgtcagg tggtttcatc cattattgtg
    39721 agtatccagt ccttcagcaa aatccaaagg ccttggaagc tgtctgggat tatgcttatg
    39781 accgtgtagg ctatctaggc accaatactc cgattgaccg ttgctacaag tgtgactttg
    39841 aaggggattt tgaaccaact gagagagggt ttgcttgtcc aaactgtggc aatagcgatc
    39901 ctaaaacagt agacgttgtt aaacggactt gtggctatct tggcaatcct caagcgagac
    39961 caatggttaa cgggcgtcac aaggaaatcg ctgcgcgtgt caaacatatg aatggttcaa
    40021 cgattaaaat agctgggcat caagtaacaa attagaaaga aatgaaatgg gaaaatatca
    40081 actagacgat aaggggcgcg cacaagtgac ccgttatcac gagaaacact ctaaaggtgg
    40141 agctggtaag aaagaacgct tgcttagctt cagagaacaa tttttaaaca agaacaagaa
    40201 aaaataaaag tgagagccag ctctcgcttt tctcatagtg ggaggtaggg atggaattac
    40261 gcagaccaag attagcagat aaagaaacag ttttagagat gatgacagag tttgaaaaat
    40321 ttcagtcgcc tcacgacggc ggtttctgga atacagagaa ctttgtgtat gaagactggt
    40381 tagaaagcaa tcaggaacag gaaatgggga ttaatctgcc tgaaggatgg gttcctgcaa
    40441 ttcagttagt ggttttttct gagaaaggtc aagcagttgg atttcttaat ctccggttgc
    40501 gcctcagtaa ctttctacta gaagaaggtg ggcacattgg ctactccatt cgtccatctg
    40561 aaagaggcaa gggttatgca aaagagactc tccgtcaggg cttgcaagtt gctaaggaaa
    40621 agaacatcaa gaaagctctg gtgacctgta gcgtgaataa tcctgctagc agagcagtca
    40681 ttctagcaaa tgatggaata tttgaggatg ctcgcaatgg agtcgagcgt tattggatag
    40741 aggtagcgaa tgaataatcc aaaaccacaa gaatggaaaa gcgaggaact tagtcaaggt
    40801 cgtatcattg actacaaggc ctttaacttt gtggacggag aaggcgtgcg caactctctc
    40861 tatgtagcag gttgcatgtt tcactgcgag gggtgttata atgtagcgac ctggtccttc
    40921 aatgcaggca ttccctatac agcagaatta gaagagcaga tcatggcaga tcttgctcag
    40981 ccctatgttc aaggtttgac tttgttggga ggggagcctt ttcttaatac tgggattctc
    41041 ttgccacttg ttaagcggat tcggaaggaa ttgccagaca aggacatctg gtcctggacg
    41101 ggctacactt gggaagaaat gatgttggaa actccagata aactggaact cttatcactg
    41161 attgacattc ttgtcgatgg aagatatgat cgaactaaga gaaatcttat gctccagttt
    41221 cgaggttcgt ctaaccaacg aattatcgat gtgcaaaaat cgctcaaaag tgggcaagta
    41281 gtgatttggg acaagctcaa tgacggaaaa gaaagctatg aacaggtgaa gagagaatga
    41341 agaaaaaaga cttagtagac caactagtct cagagatcga gacggggaaa gtcaggacac
    41401 tgggaatata cggtcatgga gcttcaggta aatcaacctt tgcacaggaa ttgtaccaag
    41461 ctttagattc tactacagta aatttgctag agacagatcc ctatatcacc tcaggacgcc
    41521 atctggtagt acccaaggac gcgccgaatc aaaaggtgac agccagtctg ccagtggcgc
    41581 atgaactgga gagtttgcag agagatatcc ttgccttgca ggcgggtatg gatgtcttga
    41641 caattgaaga accttggaag gctagtgagg tcttgtctgg agccaaacca attttgattg
    41701 tcgaagggat gtctgttggt tttctaccca aggaactctt tgaaaaaacc atctgtttct
    41761 acacggatga ggagaccgaa ttaaagcgac gccttgctag agatacgact gtgagaaatc
    41821 gcgatgcatc ctttatattg gctagccatc agatgagacg ggagcagtat ctgcgatact
    41881 ataaagaaac tgagtctaag gcggatatct tagtggacca atcagaagat aaatttgatg
    41941 tcaagaggac ttaacttatg tatagaagaa atatagaaga aaatccctaa ttttagaaag
    42001 aaaaagtagg aaaacagttt catcccaaaa aaacgaaaaa acctaacaaa tcccttgcaa
    42061 tcgcagggga tttgtgttat tctattatgg tgctgtaaat tacagcctta gttttgatgc
    42121 aagaggttgc gacacgctcg gttgcattgc cacgcaacac cgcgtcggtt ttcttgtgga
    42181 gctagcctat tatcttaaat agacgaaaag gagaaaaaga tggcaaacaa aaaaatccgt
    42241 atccgtttga aagcttacga acaccgtacg cttgacacag cggctgcaaa aatcgtagaa
    42301 tcagctactc gtacaggtgc acaagttgcg ggtccaatcc cacttccaac tgaacgtagc
    42361 ctctacacaa tcattcgtgc gactcacaaa tacaaagact ctcgcgaaca atttgaaatg
    42421 cgtacacaca aacgtttgat cgatatcgtt aacccaactc aaaaaacagt tgatgccttg
    42481 atgaaattgg atcttccaag tggtgtaaac gtagaaatca aactttaatc taaaatataa
    42541 aagagcagag gctggtgttt caatctaatt gaacacgggc taaactcggt gtgaaaaaga
    42601 taaacttcct cgcgtctgct agacactgtg tcagtttcct attttcacgt tgagtttgac
    42661 gccctttgta tcttagactt gagcataaaa aacgctcgtt aaaaactttt tgaataaaaa
    42721 tatagaaaag gaactatttt ctcatgacaa aaggaatctt agggaaaaaa gtgggaatga
    42781 ctcaaatctt cactgaagct ggcgaattga tccctgtaac agttattgaa gcaactccaa
    42841 acgttgttct tcaagttaaa actgttgaaa cagacggata caacgctatc caagttggtt
    42901 tcgatgacaa acgcgaagta ttgagcaaca aacctgctaa aggacatgta gcgaaagcta
    42961 acacggctcc taagcgcttc attcgtgaat tcaaaaacgt tgaaggcttg gaagttggtg
    43021 ctgaaattac agttgaaaca ttcgcagctg gagacgttgt tgacgtaact ggtacttcta
    43081 aaggtaaagg tttccaaggt gttatcaaac gccacggaca atcacgtgga ccaatggctc
    43141 acggttctcg ttaccaccgt cgtccaggtt ctatgggacc tgttgcacct aaccgcgtat
    43201 tcaaaggtaa aaaccttgca ggacgtatgg gtggtgaccg cgtaacaatt caaaatcttg
    43261 aagttgtaca agttgttcca gaaaagaacg ttatccttat caaaggtaac gtaccaggtg
    43321 ctaagaaatc tcttatcact atcaaatcag cagttaaagc tggtaaataa taaagaaagg
    43381 ggaaatcagt cacaatggca aacgtaacat tatttgacca aactggtaaa gaagctggcc
    43441 aagttgttct tagcgatgca gtatttggta tcgaaccaaa tgaatcagtt gtgtttgatg
    43501 taatcatcag ccaacgcgca agccttcgtc aaggaacaca cgctgttaaa aaccgctctg
    43561 cagtatcagg tggtggacgc aaaccatggc gtcaaaaagg aactggacgt gctcgtcaag
    43621 gttctatccg ctcaccacaa tggcgtggtg gtggtgttgt cttcggacca actccacgtt
    43681 catacggcta caaacttcca caaaaagttc gtcgcctagc tcttaaatca gtttactctg
    43741 aaaaagttgc tgaaaacaaa ttcgtagctg tagacgctct ttcatttaca gctccaaaaa
    43801 ctgctgaatt tgcaaaagtt cttgcagcat tgagcatcga ttctaaagtt cttgttatcc
    43861 ttgaagaagg aaatgaattc gcagctcttt cagctcgtaa ccttccaaac gtgaaagttg
    43921 caactgctac aactgcaagt gttcttgaca tcgcaaatag cgacaaactt cttgtcacac
    43981 aagcagctat ctctaaaatc gaggaggttc ttgcataatg aatttgtatg atgttatcaa
    44041 aaaacctgtc atcactgaaa gctcaatggc tcaacttgaa gcagggaaat atgtatttga
    44101 agttgacact cgtgcacaca aacttttgat caagcaagct gttgaagctg ctttcgaagg
    44161 tgttaaagtt gccaatgtta acacaatcaa cgtaaaacca aaagctaaac gtgttggacg
    44221 ttacactggt tttactaaca aaactaaaaa agctatcatc acacttacag ctgattctaa
    44281 agcaatcgag ttgtttgctg ctgaagctga ataatctaag gaggaaatat cgtgggaatt
    44341 cgtgtttata aaccaacaac aaacggtcgc cgtaatatga cttctttgga tttcgctgaa
    44401 atcacaacaa gcactcctga aaaatcattg cttgttgcat tgaagagcaa ggctggtcgt
    44461 aacaacaacg gtcgtatcac agttcgtcac caaggtggtg gacacaaacg tttctaccgt
    44521 ttggttgact tcaaacgtaa taaagacaac gttgaagcag ttgttaaaac aatcgagtac
    44581 gatccaaacc gttctgcaaa catcgctctt gtacactaca ctgacggtgt gaaagcatac
    44641 atcatcgctc caaaaggtct tgaagtaggt caacgtatcg tttcaggtcc agaagcagat
    44701 atcaaagtcg gaaacgctct tccacttgct aacatcccag ttggtacttt gattcacaac
    44761 atcgagttga aaccaggtcg tggtggtgaa ttggtacgtg ctgctggtgc atctgctcaa
    44821 gtattgggtt ctgaaggtaa atacgttctt gttcgtcttc aatcaggtga agttcgtatg
    44881 attcttggaa cttgccgtgc tacagttggt gttgtcggaa acgaacaaca tggacttgta
    44941 aaccttggta aagcaggacg tagccgttgg aaaggtatcc gcccaacagt tcgtggttct
    45001 gtaatgaacc ctaacgatca cccacacggt ggtggtgaag gtaaggcacc agttggtcgt
    45061 aaagcaccat ctactccatg gggcaaacct gctcttggtc ttaaaactcg taacaagaaa
    45121 gcgaaatctg acaaacttat cgttcgtcgt cgcaacgaga aataatatta aactagtcgc
    45181 ttaagcaact agtaaatccg ccagctcggt agcgctccat aggagtgcaa gccgctgtgg
    45241 tacaacattt aaaggagaaa atataaaaat gggacgcagt cttaaaaaag gacctttcgt
    45301 cgatgagcat ttgatgaaaa aagttgaagc tcaagctaac gacgaaaaga aaaaagttat
    45361 taaaacttgg tcacgtcgat caacgatctt cccaagtttc attggttaca ctattgcagt
    45421 ttatgacgga cgtaaacacg tacctgttta catccaagaa gacatggtag gccacaaact
    45481 tggtgaattt gcaccaactc gtacttacaa aggtcacgct gcagacgaca agaaaacacg
    45541 tagaaaataa ggagaacata aatggcagaa attacttcag ctaaagcaat ggctcgtaca
    45601 gtacgtgttt cacctcgtaa atcacgtctt gttcttgata acatccgtgg taaaagcgta
    45661 gccgatgcaa tcgcaatctt gacattcact ccaaacaaag ctgctgaaat catcttgaaa
    45721 gttttgaact cagctgtagc taacgctgaa aacaactttg gtttggataa agctaacttg
    45781 gtagtatctg aagcattcgc aaacgaagga ccaactatga aacgtttccg tccacgtgcg
    45841 aaaggttcag cttcaccaat caacaaacgt acagctcaca tcactgtagc tgttgcagaa
    45901 aaataaggag gtaaaatcgt gggtcaaaaa gtacatccaa ttggtatgcg tgtcggcatc
    45961 atccgtgatt gggatgccaa atggtatgct gaaaaagaat acgcggatta ccttcatgaa
    46021 gatcttgcaa tccgtaaatt cgttcaaaaa gaacttgctg acgcagcagt ttcaactatt
    46081 gaaatcgaac gcgcagtaaa caaagttaac gtttcacttc acactgctaa accaggtatg
    46141 gttatcggta aaggtggtgc taacgttgat gcactccgtg caaaacttaa caaattgact
    46201 ggaaaacaag tacacatcaa catcatcgaa atcaaacaac ctgatttgga tgctcacctt
    46261 gtaggtgaag gaattgctcg tcaattggag caacgtgttg ctttccgtcg tgcacaaaaa
    46321 caagcaatcc aacgtgcaat gcgtgctgga gctaaaggaa tcaaaactca agtatcaggt
    46381 cgtttgaacg gtgcagatat cgcccgtgct gaaggatact ctgaaggaac tgttccgctt
    46441 cacacacttc gtgcagatat cgattacgct tgggaagaag cagatactac atacggtaaa
    46501 cttggtgtta aagtatggat ctaccgtggt gaagttcttc cagctcgtaa aaacactaaa
    46561 ggaggtaaat aaccaatgtt agtacctaaa cgtgttaaac accgtcgtga attccgtgga
    46621 aaaatgcgcg gtgaagcaaa aggtggaaaa gaagtagcat tcggtgaata cggtcttcaa
    46681 gctacaacta gccactggat cactaaccgc caaatcgaag ctgctcgtat cgccatgact
    46741 cgttacatga aacgtggtgg taaagtttgg attaaaatct tcccacacaa atcatacact
    46801 gctaaagcta tcggtgtgcg tatgggatct ggtaaagggg cacctgaagg ttgggtagca
    46861 ccagttaaac gtggtaaagt gatgttcgaa atcgctggtg tatctgaaga gattgcacgt
    46921 gaagcgcttc gacttgctag ccacaaattg ccagttaaat gtaaattcgt aaaacgtgaa
    46981 gcagaataag gagaaggcat gaaacttaat gaagtaaaag aatttgttaa agaacttcgt
    47041 ggtctttctc aagaagaact cgcgaagcgc gaaaacgaat tgaaaaaaga attgtttgaa
    47101 cttcgtttcc aagctgctac tggtcaattg gaacaaacag ctcgcttgaa agaagttaaa
    47161 aaacaaatcg ctcgtatcaa aacagttcaa tctgaagcga aataatagac tagggaagga
    47221 gaaatttcaa tggaacgcaa taatcgtaaa gttcttgttg gacgtgttgt atctgacaaa
    47281 atggacaaga caatcacagt tgtagttgaa acaaaacgta accacccagt ctatggtaaa
    47341 cgtattaact actctaaaaa atacaaagct catgatgaaa acaatgttgc caaagaaggc
    47401 gatatcgtac gtatcatgga aactcgcccg ctttcagcta caaaacgttt ccgtcttgta
    47461 gaagttgttg aagaagcggt catcatctaa tcaaacctga aaggagaaaa ctgaaatgat
    47521 tcaaacagaa actcgtttga aagtcgcaga caacagcggt gctcgcgaaa tcttgactat
    47581 caaagttctt ggtggttcag gacgtaaatt tgcaaacatc ggtgatgtta tcgtggcatc
    47641 tgtaaaacaa gctactcctg gtggtgcggt taaaaaaggt gacgttgtta aagcagttat
    47701 cgttcgtact aaatcaggtg ctcgtcgtgc tgatggttca tacatcaaat ttgacgaaaa
    47761 cgcagcagtt atcatccgtg aagacaaaac tcctcgcgga acacgtatct ttggcccagt
    47821 tgcacgtgaa ttgcgtgaag gtggcttcat gaagatcgtg tcacttgctc cagaagtact
    47881 ttaattttta ggaacaaact agtcccctag cttcaagcta gggtgccctt atgggcgtaa
    47941 gaaaaatcaa ggagaaacct aatgtttgta aaaaaaggcg acaaagttcg cgtaatcgct
    48001 ggtaaagata agggaacaga agctgttgtc cttactgccc ttccaaaagt aaacaaagtt
    48061 atcgttgaag gtgttaacat tgttaagaaa caccaacgtc caactaacga gcttcctcaa
    48121 ggtggtatca tcgagaaaga agcagctatc cacgtatcaa acgttcaagt tttggacaaa
    48181 aatggtgtag ctggtcgtgt tggatacaaa tttgtagacg gtaaaaaagt tcgctacaac
    48241 aaaaaatcag gcgaagtgct tgattaatca cgaaggaaag gagaagtata atggcaaatc
    48301 gtttaaaaga aaaatatctt aatgaagtag ttcctgcttt gacagaacaa ttcaactact
    48361 catcagtgat ggctgtgcct aaagtagata agattgtttt gaacatgggt gttggtgaag
    48421 ctgtatcaaa cgctaaaagc cttgaaaaag ctgctgaaga attggcactt atctcaggtc
    48481 aaaaaccact tatcactaaa gctaaaaaat caatcgccgg cttccgtctt cgtgaaggtg
    48541 ttgcgatcgg tgcaaaagtt acccttcgtg gtgaacgtat gtacgaattc ttggataaat
    48601 tggtatcagt ttcacttccg cgtgtacgtg acttccacgg tgttccaaca aaatcatttg
    48661 atggacgcgg gaactacaca cttggtgtga aagaacaatt aatcttccca gaaatcaact
    48721 tcgatgacgt tgacaaaact cgtggtcttg acatcgttat cgtaacaact gctaacactg
    48781 acgaagagtc acgtgcattg cttacaggcc ttggaatgcc ttttgcaaaa taatatagga
    48841 ggtaaatcta atggctaaaa aatcaatggt agctagagag gctaaacgcc aaaaaattgt
    48901 tgaccgttat gctgaaaaac gtgctgcatt aaaggcggca ggggactacg aaggtttatc
    48961 taaattacct cgcaacgcct caccgactcg tttacataat cgttgtagag ttacggggcg
    49021 cccacattca gtttaccgca aatttggtct gagtcgtatc gcttttcgcg aacttgcgca
    49081 taaaggtcaa attcctggtg taacaaaagc atcttggtaa tttaagatat caagagtgtc
    49141 aaaactccaa gtaaaaatag gaaacttgac gaagaaacta aagtttctag gaaagtttat
    49201 ctttttcaca cagagtttag cccgggttca attgggcttg ccaatttgaa cacgagctac
    49261 agctttggca aaaaagacca atttgctttg gagcattgct tctgcattaa attgtctatt
    49321 tttgctcgtg ctgttacgct ctttgtatca tgtattaact agcaagtgca acttgcaaac
    49381 tactagtaag aggagaaaaa caaaatggtt atgactgacc caatcgcaga cttcctaact
    49441 cgtattcgta atgctaacca agctaaacac gaagtacttg aagtacctgc atcaaacatc
    49501 aaaaaaggga ttgctgaaat ccttaaacgc gaaggttttg taaaaaacgt tgaaatcatt
    49561 gaagatgaca aacaaggcgt catccgtgta tttcttaaat acggaccaaa tggtgagaaa
    49621 gttatcacta acttgaaacg tgtttctaaa ccaggacttc gtgtctacaa aaaacgtgaa
    49681 gaccttccaa aagttcttaa cggacttgga attgccatcc tttcaacttc tgaaggtttg
    49741 cttactgata aagaagcacg ccaaaagaat gttggtggtg aggttatcgc ttacgtttgg
    49801 taaaatcaag atacaaagct cgtaaagaac aaagcaaaat taggaagttg gagaagtttg
    49861 tttacaaaca agccaactta tctattttgc acagttctta gagcgtgttc agttcagctc
    49921 ttgaactaaa taagtatctg aaccccgtga aaactggccg ttctggcctg acaatttaac
    49981 aggagaaaat aaacatgtca cgtattggta ataaagttat cgtgttgcct gctggtgttg
    50041 aactcgctaa caatgacaac gttgtaactg taaaaggacc taaaggagaa cttactcgtg
    50101 agttctcaaa agatattgaa atccgtgtgg aaggtactga aataactctt caccgtccaa
    50161 acgattcaaa agaaatgaaa actatccacg gaactactcg tgcccttttg aacaacatgg
    50221 ttgttggtgt atcagaagga ttcaagaaag aacttgaaat gcgtggggtt ggttaccgtg
    50281 cacagcttca aggatctaaa cttgttttgg ctgttggtaa atctcatcca gacgaagttg
    50341 aagctccaga aggaattact tttgaacttc caaacccaac aacaatcgtt gttagcggaa
    50401 tttcaaaaga agtagttggt caaacagctg cttacgtacg tagccttcgt tcaccagaac
    50461 catataaagg taaaggtatc cgttacgttg gtgaattcgt tcgccgtaaa gaaggtaaaa
    50521 caggtaaata atgttgagtg gttgatcatc aaccaccaac ctattttcca actttgtgca
    50581 tagcacacga tttaaaacta aagaggtgaa aactgtgatt tcaaaaccag ataaaaacaa
    50641 actccgccaa aaacgccacc gtcgcgttcg cggaaaactc tctggaactg ctgatcgccc
    50701 acgtttgaac gtattccgtt ctaatacagg catctacgct caagtgattg atgacgtagc
    50761 gggtgtaacg ctcgcaagtg cttcaactct tgataaagaa gtttcaaaag gaactaaaac
    50821 tgaacaagcc gttgctgtcg gtaaactcgt tgcagaacgt gcaaacgcta aaggtatttc
    50881 agaagtggtg ttcgaccgcg gtggatatct atatcacgga cgtgtgaaag ctttggctga
    50941 tgcagctcgt gaaaacggat tgaaattcta ataggaggac actagaaaat ggcatttaaa
    51001 gacaatgcag ttgaattaga agaacgcgta gttgctgtca accgtgttac aaaagttgtt
    51061 aaaggtggac gtcgtcttcg tttcgcagct cttgttgttg ttggtgacca caatggtcgc
    51121 gtaggatttg gtactggtaa agctcaagaa gttccagaag caatccgtaa agcagtagat
    51181 gatgctaaga aaaacttgat cgaagttcct atggttggaa caacaatccc acacgaagtt
    51241 ctttcagaat tcggtggagc taaagtattg ttgaaacctg ctgtagaagg ttctggagtt
    51301 gccgctggtg gtgcagttcg tgccgttgtg gaattggcag gtgtggcaga tattacatct
    51361 aaatcacttg gttctaacac tccaatcaac attgttcgtg caactgttga aggtttgaaa
    51421 caattgaaac gcgctgaaga aattgctgcc cttcgtggta tttcagtttc tgatttggca
    51481 taagaaaggg gataaaatgg ctcaaattaa aattactttg actaagtctc caatcggacg
    51541 cattccatca caacgtaaaa ctgttgtagc acttggactt ggcaaattga acagctctgt
    51601 tattaaagaa gataacgctg ctatccgtgg tatgatcaca gcagtatctc acttagtaac
    51661 agttgaagaa gtaaactaat gaagttttag gggatgtgca ctgtaccatc ccctaaaact
    51721 agatatagtc atctatgatg acatcgtata ggcgagttga tgggggagac aaccttttct
    51781 cccttatcgg cgctagcatt ttacaaaaga ggagaaaata aaaatgaaac ttcatgaatt
    51841 gaaacctgca gaaggttctc gtaaagtacg taaccgcgtt ggtcgtggta cttcatcagg
    51901 taacggtaaa acatctggtc gtggtcaaaa aggtcaaaaa gctcgtagcg gtggcggagt
    51961 tcgccttggt tttgaaggtg gacaaactcc attgttccgt cgtcttccaa aacgtggatt
    52021 cactaacatc aacgctaaag aatacgcaat tgtgaacctt gaccaattga acgtctttga
    52081 agatggtgct gaagtaactc cagttgttct tatcgaagca ggaattgtta aagctgaaaa
    52141 gtcaggtatt aaaattcttg gtaacggtga gttgactaag aaattgactg tgaaagcagc
    52201 taaattctct aaatcagctg aagaagctat cactgctaaa ggtggttcag tagaagtcat
    52261 ctaagagagg tgacctatgt tttttaaatt attaagagaa gctcttaaag tcaagcaggt
    52321 tcgatcaaaa attttattta caatttttat cgttttggtc tttcgtatcg gaactagcat
    52381 tacagttcct ggtgtgaatg ccaatagctt gaatgcttta agtggattat ccttcttaaa
    52441 catgttgagc ttggtgtcgg ggaatgccct aaaaaacttt tcgatttttg ccctaggagt
    52501 tagtccctat atcaccgctt ctattgttgt ccaactcttg caaatggata ttttacccaa
    52561 gtttgtagag tggggtaaac aaggggaagt aggtcgaaga aaattgaatc aagctactcg
    52621 ttatattgct ctagttctcg cttttgtgca atctatcggg attacagctg gttttaatac
    52681 cttggctgga gctcaattga ttaaaactgc tttaactcca caagtttttc tgacgattgg
    52741 tatcatctta acagctggta gtatgattgt cacttggttg ggtgagcaaa ttacagataa
    52801 gggatacgga aacggtgttt ccatgattat ctttgccggg attgtttcct caattccaga
    52861 gatgattcag ggcatctatg tggactactt tgtgaacgtc ccaagtagcc gtatcacttc
    52921 atctatcatt ttcgtaatca ttttgattat tactgtattg ttgattattt actttacaac
    52981 ttatgttcaa caagcagaat acaaaattcc aatccaatat actaaggttg cacaaggtgc
    53041 tccatctagc tcttaccttc cgttaaaggt aaaccctgct ggagttatcc ctgttatctt
    53101 tgccagttcg attactgcag cgcctgcggc tattcttcag tttttgagtg ccacaggtca
    53161 tgattgggct tgggtaaggg tagcacaaga gatgttggca actacttctc caactggtat
    53221 tgccatgtat gctttgttga ttattctctt tacattcttc tatacgtttg tacagattaa
    53281 tcctgaaaaa gcagcagaga gcctacaaaa gagtggtgcc tatatccatg gagttcgtcc
    53341 tggtaaaggt acagaagaat atatgtctaa acttcttcgt cgtcttgcaa ctgttggttc
    53401 cctcttcctt ggtgtgattt ccattttacc gattgcagct aaagatgtat ttggtctttc
    53461 tgatgttgtt gcctttggtg gaacaagtct cttgatcatt atctctacag gtatcgaagg
    53521 aatcaagcaa ttggaaggtt acctattgaa acgtaagtat gttggtttca tggacagaac
    53581 agaataaaag tatttactga atcagtaaat gctgagggag tggaggttta aactctgaca
    53641 tttgtaagag ttggatctcc cctcttctat tttgttttta aataggggtg aaaagacttt
    53701 ttgcttctat ttaaaaataa aataaggaga tcaaatcatg aatcttttga ttatgggctt
    53761 acctggtgca ggtaagggaa ctcaagcagc aaaaatcgta gaacaattcc atgttgcaca
    53821 tatctcaaca ggtgatatgt tccgcgctgc aatggcaaat caaactgaaa tgggtgttct
    53881 tgctaagtca tatattgaca agggtgaatt ggttcctgac gaagttacaa atggaatcgt
    53941 aaaagaacgc ctttcacaag atgatattaa agaaacagga ttcttattgg atggttaccc
    54001 acgtacaatt gaacaagctc atgccttgga caaaacattg gctgaacttg gcattgaact
    54061 agaaggtgtt atcaatattg aagtgaaccc tgacagcctc ttggaacgtt tgagtggccg
    54121 tatcatccac cgcgtaactg gagaaacttt ccacaaggtc tttaacccac cagttgacta
    54181 taaagaagaa gattactacc aacgtgaaga tgataagcct gagacagtaa aacgtcgttt
    54241 ggatgttaat attgctcaag gagaaccaat cattgctcac taccgtgcca aaggtttggt
    54301 tcatgacatc gaaggtaatc aagatatcaa tgatgtcttt tcagatattg aaaaagtatt
    54361 gacaaatttg aaataaagcg tttttcatac ttgcaaaaat tcgctacaaa tgttatactg
    54421 agatagtctg acttataatt gttgtctctg tgtctagagg catcgaatcg aaatttatgg
    54481 aggtgctttt gcgtggcaaa agacgatgtg attgaagttg aaggcaaagt agttgataca
    54541 atgccgaatg caatgtttac ggttgaactt gaaaatggac atcagatttt agcaacagtt
    54601 tctggtaaaa ttcgtaaaaa ctatattcgt attttagcgg gagatcgtgt tactgtcgaa
    54661 atgagtccat atgacttgac acgtggacgt atcacttacc gctttaaata atcgaaaaac
    54721 ttggagggat aagaaatgaa agtaagacca tcggtcaaac caatttgcga atactgtaaa
    54781 gttattcgtc gtaatggtcg tgttatggta atttgcccag caaatccaaa acacaaacaa
    54841 cgtcaaggat aagatagaaa ggagaaaaca tggctcgtat tgctggagtt gatattccaa
    54901 atgacaaacg cgtagtaatc tcattgactt atgtttatgg tatcggactt gcaacatcta
    54961 agaaaatttt ggctgctgct ggaatctcag aagatgttcg tgtacgtgat cttacatcag
    55021 atcaagaaga tgctatccgt cgtgaagtgg atgcaatcaa agttgaaggt gaccttcgtc
    55081 gtgaagtaaa cttgaacatc aaacgtttga tggaaatcgg ttcataccgt ggtatccgtc
    55141 accgtcgtgg acttcctgtc cgtggacaaa acactaaaaa caacgctcgc actcgtaaag
    55201 gtaaagctgt tgcgattgct ggtaagaaaa aataatatag gaggtaaaag tcttggctaa
    55261 accaacacgt aaacgtcgtg tgaaaaagaa tatcgaatct ggtattgctc atattcacgc
    55321 tacatttaat aacactattg ttatgattac tgatgtgcat ggtaatgcaa ttgcttggtc
    55381 atcagctggt gctcttggtt tcaaaggttc tcgtaaatct acaccattcg ctgctcaaat
    55441 ggcttctgaa gctgctgcta aatctgcaca agaacacggt cttaaatcag ttgaagttac
    55501 tgtaaaaggt ccaggttctg gtcgtgagtc agctattcgt gcgcttgctg ccgctggtct
    55561 tgaagtaaca gcaattcgtg atgtgactcc agtgccacac aatggtgctc gtcctccaaa
    55621 acgtcgccgt gtataatcat cgcattacac tgcttttcgt ttaagaggga gtaactaaat
    55681 gatcgagttt gaaaaaccaa atataacaaa aattgatgaa aataaagatt atggcaagtt
    55741 tgtaatcgaa ccacttgaac gtggctacgg tacaactctt ggtaactctc ttcgtcgtgt
    55801 acttctagct tctctaccag gagcagctgt gacatctatc aacattgatg gtgtgttaca
    55861 tgagtttgac acagttccag gtgttcgtga agacgtgatg caaatcattc tgaacattaa
    55921 aggaattgca gtgaaatcgt acgttgaaga cgaaaaaatc atcgaactgg atgttgaagg
    55981 tcctgctgaa gtaacagctg gtgacatttt gacagatagc gatattgaaa ttgtaaatcc
    56041 agatcattat ctctttacaa tcggtgaagg ttcttctcta aaagcgacta tgactgttaa
    56101 cagtggtcgt ggatatgtac ctgctgatga aaataaaaag gataatgcac cagttggaac
    56161 acttgctgta gattctattt atacaccagt tacaaaagtc aactatcaag tggaacctgc
    56221 tcgtgtaggt agcaatgatg gtttcgacaa attaaccctt gaaatcttga caaatggaac
    56281 aattattcca gaagatgctt tagggctttc agcacgtatt ttgacagaac atcttgattt
    56341 gtttacaaat cttactgaga ttgctaagtc aactgaagtg atgaaagaag ctgatactga
    56401 atctgacgac cgtattttag atcgtacgat tgaggaactg gacttgtctg tgcgttcata
    56461 caactgttta aaacgtgccg gtatcaatac tgtgcatgat ttgacagaaa aatctgaagc
    56521 agagatgatg aaagtacgaa atcttggacg caagagtttg gaagaagtga aactcaaact
    56581 cattgatttg ggtcttggat taaaagataa ataaaggagg aatacatggc ttaccgtaaa
    56641 ctaggacgca ctagctcaca acgtaaagca atgcttcgcg atttgacaac tgaccttttg
    56701 atcaacgaat caatcgtgac aactgaagct cgtgctaaag aaatccgtaa aactgttgaa
    56761 aaaatgatta ctctaggtaa acgtggtgat ttgcatgcac gtcgtcaagc agctgctttc
    56821 gtacgtaatg aaatcgcatc tgaaaactat gatgaagcaa ctgataagta cacttctact
    56881 acagcacttc aaaaattgtt ctcagaaatc gcacctcgtt atgctgaacg taacggtgga
    56941 tacactcgta tccttaaaac tgaaccacgt cgtggtgatg cagcgccaat ggcgatcatc
    57001 gaattagtat aaaatcatca attttgttga gtgttatgat gatggagtct tgtgctctta
    57061 gtctagctct ggtctaccgc taggatttcg gtcctagcgg gaacactcat cataagttgg
    57121 gatagtagac gcttgtttac gaaattgttt ttttcttaag aacaacttcg taagcaggcg
    57181 tttttgagta ttttcgttag aattatgcta tactatttga aaagaatcct gtttaatgtt
    57241 aaggtttctt attttaagaa gaattggagt ttacttatga aagccattat aactgttgtt
    57301 ggtaaagata aatctggaat tgttgcaggt gtttctggta aaattgcaga attaggattg
    57361 aatattgacg atatctctca aactgtattg gatgaatatt ttacgatgat ggctgttgta
    57421 tctagtgatg aaaagcaaga ttttacctat cttcgtaatg aatttgaagc ttttgggcaa
    57481 actttgaatg taaaaatcaa tattcagagt gcagcgattt tcgaagctat gtataatatc
    57541 taggaggtca tcatggatat tagacaagtt actgaaacca tcgccatgat tgaggagcaa
    57601 aacttcgata ttagaaccat taccatgggg atttctcttt tggactgtat cgatccagat
    57661 atcaatcgtg ctgcggagaa aatctatcaa aaaattacga caaaggcggc taatttagta
    57721 gctgttggtg atgaaattgc ggctgagttg ggaattccta tcgttaataa gcgtgtatcg
    57781 gtgacaccta tttctctgat tggggcagcg acagatgcga cggactacgt ggttctggca
    57841 aaagcgcttg ataaggctgc gaaagagatt ggtgtggact ttattggtgg tttttctgcc
    57901 ttagtacaaa aaggttatca aaagggagat gagattctca tcaattccat tcctcgcgct
    57961 ttggctgaga cggataaggt ctgctcgtca gtcaatatcg gctcaaccaa gtctggtatt
    58021 aatatgacgg ctgtggcaga tatgggacga attatcaagg aaacagcaaa tctttcagat
    58081 atgggagtgg ccaagttggt tgtattcgct aatgctgttg aggacaatcc atttatggcg
    58141 ggtgcctttc atggtgttgg ggaagcagat gttatcatca atgtcggagt ttctggtcct
    58201 ggtgttgtga aacgtgcttt ggaaaaagtt cgtggacaga gctttgatgt agtagccgaa
    58261 acagttaaga aaactgcctt taaaatcact cgtatcggtc aattggttgg tcaaatggcc
    58321 agtgagagac tgggtgtgga gtttggtatt gtggacttga gtttggcacc aacccctgcg
    58381 gttggagact ctgtggcacg tgtccttgag gaaatggggc tagaaacagt tggcacgcat
    58441 ggaacgacag ctgccttggc cctcttgaac gaccaagtta aaaagggtgg agtgatggcc
    58501 tgtaaccagg tcggtggtct atctggtgcc tttatccctg tttctgagga tgaaggaatg
    58561 attgctgcag tgcaaaatgg ctctcttaat ttagaaaaac tagaagctat gacggctatc
    58621 tgttctgttg gattggatat gattgccatc ccagaagata cgcctgctga aactattgcg
    58681 gctatgattg cggatgaagc agcaatcggt gttatcaaca tgaaaacaac agctgttcgt
    58741 atcattccca aaggaagaga aggcgatatg attgagtttg gtggtctatt aggaactgca
    58801 cccgttatga aggttaatgg ggcttcgtct gtcgacttca tctctcgcgg tggacaaatc
    58861 ccagcaccaa ttcatagttt taaaaattaa gaaaatagga gaaattttaa gttctattta
    58921 agattagacg tgtatactat aatcattaaa taaagacctc ctaatattat ttgaaacaga
    58981 taacactgaa ttagtttgaa tttgattttc atctaatatc tttatttaat gaactcctaa
    59041 actttttcat aataatctcc ttcaaaagtc gcctgtatgg gtggctttta ttttatcatt
    59101 catgatataa tagaagcaaa cggaggacgg aaaatggtaa aagtacgatt gtatttggta
    59161 cgtcatggca agaccatgtt taacacgatt ggtcgcgcgc aaggttggag cgatactccc
    59221 ttaactgctg aaggtgaacg agggattcaa gagttaggaa tcggtttgcg agaatctgat
    59281 ctacagtttg agcgcgctta ttcgagtgat tctggtcgta ccattcagac catgggaatt
    59341 atacttgaag aacttggctt gcaggggaaa atcccttatc gcatggacaa gcgtatcaga
    59401 gaatggtgtt tcggtagttt tgatggagcc tatgatggcg atcttttcat gggcattatt
    59461 cctcgtatct ttaatgtgga ccacgttcac caattgtctt atgctgaact ggctgagggc
    59521 ttggtagagg tcgatacagc tggttgggct gaaggttggg aaaaactcag tggccgaatc
    59581 aaggaaggct ttgaaataat tgcaaaagaa atggaagatc aaggtggagg taacgcactt
    59641 gttgtcagcc atggaatgac tattggaacc attgtttatc tgattaatgg catgcatccg
    59701 catggtctag ataatggtag cgtgacgatt cttgaatatg aggacggtca gtttagggtt
    59761 gaagttgtcg gtgaccgtag ttaccgagag ctaggacgtg agaagatgga agaaggctct
    59821 atttaatcag tctagacttg cttgccatga gctagggatt tgataaggat atcaagataa
    59881 gaaaaaacag ccgagggtac tcctttcggc tgtttttgat gtggaaaact aaagtgtaat
    59941 gctattgctt ttagagattt tcataaacaa gagcaaggaa cctactgtta gaacagtcag
    60001 gatagttgac aaggctgcgg ctacaccgta atttcctctg agaacctctg tataaatagc
    60061 tacagtcatt gttcttgttt tgacattgta gaggaggata gaagtagaga gttttgaaat
    60121 cattgtgacc caagataaga tggctccaga aatgatacca gatagcatca ttggagttgt
    60181 aatcttagca aaggtattga gacgactact tcctaagctt tcagcagctt cttcaatact
    60241 tggtgctatt tgttgtaagc tagcaacaga tgagcgaata gtataaggta atcttctgac
    60301 agatagagac ataatcaaga tgaaagcagt ccctgtaatc ataagaaatc cacttccaaa
    60361 tagaccagag aaatgaaggc aatccctaga acggttcctg gtacaatata aggtaccata
    60421 ctgaggctgt caattaagtt tgtaaacaaa ttccgttttc taacggctag gtaggagata
    60481 aatgtcgcaa atagaacaac tagaactaag gcaatcaaag ggatacgaat ggtattgaaa
    60541 atagcagatc ccatacgatt gaaagctacc ttgtaactgt ttggagaata acctttaaca
    60601 aataccatac ctgatgtttt taggaaagag gtataaatta agtagatttg aggtaaaaca
    60661 gagataaaga taattccgta gactgttgca taaatggcag ccatttttcc ttttgtagtt
    60721 tttttaggct caattggatg gagcagattc atgctgaaac tgtagcggtt tgcaatgtgt
    60781 ttttggataa ggaaaattgc caaggcaatg ataatcgcca taattgcaaa agcagaattt
    60841 cctccaacct cgctaataaa ttgggtataa atcaggacag ggaaagtccg atatccttcg
    60901 ccaatcaaca taggcgttcc aaagtctgag aatgctctca taaatacaag caaggagctg
    60961 ctagtaaggt tggaactagg agaggtaaaa caaccgttac gataggttta aatccgaagg
    61021 accccatgct ttcagctgct tcaagtagag aattgtcaat actgttcatt gttccagcaa
    61081 catatagaaa taccagtggg aatagttgca gtgtaaagac aagtacaatt cctttgaatc
    61141 cataaatatc gatagctgga agatgaaggg catttgtcaa aaatttagtg atgaccccat
    61201 ttcgtcctag caagagaacc caggagtagg ctcctacgaa aggagctgac atggaagcaa
    61261 tgataatcaa tatttgtaga aatttcttct ccttgaagtc atacatagag aagagataag
    61321 ctaatagggt tcctacaact aaggaagtga cagtagcggt aatggaaacc ttgaaactgt
    61381 tgactagtgt ctcagagtag tagactttac taaagaaagt gacaaaatta gctagtgaga
    61441 attgtccttc atgtataagt gcttgcttga gcacggtaac gataggataa acgagaaaga
    61501 caagataggt aagaaagatg aagaaagagg aggttgtcca aatatttagt tttttacatt
    61561 ccatggttga ctccttttat caggttttgg gaaccatctg cagaaaagat gtttaatttt
    61621 tgcgtattga ttcgtagacg aatacgattg cctttttgta gttcttcttc aaaagttgat
    61681 tcttcactaa cttgaatttt tgaggcaaaa cctgtctcaa tgaaatactc cgtatttagt
    61741 ccaagataga cgctatcgct aatagttcct tcaatatctc cagattcatc tttgataaac
    61801 tcttcgggac gaatgcttac atgaatagct tgctcctcaa cctgatcaag agctggcatt
    61861 cgaagggcat agccatctga aaagacgata taagcgccgt cgctccgttt ttcaagatta
    61921 gtagggataa tatttgtgcg tccgataaag gttgccacaa actcattagc tggtttatga
    61981 tagagttctt ttggtcggcc gatttgttgg atcaccccat ctttcataac agcaatttgg
    62041 tctgaaatag ccatggcttc ttcttggtcg tgggttacat aaacagttgt aattcccact
    62101 tcgtgttgga ttgctcggat ggcttgacgc atatccaagc gaagtttggc ctccagatta
    62161 ctaagtggct cgtccatgag gagaacactt ggattaaccg ctaaggcgca tgccaaggtg
    62221 acacgttgtt gttgtccacc actgagttta tcgggctttc aatccgcata ttgagcaatt
    62281 tgcatgagtt caagatactt gttggtctgt tgaatcaatt cttcttttgg aaccttcttt
    62341 tgcataagac caaaagcaac gttgtctcgg acagtcaaat gtgggaaaat agcgtagttt
    62401 tggaaaacca gcccgatatt gcgtttgctg ggttccatat tattgatttt tgtatcatcg
    62461 aagtaaaatt ctccatcttt gatactgttg aaacctgcaa tcatacgaag aagggtcgtt
    62521 ttcccacatc ctgaagctcc aagaagggta aagagacttc cttttggaat tgtaatgttc
    62581 aaattctcaa taacagggac atcgtggtag atttttttgg cgttaataat ttcgatctca
    62641 ctcatagtga acctctttta ctgtttagat tggatatctg taaagacttc gttgtatttc
    62701 ttaacgatat ctgatttatt cttgatgaca taatcataat cttcagtgag tgttttgatt
    62761 ttgtcaattg gtttcatgtt ttcgcttgtt ttagcatttt tacgaacagg acggttagta
    62821 gtggttgtac caagtgtatc ttgtacttct tgagagataa taaaatcgat aaatttcttg
    62881 gcattttcca tatttttagc ttttttaacg atagcagcac tagcaggtag gaagacggtt
    62941 ccttcttttg gatagactac tttaatgtta gctccgtcat ttaagagttt aactgctgga
    63001 tcctcataag agagaccaac agccatttct ccatcaacga ctgctttata gacaccagat
    63061 gaacttgaac cgattttata gtgtattgaa actagaatag tacacctcta cttctaaaac
    63121 attgttagaa atcgatttga ctgtcctgat taatttgtcc tgttcttatt tcattttact
    63181 ataccatcaa taagtgtgaa aagatctttt acataagacc aagccttatc atctttgtaa
    63241 ccaccttgag cttgtagcat atttgttaat tgagcaaagg cgctagaaga gtttgctggg
    63301 tcagcagttg cgatttttcc ttttagttca ggtttgagaa ggtcgctata tccttcgatg
    63361 ttcatgcctt tagttaaatc agggtggacg attaaaacac taccatctag tgtataagga
    63421 gtagagaagc cagttgtgtt ttgatattct ttgataacat tatcattttc ttttgaaata
    63481 tagttttcaa agagttctcc gtgggtagca tattgtgtat aagaaccacc aaagataaca
    63541 tcagctacag gaacttcttt ttctgactct agttttttga aaagttctcc agtaccagct
    63601 tgaatcagtt ctattttgat accatatttt tcttcaaagg caggaatagt tgctccaatt
    63661 aagccttctg agtttggtga ataaacgact agcgaaccac cgtctccttt atcagatgaa
    63721 ctgtcatcgg cagattcatt agaagaacaa gcagcataat acatccattt ctttttcatg
    63781 atggatacct ccgttgtgtt atttaagttt attttaaaac aatgtaagcg tttttaaaac
    63841 ctacaattct attctatagt gtattgaatc tataacagta cactttgact gctaaaatat
    63901 ttctataaat taatttgact ttcctgatag agatgttcac atcttatttc aattcactat
    63961 attagagtaa aattctctac aaaaagaaga atagcctatt tgactattct tccgagtgat
    64021 ttcaatttct ttggggaaat atggagatac tttttaaata ctttggcaaa atatttatag
    64081 tctgaaaatc caacttggtc agagatagcg cttaaagggg agttgggaga ttcagccatc
    64141 ttatctatag cttgtttcag gcgatattgt aagatatatt catttagagt catggggaag
    64201 tcttctttga taaccttata tagatgcttg ttatctgcaa atagctagag catttcaagg
    64261 aaataaacta gaaataacaa ttaatatggt ggttcagaaa taccttttga taatcaataa
    64321 gatcttcagg atgaagtgcg ttgattccat ccatttcata tttccgattt aataaacgat
    64381 atttgttttc accaaattga tgaaaaggga gtagttgaac ttggtcgata tttaatgagt
    64441 taaatagagt agcgaatttt tctgcatcct ctaaactatt gttaaaatta ggaataactg
    64501 ggattcttaa aacgatagtt ttattttgag aaaaagcata atgaatgttt ttaataatca
    64561 tttgattaaa aaccccagtc acttttttat gttttataga attataatgt tttaggtctg
    64621 tgtagataaa atccacatat tgaattaaat caataaattt ttcatgatca acaaaggcag
    64681 tagtttcaat ggcagtgtgt atgtgatgtt ctttagctga ttttaagatg gctttagcaa
    64741 attcaaactg agcaaatatt tcacctcctg ataaagttaa acctccaccg gattcttcgt
    64801 aaaattcttt gtcttttaat acctctgtaa taatttcttc tacagtcttt tcttcaccga
    64861 ctaaggtgaa tttctctcgt tgagcatctt tcattttttc aggtttcatt ctttgagatt
    64921 caggattaga acaccatgga cagcgcagag gacatccttt taaaaaaaca gttgtacgaa
    64981 tacccgggcc gtcatgaatt gaaaagtgtt gaatattaaa aataattcct ttagatattt
    65041 ccataagagt tcctcctctt cataagtcta tcctatcaca aaaacgaaag aaaaacaatt
    65101 acgaacgaaa gtttaatttg ttgttttttg ctttttattt tggtagaata aaacggaggt
    65161 gtaaaatgaa aagattggaa caaattatta aattagtatc agaatatgaa aagatcgacg
    65221 ttaatacatt atcggaaaaa ttaaatgtat cgaaagtaac gattagaaaa gatttagata
    65281 aattagagtc aaaaggttta ttacacagag agcatggata tgctgtatta aatagtggag
    65341 atgacttaaa tgtacgtttg tcaattaact atgaaattaa gagaaaaatt gttcaggaag
    65401 cagtaaaatt ggtgtcagat aatgaaacaa taatgataga atctggatcg acctgtgctt
    65461 tacttgctga ggaaatttgc aagcaaaaaa gaaatgttac gattgtaaca aattcatttt
    65521 ttatagcaaa ttttgtgaga gcttatgatt catgtcgtat tattgttctt ggtggagagt
    65581 ttcagaagga ttcacaggtt actgtgggac ctttattaaa agaaatgata cagacttttc
    65641 atgtgcatca agcttttgtt gggacagatg gttacgataa agagatgggc tttacaggaa
    65701 aagatttaat gcgcagtgag gtagttcaat atatttcagc agcgtcggat aaagtcattg
    65761 tactaactga ctcaagtaaa tttgataaaa ggggtacagt aagaagattt gctttaagtc
    65821 aagtctatga agtaataaca gacgaaaaac tttctaaaca aaatatagct acattagaaa
    65881 atgctgggat aatggttaag gtagtttcgt aagaggttaa atgtatgaat caagatagga
    65941 ataaactgct ctctaaaatt gcttatctgt attatattga aaacttaaat cagtcacaaa
    66001 tagcagcaaa attaggaatt tatagaacct ctattagtag aatgttaaca gaagcaagga
    66061 atgcaggaat tgttaaaatt gaaatagaga attttgatac caatatgttt aagttggaaa
    66121 attatgtaaa agaaaaatat ggtctggaaa gtttagaaat tattccaaat gaatttgatg
    66181 ataatccaac aattttatct gaaagaattt ctcaagttgc agcaggtgtc cttaggaatc
    66241 taattgatga taatatgaaa attggctttt cttgggggaa aagtttaagt aatttagtag
    66301 atttaattca cagtaaaagt gtccgaaatg ttcacttcta tcctctagca ggtggtccta
    66361 gtcacataca cgctaaatac catgtgaata cactgattta tgaaatgtct agaaaatttc
    66421 atggagagtg tacatttatg aatgcaacga ttgtgcaaga aaataaattg ttagcagatg
    66481 gtattttgca atcaagatat tttgaaaatt tgaaaaatag ttggaaagat ttagatatag
    66541 ctgtagtcgg aattggtgat tttagcaata aaggaaagca tcaatggtta gacatgctta
    66601 cagaggatga ctttaaagaa ttgaccaaag ttaaaactgt aggagaaatt tgttgtcgat
    66661 tttttgattc aaaaggtaaa gaagtctatg aaaacttaca ggaaagaacg atagcaatct
    66721 ctttggaaga tttaaaaaat attcctcaaa gtttagctgt tgcttacggt gatacgaaag
    66781 tatcttcgat tctttctgtc ttgcgtgcta atttagtaaa tcatttgatt acagacaaaa
    66841 atacaatttt aaaagttttg gaagaagatg gggatttgac ttttagagag attctaggtg
    66901 agtgaaaatg atagactgat tcagtttatc gtttttcttt ttagttgatt gcacatttgt
    66961 gcttatataa acaaaaatag tttatctgtt gtttttggat tgacaacttt attatgtagt
    67021 tgtattctat agttacaaaa gaaaatttta aaatttcaaa tgaaaaaagc tttttacata
    67081 gtgaaatgag gaggaattta tggaaattat tgttccagat caaattatca tgggtttaat
    67141 tttatatgct ggtgatgcga aacaacatat ttataaagcg ttagattaca taaaaaatgg
    67201 tacatgtgaa cggtgtgaag aagaaatcca gttagctgat gcagccttat tagaagctca
    67261 taatctacaa acaaaattct tggcacagga agcgtctggt acaaagacag aaattacagc
    67321 tctctttgtt cattcacaag atcatctcat gaccagtatg acggagatta atttaatcaa
    67381 agaaattatt agtttgagaa aagaacttca taaaaaataa tactagagta ttatcattgt
    67441 tattaacata gaggaggaaa acataatggt gaagattggt ttgttttgtg cagcaggttt
    67501 ttctactggt atgcttgtaa ataatatgaa aattgcagcg caatctagtg gagttgaggc
    67561 agaaatagag gcgttttctc agtctaaatt agcggattat gcgccaaata tagatgttgc
    67621 actattgggt ccacaagttg cttatacatt agataaatca aaagaaattt gtgataagtg
    67681 tgatgttccg atagctgtta ttccgatgat ggactatggt atgttagatg ggaaaaaagt
    67741 attagatttg gccctatctt tgattagtgg gtaagaaaag gagatttatt atgtcaaaga
    67801 tggatgttca gaaaatcatt gcaccgatga tgaagtttgt gaatatgcgt ggcattatag
    67861 ctctaaaaga tgggatgtta gcaattttgc cattgacagt agttggtagt ttgttcttga
    67921 ttatgggaca attgccgttc gaaggattaa ataagagcat tgctagtgtt tttggagcta
    67981 attggacaga gccgtttatg caagtatatt caggaacttt tgctattatg ggtctaattt
    68041 cttgtttttc aattgcctat tcttatgcta agaatagcgg agtagaggct ttaccagctg
    68101 gagttctatc tgtatctgca ttctttattt tgctaagatc atcttatatc cctaaacaag
    68161 gtgaggcgat tggggacgct attagtaaag tttggtttgg aggccaagga attatcggtg
    68221 ctatcattat aggtttggta gtaggaagta tttatacctt ctttataaag agaaaaattg
    68281 ttattaagat gccagaacaa gttccacaag ctattgccaa acagtttgaa gcaatgattc
    68341 cagcatttgt aattttctta tcttctatga ttgtatatat tttagcgaag tcattgacta
    68401 atggcggaac attcatagaa atgatttatt ctgctattca agttccgttg caaggtttaa
    68461 ctggatcttt gtatggtgct attggaattg cattctttat atcatttttg tggtggtttg
    68521 gtgttcatgg gcaatcggta gtaaatggag tagtgacagc tctgctttta tctaatcttg
    68581 atgctaataa agctatgtta gcctctggta atctatcatt agaaaatggt gcacatattg
    68641 ttactcaaca atttttagat tcatttttaa ttctatcagg ttcagggatt acgtttggtc
    68701 ttgtagttgc catgcttttt gcagcaaaat caaaacaata ccaagcctta ggaaaagttg
    68761 cagcttttcc agcaatattt aacgtaaatg agccagttgt atttggattt ccgattgtca
    68821 tgaatccagt tatgtttgta cctttcattc ttgttcctgt acttgcagct gtgatagtat
    68881 atggagctat tgcaacaggt ttcatgcagc cattctcagg ggtaacattg ccttggagta
    68941 caccagctat tctatcagga tttttggtgg gtggatggca aggtgttgtg actcagttat
    69001 tagtattggt gatatctaca gtggtttact ttccattctt taagatacaa gatcgtttag
    69061 cttaccaaaa tgaaatcaaa caatcttaga ggtatttgtg tgttactgtt aaactcacac
    69121 atttgtgcta aaaattagag agttaaaatt tttctagtta aaagcttgaa aatttctata
    69181 aaaatcggta ttatattttc gaaagaaata aaaatatttt cgaaagaaag gtgcttacga
    69241 tggtaaatac agaagtagca agaacaacaa tcaagacaga atattttggc agccttactg
    69301 aaaggatgaa caaatatcga gaagatgttt taaataaaaa accttatatt gatgctgaga
    69361 gagcagttct agcaacacgc gcctatgaac gatacaagga acaacctaat gtcctaaaac
    69421 gtgcatatat gctgaaagaa attttggaaa atatgtctat ctatattgaa gaagaatcta
    69481 tgattgcggg aaatcaagct tcttccaata aagatgctcc tatttttccg gaatatacgc
    69541 tagaatttgt tctcaatgag ttggatcttt ttgaaaagcg tgatggagat gttttctata
    69601 ttacagaaga aacaaaagaa caacttagaa gtattgctcc gttttgggaa aataataatt
    69661 tacgtgctag agctggtgcc ttattacctg aagaagtgtc tgtttatatg gaaacaggat
    69721 tcttcggtat ggaaggtaag atgaattctg gagatgctca cttagcagtt aactatcaga
    69781 aacttttgca atttggttta agaggttttg aagagcgggc tcgtaaagca aaagtagctc
    69841 tagatttaac agatccagca agtattgata aatatcattt ttacgactct atatttatcg
    69901 taatcgatgc tattaaagta tatgcaaagc gctttgttgc tcttgctaaa agtttagccg
    69961 aaaatgcaaa tcctaaacgt aagaaagaat tacttgagat tgcagatatt tgctctagag
    70021 tcccatatga accggcaact acttttgcag aagctattca atcagtttgg tttattcaat
    70081 gtattttaca aattgaatct aatggccact ctctttcata tggccgtttt gatcaatata
    70141 tgtatccata tatgaaggct gatttagaaa gtggtaaaga aacagaagat agcattgttg
    70201 aacgtctgac aaatctttgg attaagacaa ttacaattaa taaggttcgc agtcaatcac
    70261 atacattttc ttcagcagga agtcctttat atcaaaatgt tacaattggt ggacagactc
    70321 gagataagaa ggatgctgtt aacccattat cttatttggt cttaaaatca gttgcacaaa
    70381 cccatctacc gcaacctaat ctaactgtac gttaccatgc aggtttagat gctcgtttca
    70441 tgaatgagtg tattgaagtg atgaaacttg gttttggtat gcctgcattt aataatgatg
    70501 agattattat tccttctttt attgcaaaag gagtattgga agatgatgct tatgattaca
    70561 gtgccattgg atgtgttgaa acggcagttc cagggaaatg gggctatcgt tgcacaggta
    70621 tgagttatat gaacttccct aaggttctac ttatcacgat gaatgatgga attgatccgg
    70681 cttcgggtaa acggtttgca ccaagctttg gtcattttaa ggatatgaag aacttttctg
    70741 aattagaaaa tgcttgggat aaaacactaa gatatttgac acgaatgagt gttattgttg
    70801 aaaattctat tgatttatca ttggaacgag aagttcctga tattctatgt tcagcattga
    70861 ctgatgattg tattggtcgt ggaaaacacc ttaaagaagg tggagcagta tatgattata
    70921 tatcaggatt gcaagttgga attgcaaatt tgtcggattc attagctgca attaaaaaat
    70981 tggtgtttga ggaagaacgt ataagcccaa gtcagctttg gcatgcactg gaaacagatt
    71041 atgccggaga agaaggtaag gtcattcaag aaatgttgat tcatgatgca cctaagtatg
    71101 gtaatgatga tgattatgct gacaaattgg ttactgctgc ttatgacatt tatgttgatg
    71161 aaattgctaa atatcctaat acacgttatg gaagaggtcc aattggagga attcgttatt
    71221 caggaacatc ttctatctca gccaacgtag ggcagggacg tggaacatta gcaactccag
    71281 atggacgcaa cgcgggtaca ccgttagcag agggttgttc accatcacat aatatggatc
    71341 aacacggccc tacatctgtt ttaaaatctg tttcaaaatt accaacagat gaaatcgtag
    71401 gtggggttct cttaaatcag aaagtaaatc ctcaaacgtt agccaaagaa gaagataaat
    71461 taaaactaat tgctttgtta cgaacattct ttaatcgttt acatgggtac catattcaat
    71521 acaatgttgt ttccagagag acgctgattg acgctcagaa acatcctgaa aaacacagag
    71581 acttaattgt tcgtgttgca ggatactctg cattcttcaa tgttctttct aaggcaaccc
    71641 aagatgacat tataggacgt actgagcata ctttgtaaaa taaagaggtt ctttttatgg
    71701 aatttatgct tgacacatta aatttagatg agattaaaaa gtggtctgaa attttgccgc
    71761 tagctggggt aacttcaaat cccactattg caaaaagaga gggttctatt aatttttttg
    71821 aacgaatcaa agatgtaaga gaattgattg gctctacacc ctctattcat gttcaggtga
    71881 tttctcaaga ttttgaaggc atcttaaagg atgctcatga aattcgaaga caagcaggag
    71941 atgatatatt tatcaaagta cctgttactc cagctggatt acgtgcaata aaggtgctaa
    72001 aaaaagaggg ctaccatatc actgcaacag ctatttatac agttattcag ggattattag
    72061 ctatcgaagc aggagcggat tacctagctc catattataa tagaatggaa aatctgaaca
    72121 ttgattcaaa ttctgtcatt cgtcaattag ctcttgctat tgatagacag aactctccta
    72181 gtaagatttt agctgcatcc tttaaaaatg tagcacaagt aaataatgct ttagctgcag
    72241 gtgcgcatgc tgttacagca ggagcggatg tttttgaatc agctttcgcc atgccatcta
    72301 tccaaaaggc ggttgatgat ttttctgacg attggtttgt tattcaaaat agtcgttcca
    72361 tttagataga gaggaaatac atatgagaat ttttgctagt ccttctagat atattcaggg
    72421 ggaaaatgcc ttgtttgaaa atgccaaatc aattttggat ttgggaaatt gccctattct
    72481 attatgcgat cagttggttt atgatattgt tggaaaacga tttgaagatt acctacatag
    72541 gtatggtttc catattgttc tggcgctatt taatggtgaa gcttctgaca atgaaatcaa
    72601 tcgagttgtt gccttggctg agaaagaaaa ttgtgatagt attatcggtc ttggtggggg
    72661 aaagacgatt gatagcgcaa aagctattgc agatttgatt gaaaagtctg ttattattgc
    72721 tccaacaatt gcatcgaccg acgcacctgt atctgcttta tctgttattt atacagatga
    72781 aggtgcattt gatcattatc tattttattc taaaaatcca gatttagttt tggttgatac
    72841 aaaagttatt tcacaagccc ctaagcgttt attagcgtct ggtattgcag atggtttagc
    72901 aacttgggtt gaggcgcgtg cggttatgca ggcaaatgga aaaactatgt tgggacaaca
    72961 gcaaacattg gctggagttg caattgcgaa gaaatgtgaa gaaacgctgt ttgcagatgg
    73021 tttacaggct atggcagctt gtgaagctaa agtggtgaca ccagcattag aaaatattgt
    73081 tgaagctaat actttattga gtggtctagg ttttgaaagt ggaggattag ctgcggcgca
    73141 tgcaattcat aatggtttta ctgcattgac aggtgacatt catcatttaa cacatggtga
    73201 aaaagtagct tatggaactt tagtacaact attattggaa aatagaccta aagaagaact
    73261 tgataagtat attgagtttt acaaaaaaat tggtatgcca acaactctaa aagaaatgca
    73321 tttggatcaa gttggatatg atgatttaat aaaagttggt aaacaagcaa ctatggaggg
    73381 tgagacaatt catcagatgc cgtttaagat ttcgccttca gatgttgctc aagctattat
    73441 cgctgtagat gcctatgtaa attcaaaata aacaataagg actactgttt tccaaatggt
    73501 agtcttttat tgatcctcgt attgaattct atagcagatt gaaataagat gagaacaaat
    73561 cgattgggaa agtaaaatta atttctataa atgttttagc aattgtttcg tactatttca
    73621 gattcagtcc actatacgtt cttcataaat caaaaagcga cataggttgt cggctattta
    73681 ttgtgaatac attaattagc attccagttt tatcttcggt ctaaaataag tattttgtgc
    73741 tatacgagat aagcttcttg acttactcct tgatttactg cataacaatg ggataaaaag
    73801 tgggagatag agcaattcat agtcatcaaa attaatgaga tacagtatac agtttttcct
    73861 ttaaacacat ttcaaattcc ctcaaaaatg gtataatagt aacatcacaa aattggagag
    73921 agaccatgag tttttacaat cataaagaaa ttgagcctaa gtggcagggc tactgggcag
    73981 aacatcatac atttaagaca ggaacagatg catcaaaatc taagttttat gcgcttgata
    74041 tgttccctta tccgtctgga gctggtctgc acgtaggaca cccagaaggt tatactgcaa
    74101 ccgatatcct cagtcgttac aaacgtgcgc aaggctacaa tgtccttcac ccaatgggtt
    74161 gggatgcttt tggtttgcct gcagagcaat acgctatgga tactggtaat gacccagcag
    74221 aatttacagc ggaaaacatt gccaacttca aacgtcaaat caatgcgctt ggattttctt
    74281 atgactggga tcgtgaagtc aatacaacag atccaaacta ctacaagtgg actcaatgga
    74341 ttttcaccaa gctttacgaa aaaggcttgg cctatgaagc tgaagtgcca gtaaactggg
    74401 ttgaggaatt gggaactgcc attgccaatg aagaagtgct tcctgacgga acttctgagc
    74461 gtggaggcta tccagttgtc cgcaaaccaa tgcgccaatg gatgctcaaa atcacggctt
    74521 acgcagagcg cttgctcaat gacttagatg aactagattg gtcagagtct atcaaggata
    74581 tgcaacgcaa ctggattggt aaatcaactg gtgccaatgt aactttcaaa gtaaaaggaa
    74641 cagacaagga atttacagtc tttactactc gtccggacac acttttcggt gcgactttca
    74701 ctgtcttggc tcctgaacat gaattagtag acgctatcac aagttcagag caagcagaag
    74761 ctgtagcaga ctataaacac caagccagcc ttaagtctga cttggctcgt acagaccttg
    74821 ctaaagaaaa aacaggggtt tggactggtg cttatgccat caaccctgtc aatggtaagg
    74881 aaatgccaat ctggattgca gactatgtcc ttgctagtta tggaacaggt gcggttatgg
    74941 ctgtgcctgc ccacgaccaa cgtgactggg aatttgccaa acaatttgac cttccaatcg
    75001 tcgaagtact tgaaggtgga aatgtcgaag aagctgccta cacagaggat ggcctgcatg
    75061 tcaattcaga cttcctagat ggactcaaca aagaagacgc tattgccaag attgtggctt
    75121 gcttggaaga aaaaggctgt ggtcaggaga aggttaccta ccgtctccgc gactggctct
    75181 ttagccgtca acgttactgg ggtgagccaa ttccaatcat tcattgggaa gatggaactt
    75241 caacagctgt tcctgaaact gaattgccgc ttgtcttgcc tgtaaccaag gatatccgtc
    75301 cttcaggtac tggtgaaagt ccactagcta acttgacaga ttggcttgaa gtgactcgtg
    75361 aagatggtgt caaaggtcgt cgtgaaacca acactatgcc acaatgggct ggttcaagct
    75421 ggtactacct ccgctatatt gatccacaca atactgagaa gttggctgat gaggacctcc
    75481 tcaaacaatg gttgccagta gatatctacg tgggtggtgc agagcatgct gttcttcact
    75541 tgctttacgc tcgtttctgg cacaaattcc tctatgacct cggtgttgtt ccgactaagg
    75601 aaccattcca aaaactcttt aaccaaggga tgattttggg aacaagctac cgtgaccacc
    75661 gtggtgctct tgtggcaacc gacaaggttg aaaaacgtga tggttccttc ttccatgtag
    75721 aaacagggga agagttggag caagcgccag ccaagatgtc taaatcgctc aagaacgttg
    75781 ttaacccaga cgatgtggtg gaacaatacg gtgccgatac ccttcgtgtt tatgaaatgt
    75841 ttatgggacc actcgatgct tcgattgctt ggtcagaaga aggtttggaa ggaagccgta
    75901 agttccttga ccgagtttac cgtttgatta caagtaaaga aatccttgcg gaaaacaatg
    75961 gtgctcttga caaggtttac aacgaaacag tcaaagctgt tactgagcaa attgagtctc
    76021 tcaaattcaa cacagctatt gcccaactta tggtctttgt caatgctgct aacaaggaag
    76081 ataagcttta tgttgactat gccaaaggct ttattcaatt gattgcacca tttgcacctc
    76141 acttggcaga agaactctgg caaacagtcg cagaaacagg tgagtcaatc tcttatgtag
    76201 cttggccaac ttgggacgaa agcaaattgg ttgaagatga aattgaaatt gtcgtccaaa
    76261 tcaaaggaaa agttcgtgcc aaactcatgg ttgctaaaga tctatcacgt gaagaattac
    76321 aagaaatcgc tttagctgat gaaaaagtca aagcagaaat tgacggtaag gaaatcgtga
    76381 aagtaattgc ggtaccgaat aaactcgtta atatcgtcgt taaataacga gtttattagc
    76441 tctatctgcc accttcaata gtccactgga ctattgaagc caactaaatt agttaacatt
    76501 gttgtgaaat aaaaagaagt aactctagag tatgaacttt agagttactt ttagaatagg
    76561 tcagaatgaa tagattagtg aacgatagca ggaagtgtga aattttatta tttaagattt
    76621 ctattattgt agtgtcagtt atagtattag taatgtcaat agtgggtgca tattatttta
    76681 aaaattgtct ttgggacaag gaaagtttaa atttgacact cactttagac actctctttg
    76741 cagtttttat tactttcttt agtttttcaa atgataaatc aagcaatatt tttggaatat
    76801 ctccaaatga aattataagg acacagtctg aagtgtatca atttttattt acaaaatctt
    76861 ttgcaactct attaatagtg acaaatttgt tatccattat tcattatttt ggagccaaaa
    76921 atttaatagt ttcttttaat gaaacttatc ctcgtattca atccagtgtt ggtatcatgt
    76981 ggctaccact gtttggtatt ctgataatct attttatttg gctcttaata gagggattaa
    77041 aatatatcag aaaaataaat tatattattc aaaataggga aataatctat ttttattcgc
    77101 aggtaaaagt tgtagataaa cttactgatt ctgaatcgaa aaaatacggt gaatatattg
    77161 atttgtacga atcgtgtcgt cagaacaatt taagtgttct acttaacttt cttcaaaatt
    77221 cggatgataa acgaggagtt attgctagta actcagtgag aattatgttt gaatctttgg
    77281 ataaagcaga ccaaattgcg gccctgaata tttgtagaaa ctatgtagca cgagaaaatg
    77341 ttttaaataa agaagatgca gaaaaattgt taaatgaaat tgataaaaaa cttgaaatta
    77401 gcagatagga caattcaaat agagttgagt aaaaagtttg aaaagtgaaa caaggagaaa
    77461 gctatgccag taaatgaata tggtcagatg attggtgagt caatggaagg ttatacaccc
    77521 ggtgcactgc cttctattga tttcttagaa gggcgttatg ctaggataga ggctctctcg
    77581 gtagaaaaac atgcggagga tttgctagct gtttatggcc cggatactcc tcgggagatg
    77641 tggacctatc tttttcagga gccagtagca gatatggggg agctggttag ccttttaaat
    77701 cagatgttgg ctcgtaagga ccgtttttac tatgcaatca tagacaaggc gactggtaag
    77761 gctttgggaa ctttttctct catgcgcatt gaccagaata accgagtaat agaagtcgga
    77821 gcagtcactt tttctccaga gctaaggggt acacggatag gaactgaggc tcagtatctc
    77881 ctagctcgct atatttttga ggagctaaac tatcgtcgct acgagtggaa atgcgatgcc
    77941 ttaaatctgc catccagacg agttgcggag cgtttgggat ttgtctatga aggaaccttc
    78001 cgccaggcgg tggtttataa ggggcgtacg agagatacgg attggttgtc tatgattgat
    78061 atggactggc ctcaagtcaa agatcgtttg gaaacatggc tgcgtcctga aaattttgat
    78121 aaaaatggac agcagtacaa gagcttgaga gaactttaag aggtgttgag atgattacta
    78181 ttaaaaagca agaaattgtc aagctagagg atgttttgca tctctatcag gctgtcggtt
    78241 ggacaaatta tacccatcaa ccagagatgc tggagcatgc cttatcgcat tcattagtaa
    78301 tttatctggc acttgatggt gatgctgtgg tgggcttgat tcgtttggtt ggagatggat
    78361 tctcatcagt ttttgtacag gatttgattg ttttaccaat ctatcagcgt caagggattg
    78421 gtagtgccct aatgaaagag gccttaaaag attacaaaga tgcttatcaa gtccagctgg
    78481 tgacagaaga gacagaaaaa aacgtgggat tttatcgttc tatgggcttt gaaatcttat
    78541 ccacctataa ttgtataggg atgacttggg cgaatcgaga aaaataacaa aacttgtttt
    78601 ttcttaagca aaatttaagg atggtctagt attatataat cattaaataa agacctccta
    78661 actttattta ataaaatcct aaactttttt catcacaatc tcctaatgaa gccacccaat
    78721 caggtggctt ttttgcgtgg tgaggtgctg gtgatagaaa ttttttgcaa aatagtaaaa
    78781 ttttagaaaa gttaaggtag ttttaagttt cgtcttgtat catgtagtta ttaaataaag
    78841 acctcctaac tttatttaat aaaatcctaa acttttcttt ttcataataa tctcccttaa
    78901 ctccacccaa tcaggtggag ttttttagct ctatttcagg cttttgggga ctattctaaa
    78961 aataattttt cgatattttt cggtattttt cggattttgg tcggggaatt ggcggggact
    79021 tttttagcga atataactaa gaaataggtc tgtggtcgct tcagctagtt caaactcaat
    79081 ttgattgtaa gtgactgtta attgaagaac tggaactact gtaataatga ttttgcttgt
    79141 ctagtagtgg cgtattaaat gagaagtgac atgtaagatt gtctcttcgt ttacgaaatc
    79201 aaaatttcta tgaaattgat agaatcccta acgttctctt aatcttaacc gtcttgtcgt
    79261 acagcggttg aagaaaatgt aaacctttga caaaattcgt gaactatggg ataataaaga
    79321 ggaattgagt actagttcta tatcataggc tagaaaagac cccaagctca cgaccaaata
    79381 agcttgaggt cttttttgac actatttgtc cttgtttagc tatttatcga ctatacgaag
    79441 aacgacaccg accacaattg gtccgatgat agttttgagt actaattcca tcatgggcta
    79501 tctcacctcc tttcgtaggc ggtgtagcag tgtcgtagaa tattatacca cataagtgct
    79561 aaacttagga gtcacccaat caggtggctt ttttgtttgt ggcttggttt tttgatataa
    79621 tagagccatg agtagaattt tagataatga gataatgggg gatgaggagt tagtagaacg
    79681 cacgctccgt cctcagtatt tacgtgaata tatcggacag gataaggtca aggaccagct
    79741 acaaatcttt attgaagctg ccaaaatgcg ggatgaagcg ctggatcatg tgctcttatt
    79801 tgggcctcca ggtctcggga aaacgaccat ggcctttgtt attgccaacg aactgggagt
    79861 caatcttaag cagacgtcgg gtccagtcat tgaaaaagcc ggagatctgg tagctatttt
    79921 gaatgagtta gagcctgggg atgtactttt tattgatgag atccatcgtt tgccaatgtc
    79981 agtggaagag gtgctttata gtgctatgga ggacttctac atcgatatta tgattggggc
    80041 tggtgagggt agtcgtagtg ttcatttgga gttaccacct tttaccttga ttggtgcgac
    80101 gactcgggct ggtatgctct ccaatccgct acgggcacgt tttgggatta caggccatat
    80161 ggagtattat gcccatgctg acttgacaga aattgtcgag cggacggcag atatttttga
    80221 gatggaaatc actcatgagg cagcatctga gttggcccta cgtagtcgtg ggacccctcg
    80281 tattgccaat cgtctcctca agcgcgtgcg cgattttgcc cagataatgg ggaatggggt
    80341 aattgatgat attattaccg ataaggcttt gactatgctg gatgttgacc atgaaggttt
    80401 ggactatgtg gatcaaaaaa tccttcgtac catgattgag atgtacagtg gaggacctgt
    80461 tggtctagga actctttctg tgaatatcgc cgaagagcgt gagacagttg aagatatgta
    80521 tgagccttac ttgattcaaa aaggttttat catgcggaca cggtctggac gggtggcgac
    80581 tgctaaggca tatgagcact taggttatga atacagtgaa aaataagcaa gaaatcttag
    80641 aggcttttag agaaagtcca gatatgatgg ccattctgac gatcatccga gaccttggtt
    80701 tgaaagactc gtggttggca gcaggttctg tcagaaattt catctggaat cttttgtcag
    80761 acaaatcccc ttttgatcat gaaacagata tagatgtgat tttctttgat ccagattttt
    80821 cttatgagga aaccttatta ctggagaaaa agctgagaga ggattttcct cagtaccagt
    80881 gggaattgaa aaatcaggtc tatatgcatc agcacagtcc tcacactgct tcctatacca
    80941 gttctcgtga tgctatgagt aagtatccag aacggtgtac ggcagttgga ctgcgcttga
    81001 atgaagaatc agattttgaa ctctatgtac cttatggttt ggaggatatt ttgaattttc
    81061 aagttcgtcc aactcctcat ttcttagaaa atgaagaccg aatggaactc tatcaaacac
    81121 gtttatccaa gaaaaattgg caggagaaat ggaaaaattt gatttttaaa aatacttaag
    81181 gaaactttaa gctagggagt gtacactaag ttcataagtt aagaagacct taacttaaac
    81241 tcctaaaact ttttcataat aatctcccta taaaaataaa gtcgcccaat caggcggctt
    81301 atttttttga aaaatgggct tggtgcctga gaataaatag cttagtgata gaagaaaatg
    81361 gggaaatatg gtataatgaa acgatagatt tttgaatagg aataagatca tgtttggatt
    81421 ttttaagaaa gataaggctg tggaagtaga ggttccgaca caggttcctg ctcatatcgg
    81481 catcatcatg gatggcaatg gccgttgggc taaaaaacgt atgcaaccgc gagtttttgg
    81541 acataaggcg ggcatggaag cattgcaaac cgtgaccaag gcagccaaca aactgggcgt
    81601 caaggttatt acggtctatg ctttttctac ggaaaactgg acccgtccag atcaggaagt
    81661 caagtttatc atgaacttgc cagtagagtt ttatgataat tatgtcccgg aactacatgc
    81721 gaataatgtt aagattcaaa tgattgggga gacagaccgc ctgcctaagc aaacctttga
    81781 agctttaacc aaggctgagg aattgactaa gaacaacaca ggattgattc ttaattttgc
    81841 tcttaactat ggtggacgtg ctgagattac acaggcgctt aagttgattt cccaggatgt
    81901 tttagatgcc aaaatcaacc caggtgacat cacagaggaa ttgattggta actatctctt
    81961 tactcagcat ttgcctaagg acttacgaga cccagacttg attatccgta ctagtggaga
    82021 attacgtttg agcaatttcc ttccatggca gggagcctat agtgagcttt attttacgga
    82081 caccttatgg cctgattttg acgaagcggc cttgcaggaa gctattcttg cctataatcg
    82141 tcgtcatcgc cgatttggag gagtttagga ggaaatatga cccaggattt acagaaaaga
    82201 accttgtttg cagggattgc cctggctatt ttcctaccaa ttttaatgat tgggggcctc
    82261 ttgcttcaga tagcaatcgg aatcatagcc atgctagcca tgcatgaact tttgaagatg
    82321 agaggtctag agaccatgac gatggagggc ctcttgaccc tctttgcaac ctttgcattg
    82381 accattccct tggagaatta cctgactttt ttgccagttg atgggaatgt ggttgcctat
    82441 agtgttttga tttcaatcat gttaggaacg accgttttta gcaagtctta tacgattgag
    82501 gatgcggttt tccctcttgc tatgagcttc tacgtgggct ttggatttaa tgctttacta
    82561 gatgctcgtg ttgcaggttt ggacaaggct ctcttagcct tgtgtatcgt ctgggcgaca
    82621 gacagtggtg cctatcttgt tgggatgaac tatgggaaac gaaagttagc accaagggta
    82681 tcgcctaata aaacccttga gggtgccttg ggtggtattt taggagcaat tttagtaacc
    82741 attatcttta tgatagttga cagtacagtt gctcttccat atggaattta caagatgtca
    82801 gtctttgcta ttttctttag cattgctgga caatttggtg atttactaga aagttcgatc
    82861 aaacgtcatt ttggtgttaa ggattctggg aaatttatcc ctggacatgg tggtgttttg
    82921 gatcgtttcg atagtatgtt gcttgtattt ccaatcatgc acttatttgg actcttttaa
    82981 tcaaaagacg gaggaaacac tatgcttgga attttaacct ttattctggt ttttgggatt
    83041 attgtagtgg tgcacgagtt cgggcacttc tactttgcca agaaatcagg gattttagta
    83101 cgtgaatttg ccatcggtat gggacctaaa atctttgctc acattggcaa ggatggaacg
    83161 gcctatacca ttcgaatctt gcctctgggt ggctatgtcc gcatggccgg ttggggtgat
    83221 gatacaactg aaatcaagac aggaacgcct gttagtttga cacttgctga tgatggtaag
    83281 gttaaacgca tcaatctctc aggtaaaaaa ttggatcaaa cagccctccc tatgcaggtg
    83341 acccagtttg attttgaaga caagctcttt atcaaaggat tggttctgga agaagaaaaa
    83401 acatttgcag tggatcacga tgcaacggtt gtggaagcag atggtactga ggttcggatt
    83461 gcacctttag atgttcaata tcaaaatgcg actatctggg gcaaactgat taccaatttt
    83521 gcaggcccta tgaacaattt tatcttaggt gtcgttgttt tttgggtttt aatctttatg
    83581 cagggtggtg tcagagatgt tgataccaat cagttccata tcatgcccca aggtgccttg
    83641 gccaaggtag gagtaccaga aacgtcacaa attactaaga ttggctcaca tgaggttagc
    83701 aactgggaaa gcttgatcca agctgtggaa acagaaacca aagataagac ggcaccgact
    83761 ttggatgtga ctatttctga aaaggggagt gacaaacaag tcactgttac acccgaagat
    83821 agtcaaggtc gttaccttct aggtgttcaa ccgggggtta agtcagattt tctatccatg
    83881 tttgtaggtg gttttacaac tgctgctgac tcagctctcc gaattctctc agctctgaaa
    83941 aatctgattt tccaaccaga tttgaacaag ttgggtggac ctgttgctat ctttaaggca
    84001 agtagtgatg ctgctaaaaa tggaattgaa aatatcttgt acttcttggc aatgatttcc
    84061 atcaatattg ggatttttaa tcttattccg attccagcct tggatggtgg taagattgtg
    84121 ctcaatatcc tagaagccat ccgccgcaaa ccattgaaac aagaaattga aacctatgtc
    84181 accttggccg gagtggtcat catggttgtc ttgatgattg ctgtgacttg gaatgacatt
    84241 atgcgactct tttttagata atcgaggaat attatgaaac aaagtaaaat gcctatccca
    84301 acgcttcgcg aaatgccaag cgatgctcaa gttatcagcc atgctcttat gttgcgtgct
    84361 ggttatgttc gccaagtttc agcaggtgtt tattcttatc taccacttgc caaccgtgtg
    84421 attgaaaaag ctaaaaacat catgcgccaa gaattcgaaa agattggtgc tgttgagatg
    84481 ttggctccag cccttcttag tgcagaattg tggcgtgaat caggtcgtta cgaaacctat
    84541 ggtgaagacc tttacaaact aaaaaaccgt gaaaaatcag actttatctt aggtccaact
    84601 cacgaagaaa cctttacagc tattgtccgt gattctgtta aatcttacaa gcaattgcca
    84661 ctcaaccttt atcaaattca gcccaagtat cgtgatgaaa aacgcccacg taatggactt
    84721 cttcgtacac gtgagtttat catgaaggat gcttatagtt tccacgctaa ctatgatagt
    84781 ttggatagtg tttatgatga gtacaaagca gcctatgagc gtattttcac tcgtagtggt
    84841 ttagacttca aggctattat tggtgacggt ggagccatgg gtggtaagga tagccaagaa
    84901 tttatggcca ttacatctgc tcgtacagac cttgaccgct gggttgtctt ggacaagtca
    84961 gttgcctcat ttgacgaaat tcctgcagaa gtgcaagaag aaatcaaggc agaattgctc
    85021 aaatggatag tctctggtga agataccatt gcttactcaa gtgagtctag ctatgcagct
    85081 aacttagaaa tggcaacaaa cgagtacaaa ccaagcaacc gtgttgtcgc tgaagaagaa
    85141 gttactcgtg ttgcaacgcc agatgttaaa tcaattgatg aagttgcagc cttcctcaat
    85201 gttccagaag aacaaacgat taaaaccctc ttctacattg cagatggcga gcttgttgca
    85261 gcccttctag ttggaaatga ccaactcaac gaagtcaagt tgaaaaatca cttgggagca
    85321 gatttctttg acgttgctag cgaagaagaa gtggcgaatg ttgttcaagc aggatttggt
    85381 tcacttggac cagttggttt gccagagaat attaaaatta ttgcagatcg taaggtacaa
    85441 gatgttcgca atgcagttgt cggtgctaac gaagatggct accacttgac tggtgtgaac
    85501 ccaggccgtg attttactgc agaatatgtg gatatccgtg aagttcgtga gggtgaaatt
    85561 tccccagatg gacaaggtgt ccttaacttt gcgcgtggta ttgagatcgg tcatattttc
    85621 aaactcggaa ctcgctattc agcaagcatg ggagcagatg tcttggatga aaatggtcgt
    85681 gctgtgccaa tcatcatggg atgttacggt atcggtgtca gccgtcttct ttcagcagtg
    85741 atggagcaac acgctcgcct ctttgttaac aaaacgccaa aaggtgaata ccgttacgct
    85801 tggggaatca atttccctaa agaattggca ccatttgatg tgcatttgat tactgtcaat
    85861 gtcaaggatg aagaagcgca agccttgaca gaaaaacttg aagcaagctt gatgggagct
    85921 ggttatgaag tcttgacaga tgaccgtaac gaacgtgtcg gtgttaaatt tagcgatagt
    85981 gacttgattg gtcttccaat ccgtatcact gttggtaaaa aagcggccga tggcattgta
    86041 gaagttaaga tcaaggcaac tggtgacacc attgaggttc atgcagataa cgtgcttgaa
    86101 acgcttgaaa tcctaagcaa gaaataaaaa ctataatcag aagaaaaaca aggaaaaaat
    86161 gtaactagtt tttaccttgt tttttctgta taatgggaga aatgagtaga taaagaggta
    86221 aatgtatgct aagatttcca aaggattttg tctggggatc ctctacttct ggaccgcaga
    86281 cagaaggacg tgtagctggt gacggtaagg gagacaatct ctgggattac tggttccaag
    86341 tggagccaaa tcgttactat aatgggattg gttcagataa gacatcgact ttttatgaaa
    86401 attgggagcg ggatattgag cttttgttag agactggtca cacagccttt cggacttcta
    86461 ttcagtggtc acggattttt ccacaaggct gtggaaaagt caacactcaa ggtgtggatt
    86521 tttatcgtaa ggtctttgag gctattaagg ctaaaggaat tcgtctgtta gtcaatctct
    86581 atcattttga tttacctttt gcccttcaag aggatggtga tggttgggaa aataaggcga
    86641 cagtctcagc ctatgaagac tatgctcgtt tttgttttga gacttatgga gatttagtgg
    86701 atcaatggat tacctttaac gagcccatcg ttcctgtaga atttggttat ttttatgatg
    86761 cccattatcc acataaggtg gatgcagagg cagctgttaa ggtagcctat catacacaat
    86821 tggccagcag ccgggctgtt aaggcttgcc atgaactttt gcctgattcc aagattggga
    86881 ttgtcctcaa cttgacaccg gcttatccac gtagccagca tcctgctgat gtcaaggcag
    86941 ctcgtattgc ggcccttttt caggcccaat ctttcttaga tccatctgtc ttggggactt
    87001 atccacagga gttggtagaa atcttgcatg aacacggtct tttacctgat gctacagagg
    87061 aagagttgga actcattcgt gataatacgg tggacttcct tggtgtgaac tactatcaac
    87121 ctttgcgtgt tatggctcct cgatttgcta agcatccaga gagtccactc ttaccagaac
    87181 atttttacga gccttatgtg atgcctggac gtaaaatcaa ttctcaccgt ggttgggaga
    87241 tttatgagca agggatttat gacatcgccc aaaatatcaa ggaaaattat ggcaatattg
    87301 aatggatgtt gactgagaat ggtatgggtg ttgaagggga agaaaaattc cgtcaagatg
    87361 gaatgattca agatgattac cgtattgact ttgtaaaagg tcatcttcgt gaacttcacc
    87421 gtgccattga agatggtgcc aactgtaagg gctacttgat ttggaccttt attgactgct
    87481 ggtcatggct caacagctat aaaaatcgct atggtttggt cgaattagac ttggaaacgc
    87541 aagaacgtcg tctgaagaaa tcaggccact ggttcaaaaa attaagcgat aataatggat
    87601 tttaaaaagg actctgactg attatcccaa tcggtcagag ttttttgctt acaggagctt
    87661 aatttgaact ataccaattt ttactcttga caagtgaaag aaacaagtat atactgtttt
    87721 tgctgattct ataaaagatg aattagacta taccaatttt aaggagaaag cacagcttgc
    87781 ctgtgtcgta tatactatgt gtggaattgt tggtgttgtt ggaaacacaa atgcaactga
    87841 tattttgatt caagggcttg aaaagcttga ataccgtggc tatgattctg cgggaatttt
    87901 tgtcctagat ggtgctgata accatttggt gaaggctgtt ggtcgtattg cagaattgtc
    87961 tgccaagaca gatggtgttg agggaacaac tggtatcgga catactcgtt gggctactca
    88021 cggaaaacca actgaggaca atgctcaccc acaccgctct gagacagaac gttttgtctt
    88081 ggtgcataat ggggtgattg agaactacct tgaaatcaag gaagaatacc ttgcaggtca
    88141 ccacttcaag gggcagacag atactgaaat agccgttcat ttgattggaa aatttgcgga
    88201 agaagaaggg ctctcagttc ttgaagcctt caaaaaagcc cttcacatca tccgtggttc
    88261 ttatgccttt gccttggttg actcacaaga tcctgaagtc atctacgtag ctaaaaataa
    88321 atcaccactt ttgattggtc ttggagaagg ctataacatg gtctgctcag acgccatggc
    88381 tatgattcgt gaaactaacc aatacatgga aatccatgac caagagttgg taatcgtcaa
    88441 ggctgatagt gtggaagttc aagactatga tggaaatcgt cgtgagcgtg ctagctacac
    88501 tgctgaactt gacttgtcag atatcggtaa gggaacttac ccttactaca tgctcaagga
    88561 aattgacgag caaccaactg ttatgcggaa actcatccaa gcctacacag atgaggctgg
    88621 tcaagttgtc gtagacccag atatcattaa ggctgttcaa gacgcagacc gcatctacat
    88681 ccttgcagct ggaacatctt accatgcagg atttgcttct aagaaaatgt tggaagaatt
    88741 gacagataca ccagttgaac ttggaatctc atctgagtgg ggctacggta tgccacttct
    88801 cagcaagaaa ccactcttca tctttatcag ccaatctggt gaaacagcgg atagtcgtca
    88861 agttttggtc aaggctaatg aaatgggaat tccaagctta acagtgacaa atgttccagg
    88921 ttcaaccctc tcacgtgaag ccaactatac catgctcctt catgcaggtc ctgaaattgc
    88981 tgtggcatca actaaagcct atacagcgca aatcgcagcc cttgccttcc ttgcaaaagc
    89041 agtcggagaa gcaaatggta atgctaaagc gcaagtcttt gatctggttc atgaattgtc
    89101 aatcgtagct cagtctatcg aatcaactct ttcagagaaa gaaaccattg aagtcaaggt
    89161 tcgtgaactt cttgaaacaa ctcgtaacgc cttttacatc ggacgtggtc aagattacta
    89221 cgtagccatg gaagcaagtc tcaaactcaa agagatttct tatatccagt gtgaaggctt
    89281 tgctgcagga gaactcaagc acggaaccat tgccttgatt gaagaaggaa cgcctgtctt
    89341 gtctctcttg tcagatccag ttcttgccaa ccatactcgt ggaaatatcc aagaggtcgc
    89401 agcccgtggt gccaaagtcc tcactatcgc agaagagaat gtagccaaag ataccgaaga
    89461 tatcgtcctt acgaccgtac atccatacct ctcaccaatt tcaatggtcg taccaacgca
    89521 attagtcgct tactttgcaa ccctccaccg tggcctcgat gtggacaaac cacgtaacct
    89581 tgccaagtca gtaacggtag aataagctaa aaaagtctag ttatctaggc ctttttcttg
    89641 tgagcaaatt ggttgcttgt actcaagatt cgtgttatac tcttcgaaaa tctcttcaaa
    89701 ccacgtcaac gtcgccttgc cgtaggtatg gttactgact tcgtcagttc tatccacaac
    89761 ctcaaaacac tgttttgagc agcctgcagc tagcttccta gtttgctctt tgattttcat
    89821 tgagtattag aataattttt caaattgaag tacagagata gataaggaga atcacaatgg
    89881 tagaattggg aatttcaaca tttggggaaa taacggagct tgaagggact ggacaaactt
    89941 acagtcatgc tgaacgcatt cgccagttgg tggcagagat tgagctggct gacaaggttg
    90001 gtttggatgt atatgggatt ggtgagcacc atcgggcgga ttttgcagta tcagccccag
    90061 agattgttct ggccgctggg gcagtcaata ccaagaaaat ccgtttgacc agtgcagtca
    90121 gcattctgtc aagcatggac ccgattcgtt tgttccaaca gtatgccact atcgatgctt
    90181 tgtcaaatgg acgagcggag attatggctg gaaggggctc tttcacggaa tctttccctc
    90241 tgtttggtta tgacttgaaa gactacgact ctctttttga tgagaaatta gacttgcttc
    90301 agttagtcaa tgaaaagacc aagttagact ggcaaggtcg attgactcaa acgattgctg
    90361 gtaaagaagt ttatcctcgt ccagttcagg acaaattgcc cttgtggata gctacaggtg
    90421 gtcatgtcga atcaacagtg aagattgctc aggctggtct accgattgta tatgctatta
    90481 ttggtggtaa tccacgttat tttaaaaagt tgattcaggc ttatcgtgag attggaagcg
    90541 aagcgggtca tgctgacaaa gacttgaaag tgggagccca ttcttggggg tggattgcgg
    90601 aagatggtga gcaggcggtg aaagattatt tccatccgac taagcaagtg gtggatgcta
    90661 tttccaaaga ccgtccgcac tggcaggaat tgcgttatga gcaatatttg gagcaggtag
    90721 ggccaaatgg cgccatgttt gttggcaatc cagatcaggt ggccgaaaaa ttgattcgca
    90781 tgatagagga tttaggattg gaccgcttca tgcttcatct accgcttggt tctatgcctc
    90841 atgaccaggt tctgagagct attgaactct tcggaacaca agttgcaccc aaagtacgag
    90901 cttattttgc tatgaaagag gcttaataaa aaatcctaat caagtttatt aggacaacaa
    90961 atattgtacg aaaattaatc ccccgagcta taatgcttgg gggatttttc tataggaggg
    91021 ctagtttagt tctctttttt attttttagt aagaaaccga gaccaaggag cgcaaggagg
    91081 ctgattcctg caaataggag tttgttttcg tttttgattc ctgtatttgg aagttcagct
    91141 tgtctatctg gggttgcagg tatatttttc ttgctagagt tttctaccga ttcgttttga
    91201 accgcttctt ttacagatga tgcttgtgct tcttgtgctg gttgttcagc ttgtgaatca
    91261 gctgtagctt ggctaggttt attttccgca tcagctactt tggcatctgg tttagtagaa
    91321 tcaggtctag cttctggagc tgggtcttga tgtgcagggt gagaagcttc attttgatgt
    91381 tcaggcttgg aaggggttga gtctggtttc tctgctgcag ttgactcatg gctagttcca
    91441 ttttgagaga ctcgaagaac agtagctgta agggcattca atttcaagcc tttttcagtc
    91501 cattcaagtc ctttcgggtt ggcaattccg actggtcctg cttggttttc atctgccaaa
    91561 acttccgcat ttcttagatg tgcaaaggca gttcccaaat taaattcgcg agctttttca
    91621 tccgcattga caaagactgc gtagatatcg ccgtttggag cagtgatttg gtagccaatc
    91681 actacatcct ctttttccac accattttgg cctgggacag tgatgaggtg gacacggtct
    91741 ttgatatctt gaagactctt aagtcggaag gcatctgtag attgacgaag ggcaatcaaa
    91801 cctttcatat agtcacggct cttgacattt tcaggataag ctttaccatc tgtagcctta
    91861 gtccagtcaa acttgttgac tgcatcgcta gaatcgtaag aatcatggat gaagtaagga
    91921 tagtcaaatg ggttgccgtc cttatcacgc aacaagtgag atttgtttgg aaccttatcc
    91981 tctgctactg gagtcttgta ggctgggtca cggaattgtt tagtacgtcc atattcctga
    92041 ccggagtgga taaatggagt tccttgagct gtcaagacca tgagatttcc aagtcgtaaa
    92101 cgacggtgga tttcagcata gttctcagcc ttgcttgggt cttttttgat agactgggca
    92161 atgatgtcaa agagggtcaa gttatcatgg gctgcgatgt attggatgac atctccaggg
    92221 ctgtcagctt caaagttagt tggttgagca atgagatttt taaagatggt gttgacatca
    92281 cgcttgccac ctgtgataaa ggcaggttga ccttcgtttg gataaccaga tttgaggttg
    92341 ttacggatgt catctgaaaa gacagcgaca gtatcggtat gtttcatcca atcttggtca
    92401 gcagctttag taggcatgtt ttcatcaccg gcataggttc tccaaccttc gcctaacatg
    92461 attagatttg gattgagggc gcgtgcagcc ttgtaagctt cttcgataga agcggcgtca
    92521 tggtctccca tcatatcgaa gcggaagcca tccactttgt aggtatcaac taggtatttg
    92581 atagagtcaa ctaggagccg tttggtcata tggtgggttg tccccaagcg tccaccacca
    92641 aagctagttc gaggtgtgcc atcggcatcc ataaagtggt agtagtttgg ctctaggtct
    92701 tcaaagatat cgactttggc tgtgtggtta taaacgacat ctaggatagc tcccatacca
    92761 cgtttgtgga tttcgttgat gaggttttta aattctgcga ttcgtttttc tggattctta
    92821 ggatcgcttg agtacatacc agtcaaggag aagtagtttt gagggtcata tccccagttg
    92881 tagttgctgt tgcttgaagc atagtcagac aagcgttcat ggtttttcaa ttcattgaca
    92941 aagtagtaag acaagactgg aaggagctgg atatgggtta cacccaagtc tttgagatag
    93001 tctagttttt caatgaaggc ttcaaaagtc ccaaatggtt tggtcaagtc ttttgcaatg
    93061 gcaggatctg aagtgaagtc acgcacatga gcttcgtaga taacggcgtc ttcacgagtc
    93121 ttgaaattgt gaatcttacc ataagtcaag tcttgaggtc cgagtttagc tggatctaca
    93181 aaggcggctt tagccacttt atgggcatcg tcaatcttgg catcgtcgct attccaagca
    93241 gcaagagatt tagcgtaagg atcgagtgca agaacagttt taccttgacg ctcgatttgg
    93301 tattgataat agtagccagt gaaatctgtg attccgagtt tgtttgtgct gtctagagtt
    93361 tgtttccaag ttcctctttc ccctttttcg agagcgacag ttccaactac tttgtcaggg
    93421 tcattcttgt cgtagacaac aacagaaacc ttatcagcac ttggtgacca aagggtcaaa
    93481 tcaacttgtt ttccttcttc ttttaggtca gctcccagtt tgccatcata gctgtatgtc
    93541 tcatctttca ggcgccagct tgttttggta gtgaattggt cggaattgta gctaacagta
    93601 taaggatgtt ttgtgtcaga gaaatctccg ctgtaggtca ctttcttacc agcttcatcg
    93661 attgcaacat cggtaatagt taccttgttt cctaggtgat tagtgatgtt ggagtgtttg
    93721 aggatatctt cttttttagc accgacaagt gttgaaaagc tactttcaat gctagaagtg
    93781 cctacgtgtt gggctcctgt catacggata tcatggacat agtatggatt tgtgtaaatc
    93841 gattcatcat cgtcttttag gaaaatttgg ctatgatttt tcaaatctgt gaacttataa
    93901 ttttctttac ggattttcac gtcgtctcct tgtttgctct catctagtaa taaaaatcca
    93961 aattctcttg cggcttcatt aagaggaatg tcgatatagc ggccatattt gcctgtagcc
    94021 gtaaagtctg ttccgtcagg ccattgagcg ctacttggat tttttacatc tccccagtac
    94081 cagagagatt tcttgtcata gttgccatct gtgcggtagt agttgacgcg aacagttcct
    94141 gcaggctgtg gctcgtaaga gaaaaccttg taatcttggt ctaaccaagc ttcgttcatt
    94201 tttggaacta gtttttctac agatttatcg ccggttagat tttttccagc tgtattgttg
    94261 atgaggaagc taattttctt ggcttgttct ccctttaatt tgacatctag gtaatagccg
    94321 tagtcatctt tcttggcatc cttgaaggac aaagctccgt ttggccagtt ttcagatggt
    94381 ttttcaacat cgtcccaagt ccatagtcct tgagcatcct tgttttcttc aggaagtttt
    94441 ttgacatgga tacggaagta gttatcttcg atgggctctt ctgccttagt ttcagttgtt
    94501 actggactag tagaagtagt tggctcactt gaacgatctt gtccagtttg tggtgctgga
    94561 tcggctgggc ttgcagcagg tttttcttct gttttctcta gggaagcgtt tgcatttcta
    94621 ggtgaagaaa tatcactttc gttcttacca gagccagctg ctgtatcagt aagaggttgg
    94681 gcaagggtgg ttgtatttct gttgttgggt tcgttagtgg ttggtgtact ttcgtcggat
    94741 gagatagttg gtgtagccat ggcaagcaag acaaggcttg cgccgataag gacagaacca
    94801 gttccatttt tgagggaacg gatgctgtag accatttttt tctcagtgtg agatggtgtt
    94861 tttctcataa tgattctcca atcaataaat ttctatatca gtatagcatg tagtaaaaca
    94921 atatgcgagc gttttctttg atttgtgaaa aaaattccta cttttgagaa gttttctgta
    94981 ctattttata tatcagtata aatgacggag ataaaaatgt cacataagcc aagccgtatt
    95041 attagggaga tgatgtgtta ccagctattt ttattcagaa attgatctct aacattacca
    95101 ataaaaaaga aaaatatctt gacaagcaag ggaaaatttt gttacaataa tagacggtac
    95161 tttttacttt tggtctctca agagtgtaca gggacgtgct gacaaatgtt gcaaaagtac
    95221 acacagatga tatctgtcac caagtgtatc atcaccaaaa ataaaaaaac acaggagaat
    95281 gtagatgcct acaattaacc aattggttcg caaaccgcgt aaatcaaaag tagaaaaatc
    95341 taaatcacca gctttgaacg ttggttacaa tagtcataaa aaagttcaaa caaacgtttc
    95401 ttcaccacaa aaacgtggtg ttgcaactcg tgttggaaca atgacaccta aaaaacctaa
    95461 ctcagccctt cgtaaattcg ctcgtgtacg tttgagcaac cttatcgaag ttactgccta
    95521 catcccaggt atcggacaca acttgcaaga gcacagcgtg gtgcttcttc gcggtggacg
    95581 tgtaaaagac cttccagggg tacgttacca tatcgtccgt ggtgcacttg atactgcagg
    95641 tgttaacgat cgtaaacaag gccgttctaa atacggtact aaacgtccaa aagcataagg
    95701 aaaggggata aagagaaatg agtcgtaaaa atagagctcc aaaacgtgac gtattgccag
    95761 atccgctata caattcacaa ctagttactc gtcttatcaa ccgcgttatg cttgatggta
    95821 aacgtggtac tgctgcttca atcgtttacg gtgcttttga gcaaatcaaa gaagctactg
    95881 gcaacgatgc acttgaagta tttgaaacag ctatggaaaa catcatgcct gtacttgaag
    95941 tacgtgcacg tcgtgttggt ggttctaact accaagtccc agttgaagtt cgtccagaac
    96001 gtcgtacaac acttggactt cgttggttgg taacaatcgc tcgtcttcgt ggtgaacaca
    96061 caatgcaaga ccgtcttgca aaagaaatct tggatgctgc taacaacact ggtgcagctg
    96121 ttaagaaacg tgaagatact caccgtatgg ctgaagctaa ccgtgcattc gcacacttcc
    96181 gttggtaaga taggatgcga aagcgttaag aaagtcccag agaaaatagg gaatcgaagc
    96241 aggttgcggt tgcaaccaat gagattcatc tttttctcca gacttttagc ttgagctcaa
    96301 ctaaatcatg atgctaggca cggtaaggat gcaaggtgaa aataggaaac tgacgcagta
    96361 ttcgatgaat acaaggagtt ttatcttttt cacgcagcat cccgttccag ctcatatcgg
    96421 ctaactaact ttagcccggg ttcaaattag ctaaatcgat tagtattagc tataactcag
    96481 cttaccatct cgtaagttga aaccaacaat agcatgaaaa cattgagaac gggtaggtcc
    96541 tgcctatccg tttttattaa aatcgtgtta taatagaata gaaatcaaaa ataaatagga
    96601 gaaacaaacc tcatggcacg cgaattttca cttgaaaaaa ctcgtaatat cggtatcatg
    96661 gctcacgtcg atgccggtaa aacaacaact actgagcgta ttctttacta cactggtaaa
    96721 atccacaaaa tcggtgaaac tcacgaaggt gcgtcacaaa tggactggat ggagcaagag
    96781 caagaacgtg gtatcacgat cacatctgct gcgacaacag ctcaatggaa caaccaccgc
    96841 gtaaacatca tcgacacacc aggacacgtg gacttcacaa tcgaagtaca acgttctctt
    96901 cgtgtattgg atggtgcggt taccgttctt gactcacaat caggtgttga gcctcaaact
    96961 gaaacagttt ggcgtcaagc aactgagtac ggagttccac gtatcgtatt tgccaacaaa
    97021 atggacaaaa tcggtgctga cttcctttac tctgtaagca cacttcacga tcgtcttcaa
    97081 gcaaatgcac acccaatcca attgccaatc ggttctgaag atgacttccg tggtatcatt
    97141 gacttgatca agatgaaagc tgaaatctat actaacgacc ttggtacgga tatccttgaa
    97201 gaagacatcc cagctgaata ccttgaccaa gctcaagaat accgtgaaaa attgattgaa
    97261 gcagttgctg aaactgacga agaattgatg atgaaatacc tcgaaggtga agaaatcact
    97321 aacgaagaat tgaaagctgg tatccgtaaa gcgactatca acgttgaatt cttcccagta
    97381 ttgtgtggtt cagccttcaa aaacaaaggt gttcaattga tgcttgatgc ggttatcgac
    97441 taccttccaa gtccacttga catcccagca atcaaaggta ttaacccaga tacagacgct
    97501 gaagaaattc gtccagcatc tgacgaagag ccatttgcag ctcttgcctt caagatcatg
    97561 actgacccat tcgtaggtcg tttgacattc ttccgtgttt actcaggtgt tcttcaatca
    97621 ggttcatacg tattgaatac ttctaaaggt aaacgtgaac gtatcggacg tatccttcaa
    97681 atgcacgcta acagccgtca agaaatcgac actgtttact caggtgatat cgctgctgcc
    97741 gttggtttga aagatactac aactggtgac tcattgacag atgaaaaagc taaaatcatc
    97801 cttgagtcaa tcaacgttcc agaaccagtt atccaattga tggttgagcc aaaatctaaa
    97861 gctgaccaag acaagatggg tatcgccctt caaaaattgg ctgaagaaga tccaacattc
    97921 cgcgttgaaa caaacgttga aactggtgaa acagttatct caggtatggg tgaacttcac
    97981 cttgacgtcc ttgttgatcg tatgcgtcgt gagttcaaag ttgaagcgaa cgtaggtgct
    98041 cctcaagtat cttaccgtga aacattccgc gcttctactc aagcacgcgg attcttcaaa
    98101 cgtcagtctg gtggtaaagg tcaattcggt gatgtatgga ttgaatttac tccaaacgaa
    98161 gaaggtaaag gattcgaatt cgaaaacgca atcgtcggtg gtgtggttcc tcgtgaattt
    98221 atcccagcgg ttgaaaaagg tttggtagaa tctatggcta acggtgttct tgcaggttac
    98281 ccaatggttg acgttaaagc taagctttat gatggttcat atcacgatgt cgactcatct
    98341 gaaactgcct tcaagattgc ggcttcactt tcccttaaag aagctgctaa atcagcacaa
    98401 ccagctatcc ttgaaccaat gatgcttgta acaatcactg ttccagaaga aaaccttggt
    98461 gatgttatgg gtcacgtaac tgctcgtcgt ggacgtgtag atggtatgga agcacacggt
    98521 aacagccaaa tcgttcgtgc ttacgttcca cttgctgaaa tgttcggtta cgcaacagtt
    98581 cttcgttctg catctcaagg acgtggtaca ttcatgatgg tatttgacca ctacgaagat
    98641 gtacctaagt cagtacaaga agaaattatt aagaaaaata aaggtgaaga ctaatccgtc
    98701 ctcactctag aaggaagtca cttagtggct tccttttgtc tttagaaaat acctctaaat
    98761 atggtaaaat agtagaagaa taatgtgagg aaaatgaatg tcaaatagtt ttgaaatttt
    98821 gatgaatcaa ttggggatgc ctgctgaaat gagacaggct cctgctttag cacaggccaa
    98881 tattgagcga gttgtggttc ataaaattag taaggtatgg gagtttcatt tcgtattttc
    98941 taatatttta ccgattgaaa tctttttaga attaaagaaa ggtttgagcg aagaattttc
    99001 taagacaggc aataaagctg tttttgaaat taaggctcgg tctcaagaat tttcaaatca
    99061 gctcttgcag tcctactata gggaagcttt ctctgaaggt ccatgtgcta gtcaaggttt
    99121 taagtccctt tatcaaaatt tgcaagttcg tgctgagggt aatcagctat ttattgaagg
    99181 atctgaagcg attgataagg aacattttaa gaagaatcat cttcctaatt tagccaaaca
    99241 acttgaaaag tttggttttc caacttttaa ctgtcaagtc gagaagaatg atgtcctgac
    99301 ccaagagcag gaagaggcct ttcatgctga aaatgagcag attgttcaag ctgccaatga
    99361 ggaagcgctc cgtgctatgg aacaactgga gcagatgaca cctcctccag cggaagagaa
    99421 accagtcttt gattttcaag cgaaaaaagc tgcagctaaa cccaagctgg ataaggcgga
    99481 gattactcct atgatcgaag tgacgacaga ggaaaatcgt ctggtatttg aaggggttgt
    99541 ttttgatgtg gagcaaaaag tgactagaac aggtcgtgtt ttaatcaact ttaaaatgac
    99601 ggactatact tcaagttttt ctatgcaaaa gtgggttaaa aacgaggaag aggcccagaa
    99661 gtttgacctc atcaagaaga attcttggct ccgagttcga gggaatgtgg agatgaataa
    99721 cttcacacgc gatttgacta tgaacgtaca ggatctgcag gaagttgttc actatgagcg
    99781 gaaggatttg atgccagaag gtgagcgtcg ggttgagttt catgctcata ctaacatgtc
    99841 gactatggat gctttgccag aggtcgaaga gattgttgca acagctgcta agtggggaca
    99901 caaggcggtt gctatcacgg accatgggaa tgtccagtcc tttccacatg gctataaggc
    99961 ggctaagaaa gcgggaatcc agctgatcta tggaatggaa gccaatatcg tggaggaccg
   100021 tgtccctatc gtctataacg aagtggagat ggacttgtca gaagcaacct acgtggtctt
   100081 tgacgtggaa acgacgggac tttcagctat ctataatgac ttgattcagg ttgcggcctc
   100141 taagatgtac aaggggaatg ttattgctga atttgatgaa tttatcaatc ctgggcatcc
   100201 cttgtcagct tttactacag agttaactgg aattacagat gatcatgtca aaaatgccaa
   100261 accactagaa caagttttgc aagaattcca agaattttgc aaggatacgg tcctagttgc
   100321 ccacaatgct acctttgacg ttggctttat gaatgctaat tatgagcgtc atgatcttcc
   100381 aaagattagt cagccagtta ttgatacgct ggagtttgct agaaacctct atcctgagta
   100441 taaacgccat ggtttggggc ctttgaccaa gcgttttggt gtggccttgg aacatcacca
   100501 catggccaac tacgatgcgg aagcgactgg tcgtctgctt ttcatcttta tcaaagaggt
   100561 agcagaaaaa catggtgtga ccgatttaga tagactcaac attgatctaa tcagtccaga
   100621 ttcttacaaa aaagctcgga tcaagcatgc gaccatctat gtcaagaatc aggtaggtct
   100681 aaaaaatatc tttaagctgg tttccttgtc taataccaag tattttgaag gagtgccacg
   100741 gattccgaga acggttctag atgcccatcg agagggcttg attttaggtt cagcctgttc
   100801 agagggtgaa gtttttgacg tggtcgtttc tcaaggtgtg gatgcggcgg ttgaggtggc
   100861 caagtattat gactttatcg aggtcatgcc accggctatc tatgcgccct tgattgccaa
   100921 agagcaggtc aaggatatgg aggaactcca gaccattatc aagagtttga tagaggttgg
   100981 agatcgcctt ggcaagcctg ttctggctac gggaaatgtt cactatatcg aaccggaaga
   101041 agagatttat cgtgaaatta tcgtccgtag tttgggacag ggtgcgatga ttaaccgaac
   101101 tatcggtcat ggtgaacatg cccaaccagc gccacttcca aaggctcatt ttcgaacgac
   101161 taatgagatg ttggatgaat ttgccttttt gggagaggaa ctggctcgta aactggttat
   101221 tgaaaacacc aatgccttgg cagaaatatt tgaacccgtt gaagtcgtta agggtgactt
   101281 gtatacgcct ttcatcgaca aggctgaaga aacagttgct gagttgacct ataagaaagc
   101341 ttttgagatt tatgggaatc cgctgccaga tattgttgat ttgcggattg aaaaagaatt
   101401 aacatccata ctggggaatg gatttgctgt gatttatctg gcatcgcaga tgctggtgca
   101461 acgttctaat gaacggggtt atttggttgg ttctcgtggg tctgtcggat ctagtttcgt
   101521 tgcgaccatg attgggatta cggaggtcaa tcctctctct cctcactatg tctgtggtca
   101581 gtgtcagtac agtgagttta tcacagatgg ttcgtacggt tcaggatttg atatgcccca
   101641 taaggactgt ccaaactgtg gtcacaaact cagtaaaaac ggacaggata ttccgtttga
   101701 gaccttcctt ggttttgatg gggataaggt tcctgatatt gacttgaact tctcgggaga
   101761 agatcagcct agcgcccact tggatgtgcg tgatatcttt ggtgaagaat atgccttccg
   101821 tgcgggaacg gttggtacgg tagctgccaa gactgcctat ggatttgtca agggttacga
   101881 gcgagattat ggcaagtttt atcgtgatgc agaggtggaa cgcctcgctc aaggagcggc
   101941 gggtgtcaag cggacaacag gccaacaccc ggggggaatc gttgttattc cgaactacat
   102001 ggatgtctac gattttacgc ctgtccagta tccagcagat gatgtcacgg ctgaatggca
   102061 gaccactcac tttaacttcc acgatatcga tgagaacgtc ctcaaactcg atgtactggg
   102121 acatgatgat ccgaccatga ttcgaaaact tcaggatttg tctggtattg accctaatga
   102181 aattcctatg gatgacgaag gcgtgatggc actcttttct gggactgatg tgctaggggt
   102241 aacacctgaa caaattggaa cgcctacggg tatgttgggg attccagagt ttggaacaaa
   102301 tttcgtacgt ggaatggtag acgaaaccca tccgacaacc tttgcggaat tgcttcagct
   102361 gtctggtctg tcacacggta ctgacgtttg gttggggaat gctcaggatc tgattaagca
   102421 aggaatagcg gacctatcga ctgttatcgg ttgtcgggac gacatcatgg tttacctcat
   102481 gcatgcgggt ctggaaccta agatggcctt taccattatg gaacgggtac gtaagggttt
   102541 gtggctaaag atttcagaag aggagagaaa tgactatatc gaagccatga aggctaataa
   102601 ggtgccagag tggtatatcg aatcctgtgg gaaaattaag tacatgttcc ctaaggccca
   102661 tgcggcagcc tacgttatga tggccttgcg tgtagcttac ttcaaggttc accatcctat
   102721 ttattactac tgtgcttact tctccattcg tgctaaggct tttgatatca agaccatggg
   102781 tgcgggcttg gaggtcatca agcgcagaat ggaagaaatc tctgaaaaac ggaagaacaa
   102841 tgaagcctct aatgtggaaa tcgatctcta tacaactctt gagattgtca atgaaatgtg
   102901 ggaacgaggt ttcaagtttg ggaaattaga tctctactgt agtcaggcga cagagttcct
   102961 catcgacggg gataccctta tcccaccatt tgtagcaatg gatggtctgg gagagaacgt
   103021 tgccaagcaa ctggtgcggg cgcgtgaaga gggagaattc ctctctaaaa cagaactacg
   103081 caagcgtggt ggactctcat caaccttggt tgaaaagatg gatgagatgg gtattcttgg
   103141 aaatatgcca gaggataacc agttgagttt gtttgatgag ttgttttaaa aaattgctta
   103201 ataatctatt aaaagaggct aacgtatatc caatagattt acattagctt tcttttttgt
   103261 taaaatagtc tatggaaaga gggtgagagt atgtcaaaga tgagtataag catccgtctg
   103321 gatagtgagg ttaaggagca ggcccaacag gtgtttagta atctgggaat ggatatgaca
   103381 acagctatta atattttcct tcgtcaggca attcaatatc agggattacc ttttgatgtt
   103441 agactagacg aaaatcggaa gttgctccaa gtgttaacgg atttagacca aaatcgtaat
   103501 atgagccagt cttttgaatc agtctcagat ttgatggagg acttacgtgc ttaagattcg
   103561 ttatcataaa cagtttaaaa aagattttaa gttggctatg aagcgtggtt tgaaggcaga
   103621 attattagaa gaagttttga attttctggt tcaagaaaaa gaacatcctg ccagatatcg
   103681 tgatcattca ttgacggcat ccaagcattt tcaaggagtt cgtgaatgcc atacccagcc
   103741 agattggctt ttggtttata aagtagacaa gtcggaattg attttaaatt tgctgaggac
   103801 aggcagtcac agtgatttat tttaatctat tttaaggggg ttctcatgaa actaagaata
   103861 tttgcggaag ataagccggc taagaaggta tttgaatatc aattagaact tgctgatcgt
   103921 acaattcttc tatcaacagc actcttgtca ggtgctattg ctttagcggg attattctct
   103981 gctttgaaag aaaaataaaa atagaaaaga gaaaattaca tggttttacc aaattttaaa
   104041 gaaaatctag aaaaatatgc gaaattattg gttgcgaatg gaatcaatgt gcaacctggt
   104101 cacactttgg ctctctctat tgatgtggag caacgtgaat tggcacatct aatcgtgaaa
   104161 gaagcttatg ccttgggtgc gcatgaggtc atcgttcagt ggacagatga tgtgattaac
   104221 cgtgagaaat tcttccatgc cccgatggag cgtttggaca atgtgccaga atacaagatt
   104281 gctgagatga actatctctt ggagaacaag gctagccgtc ttggagttcg ttcatctgat
   104341 ccaggtgcct tgaacggagt ggacgctgac aagctttcag cttctgctaa agctatggga
   104401 cttgccatga agccaatgcg aatcgcaact caatctaaca aggttagctg gactgtagca
   104461 gccgctgctg gacttgagtg ggctaagaaa gtcttcccaa atgctgcgag cgacgaagaa
   104521 gcagtcgatc tcctttggga ccaaatcttc aaaacttgcc gtgtctacga agcagatcct
   104581 gttaaggcct gggaagagca tgcagccatt ctcaagagca aggccgatat gcttaataag
   104641 gagcaatttt cagcccttca ctacacagcg ccaggaacag atttaacact tggtttgcca
   104701 aagaaccacg tttgggaatc agctggtgct gtcaatgcac agggcgaagg attcttgcca
   104761 aatatgccga cagaagaggt cttcacagcg cctgacttcc gtcgtgcaga tggttatgtc
   104821 acttctacaa aaccgcttag ctacaacgga aatatcattg aaggcattaa ggtgatcttt
   104881 aaggatggac aaatcgtaga tatcactgct gagaagggtg atcaggttat gaaagacctt
   104941 gtctttgaaa atgcgggtgc gcgtgccttg ggtgaatgtg ccttggtacc agatccaagt
   105001 ccaatttctc agtcaggcat taccttcttt aacacccttt tcgatgaaaa tgcgtcaaac
   105061 cacttggcta tcggtgcagc ctatgcgact agcgttgttg atggagcgga gatgagcgaa
   105121 gaggagcttg aagctgcagg gcttaaccgt tcagatgttc acgtagactt tatgattggt
   105181 tctaaccaaa tggatatcga tggtattcgt gaggatggaa cgcgggtacc tcttttccgt
   105241 aatgggaatt gggcaaatta aggagataat atgttaggaa gtatgttcgt tggtctccta
   105301 gtgggatttt tagcaggtgc tatgaccaat cgtggagagc gaatgggatg ttttggaaaa
   105361 atgtttctcg gttggatcgg agcctttcta ggtcacttgc tctttggaac ttgggggcca
   105421 gttttatcag gaacagctat tatcccagct gttttaggtg ccatgattgt cttagctatt
   105481 ttttggagac gaggaagtta atttcctaaa tctgatactc aatgaaaatc aaagagcaaa
   105541 ctaggaaact agccgcaggt tgctcaaagc actgctttga ggttgcagat agaactgacg
   105601 aagtcagtaa catatatacg gcaaggcgac gttgacgcgg tttgaagagt atgaaacgaa
   105661 aaggaggttg gtcattgtac cagcctcctt ttgatatgat ataatagttc tatgagatta
   105721 gataaatttt tagttgcctg tgcggtggga agtcggactg aggtcaaaaa cttgctcaag
   105781 gctgggcgag tgactgtaaa tggtaaaaaa gaaaaatcag ctaaattgca gattgatgaa
   105841 aaaatagatg agattcgctt tgatgggcaa gtgttggagt atgaagagtt tgtctactac
   105901 atgatgaaca agcccaaagg agttatctca gcgactgagg atcccaagca cagaaccgtt
   105961 ctggacttgt tggatgactt ggcgcggagt aaggaagttt tcccagtagg acgcttggat
   106021 attgacacgc atggtctttt gcttttgacc aatgatggtc agctggctca tgttcttctt
   106081 tcgcccaagc gtcatgtgga caagacttat ctggcacaag tcaagggaat catgacccaa
   106141 gaagatgtgg agacatttgc tgagggtatt cctctcaaag actttacctg tcaacccgct
   106201 atactggagc ttgtatccat agatacagaa aagaatcaaa gccaaatccg tgtgaccatt
   106261 gcagaaggga agtttcatca gatcaagcgt atggtgggct actgtggcaa ggaagtggtg
   106321 gacttgcaac gattgactat gggaacttta gtattagatg agaacctgga acgaggggaa
   106381 tggcgtcgct tgaccaagga agaattagaa attctccgcg ctaatattat ttaatttagt
   106441 ttaatactca atgaaaatca aagagcaaac taggaaacta gccgcaggct gtacttgagt
   106501 acggcaaggc gacgttgacg tggtttgaat ttgattttcg aagagtataa attcgaaaaa
   106561 ggtgagggac aatgtcctcg ccttttatgt tttttagttg cttcctttgt gaaaagagtt
   106621 ataatagact gtagaataaa aggaggaatc tatgaacgcg attcaagaat catttactga
   106681 taaactattt gccaactatg aagcaaatgt aaaataccaa gcgattgaaa atgctgccag
   106741 ccacaacgga atttttgcag ctctggaatg tcgccaaagc catgtagaca acacacctgt
   106801 tttctcattg gatttaacca aggacaaggt cactaaccag aaagcgtctg gtcgttgctg
   106861 gatgtttgcg gctctcaaca ccttccgcca caaactcatc tcgcaataca aattggagaa
   106921 ctttgagttg tcacaagccc acactttctt ctgggataag tatgagaaat caaactggtt
   106981 cttggagcaa gtcattgcga cttcagacca agaattgact agccgcaagg ttagcttctt
   107041 actccaaaca cctcaacaag atggcggtca atgggatatg gtcgtttccc tctttgaaaa
   107101 atacggtgtc gtgcctaagt cagtttatcc tgagtctgtt tcatctagca gcagtcgtga
   107161 gctaaatgcg atccttaata aattgcttcg tcaagatgct caaatcttgc gtgatttgct
   107221 tgtttctggt gcagatcaag cgactgttca agctaagaaa gaagacctct tgcaagaaat
   107281 ctttaacttt cttgctatgt cattaggact tccaccacgc aagtttgact ttgcttatcg
   107341 cgataaagat aacaactata aaagtgaaaa aggaatcaca ccacaagagt tttacaagaa
   107401 atatgtcaat cttcctttag aagactacgt ttctgttatc aatgctccaa ctgctgataa
   107461 accttacgga aaatcttaca cagttgagat gttggggaat gtggttggta gccgtgcagt
   107521 tcgctacatc aacgttccaa tggagcgctt gaaagaattg gcgattgccc aaatgcaagc
   107581 aggtgagact gtttggtttg gttctgatgt cggccagctc agcaaccgta aggctggcat
   107641 ccttgcgaca gatgtttatg actttgaatc aagcatggac attaaactta ctcaagacaa
   107701 ggctggacgt ttggactata gcgaaagctt gatgacccac gccatggtct tgacaggtgt
   107761 tgacttggac gaaaatggta aatcaaccaa gtggaaggtt gaaaactcat ggggagacaa
   107821 ggtcggtaca gatggttact ttgttgcctc agacgcttgg atggacgaat acacatacca
   107881 aatcgttgtt cgtaaggaat tgctgacagc agaagaacaa gctgcctatg gagcagaacc
   107941 aatcgtactt gcaccatggg atccaatggg agccttggct gaataaaagc atagaaaaaa
   108001 ggaatcagat tttagaacct ggttcctttt tagttgcttg attacatgat gtgaagaaca
   108061 tgtgccacaa tacccactgc gaagagggca aggataatag tgattggaga tacttttttc
   108121 ttaagtaagt acatgcaaag taaagtaagg agtagtcctg ataatccagg aatcaacata
   108181 tccaagtttt gttggaaagt agtaactttt tcaggagttt gagacaatcc ttgtcctact
   108241 tgtgcgaatg cttcttggat acctttagac ccttctggca atttatccca atggatataa
   108301 gccttttcat ctagttgaac tttagaaaca tcgaaagcaa atttaatatt tacccaacgt
   108361 tgaacaagga cagcaagaat gaacatccca aggatagaag ctcctttagt gatatcttga
   108421 aggataccac cagacatatc tttagtgatt tctgatccag ccttgtatcc aatctcttga
   108481 acataccaca agaatgacat acgaatcaag ttccatgcaa caaagaagag gagtggcccc
   108541 aagatattgc cagtaagggc aagtgaagca ccgagagatc caaggattgg gcgtactgta
   108601 aaccagaata ctgggtcacc gataccagca agaggtccca tcataccgat tttaacccct
   108661 tggatagcag cgtcatcgat ttccacaccg ttagcacgtt cttcttcaag cgcaagagta
   108721 acccccatga ctggagcagc tacgtatgga tgagtgttga agaactcaag gtgacgctca
   108781 agagcagcga tttgatcttc ttttttagta tagagttttt tgatagctgg aatgagtgta
   108841 taagcccagc ccaagttttg catccgttca aagttccaag acccttgtaa gaaggttgaa
   108901 cgccaccaaa cttttttacg atctgattta gttaattgaa gtttttcagt catgatgttt
   108961 tcagtccttt cttatcttag tagtcttcta ggatatcgcc gattgggtcg ttagaagttg
   109021 cggctcctcc gccaccattt ccaccagttt tagaaaggtg aaggtagata agagcgatag
   109081 caacaccgat agcaccgaat ccgattagag taatatctga cacagcagcg agaacgaaac
   109141 caagagcgaa gaatggccat acttcacgag ttgccatcat gttgataacc atggcgtaac
   109201 caacggcaac gaccatacca ccaccgatag ccataccatc tttgagccag tctggcatgg
   109261 cactaaggat actttgtaca gtttcagttg gtaccataag gagaagagct gcaggaagcg
   109321 cgatacgaag tccttggaag agtagcgcaa tgaaatgcgc acgctccaca gcgccgaagt
   109381 cacctttttt agcggcagca tctgcagtat gaaccaaacc aactgaaatt gtacgaacaa
   109441 tcattgtcaa gaaaagtcca gctacggcaa gagggatagc aaccgcttgg gcaacaccga
   109501 taccagtctt ggtaaagtca ccaccaagaa ccatgataat ggcagcagcg acagaagcaa
   109561 gtgcagcatc aggagcgata gcagcaccga tatttgacca accaagggca atcatttgaa
   109621 gcgatccacc gaggataatc cctgcttcca agtgacctgt tacaagccca ataagggtac
   109681 aggctacaag tggttggtga aattggaact ggtcgaggat gccttcaaga cctgcaaaga
   109741 aggctacaac gactactaaa accatagaaa taatagacat gtttaaaatc ctttcataaa
   109801 taatggctta tttgacattg gctttgttaa tcaagtcaaa caaatctttt ttagaatcat
   109861 ttggtacttt acggacatca aattcaacac ccaagtcacg cattttttca aatgtagcaa
   109921 catcttcttt gtccatagac aaaacggtat tgaccaatgt tttacctgtt gagtgagcca
   109981 tagaaccaac gttaagagtc ttgattggca cgccgccttc gatggcacga agggcatctt
   110041 gaggtgtttc aaacaagata agggcatgtg tttctccaaa acgtgggtct tttgaaatct
   110101 caatcagttt ttgaattgga accacgttag ccttgacatt acctggagct gcttgtttaa
   110161 tcaattcttt acgaaggtcg tctttagcca cgttatctga agcaacgatg atacgatttg
   110221 cttttgaatc tggagtccaa gcagttgcaa cctgaccgtg aagtagacgt gtgtcaagac
   110281 gggcaagatt gattttcaat ttaccgtctc cgataacagt tccttctggg atagcagttt
   110341 gggcaactgg agcagctgca gcgcttgcaa cttcttcaac tggatttagc tcttctggaa
   110401 gagctttgat gccatctttg gcttctttaa tgatattagc agcgactttt tctacacctg
   110461 cagcagcgtc catgaggcgc tctgtgtagg cttgaatcaa catcggtaag ttaagtcctg
   110521 tgatgatggc aaacttacgc tcaggatttt ctcccattac gcgactagct tggttaaatg
   110581 gagaaccact ccaaaggtca gccaaaacta gaacctcatc ttctgcgtca aatgcagcaa
   110641 cagcgttatt aaacttagcg tatagatcat caggaccttc atttggcata aaggtcacaa
   110701 cttgaacctt ttcttgttca ccaaagatca tagatcctga ctgatgaata cccgcagcaa
   110761 attcgccgtg gctcgcaata atgattccga tactcattat tgtcattcct ccttttttgt
   110821 tttagttttc atttaagaaa actttaagac tgtttaagta taaaccgttt tcataaaaaa
   110881 agcaactatt tatcataaaa aattaaaaaa tttttatttt tgtatgttga tatgttgagt
   110941 ttttgaggag taatcttgaa ttcttattta aaaatttaat ataaaaaagt tggaagaagc
   111001 ttccaacttt taaaataggt ttctattaga ttagtgggtg aagtcgagta ccatacgtcc
   111061 ttggatttga cctttttcca tttcgtcgaa aatggcaaca gcatcttcta ctggacgttt
   111121 ttgaacaact ggggctacca gaccttctgc accaaattgg aaggcttctt ctaagtcttt
   111181 acgagttccg acaagagaac cgatgacttg gattccatcg aggactgttt taacgatgct
   111241 gagttccatc atttcagaag gaagaccaac agcgacgacg cgaccaccag cacgaacgga
   111301 gtcaacagcc tggttgaagg caactttaga cacagcagtt acgacagctg aatgagctcc
   111361 tccatcagtt ttttctttga tgagtccagc tacatcttca acttcgaggc cgttaatcac
   111421 aatgtcagcg cctacttctt ttgcaagggc aagtttgtca ttgttgatat cgactgcgat
   111481 aacatgagca ttgaatactt ttttagcgta ttgaacagcg aggttaccaa gtccaccagc
   111541 accgtaaaga acaacccatt ggcctggttc aacttttgct tctttgatag ctttataggt
   111601 tgttactcca gcacatgtga tagaagaagc ttgggctgga tcaagtccgt caggaacctt
   111661 gacagcatag tcagcagtta cgatacattg ttcagccata ccaccgtcta ctgagtagcc
   111721 agcatttttc actgtacggc aaagggtttc gcgaccagtt gtacagtatt cgcaagtgcc
   111781 acatccttca aagaaccaag caacgctgac gcggtcaccg actttaaggc ttttcacatc
   111841 tggagcaatc tctttaacga taccgatacc ttcgtgccca agaacacgtc ctgggacttg
   111901 accaaagtca ccatgagcaa cgtggaggtc ggtgtggcaa acgccacagt attcaacttc
   111961 tacaagtgct tccccagttt caagtggacg gagtactttt tcttcaatag caacaccagt
   112021 gctttctgga tttacaacaa cagctttcat agctatcctc cttgatattg accgagaaca
   112081 gggacaacgg gactggattg attttttgtc aacagagtcg agtgtgacga gctctcttgt
   112141 atttatatgt gaagtatatc acaaaagaaa gccttttcca aggttttgga gacaaaaagt
   112201 agaacaatcg attaactggt tgatgagact gtgaaaagag cacaaagacc agcttgcaag
   112261 ctggtcatac tcttcgaaaa tctcttcaaa ccacgtcagc ttcatctaca acctcaaagc
   112321 agtgctttga gcaacctacg gctagcttcc tagtttgctc tttgattctc attgagtatc
   112381 agtataggtt ataagaataa gtcttgtagg gttttggcaa ccccatcttg gtcgttggta
   112441 agggaaattt gctcatctgc ataagggagt agctctggat tggcattttt catggcataa
   112501 cccttcccag caaaagcgag catttcggta tcattgtgtt catctccaaa ggcaatcaaa
   112561 tcttttttgt cacgattcat tatcttgagc aagtagtcca aagcaaaggc cttgttgaca
   112621 ccttttgggg tacattcaag gatattgagc ggacctcccc aggtattgat agaaagttga
   112681 tgctggtaga aggcgttcat gtcttttgcc aaggcatatt tgtcactggc tctggtctgc
   112741 aagaggatac agttagggtc cttggtcacc aattcaggct ggaattgatc ttcaggctgg
   112801 aaaacttcta caccaaatag tttgggattg gcaatttctt cattgggatt tgtaatgtag
   112861 aattttttac gatattctcc agcgataaaa tcggcttgaa tgtcctctga acgttgaacc
   112921 atatctagca gatatttttt gtctacagtc aaacactttt caaaatccca aacttggtct
   112981 ggtaaatgag taagggatcc gttgaagtta atcataggag tgtctaagcc cagttcacgg
   113041 taaaaatctt ttgacatacg gtaagggcga cctgtcgtaa taataacctg atggcctttt
   113101 tcagcaactt ttttgatggt ttttttggta aagtcagaaa tttgactgtc tgagttgagc
   113161 agggttccat ccaggtcaac tgcaataatt tttttcgtca tatggacctt tctagtgtgt
   113221 tttcagataa gatgtcttct attataacag aaagcaggca gaaaagcaga ttccaaacaa
   113281 aaaatgaaat tggattaatt tcttaaacaa atcaaacaaa gacattgaaa aagtgaataa
   113341 taaatgatat aattctatta ttgttcgtaa aaattaaaag gagattgatg atggacaaat
   113401 tatttaaact aaaagagaac ggtacagacg ttcgtacaga ggttctcgct ggtttaacaa
   113461 ctttctttgc aatgagctat attctctttg taaacccaca aatactttca caaacaggaa
   113521 tgcctgctca gggcgtcttc ctagcgacga ttattggtgc agtagcgggt accttgatga
   113581 tggcttttta tgctaactta ccttatgccc aagcgccagg tatgggactc aatgccttct
   113641 ttacctttac agttgtattc gggcttggtt attcttggca agaagcccta gctatggtct
   113701 tcatctgtgg gattatttca ttgattatta ccttgacaaa tgttcgtaaa atgatcattg
   113761 aatcgattcc caatgctctt cgctcagcta tttcagctgg tatcggtgtc ttccttgcct
   113821 atgtagggat taagaatgct ggacttttga aattcacgat tgatccaggc aactatactg
   113881 ttgtaggaga aggggctgac aaagctcaag caacgattgc agcaaactct tcagcagttc
   113941 caggattggt cagctttaat aatccagctg ttttagtggc tcttgcagga cttgccatta
   114001 ctatcttctt tgtcatcaaa gggattaaag ggggaattat tctctctatc ttgacaacaa
   114061 ctgttcttgc tattgcagtt ggtttggttg atttgtctag tatcgatttt gctaataata
   114121 accatgttgg tgcagctttt gaagatttga agacaatctt tggtgcagct cttggttcag
   114181 aaggtttggg agctttggtt tcagatacag ctcgcttgcc tgaaactctg atggccattc
   114241 ttgccttctc attgacagat atttttgaca caattggtac cttgatcggt acaggtgaaa
   114301 aagttggtat tgtagcgaca aatggtgaaa atcaccaatc agccaaattg gataaggctc
   114361 tttactctga tttgattgga acgacagtcg gtgccattgc aggtacttca aacgtaacga
   114421 cttatgttga gtctgctgct ggtatcggtg caggtggacg tactggtttg acagccttgg
   114481 ttgtagctat ctgttttgcg atttcaagct tctttagccc acttctagcg atcgtaccaa
   114541 cagcggctac agctccaatc ttgattatcg ttgggattat gatgcttggt agcttgaaaa
   114601 atatccattg ggatgatatg tctgaagcag ttcctgcctt cttcacatct atctttatgg
   114661 gattcagcta ctctatcact caagggattg cagttggttt cttgacttac actttgacta
   114721 agcttgtcaa aggtcaagtt aaagatgttc atgccatgat ttggattttg gatgccttgt
   114781 ttatccttaa ctacatcagc atggccttat aatagaatga cccaggggga ttttccccct
   114841 tttttaatac aaaggagata ggtgatgaaa gagaaaaata tgtggaaaga attgttgaat
   114901 cgtgcaggct ggattttggt ctttttactt gccgtccttt tatatcaggt tcccctagtg
   114961 gttacctcta ttttgacttt aaaagaagta gccctgctac agtcagggct gatagttgct
   115021 ggcctttcaa ttgtggttct ggctctattt attatgggag ctcgtaaaac caagttagct
   115081 agttttaatt tttctttttt tagagctaaa gatttggcac gtttgggctt gagttattta
   115141 gttattgtcg ggtcaaatat acttggttct atcttgttgc aactgtcaaa tgagacgaca
   115201 acagctaacc agtctcagat taacgatatg gttcagaata gttctctgat ttctagcttc
   115261 ttcttgctag ccttgcttgc tccaatttgt gaggaaatct tgtgccgtgg gcttgttcct
   115321 aaaaagattt tccgaggcaa ggagaacttg ggatttgtag tcggtacgat tgtgtttgct
   115381 ttattgcatc aaccaagtaa tttaccttct ttattgattt atggaggtat gtcgacagtt
   115441 ctatcttgga cggcctacaa gacccaacgt ttggaaatgt cgatcttgct tcacatgatt
   115501 gttaatggga ttgctttctg tttgttggct cttgtggtga ttatgagtcg gacattagga
   115561 atttctgtgt aaaagttttt atgtaggaac cgacctcttt ctactaggga aagatgaatg
   115621 caatcgtgtc catctttttc tttttatggt aaaatagaaa aataatatga tgaaaatcct
   115681 tgagggagtg accgatatgt caagtaaagc caatcatgca aagacagtta tttgcggaat
   115741 tatcaatgta accccagact ccttttcgga cggtggtaaa ttttttgctc ttgagcaggc
   115801 actccagcag gctcgtaaat tgatagcaga aggagccagt atgctcgata tcggcggaga
   115861 atcgactcgg ccgggcagta gctatgttga gatagaagag gaaatccagc gtgttgttcc
   115921 agtgatcaaa gcgattcgca aggaaagtga tgtcctcatc tctattgata cttggaagag
   115981 tcaagtagca gaggctgctt tggctgctgg tgccgatcta gtcaatgata tcactggtct
   116041 tatgggtgat gagaaaatgg ctcatgtggt agctgaagcg agagcgcaag tggtcatcat
   116101 gtttaatcca gttatggcgc gacctcagca ccctagctcg ctcatcttcc ctcattttgg
   116161 ttttggtcaa gcttttacag aggaagagtt agctgacttt gaaacattgc caatcgaaga
   116221 attgatggag gctttctttg aacgagcact agcgagagcg gcagaagctg gtattgcacc
   116281 agaaaatatc ctgttggatc caggaattgg ctttggtctg accaagaaag aaaatctgct
   116341 tcttttacgg gacctggata aactacatca gaagggctat ccaatctttc tcggagtgtc
   116401 gcgcaagcga tttgtcatca atatcctaga ggagaatggt tttgaagtca atcctgagac
   116461 agagcttggt ttccgaaatc gggacacggc ttcggctcat gtaactagta tcgctgcgag
   116521 acagggtgta gaagtggtgc gcgtgcatga cgtagctagt cacaggatgg cagttgaaat
   116581 tgcctctgcc attcgtctgg ctgatgaagc ggaaaattta gatttaaaac aatataaata
   116641 agatgaaaga aattgaaaac aatcagtgga ttgctaacta ccggacggat caaccgcatt
   116701 ttggattgga acgaatggtg gaactgttag ctttgcgtgg caatccccat ctcaaactca
   116761 aggtcctcca tatcggaggg actaacggca agggctcgac tattgctttt ttgaaaaaga
   116821 tgctagaaaa gctagggctg agagttggcg tgtttagctc gccctatctc attcattaca
   116881 cagaccagat tagcatcaat ggggaatcga tctcagaagc gaggctagaa gctctcatgg
   116941 cagactatca gtctttgctg gagggagaag cggtcgccaa tttacagggc acaaccgagt
   117001 ttgagattat cacagccctg gcctatgact actttgcctc agagcaagta gatgtggcca
   117061 tcatggaagt tggcatgggt ggacttttgg atagtaccaa tgtctgtcag cccattttga
   117121 caggaattac aactattggc ttggatcatg tggccctact tggtgacacc ttggaggcca
   117181 tagcagagca gaaggcaggt attatcaaac aagggatgcc cttggtaaca gggcgtattg
   117241 ctccagaagc cttgactgtg attgaccgca ttgcggaagg gaaagatgcg ccgagacttg
   117301 cctacgggac agattatcag gttcgtcatc aagaaagtgt ggtgacaggg gaagtctttg
   117361 actatacaag tgctgtcaga caaggtcgct tccagactag cctgcttggt ttgtaccaaa
   117421 tagagaatgc tgggatggcc atagctttac ttgatacttt ttgtcaagaa gatggtcgag
   117481 agctagcaag caatgacttt cttggtcaag ccttggaaga aacaagttgg ccagggcgtt
   117541 tggaaatcgt gtcaagagat cccttgatga ttttggatgg agcccataat ccccatgcta
   117601 tcaaggcctt gttggtaacc ttgcaagaac gttttgcgga ttatcataag gaaatcctct
   117661 tcacttgtat caaaaccaaa gccttggagg atatgttgga cttgctggga gccatgccag
   117721 ataccgagct tactctaaca cattttgcgg atagtcgggc gacggatgaa agcgtgctga
   117781 aagaggcagc taagtctaga aatctcagct accaagattg gcatgatttt ctagagcaga
   117841 atgtgacaga taaaaaagaa gagaaacaaa cagttaggat tgtcacaggt tccttgtatt
   117901 tcttgagcca agtgagggcc tatctgatgg agaggaagaa cgagaatgga tacacaaaag
   117961 attgaagcag ctgtaaaaat gattatcgag gctgtaggag agaacgctaa tcgcgagggc
   118021 ttgcaggaaa cacctgctcg tgtagcccgt atgtatcaag agattttttc aggtcttggt
   118081 caaacagcag aggaacattt gtcaaaatcc tttgaaatta ttgacgataa tatggtggta
   118141 gaaaaggata tctttttcca taccatgtgt gaacaccact tcttgccatt ttatggtaga
   118201 gcgcacattg cctacattcc agatggtcgt gtggcaggct tgtctaagct agcccgtacg
   118261 gttgaagttt attcgaaaaa accacaaatt caagaacgtt tgaatatcga agtggccgat
   118321 gccttgatgg actatctagg tgctaaagga gcctttgttg tcattgaggc ggaacatatg
   118381 tgtatgagta tgcgtggtgt tagaaaacca ggcactgcaa ccttgacgac agtagctcgt
   118441 ggtctatttg aaacagataa ggacctccgc gaccaagctt atcgtttaat ggggctataa
   118501 aaagaatccg cttcaagcgg atttttctag aaaggaatca ttatggatca actgcagatt
   118561 aaggatttgg aaatgtttgc ctatcatggt ctttttccta gtgagaaaga attggggcag
   118621 aaatttgtcg tttcagccat cctatcctat gatatgacca aggcagctac agacttggat
   118681 ttaacagcct ctgtccatta cggagaattg tgtcagcagt ggacgacttg gtttcaggaa
   118741 acgagtgaag atttgattga aacggtagcc tataaactgg tggaacgtac ctttgagtct
   118801 tatcctcttg tccaagaaat gaagttggaa ctgaaaaaac cttgggcacc ggtgcatttg
   118861 tcactagata cttgctcggt aaccatccat cgccgcaagc aacgagcctt tatcgcccta
   118921 ggaagcaata tgggagataa acaagcaaac ttgaaacaag ccattgagaa aatgcgaaat
   118981 cgaggtatcc atattctcaa agagtccagt gtcttagcga cggagccttg gggtggagtg
   119041 gagcaggata gctttgccaa tcaagtggtt gaggtggaaa cctggctacc agcacaagac
   119101 ttgttagaaa ccttgttagc cattgagtca gagctgggac gggtgagaga agtgcattgg
   119161 ggccctcgtt tgattgattt ggacttgctc tttgtggagg accagatcct ttatacagac
   119221 gacctcatat tgcctcatcc ttacatagcg gaacgccttt ttgtccttga gtccttacag
   119281 gaaattgcgc ctcattttat ccatccgata ttaaaacaac cgatccgcaa cttgtatgat
   119341 gctttgaaaa aatagaaaaa ctctagtttt cagtcacttg caactgaagg ctagagtttt
   119401 tatactcttc gaaaatcaaa ttcaaaccac gtcagcgtcg ccttaccgta ctcaagtaca
   119461 gcttgcggtt agcttcctag tttgctcttt gattttcatt gagtattaaa ataggtcatt
   119521 ttcttctggg aggaggatag tttctctacc gtccatgtct aaaaccagta ctcttggggg
   119581 ataacgaggg tcgaaaggat ggttaaagtc aaaatcaatg gctgtaggga ggtgttgact
   119641 tgaaaagtgg aaggtaatct ttccttggtt attaagcaat tgaaactcga gttcttcttc
   119701 caattcaaag acatttttta agaaatgatc gatgatatac caaaaagagt caatgatgtc
   119761 atcgggcaag ctggtaacaa tgccaaaact agcagaccgc atgtgggtat tggtaaaagc
   119821 catatctctg tcccctttct tttcccttat catacagcaa ataggattaa aaatcaagaa
   119881 aaggtgattt tttgaaaagg attttaacta cagggaaaaa gaaggaaaaa aattcccaaa
   119941 aatctaccga agttaatagg taaattccca aattaacttg attatataac tttcagttac
   120001 tttgagaagt taccgaaaaa tatttttcat atctattgac ttttaggggt gaaatttggt
   120061 atgatagtag gcggtattgt ttaccccatt tgaaaggccc cggaaccttc caaatacttt
   120121 tcgatgggaa ggaacaccca tcaccgtaaa caaaaatcga actatatata ggagaaatca
   120181 tgaacaaaac aacatttatg gctaaaccag gccaagttga acgtaaatgg tacgtagttg
   120241 acgcaactga tgtaccactt ggacgtcttt ctgcagtagt tgctagcgta cttcgcggaa
   120301 aaaacaaacc aacatttaca ccacacactg atacaggtga cttcgtgatt gttatcaatg
   120361 ctgaaaaagt taaattgact ggtaaaaaag caactgataa aatctactac actcactcaa
   120421 accacccagg tggattgaaa caaatctctg caggtgaact tcgttctaaa aatgcagtac
   120481 gtttgattga gaaatcagtt aaaggtatgc ttccacacaa tacacttgga cgcgctcaag
   120541 gtatgaagtt gaaagtattt gttggagctg agcacactca cgctgcacaa caaccagaag
   120601 ttcttgacat ttcagaactt atctaaggaa aggaacaata aagtatgtca caagcacaat
   120661 atgcaggtac tggacgtcgt aaaaacgctg ttgcacgcgt tcgccttgtt ccaggaactg
   120721 gtaaaatcac tgttaacaaa aaagatgttg aagagtacat cccacacgct gaccttcgtc
   120781 ttgtcatcaa ccaaccattc gcagttactt caactgtagg ttcatacgac gttttcgtta
   120841 acgttgtagg tggtggatac gctggtcaat caggagctat ccgtcacggt atcgctcgtg
   120901 cccttcttca agtagaccca gacttccgcg attcattgaa acgcgcagga cttcttacac
   120961 gtgactcacg taaagttgaa cgtaagaaac caggtcttaa gaaagctcgt aaagctagcc
   121021 agttctcaaa acgttaatca atacgattat atcaatgttt caaagcactc aaaggtttgc
   121081 cctatgggtg cttttttcta tactttctaa aaaagtttgc cctaaaattt gccctaaaat
   121141 taccctactt gtttttaaga tgttggtagg caacttgtcc agcagataat ggaactatgt
   121201 ttgaagcatt aacataagtt ttagttgtaa ttgtatcact atgagttaat gcttcagaaa
   121261 tggcttctaa gctcattcct gcctttttag caagtgtcgc tcctgtatgt cgtaatttat
   121321 gaggtgtggc gtgttttaac tttgggtgcc gtctttttac ggagttcatt ttgttattaa
   121381 gataatcaac gtgtagaggg ctatttacat tacctttcgt atctatatag gtaaagacta
   121441 gttgatcgga tgtttgcatt ataccaaatt tcgctaactc atatttctgt tgttttttcc
   121501 attctgaaag aagtgataca aggtaactag gaattgaaaa aatcgttttc ttatttcctt
   121561 ttgttgactt cacattttta tatttgtcaa gtgcatgcct taagtcaatt tgagcatttg
   121621 ccaagtctat atttttccaa tgtagagcat aggattctga ttttctatcg ctcaaaataa
   121681 aggttgtaaa gaataggaca taatctttta gtgataattt atcgttctct aaatcttctc
   121741 taaaagcatc aaaccaatct tgtaattctt cactagatag atacaggtct tcctcatttt
   121801 tggagtcttg gagttttagc tttttggtag ctttaattcg cttaattgtc ttggataatc
   121861 gatttgattc tatgtactct aattcctcag cccaatcgaa aattgagttt acatagcttc
   121921 gaataacctt gaaattagca tactcttcag ctttagcagt cattaagttt agtacgactt
   121981 gcttattctg attcagaaaa ttgattgaat aattaccgaa cattggtaag atatgctttc
   122041 tgaaaacagt tttagtatta tcaatagtaa cttgtgttgg gggtttagtt gttgaagttg
   122101 tttgaccagc tttgtatgaa tcccaccaaa tattattaaa gaactcagag aatagaatat
   122161 cgttagtttt agaaagtagg atatcctcac cattttcaag ttgatgtatc ttagttaaaa
   122221 tttctagttc agcttctttg gcctcctttc ttgttttata gcgtttaaca aagtgatttc
   122281 ctttaatccc cattttaggt cggatttctt taggtatata cactttaaga ttgtaagtgt
   122341 tactatttgt ttttgtaact gtcatgatgt tctcctttta cgagtcagga tatatcatta
   122401 gagatattat agcatagctt ttctacaaag ccatttatca atctcatttt tattgaaacg
   122461 gacagtctta ccaattttaa taacgggtag ccccttttgt atccagccat ctaatgtatt
   122521 gttagatatc cctagatatt tgcaagtttg ccccttgtta aggtaaggac tatctaaacc
   122581 taaatcttct ttgaaatgag aaatttcatt ttgcaagaga ttagtaatca tcgactgtat
   122641 ttcttgaact tgttctgttg gtagaataac ttgcattttt tccttactcc ttacttaact
   122701 ttattttttt gtattttact ttattgtcaa ttaagtgtcc ttttcgaaat actttgctaa
   122761 tatagttgct ttcatatagg atatcttcat tcttaacaag gttatctaag gattcacttg
   122821 taaataattt tatttcttca ggcttttgta aattacgaga agaataaaaa gccttctttc
   122881 ctagactctc taataattcc tgtcctatgc ctttttccat atattttgca acataacgac
   122941 cagcattaga agaatcatct aacttattta gtttgtttat ccgaactgca cctaaccccc
   123001 aaattgtcag taattcttta tgagggataa aaggaaatga aaaaaggaga atgtgtgcat
   123061 gccacgctcc ccttttttgt cgttctaata ctgcaatata tttaataagt ctttttttgg
   123121 aatggtatat gtgatagttt aaacgtttaa taaatttatc aaaaagtaaa ttaaactcat
   123181 atctgttttg tatattttct ttggttgtaa gggtaaggaa actagttctg tcatcaaaat
   123241 ttgtatctat taggcgttga agtttccatt tagaattttt acgagtgtta gaaattcttt
   123301 ttattcgttc atcttgttca gcagttgtga gttcttcaaa agttctacgt ttcttctttt
   123361 cttttagtga aatatgttct tcatcaattt gagtagtatc atttgaaaaa attggagatt
   123421 cgtattccca tatttcaagg tacgaagaag ttcggataat tttgcgattg taactcacaa
   123481 aatcatctcc ttttctcgta atgtttgctt atataataaa taaactagga gaagcaaagc
   123541 tcctccatac ttctatcatg tgtttctaag catcgctctg ctaaacacgc ttccagcttg
   123601 ccgacttcca gtcggcagtt tcgcttagta gcatgatgag aagtagtagt taaatttgag
   123661 gtttaggtaa ttgttttaat gtttggtctg tagcccagtc agttgaaatg atttcaagat
   123721 gtccttggtc ataaactagc aaatctccgt taccaataaa ttgatattta ttatctttgt
   123781 caatatataa tgaaaaagta tctataccaa taatattttt agaaatatca atagattctt
   123841 ttggagtatg tccaacaatt tgtttaggaa agtcttggtt gggaagcagt tctaattctc
   123901 taaaatgtgc ccataaagga gaacccccaa gagcttcccc accacgcatt ggtcctattg
   123961 tataagctag aatatctaat tcttcttcat gctctttggt ataggggaaa aaatgccatt
   124021 tttgaggatc aaatatttga ttgaaaccag cgtgactgac taaataatca tctagttgat
   124081 aagccacttg taattttaaa tcctgcaaca atccttgaac tgcgaaaaac acttctaaat
   124141 tttgaattga gaaaggagct tgatctccca gtaaataata agcatcatga ttacctataa
   124201 gattaattac ctctattccg ttttgctctt tatctatttt ccaagagtat aaaaaagtga
   124261 gatctttggc atatagttgg atattgttag tttgtccatg taagtcaaca taatcaccaa
   124321 gaaaaatcac tcttttaata ttatgtgttt ggataatctt gtcaataatg ggtaaaatta
   124381 gttgagattt taaatgtaag tcgccaatta ataatgtctt catatagatt cccctcttta
   124441 tttttgatat tagtctaaga atagagttaa attctgccaa tttttttagg atgttattta
   124501 atattgatag gattttgtaa ctgtatcata gcagataaca ggtattgttt tactatgata
   124561 cacatcgccg tcaatgaagt aatggttttt accatcaaag taaatcttac cttgataagt
   124621 tttatcttta gctacttccc aagaagcaat atggcccgaa ataatagctt tatgaaatct
   124681 accagtggta attggaaatt tgtttgtaaa tatctttgaa ctcgttagtt ctttccaaag
   124741 cattcctgct tcttcatcaa tgcctgcatg aacaaaaatt tgggtatcag tttcataata
   124801 gcgtttatcc ttatatcgct ttttaaacca gtttataaat gggttgaatt tgatattatt
   124861 tttaatttca tttctaacac ctgtttcaaa gttgttagca ttcgatttaa aaatatagtt
   124921 caattcctct ggagagaaga agctttttat tgtttctgga aatgctgaag cagtaggttt
   124981 atctaaaatc aaccaatcat aaaaccattc ttcatggttc cctagaagag taataatttg
   125041 attaggataa atctcctcaa gtttgattat tttggaaatg acttgaaaag attgaagtcc
   125101 attatcaata tagtctccga ttagaataag acgattgttt ttatcagata ggtctacttt
   125161 actgagagca cttatgaact catctaggtg accgtgtata tcagatattg caaaaagttt
   125221 agccataaat agtatcaccg aattatttag aaatagggac tacatcgtta caagaaaacc
   125281 ataaatttcc gttaaattgt ccaactgtta aattagataa tttaacgggg catgtttttt
   125341 tatctgataa taattgagga gtagccgtag gagataacgt attaactttt atctggatca
   125401 tttccataaa gaaatcagaa tcctcatctt gaattgaaac attaagacgt agtgctacag
   125461 gtttatttgt ttctctgtcc aaaacttctg tatatccttt tactgccacg aatttattgc
   125521 ctaataattc tggtttaaga aaatcgttaa ttttcatata atacctcgtt tctttttgtc
   125581 atcgcttaag cgatgaggaa tagatatttt tgctgaaaat ctattgaatt taagcaaaaa
   125641 tatctattga aattattttg actttgttac gtataattgt agttctttta taaaatcgaa
   125701 ttgtgttgta tcaagatagg ggctttccca atattgagct ttttcttttc ctgagccctg
   125761 catataaaga tatcctgctc ctttttcttc aatagattta aacttatcag gtgtagccgt
   125821 gccaaatacc atgcggtatc cctctattga gtttgctcct aaagctattc ttagtcctaa
   125881 attatctcta agatcagtgt tgagagtttc agctctcatt tgttgagcag atataaggat
   125941 aaatactcct gcttgtcgcc ctagtagaat aatttgttta ataccgtcca ttgcttcagt
   126001 gataacttct ttagattttt tatctgttgc cgaagcttga aatgctccca tttcatcaaa
   126061 tataagccat actggtttaa atccatgatc ggcaaaattt gaaccgtaat gaaagttatc
   126121 acgcatggct tgatatcgtt cctgcatttg ttcaactacc aaacgtacaa tacgagcaat
   126181 attattggga gttgtagcta tatatttatc acttaaataa tgagatagac tacctaaatc
   126241 actgttctta ggatctgcaa tatatagtgt tgaatttctt ttaagaagtt caataattaa
   126301 gaaagatata aatatagatt ttccactacc tgtaccacct gaaactaaaa tatgaggaca
   126361 ttttatagga ttataagtta tatcatatcc taagtctata tcaagactat ctatctcttt
   126421 tttatgatta tggggtgata atattagtct atcaggtttc ttgtaataaa agtgatattc
   126481 aacaatatta ggatgagtaa ttttttcttc tagttcaagt tctagaactc cagctaatac
   126541 atcatcaagt gtctgaacct ttttactaaa ttcgtcacct ctgataagcg ctttaatgat
   126601 aatacgactg ttttgattat ctaattcata ttttaaaatc gcacttctaa taatttcttc
   126661 gtaacctgaa ttatcctttt ccgaagtgta gagatgattt gtatataaaa caagtagtaa
   126721 gctttccctg ataattaaat caaaatctag ttcgtatcta aaatctttta atttattatt
   126781 tattttatag attgctagaa taccaaagac aatacataag atttgaataa aagcaggagc
   126841 tctaatactt actattaaac ctaataaaac aaggatagaa aaggtaatta ttatcagatg
   126901 taacaatttt aaacgtgaac ttgtaataaa ataatttctt tttaagttag cttctttttt
   126961 taatttaaac ataaaaagtc ctcttatgta gtataacaca tatacatttg tttttataag
   127021 ggacctaagc aggttttgct taggttattg ttgtgtcttc caataggaat aaacaacaag
   127081 tttaatgatg taactaagcc ttggtaatct agtagcacca tcttctttca ttaaatgata
   127141 tcgaaattca tcaagaccat ttagaacatt ttcatctaaa tagagtctag gggttaccga
   127201 tgtttctaga ctaggattga cagttttgat atctttttcc attttttgac gcaaattctg
   127261 ccatttagca atggagtaat attttgtatt tctatatgct tcttcaataa tacttccgat
   127321 agaagctttt aaaacgatat taaaagaaac accatttaat tcatcgtaat gatttgatag
   127381 aagtgtttgt tctagggtat ttagaaaatt atcctgattt agttctttga ttttacgctc
   127441 ttttttttga ataagctcat ctatccatac tttggcttcg tatgcaagac gaacactttt
   127501 atatactctg accacaaatc ctccttttta aaattcatta gaaaatctta ttgtctccat
   127561 atttttaatt tccttataga aattgaaatc tttttgatct aacttatcac agatttgttt
   127621 aatgataaat ttaccacgtt cttcaattcg ctcattgact tttttgagga aaattgagaa
   127681 ttcctccgta ccttctagct ctttgtttct aaaggaatga ttttcccaaa aaatttcagg
   127741 ctgataatta ctatttacat atggttgtaa gtaatagttt ttaataaatt ttttccaaga
   127801 ttcatcttca gttaagaaag cattaaacca ttcatataaa gaaagtaaag taagatccca
   127861 gtaatctttt gaaaaattat atcgaccagt attcatccaa tgaggtaata caataaagtt
   127921 cccaattgtg tgagttagtt cagcaaattt tttaaaatta tctgcatttt tagcgataat
   127981 atcaaatttt tcataatttt tatttttata tagatttatg taatattgag ggaaatcttt
   128041 ctttcctatt gttttgattt cgtctaattt taattcgtta tacaaaaaat tatagttata
   128101 actaagttcc atagctttct tgaacgtcgt taaataagaa tttatagttt ctcctctaat
   128161 gatactatct tgtgactctt gccatcccaa aagtttatat agtatagaat gcttccttat
   128221 cactgtcagc atactttcca attagtttag taactcgaaa agtagttgga tttgtaagtt
   128281 cagcgttttt atattttaaa aaatttgtaa tactatctgg tgttagcgta tcagaataac
   128341 aatttttaaa atcccattcc catggtttga tattattttc atcacaatat ttcaaccaat
   128401 caataacttc ttgatgttcc ataagctttt cctttcggtc ttattaaagt taagttttga
   128461 taatcttaag caactgtttg aagagtattt ttattttatg atgatctagt gcttacagcg
   128521 taaatgtagg ctaaatagtt tgcaaaatct ccttgccgtt gtcggtcatc cgtaattttg
   128581 tcaaaccagc tagtatttcc tcctgtagat tcgatttcgt tttttagtgc attcaattgt
   128641 accatgaaag catcatgagc agaggttcta agagtcccat gcttgtcttg tctttctttt
   128701 gacactgttg cagatttgac acgaatttca gtatactctg aagctaactc aatcaacatt
   128761 gtccagtcat cgaggaaaat tggatctttt atgtcaaatg aactaattag ttcattatag
   128821 attttatgtg catcttcaaa agtcaaagca gttttttctt gaagaaaatc agaataagtg
   128881 taaatttcca taaagggcct ccgtaaataa ttatttttgt ataaccacaa ctatattttg
   128941 attataatcc tatataaaaa taaaatcaag gatttttaat attccaactt agccatagtt
   129001 tttatttttt tgcacctttt aatcagttaa aacaattcat aaagctatat aatatagcat
   129061 acaagatacc gagtaagcgt aattttgtag tagaaggaaa caatcctaat agtcatctaa
   129121 tccgtcaaaa atctctcctt gttcatcttc gtcataatag tcttctaatt cctcatagaa
   129181 gagatccaaa gtttcttggt cgaacatatt cataactcct ttatattttg taatctaaat
   129241 atattatata taatccgaaa gtaaatgtca actattttat aaaaaaataa tccaaaatca
   129301 tattgaaata aaataataaa ggaggagaag tctcctctat tgtatcaatg agatgttatt
   129361 tttaaaattg tccattatgt tttctagtac attataattt atgggagcaa ctatatcttg
   129421 caagttttgt tttaattcct caattgcttc catggtagac aaatttttat ttgtatttat
   129481 ctttccagtt ttatttaata taatagctcc ttttaacata aatttaacag caacgccgat
   129541 ggttacactt ctcgtagttg taaaatttgg taatagtatt tttaattctc taattccctt
   129601 ctcaacctca tcacttattt gtactttaac atttgttccg taaccttttt gatattctaa
   129661 atattctagt gatattgttt ctgtatcatt aatgatagat gtccaatttg taataatttt
   129721 agtttcttcg aaagctctag tgagtatttg actacgcgtg agttcaaatt tagaattatt
   129781 tgaatacatt tttttcaatt tttcaaaata aaaaatagct tcacttgata ctctaacttg
   129841 aaattccact tctgaattct cctttatagt aattgtatag tttattataa ttaaaaatgg
   129901 atttatttta ggaaaaagta caaaagataa tgaatattat cgataaacaa atcagtttct
   129961 atagtggatt agttctagaa tagtacactg tgacttctaa aatattgcta gaaattgatt
   130021 tgacttttcc agattttatt ttattctact gtaagtacct aaaaaagtta aatgtttatc
   130081 aaagacctca agtaatatgg ttaacttttg cttttctcta tgtgtattgt ataggtaaac
   130141 gattattgtt agaatctgtt attgtaaaat gttttattaa atgtaacgtt tgatcgagtt
   130201 gaatatttcc agcaacaatc atgtcatttt ctttttttat aatgccaaaa caagctatcc
   130261 attctccttg tgtagaaatt ggaatcatat cactgttaaa atagagcgag tatgtcttaa
   130321 tgctttgttt tgagcgagga tcaggtataa ctaaaacatc gtggctaaaa atataatcaa
   130381 aaccatttcc tgaatcaata taagtatcta tgactgggaa gataaaatcg gaatttgaat
   130441 aatctaaagt tatatttttc gcgattacct tctctttgtg aatttggtag accaaaacat
   130501 taggggagtt agaaaataat attgatgtca taagttctcc tttttaattc tagaatatca
   130561 ttcagcttat ttacttaatt gtaataagaa attagcctag tctgttgtaa taatcacacc
   130621 gaattcatga tcagtaatag ttttggtagc aaaataatca atcccatctt gattgatatc
   130681 aaaattagcc aatacataat ctcctggaat attacatcct tcatgagacc aaattttatg
   130741 gattttatgg ataggatttt ctaataaatt atctagtgct ttattattct tgaagttcac
   130801 ggtattaaaa tctccaatga gcaacaactt gttgttcttg aatttttgta caaaattatt
   130861 gatttccttc cagaaactca caacatcgcg acttggtgga acatgtgtac cgtaaattac
   130921 taaatcattt acttgtattg catatgctct ggcattacga tcatggcctg tcgaaatatc
   130981 ttcgtctcct agaccatttt taacaaagaa aactgtcata gatggacgtt tttttgattt
   131041 tactggtact gattttggaa tatacccttt ctccaccatc agaggttcaa aaatttctcg
   131101 acactcttta gaatttatat cgtattcttg tatgataata atatcaggtt tgtattcatc
   131161 aattttactg ataaaagaat ttattgtttc ctttttatcc agcttgtccc attcttgaat
   131221 atatttgcca tttccaaatt tgtttttaaa atcttcacga tggttttcgg ggccaccaaa
   131281 gtcattaata ttaatattta gtattttcat attctgattt cctttttaat tttagctttt
   131341 tcaatagttg aatgtgttaa ggaggcataa taaacacgaa cttcttaagt aaataatgat
   131401 ttgttaggta atgatacaaa tgtaatctaa aaacacatta tgtaattcaa ttttaccaag
   131461 aaactagata tttgtcaacc ttaattattg gggaaaataa aaggaatatt ttaatctttc
   131521 tattccaaca atgtagtaga aggtggttag cattttggtg tttaatttac tacttatata
   131581 aaacgtacca tctttacttt tttgaaagta gagatggtac gcttggttta ttgatttagt
   131641 cattgatttt ttgtgctata ggccaaattg ttgatatacc tgactcatat ttgtttattt
   131701 tgtagaagaa tttgccctat ttagataaaa ttatttaaaa ttagttgaaa atttctgaga
   131761 ttttagtagt taaaaatagc ttaattaaac gtgttcgaaa gagcttagtt gttaggttag
   131821 ccaaaccagg tcttaagaaa gctcgtaaag catcacaatt tagtaaacgt taattcgaaa
   131881 gaattactat acttatacag agcacctttc ggggtgttct ttttttatac tttcttacta
   131941 aattggtgca attgacacag ttgttgcgac tttagtcgct tacaaatgtg gctgcaacct
   132001 gacaaggtca gttgcctcaa aacgttaatc aatacgatta tatcaatgtt tcaaagcact
   132061 caaaagttta ccttattttt atagtaaggt gaaataagaa taggacaaac cgaggataat
   132121 caaatcgaat tctaacaatg ttttagaagt agaggtgtac tattctagtt tcaatctact
   132181 atattatgga taatgcaaga ttccatagaa tgggtaagtt agaactttta tgcgaggagt
   132241 ttgggcataa acttttacct cttcctccct actcacctga gtacaatcct attgagaaaa
   132301 catgggctca tatcaaaaag cacctcaaaa aggtattacc aagttgccat accttttatg
   132361 aggctctttt gtcttgttct tgtttcaatt gactataaat cgctataaga aaaaatcatt
   132421 ttattggtat aaagaagtga ttgaaagtaa tggcgaaacg ttagataatt agttcataaa
   132481 aaacaagttt gatcctcatc taaacttgtt tttttaaaat tgaaggatga ttttgtagga
   132541 tataagatga cattgactat tcatgtatat tataaaggtg atggagatag tgcaataaag
   132601 tttgcaagag aaatgcttga tagtggcctt gttgaagaaa ttagaaatca aaaaggtaac
   132661 ttgaaatacg aatatttttt accaattgaa aaagagggaa ctattctcct tattgatcag
   132721 tggataaatc aagaaacttt agataaacat tatcaatcaa agacaatgca gaaaatctta
   132781 gatttaagaa aaaaatatca cttgcagatg caagttgaac gttatataga agatgattct
   132841 gggatgccag aaagcgataa gtcgtttata gacacaggga attagaatta ttgtgagagt
   132901 ttttgtagtt tgaaagtatt gaaaatcgta aagatatcat tacgagaata caagaagata
   132961 ttgttctatt tccattaaaa attacttctt tccttaacaa taaggaaaaa gaatgcgttt
   133021 tcatcttttg gtttgaggtt tataataaga gtatcaaagt caggaggaaa aaagatgact
   133081 acttttaaag atggattttt atggggtggt gctgttgctg ctcatcaact tgaaggtgga
   133141 tggcaagaag gtggcaaggg aattagtgtt gctgatgtta tgactgctgg tcgtcatgga
   133201 gtagctcgtg aaattacttt gggagtttta gagggtaaat attatccaaa tcatgaggcg
   133261 atagattttt atcatcgtta taaagaagac atagcacttt ttgctgaaat gggattcaag
   133321 tgcttccgta cctctattgc atggacacgt atctttccaa aaggtgatga gttagagccg
   133381 aatgaagaag gattacagtt ttatgataat ctttttgatg aatgcttaaa gaatggtatt
   133441 gaacctgtca tcactctatc tcattttgaa atgccttatc acttagtgac cgaatatggt
   133501 ggttggaaaa ataggaaatt gattgatttc tttgctcgtt ttgcagaagt cgtatttaaa
   133561 cgttacaaag ataaggttaa atattggatg actttcaatg aaatcaataa tcaagcgaat
   133621 tatcaggaag attttgcacc atttactaac tcaggtattg tatatgagga aggtgataat
   133681 agagaagcaa ttatgtatca agcagcacat tacgaattag ttgcttctgc acgagctgta
   133741 aaaattggtc atgagattaa tccagatttt caaataggtt gtatgattgc gatgtgtcca
   133801 atttatccag ttacttgcaa tcctaaggat atcttaatgg caatgaaagc tatgcagaag
   133861 cgttattatt ttgctgatgt gcatgtttta ggtaaatatc ctgagcatat tttcaagtat
   133921 tgggaacgaa aaggtatttc agttgatttt actgaccagg ataaagaaga tttacttggt
   133981 gggactgtag attacattgg tttcagttac tatatgtcct ttgctataga ctctcatcgt
   134041 gaaaataatc cttattttga ttatcttgaa acagaagatt tagtgaaaaa taattatgtt
   134101 aaggcttctg aatgggagtg gcaaattgat ccagaaggtt tacgttatgc gttaaattgg
   134161 tttacagacc actatcactt accactcttt attgttgaaa atggttttgg agctatagat
   134221 caagttgcag cagatggtat ggtacatgat gattatagaa ttgaatatct aggtgcccat
   134281 attcgtgaaa tgaaaaaggc tgtagttgaa gatggtgttg atttaatggg ttatactcca
   134341 tggggatgta ttgatttggt ttcagctggt accggtgaaa tgcggaaacg ttatggtttt
   134401 atttatgtag ataaagatga caatgggaag ggaagttata atcgttcccc gaaaaaatct
   134461 tttggctggt ataaggaagt tatttcatct aacggtgaat cagtagaata gtataaacaa
   134521 actgagatta ttctcagttt gtttagcata ttgggatgac atatgattgg aagtattgca
   134581 gcaattttaa caacatttgc atttttacca caagtttttc gtatagttaa gacaaaggac
   134641 acaggatcta ttgctctagg tatgtatgtt atgcaagtta ttggtattgc attgtggctt
   134701 gctcatggta ttcgtatagg agacttgcct ttgattttag caaatagtgt ttcatttcta
   134761 ctctcaggaa taattttatt ttataaattg aagtataaat aatttttttc catatcattt
   134821 aggaaaatga gggaattatc attggaaacg ctttatttta taataaaaat agataacaaa
   134881 taagccaact tagcacagct ttgattggat ttaagaaaag gagaaaatat tatggcaaaa
   134941 gctttaatta tttgtgcagc aggaatgtct tcatcactta tggcacagaa aacaacagag
   135001 tttctaaaag gaaaagggaa agatattgta gttgatgcta ttagtgctac tgaaggaggg
   135061 aaagctatcg cagcagcttt tgatttgtat cttgtcagcc ctcaaacaaa aatgtacttt
   135121 aagcaatttg aagaggctgg ttctaaagca ggaaaaccag ttgtacaaat acctcctcaa
   135181 gcatatattc ctattccaat gggaattgaa aaaatggcta atttgattct tgagaatatt
   135241 tgatgaacac atgaaatgtc aataaatatt taggttaaga taaattgttt tgagtttgat
   135301 ataaactgat ttaagtgtat aatatgcttc aatatatgaa aacatacgtt ttaggaggga
   135361 atgaatgtgt taaacattaa agagaaagat atccttcaat ttttaataaa aaataaggaa
   135421 cgttttgtta caagcaaaga actggcagaa tatttatcct gttcagatag aactgtccgt
   135481 aatgtactga aattaattga gaagacaatg attattcaag gagtccggtt gatttcaaaa
   135541 caaggtcaag ggtatcaaat attttttgag aatcaaggcg cttaccagga gtttagacaa
   135601 acttatgaac tggaagaaga ctatacgaaa actgcggttt caaaaggtga tgatcgttta
   135661 gtatttatct taaataaatt attatttgag caagttccag ttctttttga tgatttagct
   135721 gatgaacttt acgttagccg ttcaacatta tctcatgatt tcagaaagat acgagtgatg
   135781 ttatcagagt ataatttgtc cattgagagt agggcgaata aaggagttta tgtctcaggc
   135841 gaggaacgtg ataaacgacg ttttatcata aattatttcc tagagaatca attttttaaa
   135901 acaatacatt gctatgtaaa atttaacttt tttgatcaaa ctgttccatt agaagaattt
   135961 gctagaattg ttttggatga atgccaagag gccaacctaa aactatctga ttttgtacta
   136021 cagaatttag tagttcacat agcattgtct gtgattcgtt taaaatccgg atttgaaata
   136081 aaaaatatag actgtcagat gactgatgat gcaatagaga gaaaggttgc ccaaagaatt
   136141 ctttctaaag taagagaagt aacaaatcag gaatttccag ttcaggaaat agactacatt
   136201 actttgcatt tgttagctaa gagtcaacaa tgtcaaaaaa atcagaagaa tatttctgaa
   136261 gaagttttaa aaaaatcttt acttaaaaca tttcagaatt taggattaga tgatatgtat
   136321 aacttttctt cagatttcca actaattgaa ggattgataa ctcatctaat gacactacaa
   136381 gtacgtttag aaagccggat taccttaaat aaccctttgg tagatgaaat taaacagaat
   136441 tatagtgata tattctttat gactagagaa attcttgcaa atatggacaa gttcttggag
   136501 tggacaatat cagatgatga agtagcatat gtaagtcttc actttttagc tgctatggaa
   136561 cgtagcaaag agagtactaa gtttaatatt cttgctattt gtgcaacagg atttggtgca
   136621 gcccaaatgt taagaaatcg tttggaaacg gagtttggga agcgagtaga agttgttgat
   136681 gtaataggct attatgaatt gaatcaagaa aaacttaaag gaatagattt tatagtgtca
   136741 gctgttgatt tatcaaatct atattttcaa atcccagttt ttaaagttag tgtgtttctt
   136801 aagagtgatg agatggaaat gattagaaaa gctatggatc agatgcaagt ttctagttat
   136861 gtacaatcat caaagattaa caaatttgaa aacaacggct ttagacagta ttttagtaaa
   136921 gaaaactttt taatatgtac tgaatcagac aaggtaaatt tacttgaaaa gatggttgag
   136981 agtttatctg ttggtgaatc aaatgagttt gaacaatctt tactttatgg aattaaacag
   137041 cgcgaagaat taagttcagt tgttttttct gaaaaaattg cagttccgca tcctattcag
   137101 tcctttggta cagagggaaa ggtttcggtt gcaatttgta aagattcgtt actctgggat
   137161 aatcaaagtt cacatgtcca gctagtattt cttctatctc catcaatata tgggaacgaa
   137221 ggtttggcaa ctgtgactaa aaagatagtc tctctgacag agaatgatga attgcaaaat
   137281 cagctaatat cttgcaataa ctttgaagat tttattaaca tatttgagaa gataaaatag
   137341 gaggttcata tgaatcaaga ggaactgcag gttgcagcat ttgaaattat cctgcattcg
   137401 ggaaatgcaa ggtcagaaat acatgaagca tttgcaaaaa tgagagaagg tagttttgat
   137461 gatgcagaaa gtaaattaaa tcaatcaaat gagataattc ttgaagcgca tcatgcacaa
   137521 accaaactct tgcaagaata cgcaagtgga gtggaaatta aaattgaaat tatcatggta
   137581 catgctcaag atcatttaat gaccactatg acattattag aagtagcaaa ggaaatgtta
   137641 gctctttata agaaagttaa ctaaatatgt gttgttatat aaggaggaaa tgatatggat
   137701 aaaaaagaac gacaaaagat tgaacaacaa cgtcgagaga tggctctaac taatactttt
   137761 ttcaatcgat atcttcttct acgttattca atagcactct tcttttttgg gaatatttat
   137821 tggcttttga gtcagtttat tagtccctcg cctattatta ttttccccat tatgctcata
   137881 gtattttcta ttttagcaac tgttgaacaa tttaaactct atggaaatag gaaagaaaag
   137941 ttgggaataa cactaatgtt tgttagaata caaatgctta tttcaatagg attacttgtt
   138001 ttaacttgga caagttggtt taagaatctt tttccgattt ttgaaaataa ccaagtagca
   138061 cgtttatttg tttttgtagt tcttctatta ggtttagttc tgagtttgtt agacattaga
   138121 agaattaaaa aaatttataa acgaacagat aaggcttatc aacaatttgt ccaattggaa
   138181 aagaactcac ttagtttata atcctgatct agtataattt gtatttgaaa ccagtcttta
   138241 gaaagtaaaa attattatgt tttattaagg aggtctattt atggatcaac aaaacgggtt
   138301 gtttggtttt cttgaaaacc atgttatggg accaatgggc aaacttgctc agtttaaagt
   138361 agtacgtgct atcacggctg caggtatggc tgctgtacca tttactattg taggatcaat
   138421 gtttttggta ttcagtattt tgccacaagc tttctcattt tggccaattg tggcagatat
   138481 tttctctgct tcatttgata aattcacatc actttacatg gttgcaaact atgcgactat
   138541 gggttctcta tctctttatt tcgttctatc acttgcatat gaattgacaa aaatttatgc
   138601 agaggaagaa gaactcaata tgaatcctct taatggtgcc ttgcttgcct tgatggcttt
   138661 tgtcatgaca gtaccgcaaa tcatttttga tggtggaatg atgaagactg tgacaagtct
   138721 aaaagaaggt gcagtaattg cagatggatg ggcaatggga aatggagtcg cacgttttgg
   138781 gacaacaggg atttttaccg caatcattat ggcaattgtg actgttctta tttatcgtat
   138841 gtgtgttaaa cataattggg ttattaaaat gcctgaagct gttccagaag gagtttctcg
   138901 tggatttacc gctttggttc cgggatttgt tgttgcattt gttgttatct ttatcaacgg
   138961 tcttcttgta gcaatgggaa cagatatttt taaagtcatt gcaattccat ttggttttgt
   139021 atccaatctg actaattcgt ggattggttt aatgattatt tatctattga ctcaactact
   139081 ttggattgta ggtatccacg gtgcgaacat tgtttttgca tttgttagtc caattgctct
   139141 tgctaacatg gctgaaaatg ctgctggcgg gcacttcgct gttgcaggtg aattttctaa
   139201 tatgtttgta attgcaggtg gttctggtgc aactttagga ctatgtttat atattgcttt
   139261 tacctctaaa tctgaacagc ttaaagcaat aggacgagca tctgtagttc cggccttatt
   139321 taatattaat gaaccattaa tttttggatt acctattatc tataatccag ccttggctat
   139381 accatttatt ttagcaccaa tggttactgc tactatttat tacgtagcga attctctaaa
   139441 ctttattaag ccaattatcg cacaggttcc atggccaact ccagtaggga ttggagcttt
   139501 cttagggaca gcagatcttc gagctgtatt agttgctcta gtatgtgcat ttgcagcatt
   139561 cctagtctat cttccattca tccgtgtata tgatcaaaaa ttggtgaaag aagagcaagg
   139621 tatctaataa gtaaaaaagt atactcgatg atagaatcca tatagtttaa ataatgagcg
   139681 ttaacattag cagtgaagag gtctttttaa gatattcttc tctgcttttt catatttttt
   139741 cgctatgtag ggtatgaagc aaaatagaaa gtagttcgaa tagttgataa acagggaatt
   139801 gctgttattt aaaaaaaaca ataaagtaaa gtatgttatc gtagaatacg atacaatagt
   139861 aaaaaagcaa aaagaatgcg ttttatattt gggtttgagg tttataaaat aggataagca
   139921 tgctgaaaac ttagatatga caaacaaaat aaaattttta aaagctacat agaaacatgg
   139981 tataatgtat ctaaaggagg tagcatatgt ccttagatat agataaagaa aagatgacaa
   140041 tcatgggaat agcttttgaa aaccgatccg tttttaagag tgtttggtat gctttaagta
   140101 caaatatgat tgaaggatgg cgacctacgg ttagtgatgt tgaaaaatta cgagatgaag
   140161 ctcttgctct ggggatgact taatgaagcg caactgttat gagtcttatg actatgttga
   140221 tccggataat ttatataccg atccgggttc ttcagttcta agaaataagc aggaaggaaa
   140281 aaagcacgcg agcttgaata tcgtatgatt gctagtaaga gtttgaaatt atttatcaat
   140341 cctatcttag ttaatagttt aaaagtagtt tgtttcacaa ctgcataagc ttagaaaagt
   140401 tgaaaagtga taactcttta ataaactctt ggtttgttaa aagatatttt gtccactaca
   140461 ttttttcaat tgactattat ttgtcataga tataacagat agaacattgc attcagaata
   140521 atgaaaaacg catcaaaaat ggtgcgttct gtttttatgc taccataaaa ggaggaaaac
   140581 aaattgaaaa tttttaaggg agagttttat cgaatctctg tattaacaga caagctagta
   140641 aggttagaat actctcaaac tggaagtttt gaggatagaa cgacacaact tatctataat
   140701 agagattttg gccaagtttc gttagattat atcgagacat caaacgtact agatattatg
   140761 acggactatt ttcatctgca ctttaataaa ggagaattta acgccgaaaa tttatttata
   140821 gaattaaaag gaaattttgc cgtatatggt agtcgctggt attttggtga atctattgaa
   140881 acgttaaaag gaacagctcg gactctggat aaggcagatg gagcaatctc gttagaagat
   140941 ggaattatta gccgaaatgg tatagcctta ttggatgatt ctcaaggatt tatttgggat
   141001 gaacaatctg gttatattga gagagaaaat caaattgacc tgtatttctt tgcctatggg
   141061 catgattata gaggagcaat cagagacttt taccatttga ctggttcaac acccttgttg
   141121 ccaagatatg ctttaggcaa ttggtggagt agatattggc cttatacgtc ggatgaatac
   141181 ttggatttaa tagacagatt tgcaacagag aaaattccat tatctatcgg tgtgttagat
   141241 atggattggc atataactga cattccagct cgttttggaa gtggctggac aggatatagt
   141301 tggaatagaa acttaatacc aaatccagaa cagttattgc aacaacttca tgatagaaag
   141361 ttaaaactct ccttaaatgt ccatcctgct gatgggatac gggcttatga agaagcttat
   141421 cctcaaatcg caaaacggtt ggggttaaat gtagaactag aagaacctgc tatttttgat
   141481 ttttttaatc cctcttttag ggaagcctac tttaaagatg ttcattatga gctagaaaag
   141541 cagggagtag atttttggtg gattgactgg caacagggga cacaaggcat gctagatcca
   141601 ctttggcttt taaaccatta tcactatcag gatagttgta aaaatgcaga aggtggtttg
   141661 attttatcaa gatatgcagg tcctggtagt caccgctacc ctgttggttt ttcaggggat
   141721 actattatca gttggaattc cttaagattt caaccctatt ttacagcgac agcatctaat
   141781 atcggttata gttggtggag tcatgatatc ggtggacata tgttggggga ttatgacgaa
   141841 gagctacaaa ctagatggct acagtttggt gtttttagtc cgattactcg attacatagt
   141901 tctagaagtc cttttaatag taaagaacct tggttttttt cagaaacaac atctaagatt
   141961 atgaagaaat accttcgttt gagacatcag atgattcctt atctatatac catgaatgta
   142021 aagacacatg aggaaggtgc cccattaatc agtccaatct attatttcta tccagagaat
   142081 gatgagagct ataatgttcc aaaccaatac ttttttggaa cagaactgat ggtggctccc
   142141 attgtagaaa agatggattt gacattccaa tctgcaaaag tagatgtatg gttccctgaa
   142201 ggtgaatggt atgacttctt ttcagagaaa aaatacacag gtggtgtgaa gttaagtgtt
   142261 tatagggaca tctcgactac gcctgtgttt gcaaaaagtg gtgcaatcat tcccttggtt
   142321 ggttctgaga taggtatggg tgttgattta cctgaggttg tagattggta tgtattccca
   142381 gggaaacaac attcttttga aatgcttgaa gatcaaaatg gtcaaagata taaaacaaga
   142441 ttatcaatcg attgggaaat gggaatggta gagttagcat tacaaggaga ttctagtatc
   142501 gttccaagca atagaaaaca tagaattcat tttaaaggaa cgaatgtgtc tataattgaa
   142561 ttgccaaata agaatgatac agctaaattt gaatggaaag ataataaaag gacatcttta
   142621 aatgacgaag tttttagact actaaagaca gcttctcttc catatgaatt aaaagataga
   142681 ttgttaaatc aattcatcaa tgcgaaaaac tctcatgact taatgaatat cttgcatcat
   142741 caggataagg aattgagagg gcgtttgttg gaaatgatat ttactatcca aaactaattg
   142801 atataattag aaagtcattt gtttagtgta tatgaagatt ctgtatggta ttcgttatca
   142861 ctggtcacat tgaaaatgtg aaataagcac ctacaacata gactttacaa cacttcatgt
   142921 ttcatatcat ggggtgtttt tctatttaag tcaaagccaa tcaaaaaatc tcactattca
   142981 tcaggttaaa ggaaacctaa tcatagtgag attgtgaatt atagtagagt ttgtatcgcc
   143041 tcttcaattt gttttgggtc tgtttttgaa gaaaagcgtt caaagacttg cccatcacga
   143101 ctaatgagaa acttagcgaa attccattcg attcgttttc ctagtgggcc agatttatgg
   143161 tcttttaacc agacatagag agggtctgct tccttaccgt tgaccttaat cttggcaaaa
   143221 cgtgggaagg tggtttgaaa atgtaggcta cagaaggcgt tgatttcctc tgcgctgccg
   143281 ggtgcttgtc ccataaactg attgcaaggg aaatccaata tttcgaagcc ctgatcttga
   143341 tagcgttcat agagttcttg aagtccctgg tactggggcg ttaaaccaca tccagtagca
   143401 gtgttgacaa tcaagagaac tttgccacga tagctatcca agggagttgc ttggttgttt
   143461 tggttcaaaa cggaaaaatc ataaagtgaa gtcatgaggg cctcttttct ttttctacat
   143521 tgtaacagtt tttacttttt tcgtcgagtc ggatggaaga tattgttgaa gaataagccc
   143581 tcaatatgat agaaaccgtt tacaaataac tttaaaaatg gtatgattta attaaaccgg
   143641 tttactttgt tgctataaat ctctaatttg agatttagtt cctattgatt ttacaatatg
   143701 tttattggag tgtatatatg caaacaaaaa caaagaagct cattgtgagt ttgtcttcac
   143761 ttgttttatc aggattttta ttaaaccatt atatgacagt tggagcggaa gaaacgacta
   143821 cgaataccat tcagcaaagc cagaaggaag ttcagtatca gcaaagggat acaaaaaatt
   143881 tagttgaaaa tggtgatttt ggtcagacgg aggacggaag cagtccgtgg acaggaagca
   143941 aagctcaggg gtggtcagct tgggtagacc agaagaatag ttctgcagat gcctcaactc
   144001 gagtcattga ggctaaggat ggggctatca ctatctcaag ccatgagaaa ttaagggcag
   144061 cgcttcaccg tatggttcct attgaagcta agaaaaagta taaactgcgt ttcaagatta
   144121 aaacagataa taaagtcggg attgctaaag ttcgtatcat tgaggaaagt ggtaaggaca
   144181 agcgattgtg gaattctgca acgacgtcag gaacaaagga ctggcagacc attgaagcag
   144241 actatagccc gactttagat gttgataaaa tcaagctgga gttattctat gaaacaggaa
   144301 ctgggactgt ttcctttaag gatattgagc tggtagaggt agcagaccag ctttctgagg
   144361 attctcaaac agataaacag cttgaggaaa agattgattt accaattgga aaaaaacatg
   144421 ttttttctct tgcggactat acttataagg tagaaaatcc tgacgttgct tcagtcaaaa
   144481 atggaatttt agaacctctt aaggaaggga caaccaatgt cattgtcagt aaagatggca
   144541 aggaagtgaa aaagattcct ttgaagattc tagcctctgt taaggatgca tacacagccc
   144601 gtttggatga ctggaatggc atcatcgctg ggaatcaata ctatgattct aaaaatgaac
   144661 agatggccaa attaaaccag gaattggaag gaaaggtagc tgatagccta tctagtattt
   144721 caagtcaggc ggaccgcacc tatttgtggg aaaaattttc aaattataaa atgtctgcaa
   144781 atctgactgc cacttatcgg aaattggagg agatggccaa gcaagtgacc aatccttctt
   144841 ctcgttatta tcaagatgaa actgtcgttc gaacagtcag ggattctatg gaatggatgc
   144901 ataaacatgt ctacaatagt gaaaagagca ttgttgggaa ctggtgggat tatgaaatcg
   144961 gtacacctcg tgccatcaac aataccttgt ctctgatgaa agaatacttc tctgatgagg
   145021 aaattaaaaa atatacagat gtaattgaaa aatttgtacc agaccccgaa catttccgaa
   145081 agacgactga taacccattt aaggctctag gtggaaactt agttgatatg ggaagagtaa
   145141 aagtaatagc tggtttactg cgtaaagatg atcaagaaat ttcttctacc attcgctcga
   145201 ttgagcaagt gttcaagttg gtagaccaag gtgaaggttt ttatcaagat ggatcctata
   145261 tcgaccacac caatgttgcc tatacgggtg cttatgggaa tgttttgatt gatggcctgt
   145321 ctcaactgtt gccagtcatt caaaagacca agaatccaat cgataaagat aaaatgcaaa
   145381 ccatgtacca ctggattgat aaatcgtttg ctcctttgct ggtgaatgga gagctgatgg
   145441 atatgagtcg tggacgctcg atcagtcgtg caaatagcga ggggcacgtg gccgcagtag
   145501 aagtactaag agggattcac cgaatagcgg atatgtctga aggagaaacc aaacaacgtt
   145561 tgcagagtct tgtgaagacc attgttcaat cggatagtta ttatgatgtc tttaagaatt
   145621 tgaagactta taaggatatc agtttgatgc aatccttgtt aagtgatgca ggagtcgcaa
   145681 gtgttccaag aacaagttac ctatctgcct ttaacaagat ggataaaaca gccatgtaca
   145741 atgcagagaa agggtttgga tttggcttgt cactcttttc cagtcgtacc ttgaattacg
   145801 aacacatgaa caaggaaaat aaacgtggtt ggtatacgag tgatgggatg ttctatcttt
   145861 acaatggcga tttgagtcac tatagcgatg gctactggcc aacagttaat ccatataaga
   145921 tgcctggtac aacagagacg gatgctaaga gagcggatag cgatacaggt aaagttttac
   145981 cgtctgcttt cgttggaacg agcaaactag atgatgccaa tgcgacagca actatggatt
   146041 tcaccaactg gaatcaaaca ttgactgctc ataagagctg gtttatgcta aaggataaga
   146101 ttgccttttt aggaagcaat atccaaaaca cttcaacaga tactgctgca actacaattg
   146161 accagagaaa actggaatca agtaatccat ataaagtcta tgtcaatgat aaagaagcct
   146221 cccttacaga acaagaaaag gattatcctg aaacccaaag tgtcttttta gaatcgttcg
   146281 attcgaaaaa gaatattggt tactttttct ttaagaagag ttcaatcagt atgagtaagg
   146341 ctttgcaaaa gggagcctgg aaggatatca atgaaggaca gtcagacaag gaagttgaaa
   146401 atgaatttct tacgattagt caggctcata agcaaaatgg agattcttat ggctatatgc
   146461 taattcctaa cgtggatcgt gccaccttca atcaaatgat aaaagagtta gaaagtagcc
   146521 tcatcgacaa taacgaaacc cttcagtctg tttatgatgc taaacaagga gtttggggca
   146581 ttgtgaaata tgatgattct gtctctacta tttccaacca attccaagtt ttgaaacgtg
   146641 gagtctatac cattcgaaaa gaaggggatg aatataagat tgcctactat aatcctgaaa
   146701 cccaggaatc agctccagat caggaagtct ttaaaaagct agagcaagca gctcagccac
   146761 aagtacagaa ttcaaaagaa aaggaaaaat ctgaagagga aaagaaccat tcggatcaaa
   146821 agaatctccc tcagacagga gaaggtcagt caatcttggc aagtctaggg ttcttgctac
   146881 ttggggcatt ttatctattc cgtagaggaa agaacaacta atttgttcat catctagatg
   146941 aattacatga aactgtggaa aatagaaaaa atccgaagaa ggccaaatat cttcggattt
   147001 ttcttttaaa aaaggataag ttgatactta tcctttttta cttcattatt atgtgactat
   147061 agcgttttga aactagaata gaacgttata actgctaaaa gatttctata aattcatttg
   147121 attttcctaa tcaatttgtt cgtatcctat ttcactccac tatataagtc cgtctcgctc
   147181 cgtgaggtgc gcgtcgaagg ttataccaaa aaaactccaa acgcgataca ataaaggtat
   147241 tcaatccaat tgtaaagcga aaggagaaaa aatatggcac aaaagactca tagtttatca
   147301 tacacaaagt ggatgtgttc tatcatattg tgttcacccc taagtataga cgaaaagtca
   147361 tctataatca atatagaagt agtttaggcg aaatatttca tcgcttgtgt agttataaag
   147421 gtgttgaaat gatcgagggt cacttaatgc cagaccatgt acacatgtta gtcagtattc
   147481 cgtcgaggct aagtgtttca agttttatgg ggtatttaaa aggcaaaagt gcactcatga
   147541 tgtttgacaa acacgccaat ctcaagtaca agtttgggaa tcggaatttc tgggcggaag
   147601 gttattatgt aagtccagta gggcttagtg aagccacaat taagaaatat agtcaagatt
   147661 aaagaaatta tcgagtggat gatttcttca cgagtatgaa aatttgagaa ctagtaaagt
   147721 atgatatata gtaaaatgaa ataagaatag gacaaaatcg atcaggacag tcaaatcgat
   147781 ttttaacaat gttttagaag tagaggtata ctattccagt ttcaatctac tatagcacta
   147841 gataaattga gtgtaaaaga atatgaggat ccctttaggg atagtggtaa gtaataccaa
   147901 agtctcttaa agaggcaagt gacgagtcaa gagcaataag gcttgaacaa cgtgaaagcc
   147961 agcgtcttta ggcgctggct gatgatttgg gcttatagct ctgagataaa ccacccgtta
   148021 gacgggtagt tatgatttta tctgagtgta atatactgtt gggcaatctc gctgatgcgg
   148081 tcaaagttgc cttgggaagc gagtttattg agttcgccac caattccaac ggcatctgca
   148141 ccagcagcga accattgagg gatgttgttt aggccgactc ctccggttac cattacggaa
   148201 acttgtggga tcggtgcctt gactgcagag atatatgctg gactgagagt actacctggg
   148261 aagagtttga tgatttcact accggcttca agtgcagtcg tgatctctgt gagggtaata
   148321 cagcctggaa tgtacggtgt gctgtagaga ttgcacattt tcgcagtttc agcatggaaa
   148381 gatggagaaa caacgtaatt tgctccagct agaatggcat ctctagcagt tacggcatca
   148441 agcacagtac ctgcaccgat acaaacactc tgatcgtcct gatacaagtc tacaagttcc
   148501 ttgatgattt gtcctgcata ctgattggta taggcgattt caatagcttt gataccgccc
   148561 ttgatacaag caatcgaggc ttgtagtcct tcttcctttg tatttcctcg aatgacagcg
   148621 acaattttct gtttttttag ttcaataatc gtatctgatt tggtcatgta attctcctaa
   148681 cgaatgatat cttgtgcatt tgccagtaaa ttttcaatac tagttgcgga agtggagaga
   148741 tggtctcctg gaagagtgca tttgagagtt gcgctcgcaa ctgcaaagtc aatggtagtt
   148801 tttagggagg aatgatggag tagttggtaa agggcaccag atataaaggc atccccgcta
   148861 ccaattcgtt gatagactgc agtttttagt tggacagact cttcaaatcg ttcttccaga
   148921 gcataggctt gatagacatt tttgtcttgc tcatcactag atcggagggt atggaaaatg
   148981 gccttgaaac cataggcttc ttttaaaagt cgcatgcgat tttccacctc ttctaggcta
   149041 gcactgtctc ttggaaacat ctctagattt tggtcatcaa tcatgagagg atcaataccg
   149101 aagcaatagt cagtaaaacg tgcaaactta gaaaattcat acttggcttc taggactgaa
   149161 atcatctttg ttctcagatt gagatccatt gaaacgacaa ttcctcggcg cttggcttct
   149221 tccaagagta ggagaaggat cgcacggacc tcttgaccga tagctatggt gattccacta
   149281 aaatgaaaat ggctaatccc ctgaaagaga gaatccatat ctagcatgtt tggccgaatc
   149341 tggctgatac tcgtatgctt acgatcgtag aaaacttcac tttgacgaca accaaagccg
   149401 ttctccaaat agtagaggcc gattcgatcg ccaagccgac agattgaact ggtatcgatt
   149461 tggtgctgtt tcaagaatgt gagaaaacga tctccaatct cgttggcagg gagtgcggta
   149521 aagactttcg ttgagatacc cagggcttgc aaattacaag cgatgttaat ttctgatccg
   149581 ccaaaataag tcgaactggc aacatgatcg ccgatactgg tggcatctaa tggtgagatt
   149641 cgaattaatg gttcgccaaa cagtaatatt ttcgtcatcc attagttcct ttctggttta
   149701 gaatagcttt acttggctaa tacttctttc aaataagcag cgacttcatc atcttggcag
   149761 ttttcaaaga agtattcttg gaagtatttg ccagagatgg tgtctttgag gaagtcttgg
   149821 tcgattgttt taaggatggt catcaaatca ttgtgggtga tttgtttcac ctcgtttaag
   149881 atacgagcgt tacgttgttc agggattaca cgttctcttg ggtagccacc gcccatttct
   149941 tcagcaaata agcgttcaaa catcaatttg agggtcagtt ctgcccccca gccaaatcct
   150001 ttggcataag ggatagacaa ggcgttacca ccattgattt gagaataaag gtaagcgtca
   150061 gttgggtcca ctgctagacc acagacaaca ccagggaagc tgtttaaagc aagcatagcc
   150121 cctacacccg taccacagcc ggtaacaaca aagtcaactg cctttgtatt taaaaggatg
   150181 gcagccatta gtccgttctg cacataagtt aattgacttt ctccttcttc tccacgcata
   150241 ccatagttaa ataattggta gcctttttta tctgtcgctt cttttagact atcgtaaata
   150301 atgtgattct tgctagcttg actattttca ttgattaatg cgattttcat aagatcttct
   150361 ttctattttt actcaggttg ttttccgatg taggctaaga taccgccatc tacatatagg
   150421 atgtggccat tgacaaaatt gctggcatca ctagcgagaa agacagcagg gcccatcaaa
   150481 tcttcagtat ttccccaacg tgcagcaggt gtttttgcaa tgatgaactg gtcaaatggg
   150541 tggcgagaac catcttcttg caattcacga agaggtgctg tttgaggagt ggcaatataa
   150601 cccggtccaa ttccgttaca ttggatattg gctccaccgt attcagacgc aatgttgcgg
   150661 gtcaacattt tcaagccccc tttagcagca gcataagcgc taactgtttc acgtcccagt
   150721 tcgctcatca tcgaacaaat attgataatc tttccatgcc ctttctttat catagaagga
   150781 ataactgcct ttgaaacgat aaatggtgcg tttaagtcaa tatcgatgac cttacggaaa
   150841 tcagcggcgc tcatttcgca cattggaact cggcggataa taccagcgtt attaacgagg
   150901 atgtcaatga caccaacctc ttgttcgatt tgcttgacca tggcttggat accgtcctcg
   150961 tctgtcacgt cacagacata tccatgggct tggatgccaa cttcacgata agcttcaatc
   151021 cctttattga ccagatcttg attgatatcg ttaaagacaa tagtagcgcc ggcttcagcg
   151081 taggatttgg caatagcaaa tccaattcca taagaagcgc cggtgatgag agcaattttt
   151141 ccttttaaag aaaactgctc aattgagaat gatgtatttg tcatttgata cttcctttca
   151201 aatttgttaa gacttctcta taaccaaatt atattctagt aaaccggttt tgtcaataaa
   151261 taaatatttt tatttatgaa aaggtttgtt ttcctaaaaa aacggaagat tttgaaattt
   151321 ctgtctatta aaatggttaa aaagataatg aaagcgctaa tattttttta aaaaaactat
   151381 tgacaagata aaaataaagg attacaatgg ggaatataaa gtaaaccggt aaacctaaaa
   151441 gaaaggagaa aagatgaaaa ttgtacttgt agggcatgga cattttgcta cagggattta
   151501 tagttcttta caattgattg caggtaatca agaaaatgtg gaggcgattg actttgtgga
   151561 aggaatgtca gcagatgaac tcaagcaaaa aatcttactt gcaatttcaa atgaagaaga
   151621 agttttaatc ctaagtgatc tcttgggagg atcgccattc aaggtttctt ctaccataat
   151681 gggagaaaat ccagccaaga caatgaatgt tctctcgggt ttgaacttag ccatgttaat
   151741 ggaagcagtt tttgctagaa tggctcatag ctttgatgag gttgttaata aatcagtagt
   151801 ggcggcccag ggcggagtcg taaatggtaa agaattgttt tcaacggatg cagaggaaga
   151861 ggaagaagat ttcgaatcgg gtatttaaag ggtgaaagaa tgataaaaaa ggttacgatt
   151921 gaagaaataa aatcgcctga gcgcttctta gaagtaccac ttctgacgaa agaagaagtc
   151981 ggccaggcaa tcgataaggt tattcggcag ttagaactca accttgacta tttcaaggaa
   152041 gatttcccga cgccagctac ctttgataat gtctatccaa tcatggataa cacggaatgg
   152101 accaatggtt tctggacagg agaactgtgg ttggcttatg aatacagtca acaggatgca
   152161 tttaaaaaca tcgctcataa aaatgttctt tctttcctgg atcgtgtcaa taagagagta
   152221 gaattggctc accatgatct cggcttcttg tacacaccgt cttgtatggc tgaatataag
   152281 ataaatggag atggagaggc tagagaagca gccttgaaag ctgcagataa gttgattgaa
   152341 cgctatcaag aaaaaggtgg ttttattcaa gcttggggag acttgggcaa gaaagagcat
   152401 taccgtttga ttatcgattg cttgctcaat atccaactct tattctttgc ttatcaagaa
   152461 acaggcgatc aaaaatacta cgatattgca gaaagccatt tctatgcttc agctaataat
   152521 gtaatccgtg atgacgcttc gtccttccac accttctatt ttgatcctga gacaggtcaa
   152581 ccctttaaag gtgtaacgag acaagggtat agtgatgatt catgctgggc acgtggtcag
   152641 tcatggggag tttatggtat tcctttgact tatcgtcact taaaagacga gtcctgcttt
   152701 gacttgttta agggtgtgac caattatttc ttgaatcgtc tgccaaaaga tcatgtgtcc
   152761 tattgggatt tgatttttaa tgatggtagt gatcaatcac gagattcttc agcaacagct
   152821 atcgccgtct gtgggattca tgaaatgcta aaacatctcc cagaggtgga tgctgacaaa
   152881 gatatttata aacatgctat gcatgccatg cttcgttcct tgatcgaaca ttatgcaaat
   152941 gatcaattta cccctggtgg gacaagtctc ctccacggtg tgtactcatg gcattcaggt
   153001 aaaggagtgg atgaaggcaa tatctggggt gactactatt acctagaagc ccttatccgt
   153061 ttctacaaag actggaacct atattggtag gaggagaaat atgacaatgc caaatattat
   153121 tatgacccgt atcgatgaac ggttgattca tggacaagga caactttggg taaaatacct
   153181 aggttgtaat acggtcattg ttgccaatga cgaagtaagc acggacaaga tgcaacaaac
   153241 tctgatgaaa acagttgtgc cagactcagt tgccatgcgt ttcttccctt tgcaaaaggt
   153301 gattgatatc attcacaagg ctaatcctgc tcaaacgatc tttatcgttg taaagaatgt
   153361 gaaggatgct ttaaccttgg tagaaggtgg tgtccctatc aaagaaatca atattgggaa
   153421 cattcacaat gctactggta aagagcaagt gacacgctcc atcttcctgg gtgaagagga
   153481 caaggcagcc ctcaaggaat tgaaccaaac tcatcaagta acatttaata cgaaaacaac
   153541 tccaacagga aatgatggag ctgttcaagt caacattatg gactatattt aaaagaggag
   153601 atcgttatgt cgattaatgt atttcaagcg attttaattg gattatggac agctttctgt
   153661 tttagtggaa tgctgttagg aatttacacc aatagatgta ttgttctgtc atttggtgtc
   153721 ggaattattc taggtgatct gcctactgct cttgcaatgg gagctattgg tgaattggct
   153781 tatatgggat tcggtgttgg tgctggaggt actgttccac caaacccaat cggacctggt
   153841 atctttggta ccttgatggc tatcactagt gctggtaaag tcagtccaga agcggctctt
   153901 gccctctcta ctccgattgc tgtggcgatt caattcttac aaactttcgc ctacactgta
   153961 cgtgctggtg cgcctgaaac ggcgatgaag cacttgaaaa accataattt gaagaaattc
   154021 aagttcactc taaatgcaac aatttggttg tttgccttta ttggatttac cttgggttgc
   154081 ttgggtgccc tttcaatgga taccttgttg aaactcgtag actacattcc accggtattg
   154141 cttacaggtt tgacagttgc tggtaaaatg ctcccagcta tcggttttgc gatgatcttg
   154201 tcagtgatgg ctaagaaaga gttgattccc tttgtcttgt tgggatatgt ttgtgcagct
   154261 tatctaaaca tcccaacaat tggtattgca attgtaggta ctatctttgc tttgattgaa
   154321 ttttataaca agccaaaaac agcggatcat gtggtagagg aggaagcaca cgatgactgg
   154381 atctaacaaa ttaacaaaac gtgattatct taaaacgtct ttgcgggcat tcttttgtca
   154441 aaatggattt aactatagta actatcaagg gttgggatat gccaatgtga tgtatcctgc
   154501 tttgaaaaaa cactatggag aggatcagga aggtttctac caagccttgg aagaaaactg
   154561 tgaattctat aataccaacc cacacttcct gccttttatt accagcttgc atcttgtaat
   154621 gttggaaaat ggccgtccgg caaaagaaac acgtagcatc aagatggcct tgatgggacc
   154681 attggcaggt attggggatt ctctttctca attctgttta gctccattgt tctcaaccat
   154741 cgcagcttcg tttgctcaag aaggcttggt tgtcggtcca atcttgttct tccttgcgat
   154801 gaatacgatt ttaacagcga ttaaattgtc aactggtctg tatggataca aactaggaac
   154861 aactgtgatt gataaactaa gcgaacagat ggcaacgatt tctcgtattg ccaatattat
   154921 cggtgtaacc gtaattgctg gtttggcagc gacatctgtt aagattatgg tgccgattac
   154981 ctttgctgca ggggaagtta aagcagacgc taaacaaagt atcgtaagta ttcagggaat
   155041 gcttgataag gttgctccag ctcttctacc agccctattt acacttttag tttactactt
   155101 gatcaaagaa aagaaatgga caacatataa actcgttatt ttaacagtta tcatcggaat
   155161 tatcggaagc tggcttaaga ttatagctta atggatacaa cattgtttta tggaatagtg
   155221 attgtcttgg cagtgagtcc ccttttactg tcaagctttc attctattcg tcagcaaaag
   155281 ttgcttcgca aacagatgga gcaacgacaa gagtatttag cttctttaac atctggtgat
   155341 gaagtgttgt tattgtctgg aattcatgga aaaatcattt ctatcaaaga tgacttggtc
   155401 tccttgcaga ttgcaaaagg tgtggtcatc tatgtagaaa aggaaagtgt aatgggaaag
   155461 acaaaagaac tgctttttaa gtagttcttt ttctggtaat agataatgaa agaagaaaga
   155521 agacaatttt ttgaaagaat cgatggaaac caatgtcgtg attatatctt gccccactgt
   155581 tcaaaagact atgagaaagt caagagttcc cttgaacgct tgatggacaa tcgttttatg
   155641 tttgatagtc cttgggatat ggagccttgt tcaaaaatcc atcaaatcca gccgatggta
   155701 tgggatcaag tatttgaaga tgatccagaa tgggcttata tgctcaatcg acaagaatat
   155761 ctcttgcagt ttatgatagg gtatctggta gaaggagata agagctatat tcaaaagtgc
   155821 aagttctttc tatttgattg gattgagcag gtgagagaat tttctcctca atccttgatg
   155881 actagaacct tggatacggg tattcgttcc tttacttggt tgaaactact cttgctcctc
   155941 ttgaaatttg acttgctaga ggagaaagaa ctagagaaaa ttttggtcag tctagaaaag
   156001 cagattgact ttatgaaaag ccactatcgc gccaagtaca cccttagtaa ctgggggatt
   156061 ttacaaacaa ttccgatgct tgctatctat tatttctttt cagataagat ggatctagaa
   156121 gaagcttacc attttgcttc agaggagttg aaacagcaaa ttgagacaca gattttagga
   156181 gatggaagcc agtttgaaca gtcgattctc tatcatgtag aggtttataa agccttgctg
   156241 gatttgtgtc tcttgcttcc agacttgcaa gatagttacc gagagttgct ggaaaagatg
   156301 gcgacctata ttcaaatgat gacaggctta gatggacgaa ctttggcttt tggtgatagc
   156361 gattctacag aaacgacaga aattttgagc ctgtctgctg tggttttgaa caaggaagac
   156421 cttcttaacg gtctggatgt taaagtcgat ttgcttagcc tcttgttcct ggggcgagaa
   156481 aaggtcaagc gactgcagga atttgaaagg agagcttggc agcctaagtc catgatcttt
   156541 gaagactctg gacatgtctg cattaaggat gaacatcgtt atctattttt caaaaatggt
   156601 ccgctaggaa gtgcccatag ccatagtgac gagaatagtt tttgcttaca gtatcaaggc
   156661 caacctattt tcatagatgc tgggcgttat tcttatcggg agatatatga acgttatctc
   156721 ttaaagagtg cttggagtca ttcgacctgc attgtagatg ggaaagctcc ggaaagaatc
   156781 acgggatcct gggaatatga atactatcct cactccctgt tttgtcacca taaagaaagg
   156841 gagggagtgc attatattga gggggcttat tggtcagcag aacctgattt gccttatctt
   156901 cacaggagaa aaatcctcat gttggtagag gatgtctggc tcttggtaga tgacatcagg
   156961 tgtcaaggtc agcatgaggc gttgactcag tttatccttg acaaggatgt gacctatcaa
   157021 gatgggaaaa tcaatcagtt gagactatgg agtgaagttg attttgattt ggaagatacc
   157081 atcatttctc ctaaatacaa tgagcttgaa agaagtagca aactcaccaa gcgccaattc
   157141 tttgagaatc agatgctgga ttataccatc attgcgcatg agagttttga aatcatccgt
   157201 cattctgtct accagacaga tgatcgtgaa gtggaaaatg ctctggcttt tgaagtgaaa
   157261 aatgacgaaa cagacaagct gattctgtta ttaagcgagg atattggtgt aggtgaaaaa
   157321 ttgtgcctcg ttgacggaac aaaaatgcgt ggaaaatgtc tagtatatga taaaataaat
   157381 gagagaatga ttcgcttgca gtgctagaaa taggcatttt gaatagtgaa tatgttataa
   157441 taagtattag taggaggtgt tttagattgg agaagaaact gaccataaaa gacattgcgg
   157501 aaatggctca gacctcgaaa acaaccgtgt cattttacct aaacgggaaa tatgaaaaaa
   157561 tgtcccaaga gacacgtgaa aagattgaaa aagttattca tgaaacaaat tacaaaccga
   157621 gcattgttgc gcgtagctta aactccaaac gaacaaaatt aatcggtgtt ttgatcggtg
   157681 atattaccaa cagtttctca aaccaaattg ttaagggaat tgaggatatc gccagccaga
   157741 atggctacca ggtaatgata ggaaatagta attacagcca agagagtgag gaccggtata
   157801 ttgaaagcat gcttctcttg ggagtagacg gctttattat tcagccgacc tctaatttcc
   157861 gaaaatattc tcgtatcatc gatgagaaaa agaagaaaat ggtctttttt gatagtcagc
   157921 tctatgaaca ccggactagc tgggttaaaa ccaataacta tgatgccgtt tatgacatga
   157981 cccagtcctg tatcgaaaaa ggttatgagc attttctctt gattacagcg gatacgagtc
   158041 gtttgagtac tcggattgag cgggcaagtg gttttgtgga tgctttaaca gatgctaata
   158101 tgcgtcacgc cagtctaacc attgaagata agcatacgaa tttggaacaa attaaagaat
   158161 ttttacaaaa agaaatcgat cccgatgaaa aaactctggt atttatccct aactgttggg
   158221 ccctacctct agtctttacc gttatcaaag agttgaatta taacttgcca caagttgggt
   158281 tgattggttt tgacaatacg gagtggactt gcttttcttc tccaagtgtt tcgacgctgg
   158341 ttcagccctc ctttgaggaa ggacaacagg ctacaaagat tttgattgac cagattgaag
   158401 gccgcaatca agaagaaagg caacaagtct tggattgtag tgtgaattgg aaagagtcga
   158461 ctttctaaaa tgaaggaaaa tgacttgcaa tctctgttaa gaaataaaat aatcccacct
   158521 agaacaagct aggtgggatt atttgcctat gaaatgagaa attatgggag caagctccta
   158581 aatcaactgt ttttgatcta cttctttaac tacttgataa aagttataga agtaggccaa
   158641 acttgaaatg atggttacga ctaggaatat tgaaaatttc cattggatag ggttggttaa
   158701 aagttgtgga aaggatatga ggagaaagaa gagggctgcg ttgaggacag gtatccgttt
   158761 tgattgtatt ttctcaagtc ctttattgag cgcaggaaga aagaggagta ggagtagtaa
   158821 aactgtatga gaaacagctc ctgaaataag ggcaaagaaa aggaaaatac tgataaaaac
   158881 atgaatgatc agtagtctag ctagtgattt cataaggtac ctcctaatcc tggtcttttt
   158941 tagctcttgc aatacgaagt gagtcgacaa tatgtatcat cactccgaaa aagaaagctc
   159001 ccagtatagt tttaaaaata tgttttgtat ttagaagaga actgataaaa tttggatttt
   159061 cacttgttag ggtatcaatg agtggaatta taaaaaatat cactgttcca taaatcgaac
   159121 ctgctttcag accaggataa cgtaactgtt tcttttcttt tttcatgagt ttgctccttt
   159181 tttaaaaatc ttcctcccaa aagagactgt tgaggtcagt ttggaggctg cgggcgagat
   159241 tgagacagag ttccaaggtt ggattgtact tgtcgttttc aatcatattg atagtctgtc
   159301 tcgagacacc gatatccttg gcgagttcga gctgggaaat acccaattcc ttgcgaaatt
   159361 ctttcacacg attcatctgg tctcctttct gatttatgtc gtatatattt gactatatta
   159421 tagtctttta aacataaagt gtcaagtatt tttgacatat tttttgaaga aatagtagtc
   159481 tccttgtcct atttgtctga caagtgcaag ctggtcggat ttgtggtaaa atagataaga
   159541 tatgacaaaa gaatttcatc atgtaacggt cttactccac gaaacgattg atatgcttga
   159601 cgtaaaacct gacggtatct acgttgatgc gactttgggt ggagcaggcc atagcgagta
   159661 tttattaagt aaattaagtg aaaaaggcca tctctatgcc tttgaccagg atcagaatgc
   159721 cattgacaat gcgcaaaaac gcttggcacc ttacattgag aagggaatgg tgacctttat
   159781 caaggataac ttccgtcatt tacaggcacg tttgcgcgaa gctggtgttc aggaaattga
   159841 tggaatttgt tatgacttgg gagtgtctag tcctcaattg gaccagcgtg agcgtggttt
   159901 ttcttataaa aaggatgcgc cactggacat gcggatgaat caggatgcta gtctgacagc
   159961 ctatgaagtg gttaatcact atgactatca tgatttggtt cgtattttct tcaaatacgg
   160021 tgaggataaa ttctctaaac agattgcgcg taagattgag caagcgcgtg aagtgaagcc
   160081 gattgagaca acgactgagt tagcagagat tatcaagttg gtcaaacctg ccaaggaact
   160141 caagaagaag ggtcatcctg ctaagcagat tttccaggct attcgaattg aagtcaatga
   160201 tgaactggga gcggcagatg agtccatcca gcaggctatg gatatgttgg ctctggatgg
   160261 tagaatttca gtgattacct ttcattcctt agaagaccgc ttgaccaagc aattgttcaa
   160321 ggaagcttca acagttgaag ttccaaaagg cttgcctttc atcccagatg atctcaagcc
   160381 caagatggaa ttggtgtccc gtaagccaat cttgccaagt gcggaagagt tagaagccaa
   160441 taaccgctcg cactcagcca agttgcgcgt ggccagaaaa attcacaagt aagagggaaa
   160501 aagatggcag aaaaaatgga aaaaacaggt caaatactac agatgcaact taaacggttt
   160561 tcgcgtgtgg aaaaagcttt ttacttttcc attgctgtaa ccactcttat tgtagccatt
   160621 agtattattt ttatgcagac caagctcttg caagtgcaga atgatttgac aaaaatcaat
   160681 gcgcagatag aggaaaagaa aaccgaattg gacgatgcca agcaagaggt caatgaacta
   160741 ttacgtgcag aacgtttgaa agaaattgcc aattcacacg atttgcaatt aaacaatgaa
   160801 aatattagaa tagcggagta agatatgaag tggacaaaaa gagtaatccg ttatgcgacc
   160861 aaaaatcgga aatcgccggc tgaaaacaga cgcagagttg gaaaaagtct gagtttatta
   160921 tctgtctttg tttttgccat ttttttagtc aattttgcgg tcattattgg gacaggcact
   160981 cgctttggaa cagatttagc gaaggaagct aagaaggttc atcaaaccac ccgtacagtt
   161041 cctgccaaac gtgggactat ttatgaccga aatggagtcc cgattgctga ggatgcaacc
   161101 tcctataatg tctatgcggt cattgatgag aactataagt cagcaacggg taagattctt
   161161 tacgtagaaa aaacacaatt taacaaggtt gcagaggtct ttcataagta tctggacatg
   161221 gaagaatcct atgtaagaga gcaactctcg caacctaatc tcaagcaagt ttcctttgga
   161281 gcaaagggaa atgggattac ctatgccaat atgatgtcta tcaaaaaaga attggaagct
   161341 gcagaggtca aggggattga ttttacaacc agtcccaatc gtagttaccc aaacggacaa
   161401 tttgcttcta gttttatcgg cctagctcag ctccatgaaa atgaagatgg aagcaagagc
   161461 ttgctgggaa cctctggaat ggagagttcc ttgaacagta ttcttgcagg gacagacggc
   161521 attattacct atgaaaagga tcgtctgggt aatattgtac ccggaacaga acaagtttcc
   161581 caacgaacga tggacggtaa ggatgtttat acaaccattt ccagccccct ccagtccttt
   161641 atggaaaccc agatggatgc ttttcaagag aaggtaaaag gaaagtacat gacagcgact
   161701 ttggtcagtg ctaaaacagg ggaaattctg gcaacaacgc aacgaccgac ctttgatgca
   161761 gatacaaaag aaggcattac agaggacttt gtttggcgtg atatccttta ccaaagtaac
   161821 tatgagccag gttccactat gaaagtgatg atgttggctg ctgctattga taataatacc
   161881 tttccaggag gagaagtctt taatagtagt gagttaaaaa ttgcagatgc cacgattcga
   161941 gattgggacg ttaatgaagg attgactggt ggcagaatga tgactttttc tcaaggtttt
   162001 gcacactcaa gtaacgttgg gatgaccctc cttgagcaaa agatgggaga tgctacctgg
   162061 cttgattatc ttaatcgttt taaatttggt gttccgaccc gtttcggttt gacggatgag
   162121 tatgctggtc agcttcctgc ggataatatt gtcaacattg cgcaaagctc atttggacaa
   162181 gggatttcag tgacccagac gcaaatgatt cgtgccttta cagctattgc taatgacggt
   162241 gtcatgctgg agcctaaatt tattagtgcc atttatgatc caaatgatca aactgctcgg
   162301 aaatctcaaa aagaaattgt gggaaatcct gtttctaaag atgcagctag tctaactcgg
   162361 actaacatgg ttttggtagg gacggatccg gtttatggaa ccatgtataa ccacagcaca
   162421 ggcaagccaa ctgtaactgt tcctgggcaa aatgtagccc tcaagtctgg tacggctcag
   162481 attgctgacg agaaaaatgg tggttatcta gtcggggtaa ccgactatat tttctcggct
   162541 gtatcgatga gtccggctga aaatcctgat tttatcttgt atgtgacggt ccaacaacct
   162601 gaacattatt caggtattca gttgggagaa tttgccaatc ctatcttgga gcgggcttca
   162661 gctatgaaag actctctcaa tcttcaaaca acagctaaag ctttggagca agtaagtcaa
   162721 caaagtcctt atcctatgcc tagtgtcaag gatatttcac ctggtgattt agcagaagaa
   162781 ttgcgtcgca atcttgtaca acccatcgtt gtgggaacag gaacgaagat taaaaacagt
   162841 tctgctgaag aagggaagaa tcttgccccg aaccagcaag tccttatctt atctgataaa
   162901 gtagaggaag ttccagatat gtatggttgg acaaaggaga ctgctgagac ccttgctaag
   162961 tggctcaata tagaacttga atttcaaggt tcgggctcta ctgtgcagaa gcaagatgtt
   163021 cgtgctaaca cagctatcaa ggacattaaa aaaattacat taactttagg agactaatat
   163081 gtttatttcc ctcagtgctg gaattgtgac atttttacta actttagtag gaattccggc
   163141 ctttatccaa ttttatagaa aggcgcaaat tacaggccag cagatgcatg aggatgtcaa
   163201 acagcatcag gcaaaagctg ggactcctac aatgggaggt ttggttttct tgattacttc
   163261 tgttttggtt gctttctttt tcgccctatt tagtagccaa ttcagcaata atgtgggaat
   163321 gattttgttc atcttggtct tgtatggctt ggtcggattt ttagatgact ttctcaaggt
   163381 ctttcgtaaa atcaatgagg ggcttaatcc taagcaaaaa ttagctcttc agcttctagg
   163441 tggagttatc ttctatcttt tctatgagcg cggtggcgat atgctttctg tctttggtta
   163501 tcaagtgtat ctagggattt tctatattgt cttcgctctt ttctggctag tcggtttttc
   163561 aaacgcagta aacttgacag acggtgttga cggtttagct agtatttccg ttgtgattag
   163621 tttgtctgcc tatggagtta ttgcctatgt gcaaggtcag atggatattc ttctagtgat
   163681 tcttgccatg attggtggtt tgctcggttt cttcatcttt aaccataagc ctgccaaggt
   163741 ctttatgggt gatgtgggaa gtttggccct aggtgggatg ctggcagcta tctctatggc
   163801 tctccaccaa gaatggactc tcttgattat cggaattgta tatgtttttg aaacaacttc
   163861 tgttatgatg caagtcagtt atttcaaact gacaggtggt aaacgtattt tccgtatgac
   163921 gcctgtacat caccattttg agcttggggg attgtctggt aaaggaaatc cttggagcga
   163981 gtggaaggtt gacttcttct tttggggagt gggacttcta gcaagtctcc tgaccctagc
   164041 aattttgtat ttaatgtaag aatggcatcc tgatgtttca gggtgttttt gtatttaaat
   164101 acacaatgaa aatcaaagaa caaactagaa agctaacttt aggctgctca aaatatagta
   164161 gattgaaact agaatagtac acatctactt ctaaaatatt gttagaaatc gatttgactg
   164221 tcctgatcga tttgtcctgt tcttatttca ttttactata cagttttgag atggttgata
   164281 gaactgacga agtcagctca aaacatggtt ttgaggttgt agataaggag aagctgatgt
   164341 ggtttgaaga ggttttcgaa gagtgtaaaa aaatattggt cagttaaagc caaaactatt
   164401 gaccttttct gaccaatgta gtatattatg aacgtaaggt aaatgaaagc cttactagaa
   164461 cacttattta aagtaaaata gaaagaggtg ggtctatgtt tcatctagaa atcttcagaa
   164521 gtaaagatgg tctactcctg cttgaaaaag aaaaaccaga aatagtacgt agggtagcgg
   164581 tttaactagt ctaaattttt taaaacaatg gtcaaagata gtcaatatca gtaatcataa
   164641 ctaagtaaac aaaaagaggt aaagaatatg aataacaact ttaataattt taataacatg
   164701 gatgatttat ttaaccaatt gatgggtggt atgcgaggat atagttctga aaatcgccgt
   164761 tacttaatta atggacgcga agtcacatct gaggaatttg ctcactatcg tgcgactggt
   164821 caattaccag gaaatgcaga aactgatgtg caaatgccac aacaggcatc aggtatgaaa
   164881 caagacggtg tccttgcaaa actaggtcga aacttgacag cagaagcgcg tgagggcaag
   164941 ttggatcctg ttatcggacg aaacaaggaa attcaagaaa catctgaaat cctctcacgc
   165001 cgcaccaaga acaatcctgt tttggtcgga gatgcaggtg ttggtaagac agcagttgtc
   165061 gaaggtctag cgcaagccat tgtgaacgga gatgttcctg ctgctatcaa gaacaaggaa
   165121 attatttcta ttgatatctc aggtcttgag gctggtactc aataccgtgg tagctttgaa
   165181 gaaaatgtcc aaaacttagt caatgaagtg aaagaagcag ggaatattat cctcttcttt
   165241 gatgaaattc accaaattct tggtgctggt agcactggtg gagacagtgg ttctaaagga
   165301 cttgcggata ttctcaagcc agctctctct cgtggagaat tgacagtgat tggggcaaca
   165361 actcaagacg aataccgtaa caccatcttg aagaatgctg ctcttgctcg tcgtttcaac
   165421 gaagtgaagg tcaatgctcc ttcagcagag aatactttta aaattcttca aggcattcgt
   165481 gacctctatc aacaacatca caatgtcatc ttgccagacg aagtcttgaa agcagcggtg
   165541 gattattctg ttcaatacat tcctcaacgt agcttgccag ataaggctat tgaccttgtc
   165601 gatgtaacag ctgctcactt ggcggctcaa catccagtaa cagatgtgca tgctgttgaa
   165661 cgagaaatcg aaacggaaaa agacaagcaa gaaaaagcag ttgaagcaga agattttgaa
   165721 gcagctctaa actataaaac acgcattgca gaattggaaa agaaaatcga aaaccacaca
   165781 gaagatatga aagtgactgc aagtgtcaac gatgtggctg aatctgtgga acgaatgaca
   165841 ggtatcccag tatcgcaaat gggagcttca gatatcgaac gtttgaaaga tatggctcat
   165901 cgcttgcaag acaaggtgat tggtcaagat aaggccgtag aagctgtagc tcgtgctatc
   165961 cgtcgtaacc gtgctggttt tgatgaagga aatcgcccaa tcggcagctt cctctttgta
   166021 gggtctactg gggttggtaa gacggagctt gctaagcaat tggcactcga tatgtttgga
   166081 acccaggatg cgattatccg tttggatatg tctgaataca gtgaccgcac agctgtttct
   166141 aagctaattg gtacaacagc aggctatgtg ggttatgatg acaatagcaa taccttaaca
   166201 gaacgtgttc gtcgcaatcc atactctatc attctcttgg atgaaattga aaaggctgat
   166261 cctcaagtta ttacccttct cctccaagtt ctagatgatg gtcgtttgac agatggtcaa
   166321 ggaaatacag taaacttcaa gaacactgtc attattgcga cctcaaatgc tggatttggc
   166381 tatgaagcca acttgacaga agatgcggat aaaccagaat tgatggaccg tttgaaaccc
   166441 ttcttccgtc cagaattcct caaccgcttt aatgcagtca tcgagttctc acaattgact
   166501 aaggaagacc tttctaagat tgtagatttg atgttggctg aagttaacca aaccttggct
   166561 aagaaagaca ttgacttggt agtcagtcaa gcggctaaag attatatcac agaagaaggt
   166621 tacgacgaag tcatgggggt tcgtcctctc cgtcgcgtgg ttgaacaaga aattcgtgat
   166681 aaggtgacag acttccactt ggatcattta gatgctaaac atctggaagc agatatgaaa
   166741 gatggcgttt tggttattcg tgagaaagcc taagacagaa ttttgaggat aaaaaagaag
   166801 gagccagctg aaaaaactgg ttccttttga ggtacgacgg gcatgtcgta tagtagaagt
   166861 gtactattct agtttcaatc cactatagta gctcagaagt cggtacttaa acgtgctata
   166921 tcaaaaccag tccttgaaaa acgtggattg gtttcgtgtt tggattatta ccttgaacga
   166981 catgcgttaa aagttagttg aaccgccgta tgccgaacag cacgtacggt ggtgtgagag
   167041 gggctagaga ttatccccta ctcgatttta aatcacatga cgttcaaagg catcatctga
   167101 aatcccttgt tccaagatga gttttgccca ttctttagca gagaagaggc tgtggtcctt
   167161 gtagtttccg caagattcga tggttgtccc tgggacatct tcccaagtag tagtttcagc
   167221 gatttccttg agcgaatcct tgataacagc tgcgatttta gcactggtgt gacgtcccca
   167281 cataatcatg tggaagcccg tgcggcaacc aaatggtgaa cagtcaatca tgccgtcaat
   167341 gcggatacgg ataagtttgg ctaagaggtg ctcgatagtg tgaaggccgg cagtagggat
   167401 agagtcttcg tttggctgca ccaagcgaat atcataattg gagatgatgt ctccttttgg
   167461 tcctgtttct tccccaatca agcgaacata gggtgctttg acaatggtgt ggtcaagttc
   167521 aaaactttcg acaataactt cttttgacat ggtaaatcct ttcagttttc ttctctcatt
   167581 atatcataaa ggttgctcct gagacagaga gaaaacctct ccgaggctgg agaggttgaa
   167641 atctttactt acgatataag cggtcgtatt ggtagtatgg gtcaaaggtt acgttgatac
   167701 ccagtttacg aaggacattc ttgtcttcat cagtcaagat gatggttgag tgggcttcgc
   167761 ttcctttgag gttgccgagt tcttccatag cgcgggcagc atcaggattt tctgtagctg
   167821 tgatagcaag tgcaatcagg atttcatttg aatgaaggcg tggattgcgg ctaccgagat
   167881 gatcgatttt aagaccttgg attggcttaa caacttccgg ctcgattaat tttacttctt
   167941 tagcgatgtc agctgatttt ttgatggcgt tgatcaaggc agcggctgta gggccaaaga
   168001 gttctgagtt cttaccagtg acgatttccc catttggcaa ttcaaaggct agggctggtc
   168061 caccagtttc ttctgctttt tggcgcgcaa cgacagcaac cttacggtct gcaggtgtga
   168121 taccgaggtc gttcatgagc aactcaattt tcttgacggc agcttcgcca actttttcag
   168181 ctttgaagtc aagaactgtt tgatagtaac gacggatgat ttcttgttta gaagcttcga
   168241 cagcagcctc gtcatctgta atagcgaaac caaccatgtt gacacccata tctgtcggtg
   168301 aagcgtatgg tgattttccg agaatacgtt ccaacatgcg cttgagcact gggaagattt
   168361 cgatatcacg gttgtagttg acagtggttt ctccataggt ttgaagatgg aaggggtcaa
   168421 tcatgttgac atcatcaagg tcagctgtgg cagcttcata agccaagtta actggatgat
   168481 gaaggggaag attccaaaca gggaaggttt caaatttagc gtagccagac ttgatgccat
   168541 tgatttggtc gtggtacata ttggacatac acgttgccaa ttttccagaa ccgggtccag
   168601 gagcggttac gacaatcaag ttgcgactgg ttttgatgta gtcgtttttg cccatgcctt
   168661 ctggggaaat gatgtgatcc atatccgtcg gatatccttt gattggataa tgaagataag
   168721 aatcaattcc gtttttctca agttggttgc ggaaggcatc tgcagcgggt tggccagcgt
   168781 attgtgtaat gacaacggaa ccaacaaaaa tccctaattc attgaatttg tcaatcaaac
   168841 gaagaacttc ttggtcataa gaaatgccta agtcgccacg tgctttggaa tgttcaatgt
   168901 tgctagcatt aatggcaatc acaacctcaa cctgctcttt caattcttgc aagagcttga
   168961 ttttgttgtc aggttcataa ccaggaagga cacgagcagc gtggaaatct tctaacattt
   169021 tacctccaaa ctctaagtag agcttgccgt caaattggtt aatgcgctcc aaaatatggt
   169081 cgcgttgtaa attcaaatat tgttcagaac taaaagcttg ttttttcatt tttttacctc
   169141 tggactctat tataataaaa aattggaagt taggaaacta cggagctaaa aaagaaatta
   169201 aaaagatcaa gcaaacgctt gcacaaaatt ttaaaaagtg ctatcataga ctatagatta
   169261 tgaaaataat gaggtaaaca gatgcaagaa aaatggtggc ataatgccgt agtctatcaa
   169321 gtctatccaa agagttttat ggatagtaat ggagatggaa ttggcgattt gccaggaatt
   169381 accagtaagt tggactatct agccaagcta ggaatcacag caatttggct ttctcccgtt
   169441 tatgacagcc ctatggatga taatggctac gatattgctg attatcaagc gattgcaacg
   169501 atttttggaa ccatggagga tatggatcaa ctgattgcag aagctaagaa gcgtgatatc
   169561 cgtatcatca tggacttggt ggtcaatcat acctcggatg agcatgcctg gtttgtagag
   169621 gcctgtgaaa atcctaatag ccctgagcga gactactata tctggcgcga tgaacccaat
   169681 gacctagatt ctatctttag tgggtctgct tggaaatacg atgaaaagtc aggtcaatac
   169741 tatctccact ttttcagcaa gaagcagccg gatctcaact gggaaaatga aaaacttcgc
   169801 cagaaaattt atgagatgat gaacttctgg attgataaag gtattggtgg tttccgtatg
   169861 gatgttattg acatgattgg caaaattcct gacgagaagg tagtcaataa tggtcctatg
   169921 ctccatccct atctcaagga aatgaatcag gcgacctttg gagataagga tctcttgaca
   169981 gtaggggaga cttggggagc aacgccagag attgccaagc tctactctga tccaaagggg
   170041 caagaattgt ctatggtctt ccagtttgaa catatcggtc ttcagtatca ggaaggtcag
   170101 cctaaatggc actatcaaaa agagctgaat atcgctaagt taaaagaaat cttcaacaaa
   170161 tggcagacag agttaggagt tgaggacggc tggaattccc tcttctggaa caaccatgac
   170221 ctccctcgta ttgtctcaat ctggggaaat gaccaagaat accgcgaaaa atctgccaaa
   170281 gcctttgcaa tcttgcttca tcttatgaga ggaactcctt atatctacca aggtgaggag
   170341 attgggatga ccaactatcc gtttgaaaca ctggatcaag tagaagatat tgaatctctc
   170401 aactatgcgc atgaggctct tgaaaaaggt attccgattg aagaaatcat ggacagtatc
   170461 cgtgttattg gacgtgacaa tgctcgtacc cctatgcaat gggacgagag caaaaacgct
   170521 ggtttctcaa caggtcaacc ttggttggcg gttaatccaa attacgagat gatcaatgtc
   170581 caagaagcgc tggcaaatcc agattctatt ttctatacct atcagaaact ggtccaaatt
   170641 cgcaaggaga atagctggct aattcgagct gactttgaat tgcttgatac ggctgataag
   170701 gtctttgctt atatacgtaa ggatggcgac cgtcgcttcc tagttgtggc taacttgtcc
   170761 aatgaagagc aagacttgac agtagaagga aaagtcaaat ctgtcttgat tgaaaacact
   170821 gcggctaaag aagtacttga aaaacaggtc ttggctccat gggatgcttt ctgtgtggaa
   170881 ttactataaa tattttttgc agaaaaattt aaaattgaaa tcgtataaaa acaagggaag
   170941 actgtataaa aggcagaaat cctttgtttt ttataaccaa ggtttataaa ccttcattct
   171001 cgaaattcaa ttaactttac aaattcccac tattaaggag aaagaagacg aacataaaga
   171061 agcgtatcct tagtgcaggc ctgactttta catctgattt gcttttagct gcttgcggcc
   171121 aatcaggttc agatacaaaa acttactcat caacctttag tggaaatcca actacattta
   171181 actatctatt agactattac gctgataata tagtcaattg aaacaagaac a
//
LOCUS       DBERPV010000002        96887 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.02, whole genome shotgun sequence.
ACCESSION   DBERPV010000002 DBERPV010000000
VERSION     DBERPV010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 96887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 96887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..96887
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.02"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..150)
                     /locus_tag="ACL8C7_000183"
     CDS             complement(<1..150)
                     /locus_tag="ACL8C7_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
                     /protein_id="HGS1394458.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASHVFQISRNTIYGWLKLKEK
                     TGELNH"
     gene            403..1848
                     /gene="cps4A"
                     /locus_tag="ACL8C7_000184"
     CDS             403..1848
                     /gene="cps4A"
                     /locus_tag="ACL8C7_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HGS1394459.1"
                     /translation="MSRRFKKSSSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     IDQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIINSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRTDLPSY
                     AMPDSNLYVLEIDDSSLAVVKAAIQDVMEGR"
     gene            1850..2581
                     /gene="cps4B"
                     /locus_tag="ACL8C7_000185"
     CDS             1850..2581
                     /gene="cps4B"
                     /locus_tag="ACL8C7_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HGS1394460.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRIIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLEKKRIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QVNSSHVLKPKLFGERYKFMKKRAQYFLEQDLVHVIASDMHNLDGRPPHMAEAYDLVT
                     QKYGEAKAQELFIDNPRKIVMDQLI"
     gene            2590..3282
                     /gene="cpsC"
                     /locus_tag="ACL8C7_000186"
     CDS             2590..3282
                     /gene="cpsC"
                     /locus_tag="ACL8C7_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HGS1394461.1"
                     /translation="MKEQNTIEIDVFQLFKTLWKRKLMILIVALVTGAGAFAYSTFIV
                     KPEYTSTTRIYVVNRDQGDKPGLTNQDLQAGSYLVKDYREIILSQNVLEKVATNLKLD
                     MPTKTLASKVKVTVPTDTRIVSISVKDKQPEEASRIANSLREVAAEKIVAVTRVSDVT
                     TLEEARPATTPSSPNVRRNSLFGFLGGAVVTVIAVLLIELLDTRVKRPEDVEDVLQIP
                     LLGVVPDLNKMK"
     gene            3292..3981
                     /locus_tag="ACL8C7_000187"
     CDS             3292..3981
                     /locus_tag="ACL8C7_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HGS1394462.1"
                     /translation="MPTLEISQAKLDFVKKAEEYYNALCTNLQLSGDDLKVFSITSVK
                     LGEGKSTTSTNIAWAFAHAGYKTLLIDGDIRNSVMLGVFKARDKITGLTEFLSGTTDL
                     SQGLCDTNVENLFVIQAGSVSPNPTALLQSKNFSTMLETLRKYFDYIIVDTAPVGVVI
                     DAAIITRKCDASILVTEVGEINRRDIQKAKEQLEHTGKPFLGVVLNKFDTSVDKYGSY
                     GNYGDYGKNKK"
     gene            3997..5364
                     /locus_tag="ACL8C7_000188"
     CDS             3997..5364
                     /locus_tag="ACL8C7_000188"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGS1394463.1"
                     /translation="MNGKIVKSSLAIIQSFLVILLTYLLSAVREAEIVSTTAIALYIL
                     HYFVFYISDYGQDFFKRGYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LTLHALLVYVLNLFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDRLIESNEVVGEL
                     VAVSVLDKPDFQHDCLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDRSLARNKQIREMAGLNVVTFSTTFYKTSHVIAKRIIDIMGALVGLIL
                     CGLVSIVLVPLIRKDGGSAIFAQTRIGKNGRQFTFYKFRSMCVDAEAKKRELMEQNTM
                     QGGMFKVDDDPRITKIGCFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPE
                     QKRRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVAYIDDWTIWKDIEILLKTVKVVLM
                     KDGAK"
     gene            5395..6567
                     /gene="cps2T"
                     /locus_tag="ACL8C7_000189"
                     /gene_synonym="wchF"
     CDS             5395..6567
                     /gene="cps2T"
                     /locus_tag="ACL8C7_000189"
                     /gene_synonym="wchF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta 1-4 rhamnosyltransferase Cps2T"
                     /protein_id="HGS1394464.1"
                     /translation="MKQSVYIIGSKGIPAKYGGFETFVEKLTEYQKDGNIQYYVACMR
                     ENSAKSGFTADTFEYNGAICYNIDVPNIGPARAIAYDIAAVNKAIELSKGNKDEAPIF
                     YILACRIGPFISGLKKKIRSIGGRLLVNPDGHEWLRAKWSLPVRKYWKFSEQLMVKHA
                     DLLVCDSKNIEKYIREDYKQYQPKTTYIAYGTDTTPSSLKSEDAKVRNWYREKGVSEN
                     GYYLVVGRFVPENNYETMIREFIKSKSNKDFVLITNVEQNKFYDQLLKETGFDKDLRV
                     KFVGTVYDQELLKYIRENAFAYFHGHEVGGTNPSLLEALASTKLNLLLDVGFNREVGE
                     DGAIYWKKDELAHVIEEVERFDEGDITELDEKSSQRIADAFTWEKIVSDYEEVFTV"
     gene            6564..7847
                     /locus_tag="ACL8C7_000190"
     CDS             6564..7847
                     /locus_tag="ACL8C7_000190"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGS1394465.1"
                     /translation="MKILHYTLGFQPSRTGGLVKYAEDLMTQQATDGHEVIALYPGEI
                     SIIFRQVRIKKAENRKFQCYKIINSLPLALFGGISEPDEFMKSCDKASYRKFLKNIKV
                     DVIHIHSLIGLHKEFIEVAKELGIKTVFTSHDYYGLAPVPHFYFNGVDYSSNNTNLAW
                     NIMSSNALSVKKLRFFQVSFYPTIRKLMKMLGKNPKSKKNLVIRDITEAIDYSALRSY
                     YKAMFGLIDAYLFNSQLAKEVYEANHIIPKNNIIVSISNSSISNHNIRVSSGEKTVVA
                     YIGPDEEYKGYFDFLDIVNDLDQEKYDIKTYGHFPNEDCPPYIQQNGYFTKDTVGSVY
                     SNIDILIVPSRWKETFGLISIEALSYDVNVFVSKNVGSKDLVSEEHIFHNKDDLLKKI
                     QYVKFENVKFKTMKEHMVEIINYYERITNDNQKIN"
     gene            7810..8514
                     /locus_tag="ACL8C7_000191"
     CDS             7810..8514
                     /locus_tag="ACL8C7_000191"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HGS1394466.1"
                     /translation="MKGLQMIIKRLIKTITGKEIDLHPDIPITYILQRGFQYGLGLSR
                     GLLRGIGLGKKGKRLFIGRGVTLLAKRKLYVGNNIRIGKYVSIDCLSKDGIQIADNVK
                     IGDYSQIIGTGSVKNMGIGLKIGKNSSFSEYSLFGSAGGITIGGDVIAGQNVRFHAEN
                     HSYEVLHIPIREQGVNRKGISVGDNCWIGAGAVFLDGSSIGSGCIVATNAVVTKKFPD
                     NVIIGGVPAKILMERK"
     gene            8558..9793
                     /locus_tag="ACL8C7_000192"
     CDS             8558..9793
                     /locus_tag="ACL8C7_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HGS1394467.1"
                     /translation="MKIAVVGTGYVGLSISVLLAQHHHVVAVDIVKEKVELINKRISP
                     IQDDFIERYLSESNLDLVATIDAETAYKDASFIVVATPTNYDLERNFFDTSTVESVIQ
                     QVQNMNSTATIVIKSTVPVGFTDSIRKKLGISNLLFSPEFLRESRALYDNLYPSRIIV
                     GTDLSNQKLVEKAQVFSNLLVQGAIKKDIPILTMGFTEAEAVKLFANTYLALRVSYFN
                     ELDTYAEIKGLDTQKIIEGVSLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYKNVPE
                     ELIGAIVRSNTTRKDFIANQVLKVVNYNIPEDDIPTKQMEKEVVIGIYRLTMKSNSDN
                     FRQSSIQGVMKRIKDRGVKVIIFEPTLKDSDTFFGNAVINDLEEFKVKCDVIIANRYD
                     ETLNDVKDKVYTRDIFRRD"
     gene            9801..10925
                     /locus_tag="ACL8C7_000193"
     CDS             9801..10925
                     /locus_tag="ACL8C7_000193"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGS1394468.1"
                     /translation="MKKVLIVRSGPYQVNPEGYNLQELGLASAISQQGYQCDVMYYHK
                     TKNYDQLYEKNGEQIKIFWRRGIRLFRSGIYPQILREKFLNQYDKIIISEYSQIMAVL
                     LSRIHSNVYIYNGPYYNLFKIPIIEPIYDFLFVEMLNKRTKTVFCKTEKAECYLKNKG
                     FNDCKVVGVGLDIEKFEQEEEPTEDTIELLRRMENKQNILYVGSLSKRKNTAQLIRIF
                     NILKSKSGKKSELQLVLIGKDEDNIVEKINYSRFKDDIIYQPYLKNSQLQFIYPSSQL
                     LVLPSVQEIFGMVLLEAMYFKLPVVSSASAGGETLIQDGINGKIVNDFNDEHWVDCIE
                     NLLNNPLELKRLGECAHKRITEQFMWSSIARKIIETFDER"
     gene            10949..11776
                     /locus_tag="ACL8C7_000194"
     CDS             10949..11776
                     /locus_tag="ACL8C7_000194"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGS1394469.1"
                     /translation="MILHYRTSNDTIECIKSIQKLEGDYKIVIVDNASQNGSIERVEA
                     LFANNDEIVIIKNTKNLGFAAGNNIGYAYARTQIKADMIAVLNNDIVIKQKDFINRIF
                     ELYRNSQFHIAGPDIVSLVDGHHQSPVVEKINSISKANKELFKYRILRIINKIGLYEL
                     MTRQPKKELNRISVADPMRYQENVILHGSFVIFSPLYVSEEECAFRPDTFMYMEEPIL
                     YEYCMLKNYKTVFDPSIVIYHKEDSSTNSLYNAAYAKREFVFKNMIRSLKIYRSLLK"
     gene            11818..13086
                     /locus_tag="ACL8C7_000195"
     CDS             11818..13086
                     /locus_tag="ACL8C7_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008755 - O antigen polymerase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polymerase"
                     /protein_id="HGS1394470.1"
                     /translation="MLALTIGTVVFVKKTYRTFLNPIILFVILWFIITTLSSLKLFQL
                     FEISTHTQQIILLGTSLFVIGGGIAIWFRDKFYFKVGGNSYFTTDFEINYNLFFLLGI
                     ICLFYYLPDFFSSLVSLIRGGNLNLVRQSAQDAVDTSGLKNFIGTFIVSPSAMVLEIL
                     GVLDFWSNKKGRKLFYLSLAVIFVRVIADAGRTPLFNVVIYLLLTVLANRFSEKTEKK
                     RKVSKIKIVNYGMLGSIILWLSTLSRTTTSVYRILYFYFAMSPILLEKWSSVLDSEKL
                     VTKGLVSLNGFFFSISYVLKNLFRIDYSQRVLEAYTMIANTDAIWYNIAPGLTKANAY
                     VSLFWFFYADGRLLGVLIGSLLYGTFCGYIFCRYIQQQNKKNLAMLLFIYQGVFFSFI
                     RFPFSKSNYAIAFVLLLFFAFKKKGIEKSV"
     gene            13079..14086
                     /locus_tag="ACL8C7_000196"
     CDS             13079..14086
                     /locus_tag="ACL8C7_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394471.1"
                     /translation="MFNINDQSIIYVACPYFNKTGGTELVHQLVYSINHFGGKAIVAY
                     YGSESAPNKVNPAFREYVSTFVDIKDVIDSLDNIIILPEINPDLAANLESIQKAVWWM
                     SVDNYLKRNGILGSLEHFGLLRTIKLFVKGNIKIGGYRIDKEIPHLYQSEYAKQFLLA
                     KGVKKYYRLSDYLNESYIQRSISTDTKKDVILYNPKKGIEFTRELIKQAPELTFSPIE
                     NMSTEQVKKLLSKSKVYIDFGNHPGKDRFPREAAISGCCVITGKRGSAKYYKDIPIPD
                     SYKFEDTVENIPNIIETLKSCLKNYDKHTVDFEKYQQYIKSEHDLFERDVKELFTRNR
                     G"
     gene            14091..15533
                     /locus_tag="ACL8C7_000197"
     CDS             14091..15533
                     /locus_tag="ACL8C7_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000107550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140327 - flippase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="HGS1394472.1"
                     /translation="MSTRNSLIKNSLYNVAYRMLNIIFPLVSATYTARIILASGVGEV
                     SFAQNVVSYFTTIAAMGIPNYGIREIAKTRNKAEATNKVFSELFLINGLSTLLCSIVY
                     LILILTFNSIFDNTSMYLAVGLTLVFNFLNIDWFYQGKEDYAYITKRSFSIKLISLFS
                     LFIFVRDTDDAVNYALISSLAIGGNNIFNLVNLRKYNIRFSFNNIKIRRHLKPIFVLL
                     GSVIAIEIYTMLDTTMIGAMVGTTEVGYYTNSMKLVKLLITVITAIGGVLLPRLSDYY
                     SKGEFEKLNHIVDKVFRIMLFLFLPAQVALILVAPVIMPILFGDSFIPAVLTLQLTSL
                     LICTLGFSNLFGTQILLTFGDERKLLISTILGALSNIALNLILIPVMAQNGAALASVI
                     SETIVTLTAYYYAKKRVTIRFDLGFYLPTVVSTIIMGGAIYVVMQLYIGDIEKMLFST
                     LLGGVVFLLINVFMKNPIIYEFTGIIKRKR"
     gene            15536..16636
                     /gene="glf"
                     /locus_tag="ACL8C7_000198"
     CDS             15536..16636
                     /gene="glf"
                     /locus_tag="ACL8C7_000198"
                     /EC_number="5.4.99.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008767 - UDP-galactopyranose mutase
                     activity [Evidence IEA];
                     GO_process: GO:0009273 - peptidoglycan-based cell wall
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
                     /protein_id="HGS1394473.1"
                     /translation="MYDYLIVGAGLSGAIFAHEATKRGKKVKVIDKRDHIGGNIYCEN
                     VEGINVHKYGAHIFHTSNKKVWDYVNQFAEFNNYINSPVANYKGSLYNLPFNMNTFYA
                     MWGTKTPQEVKDKIAEQTAGMKDVEPKNLEEQAIKLIGPDIYEKLIKGYTEKQWGRSA
                     IELPPFIIKRLPVRLTFDNNYFNDRYQGIPIGGYNVIIENMLKDVEVELGVDFFAHRE
                     ELEASANKVVFTGMIDQYFDYKHGELEYRSLRFEHEILDEENYQGNAVVNYTEREIPY
                     TRIIEHKHFEYGMQPKTVITHEYPADWKRGDEPYYPINDEKNNAMFAKYQEEAAQNDK
                     VIFCGRLADYKYYDMHVVIERALEVVEKEFSN"
     gene            16663..17532
                     /gene="rfbA"
                     /locus_tag="ACL8C7_000199"
     CDS             16663..17532
                     /gene="rfbA"
                     /locus_tag="ACL8C7_000199"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HGS1394474.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLPRFKELLQDGSEFGIKLSYAEQPSPDGLAQAFIIGEEFISDDSV
                     ALILGDNIYHGSGLSKMLQKAASKESGATVFGYHVKDPERFGVVEFDQDMKAISIEEK
                     PEQPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLTLAQPLKKN
                     EYGQYLLRLIGEA"
     gene            17533..18126
                     /locus_tag="ACL8C7_000200"
     CDS             17533..18126
                     /locus_tag="ACL8C7_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018029578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HGS1394475.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKHHPLLKDVKPLKKEDL"
     gene            18139..19188
                     /gene="rfbB"
                     /locus_tag="ACL8C7_000201"
     CDS             18139..19188
                     /gene="rfbB"
                     /locus_tag="ACL8C7_000201"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HGS1394476.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPGVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            19254..20105
                     /gene="rfbD"
                     /locus_tag="ACL8C7_000202"
     CDS             19254..20105
                     /gene="rfbD"
                     /locus_tag="ACL8C7_000202"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HGS1394477.1"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITNEEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNVAKASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     gene            20202..21354
                     /locus_tag="ACL8C7_000203"
                     /pseudo
     CDS             20202..21354
                     /locus_tag="ACL8C7_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013641878.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            21553..23535
                     /locus_tag="ACL8C7_000204"
     CDS             21553..23535
                     /locus_tag="ACL8C7_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS1394478.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNLFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVQFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDETTDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            23837..29140
                     /locus_tag="ACL8C7_000205"
     CDS             23837..29140
                     /locus_tag="ACL8C7_000205"
                     /EC_number="3.2.1.97"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033926 -
                     endo-alpha-N-acetylgalactosaminidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SpGH101 family
                     endo-alpha-N-acetylgalactosaminidase"
                     /protein_id="HGS1394479.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVANKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTKNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDESKLLSSISF
                     LGNALVSVSSNQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRDNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGQGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FESLDAPAQPGEGLENAFDGNVSSLWHTSWGGGDVGKPATMVLKEATEITGLRYVPRG
                     SGSNGNLRDVKLVVTAESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKSDAPTVEKPEFKLSSLASEQGKTPDYKQEID
                     RPETPEQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
     gene            complement(29307..31466)
                     /gene="pbp1a"
                     /locus_tag="ACL8C7_000206"
     CDS             complement(29307..31466)
                     /gene="pbp1a"
                     /locus_tag="ACL8C7_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1A"
                     /protein_id="HGS1394480.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLTYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(31463..32059)
                     /gene="recU"
                     /locus_tag="ACL8C7_000207"
     CDS             complement(31463..32059)
                     /gene="recU"
                     /locus_tag="ACL8C7_000207"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HGS1394481.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            32125..32652
                     /locus_tag="ACL8C7_000208"
     CDS             32125..32652
                     /locus_tag="ACL8C7_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HGS1394482.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            32722..33051
                     /gene="gpsB"
                     /locus_tag="ACL8C7_000209"
     CDS             32722..33051
                     /gene="gpsB"
                     /locus_tag="ACL8C7_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HGS1394483.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            33072..33452
                     /gene="rnpB"
                     /locus_tag="ACL8C7_000210"
     ncRNA           33072..33452
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACL8C7_000210"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            33537..34694
                     /locus_tag="ACL8C7_000211"
     CDS             33537..34694
                     /locus_tag="ACL8C7_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HGS1394484.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVERELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            34707..36101
                     /gene="mapZ"
                     /locus_tag="ACL8C7_000212"
     CDS             34707..36101
                     /gene="mapZ"
                     /locus_tag="ACL8C7_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HGS1394485.1"
                     /translation="MSKKRRNRHKKEAQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTNSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLVTQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            36177..37601
                     /gene="gndA"
                     /locus_tag="ACL8C7_000213"
     CDS             36177..37601
                     /gene="gndA"
                     /locus_tag="ACL8C7_000213"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HGS1394486.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVSDVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEDQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            37613..38302
                     /locus_tag="ACL8C7_000214"
     CDS             37613..38302
                     /locus_tag="ACL8C7_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS1394487.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELKVVQRFAVSYIY
                     KPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            38401..39303
                     /locus_tag="ACL8C7_000215"
     CDS             38401..39303
                     /locus_tag="ACL8C7_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HGS1394488.1"
                     /translation="MKLLKKMMPIALAVFFFGLLATSTVFADTMGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIHGTGYRDDLFDNRPVFEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKKTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDPATGIM
                     QTGWQFLGNRWYYLRSSGAMATGWYQDGSTWYYLDPSNGDMKIGWTKVNGNWYYLNSS
                     GAMVTGSQTIDGKVYNFASSGEWI"
     gene            39321..40319
                     /gene="cbpJ"
                     /locus_tag="ACL8C7_000216"
     CDS             39321..40319
                     /gene="cbpJ"
                     /locus_tag="ACL8C7_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpJ"
                     /protein_id="HGS1394489.1"
                     /translation="MKILKKTMQVGLTVFFFGLLGTSTVFADDSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDSLSGEMVVGWQYIPFPSKGSTIGPYPNGIRLEGFPKS
                     EWYYFDKNGVLQEFVGWKTLEIKTKDSVGRKYGEKREDSEDKEEKRYYTNYYFNQNHS
                     LETGWLYDQSNWYYLAKTEINGENYLGGERRAGWINDDSTWYYLDPTTGIMQTGWQYL
                     GNNWYYLRSSGAMATGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSSGAMATGW
                     YQDGSTWYYLNAGNGDMKTGWFQVNGKWYYAYGSGALAVNTTVDGYSVNYNGDWVR"
     gene            complement(40438..41670)
                     /locus_tag="ACL8C7_000217"
     CDS             complement(40438..41670)
                     /locus_tag="ACL8C7_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGS1394490.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEVVPLLSQLFLGILGDFQENRVKHALWIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILYQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAYIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(41713..42300)
                     /locus_tag="ACL8C7_000218"
     CDS             complement(41713..42300)
                     /locus_tag="ACL8C7_000218"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="HGS1394491.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCGIAY
                     ALFAYSKVLEPSMFYNDLHTFHTELKKLLEKVTSNTENLGNLQLSWCEGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKIQQVILA
                     CSERDDHGLLMFQGDSGKADLFDFGIGSRGYIGVY"
     gene            complement(42200..42538)
                     /locus_tag="ACL8C7_000219"
                     /pseudo
     CDS             complement(42200..42538)
                     /locus_tag="ACL8C7_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811282.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic-modifying protein"
     gene            43200..43529
                     /locus_tag="ACL8C7_000220"
     CDS             43200..43529
                     /locus_tag="ACL8C7_000220"
                     /inference="COORDINATES: protein motif:HMM:NF024736.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS1394492.1"
                     /translation="MTRKAYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMIPHDFPLYLTVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVN
                     YNGEWVQ"
     gene            43651..44529
                     /gene="mvk"
                     /locus_tag="ACL8C7_000221"
     CDS             43651..44529
                     /gene="mvk"
                     /locus_tag="ACL8C7_000221"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HGS1394493.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            44511..45464
                     /gene="mvaD"
                     /locus_tag="ACL8C7_000222"
     CDS             44511..45464
                     /gene="mvaD"
                     /locus_tag="ACL8C7_000222"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HGS1394494.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            45451..46458
                     /locus_tag="ACL8C7_000223"
     CDS             45451..46458
                     /locus_tag="ACL8C7_000223"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HGS1394495.1"
                     /translation="MIAVKTCGKLYLAGEYAILEPGQLALIKDIPIYMRADIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFFAVRGQNLRPFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKIAAWLKEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLTSSKETVVFLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVTKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            46442..47452
                     /gene="fni"
                     /locus_tag="ACL8C7_000224"
     CDS             46442..47452
                     /gene="fni"
                     /locus_tag="ACL8C7_000224"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HGS1394496.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEINLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            47529..48227
                     /gene="liaF"
                     /locus_tag="ACL8C7_000225"
     CDS             47529..48227
                     /gene="liaF"
                     /locus_tag="ACL8C7_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HGS1394497.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAVTILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSNYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            48224..49219
                     /locus_tag="ACL8C7_000226"
     CDS             48224..49219
                     /locus_tag="ACL8C7_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGS1394498.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENQSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            49233..49865
                     /locus_tag="ACL8C7_000227"
     CDS             49233..49865
                     /locus_tag="ACL8C7_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGS1394499.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            49941..50635
                     /locus_tag="ACL8C7_000228"
                     /pseudo
     CDS             49941..50635
                     /locus_tag="ACL8C7_000228"
                     /inference="COORDINATES: protein motif:HMM:NF020296.4"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            50785..51024
                     /locus_tag="ACL8C7_000229"
     CDS             50785..51024
                     /locus_tag="ACL8C7_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394500.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            51105..51699
                     /gene="cbpG"
                     /locus_tag="ACL8C7_000230"
                     /pseudo
     CDS             51105..51699
                     /gene="cbpG"
                     /locus_tag="ACL8C7_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
     gene            52001..52393
                     /locus_tag="ACL8C7_000231"
     CDS             52001..52393
                     /locus_tag="ACL8C7_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGS1394501.1"
                     /translation="MDSPKSLASYRVIGIIDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNSFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPITAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNITEKLDKLVLESD"
     gene            52554..53837
                     /gene="tig"
                     /locus_tag="ACL8C7_000232"
     CDS             52554..53837
                     /gene="tig"
                     /locus_tag="ACL8C7_000232"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HGS1394502.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDQKFGEEALYQDAMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVITAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     ATAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(53885..56251)
                     /locus_tag="ACL8C7_000233"
     CDS             complement(53885..56251)
                     /locus_tag="ACL8C7_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HGS1394503.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLKTIQKHITTIEKELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(56485..57099)
                     /gene="lepB"
                     /locus_tag="ACL8C7_000234"
     CDS             complement(56485..57099)
                     /gene="lepB"
                     /locus_tag="ACL8C7_000234"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HGS1394504.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            complement(57103..57984)
                     /gene="rnhC"
                     /locus_tag="ACL8C7_000235"
     CDS             complement(57103..57984)
                     /gene="rnhC"
                     /locus_tag="ACL8C7_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HGS1394505.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            58071..58373
                     /gene="zapA"
                     /locus_tag="ACL8C7_000236"
     CDS             58071..58373
                     /gene="zapA"
                     /locus_tag="ACL8C7_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HGS1394506.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            58370..58918
                     /locus_tag="ACL8C7_000237"
     CDS             58370..58918
                     /locus_tag="ACL8C7_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HGS1394507.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            59022..61358
                     /locus_tag="ACL8C7_000238"
     CDS             59022..61358
                     /locus_tag="ACL8C7_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HGS1394508.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKAV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     regulatory      61521..61609
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            61700..63022
                     /locus_tag="ACL8C7_000239"
     CDS             61700..63022
                     /locus_tag="ACL8C7_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HGS1394509.1"
                     /translation="MLELLKSIDAFTWGPPLLILLVGTGVYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     gene            63240..63788
                     /locus_tag="ACL8C7_000240"
     CDS             63240..63788
                     /locus_tag="ACL8C7_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HGS1394510.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            63898..64797
                     /locus_tag="ACL8C7_000241"
     CDS             63898..64797
                     /locus_tag="ACL8C7_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HGS1394511.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPNWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(64822..66096)
                     /gene="serS"
                     /locus_tag="ACL8C7_000242"
     CDS             complement(64822..66096)
                     /gene="serS"
                     /locus_tag="ACL8C7_000242"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HGS1394512.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSATKTY
                     DLEVWIPAQNNYREISSCSNTEDFQSRRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(66310..66681)
                     /locus_tag="ACL8C7_000243"
     CDS             complement(66310..66681)
                     /locus_tag="ACL8C7_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HGS1394513.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            complement(66684..68048)
                     /locus_tag="ACL8C7_000244"
     CDS             complement(66684..68048)
                     /locus_tag="ACL8C7_000244"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HGS1394514.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAADSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRELTPIKEEEILRQLVQKTKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            68417..69202
                     /locus_tag="ACL8C7_000245"
     CDS             68417..69202
                     /locus_tag="ACL8C7_000245"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HGS1394515.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            69296..69730
                     /locus_tag="ACL8C7_000246"
     CDS             69296..69730
                     /locus_tag="ACL8C7_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGS1394516.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            69730..70704
                     /locus_tag="ACL8C7_000247"
     CDS             69730..70704
                     /locus_tag="ACL8C7_000247"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HGS1394517.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            70764..70988
                     /locus_tag="ACL8C7_000248"
     CDS             70764..70988
                     /locus_tag="ACL8C7_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGS1394518.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            71107..72081
                     /gene="fabK"
                     /locus_tag="ACL8C7_000249"
     CDS             71107..72081
                     /gene="fabK"
                     /locus_tag="ACL8C7_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018580 - nitronate monooxygenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HGS1394519.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            72074..72994
                     /gene="fabD"
                     /locus_tag="ACL8C7_000250"
     CDS             72074..72994
                     /gene="fabD"
                     /locus_tag="ACL8C7_000250"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HGS1394520.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            73028..73759
                     /gene="fabG"
                     /locus_tag="ACL8C7_000251"
     CDS             73028..73759
                     /gene="fabG"
                     /locus_tag="ACL8C7_000251"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HGS1394521.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            73781..75016
                     /gene="fabF"
                     /locus_tag="ACL8C7_000252"
     CDS             73781..75016
                     /gene="fabF"
                     /locus_tag="ACL8C7_000252"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HGS1394522.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            75019..75504
                     /gene="accB"
                     /locus_tag="ACL8C7_000253"
     CDS             75019..75504
                     /gene="accB"
                     /locus_tag="ACL8C7_000253"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HGS1394523.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVASEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            75501..75923
                     /gene="fabZ"
                     /locus_tag="ACL8C7_000254"
     CDS             75501..75923
                     /gene="fabZ"
                     /locus_tag="ACL8C7_000254"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0019171 -
                     (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HGS1394524.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            75935..77302
                     /gene="accC"
                     /locus_tag="ACL8C7_000255"
     CDS             75935..77302
                     /gene="accC"
                     /locus_tag="ACL8C7_000255"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0004075 - biotin carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HGS1394525.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            77339..78205
                     /gene="accD"
                     /locus_tag="ACL8C7_000256"
     CDS             77339..78205
                     /gene="accD"
                     /locus_tag="ACL8C7_000256"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HGS1394526.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            78202..78969
                     /locus_tag="ACL8C7_000257"
     CDS             78202..78969
                     /locus_tag="ACL8C7_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HGS1394527.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            79128..79313
                     /gene="briC"
                     /locus_tag="ACL8C7_000258"
     CDS             79128..79313
                     /gene="briC"
                     /locus_tag="ACL8C7_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HGS1394528.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            79331..79804
                     /locus_tag="ACL8C7_000259"
     CDS             79331..79804
                     /locus_tag="ACL8C7_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394529.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            79859..80053
                     /locus_tag="ACL8C7_000260"
     CDS             79859..80053
                     /locus_tag="ACL8C7_000260"
                     /EC_number="3.4.26.-"
                     /inference="COORDINATES: protein motif:HMM:NF014566.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HGS1394530.1"
                     /translation="MILSHRDPISLLYYSLIGFFFALVYRSTDNLRLTILCHSFFNFL
                     NHAKPIWIFVYNYIYYHFFR"
     gene            complement(80103..80525)
                     /gene="nusB"
                     /locus_tag="ACL8C7_000261"
     CDS             complement(80103..80525)
                     /gene="nusB"
                     /locus_tag="ACL8C7_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HGS1394531.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(80518..80907)
                     /locus_tag="ACL8C7_000262"
     CDS             complement(80518..80907)
                     /locus_tag="ACL8C7_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGS1394532.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            complement(80929..81489)
                     /gene="efp"
                     /locus_tag="ACL8C7_000263"
     CDS             complement(80929..81489)
                     /gene="efp"
                     /locus_tag="ACL8C7_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HGS1394533.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            complement(81618..83060)
                     /gene="gatB"
                     /locus_tag="ACL8C7_000264"
     CDS             complement(81618..83060)
                     /gene="gatB"
                     /locus_tag="ACL8C7_000264"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HGS1394534.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            complement(83060..84526)
                     /gene="gatA"
                     /locus_tag="ACL8C7_000265"
     CDS             complement(83060..84526)
                     /gene="gatA"
                     /locus_tag="ACL8C7_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HGS1394535.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQTTLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            complement(84526..84828)
                     /gene="gatC"
                     /locus_tag="ACL8C7_000266"
     CDS             complement(84526..84828)
                     /gene="gatC"
                     /locus_tag="ACL8C7_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HGS1394536.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            85041..86585
                     /locus_tag="ACL8C7_000267"
     CDS             85041..86585
                     /locus_tag="ACL8C7_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HGS1394537.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLELLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            87013..87210
                     /locus_tag="ACL8C7_000268"
     CDS             87013..87210
                     /locus_tag="ACL8C7_000268"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394538.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNV"
     gene            87321..87497
                     /locus_tag="ACL8C7_000269"
     CDS             87321..87497
                     /locus_tag="ACL8C7_000269"
                     /inference="COORDINATES: protein motif:HMM:NF013652.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGS1394539.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     NGMWRAENVTQDLI"
     gene            87613..87801
                     /gene="rpmB"
                     /locus_tag="ACL8C7_000270"
     CDS             87613..87801
                     /gene="rpmB"
                     /locus_tag="ACL8C7_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HGS1394540.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            87958..88323
                     /locus_tag="ACL8C7_000271"
     CDS             87958..88323
                     /locus_tag="ACL8C7_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGS1394541.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            88326..89993
                     /locus_tag="ACL8C7_000272"
     CDS             88326..89993
                     /locus_tag="ACL8C7_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HGS1394542.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            90194..91894
                     /locus_tag="ACL8C7_000273"
     CDS             90194..91894
                     /locus_tag="ACL8C7_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HGS1394543.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            91887..92363
                     /gene="ilvN"
                     /locus_tag="ACL8C7_000274"
     CDS             91887..92363
                     /gene="ilvN"
                     /locus_tag="ACL8C7_000274"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1990610 - acetolactate synthase regulator
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HGS1394544.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            92429..93451
                     /gene="ilvC"
                     /locus_tag="ACL8C7_000275"
     CDS             92429..93451
                     /gene="ilvC"
                     /locus_tag="ACL8C7_000275"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HGS1394545.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVVEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            93558..93794
                     /locus_tag="ACL8C7_000276"
     CDS             93558..93794
                     /locus_tag="ACL8C7_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394546.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            94032..94388
                     /locus_tag="ACL8C7_000277"
     CDS             94032..94388
                     /locus_tag="ACL8C7_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HGS1394547.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            94438..95688
                     /gene="ilvA"
                     /locus_tag="ACL8C7_000278"
     CDS             94438..95688
                     /gene="ilvA"
                     /locus_tag="ACL8C7_000278"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004794 - threonine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HGS1394548.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            96558..96773
                     /locus_tag="ACL8C7_000279"
     CDS             96558..96773
                     /locus_tag="ACL8C7_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394549.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNHEKFED"
BASE COUNT        29419 a        17209 c        21690 g        28569 t
ORIGIN      
        1 gtggtttagc tctcctgttt tctcttttag ctttaaccag ccataaatgg tattacgtga
       61 gatttggaaa acgtgtgatg cttctgttat actacctgtt cgctcacaat aagagagaac
      121 ttttttacga aaatctattg aatatgccat aaaaagatta taccacattg tgtactatat
      181 tatattgaaa ctagaatagt acacatctgc ttctaaaata ttgttagaaa acgatttgac
      241 tgtcctgatc aatttgtcat gttcttattt cattttacta tatttttggt tcgcgggaag
      301 tctactaaga tacttaaaga tgcagatagt gaaaataaag gtgtagacat taccgtaaaa
      361 aagtgatata atcgtatgat gttcaatgta taggtgttaa tcatgagtag acgttttaaa
      421 aaatcaagtt cacagaaagt gaagcgaagt gttaatatag ttttgctgac tatttattta
      481 ttgttagttt gttttttatt attcttaatc tttaagtaca atatccttgc ttttagatat
      541 cttaatctag tggtaactgc gttagtccta ctagttgcct tggtagggct actcttgatt
      601 atctataaaa aagctgaaaa atttactatt tttctgttgg tgttctctat ccttgtcagc
      661 tctgtgtcgc tctttgcagt acagcagttt gttggactga ccaatcgttt aaatgcgact
      721 tctaattact cagaatattc aatcagtgtc gctgttttag cagatagtga gatcgaaaat
      781 gttacgcaac tgacgagtgt gacagcaccg actgggactg ataatgaaaa tattcaaaaa
      841 ctactagctg atatcaagtc aagtcagaat accgatttga cgatcgacca gagttcgtct
      901 tacttggcag cttataagag tttgattgca ggggagacta aggccattgt cttaaatagt
      961 gtctttgaaa atatcatcga gtcagagtat ccagactatg catcgaagat aaaaaagatt
     1021 tataccaagg gattcactaa aaaagtagaa gctcctaaga cgtctaagaa tcagtctttc
     1081 aatatctatg ttagtggaat tgacacctat ggccctatta gttcggtgtc gcgatcagat
     1141 gtcaatatcc tgatgactgt caatcgagat accaagaaaa tcctcttgac cacaacgcca
     1201 cgtgatgcct atgtaccaat cgcagatggt ggaaataatc aaaaagataa attaacccat
     1261 gcgggcattt atggagttga ttcgtccatt cacaccttag aaaatctcta tggagtggat
     1321 atcaattact atgtgcgatt gaacttcact tctttcttga aaatgattga cttattggga
     1381 ggggtagatg ttcataatga tcaagagttt tcagctctac atgggaagtt ccatttccca
     1441 gtagggaatg tccatctaga ctctgagcag gctctaggtt ttgtacgtga acgctactca
     1501 ctagccgatg gagaccgtga ccgtggtcgc aaccaacaaa aggtgattgt ggctatcctt
     1561 caaaaattaa cgtcaaccga agcactgaaa aattatagta cgatcattaa tagcttgcaa
     1621 gattctatcc aaacaaatat gccacttgag actatgataa atttggtcaa tgctcagtta
     1681 gaaagtggag ggaattataa agtaaattct caagatttaa aagggacagg tcggacggat
     1741 cttccttctt atgcaatgcc agacagtaac ctctatgtgt tggaaataga tgatagtagt
     1801 ttagctgtag ttaaagcagc tatacaggat gtgatggagg gtagatgaaa tgatagacat
     1861 ccattcgcat atcgtttttg atgtagatga cggtcccaag tcaagagagg aaagcaaggc
     1921 tctcttggca gaatcctaca ggcaaggggt acgaatcatt gtctctacct ctcaccgtcg
     1981 caagggcatg tttgaaactc cggaagagaa gatagcagaa aactttcttc aggttcggga
     2041 aatagctaag gaagtggcga gtgacttggt cattgcttac ggagctgaaa tttactacac
     2101 accagatgtt ctggataagc tggaaaaaaa gcggattccg accctcaatg atagtcgtta
     2161 tgccttgata gagtttagta tgaacactcc ttatcgcgat attcatagcg ccttgagcaa
     2221 gatcttgatg ttgggaatta ctccagtcat tgcccacatt gagcgctatg atgctcttga
     2281 aaataatgaa aaacgcgttc gagaactgat cgatatgggc tgttacacgc aagtaaatag
     2341 ttcacatgtc ctcaaaccca aactttttgg cgaacgttat aaattcatga aaaaaagagc
     2401 tcagtatttt ttagagcagg atttggttca tgtcattgca agtgatatgc acaatctaga
     2461 cggtagacct cctcatatgg cagaagcata tgaccttgtt acccaaaaat acggagaagc
     2521 gaaggctcag gaacttttta tagacaatcc tcgaaaaatt gtaatggatc aactaattta
     2581 ggagaaatga tgaaagaaca aaacacgata gaaatcgatg tatttcaatt atttaaaacc
     2641 ttgtggaaac gcaagctaat gattttaata gtggcacttg tgacaggtgc gggggctttt
     2701 gcatatagca cttttattgt taagccagaa tatacgagta ccacgcgaat ttacgtagtg
     2761 aatcgcgatc aaggagacaa gccggggctg acaaatcagg atttgcaggc aggatcttat
     2821 ctggtaaaag actaccgtga gattatcctt tcgcagaatg tattggaaaa agtagcgaca
     2881 aatttgaagt tggatatgcc aacaaaaacg ttagccagca aagttaaagt gactgtacca
     2941 actgacactc gtatcgtctc aatctctgtc aaagataaac aaccagaaga agccagtcgt
     3001 atcgctaatt ctctacgaga agttgctgca gaaaagatcg tcgctgtaac gcgagtatct
     3061 gatgtaacga cacttgaaga agcgcgacca gctacgactc cctcttctcc aaatgttcga
     3121 cgcaattcct tgtttggttt tcttggagga gcagtcgtaa cagtaattgc tgttcttttg
     3181 attgagttgc tcgacacccg tgtgaaacgt cctgaagatg tcgaagatgt actgcaaatt
     3241 ccacttttag gggtcgttcc agatttgaac aaaatgaaat aggaggaagt tatgccaaca
     3301 ttagaaatct cacaggcaaa attggatttt gtaaaaaagg cagaggaata ttataacgct
     3361 ttgtgcacga acctacagtt aagtggagat gatttgaaag tattttctat cacttctgtg
     3421 aaactaggag aaggaaaatc aacgacttcc accaatatcg cttgggcttt tgcgcatgca
     3481 ggttacaaaa cgctgctgat tgatggagat attcgcaatt ctgttatgtt aggtgtcttt
     3541 aaagcaaggg ataagattac aggcctgaca gaatttttat caggaactac agacctatca
     3601 caagggcttt gtgataccaa tgtcgaaaat ctctttgtaa ttcaggctgg ctctgtgtca
     3661 ccgaatccga cagctcttct tcaaagtaag aatttcagta caatgcttga aaccttgcgt
     3721 aaatattttg actacatcat tgtagatact gctcctgtcg gtgtcgtgat tgatgcggct
     3781 attattacgc gaaaatgcga tgcttctatt ttagtgacgg aggtaggtga aataaatcga
     3841 cgggatattc aaaaagcaaa agaacagttg gaacacacag gaaagccgtt tttgggagtt
     3901 gtgttgaata aattcgatac ttcagtagac aaatacggtt cttatggaaa ttatggagat
     3961 tacgggaaaa ataaaaaata ggtcggggga ttagagatga atggaaaaat agtaaagtct
     4021 tcattggcca taatccagag ttttcttgtt attttattga cttatctact tagtgctgtg
     4081 agagaagcgg agattgtttc aacaacagct attgcacttt atatcctcca ttattttgtc
     4141 ttttatatca gtgattatgg acaggatttc tttaaaagag gatatttgat tgaacttgtc
     4201 cagacattga aatatatcct attctttgca ctagcgatta gtatttctaa ttttttctta
     4261 gaggatcgat ttagtatttc cagacgaggc atgatttact tcctcacatt acatgctctc
     4321 ttagtctatg tgctaaacct atttatcaag tggtattgga agcgggctta tcccaacttt
     4381 aaaggaagta agaagattct cctacttaca gcaacttctc gtgtcgaaaa ggtactggat
     4441 agattaatag aatcaaatga ggttgttggg gagttggtag ccgtcagtgt cttagataaa
     4501 ccagattttc agcatgattg tttaaaggta gtagcagagg gggagatagt aaactttgcg
     4561 actcatgagg tggtcgatga agtctttatc aatcttccaa gtgaaaaata caatattgga
     4621 gagcttgtct ctcagtttga aacgatggga attgatgtaa cagttaatct aaatgctttt
     4681 gatcgtagtt tggcacgtaa caagcaaatt cgtgagatgg caggattaaa cgttgtgact
     4741 ttttctacaa cattttataa gactagtcat gtaattgcta agcggattat tgatatcatg
     4801 ggtgcattgg tagggctgat actatgtggt ttagtcagta ttgtactggt tcctttgatt
     4861 cgaaaggatg ggggctctgc tatttttgct cagacgcgta taggaaaaaa tggtcgtcag
     4921 ttcacttttt ataagtttcg ctctatgtgt gtagatgccg aggcgaaaaa aagagaactc
     4981 atggaacaaa ataccatgca gggtggaatg tttaaggtgg acgatgatcc tcgtatcacg
     5041 aaaattggtt gttttatacg gaagactagc ttggacgagc taccacagtt ttataatgtt
     5101 ctaaagggag atatgagttt ggttggcaca cggccaccaa cagtggacga gtatgagcac
     5161 tataccccag aacaaaagcg tcgtctgagt tttaaacctg gcataacagg gttatggcag
     5221 gtcagcggac gaagtgagat taagaatttt gatgaagttg tcaaattaga tgtagcctat
     5281 atagacgatt ggacaatttg gaaagatatt gaaattttat tgaagacagt taaagttgta
     5341 ttgatgaagg atggagcgaa gtgatttttg cccttcggtc ttgttaggag agatatgaaa
     5401 cagtcagttt atatcattgg ttcaaagggg attcctgcca agtatggagg atttgaaacc
     5461 tttgttgaga aattaacaga atatcaaaaa gatggtaaca tccaatacta tgttgcttgc
     5521 atgcgcgaaa attctgcaaa gtcaggattt acagcagaca catttgagta caacggtgct
     5581 atttgttaca acattgatgt gcctaatatt ggtcctgcta gagccattgc ttacgatatt
     5641 gcagcggtca ataaggctat tgaattgtct aagggaaaca aggacgaggc tcccattttt
     5701 tacattctag cttgtcgtat cggacctttt atttctggac ttaagaaaaa aattcgttcg
     5761 atcggaggcc gtttgctggt aaatccagat ggtcatgagt ggcttcgagc taaatggagc
     5821 ttgccagttc ggaagtattg gaaattttcg gaacagttga tggtcaaaca tgcagattta
     5881 ttagtctgcg atagcaaaaa tatcgaaaaa tatattcgag aggactataa acagtatcag
     5941 cccaagacga cctatatcgc ttatggtaca gatactaccc cttcaagtct gaaatcagaa
     6001 gatgccaaag ttcgaaactg gtatcgtgaa aagggagtaa gcgaaaatgg ctattatcta
     6061 gtggtgggac gattcgttcc cgaaaacaac tatgaaacca tgattcgtga atttatcaag
     6121 tctaagtcca ataaggactt tgtccttatt acaaatgtgg aacagaataa attttacgat
     6181 cagttgctca aggaaacagg tttcgacaag gatctaagag tcaaatttgt gggaacagtc
     6241 tatgaccaag aattgctcaa gtatatccgt gaaaatgctt tcgcctattt ccatggacat
     6301 gaagttgggg gtaccaatcc atcgcttctt gaagctttag catccactaa actcaacttg
     6361 ttgttggatg tcggctttaa ccgtgaagtt ggtgaagacg gagccattta ttggaaaaaa
     6421 gatgagctag cgcatgtaat cgaagaagtg gaacgatttg atgaaggtga tattacggaa
     6481 ttagacgaaa agtctagcca acgaattgcg gatgcattta cgtgggaaaa gattgtgtca
     6541 gattatgagg aagtgtttac tgtatgaaaa ttttgcatta tactttaggc tttcaaccat
     6601 cacgtacagg tggtcttgtc aagtatgctg aggatttgat gactcaacaa gctacagatg
     6661 gacatgaagt aatcgcatta tatccaggag aaatctcaat tatatttagg caggttagaa
     6721 taaaaaaagc agagaatcga aaattccaat gctataaaat aataaacagc ctacccttgg
     6781 ctctatttgg tggtatttca gaaccagatg aatttatgaa gagttgtgat aaagcttctt
     6841 ataggaaatt tttgaaaaat attaaggtag atgtaattca cattcactcg cttataggat
     6901 tacataagga atttattgaa gttgcaaaag aattaggaat taaaactgta tttacaagcc
     6961 atgattatta tggtttagcg ccagttccgc atttttattt taacggagta gattatagta
     7021 gtaataatac taatttagca tggaacatca tgtcctctaa tgctcttagt gtaaaaaaac
     7081 ttcgattctt tcaagtctct ttttacccaa caattcggaa attgatgaaa atgcttggga
     7141 aaaatccaaa gtccaagaaa aacttagtaa ttcgtgatat cacggaggct attgattata
     7201 gtgctctccg ctcttattat aaagcaatgt ttgggttaat agatgcttac cttttcaata
     7261 gtcagttagc taaggaagtt tatgaagcta atcatataat acctaaaaac aatatcatag
     7321 tgtccatttc taacagctca ataagtaatc ataatattcg tgttagttcc ggtgagaaaa
     7381 cagtggtagc ttatattggg cctgatgagg aatataaggg gtattttgat tttctagata
     7441 tagttaatga tttagatcag gaaaagtatg atattaaaac atatggacat tttccaaatg
     7501 aagattgtcc accttatatc caacagaacg gttatttcac aaaagacacg gttggaagcg
     7561 tttattccaa tatagatatt ttgattgtgc cgagtaggtg gaaggaaaca tttggtttga
     7621 ttagtataga ggcgctatcg tatgatgtga atgtttttgt gagcaaaaat gtgggctcta
     7681 aagatttggt ttcagaagaa catatctttc ataataaaga cgatttgtta aaaaaaattc
     7741 aatatgtaaa attcgagaat gtaaaattca aaacgatgaa agagcatatg gtggagatta
     7801 taaattacta tgaaaggatt acaaatgata atcaaaagat taattaagac aattacaggt
     7861 aaagaaattg atcttcaccc tgatatccca ataacttaca ttcttcagag aggttttcaa
     7921 tacggtttgg gtcttagtcg agggttgtta cgtggtattg gtctaggaaa aaaaggcaaa
     7981 cgattattta ttggacgtgg ggtaaccctt ctcgcaaaac gcaagttata tgttggaaac
     8041 aatatccgaa tcggcaaata tgtgagcata gattgccttt caaaggatgg gatccaaatt
     8101 gcggataatg ttaagatagg agattactcg caaataattg gtacaggttc agtaaaaaat
     8161 atgggtattg ggctcaaaat tggaaagaac tcttctttct cagaatatag tttattcggt
     8221 tctgcaggtg ggattactat cggaggagat gttattgctg gacaaaatgt acgttttcat
     8281 gctgagaatc atagctacga agtgttgcat ataccaatca gagagcaagg tgttaatcgt
     8341 aaagggatat ccgttggtga caattgctgg attggggcag gagctgtttt tttagatgga
     8401 tctagtatcg gttcaggttg tatcgttgca acgaatgcgg ttgttactaa gaaatttcca
     8461 gataatgtaa ttattggtgg agtgccagct aaaattttaa tggaaagaaa gtagtattaa
     8521 attaattgta taaatggagg gaaatgatat gtctaaaatg aagattgctg tagttgggac
     8581 aggttatgtt ggtttatcca tttctgtgtt acttgcacaa caccatcatg tagtagcagt
     8641 agatattgta aaagagaaag tagaattaat taataaaaga atttcaccta ttcaggatga
     8701 ttttattgaa agatatcttt cagaaagtaa tttagattta gttgcaacaa tagacgctga
     8761 aacagcttat aaagatgcct cttttatcgt agtagcgaca ccaacaaatt atgacttaga
     8821 aagaaatttt tttgatacat caacagttga atcggtcatt caacaagttc agaatatgaa
     8881 ttctacagca actatagtaa taaaatcaac agtccccgtg ggctttaccg attcaattcg
     8941 taaaaaatta ggaatttcaa atcttctatt cagtcctgaa tttttgcgtg aatcaagggc
     9001 actttatgat aacttatatc caagtcggat catagttgga acagatttaa gtaatcaaaa
     9061 attagttgaa aaagcccaag ttttctctaa tcttttagtg caaggtgcca ttaaaaaaga
     9121 tatccctatt ttaactatgg gatttactga agctgaagca gttaaattat ttgctaatac
     9181 ctacttagca ttgcgggtat catattttaa tgaattagat acttatgcag agatcaaagg
     9241 gttagatact caaaaaataa ttgaaggtgt tagtttagat cctcgtatcg gaacccatta
     9301 taataatccg agctttgggt atggtggata ttgcttacca aaggatacta agcaactttt
     9361 agccaattat aagaatgtcc cagaagagct tattggagct atagtacgaa gcaatacaac
     9421 acgtaaagat tttattgcta atcaagttct taaagtggtg aattataata taccagaaga
     9481 cgatattcct actaaacaga tggagaaaga agttgttatt ggaatatacc gattaactat
     9541 gaaaagtaac agtgataact ttcgtcagag ttcaatacaa ggagttatga aacgtattaa
     9601 ggatagagga gttaaagtaa tcatttttga gcctactcta aaagatagtg atacattctt
     9661 tggaaacgct gttataaatg atttagaaga gttcaaagta aagtgtgatg tgattattgc
     9721 aaatcgttat gatgaaacgt tgaatgacgt taaggataaa gtatatacac gagatatttt
     9781 tagaagagat tgataaaaat atgaaaaaag tattaattgt tcgaagtgga ccttaccaag
     9841 tcaatccgga aggatataat cttcaagaac ttggtttagc ctccgctatc agtcagcaag
     9901 gctaccagtg tgatgtcatg tattatcaca aaacaaagaa ctatgatcaa ttatatgaga
     9961 aaaatgggga acaaattaaa atattctgga ggaggggaat aagattattt agaagtggaa
    10021 tttatcccca gattttaaga gagaaatttt tgaatcagta tgataagata attatttctg
    10081 agtacagcca gattatggca gttttattgt ctagaattca ttccaatgta tatatttata
    10141 atggcccata ctataatcta tttaagattc ccattattga acctatatac gattttcttt
    10201 ttgtagaaat gctcaataag agaaccaaaa cagttttctg caagacagaa aaagcagagt
    10261 gttatcttaa aaacaaagga ttcaatgatt gtaaagtagt gggcgtaggt ctagatattg
    10321 agaagtttga acaagaagag gaacctacag aggatactat agagctttta agaagaatgg
    10381 agaataaaca aaatattctt tatgtaggtt cactatcaaa aagaaaaaac acagctcagt
    10441 taattagaat ttttaatatt ttaaaatcta aaagtggtaa gaaaagtgaa cttcaattgg
    10501 tattgattgg taaggatgag gataatattg ttgaaaaaat taactattca cggtttaaag
    10561 atgatattat ttatcaacct tatttaaaga attctcagct tcaatttatt tacccatcat
    10621 cacaactact tgtgctcccg tcagttcaag agatttttgg tatggtatta cttgaggcaa
    10681 tgtattttaa gttgcctgtt gtttccagtg caagtgctgg aggagagaca ctgattcaag
    10741 atggtataaa cggtaaaatt gtgaatgatt ttaatgatga acactgggtg gattgtatag
    10801 aaaatctatt aaataaccca ttggaattga aacggcttgg agaatgtgct cataagcgca
    10861 ttacggaaca gtttatgtgg tcttcaattg cgagaaaaat aattgagaca tttgatgaaa
    10921 ggtaagactt gctatgaatt tttgttttgt gattttgcat tatcgtacca gcaatgacac
    10981 tatagagtgt atcaaatcga ttcaaaagct tgagggagat tataaaattg taattgttga
    11041 taatgcttct caaaatggca gtatagaaag ggtagaagcc ttatttgcaa ataatgacga
    11101 gatagttata ataaaaaaca cgaaaaactt aggatttgct gctggaaata atattggata
    11161 cgcctacgct aggactcaaa taaaagctga tatgattgct gtacttaata atgatattgt
    11221 tattaagcaa aaagatttca tcaatcgtat atttgaactc tatagaaatt ctcagtttca
    11281 tatcgctggt ccagacattg tctctcttgt agatggtcat catcaaagtc ctgttgttga
    11341 gaagattaat tctatatcta aggctaataa agaacttttt aaatatagaa tcttgaggat
    11401 tattaataaa ataggattat atgagctgat gactagacag ccaaaaaaag aattaaatag
    11461 aataagtgtt gcagacccta tgagatatca ggaaaatgtt attttacatg ggagttttgt
    11521 aattttttca ccgttgtatg tttcagagga ggagtgtgct ttcagaccgg atacattcat
    11581 gtatatggaa gagcctattc tatatgaata ttgcatgctt aaaaattata agacagtatt
    11641 tgatccttct attgtaattt atcataaaga ggactcatca acaaattcgt tgtataatgc
    11701 agcatatgca aaaagagagt ttgtttttaa aaatatgatt agatctctaa agatttatag
    11761 aagtctattg aagtagtaaa ctaaggaaag gataataatt agaaattgaa tcttagtatg
    11821 ttagccttga caataggaac agtggtattt gttaaaaaaa cgtataggac gtttctcaat
    11881 cccataattt tatttgtaat tttgtggttt attataacaa ctttgtcaag tttaaaacta
    11941 ttccaacttt tcgagattag tactcacaca caacaaatta ttttgcttgg gacttctcta
    12001 tttgttatag ggggagggat agcaatttgg tttcgggata aattttattt taaagttggc
    12061 ggtaactcat attttacaac agactttgaa attaattata atttgttctt tttgctaggt
    12121 atcatttgcc ttttctatta tttgccagat ttcttttcct cactggtatc attaataaga
    12181 ggtgggaatt taaacttagt tagacaatct gcgcaggatg cagtagatac cagtggatta
    12241 aagaatttca ttggaacatt tattgttagt cctagtgcca tggtattaga aatattagga
    12301 gtattagatt tctggagcaa taaaaaaggt agaaaactat tttatcttag tttagctgtc
    12361 atttttgtaa gagttattgc agatgctggt agaacacctc tatttaatgt tgtcatatat
    12421 ttattactta ctgttttagc aaataggttc tctgaaaaaa ctgaaaagaa gagaaaagtt
    12481 agtaaaatta agatagtaaa ttatggtatg ctaggttcaa ttatcttatg gctatcaact
    12541 ttatctagga caacaacctc cgtttatagg attctttatt tttatttcgc aatgtcccca
    12601 atattattag aaaagtggag tagtgtactt gattctgaaa aattagtaac aaagggtttg
    12661 gtttcgttga acggtttctt tttttcaatc tcatatgtac ttaaaaatct gtttagaata
    12721 gattattcgc aaagagtatt agaagcatac acaatgattg cgaatactga tgcaatctgg
    12781 tataatattg cacctggttt gaccaaggca aatgcatatg tctctctgtt ttggttcttt
    12841 tatgcggatg gacgtttact aggagtttta ataggatccc ttctatatgg taccttttgt
    12901 ggttatatct tttgcaggta tatccagcaa caaaataaaa agaatttggc tatgttacta
    12961 tttatttatc aaggtgtttt tttctctttt attagatttc cgttttcaaa atcaaattat
    13021 gcaattgcat tcgtactctt attatttttt gcttttaaga agaaaggaat agagaaaagt
    13081 gtttaatatc aatgaccagt ctattattta tgttgcatgt ccttatttta ataaaacagg
    13141 tggaacggag cttgtccatc aattagttta ttctattaat cattttgggg ggaaagctat
    13201 cgttgcttat tatggtagtg aaagtgctcc aaataaggtg aatcctgcgt ttagagaata
    13261 tgtttctacg tttgttgata taaaagatgt tattgactct cttgataata ttattatttt
    13321 accggaaatt aatccggatt tagctgctaa tctagagtct attcaaaaag cagtatggtg
    13381 gatgagcgtt gacaattatt tgaagcgtaa tggtatttta ggttccttgg aacattttgg
    13441 acttttacga acaattaaat tatttgtaaa aggaaatatt aaaataggtg gatatagaat
    13501 agataaagag attccccatc tttatcaaag tgaatacgcc aagcaatttc ttctagctaa
    13561 aggtgtcaaa aagtactata gattgtctga ttatttaaac gagtcttata ttcagcgatc
    13621 tatttcaaca gacactaaaa aagatgttat tctttacaat cctaaaaaag ggattgaatt
    13681 tactcgtgag ctaattaaac aggctccaga attaacgttc tctccaattg agaatatgtc
    13741 aactgaacag gtgaaaaaat tactttcaaa aagcaaagta tatattgatt ttggcaacca
    13801 tcctgggaaa gatagattcc cacgggaggc agcgatatca ggttgttgtg tgataactgg
    13861 gaaacgaggt tctgcaaaat attataagga tattcctatt ccagattcat acaaatttga
    13921 agacactgtt gaaaatatcc ccaacattat tgagaccctg aaatcatgct taaaaaatta
    13981 tgacaaacat actgttgact ttgagaaata tcaacaatat attaaatctg aacatgattt
    14041 atttgaaaga gatgtgaaag aattattcac taggaatagg ggttaaggtt atgtcaacca
    14101 gaaattcact tattaaaaat tctctttata atgttgctta tagaatgtta aatatcatat
    14161 ttccattagt atccgcaaca tatactgcac ggataatttt agctagtgga gttggggagg
    14221 tctcgtttgc acaaaatgtt gtttcttact ttacaacgat agctgctatg ggtattccaa
    14281 attatggtat acgagaaatt gctaaaacta gaaataaagc agaggctacg aataaagttt
    14341 tttcagagct atttctgatt aatggattgt ctacattact gtgttctata gtatatttaa
    14401 ttctgatttt gacattcaat agcatttttg ataatacatc aatgtatctt gctgtgggtt
    14461 taacattagt gtttaacttc cttaatatcg attggttcta tcaaggaaaa gaggactatg
    14521 catacatcac gaaacgtagt ttcagtataa aacttatttc tctttttagt ttatttattt
    14581 ttgttagaga tactgacgat gcagttaact atgcattgat ttctagctta gcaattggcg
    14641 ggaataatat ttttaatctt gttaatttaa ggaaatataa tattagattt agttttaata
    14701 atattaagat tagaagacac ttaaaaccta tttttgtttt gttgggttca gtgattgcta
    14761 ttgaaatcta tactatgctg gataccacta tgattggtgc tatggtagga acgactgagg
    14821 taggttatta tacaaattct atgaagctag ttaaattgct gataactgtg attaccgcta
    14881 ttggaggagt gcttttacca cgactaagtg attattattc taagggagaa tttgaaaaat
    14941 taaatcacat cgttgataaa gtttttagaa tcatgttgtt tcttttttta ccagcccaag
    15001 ttgcattaat tctagttgca ccagtaatta tgccgatttt atttggtgat agttttatac
    15061 cagcagtgtt aacacttcaa cttacttctt tgcttatatg tacattaggg tttagtaatt
    15121 tatttgggac tcaaatatta ctaacatttg gagatgagcg aaagcttttg attagcacaa
    15181 ttttaggagc gcttagtaat atcgctttga acctaattct gattccagta atggctcaaa
    15241 atggagcagc gttggcatct gtgattagtg aaacaattgt tactttaaca gcatactact
    15301 atgcgaaaaa acgtgtgaca attaggtttg acttaggatt ttatttgcca actgttgttt
    15361 caacaataat catgggtgga gctatatatg tagtaatgca attgtatatt ggggatatag
    15421 aaaaaatgtt attttcaact ttgttaggag gtgttgtatt ccttttaatt aacgttttta
    15481 tgaagaatcc tattatatat gaatttacag gtattataaa gagaaagaga taattatgta
    15541 cgactattta atcgttggag cgggtttgtc tggagcaatc ttcgcacacg aagctacaaa
    15601 gcgtggaaaa aaagtaaaag tgattgataa acgcgatcac attggaggga acatatactg
    15661 tgagaatgta gaaggtatca atgttcataa atatggtgcc catatcttcc atacttctaa
    15721 taaaaaagtc tgggactacg tcaatcaatt tgctgagttt aacaactata tcaactcacc
    15781 tgtcgcaaac tataagggaa gtctttataa ccttcctttc aatatgaata ccttctatgc
    15841 tatgtggggc acaaaaactc cacaagaagt gaaggataag attgctgagc agacagctgg
    15901 tatgaaggat gttgagccga aaaatctgga agaacaagct atcaagttga ttggtccgga
    15961 tatctatgaa aagttgatca agggttatac agaaaagcaa tggggacgct cagcgataga
    16021 acttcctcca tttatcataa aacgccttcc agttcgttta acctttgata ataactattt
    16081 taatgaccgt taccaaggga ttcctattgg tggttacaat gtcatcatcg aaaatatgct
    16141 gaaagatgta gaagttgaac ttggagtaga cttttttgct catcgtgaag agttggaagc
    16201 atctgctaac aaagttgtct tcacaggaat gatcgaccaa tattttgact acaagcacgg
    16261 agagttagaa taccgtagcc ttcgttttga gcatgagatt ttagacgagg aaaattatca
    16321 agggaatgct gtagtgaact atacagagcg tgagatccct tatactcgta tcatcgaaca
    16381 caaacatttt gaatatggaa tgcagccaaa gacagttatc acgcatgaat atccagctga
    16441 ctggaagcgt ggggacgagc cctactatcc tattaacgat gagaaaaata atgctatgtt
    16501 tgctaaatac caagaagaag cagcgcagaa tgataaagtt atcttttgtg ggcgtttagc
    16561 agattataag tattacgata tgcatgtggt gattgaacgg gcgcttgagg ttgtggagaa
    16621 agaatttagt aattgaaaaa caacgaagaa aggttgctta ttatgaaagg tattattcta
    16681 gcaggtggtt cgggaactcg cttgtatcct ttgactcgag ccgcatcaaa acaacttatg
    16741 ccggtttatg ataaaccgat gatttactac ccactttcaa cattaatgtt ggctgggatt
    16801 agggatattt tgattatctc aactcctcaa gatttgcctc gttttaaaga gcttcttcaa
    16861 gatggttccg agtttggtat taaactttct tatgctgagc aaccaagtcc agatggtttg
    16921 gcacaagcct ttatcattgg ggaagagttt atttctgatg atagcgttgc gctaatctta
    16981 ggtgataata tctaccatgg ttctgggctt tccaagatgc tacaaaaggc agcgagtaag
    17041 gagtcgggag caactgtttt tggctaccat gtcaaggatc cagagcgctt tggtgtggtt
    17101 gagtttgatc aggatatgaa ggctatttct attgaagaaa agccagagca acctcgttca
    17161 aactatgcag ttacaggtct ctatttctat gataatgatg tagtagagat tgccaagagt
    17221 attaaaccaa gtcctcgtgg tgaactggaa attacagatg taaacaaagc ttacctagat
    17281 cgtggtgatt tgtctgttga gcttatggga cgtggctttg cttggctgga tactggaact
    17341 catgaaagtt tactagaggc ttcacagtac atcgaaacag tccaacggat gcaaaatgtt
    17401 caggtagcaa acttagaaga aattgcctat cgcatgggtt atatcagtcg tgaagatgta
    17461 ttgaccttag ctcaaccact taagaaaaat gaatacggac agtatctgct ccgtttgatt
    17521 ggagaagcat agatgacaga taattttttc ggtaagacgc ttgcggcacg caaggttgaa
    17581 gctattccag gcatgttgga gtttgatatc cccgttcatg gagataatcg tggctggttt
    17641 aaagaaaatt tccaaaagga aaaaatgctt ccacttggat ttccagagtc tttctttgca
    17701 gaaggaaaat tgcaaaacaa tgtatccttc tcacgtaaaa atgtccttcg agggctccac
    17761 gcagagcctt gggataagta catctctgta gcagatggag ggaaagttct gggttcttgg
    17821 gttgatctac gcgagggtga aacctttggg aatacctatc agacagtaat tgatgcaagc
    17881 aagggaatct ttgttcctcg aggcgtagct aatggcttcc aagttctatc agatacagtg
    17941 tcatatagct atctggtcaa tgattactgg gctctcgagc tcaaacccaa gtatgccttt
    18001 gtgaactacg ctgatccaag ccttggtatt gaatgggaaa atattgcaga agcagaggtt
    18061 tcagaagcag ataaacatca tcccctactt aaggatgtaa aacctttgaa aaaagaagat
    18121 ttgtaaaaag gaaagaatat gactgaatac aaaaatatta tcgtgacagg tggagctggc
    18181 tttattggtt ctaactttgt ccattatgtt tacgagaact ttccaggtgt tcacgtgaca
    18241 gtcctagata agttgactta tgctggaaat cgcgcgaata ttgaggaaat tttaggtaat
    18301 cgtgttgagt tagttgttgg tgacattgct gatgcggagt tggtagacaa gttggctgct
    18361 caagcagatg ctatcgttca ttatgcagcg gaaagccaca atgataattc gctcaatgat
    18421 ccatcgccat ttattcatac taacttcatc ggaacctata ctcttttaga agctgctcgt
    18481 aagtatgata ttcgcttcca ccatgtatcg acagatgaag tttatgggga tctcccttta
    18541 cgcgaagatt tgccaggtca tggtgaagga ccaggtgaga aatttactgc tgaaacaaaa
    18601 tacaacccaa gctctccgta ctcatcaacc aaggcagcct cagatttgat tgtcaaagcc
    18661 tgggtgcgtt cttttggagt caaggcaacg atttccaact gttcaaataa ctacggtcct
    18721 tatcaacata tcgaaaaatt catcccacgt cagattacta acatcctaag tggaattaag
    18781 ccaaaacttt acggtgaagg taagaatgtt cgtgactgga ttcataccaa tgaccattct
    18841 tcaggagttt ggacaatctt gacaaaaggg caaatcggtg aaacctactt gattggggct
    18901 gatggtgaga agaacaataa ggaagttttg gaacttatcc ttaaggaaat gggacaagct
    18961 acggatgcct atgatcatgt gactgaccgt gcaggacatg accttcgcta tgcgattgat
    19021 gccagcaagc tccgtgatga gttggggtgg aaacctgaat ttaccaactt tgaagctggg
    19081 ctcaaggcaa caatcaagtg gtatacagat aaccaagaat ggtggaaagc agaaaaagaa
    19141 gctgttgaag ccaattatgc taagactcag gagattatta cagtataaaa agcaggaaat
    19201 agctgctttt tattgctata ttgggaagag ttacatatta gaaaggtcta gagatgattt
    19261 taattacagg ggcaaatggc caattaggaa cggaacttcg ctatttattg gatgaacgta
    19321 atgaagaata cgtggcagta gatgtggctg agatggacat taccaatgaa gaaatggttg
    19381 agaaagtttt tgaagaggtg aaaccgactt tagtctacca ttgtgcagcc tacaccgctg
    19441 ttgatgcagc agaggatgaa ggaaaagagt tggacttcgc catcaatgtg acggggacaa
    19501 aaaatgtcgc aaaagcatct gaaaagcatg gtgcaactct agtttatatt tctacggact
    19561 atgtctttga cggtaagaaa ccagttggac aagagtggga agttgatgac cgaccagatc
    19621 cacagacaga atatggacgc actaagcgta tgggggaaga gttagttgag aagcatgtgt
    19681 ctaatttcta tattatccgt actgcctggg tatttggaaa ttatggcaaa aacttcgttt
    19741 ttaccatgca aaatcttgcg aaaactcata agactttaac agttgtaaat gaccagtacg
    19801 gtcgtccgac ttggactcgt accttggctg agttcatgac ctacctagct gaaaatcgta
    19861 aggaatttgg ttattatcat ttgtcaaatg atgcgacaga agacacaaca tggtatgatt
    19921 ttgcagttga aattttgaaa gatacagatg tcgaagtcaa gccagtagat tccagtcaat
    19981 ttccagccaa agctaaacgt ccgctaaact caacgatgag cctggccaaa gccaaagcta
    20041 ctggatttgt tattccaact tggcaagatg cattgcaaga attttacaaa caagaagtga
    20101 gataagtagt agaatgattt tctagtctaa taaaagaggc agataatgaa ctccaaagga
    20161 gcttaagatg tacgattatc ttgttgttgg tgctgatctc tttggcgcat agctttggct
    20221 cagtttctat tatcgctcac accatccatc agaagtttaa tctgaaggta cccaattatc
    20281 gccaagaaga agattgggct aggatgggtt taccaatcac acgtaaggaa atctctaatt
    20341 ggcatatcaa ggcaagtcaa tactatttag agtcccttta taacctttta cgagaaaagt
    20401 tgttagaaca acctcttctt catgcggatg aaacctctta tcgggtgcta gagagtgata
    20461 gccatctgac ctactattgg acctttttgt ctgggaaagc tgagaatcaa gcaatcacgc
    20521 tgtaccatca tgatcagcgt cggagtggtt tagtagtaca agaattccta ggagattatt
    20581 ctggctatgt gcattgtgat atgttgcggc agtaacttag gactttagtc ctctagttct
    20641 gcctatgcga tagcagtcca aggtttagga gcaaggcgac gctaagcttg gtaaactaag
    20701 cttagcgtca actggaagaa gctgaacttg ttggatgttg ggcacatgtg agaaggaagt
    20761 tttttgaagc gacccccaag caagcagata aatcatcctt aggagctaaa ggtttagctt
    20821 attgtgatca gttattttcc ctggaaagag actgggaggc tttgccagct gatgaacgac
    20881 tacagaaacg tcaagaacat ctccagccct taatggaaga cttctttgct tagtgccggc
    20941 gtcagtcagt tttagcaggt tcaaaactag gaagggcaat tgaatacagc ctcaagtatg
    21001 aagaaacctt taagactatt ttgaaagacg gacatctggt cctttccaat aatctagctg
    21061 aacgcgccat taaatcattg gttatgggac ggagtaaaag aattcagtgg actcttttag
    21121 cctaagctaa attttaaaaa gcgagggtgg ttattttctc aaagttttga aggagctaaa
    21181 gcaacagcta ttattatgag tttgttggaa acagctaaac gtcatcaatt aaatagcgag
    21241 aaatatctat tctatcttct agaatgtctt ccaaacgagg aaactctcgt aaacaaagag
    21301 gttttagagg cttatttacc atggactaaa gttgtacaag aaaagtgcaa ataagaaatc
    21361 tccagattag gaactatccg tgagttctct agtctggaga tttttcaata tacttcgtta
    21421 ttggacggtt acgatattca tattttttgc aaagatgttg tttgaaaaat aattttcaaa
    21481 aattctgaaa attctgttga caactttctg aaaagagtct ataatggaga gaaagtttta
    21541 aaggagaaaa tgatgaaaag ttcaaaacta tttgcccttg cgggcgtgac attattggcg
    21601 gcgactactt tagctgcatg ctctggatca ggttcaagca ctaaaggtga gaagacattc
    21661 tcatacattt atgagacaga ccctgataac ctcaactatt tgacaactgc taaggctgcg
    21721 acagcaaata ttaccagtaa cgtggttgat ggtttgctag aaaatgatcg ctacgggaac
    21781 tttgtgccgt ctatggctga ggattggtct gtatccaagg atggattgac ttacacttat
    21841 actatccgta aggatgcaaa atggtatact tctgaaggtg aagaatacgc ggcagtcaaa
    21901 gctcaagact ttgtaacagg attaaaatat gctgctgata aaaaatcaga tgctctttac
    21961 cttgttcaag aatcaatcaa agggttggat gcctatgtaa aaggggaaat caaagatttc
    22021 tcacaagtag gaattaaggc tctggatgaa cagacagttc agtacacttt gaacaaacca
    22081 gaaagcttct ggaattctaa gacaaccatg ggtgtgcttg cgccagttaa tgaagagttt
    22141 ttgaattcaa aaggagatga ttttgccaaa gctacggatc caagtagtct cttgtataac
    22201 ggtccttatt tgttgaaatc cattgtgacc aaatcctctg ttgaatttgc gaaaaatccg
    22261 aactactggg ataaggacaa tgtgcatgtt gacaaagtta aattgtcatt ctgggatggt
    22321 caagatacca gcaaacctgc agaaaacttt aaagatggta gccttacagc agctcgtctc
    22381 tatccaacaa gtgcaagttt cgcagaactt gagaagagta tgaaggacaa tattgtctat
    22441 actcaacaag actctattac gtatctagtt ggtacaaata ttgaccgtca gtcctataaa
    22501 tacacatcta agaccagcga cgaacaaaag gcatcgacta aaaaggctct cttaaacaag
    22561 gatttccgtc aggctattgc ctttggattt gaccgtacag cctatgcctc tcagttgaat
    22621 ggacaaactg gagcaagtaa aatcttgcgt aatctctttg tcccaccaac atttgttcaa
    22681 gcagatggta aaaactttgg cgatatggtc aaagagaaat tggtcactta tggggatgaa
    22741 tggaaggatg ttaatcttgc agattctcag gatggtcttt acaatccaga aaaagccaag
    22801 gctgaatttg ctaaagctaa atcagcctta caagcagaag gagtccaatt cccaattcat
    22861 ttggatatgc cagttgacca aacagcaact acaaaagttc agcgcgtcca atctatgaaa
    22921 caatccttgg aagcaacttt aggagctgat aatgtcatta ttgatattca acaactacaa
    22981 aaagacgaag taaacaatat tacatatttt gctgaaaatg ctgctggcga agactgggat
    23041 ttatcagata atgtcggttg gggtccagac tttgccgatc catcaaccta ccttgatatt
    23101 atcaaacctt ctgtaggaga aagtactaaa acatatttag ggtttgactc aggggaagat
    23161 aatgtagctg ctaaaaaagt aggtctatat gactacgaaa aattggttac tgaggctggt
    23221 gatgagacta cagatgttgc taaacgctat gataaatacg ctgcagccca agcttggttg
    23281 acagatagtg ctttgattat tccaactaca tctcgtacag ggcgtccaat cttgtctaag
    23341 atggtaccat ttacaatacc atttgcattg tcaggaaata aaggtacaag tgaaccagtc
    23401 ttgtataaat acttggaact tcaagacaag gcagtcactg tagatgaata ccaaaaagct
    23461 caggaaaaat ggatgaaaga aaaagaagag tctaataaaa aggctcaaga agatctcgca
    23521 aaacatgtga aataactgtt gcaaaatata agaaaggatt tagtatttcc cttgaatgct
    23581 gaatcctttt ttacatttgt aaagaaagat tctaaaatgt acggaccccc aaaagttgga
    23641 gcctcttttt gtcagaatag agaaaatttt tgttaatttt acttgtttcc tattgctttc
    23701 tcagctatta tttgttatat taaaagtata attatttttt atttatcaga gttaagcatt
    23761 gcactttcag aggaaggagt attttttaaa aagaaaatgt aaacgcttgc tcaaaaatga
    23821 aaggatttag aagtttatga ataaaggatt atttgaaaaa cgttgtaaat atagtattcg
    23881 gaaattttca ttaggtgttg cttctgttat gattggagct gcattctttg ggacaagtcc
    23941 ggttcttgca gatagcgtgc agtctggttc cacggcgaac ttaccagctg atttagctac
    24001 tgctcttgca acagcaaaag agaatgatgg gcgtgatttt gaagcgccta aggtgggaga
    24061 agaccaaggt tctccagaag ttacagatgg acctaagaca gaagaagaac tattagcact
    24121 tgaaaaagaa aaaccggctg aagaaaaacc aaaagaggat aaacctgcag ctgctaaacc
    24181 tgaaacacct aagacggtaa cccctgaatg gcaaacggta gcgaataaag agcaacaagg
    24241 aacagtcact atccgagaag aaaaaggtgt ccgctacaac caactatcct caactgctca
    24301 aaatgataac gcaggcaaac cagccctgtt tgaaaagaag ggcttgaccg ttgatgccaa
    24361 tggaaatgca actgttgatt taaccttcaa agatgattct gaaaagggca aatcacgctt
    24421 tggtgtcttt ttgaaattta aagataccaa gaataatgtt tttgtcggtt atgacaagga
    24481 tggctggttc tgggagtata aatctccaac aactagcact tggtatagag gtagtcgtgt
    24541 tgctgctcct gaaacaggat caacaaaccg tctctctatc actctcaagt cagacggtca
    24601 gctaaatgcc agcaataatg atgtcaatct ctttgacaca gtgactctac cagctgcggt
    24661 caatgaccat cttaaaaatg agaagaagat tcttctcaag gcgggctctt atgacgatga
    24721 gcgaacagtt gttagcgtta aaacggataa ccaagagggg gtaaaaacag aggatacccc
    24781 tgctgaaaaa gaaacaggtc ctgaagttga tgatagcaag gtgacttatg acacgattca
    24841 gtctaaggtc ctcaaagcag tgattgacca agccttccct cgtgtcaagg aatacagctt
    24901 gaacgggcat actttgccag gacaggtgca acagttcaac caagtcttta tcaataacca
    24961 ccgaatcacc cctgaagtca cttataagaa aatcaatgag acaacagcag agtacttgat
    25021 gaagcttcgc gatgatgctc acttaatcaa tgcggaaatg acagtacgct tgcaagttgt
    25081 agacaatcaa ttgcactttg atgtgactaa gattgtcaac cacaatcaag tcactccagg
    25141 tcaaaagatt gatgacgaaa gcaaactact ttcttctatt agtttcctcg gcaatgcttt
    25201 agtctctgtt tctagtaatc aaactggtgc taagtttgat ggggcaacca tgtcaaacaa
    25261 tacgcatgtc agcggagatg atcatatcga tgtaaccaat ccaatgaagg atttggctaa
    25321 gggttacatg tatggatttg tttctacaga taagcttgct gctggtgttt ggagtaactc
    25381 tcaaaatagc tatggtggtg gttcgaatga ctggactcgt ttgacagctt ataaagaaac
    25441 agtcggaaat gccaactatg taggaatcca cagctctgaa tggcaatggg aaaaagctta
    25501 taagggcatt gttttcccag aatacacgaa ggaacttcca agtgctaagg ttgttatcac
    25561 tgaagatgcc aatgcagaca agaaagttga ttggcaagat ggtgccattg cttatcgtag
    25621 cattatgaac aatcctcaag gttgggaaaa agttaaggat atcacagctt accgtatcgc
    25681 gatgaacttt ggttctcaag cacaaaaccc attccttatg accttggatg gtatcaagaa
    25741 aatcaatctc catacagatg gtcttgggca aggtgttctc cttaaaggat atggtagcga
    25801 aggccatgac tctggtcact tgaactatgc tgatattggt aagcgtatcg gtggtgtcga
    25861 agacttcaag accctaattg agaaggctaa gaaatatgga gctcatctag gtatccacgt
    25921 taacgcttca gaaacttatc ctgagtctaa atacttcaat gaaaaaattc tccgtaagaa
    25981 tccagatgga agctatagct atggttggaa ctggctagat caaggtatca acattgatgc
    26041 tgcctatgac ctagctcatg gtcgtttggc acgttgggaa gatttgaaga aaaaacttgg
    26101 tgacggtctc gactttatct atgtggacgt ttggggtaat ggtcaatcag gtgataacgg
    26161 tgcctgggct acccacgttc ttgctaaaga aattaacaaa caaggctggc gctttgcgat
    26221 cgagtggggc catggtggtg agtacgactc taccttccat cactgggcag ctgacttgac
    26281 ttacggtggc tacaccaata aaggtatcaa cagtgccatc acccgcttta tccgtaacca
    26341 ccaaaaagat gcttgggttg gggactacag aagttatggt ggtgcagcca actatccact
    26401 gctaggtggc tacagcatga aagactttga aggctggcaa ggaagaagtg actacaatgg
    26461 ctatgtaacc aacttatttg cccatgatgt catgaccaag tacttccaac acttcactgt
    26521 aagtaaatgg gaaaatggta caccggtgac tatgaccgat aacggtagca cctataaatg
    26581 gactccagaa atgcgagtgg aattggtaga tgctgacaat aataaagtag ttgtaactcg
    26641 taagtcaaat gatgtcaata gtccacaata tcgcgaacgt acagtaactc tcaacggacg
    26701 tgtcatccaa gatggttcag cttacttgac tccttggaac tgggatgcaa atggtaagaa
    26761 actttctact gataaggaaa agatgtacta cttcaatacg caggccggtg caacaacttg
    26821 gacccttcca agcgattggg caaagagcaa ggtttacctt tacaagctaa ctgaccaagg
    26881 taagacagaa gagcaagaac taactgtaaa agatggtaaa attaccctag atcttctagc
    26941 aaatcaacca tacgttctct atcgttcgaa acaaaccaat cctgaaatgt catggagtga
    27001 aggcatgcac atctatgacc aaggatttaa cagtggtacc ttgaaacatt ggaccatttc
    27061 aggcgatgct tctaaggcag aaattgtcaa gtctcaaggg gcaaacgata tgcttcgtat
    27121 tcaaggaaac aaagaaaaag ttagtctcac tcagaaatta actggcttga aaccaaatac
    27181 caagtatgcc gtttatgtcg gtgtcgataa ccgtagtaat gccaaggcga gcatcactgt
    27241 aaatactggt gaaaaagaag tgactactta taccaataag tctctcgctc tcaactatgt
    27301 taaggcctac gcccacaata cacgtcgtga caatgctaca gttgacgata caagttactt
    27361 ccaaaacatg tacgccttct ttacaactgg atcggacgtc tcaaatgtta ctctgacatt
    27421 gagtcgtgaa gctggtgatc aagcaactta ctttgatgaa attcgtacct ttgaaaacaa
    27481 ttcaagcatg tacggagaca agcatgatac aggtcaagga accttcaagc aagactttga
    27541 aaatgttgct cagggtatct tcccatttgt agtgggtggt gtcgaaggtg tcgaagacaa
    27601 ccgcactcac ttgtctgaaa aacacgatcc atatacacaa cgtggttgga acggtaagaa
    27661 agttgatgat gttatcgaag gaaattggtc actcaagaca aatggactag tgagccgtcg
    27721 taacttggtt taccaaacta ttccgcaaaa cttccgtttt gaagcaggta agacctaccg
    27781 tgtaaccttt gaatacgaag caggttcaga caatacctat gcttttgtag tcggtaaggg
    27841 agaattccag tcaggtcgtc gtggtactca agcaagcaac ttggaaatgc atgaattgcc
    27901 aaatacttgg acagattcta agaaagccaa gaaggcaacc ttcctcgtga caggtgcaga
    27961 aacaggggat acttgggtag gtatctactc aactggaaat gcaagtaata ctcgtggtga
    28021 ttctggtgga aatgccaact tccgtggtta taacgacttc atgatggata atcttcaaat
    28081 cgaagaaatt accctaacag gtaagatgtt gacagaaaat gctctgaaga actacttgcc
    28141 aacggttgcc atgactaact acaccaaaga gtctatggat gctttgaaag aggcggtctt
    28201 taacctcagt caggccgatg atgatatcag tgtggaagaa gcgcgtgcag agattgccaa
    28261 gattgaagcc ttgaagaatg ctttggttca gaagaaaacg gctttggtag cagatgactt
    28321 tgaaagtttg gatgcgccag ctcaaccagg tgaaggtctt gagaatgcct ttgatggcaa
    28381 tgtgtctagt ctatggcata catcatgggg cggaggagat gtaggcaagc ctgcaaccat
    28441 ggtcttgaaa gaagcaactg aaatcactgg acttcgttat gttccacgtg gatcaggttc
    28501 aaatggtaac ttgcgtgatg tgaaacttgt tgtgacagct gagtctggca aggagcatac
    28561 ctttactgca actgattggc cagataacaa taagccaaaa gacattgatt ttggtaagac
    28621 aattaaggct aagaaaattg tccttacagg tactaagact tacggagatg gtggcgataa
    28681 ataccaatct gcagcggaac ttatctttac tcgtccacag gtagcagaaa cacctcttga
    28741 cttgtcaggc tatgaagcag ctttggctaa ggctcagaaa ttaacagaca aagacaatca
    28801 agaggaagta gctagcgttc aggcaagcat gaaatatgcg acggataacc atctcttgac
    28861 ggaaagaatg gtggaatact ttgcagatta tctcaaccaa ttaaaagatt ctgctacgaa
    28921 atcagatgct ccaactgtag agaaacctga gtttaaactt agctctttag cttccgaaca
    28981 aggtaagacg ccagattata agcaagaaat agatagacca gaaacacctg aacaaatctt
    29041 gccagcaaca ggtgagagtc aatctgacac agccctcttc ctagcaggtg ttagcctagc
    29101 cctatctgct ctctttgtag taaaaacgaa gaaagactag tatttagtaa aacctcttaa
    29161 ccagattacg gaagcagtct ctatcttttc caatgaggtt tatagtacag aaaaagcctg
    29221 agaagatgtc ttctcaggct tttgttaagc acataaatac aatagtgcta tgaaaaaatc
    29281 acccagaaaa atctgtatga taaatgttat ggttgtgctg gttgaggatt ctgattttgt
    29341 tgatcagggg ttgtatttga ttgttgcgta ttattgttag gattggtagt cgtactatta
    29401 tttgtgcttg gagtggttga gctagactgt gaagttgaac tatctgatga tgagcttgaa
    29461 ctttcagttg atgggggttg ttgtggagca ggtgagctcc acgtagaacg agcaccattt
    29521 ttaaatacga attctccatt tctgtagagc ccctctggta tattccaatc ctctggattg
    29581 cttccttcag acagataggt catcatagag cggtaaactt tggcagcgac cgtaaggcca
    29641 ttgcctacaa gtggtgtcag acggttagaa tagcctgtcc atacagccat tgaatattta
    29701 cgcgtatagc cagcaaatag ttcatcaggt gctacaaatt gagaggtctt gatgtggttt
    29761 tcaatttcct cgtctgtata gttagaggtt cctgttttac cagcctgagg gagccaagca
    29821 agataggcat ttcgtccagt tccataagtc aagactgttt tcatcatgtc ggtcatcata
    29881 taggctgttg tttccttcat ggcacgagtt ccgacattag agaactcttt ttcactccca
    29941 tcactaaaga cgactttatg gatatacatt ggtttatagt aagttccacc atttgcaaaa
    30001 gcagcgtaag cagcagccat cttttcacta cttgctccat attttttgtc tgattcggtt
    30061 gtgttacttg aaatggcatt tgagtagtga atacttgggt agtcgattcc gagaccattt
    30121 aggaaagtct tggcgcggtt gagtccgacc ttgtttagag tttccacggc tgggacgttt
    30181 cgcgattgtt gcagggcgta ttgcaaggtg atgttgccaa agtagcccct atcccagtta
    30241 taaacaggag tatttgtccc agggtagtta tagggctcat cgtgaacgat agtagcagtt
    30301 gaatcgtaga caccgtactc caaggcagga gcatagtctg tgatcggttt catagttgat
    30361 ccccagtcgc ggtttgtttc tactgcttgg ttaattccga aagaaacatt acttgactga
    30421 tggcgtgctc ctagctgggc aatgacttta ccgttagaaa catcaacaat ggtagaagcg
    30481 acttgcaatt catcgtctgg ataggcaacg tattcgtctg tattgtaaat atcccacaga
    30541 tgtttttgag cttcttggtc tacatttgtg tagacatcca tcccagttgt gagtaggtta
    30601 tagcctgttt cttcttcaac ttgattgatg acttccttga ggtaattatc catgtaagca
    30661 gggtaattac ttgctgattt gagactttgt agcccatcag taattggtgt attgactgct
    30721 ttctcatact gttcagcaga gatgtagcct tgatttttca tttcagataa gaccaagttt
    30781 cggcggtctt gggctgcttc tggatgtgaa taggggtcat attggtttgg tgcctgaggc
    30841 attccagcca gcaaggctaa ctgaggtaaa cttaaattat tgaggtcttt accatagtag
    30901 ttttgagctg ctgtctgcat tccatagttc ccattagaca tgtagacctt atttatatag
    30961 taggtcaaga tttcttgctt ggttgctttt tgttctaact gaatcgctaa ccaagcttcc
    31021 tgagccttac gagaaatagt ctggtcggaa gtcgaagttg aaaagtaagt caacttaatc
    31081 aactgttgag tgagagttga tccaccttgg agggaattgc tttgcagatt gcgcaagaaa
    31141 gctcccagga tacggatggt atcaatcccc ctgtggtcga agaagcgatg gtcttcgata
    31201 gaaacgattg ccttaaccaa atctgtggga atatcattag cttgggcatt gacgcggcgt
    31261 tcagaaccca agtcagcaat gagttgattt ttattgtcgt agattttact agaagttgtt
    31321 gcaactagtt tactctcgga taggctagga gccttgctaa cgtagtagaa aaaaactcct
    31381 ccgcctaaga caatggctgc gataaccaag cttaagaagc taatgctcag atacttgatt
    31441 aggcgcagaa tcgttggttt gttcatcttg ttttaccacc taataaatgt tctttgataa
    31501 cattgagata aggaatttga gggaaggcac cagccttgat ttcatatcca tattctcgaa
    31561 tatattcaag tggcattgat ttttgtccct tatcttgatg atagaagcga atcaaatcga
    31621 atgccggcaa taagtaggtt tcttgctgag aagaaaagtg aagaaggaca aagcagattc
    31681 cttgttgggc aaggacttgt tccatatgct gaatctgatg tggatgaaaa tttttcatcg
    31741 gaatcgcacg tttttgtttt gtttccttga cttcaaagtc gatgtaatat ccattataaa
    31801 cgccagaata gtccgtcgtt gaagcttgtc gaaaataggc ttcaacaatc ttggcacgac
    31861 ttcgttgtgg atagtccact tgtacgattt gaataggagt tggtttctta tgtataacag
    31921 ccaagccctg agacaaatag tagtcgttgg tagcattgat catcttttca aaagacattc
    31981 ctcgatttgc gaaatttttg ggttgagaaa gagatgtttg tcttttttgt gatgaaactt
    32041 tatgtggata gttgaccata attctcctta ttggtacaat aacatcactt tattatacca
    32101 taatttgcac agaaagggtt aaaaatggct acagctttgg ttttaggcta ttctgctttt
    32161 gatttgggtt tattttctga taaggatcct cgtcttaaat tgattaaaaa agcgatacgt
    32221 aaagatttag aggctatggc agcagatggg gtgtcttggc ttgtgtttac agggagtttg
    32281 gggtttgaat attgggtttt agaggttgct caggagatga aaaccgaata cggtttccag
    32341 ttggccacca tttttgcttt tgaaacccat ggggaaaatt ggaatgaagg caatcagatg
    32401 aaactgagtc gctttaagca ggtagacttt gtcaaatatg cttatcctcg ctatgaacac
    32461 aaggggcagt taagagatta ccagcagttt ttgctggaaa acacgactag ttcctatctt
    32521 ttttatgatg aagaaaatga aacgaaacta gcttattttt accaaaagat gaaaaatcaa
    32581 gaggactatt ttataaagag attaacattt gatcaattaa atgaacttgc tgaaaatttt
    32641 tccgaaaatt gaagctttga ccttgatttt tgtttgcctt tttttatata ataatactag
    32701 caagcgagaa tggagagaga catggcaagt attatttttt cagcgaaaga tatttttgaa
    32761 caagagtttg gacgtgaagt ccgtggctat aataaagtag aagttgacga gtttttagac
    32821 gatgtcatca aggactatga aacctatgct gccttggtca agtcacttcg tcaggaaatt
    32881 gcggatttga aggaagaatt aactcgtaaa ccgaaacctt caccagttca agcagaaccc
    32941 cttgaagcgg caattacaag ttctatgacg aattttgata ttttgaaacg cctgaataga
    33001 ttggaaaaag aagtttttgg taaacaaatt ttagataact cagattttta agtagttatt
    33061 tgagatgtgc aatttttgga taatcgcgtg aggagaattg cttctcatga ggaaagtcca
    33121 tgctagcaca ggctgtgatg cctgtagtgt ttgtgctagg cgaaaccata agcctaggga
    33181 cgagaaatcg ttacggcagt tgaaatggct aagtccttgg ataggccaga gtagacttga
    33241 aagtgccaca gtgacggagt ctttctggaa acagagagag tggaacgcgg taaacccctc
    33301 aagctagcaa cccaaatttt ggtcggggca tggagtacgc ggaaacgaac gtagtattct
    33361 gactgctatc agctagagct gttagtggta gacagatgat tatcgaagga agtggtccta
    33421 gtcacttctg gaacaaaaca tggcttatag aaaattgcat ataggttggg gctgagaaat
    33481 tttctcaacc tcatttttta aagtggacat atagaaaggt cttgcaagac tgtaacatga
    33541 aaaaagaatt taatttaatt gcaactgtgg cagcagggct tgaggctgtc gttggtcgtg
    33601 aagtgcgaga gttgggctac gattgtcagg ttgaaaatgg acgtgttcgt tttcaaggag
    33661 acgtgagagc tattatcgaa accaaccttt ggcttcgggc agcagatcgt atcaaaatta
    33721 tcgtaggaac gttcccagct aagacttttg aagagctatt tcagggagtt ttcgctttag
    33781 attgggaaaa ttatttacca cttggagctc ggttcccgat ttcaaaagct aaatgtgtta
    33841 agtccaaact tcacaatgag cctagtgttc aggctatttc taagaaagct gttgtcaaga
    33901 aattgcagaa acactatgct cgcccagaag gggttcctct gatggagaat ggcccagagt
    33961 ttaagattga ggtctctatt ctcaaagatg tggcaactgt catgattgat acgaccgggt
    34021 ctagcctctt taaacgtggt tatcgtaccg aaaaaggtgg cgctcctatc aaggaaaata
    34081 tggcagcagc cattttacaa ctttctaact ggtacccaga caagcctttg attgatccga
    34141 cctgtggttc ggggactttc tgtattgagg cagttatgat tgctagaaag atggcgccag
    34201 gtcttcgtcg ctcttttgca tttgaggaat ggaactggat cagcgatcgc ttgattcaag
    34261 aagtgcgcac agaagcggct aaaaaagtag aacgtgagct tgagctggat atcatgggct
    34321 gtgatattga tgctcgcatg gtggaaattg ctaaggccaa tgctcaggca gctggtgttg
    34381 caggagacat tacttttaag cagatgcgcg tgcaggattt acgttccgat aaaatcaatg
    34441 gagtaatcat ttccaatccg ccttatggtg aacgtttgtc agatgatgca ggggtgacca
    34501 agctctatgc tgagatgggg caagtatttg caccgctgaa aacttggagc aaatttatcc
    34561 tgactagtga tgaagctttt gaaagcaagt atggtagcca agcagataag aagcgtaagt
    34621 tatacaacgg aaccttgaaa gtggatttat atcaatattt tggtcagcgt gtcaaacggc
    34681 aagaggtaaa atagaaaggg atactcatga gtaaaaaaag acgaaatcgt cataaaaaag
    34741 aagctcaaga accgcaattt gattttgatg aagcaaaaga gctaacagtt ggtcaagcta
    34801 ttcgtaaaaa tgaagaagtg gaagcaggag tcttgcctga ggattccatt ttggacaagt
    34861 atgttaagca acacagagat gaaattgagg cggataagtt tgcgactcgt caatacaaaa
    34921 aagaggagtt cgttgaaact cagagtctgg atgatttaat tcaagagatg cgtgaggctg
    34981 tagagaagtc agaagcttct tcggaggaag ttccatcttc tgaagacatc ttactaccct
    35041 tgcctctgga cgatgaggag caaggcttgg atcctctatt gctagatgat gaaaatccaa
    35101 cagaaatgac tgaagaagtg gaagaggagc aaaacctttc tcgtctggat caagaggact
    35161 cagaaaagaa aagtaaaaaa ggctttattt tgaccgtttt ggcgcttgta tcagtaatta
    35221 tttgtgtcag tgcttattat gtctatcgtc aagtggctcg ttcgaccaag gaaattgaaa
    35281 cttctcaatc aactacagcc aatcaatcgg atgtggatga ttttaataca ctttatgacg
    35341 ccttttacac aaatagcaat aaaacggctt tgaaaaatag ccagtttgat aaactgagtc
    35401 aactcaagac tttacttgat aagctggaag gtagtcgtga acatacgctt gccaaatcta
    35461 aatatgatag tctagtaacg caaatcaagg ccattcaaga tgtcaatgca caatttgaaa
    35521 aaccagctat tgtggatggt gtgttggata ccaatgccaa agccaaatcg gatgctaaat
    35581 ttacggatat taaaactgga aatacggagc ttgataaagt gctagataag gctatcagtc
    35641 ttggtaagag ccagcaaaca agtacttcta gctcaagttc aagtcaaact agcagctcaa
    35701 gttcaagtca agcaagttca aatacgacta gtgagccaaa accaagtagt tcaaatgaga
    35761 ctagaagtag tcgcagtgaa gtcaatatgg gtctctcgag tgcaggggtt gctgttcaaa
    35821 gaagtgccag tcgtgttgcc tataatcagt ctgctattga tgatagtaat aactctgcct
    35881 gggattttgc ggatggtgtt ttggaacaaa ttctagcaac ttcacgttca cgtggctata
    35941 tcactggaga ccaatatatc cttgaacgtg tcaatatcgt taacggcaat ggttattaca
    36001 acctctataa gccagatgga acctatctct ttacccttaa ctgtaagaca ggctactttg
    36061 tcggaaatgg cgctggtcat gcggatgact tggactacta agcagtcgtt acaaaattct
    36121 ttcttttcaa aagtaaaaat gataaaataa aacaaatgaa acaagaggag tgtcaaatga
    36181 caaaagctaa ctttggtgtc gtaggtatgg ccgtaatggg tcgtaacctt gcccttaata
    36241 ttgaatcacg tggttacaca gttgctatct acaaccgtag taaagaaaaa acggaagatg
    36301 tgattgcttg ccatcctgaa aagaattttg taccaagcta tgacgttgaa agttttgtaa
    36361 actcaatcga aaaacctcgt cgtatcatgc tgatggttca agctggacct ggtacagatg
    36421 ctactatcca agcccttctt ccacaccttg acaaaggtga tatcttgatt gacggaggaa
    36481 acactttcta caaagatacc atccgtcgta atgaagaatt ggcaaactca ggtatcaact
    36541 ttatcggtac tggagtttct ggtggtgaaa aaggtgccct tgaaggtcct tctatcatgc
    36601 ctggtggaca aaaagaggcc tacgaattgg tttcggatgt tcttgaagaa atctcagcta
    36661 aagcaccaga agatggcaaa ccatgtgtga cttatatcgg tcctgatgga gctggtcact
    36721 atgtgaaaat ggttcacaac ggtatcgagt acggtgatat gcaattgatc gcagaaagct
    36781 atgacttgat gcaacacttg ctaggccttt ctgcagagga tatggctgaa atctttactg
    36841 agtggaacaa gggtgaattg gatagctact tgatcgaaat cacagctgat atcttgagcc
    36901 gtaaagacga tgaagaccaa gatggaccaa tcgtagacta catccttgat gctgcaggta
    36961 acaagggaac tggtaaatgg acgagccaat catctcttga ccttggtgta ccattgtcac
    37021 tgattactga gtcagtgttt gcacgctaca tttcaactta caaagaagaa cgtgtacatg
    37081 ctagcaaggt gcttccaaaa ccagctgcct tcaactttga aggagacaag gctgaattga
    37141 ttgaaaaaat ccgtcaagcc ctttacttct caaaaatcat ttcatacgca caaggatttg
    37201 ctcaattgcg tgtagcctct aaagaaaaca actggaactt gccatttgca gatatcgcat
    37261 ctatctggcg tgatggctgt atcatccgtt ctcgtttctt gcaaaagatt acagatgctt
    37321 acaaccgcga tgcagatctt gccaaccttc ttttggacga gtacttcttg gatgttactg
    37381 ctaagtacca acaagcagta cgtgatatcg tagctcttgc ggttcaagca ggtgtgccag
    37441 tgccaacttt ctcagcagct attacttact ttgatagcta ccgttcagct gaccttccag
    37501 ctaacttgat ccaagcacaa cgtgactact ttggtgctca cacttaccaa cgtaaagaca
    37561 aagaaggaac cttccactac tcttggtatg acgaaaaata agtaggtcag ccatggggaa
    37621 acggatttta ttacttgaga aagaacgaaa tctagctcat tttttaagtt tggaactcca
    37681 gaaagagcag tatcgggttg atctggtaga ggaggggcaa aaagcccttt ccatggctct
    37741 tcagacagac tatgatttga ttttattgaa tgttaatctg ggagatatga tggctcagga
    37801 ttttgcagaa aaattgagtc gaactaaacc tgcctcagtc atcatgattt tagatcattg
    37861 ggaagacttg caagaagagc tgaaagttgt tcagcgtttt gcagtttcat acatctataa
    37921 gccagtcttt atcgaaaatc tggtagcgcg tatttcggcg atcttccgag gtcgggactt
    37981 cattgatcaa cactgcagtc tgatgaaagt tccaaggacc taccgcaatc ttaggataga
    38041 tgttgaacat cacacggttt atcgtggtga agagatgatt gctctgaccc gccgtgagta
    38101 tgaccttttg gcgacactta tgggaagtaa gaaagtattg actcgtgagc aattgttgga
    38161 aagtgtttgg aagtatgaaa gtgcgaccga gacaaatatc gtagatgtct atatccgcta
    38221 tctacggagc aagcttgatg ttaaaggcca aaaaagctac attaaaaccg tgcgtggtgt
    38281 tggttacacc atgcaagaat agaaaagcag ttgcagttgt gtaactgctt ttttgaggag
    38341 tttttatata ttgacataca atctagtttt tactacaatc gttttaggag gatatataaa
    38401 atgaagcttt tgaaaaaaat gatgccaatc gcattagcag tctttttctt tggtttgcta
    38461 gcgacaagta cagtatttgc agatactatg ggtggccgat ttgttgataa ggataataga
    38521 aaatattatg taaaagatga tcataaagca atctattggc ataaaataga cggtaaaact
    38581 tactattttg gtgatattgg agagatggtt gtcggttggc aatacttaga aattcatgga
    38641 acaggttatc gtgatgattt atttgataat cgtccagtct tcgaaattgg ccttcaggag
    38701 aagtggtact attttggaca agatggtgct ttgctagaac aaacagataa acaagtacta
    38761 gaggcaaaaa cgtctgaaaa tacaggaaaa gtatacggtg aacaatatcc tctatctgct
    38821 gaaaagaaaa cttattattt tgataataat tatgctgtaa agacaggctg gatttatgaa
    38881 gacggcaatt ggtattattt aaataagcta ggaaattttg gcgatgattc ttacaatcca
    38941 ctaccaattg gtgaagttgc taagggttgg actcaagatt ttcatgttac tattgacatt
    39001 gatagaagca aacctgctcc atggtactac ctagatccag caactggcat catgcaaact
    39061 ggttggcaat ttctaggtaa tagatggtac tacctccgtt catcaggagc aatggcaact
    39121 ggttggtatc aagatggttc aacttggtac tatttagatc cttctaatgg agatatgaaa
    39181 ataggttgga caaaagtaaa tggaaactgg tattatctca attcctctgg agcaatggtt
    39241 acaggtagcc aaactatcga tggtaaagtt tataatttcg cctcatctgg tgagtggatt
    39301 taatattgga gggtatatag atgaaaattt tgaaaaaaac tatgcaagtt ggactgacag
    39361 tatttttctt tggtttgcta gggaccagta cagtatttgc agatgattct gaaggatggc
    39421 agtttgtcca agaaaacgga agaacctact acaaaaaggg ggacctcaaa gaaacctact
    39481 ggcgagtgat tgatggtaag tactattatt ttgattctct atctggagag atggttgtcg
    39541 gctggcaata tatcccgttt ccatctaaag gtagtacaat tggtccttac ccaaatggta
    39601 tcagattaga aggttttcca aagtcagagt ggtactactt cgataaaaat ggagtgctac
    39661 aagagtttgt tggttggaaa acattagaga ttaaaactaa agacagtgtt ggaagaaagt
    39721 acggggaaaa acgtgaagat tcagaagata aagaagagaa gcgttattat acgaactatt
    39781 actttaatca aaatcattct ttagagacag gttggcttta tgatcagtct aactggtatt
    39841 atctagctaa gacggaaatt aatggagaaa actaccttgg tggtgaaaga cgtgcggggt
    39901 ggataaacga tgattcgact tggtactatt tagatccaac aactggtatt atgcaaacag
    39961 gttggcaata tctaggtaat aactggtact acctccgttc ctcaggagca atggccactg
    40021 gctggtatca ggaaggtacc acttggtatt atttagacca gccaaatggc gatatgaaaa
    40081 caggttggca aaaccttggg aacaaatggt actatctccg ttcctcagga gctatggcaa
    40141 ctggttggta tcaagatggt tcaacttggt actacctaaa tgcaggtaat ggagatatga
    40201 agacaggttg gttccaggtc aatggcaaat ggtattatgc ctatggttca ggtgctttgg
    40261 cagtgaatac gaccgtagac ggctattctg tcaattataa tggcgactgg gttcggtaat
    40321 gacagggtgc ttataattat attagaacac tcgcttaatc aaagaagtga ctttgttgta
    40381 cttgacctga cgattgggga gattaaaaag catgtgaaat ctacacatgc ttttttgtta
    40441 gttatgagtg ttgaacttga ctaaccattg acaaaagata agagcaatca aaataagata
    40501 caaaaatatc aatgctaact gcaccgaaac gcccgatgct atggataggg ctaataggga
    40561 gagcagggac ggggcgagaa tgtccactgt gctcagagca gagcccaccg tccccatctt
    40621 gtcactgggg atataggcaa agacagctgc ttgtaggcga gggctgagaa tgcctataat
    40681 cgtagaactg atgaaactgg tcatgaaaat tacgatatag gcttgataaa ggatactagt
    40741 tattagagcc aatagggaaa tctcacagaa aaccaagagg tgcgtgaaac ggatattttt
    40801 aaatagatta ctgctggtca tattgccaag gatagctcca caagacatga tgatggagag
    40861 cagggcgagg agttgcccaa tgcttagttg tgctagtgtt tgttggatga agcggagggc
    40921 aatcagccga ggggacacat ccaagatggc aatcatactg gtcgtcagaa acagtagtat
    40981 gacggtatct tttaacctca ggagcacagc cagcgattgt ttaagatgtt gaaaatattt
    41041 cttaaaactc agtgctgtat gtgacatttc aattcttttt tcaacctcat acaaggtatg
    41101 tcgaataaca tacaggccca aaaaggcaat gacaaaagtc agagtgttga taagggaaat
    41161 agtttgaata cttataacat tgataaggaa tgcgccagcc agattggcga caatgcggac
    41221 aaccctcatc agagactgcc tgaaccccat ggcatcatgc aggtcgtcct taattacact
    41281 gatgtagagg gcgttcatca tgtaggcaga caggtagctc aaggtgtcag agatgaggtt
    41341 gatgatgaca atcataatga ctgaaactaa tgaaaagggc gacaagacga gaaatactgt
    41401 caaaatagcg tagagcagga ttttgatttt ggcaatccag agtgcgtgtt tgactctatt
    41461 ttcttgaaaa tctcctagaa ttccgagaaa gagttgcgat agtaggggaa ccacctctga
    41521 aatggaaatc agtaaaatcg ctagcggagc gaaattgtac tgagccacat aattgataat
    41581 ggcgaggtag aaaatactgt cgccgaatga tgaaaaacag ctgtttagca gcaactgtct
    41641 atatatgttg tttgtccaaa ataatttcat acatttctcc ttatgtttgc acatcgaatg
    41701 ggaatttatt atttagtaga caccaatata ccccctgctt cctattccga agtcaaacaa
    41761 atctgcttta ccactatctc cttgaaacat cagtaaaccg tgatcatctc gttcagaaca
    41821 tgctaaaatt acctgttgga tttttttcat cagtaatttg ttttgattgt agacagtggt
    41881 ttgtagtaag ctagttattc cgtggcaata tcctgtcatc atttttagat gatggttaaa
    41941 aacaaattct tgatatttac taataatatc tttgtttccg tcacaatcgt acatacaaag
    42001 atataagatt attccggaaa ttccttcgca ccaagaaagt tgtaaatttc ctaaattttc
    42061 agtattagaa gtaacttttt ctaataattt ttttaattca gtatggaatg tatggagatc
    42121 attatagaac atagaaggtt ctaagacttt agaataggca aataaagcat atgcaattcc
    42181 acaatatcca tgagcaaagc tatagtctaa aatgctttct ttggctgtat ctctttgtag
    42241 gaaataatga taaatttccc catatactat tgtggatgaa agttttaaga gtattgtcat
    42301 tggtaaattg atagtatttt attaatgata ataggacatc agattttccc aatgcaaagt
    42361 ctatttcctc tagagtatca taattctcta ttaatttctt agaggtgacg tttgctaatt
    42421 gtagatagta ttgattttta ctgatagaaa ataaatgtag gagtaactat agatagcctg
    42481 catcaccaaa tagcagtgag tattgatatt catatgtgtg tgtcgttcta attgtcactg
    42541 ccttcttgat gatagagagt attttagaat ccagttctgg ggggtacaat ttatttagag
    42601 gaaacagtag tccagctatt cagtgttgga atgataaatt acttacgaaa tttccaaatt
    42661 ctgttgaaga agtgatcctt ccttcagaat ttacagtttt atctagtaaa aatcgtagaa
    42721 cactgttaca ttctgttttg taatcatatt tatgttcctc tattttttta attttgacta
    42781 aattatttgt ttgacttaaa tttagtagat attgtaacca aaatagttgc tcatttgtga
    42841 gctgaccttg agtatgtgat agttctagta attgaatagg atcctttagg tagattcaat
    42901 caatctataa cacaacaaca taataacact tttaggataa cttgtcgata ttatagtaaa
    42961 atgaaataat aacaggacaa atcgatcagg acagtcaaat cgatttctaa aaatgtttta
    43021 gaagtagagg tgtactattc tagtttcaat ctactatagt atatattttt acatcttgaa
    43081 ttgtcaaatt aagtgcataa ctttcccgta gcatacttca taaggcgttt tccacttaag
    43141 aaattttcgt ggtcgattat ttagaacctg tattcacaaa aaaatgttaa actagagtta
    43201 tgacacgcaa agcatatgat actgatttaa acgatcaaga atgggctaag attgaaccct
    43261 atttctccaa acaccgcacc tataaatggc cgaaacgagt acttgttaat gagactttgt
    43321 acgtcactaa aacaggttgt caatggcgca tgatccctca cgactttcct ctttacttaa
    43381 cggtatggag tttctttcgt cgttctatga cgacaggttg gttccaggtc aatggcagat
    43441 ggtactacgc ttatagctca ggtgccttgg cagtgaatac gaccgtagat ggctattctg
    43501 tcaactataa tggcgaatgg gttcaataat gaaagaagcg attgtgaatg gaaacaatcg
    43561 ctttttttgt gaaaatataa taaaatagat aggaaagaat taatacttgt atgaaaaata
    43621 agacgttttt tcgtctagta aaaggaaaaa atgacaaaaa aagttggtgt cggtcaggca
    43681 catagtaaga taattttaat aggggaacat gcggtcgttt acggttatcc tgccatttcc
    43741 ctgcctcttt tggaggtgga ggtgacctgt aaggtagttc ctgcagagag tccttggcgc
    43801 ctttatgagg aggatacctt gtccatggcg gtttatgcct cactggagta tttggatatc
    43861 acagaagcct gcattcgttg tgagattgac tcggctatcc ctgagaaacg ggggatgggt
    43921 tcgtcagcgg ctatcagcat agcggccatt cgtgcggtat ttgactacta tcaggctgat
    43981 ctgcctcatg atgtactaga aatcttggtc aatcgagctg aaatgattgc ccatatgaat
    44041 cctagtggtt tggatgctaa gacctgtctc agtgaccaac ctattcgctt tatcaagaac
    44101 gtaggattta cagaacttga gatggattta tccgcctatt tggtgattgc cgatacgggt
    44161 gtttatggtc atactcgtga agccatccaa gtggttcaaa ataagggcaa ggatgcccta
    44221 ccgtttttgc atgccttggg agaattaacc cagcaagcag aagttgcgat ttcacaaaaa
    44281 gatgctgaag gactgggaca aatcctcagt caagcgcatt tacatttaaa agaaattgga
    44341 gtcagtagcc ctgaggcaga ctttttggtt gaaacgactc ttagccatgg tgctctgggt
    44401 gccaagatga gcggtggtgg gctaggaggt tgtatcatag ccttggtaac caatttgaca
    44461 cacgcacaag aactagcaga aagattagaa gagaaaggag ctgttcagac atggatagag
    44521 agcctgtaac agtacgttcc tacgcaaata ttgctattat caaatattgg ggaaagaaaa
    44581 aagaaaaaga gatggtgcct gctaccagca gtatttctct aactttggaa aatatgtata
    44641 cagagacgac cttgtcgcct ttaccagcca atgtaacagc tgacgaattt tacatcaatg
    44701 gtcagctaca aaatgaggtc gagcatgcca agatgagtaa gattattgac cgttatcgtc
    44761 cagctggtga gggctttgtc cgtatcgata ctcaaaacaa tatgcctacg gcagcgggcc
    44821 tgtcctcaag ttctagtggt ttgtccgccc tggtcaaggc ttgtaatgct tatttcaagc
    44881 ttggattgga tagaagtcag ttagcgcagg aagccaagtt tgcctcaggc tcttcttctc
    44941 ggagttttta tggaccacta ggagcctggg ataaggatag tggagaaatt taccctgtag
    45001 agacagactt gaaactagct atgattatgt tggtgctaga ggacaagaaa aaaccaatct
    45061 ctagccgtga tgggatgaaa ctttgtgtgg aaacctcgac gacttttgac gactgggttc
    45121 gtcagtctga gaaggactat caggatatgc tgatttatct caaggaaaat gattttgcca
    45181 agattggaga attaacggag aaaaatgccc tggctatgca tgctacgaca aagactgcta
    45241 gtccagcctt ttcttatctg acggatgcct cttatgaggc tatggacttt gttcgccagc
    45301 ttcgtgagaa aggagaggcc tgctacttta ccatggatgc tggtcccaat gttaaggtct
    45361 tctgtcagga gaaagacttg gagcatttat cagaaatttt cggtcagcgt tatcgcttga
    45421 ttgtgtcaaa aacaaaggat ttgagtcaag atgattgctg ttaaaacttg cggaaaactc
    45481 tatttggcag gtgaatatgc tattttagag ccagggcagt tagctttgat aaaggatatt
    45541 cccatctata tgagggctga tattgctttt tctgacagct accgtatcta ttcagatatg
    45601 tttgatttcg cagtggactt aaggcccaat cctgactaca gcttgattca agaaacgatt
    45661 gctttgatgg gagacttctt cgctgttcgc ggtcagaatt taagaccttt ttccctagaa
    45721 atctgtggca aaatggaacg agaagggaaa aagtttggtc taggttctag tggcagcgtc
    45781 gttgtcttgg ttgtcaaggc tttactggct ctctataatc tttcggttga tcagaatctc
    45841 ttgttcaagc tgactagcgc tgtcttgctc aagcgaggag acaatggttc catgggcgac
    45901 cttgcctgta ttgtggcaga ggatttggtt ctctaccagt catttgatcg ccagaagata
    45961 gctgcttggt tgaaagaaga aaacttggcg actgttttag agcgtgattg gggctttttt
    46021 atctcacaag tgaaaccaac tttagaatgt gatttcttag tgggatggac caaggaagtg
    46081 gctgtatcga gtcacatggt ccagcaaatc aagcaaaata tcaatcaaaa ttttttaact
    46141 tcctcaaaag aaacggtggt ttttttggtc gaagccttgg agcaggggaa agccgaaaaa
    46201 gttatcgagc aagtagaagt agccagcaag cttttagaag gcttgagtac agatatttac
    46261 acgcctttgc ttagacagtt gaaagaagcc agtcaagatt tgcaggccgt taccaagagt
    46321 agtggtgctg gtggtggtga ctgtggcatc gccctgagtt ttgatgcgca atcaaccaaa
    46381 accttaaaaa atcgttgggc cgatctgggg attgagctct tatatcaaga aaggatagga
    46441 catgacgaca aatcgtaagg acgagcatat cctctatgcc cttgagcaga aaagttccta
    46501 taatagcttt gatgaggtgg agctgattca ttcttccttg cctctttaca atctggatga
    46561 aatcaatctt tcgacagagt ttgctggtcg aaagtgggac tttccttttt atatcaatgc
    46621 catgactggt ggaagtaata agggaagaga aatcaatcaa aagctggctc aggtggcgga
    46681 atcctgtggt attttatttg taacgggttc ttatagcgca gccctcaaaa atccaacgga
    46741 tgattctttt tctgtcaagt ctagtcatcc caatctcctc cttggaacca atattggatt
    46801 ggacaagcct gtcgagttag gacttcagac tgtagaagag atgaatcctg ttctattgca
    46861 agtgcatgtc aatgtcatgc aggaattact catgcccgag ggagaaagga agtttagaag
    46921 ctggcaatcg catctagcag attatagcaa gcaaattccc gttcctattg tcctcaagga
    46981 agtgggcttt ggaatggatg ccaagacaat cgaaagagcc tatgaattcg gtgttcgtac
    47041 agtggaccta tcgggtcgtg gtggcaccag ctttgcctat atcgaaaacc gtcgtagtgg
    47101 ccagcgtgat tacctcaatc aatggggtca gtctaccatg caggcccttc tcaatgccca
    47161 agaatggaaa gataaggtcg aactcttggt tagtggaggg gttcggaatc cgctggatat
    47221 gattaagtgc ttggtttttg gtgctaaggc tgtgggattg tcacgaaccg ttctggaatt
    47281 ggttgaaacc tacacagttg aagaagtgat tggcattgtc caaggctgga aagcagacct
    47341 acgcttgatt atgtgttccc ttaactgtgc caccatagca gatctacaaa aagtagacta
    47401 tcttctttat ggaaaattaa aagaagcaaa ggatcagatg aaaaaggcgt aaccagcgcc
    47461 ttttttccat cctcagactg aggtgacttt tttgaattgt gataaaatag aagggagagg
    47521 atgaacctat gagaaaattt aaaatctttt tatttatcga agcctgtctt ctgacaggag
    47581 ctctgatttt gatggtatca gagcattttt cgcgttttct gctgatacta ttcctctttt
    47641 tgcttttgat tcgctactac actggtaaag agggaaataa tcttctttta gtagcggtaa
    47701 ccattctctt ctttttcatc gttatgctca atccttttgt gattctagct atttttgttg
    47761 cggttatcta tagcctcttt cttctttacc cgatgatgaa ccaggaaaaa gagcagacca
    47821 atttggtttt tgaagaggtc gtgacggtta agaaggagaa aaatcgttgg tttggaaatc
    47881 ttcatcattt ttcaaactac cagacttgcc aattcgatga tatcaatctc tttcgcttca
    47941 tgggcaagga cactattcat ctggagaggg tcatcttaac caatcatgac aatgtcatta
    48001 tcctcagaaa gatggtagga acgaccaaaa tcatcgtacc tgtagatgtg gaagtcagtc
    48061 tcagcgttaa ctgtctctat ggggatttga cttttttcaa ccagcccaag cgagccctcc
    48121 gcaatgaaca ctatcatcaa gaaacaaaag actatctcaa gagtaacaag agtgtcaaga
    48181 ttttcttgac cactatgatt ggtgatgtgg aggtggttag aggatgaaaa aacaagccta
    48241 tgtcattatt gctctcacct ccttcctatt tgtctttttt ttctcccaca gcttgctgga
    48301 aatacttgat tttgactggt ctatcttttt gcacgatgtc gaaaaaacag aaaaatttgt
    48361 ctttttattg ttggttttca gcatgtccat gacctgtctc ttagccctgt tttggcgagg
    48421 gatcgaagag ctttctctaa gaaaaatgca ggctaatctc aagcgtttat tagcagggca
    48481 agaagtggtt caggttgcag atccagattt ggatgccagt ttcaagtcct tatcaggtaa
    48541 acttaacctt ttgacagagg ctcttcaaaa agctgaaaat cagagccttg ctcaggaaga
    48601 ggaaatcatc gagaaggaac ggaagcgaat tgctcgggat ttgcacgata cagtcagtca
    48661 ggagttgttt gcggcccaca tgattttatc gggtatcagt cagcaggctt tgaaattgga
    48721 tagagaaaag atgcagatcc agttgcagag tgtcacagct attttagaaa ctgcccagaa
    48781 ggatttgcgg gttttgctct tgcatttgcg accagttgaa ctggagcaga agagcttgat
    48841 agaagggatt cagattctct taaaagagct tgaggacaag agtgatctta gggttagtct
    48901 caagcagaat atgacgaaat tgcctaagaa aatcgaggag catatcttcc gtatcctgca
    48961 agagttgatt agcaataccc tccgccatgc ccaggcatct tgcctagatg tctacctcta
    49021 tcagacagat gttgaattgc aactgaaggt ggtggacaat gggattggtt tccagttagg
    49081 gagcttagac gacttgagtt atggactgcg aaatatcaag gagcgggttg aagatatggc
    49141 aggaacggtt cagttattaa cagctcccaa gcaagggctg gcagttgata tccgtattcc
    49201 cctgttagat aaggaatgat aaaggagtaa agatgaaaat tttactagta gatgaccatg
    49261 aaatggtccg tttgggtttg aaaagctact ttgacctcca agacgatgta gaagttgtgg
    49321 gtgaggcgtc caacgggtct caagggattg acttggcctt ggaactgcgt ccagatgtca
    49381 ttgtcatgga tattgtcatg cctgagatga atggaattga cgcgacctta gcaatcctta
    49441 aagaatggcc tgaagccaag attttgattg tgacctctta tttggacaat gaaaaaatca
    49501 tgccagtctt agatgctggt gccaaaggct atatgctcaa gacttctagt gcagatgaat
    49561 tgcttcatgc cgtcagtaag gtagctgctg gcgagctggc cattgagcaa gaggttagca
    49621 agaaggttga ataccaccgc aatcatatgg aacttcatga agaattgact gcgcgtgagc
    49681 gagatgttct ccaactcatc gccaagggct acgaaaatca gcgcatcgca gatgacctct
    49741 ttatctctct caagacggtc aagacccacg tgtccaatat tcttgccaaa cttgaagtca
    49801 gcgatcgtac ccaggcggct gtctatgcct ttcagcacca tttggtgggg caagaggagt
    49861 tttagatgag tttagcagat ttacttgagg agctagaagc agcaaaagac tctaaaaaag
    49921 caaggtccat ggaagcctat atgcgccatc aattttcttt tctaggtatt gcggtgcctg
    49981 aaagaaataa actctataaa aatattttcc agaagcgaaa aaaacaaaga ttatcgattg
    50041 ggattttgca gacacttgct gggaaaagga gcctagaaaa taccaatatg tggctgctaa
    50101 ctatttgaaa gcaatgcagt cttatctaaa ggaaaccgat ttgcctaagc tagagcagtt
    50161 agtcgtgaca aaatcctggt gggacacggt agatatccta gatcgagtag tagggagttt
    50221 ggtgtatgaa caccctgaac tagaagaaat aatcttaata ctcttcgaaa atctcttcaa
    50281 accacgtcag ctctatctgc aacctcaaaa cagtgttttg agcaatctgc ggctagcttc
    50341 ctagtttgct ctttgatttt cattgagtat aaaatggagc ctattagata atatttggct
    50401 gagacgtgtc gctattgacc accagttgtt aagaaaagag aagaccaata ctcaattaat
    50461 ggaaaagatt ctccttcata acttgaacca aacagaattt tttatcaata aagccattgg
    50521 ctggactctg cgagactact ccaaaacgaa tcccacttgg gtaacatgct ttattgagaa
    50581 aaacaaggaa agaatggctg aacttagtat caaagaagca agcaagtacc tctagcgtga
    50641 ttgaaaagcg cagtcattaa ttgaaaagtt tacctgttta tgtgataatg gagggtattt
    50701 aaagaaggtg gtagatttct tgattctata gtagattgag aaatttagaa tagtacacta
    50761 taattacatt aggaggatac gataatgaag aaaactgttt ataaaaaatt gggtatttca
    50821 attattgcga gtactttatt ggctagccag ttatcgacag tatctgcttt gagtgttatt
    50881 tctagtacag gtgaagaata tgaggtaagt gagacactag aaaaaggtcc agggtctaat
    50941 gattcttcat tatctgagat ttcaccaacg tatggttcat actatcaaaa gcaatcagaa
    51001 gtattatcgg taatgatgat ttgattaaaa ttgataatac tttacagtat ccgtattcga
    51061 cttcagctat ggttttatct aagtattatg gagtagccga tggaatgaat gtagaaggga
    51121 ggggaagtgc gaattttatt aaagataatg tgttaattac agcggctcac aactattaca
    51181 gacatgacta tgggaaagaa gcggatgata tttatgttct tccggctgtt agtccaagtc
    51241 aagaactatt tggaaagatc aaagtaaagg aagttcgtta tttgaaggaa tttagaaatt
    51301 taaattctaa gaatgcaagg gaatatgact tggctttatt aattctagaa gagcccattg
    51361 gtgcaaaatt agggactttg ggtcttccta ctagtcaaaa aaatttgaca ggaataactg
    51421 tgactatcac aggctatcca tcatataatt ttaaaattta tcaaatgtat acagataaaa
    51481 aacaagtttt aagtgatgat ggcatgttct tggattacca agttgatact ttagagaggt
    51541 ctagtggatc tgcagtttat gatgctagtc accgcgtagt aggagtgcat actttaggag
    51601 atggagctaa tcaaattaac agtgcagtta aattaaatga acgaaatttg tcatttattt
    51661 atttattcgg ttcttaaagg ttactctctt gaaggatggt gaatgggtta ggtaatgaag
    51721 gttaattgta aactgtgatg gatacttaac tttgtataat aggtggataa aagtctttaa
    51781 aataggaaaa aacgcatatt attaggtgtt taaaaacctt gataatatgc gttttataat
    51841 ggaaagattt cttcaatttc gtcttgtata gtagattgaa actataatag tacacctcta
    51901 cttctaaaac attgttagaa attgatttga ctgtcctgat cgatttgtcc tgttcttatt
    51961 tcgttttact ataatgtaat cgtccaataa cgaagtgttt ttggatagtc cgaaaagttt
    52021 agcttcatat agagtaattg gtattattga tagagtgtta gaaattttaa aagaatatct
    52081 tcttttagaa gaaggtgatt atatatttac aaataatggt tctcccttaa tgataacttg
    52141 tttcaattac tttttgaaaa acagttttag gaaaagtgaa attaagaaag atgattttgt
    52201 attgactgct catgttttta gatattcgca tataagtttg cttgctgaat tggaagtacc
    52261 tataacagcg ataatggatc gtgtagatta tactaatgaa acaaagattt taagtgttta
    52321 tactcatgtt actgagaaga tgaagtcaaa tataactgaa aaattagata aattagtttt
    52381 ggaaagtgac taaccaaaag atatccaaag tagtctaaaa ttgtctatac tttatgagtg
    52441 ttttagttag gaaaaaggct tgttgtctat aattgtctgc attagtctag attttattta
    52501 tagaaaatgt tataatagac tgtatttaaa aaattttaag gagaaatgac agaatgtctg
    52561 tatcatttga aaacaaagaa acaaaccgtg gtgtcttgac tttcactatc tctcaagacc
    52621 aaatcaaacc agaattggac cgtgtcttca agtcagtgaa gaaatctctt aatgttccag
    52681 gtttccgtaa aggtcacctt ccacgcccta tcttcgacca aaaatttggt gaagaagctc
    52741 tttatcaaga tgcaatgaac gcacttttgc caaacgctta tgaagcagct gtaaaagaag
    52801 ctggtcttga agtggttgcc caaccaaaaa ttgacgtaac ttcaatggaa aaaggtcaag
    52861 actgggttat cactgctgaa gtcgttacaa aacctgaagt aaaattgggt gactacaaaa
    52921 accttgaagt atcagttgat gtagaaaaag aagtaactga cgctgatgtc gaagagcgta
    52981 tcgaacgcga acgcaacaac ctggctgaat tggttatcaa ggaagctgct gctgaaaacg
    53041 gcgacactgt tgtgatcgac ttcgttggtt ctatcgacgg tgttgaattt gacggtggaa
    53101 aaggtgaaaa cttctcactt ggacttggtt caggtcaatt catccctggt ttcgaagacc
    53161 aattggtagg tcactcagct ggcgaaaccg ttgatgttat cgtaacattc ccagaagact
    53221 accaagcaga agaccttgca ggtaaagaag ctaaattcgt gacaactatc cacgaagtaa
    53281 aagctaaaga agttccggct cttgacgatg aacttgcaaa agacattgat gaagaagttg
    53341 aaacacttgc tgacttgaaa gaaaaatacc gcaaagaatt ggctactgct aaagaagaag
    53401 cttacaaaga tgcagttgaa ggtgcagcaa ttgatacagc tgtagaaaac gctgaaatcg
    53461 tagaacttcc agaagaaatg atccacgaag aagttcaccg ttcagtaaat gaattccttg
    53521 ggaacttgca acgtcaaggg atcaaccctg acatgtactt ccaaatcact ggaactactc
    53581 aagaagacct tcacaaccaa taccaagcag aagctgagtc acgtactaag actaaccttg
    53641 ttatcgaagc agttgccaaa gctgaaggat ttgatgcttc agaagaagaa atccaaaaag
    53701 aagttgagca attggcagca gactacaaca tggaagttgc acaagttcaa aacttgcttt
    53761 cagctgacat gttgaaacat gatatcacta tcaaaaaagc tgttgaattg attacaagca
    53821 cagcaacagt aaaataatct taataaacag aaaacccacc tgaattggtg gtttttctga
    53881 tgcactattt tccaaaaatc tctttgaggt ctgtgtctgt aatcccaatc atggctggaa
    53941 tgctgtccca gttttcttcg gttaggatgt aggattgttc agaggcactt gatgtgactg
    54001 tttcagagac agcttgttgc ttttcttcaa cattctccag tagatcactg aagcgttcaa
    54061 tcagataggt ttttcgggca gttccgatgt gttgggtagc atagtcgaag gcttgtaatt
    54121 cgcctagtaa gatgagtttg cttttggcac gtgtaatggc tgtgtagatg agatttcgct
    54181 ccagcatacg tcggctagca ctagtaatcg gtaggatgac aactgggaac tcacttccct
    54241 gagacttatg aatactcatg gcataggcca agcgaatctt gtaccattcg ttacgggggt
    54301 aagagacttc attaccatca aaatcaatga caatctcgtc ttgtttcgat tcggtgtatt
    54361 taccaggaat caggtctgtg atagctccta aatccccatt aaagacattg atttcagcat
    54421 cgttaaccaa atgaatgacc ttgtctccct tacgatagtg gcactgagga gcttcaaaac
    54481 tgagttgatc tttttgtggg ggattgagca ggtcttgcat gagctgattg atagcatcaa
    54541 tccctgccgt ccctcggtac ataggagcca gaacttggat atcacgggca ggaataccat
    54601 ttctgagggc ggcacctaag attttttcaa tggtggcagg aatatggcca ctagcaattt
    54661 caaagtagga acggtcagct tttttttggg tgaaatcagc tggcaagatg ccctgtcgaa
    54721 tctgactagc tagggtgacg atggttgatt cttcgctttg tcgataaatt ttttccaagc
    54781 gagtctgagg aatcaaagga atatgaagca gatccgctag aacctgtcca ggactgacag
    54841 aaggtagctg atcactgtca cctacgatga ggatcttact gttagaagag atattggaga
    54901 agagttgatt ggccagccaa gtatccacca tagagaattc atccacgatg ataaagtcag
    54961 catctaggta atcttccaga tgactggtat catcgtcacc tgtcattccc aagtggcggt
    55021 gtatggtcgc gctaggcaaa cctgtcaatt cattcatgcg acgagcagct cgaccagttg
    55081 gagcagcaag aagaatgggc aggttgcttt tcttcctgag gtcaagtccc tctaacaggg
    55141 cgtaaacagc gatgatccca ttgataacag ttgtcttacc agtaccaggt ccacctgtca
    55201 ggataaagac cttattctgg atagcatcac agatagcctg tttttgaatg ttatcatact
    55261 caattccaag ctctttctcg atagtagtga tatgtttttg aatggttttt aaatcatgac
    55321 tcttctgttt tcctttttca aggatacgaa ccaagtgact gcggatgcct tcctcagcga
    55381 aaaagaggct gttgtcaaag atcttggtat caatctgctg aaccttgtct tcttcgatca
    55441 ggtaggagag ctcttgggca acttggctgg ggtctagttc cacgggacgg gaagactcaa
    55501 ggagagtaag ggtttgttcc agcaaatccc gtgcttcaac ataggtgtct cctgtttcca
    55561 tacaggcctg aaaaagactg tgaactagac cggcgcggaa gcgttcagga gcctgacttt
    55621 cgatgcctag ttcctcagct agttggtcag caatggtaaa gcccaaaccc ttgatatcct
    55681 caaccagttg gtagggataa ttttcaacca catcaagggt ttcttccttg taaaagtctt
    55741 gaatctgaaa ggctagtttg ttgggaatgc cgtagttggc tagtttggcc aaaaccatct
    55801 ccgtaccgta gttgagacgg agagtggaga cgaaagcctc gcgatttttg gcagagagtc
    55861 ctgcgatgcc ttctaacttt tctgggtgtt gcaaaatttc gtcaatggta ttttcgccat
    55921 aggtatccac gattttctga gctgtcttga gaccaatccc cttgaaatgg ctacttgaaa
    55981 agtacttgac caagccctta ctagttggtt ttgcgcgatc ataacgactg atttgcagtt
    56041 gttctccata cttggagtgc tggacaattt gcccccaaaa agtatagtct tcgccctcaa
    56101 ttacatcagc catggttcct gtgacaatga tttcaaagtc atcaaaatcc tctgcgtccg
    56161 tatcgtcgat ttctaggagg aggatgcgat aaaaattgct gggattttca aaaataatcc
    56221 gttcaatggt tcctgaaaaa taaacttcca taaaattcct ttgcatgaat aggtgagagt
    56281 tgggattgtt tttattttat actcttcgaa aatatcttca aaccacgtca gcttccatct
    56341 gcaacctcaa aacactgttt taagcagcct acggctagct tcctagtttg ttctttgatt
    56401 ttcattgagt atttgtcaat aaacaatcac ttctcacgat agaagaagag gctgagattg
    56461 gtgattctcg gcctcttagg tttcttaaaa tgttccgata cgggtgattg gccagaagcg
    56521 gaatttagct tcccctgtga tatcttttgc tttgaaggta cctacgtggc ggctgtcgct
    56581 cgaaaccaag cggtcatctc cgaggagaag gtattctcct tctggaacag taaagctaaa
    56641 gttggtgttg tagttgacat caactgtgaa ggcttgggct ttttgagcga tacttctaaa
    56701 gaaagttcct ttatttcctt caaagccctt gcctgagtaa gtgctttgga gtttgtcatc
    56761 cttgaagcgt ttgatatagt ctgctagata aggctcgtcc gtttctttgt cattgatgta
    56821 gagtttatca ttttcgtaac gaatggtgtc gccaggcatt ccaatcacgc gcttgacgat
    56881 gtccttattg ccatcttcct catgggccac cacgatatca aaacggtcaa taggaaggtg
    56941 ttttacaacg aagagaattt cgccatccgc tagggtcgga tccatggaat gtccttctac
    57001 gcgaacattg ctccaaaaaa agatacgact taaagctagt aatgacagaa ttaggaggaa
    57061 caatccccac tcttttaaga aatttttaaa tgaattcata acttaccttt ctaagcgttt
    57121 tttcgctttt tcagtgtttt taaagtgcaa tttggcgcag aagctgagtc cctgcatacc
    57181 ataggcttgc aaaatctggc tagccacctt gtcagaagct gttccagctc cacttgggag
    57241 ctgataaccc agttctcgtc ccagattttc aagattttcc agaaagagat cacgcgcaat
    57301 gacagaagaa actgcgacag ccaagtattt gccctcagcc ttttcttcta agctgatagg
    57361 attgctgaaa cgattggcct cttgtgccaa gtacttgtca taatttttag cactggtaaa
    57421 ggcatcaatc acaattttct caggctgaac acctttttga aggaggagat agatagcctg
    57481 attatggagg gcaaccttaa ccgaaacagc attgtagcgg tctccgatga cctcgttgta
    57541 cttgctgggt gagagaagga gtgcctggtg ctgaattttt tccttgagaa taggagcaat
    57601 ctgacggatc ttttggtcgg tcagagtctt agaatccccc acaccgagtt ttcgtaaaaa
    57661 gtcgtgctgg tcaggtgtga caaaggcagc cacaactgca agcccaccaa agtaggaacc
    57721 atttcccacc tcatctgtcc caattaaagg aagattttgt ccgctggttt gctctacagc
    57781 ttgatagcca aagaaactgg cgtatttttc agccccttca ccctgaagca agatttttcc
    57841 agaagtatag atagaaaccg ttgcttgagg tagtttcaaa aagtagcgga tatagggatt
    57901 cttgctagga gccagactgg tttgatagtg ttcaagaaaa gcctgaatat ccttttcgct
    57961 tggtgtgagt gtgatacttg ccatagtttc tattgtacca caaaagcagt aaaatttgta
    58021 aaaactgaca aaattagcga attttggtat aatatcgtga ggtgaatttt atggcaaatc
    58081 taaatcgatt caaatttaca ttcgggaaaa aatcgttaac cttgacaagc gaacatgata
    58141 acctttttat ggaggaaatc gctaaggttg cgacagaaaa ataccaagca attaaagaac
    58201 aaatgcctag cgcagatgat gaaacaatcg ctcttttgtt ggcagtcaac tgtttatcaa
    58261 ctcagctcag ccgtgagatt gaatttgacg ataaggagca agagctagaa gaactccgtc
    58321 acaagcttgt gacttgtaag caagaacaga gcaagattga ggattcctta tgatttcatt
    58381 ccttcttcta ttggtcttgg tttggggatt ttatatcggc tatcggagag gcctgctctt
    58441 acaggtttat tacctgattt cagccatggc atcggctttt atggctggcc agttttataa
    58501 ggggcttgga gagcaattcc atttattgct cccttatgca aattcgcagg aaggtcaggg
    58561 gactttcttt ttcccatcgg atcaactctt tcagctggat aaggtctttt atgcaggcat
    58621 cggctacttg cttgtatttg ggattgtcta tagcattggt cgtttgcttg gtcttctctt
    58681 acacttgatt cctagcaaaa aactgggtgg taagttgttc caagtttcag caggtatctt
    58741 gtccatgttg gtgaccttat ttgtcttgca aatggccttg acaatcttgg cgaccatccc
    58801 catggcagtt atacaaaatc ctcttgaaaa gagtatcgtc gcaaaacaca tcatccagag
    58861 cataccgata acaaccagtt ggctcaaaca aatctgggtg acaaatttaa tcggataaaa
    58921 agggcaggag ttttcctagc cctttgttta cagatttgac tcgaatctat cagaatgtaa
    58981 aaagctacca cacctagaca ttcaaagaca aggaaataaa gatgaataag aaaatattag
    59041 aaacattaga gttcgataag gtcaaggcct tgtttgagcc tcatttgttg accgagcagg
    59101 gcttggagca attgagacaa ctggctccga ctgccaaagc agataaaatc aaacaggctt
    59161 ttgctgagat gaaggaaatg caggctcttt tcgtcgagca accgcatttt actattctct
    59221 caactaagga aattgcagga gtctgcaaga ggttggagat gggagcggat ctcaatatcg
    59281 aggagttcct actcttgaaa cgcgtgcttc ttgccagccg agaacttcaa agtttttacg
    59341 ccaatctgga aaatgtcagc ttggaagaat tagccctttg gtttgagaaa ttacatgatt
    59401 ttccgcaatt acaaggaaat cttcaggcct ttaatgatgc gggtttcatt gaaaattttg
    59461 ccagtgaaga attggcgcga atccgtcgaa aaatacatga tagcgagagt caggtacgcg
    59521 atgttttaca agacttgctc aagcaaaaag cgcagatgtt gacagaagga attgttgcta
    59581 gcagaaatgg ccgtcaggtt ttaccagtca aaaacaccta ccgcaataag attgcaggtg
    59641 tcgttcatga tatttctgct agtggaaaca ccgtctatat cgaaccacgt gaggtagtca
    59701 aactgagcga agaaattgct agtctgcgag cagatgagcg ctatgaaatg cttcgcattc
    59761 tccaagaaat ttctgagcgt gtccgccctc atgcggctga gattgctaat gacgcttgga
    59821 ttatcggtca tctggacttg attcgtgcca aggttcgatt tatccaagaa agacaagcag
    59881 tcgtgcctca gctgtcagaa aatcaagaga ttcaactgct ccatgtctgc catcctttgg
    59941 tcaaaaatgc cgtcgcaaat gatgtctatt ttggtcaaga tttaacagct attgtcatta
    60001 caggtcccaa tacaggtggg aagaccatca tgctcaaaac tctgggcttg acacaggtca
    60061 tggcccagtc aggattgccg attttagcag acaagggaag tcgtgttggt atttttgaag
    60121 aaatctttgc tgatattgga gatgagcagt ctattgagca gagcttgtct accttctcta
    60181 gccatatgac caatatcgtg gatattcttg gtaaggtcaa ccaacattca ctcttacttt
    60241 tggatgagtt gggggctggt actgatcccc aagagggagc agcccttgcc atggctattc
    60301 tggaggacct tcgcctgcgt caaatcaaga ccatggcgac gacccactat ccagaactca
    60361 aggcctacgg tattgagaca gcctttgtgc aaaatgccag tatggagttt gatactgcaa
    60421 ctcttcgccc gacctatcgc tttatgcagg gtgttcctgg ccgaagtaat gcctttgaaa
    60481 ttgccaaacg tctaggccta tctgaagtta tcgtaggaga tgccagtcag cagatcgatc
    60541 aggacaatga cgtcaatcgt atcattgagc aattagaaga gcagacgctg gaaagccgca
    60601 aacgcttgga caatatccgt gaggtggagc aagaaaatct caagatgaac cgtgcgctaa
    60661 aaaaactcta caacgagctt aatcgtgaaa aggaaaccga gcttaacaag gcgcgtgaac
    60721 aggctgctga gattgtggat atggccctaa gtgaaagtga ccagattctc aaaaatctcc
    60781 acagtaaatc ccaactcaag ccccacgaaa tcattgaagc caaggccaag ttgaaaaaat
    60841 tggctcctga aaaagtggac ttgtctaaaa acaaggtcct tcaaaaggcc aagaaaaaac
    60901 gagctccaaa ggtgggagat gatatcgtgg ttctcagtta tggtcagcgt ggtaccttga
    60961 ccagtcaact caaggacggc cgctgggaag cccaagttgg cttgattaag atgaccttgg
    61021 aagagaaaga gtttgatctt gttcaagccc agcaagaaaa agcagtcaag aagaaacagg
    61081 tcaatgttgt gaaacgaact tctgggcgag gacctcaagc tagactggat cttcgaggca
    61141 agcgctatga agaagccatg aatgagctag ataccttcat cgaccaagcc ttgcttaaca
    61201 atatggctca agttgatatc atccatggta tcggaacagg agtcatccgt gaaggagtta
    61261 ccaaatactt gcaaagaaac aaacatgtca agagtttcgg ctatgcccca caaaatgctg
    61321 gaggcagtgg tgcgactatt gtcactttta aaggatagca gtattctgga ctttataaag
    61381 taaaaactgt tgaactaatt tttactaata aacacattga caaaagccaa cattttttgt
    61441 aaaattagaa tcaattaata ccaacaccga atgaagttta atagaagtgg ggaatcgttt
    61501 gattttccat gactgtaaat ggacggaact ctggagagac cgtaaaggca ccgaaggggc
    61561 aaggcaggca actgctcaaa ctctcaggta aaaggacaga gctaggatag accgcttttt
    61621 agcatttatc taagcattcc agagtacatg tatcttgcat gtgctctttc ttttggggtt
    61681 gaaacgatag gagaaggaaa tgttagaatt gcttaaatca atcgatgctt ttacttgggg
    61741 accgcccctc ttgattttat tggtcggaac aggggtttac ctaaccatgc ggctaggact
    61801 cttgcaggtt ttgcgtctgc ccaaggcctt tcagcttatt tttatccagg ataagggaca
    61861 tggtgatgta tccagttttg cagctctgtg tacagccttg gcatcaactg ttggaacagg
    61921 aaatatcata ggagttgcga cggcgatcaa ggttggtgga ccaggagctc tattttggat
    61981 gtggatggcg gctttctttg gaatggctac caagtatgcg gaaggactct tggccatcaa
    62041 ataccgcacc aaggacgacc atggtgcagt agcgggaggt cccatgcact atatccttct
    62101 agggatggga gaaaagtggc gaccacttgc tgttttgttt gcagtagcag gagtattggt
    62161 tgctctcttg ggaatcggaa ccttcaccca agtcaactcg attacagaat ctatccaaaa
    62221 tacaacgacg atttcgccag ccatcacagc tctcgtcttg tctgtctttg tagcgattgc
    62281 agtctttggt ggactcaagt ctatttctaa ggtttcaact actgttgttc cttttatggc
    62341 cctcatttat atcttaggaa ctcttacagt tattttcttt aatatcggaa aaatccctgg
    62401 cacaatcgct ttagtcttta cctcagcttt tagtcccctt gctgcggtag gtggatttgc
    62461 tggtgctagc gttcggatgg ctattcaaaa tggtgtggcg cgtggtgtgt tctcaaacga
    62521 atctggtctg ggttctgctc ctattgcagc tgcagctgcc aagacaaatg aaccagtaga
    62581 gcaaggtttg atttccatga caggaacctt tattgatacc ctcatcattt gtactctaac
    62641 tggtttgacc atcttggtaa ctggagtttg gagcggtgac ttgaatgggg ttgccttgac
    62701 tcagtcagct ttctcaacag tcttttcaca ctttgggcct gctctcttga ccatcttcct
    62761 tgtacttttt gcctttacaa cgattctagg ttggaactat tacggagaac gctgttttga
    62821 gttcctcttt ggggttcgct ttatctggct ctaccgtgtg gtttttgtgc tcatggtctt
    62881 gttaggagga tttatcgagt tggatatggt ctggattatc gcagatatcg ttaacgcctt
    62941 gatggctctg ccaaacttga ttgccctctt ggtcttgtcg ccagtcgtta ttgctgaaac
    63001 taaaaagtat tttgacaaat aatggaatca cacagctcgt gtgatttttt tgcctataaa
    63061 taatttttat cagcctgata tataatatat attatgcaag tgattggaag tgtgataaac
    63121 taatataaca acgaaaatct tatgagagaa taaagcttta tcttagataa acttaggaat
    63181 caggatttta taagattttc caataatatt agtgtcaata ataagaaaag aggtatctta
    63241 tgacaacatt tactatccat acagtagagt cagcaccagc agaagtgaaa gaaattcttg
    63301 aaacagtaga aaaagacaac aatggctata ttcccaacct aatcggtctc ttggccaatg
    63361 ccccgactgt tttagaagcc taccaaattg tctcatctat ccaccgtcgc aacagcctga
    63421 cacccgttga gcgtgaagtg gtgcaaatca cggcagccgt gaccaatggt tgtgccttct
    63481 gtgtcgcagg tcacacagcc ttttccatca aacaaatcca gatgaatgat gacttgattc
    63541 aagctcttcg caatcgtact ccaattgaaa cagatcctaa attggatacc ctagctaagt
    63601 ttaccttggc agttatcaat accaagggtc gtgtaggaga tgaagccttg tctgagtttt
    63661 tagaagctgg ctacactcaa caaaatgcct tggatgtggt ttttggtgtc agcctagcaa
    63721 tcctctgtaa ctatgccaac aacttagcta atacaccaat taatccagaa ttgcaacctt
    63781 atgcctaatt catatctgag taaaatgaag tctgaaataa tcggacttcg tttttttaaa
    63841 tcctcattta agcgctttta tgttatactg aaactaacat gattattgga ggttaggatg
    63901 aaaaaactcc ccttagtatt ttcaggttgt ttgctaggtt tggcaggagc tggaaatctt
    63961 attttagata cgttgccagt tctatcccat ctttttagtc tgactggttt ggttttatgg
    64021 atttactttc taattctgca tctctttaat tggaaagaaa ccaagcaaga attgaccaag
    64081 ccccctcttt tgtcaggaat ggcaaccttt cctatggctg ggatgatttt atcgacctat
    64141 gtctttcgcg tattctctta tcttcctttg gtagcacaag ggatttggtg gttttcattt
    64201 ctcttggatt tgaccttgat tgctggtttt accatcaagt ttgcttgtcc agggcggagg
    64261 gttcatgcca ctccaagttg gacggttctc tatgtgggga tagcagtggc tgccttgacc
    64321 tatcctctgg taggtattat cgaaattgcc tatgcgacct tgagttttgg ttttctcttg
    64381 accttctatc tctatcccct tatttatagc gatttaaaga aacatccact cccactagcc
    64441 ttgcttggac aagaaggaat ctactgtgct cctttctctc tactcttggc ttctctagtt
    64501 cgagtaggag gaaccagcct gccgaattgg gtcttgattg tcatgatttt ggcttctcaa
    64561 tccttctttt tctttgtttt aactcgtctg cccaacattt taaaacaagg ttttcaacca
    64621 gccttctcag ccctcacctt cccaaccatt atcacagcga cctcgctcaa gatggctcag
    64681 ggaattttga aacttccatt tctggattac ctggtattgg ctgaaaccat tatatgccta
    64741 actattttat tctttgtact aggtgcttat ctgatttggt tacgaaaaaa ggtctagcta
    64801 gaaatagcta aaccttattt tttatggttt gatgacttca gctccaccca tgtatggacg
    64861 aagtgcttct gggatggtca cagaaccatc ttcattttgg taattttcaa gaattgcagc
    64921 cactgtacgt ccaactgcaa gtccagaacc gttcaaggta tgaaggagtt tcaccttgcc
    64981 atctgcttca tcacggtaac ggatttgggc acgacgggat tggaaatctt ctgtgtttga
    65041 acagcttgag atttcacggt aattgttttg tgctggaatc cacacttcca agtcgtaagt
    65101 cttcgtagct gagaagccca tatctccagt agagagagca acgacacggt atggaaggtt
    65161 gagtttttga agaatgtttt cagcgttggc tgtcattttt tccaattctt cgtaagattc
    65221 ttctggtttg gcaaatttga ccatttcaac cttgtggaat tggtgcaaac ggatcaagcc
    65281 acgcgtatca cgaccggcag aaccagcctc agaacggaat gacggactca tagcagtgaa
    65341 gtagattgga agatctttgc cgtctaagat ttcatcacgg tagtagtttg tcagaggaac
    65401 ttcagcagtt ggaatcaaga caaagttggt atcgctgagt tcaaaagtat cttccttaaa
    65461 ttttggatac tgaccagtac caaacataga atcatggttg actatgtaag gtgtgatgac
    65521 ttcagtatag ccttcttttc catgttcatc caacataaag ttgtagatag cacgttccaa
    65581 acgagcaccg aggcctttat agaagaggaa gcgagcgcct gttaccttac caccgcgttc
    65641 ccagtcaagg ataccaaggt cttcaccgag atcccagtga gctttaggtt cgaagtcaaa
    65701 ctcgcgtgga gtaccccaac ggcgaacttc cacattgtcg tcttcgtcag ccccaacagg
    65761 aacgctgtca gctgggatat ttggaagagt cgttgtaaat tctgtcaatt tagcatcgat
    65821 ttctgccaat tcagcatcca aggctttaac ctcagcagat agattttgca tggcagcaat
    65881 cttgtcatct gtattttcct tgttgcgctt agcttgggca atctcagcag aaactgtgtt
    65941 acgttctgct ttgagagttt caaccttgac caagatgtta cgacgtttag catcgatttc
    66001 tttcatttca ttcaagacag cagcatctac accacgtgta gctaattttt ctgcgacagc
    66061 ttcaaaatct gtacgaatac gtttgatatc taacataaga actcctttat gaaaaaagca
    66121 cgcctgacaa aacgttggag tggcagggcc acggttccat ccaacttcac aggtgtgcac
    66181 ttgattgtgt atgtaattgt tactaacggt agaatttcac ctatccctcc tatctgctcg
    66241 cagcacccgc agactttctg aaagaagaag ataacctact tatccgttgc tatgattata
    66301 ctaaagtttc tacttttttg caaatagatt tttaaatttt tggctaattg tctgaatcag
    66361 ggtcggaagt ttgacgacct tgtcattgcc tagtttttcg cgtgcaattt tgagaatggc
    66421 acctgagtct tttgaagcaa agaggaattt tcctttgtct gtaaagactt cgaagtggcg
    66481 gctgattttg cgtccagtga cattggctcc aatctgattg atatggctcc aaggaatctg
    66541 gataaattgt tcgacattga catctgggta aaattccaaa gcctgatctc cgacaaggaa
    66601 tttcccaact ttcccagcga tagagaggta ggaagtgcct gtcgtactga ggagtactgt
    66661 tttgttaagt gattgggcca tgcttagtct tccttacttt ctccaaaaaa ggcattgtag
    66721 agggctttaa ttgctgcttt ctcttggtct ttattgacaa caaacataat agaaacttca
    66781 ctagaacctt gagacatcat ctggatgttg attttgtttt cagatagagc gcgtgtcgca
    66841 gtagcagtca ctccgatgtg gctcttcatt ttttcaccaa caatcataat gatagaaagg
    66901 tcgtgttcga tttctgcatg atctacttta gtcttttgaa ccaactgacg caggatttct
    66961 tcttccttga tgggagttag ttcgcgagaa cggagaatga tagaaagatc gtcgatacct
    67021 gttggcatat gttcccaacc gatgttaagt tcttccagga tttgcagaac cttgcggcca
    67081 aatccaacct cacggttcat gaggtatttc gacatgttaa tgctgacaaa gcctgagtca
    67141 gcagcaattc ccacaactgg aaattcatca ttactgtgtt ttagaacgat acgagtacct
    67201 ggatggtcag ggttgttggt attcttgata accagaggaa tttttccacg gtaggcagga
    67261 agaagagcct cgtcatgaag gactgagaag cctgcatagg ccaactcgcg catttcacgg
    67321 taggtcaact caggaatcga gtgtggttgg tggataatac cagggtgggc tgcaaagata
    67381 ccatcaacgt ccgtaaagtt ttcatagagg tcagctttga caccagcagc aatgatagaa
    67441 cctgtaatat cagaacctcc acgtgagaaa gtacagattt gattttcctt agtgacacca
    67501 aagaaaccag gaatgacaag gacttcattg gtgtttgtca attcttcaat cttgtcataa
    67561 cttgatggaa tgatgcgagc gtgaccaggt tcacttgtga ccacaatccc agcttctcta
    67621 gggtgcatat agcgtgcatc gataccattt tggttaaagt aggcagcaat caatttggca
    67681 ttgttatttt caccggctgc taggaaagta tcgtagagaa attcattttc ttcaatagga
    67741 agagtggcca aggcgtgaat gcttttagaa attttttcta gcacagctgg ttttagtccc
    67801 aattcactaa ccatagcagc atagcggtcg ataatccagc tttggctctt gctaatatcg
    67861 ttacccgcaa catagtcgcg gtagtattta atcagggcat ccgtaacctt agtatcttca
    67921 gcattgcgtt taccaggcgc agaaacgact acaaaacgac gctctgaatc gcttttgacg
    67981 atgtttaaaa ctttttctaa ttgactagca gaggcaagag aactacctcc aaatttaaca
    68041 actttcataa gaactcctaa agtaagtatt ttatacgatt atagcagaaa gaaaggcttt
    68101 tttcaatgaa gaaaataaga tgctttctag cctaaagcga gcctttctta tcggctgaga
    68161 cactttcagt cgattttttc ttgctttctg ctcctaaaaa agatatactt tgacagtgaa
    68221 ataatttaac actcaatgaa atcaaagagc aaactaggaa gctagccgca gactgctcaa
    68281 agcactgctt tgaggttgta aataagactg acgaagtcag ctcaaaatac tgttttgagg
    68341 ttgcagatgg aagctgacgc ggtttgaaga gattttcgaa gagtataaac tgcttataaa
    68401 ataaaaagga gccctgatgg aacacattat ttatcagctt gaagaggact tggcaatcct
    68461 taccttgaac cgtcctgagg tcgcaaatgg ttttcatatt cccatgtgtg aggagatttt
    68521 agaagctctg actttggcag aagaaaatcc agctgtgcat tttatcttaa tcaatgccaa
    68581 tggaaaggtc ttctcagttg ggggagattt ggtagagatg aagcgggcag tggatgagga
    68641 tgatattcca tcattgacaa aaatcgcaga gttggtcaat acgatttctt ataaaatcaa
    68701 gcaaatagcc aaacctgttt taatggaagt tgacggtgct gttgcaggtg ccgcagcgaa
    68761 tatggctgtt gcggcagatt tctgtttggc gacggataag gctaagttta tccaagcctt
    68821 tgttggtgtt ggtttggctc cagatgcagg gggaattcat ctcttgagcc gcagtatcgg
    68881 tgtgacgcgt gctgctcaat tagctatgac aggagaggct ttaacggcag aaaaagccct
    68941 agaatggggg ttggtttacc gcgtttctga agctgaaaaa cttgaaaaga cgagagaaca
    69001 gcttcttaaa aaattaagac gtgcttcaag taattcctat gctgccatta agaagttggt
    69061 ttgggagagc caatttaaag actggcaggg ttacgctact ttagaactga acctacagaa
    69121 atccttagct caaacagagg atttcaaaga aggagtgcga gctcattcgg agagaagaag
    69181 acctaaattt acaggaaaat aaaaaatact tgcatcattc tttgaatttt gatataattc
    69241 tttctgtcaa atgttttgat tgtaaaagtt ttttgaagaa ggagggatat gaaaaatgga
    69301 ctaccaacga atcaatgaat atttaacatc tatatttaac aatgtccttg taattgagga
    69361 agtgaacttg agaggtagtc gttttaagga tatctccatc aaagaaatgc atacgattga
    69421 tgtcatcggt aaggctccag atgtgactcc aagtcaagtg tcaaaagagt tgatggtaac
    69481 tcttggaact gttacgacaa gtttgaacaa tttagagcgt aagggctaca ttgagcgagt
    69541 tcggtcagaa caggatcgtc gtgtggtgca tctgcatttg acaaagaagg gtcgcttgat
    69601 tcatagactg cataaacgct tccacaaggc catggtagaa aaaattattg atggcatgag
    69661 cgaggaagaa attgctgtca tgggtaaagg tttgactaat ctttaccaat ttttggagga
    69721 tttgaaataa tggcttttgc aaaaataagt caggttgctc attatgtgcc agagcaagtg
    69781 gttacaaatc acgacttggc tcagattatg gataccaatg atgagtggat ttcaagtcga
    69841 acgggaatac gacaaaggca tatttcaaga acagaatcta ccagtgattt ggctacagag
    69901 gttgctaaga aactgatggc aaaagctgga ataacaggag aagaactgga ttttatcatc
    69961 ctagctacca ttactccaga ttcgatgatg ccctctacag ctgctcgtgt tcaagctaat
    70021 attggtgcta ataaagcctt tgcttttgac ttaaccgcgg cttgcagtgg atttgtattt
    70081 gctctttcaa ctgctgaaaa gtttatcgct tctggtcgct ttcaaaaagg cttggtgatt
    70141 ggtagtgaaa ccctctctaa ggcagtcgat tggtcggatc gatcaacagc tgtgttgttt
    70201 ggagatggtg ctggtggtgt cttgttagaa gctagcgagc aagagcattt cttagctgag
    70261 agtctcaata gcgatggaag tcgcagcgag tgtttaactt atgggcattc aggtttgcat
    70321 tctccatttt cagatcaaga aagtgcagat tcgtttttga agatggatgg acgcacagtc
    70381 tttgattttg ccattcgaga tgtagccaag tctatcaagc agactattga tgaatctcct
    70441 atagaggtga cagacttgga ttatctgcta cttcatcaag ccaatgaccg tattttggat
    70501 aagatggcta gaaaaattgg tgttgaccga gccaaacttc cagccaatat gatggaatat
    70561 ggcaatacca gtgcagccag tatcccgatt ttactttcag agtgtgtaga acaaggtctc
    70621 atccctttag atggtagcca gactgttctt ctatcaggct tcggtggagg cttgacctgg
    70681 ggcacgctca ttcttacaat ttaggtaatc atgtggtgaa cacattgtta taaaaaaact
    70741 atttatttta aaggagtcct atcatggcag tatttgaaaa agtacaagaa attatcgttg
    70801 aagaacttgg aaaagacgca tcagaagtaa cacttgaatc aacttttgat gatttggacg
    70861 cagattcatt ggacttgttc caagtaatct cagaaatcga agatgctttt gatatccaaa
    70921 tcgaagcaga aaatgacttg aaaacagttg gtgacttggt tgcttacgtt gaagagcaag
    70981 caaaataagc agaatattag tagaaggagt agggagaaac ccactccctc ttgtttaggt
    71041 aatagtttga ctgtcaaatt atggtgaaat cgaactatta cgtaagcaag gaaggttgga
    71101 ggcactatga aaacgcgtat tacagaatta ttgaagattg actatcctat tttccaagga
    71161 gggatggcct gggttgctga tggtgatttg gcaggggctg tttccaaggc tggaggatta
    71221 ggaattatcg gtgggggaaa tgccccgaaa gaagttgtca aggccaatat tgataaaatc
    71281 aaatcattga ctgataaacc ctttggggtc aacatcatgc tcttatctcc ctttgtggaa
    71341 gacatcgtgg atctcgttat tgaagaaggt gttaaagttg tcacaacagg agcaggaaat
    71401 ccaagcaagt atatggaacg tttccatgaa gctgggataa tcgttattcc tgttgttcct
    71461 agtgtcgctt tagctaaacg catggaaaaa atcggtgcag acgctgttat tgcagaagga
    71521 atggaagctg gggggcatat cggtaaatta acaaccatga ccttggtgcg acaggtagcc
    71581 acagctgtat ctattcctgt tattgctgca ggaggaattg cggatggtga aggtgctgcg
    71641 gctggcttta tgctaggtgc agaggctgta caggtgggga cacggtttgt agttgcaaaa
    71701 gagtcgaatg cccatccaaa ctacaaggag aaaattttaa aagcaaggga tattgatact
    71761 acgatttcag ctcagcactt tggtcatgct gttcgtgcta ttaaaaatca gttgactaga
    71821 gattttgaac tggctgaaaa agatgccttt aagcaagaag atcctgattt agaaatcttt
    71881 gaacaaatgg gagcaggtgc tctagccaaa gcagttgttc acggtgatgt ggatggtggc
    71941 tctgttatgg caggtcaaat cgcagggctt gtttctaaag aagaaacagc tgaagaaatc
    72001 ctaaaagatt tgtattacgg agccgctaag aaaattcaag aagaagcctc tcgctggaca
    72061 ggagttgtaa gaaatgacta aaacagcctt tttatttgct ggtcaaggtg cccagtatct
    72121 agggatggga cgggatttct atgatcagta tccgattgtt aaagaaacga ttgatcgagc
    72181 gagccaggta ctaggttatg atttgcgtta tctcatcgat acggaagagg acaaactcaa
    72241 tcagacccgc tatacgcaac cagccattct agcgacttcg gttgctatct accgtttatt
    72301 gcaagaaaag ggctatcagc ctgatatggt tgctggtttg tctcttggag aatactctgc
    72361 cttggtggca agcggcgcct tggattttga agatgcggtt gccttggtag ctaagcgtgg
    72421 agcctatatg gaagaagcgg ctcctgctga ctctggcaag atggtagcag ttctcaatac
    72481 gccagtagag gtcattgaag aagcctgtca aaaagcttct gaacttggag tggttactcc
    72541 agccaactat aacacacctg cacaaatcgt cattgctgga gaagtggttg cagttgatcg
    72601 agcggttgaa cttttgcaag aagcaggtgc caaacgcttg attcctctta aggtgtcagg
    72661 tccatttcac accgctctcc ttgagcctgc tagccagaaa ctagctgaaa ctctagctca
    72721 ggtaagtttt tcagatttta cttgtcccct agtcggcaat acagaagctg ctgtgatgca
    72781 aaaagaggac attgctcagc tcttgacgcg tcaggtcaag gaacccgttc gtttctatga
    72841 aagtattggg gtcatgcaag aagcaggcat aagcaacttt atcgagattg gaccggggaa
    72901 agtcttgtca ggttttgtta aaaaaattga tcaaactgct cacttagctc atgtggaaga
    72961 tcaagcgagt ttagtagcac ttttagaaaa atagactaaa ataagtagaa gttttgaaag
    73021 gaaaaaaatg aaactagaac ataaaaatat ctttattaca ggttcgagtc gtggaattgg
    73081 tcttgccatc gcccacaagt ttgctcaagc aggagccaac attgtcttaa acagtcgtgg
    73141 ggcaatctca gaagaattgc tcgctgagtt ttcaaactat ggtatcaagg tggttcccat
    73201 ttcaggagat gtatcagatt ttgcagacgc taagcgtatg attgatcaag ctattgcaga
    73261 actgggttca gtagatgttt tggtcaacaa tgcagggatt acccaagata ctcttatgct
    73321 caagatgaca gaagcagatt ttgaaaaagt gctcaaggtc aatctgactg gtgcctttaa
    73381 tatgacacaa tcagtcttga aaccgatgat gaaagccaga gaaggtgcta tcattaatat
    73441 gtctagtgtt gttggtttga tggggaatat tggtcaagct aactatgctg cttctaaggc
    73501 tggcttgatt ggctttacca agtctgtggc acgcgaggtc gctagtcgga atatacgagt
    73561 caatgtgatt gctccaggaa tgattgagtc tgatatgaca gctatcttat cagataagat
    73621 taaggaagct acactagctc agattccgat gaaagaattt gggcaggcag agcaggttgc
    73681 agatttgaca gtatttttag caggccaaga ttatctaact ggtcaagtgg ttgccattga
    73741 tggtggctta agtatgtagc gaaagctaga ggtgaaaaga atgaaactaa atcgagtagt
    73801 ggtaacaggt tatggagtaa catctccaat cggaaataca ccagaagaat tttggaatag
    73861 tttagcaact gggaaaatcg gcattggtgg cattacaaaa tttgatcata gtgactttga
    73921 tgtgcataat gcggcagaaa tccaagattt tccgttcgat aaatactttg taaaaaaaga
    73981 taccaaccgt tttgataact attctttata tgccttgtat gcagcccaag aggctgtaaa
    74041 tcatgccaat cttgatgtag aggctcttaa tagggatcgt tttggtgtta tcgttgcatc
    74101 tggtattggt ggaatcaagg aaattgaaga tcaggtactt cgccttcatg aaaaaggacc
    74161 caaacgtgtc aaaccaatga ctcttccaaa agctttacca aatatggctt ctgggaatgt
    74221 agccatgcgt tttggtgcaa acggtgtttg taaatctatc aatactgcct gctcttcatc
    74281 aaatgatgcg attggggatg ccttccgctc cattaagttt ggtttccaag atgtgatgtt
    74341 ggtgggagga acagaagctt ctatcacacc ttttgccatc gctggtttcc aagccttaac
    74401 agctctctct actacagagg atccaactcg tgcttcgatc ccatttgata aggatcgcaa
    74461 tgggtttgtt atgggtgaag gttcagggat gttggttcta gaaagtcttg aacacgctga
    74521 aaaacgtgga gctactatcc tggctgaagt ggttggttac ggaaatactt gtgatgccta
    74581 ccacatgact tctccacatc cagaaggtca gggagctatc aaggccatca aactagcctt
    74641 ggaagaagct gagatttctc cagagcaagt agcctatgtc aatgctcacg gaacgtcaac
    74701 tcctgccaat gaaaaaggag aaagtggtgc tatcgtagct gttcttggta aggaagtacc
    74761 tgtatcatca accaagtctt ttacaggaca tttgctgggg gctgcgggtg cagtagaagc
    74821 tatcgtcacc atcgaagcta tgcgtcataa ctttgtacca atgacagctg ggacaagtga
    74881 agtatcagat tatatcgaag ctaatgtcgt ttatggacaa ggcttggaga aagaaattcc
    74941 atacgctatt tcaaatactt ttggttttgg aggccacaat gcagttcttg ctttcaaacg
    75001 ttgggagaat agataagtat gaatttaaac gatattaaag acttgatgac tcaatttgac
    75061 cagtcaagtt tgagagaatt ttcttataaa aatgggacgg atgagttgca gtttagcaag
    75121 aatgaagcga gacctgtgcc tgaagttgca actcaagtcg ctccagcacc cgttctagca
    75181 acaccgagtc cagtagctcc tacatctgct ccagcagaga ctgtagcaga agaagttcca
    75241 gctccagctg aagcaagtgt ggctagtgag ggaaatcttg tagagagtcc acttgttgga
    75301 gtggtttact tggctgctgg accagataaa cctgccttcg ttacagttgg tgatagtgtc
    75361 aaaaaaggtc aaacattggt aattatcgaa gccatgaaag tcatgaatga aatcccagct
    75421 cctaaggatg gtgtggtaac ggaaattctc gtctctaacg aagaaatggt tgagtttggt
    75481 aaaggattgg tacgtatcaa atgatcgata ttcaaggaat caaagaagct cttccccacc
    75541 gttatcctat gcttctagtg gaccgtgtct tggaagtgag cgaggatacc attgttgcta
    75601 tcaaaaatgt gaccattaac gaacctttct ttaacggcca ctttcctcaa tacccagtta
    75661 tgccaggtgt tctgattatg gaagccttgg cgcaaactgc tggtgtgttg gagttatcaa
    75721 aacctgaaaa taaaggaaaa ctggtctttt acgctggtat ggacaaggtt aagttcaaga
    75781 agcaagttgt accaggcgac caattggtta tgacagcgac ttttgtaaaa cgtcgtggca
    75841 ccatagctgt ggttgaagca aaggctgaag tggatggcaa gcttgcagcc agtggtatcc
    75901 ttacttttgc aattgggaac taaggaggtt ctccatgttt cgaaaaattt taattgccaa
    75961 tcgtggtgaa attgcggttc gtattatccg tgcggcacgt gaattgggga ttgcgacggt
    76021 agcggtttat tcaactgctg ataaggaagc tcttcatacg cttttggcag atgaagcagt
    76081 ttgtattggt cctggcaagg caacagagtc ttatctcaat attaatgcag ttctatcagc
    76141 tgcagtcttg actgaggcag aagctattca ccctggtttt ggatttctca gtgaaaattc
    76201 caaatttgcg accatgtgtg aagaagtagg tatcaagttt atcggtccat ctggtcatgt
    76261 tatggatatg atgggggata agatcaatgc gcgtgctcag atgattaaag caggtgtgcc
    76321 tgttatacca ggttcagatg gagaagtgca taactctgaa gaagctttga ttgttgctga
    76381 aaaaattggc tatcctgtta tgctcaaggc ttcagcaggt ggaggtggta aagggattcg
    76441 taaggttgaa aaaccagatg acctcgtttc tgcctttgaa actgcctcta gtgaggccaa
    76501 ggccaattat ggcaatggtg ccatgtacat agaacgggtt atctatccag ctcggcacat
    76561 tgaggttcaa atcctaggtg atgagcatgg acatgtgatt cacttgggtg agcgggattg
    76621 ttctcttcaa aggaataacc aaaaggtttt ggaagaaagt ccctcgattg caatcggaaa
    76681 aacgctgcgt catgaaatag gtgctgctgc tgttcgagcg gcagagtttg ttggctatga
    76741 gaatgcagga accattgaat ttcttcttga tgaagcaagt agcaatttct atttcatgga
    76801 gatgaatact cgtgttcagg tagaacatcc agtaacagag tttgtttcag gtgttgatat
    76861 cgttaaggaa cagatttgca ttgcggcagg tcagcctttg tctgttaagc aagaagatat
    76921 tgtcctacgc ggtcatgcca tcgagtgtcg tatcaatgca gaaaacccag cctttaactt
    76981 tgctccaagt ccaggtaaga ttactaatct ctatctgcca agtggtggag ttggcttgcg
    77041 cgtggattca gcagtttatc caggttatac cattccgcct tattatgata gtatgattgc
    77101 caaaatcata gtacacggcg aaaatcgttt tgacgccttg atgaaaatgc aacgtgccct
    77161 ctatgaatta gagattgaag gagtgcagac caatgcagat ttccagcttg acctcatttc
    77221 agatcgcaat gtcattgctg gggattatga tacttccttc ttgatggaaa cctttttacc
    77281 taaatatcaa gaaaaagaat aaaatgactt taagagttta aaccgaaaag gggaatcaat
    77341 ggctctattt agtaaaaaag ataagtatat tcgaatcaat cccaatcgtt cggttaggga
    77401 aaaacctcaa gctaagccag aggttccaga tgaattattt tcccagtgtc caggctgtaa
    77461 gcataccatc tatcagaagg atctgggaag tgaacgtatc tgtccgcact gtagctatac
    77521 ctttcgtatt tctgcccaag aacgcttggc tttgacgatt gatatgggaa ccttcaaaga
    77581 attgtttaca gggattgaaa gcaaggatcc cttgcatttc cctggttacc aaaagaaact
    77641 ggcatctatg cgtgaaaaaa caggtctgca tgaagccgtt gtgacaggaa ctgctcttat
    77701 taaaggtcag actgtggctc ttgggattat ggattctaac tttatcatgg cttctatggg
    77761 tacggttgta ggtgaaaaaa tcactcgttt gtttgagtat gcgactgtcg aaaaattgcc
    77821 agttgtccta ttcacagcct ctggtggagc ccgtatgcag gaaggaatca tgagtctcat
    77881 gcagatggct aagatctctg cggcggttaa acgtcattca aatgctggtc tcttttacct
    77941 gaccattttg acagatccaa cgactggtgg tgtgacagct tctttcgcta tggaaggcga
    78001 tatcattctg gctgaaccac agagcttggt tggttttgct gggcgtcgtg tgattgaaaa
    78061 tacggttcgt gaaagcttgc ctgaggattt ccaaaaggca gaattcctat tagaacatgg
    78121 ctttgtggat gctattgtca aaagaagaga cttaccagat acgattgcta gcctagtcag
    78181 attgcatgga gggagtccta gatgaatatt gcaaaaatag tcagagaagc gcgtgagcag
    78241 agtcgcttga caaccttgga ctttgcgaca ggcatttttg atgaatttat ccaattacat
    78301 ggtgaccgtt cttttcgtga tgatggtgca gttgttggtg gtattggttg gcttggagac
    78361 caagctgtaa cagttgttgg tatccaaaaa ggcaagagtt tgcaagacaa cctcaaacgg
    78421 aattttggcc aaccacatcc agaaggctac cgaaaggcac tgcggttgat gaaacaggct
    78481 gagaaatttg gccgtccagt tgtgaccttt attaatacag caggtgctta tcctggtgtc
    78541 ggagcagaag aacgtggtca aggggaagct atcgctcgca atctcatgga aatgagtgac
    78601 ctgaaagttc ctattatcgc cattattatc ggtgaaggtg gttcaggcgg ggctctggct
    78661 ctagctgtcg cggaccgtgt ctggatgctg gaaaattcta tctatgccat tctcagtcca
    78721 gaaggctttg cttccatttt atggaaggac ggtactcgcg ccatggaagc agcagaactg
    78781 atgaaaatca cttcgcatga actgttagaa atggacgtgg tggataaggt gatttctgaa
    78841 ataggacttt ctagtaaaga actgattaag agtgtcaaaa aagaactcca aacggagctg
    78901 gctagacttt cacaaaaacc gctagaagag ttgctggaag aacgctatca acgatttaga
    78961 aaatactaag aatgactaaa tgagactaga aaggtctcat tttttatgga aaaatgtaat
    79021 tcaggtcgaa aaattgccag ttgaggagat gggctataaa atagacaaaa aaagaaatat
    79081 actataaatg tgagcctaca acaatctatt ttaagaaggt acttgcaatg acaggtacaa
    79141 atacatttac agttctttca actgaggact tggagcaaac ttcaggtggt cttgctgttt
    79201 gggaagatgg atatagtaga tggttatatt atagagaatt tgctccctat atgaggcaag
    79261 gggcacttaa ttcttatata gatgcttgga agtacggctt ccgagcaggg taatctttca
    79321 aaaaagtacg atgagaaaca caaaaaaact aagacaattt ggaatatttt tgcttattat
    79381 tttactatct acctatttac cacaaacaat tggattgtat gtgacgatca ttttagggtt
    79441 aggagctgat gtctattctc ttattttaac aatgggatta gtgggaagtt tccttctatt
    79501 aatttggagg ttaaaaaaga aaaagatgct ctttatcttt gagaaaaaga gctggaactg
    79561 gtcatttgtc ttctacttat ttgcaactta tgtggtttat cagattctcg gtaatttttg
    79621 ggcacgctat gctcatttga ttaatcatag gaatattcat gatgagtatt ttaccgtgct
    79681 tttttcaaat ggacaaccaa cctttttatc gactatctta tcttttgtcc tgcctgtaat
    79741 catcggtcct gtttttgagg agactcttga tagagggtat tttatgaata ccttctttcc
    79801 ctagtccaag tactatttgg atgttatcct atctgctatc atctttggga ttagccattt
    79861 gatactatct cacagagatc caattagttt attatattat agtctgattg gtttcttttt
    79921 tgcccttgtt tatcgttcta ccgacaatct gagattaacg attctctgcc atagtttttt
    79981 taactttctc aatcatgcaa aacctatctg gatttttgtt tacaattata tctattatca
    80041 tttttttaga tagtgggagg caaagaaaaa agtgtttgat atctatcaaa cactttttct
    80101 ttttattgtt cttctgttac aaactggctg agcagtccat tgataaaacg ggcagatttt
    80161 tgatcggaga agtcctttgc aagctcgata gcttcattaa cagcaaccag ctgaggagtg
    80221 tcaaatgaag tgatttcaaa gactcccaag cgaaggaggt ttctctccac gagcgttaag
    80281 cgttcaatgg tccaacctgc ttttaaatgc tgagtgattt gcttatctag ttcttccttt
    80341 ttagcttgaa caccagaaac gaggtctatc aaaaaggctg gaagttgtac atccgtatct
    80401 tcacgatcat gagtataggc gaaacgacaa gcagtttcga catccgtacc gaactcaagg
    80461 ctcatgagag cttgaaaagc gcatttacgg agttggcgtc tagattctaa tagtggacta
    80521 gtcattgagg aagtcctcgt caaatagatc tttcaattct ggttttggtg ttttatctgg
    80581 gacgatacct gcaacgtgaa tattgatagc agcgagttct acatcagcca tattacggac
    80641 ggcatctttg acagctttct ggatagcaac cgctacctta ggaactttta ctccgtactc
    80701 aaggtagaga tagatatctg ctgtgagttc ttcgtccacg tttttaagat aaatgccacg
    80761 gccgagtgaa agttttgaaa gggtatcaga cactgatctg tttgaaaaag agtgaacacc
    80821 ctctaccttt gcagtagcga tagcaatgat tttttcaagt acacgtgggg cgataacgat
    80881 ttcgccaagt tgttcttcaa ttcccataga atgacctctt tctagagatt aggcacgaga
    80941 aacgtaagtt ccttctgcag tgttgataac gagtttttgt cctgcttcga tgaagtctgg
    81001 aacgtttacg acaagtccag tttccatcgt tgctggttta ccagaacctg taacagtagc
    81061 acctttgata gatggttgag tttcagcaac tgtcaactca acagtagtag gaacggtgac
    81121 accgatcact tcagttccgt agaattggat tttcacatca gagttttcaa ggatgtaaag
    81181 caattcgttt tcaacattga ctacagggat ttcgtattgg tcgtaagttt ctgtattcat
    81241 gaagtatgct gtgtcatcca ttttgtacaa gtattgagct gggacagtct cgataatagc
    81301 ttgttcaaat ttttcctctg gacggtagct tgtgtcaaat gtagaaccag tacggacatc
    81361 acgcaatttc atacgcatga tcgtgtttcc tttacctggt ttgtggtgac tagcttccaa
    81421 aacgcgaatc aatttgccgt cagctgtttc aaaggtcata ccagctttta atttacttgc
    81481 ttcaatcatg tttttacctc tttaataaat attattactc ttcattttac cataaaatac
    81541 tctggaaata aagccaaaat agttattggg agttggtaga gaagaaaaaa ccaaccttag
    81601 ggctggtttt gttctgtcta gttttctttc aacttcgcca attcctgtgc aagtagttta
    81661 agggcaactt gtgggttggc ttggcctttg gttgccttca taaggaatcc tgtaaaggcc
    81721 ttgtcggcgt tacgtttgcc tgacttgaag tcggcaacag cagcttcgtt atcggcaaag
    81781 acttggtgga tgattgggat caagatagct ggatctgaaa tttgaaccat acctgctttt
    81841 tccacgtatt cacgcgcgcc accgccattt ttagctagat ggacaaagac tttcttggca
    81901 atcttagatg aaatagtacc gtcttcgatg atggcaatca tttcaaccaa gttttctggt
    81961 gtcaattcga tttgttccag tgttttacct tcagcattca agaactgagc gacttcccct
    82021 tggagccagt tagagacttg tttggcatca ccacctaggg caacagcttt ttcaaagaag
    82081 tcagaagtga ctttattagc agtcaactga ctagcatcgt agtctgataa accaaggtca
    82141 gatacataac gcgcacgacg ttcttttgga aactctggca actcagtccg catttcctca
    82201 atccactcgt cagaaatttc aaagaggggt aggtctggtt ctgggaagta gcggtagtca
    82261 gcagcccctt ccttgacacg catgaggatg gttgctttat tcgcttcatc gtaacggcgt
    82321 gtttcttggc ggatttgacc acctgagcga agaatttcag cctggcgttg gacttcgtat
    82381 tcaagcccct tgcgaacgtt tgagaaggag ttgaggttct tcaattcagt cttggtaccg
    82441 aatttctctt gaccataagg acgaagggag atgttggcat ccacacgcat cgaaccttcc
    82501 tccatcttaa cgtcagaaat gccagcatac tggataactt ccttgagtgc tgtcagataa
    82561 gcataggcct cctctggcga acgcatatcg gcttcagata caatctcaat caaaggtacc
    82621 ccttggcggt taaggtcaac gtaagagtag ccgtctgtac cgtgggtgtt tttaccagcg
    82681 tcttcctcta agtgggcgcg ttcgatacca attttcttgg tcgtaccgtc ttctagctcg
    82741 acttcaatcc agccgttata accgattggc tcatcaaact gagaaatttg gtaggctttg
    82801 ggattatcag ggtagaagta gttcttgcgg tcaaagtgca tttttttgtg gatgtccatg
    82861 ttgagggcaa gagcagcctt gataccggca tcaacaaccc ctttattgag aactggcaga
    82921 actcctggga aagaccagtc aatcacgtta gtgttggcat tttgatcatt tccgaagtgg
    82981 gcagaagtag gtgagaagat ttttgaattg gtgttgagct ctacgtggac ttcaagtccg
    83041 atgactgttt caaagttcat tagttgtcac ctccaaaaat cacgggttgt tgtttgtggt
    83101 agtctgttgt tgcttcaaaa gcagcagcag cttggtaaat ggtttcctca gagtacttgg
    83161 gaccaatcaa ttggagtccg acaggtagac cttgagagaa tccagcagga atcgaaattc
    83221 caggcagtcc tgccaagttt acaggtatgg tcaataggtc ggctaagtac atggcaactg
    83281 ggtcatggtt gagagaatcc aagtcatagg caacacttgg agcagttgga cccaaaatca
    83341 aatcgtaatc cgcgaagact ttttcgaaat cttgaatgat gagggtacgg acttgaccag
    83401 cctttttgta gtaggcatca tagtaacctg atgaaagact gaaagtaccc agcatgatac
    83461 gacgttttac ctcttcacca aaaccttggc ttcggctgtt tacatagatt tcatcaaggt
    83521 tggttgcatc ttctgcgcga tagccgtaac ggataccgtc gaagcgttgc aagtttgatg
    83581 aagcttctga tgaagcgatg atgtagtata cggcaactcc gtatttagag tgaggaaggc
    83641 tgacttcttc gacaatagca cccaattttt caaagtgttt agcggcattt agaatggttt
    83701 ccttaacctc tgggttaatt ccttcaccga ggtattcctt aggcaaagcg attttcatac
    83761 ccttgatgtc ttggccgatt tttgaagtaa agtcggcgat gcggacagga gcagaagtag
    83821 agtctttagc atcttcgctg gcaatagcgt tgagcaagag ggcattttcc ttaacagtag
    83881 gagcaaaagg tccaatctgg tctaatgagc taccaaaggc aatgagaccg aaacgtgaaa
    83941 ctgttccgta ggttggtttg agaccaacga ttccgttgaa ggcagcaggt tggcggatgg
    84001 aaccaccagt atcagaacca agtgacaagc gaacttgtcc tgaggctaca gctgcggcag
    84061 aaccacttga tgacccacca ggaaccttgc tgtggtccca agcgttttta gttgctccgt
    84121 agtgtgaagt ttcacctgaa ccacccatag caaattcgtc catgttggtc tttccaacga
    84181 caatcatgcc tttggttttt gcattggcaa cagctgtcgc atcaaagatt ggctcatagt
    84241 tgtagagcat ttttgaggca gcagttgtga gaataccgtc tgtagagatg ttatccttaa
    84301 cagcaagtgg aattcctgaa aggacattgt cagcatcaat tccagcttca tcaatggctt
    84361 tagcttgaac aagagcttgc tcctcagcga tggtgacaaa tgaattgagg gcttcctcac
    84421 gagacttgat attttcaagt gttgtttggg tcaattctgt tgcagaaatt tccttagaga
    84481 caaggagatt gtgcaactct tcaatagttt tattgttaaa agtcattagg catctcctcc
    84541 atcgtctagg atagctggca ccttgatata gtagttgtct ttttcaggta cgtttttaaa
    84601 caagcgatca cggtctgttc cttcttcggc cacatcaggg cggagtacag tcttgcggtc
    84661 agccatagtc gtagtaggtg cgacaccagt tgtgtcaact tcgcccagca attcaaccat
    84721 gtcaacaatc ttagacaagg tggtcgcaaa ggcagcagtt tcttcttcag agaatcttaa
    84781 ttttgaaaga ttggcaacgt gtgttacctc ttcttgcgta attttcatct tgcatccttt
    84841 cgtgaaatga tgatttttag tctgttctat tttaccatat tttcctataa ataagggagg
    84901 gggaagtgaa aagaaataga aattgaaaaa aatgctaaaa tccgatataa tggagtgttg
    84961 aaaggaatgg taaaatccaa tgtaaaaatc attctcagct attgaaacaa gaaaaataga
    85021 gaatcaaaga aagagaactt atgaatattc aagaagaaat taagaaacgt cgtacctttg
    85081 ccattatctc ccacccggac gcggggaaaa caaccatcac tgagcagtta ctctactttg
    85141 ggggtgagat tcgtgaggct ggtacggtaa aagggaagaa aacagggact tttgctaaat
    85201 ctgactggat ggatatcgag aagcaacgtg ggatttctgt tacttcatct gttatgcaat
    85261 ttgactacga cggcaagcgc gtgaatatct tagacacgcc agggcacgag gacttctcag
    85321 aagataccta tcgtaccttg atggcggtgg atgctgcggt catggtcgtg gactctgcca
    85381 aggggatcga ggctcaaacc aagaaattgt ttgaggttgt gaaacatcgt ggcattccag
    85441 tctttacctt tatgaacaag ctggaccgtg acggtcgtga gcctttggaa ctcttgcaag
    85501 aattggaaga aatcttgggc attgctagct accctatgaa ctggcctatc gggatgggga
    85561 aagcctttga gggcttgtat gacctctata accaacgttt agaactttat aaaggggatg
    85621 agcgttttgc tagcctagaa gatggagaca aactttttgg tagcaatcct ttctacgagc
    85681 aagtcaagga tgacattgag cttttaaatg aagctgggaa tgagttttca gaggaagcta
    85741 ttctggctgg agaattgacg cctgtctttt tcggttcagc cctgacaaac tttggtgtgc
    85801 agaccttcct tgaaatcttc ctcaagtttg ctccagaacc acatggtcac aagaaaacag
    85861 atggtgaaat tgtggatcct tatgacaagg atttctcagg ctttgtcttt aaaatccaag
    85921 ccaacatgga tcctcgtcac cgtgaccgta ttgcctttgt ccgtatcgta tcaggcgaat
    85981 ttgagcgcgg catgagtgtc aatctccctc gtactggtaa gggggctaaa ctatctaatg
    86041 ttacccagtt tatggcggag agtcgtgaga atgtgaccaa tgccgtggca ggtgatatta
    86101 tcggggttta cgataccggt acttatcagg ttggggatac cttgacggtt ggaaaaaaca
    86161 agtttgaatt tgaaccattg ccaaccttta ctcctgaaat tttcatgaaa gtttctgcta
    86221 agaatgttat gaagcaaaaa tccttccaca aggggattga gcaattggtg caagaaggag
    86281 ccgttcagct ttataagaat taccaaacag gtgagtacat gctgggagct gttggtcaac
    86341 tccagtttga agtctttaaa caccgtatgg aaggcgaata caatgcggaa gtggtcatga
    86401 gcccaatggg taaaaagacc gttcgttgga tcaagcctga ggacttggat gaacggatgt
    86461 cgtcaagtcg caatatctta gccaaagacc gttttgacca accagtcttt ctctttgaaa
    86521 atgactttgc cctccgctgg tttgcggaca agtatccaga cgtagagtta gaggagaaga
    86581 tgtgactcag taccaacaat tggaactaaa gttccaaatt gttggacgct agtcgctatt
    86641 tggcgaacta gctaactgcc tcactaacta cgtttggcaa atagaatcga tttgccaaac
    86701 tccgtgtcgt aatctaataa tcggtaaccg ctatggcggc ttacctaaac gcttcactag
    86761 gaaaaatcca cgaatggtat tgatttgtgg atttttccgt cgtagcagaa agtaggtagc
    86821 ctagctaact gccttactaa ctacgtttgg caaatgaaat cgatttgtaa aactctgtgt
    86881 cgtaatgtaa aaattgtaaa ccgtaatggg acttcatcta aaatctccac tggtatggtt
    86941 ttacgaacga ataggcgaaa ataatggtta cgtagaaaca tatgatggga ataaaaagaa
    87001 atgagataaa aagtgaaaga agagaaaaaa gcgattgtct taggtgcaga taatgcttat
    87061 atggataaag ttgaaacaac aataaaatct ctttgtgttc atcattataa tcttaagttt
    87121 tatgttttta atgatgacct tccgcgagaa tggttccaat taatggaaaa aagactagag
    87181 actttgaata gtgagattgt gaatgtttag attgacagta gtattctgaa aggttatcgt
    87241 ctcccctttg agggactttc atatgcggct tttttaggta ttttattcca aagtatgtaa
    87301 gcgagtctcg tgtactgtat ttggattcag atattgttgt aagaaaatcg atagatgagc
    87361 tgtgggattt ggacttgacg gctataccct tagctgcagt tagagatgat ttttatacac
    87421 ataattttaa ttctggtgtt ctgttaatca acaatggcat gtggagagca gaaaatgtca
    87481 cgcaagacct gatttaagac acaaataaaa aatcttccaa ttcccttgca aaaaacaaga
    87541 aagtgtgata acatagtacg gtatgtggtg ctagcacatc cgctatatta gatctaatag
    87601 gaggaaaaca caatggctaa agtatgttac tttacaggtc gtaagactgt atcaggaaac
    87661 aaccgttcac acgcgatgaa ccaaacaaaa cgtgccgtaa aaccaaacct tcaaaaagtt
    87721 actgttctta tcgatggtaa acctaaaaaa gtttgggctt cagctcgtgc tttgaaatca
    87781 ggtaaagttg aacgcgttta ataataaaag caaaggagac cttagggtct tttttctttt
    87841 attgtgggta taacatcgtt tgaaaaatag agtaaatatc cgctgataca tcattctgct
    87901 tttacacttg ggctgaaata tgataaaata gagtatcaac tagttgaggt aaaaaggatg
    87961 actgtaaaaa ttaatacaaa agatggtcaa atcgaactaa cagatgaagt gattgcaacc
    88021 gtcgtaggtg gagcagcaac tgagattttt ggtgtggtcg gtatggctag taaaaatgcc
    88081 ctcaaagata atttccaagc cctgctaggt aaggaaaatt attctaaagg tgtcgtcgta
    88141 aaggcagccg aagatggcag tattgcagtt gatgtatata ccgtgttaag ctacggaaca
    88201 aagattagtg aagtgtcaaa aaacattcaa gagcgtgttg cctttagctt ggaaaaccag
    88261 cttggaatta ctgctcagac tgtaaatgtc tacattcaaa atatcaaagt tgtaggagaa
    88321 taaccgtgtc aaaaattact actagcttat ttcaagaaat ggtgcaggct gcatcaactc
    88381 gcttgaataa gcaagctgaa tatgtcaatt cattaaacgt ctttccagtt ccagatggag
    88441 atactgggac aaatatggga atgaccattg aaaatggtgc taaagaagtt gcagacaagc
    88501 cagcttctac agttggagaa gtagcgagca ttcttgccaa agggcttttg atgggtgcgc
    88561 gtgggaactc aggagtgatt acgtctcagc ttttccgtgg attttcccaa gctatcaagg
    88621 ataaagacga gttaacaggt caagacttgg ctctggcctt ccaatcaggt gtggaagttg
    88681 cctataaggc agtgatgaaa cctgttgaag gaacgatttt gacagtttct cgtggagctg
    88741 ctatcggtgc taagaaaaaa gctgagcaaa cagatgacac tgttgaagtc atgcgcgcag
    88801 ccttggaagg tgctaaaaca gctctagcta aaacaccaga catgcttcca gtattgaaag
    88861 aagttggcgt tgtggactca ggtggtcaag gattggtctt catctacgaa ggtttccttt
    88921 cagcccttac tggcgaatat attgcatctg aggactttgt agcgactcct gccaacatga
    88981 gtgagatgat caatgtagag catcataagt ctgtagctgg tcacgtagcg actgaggaca
    89041 tcacgtttgg ttactgtact gaaatcatgg tagctcttaa gcaaggtcca acctatgcta
    89101 aagattttga ctacgatgaa ttccgtaact acttggatga gcttggggat tctctcctcg
    89161 ttgttaacga tgatgaaatt gtcaaagtcc atgttcatac agaagatcca ggacttgtta
    89221 tgcaagaagg tctcaaatat ggtagcttgg tcaaggtaaa agttgacaat atgcgtaacc
    89281 aacacgaagc acaggttgag aaagaagcta ctcaagttat caagtcggct gaagaaaaag
    89341 agtatgcttt gattgctgtg gtggctggta aaggtctagc agatatcttc tgttctcaag
    89401 gcgtggatta tgttatcgaa ggcggtcaaa ccatgaaccc ttcaacagaa gactttatca
    89461 aggctgttga acaggtcaat gcccgtaaca tcatcttctt gccaaacaac aagaacatct
    89521 tcatggcagc tcaatctgcg gcagaagttt tggagcaacc agcagtagtg gtagaggctc
    89581 gcactcttcc tcaaggtatg acaagtcttc ttgcctttga tccaagcaag tccattgaag
    89641 aaaaccaaga gcgtatgaca gctgctctta gcgatgtcgt tagcggaagc gtcacaacag
    89701 ccgtgcgtga tacaacgatc gatggcttag aaatccatga aaacgataat ctaggtatgg
    89761 tggatggaaa aattcttgtg tcaaaccctg atatgcacca aacattgact gaaaccttga
    89821 aacatatgtt ggatgaagat agtgaaatcg taaccttcta tgtcggtgaa gacggaagcg
    89881 aagaacttgc caatgaaatc gctcaagaaa tcgtagaaga attcgaagac gttgaagtcg
    89941 agattcacca aggtcaacaa cctgtttacc catacctatt tagtgtggaa taagattaat
    90001 gaaggactga gaaatcagtt cttttttctt ttttagtaaa tgaaatcggt atctttttaa
    90061 taaaaacaaa aataacattc ataaataaac gttaaaatag aaaattcaga aaatttcttc
    90121 ttttatcttg aaaaattttg aaaaaatggt atgatagtaa caagttattt ttaagaggaa
    90181 agaaagggga acaatggaga aaatcagttt agaatctcct aagacggggt cggacctagt
    90241 tttggaaaca cttcgtgatt taggagttga taccatcttt ggttatcctg gtggtgcggt
    90301 tttgcctttt tatgatgcga tatataattt taaaggcatt cgccacattc tagggcgcca
    90361 tgagcaaggt tgtttgcatg aagctgaagg ttatgccaaa tcaactggaa agttgggtgt
    90421 tgccgtcgtc actagtggac caggagcaac aaatgccatt acagggattg cggatgctat
    90481 gagcgatagc gttccccttt tggtctttac aggtcaggtg gcgcgagcag ggattgggaa
    90541 ggatgccttt caggaggcag acatcgtagg aattaccatg ccaatcacta agtacaatta
    90601 ccaagttcgt gagacagctg atattccgcg tatcattacg gaagctgtcc atatcgcaac
    90661 tacaggccgt ccagggccag ttgtaattga cctaccaaaa gacatatctg ctttagaaac
    90721 agacttcatt tattcaccag aagtgaattt accaagttat cagccgactc ttgagccgaa
    90781 tgatatgcaa atcaagaaaa tcttgaagca attgtccaag gctaaaaagc cagtcttgtt
    90841 agctggtggt ggaattagtt atgctgaggc tgctacggaa ctaaatgaat ttgcagaacg
    90901 ctatcaaatt ccagtggtaa ccagtctttt gggacaagga acgattgcaa cgagtcaccc
    90961 actctttctt ggaatgggag gcatgcacgg gtcattcgca gcaaatattg ccatgacgga
    91021 agcggacttt atgattagta ttggttctcg tttcgatgac cgtttgacgg ggaatcctaa
    91081 gactttcgct aagaatgcta aggttgccca cattgatatt gacccagctg agattggcaa
    91141 gattatcagt gcagacattc ctgtagttgg agatgctaag aaggccttgc aaatgttgct
    91201 agcagaacca acagttcaca acaatactga aaagtggatt gagaaagtca ctaaagacaa
    91261 gaatcgtgtt cgttcttatg acaagaaaga gcgtgtggtt caaccgcaag cagttattga
    91321 acgaattggt gaattgacga atggagatgc cattgtggta acagacgttg gtcaacacca
    91381 aatgtggaca gctcagtatt atccctacca aaatgagcgt cagttagtga cttcaggtgg
    91441 tttgggaaca atgggctttg gaattccagc agcaatcggt gctaaaattg ctaacccaga
    91501 taaggaagta gtcttgtttg ttggggatgg tggtttccaa atgaccaacc aggagttggc
    91561 tattttgaat atttacaagg tgccaatcaa ggtggttatg ctgaacaatc attcacttgg
    91621 aatggttcgc cagtggcagg aatccttcta tgaaggcaga acatcagagt cggtctttga
    91681 tacccttcct gatttccaat tgatggcgca ggcttatggt attaaaaact ataagtttga
    91741 caatcctgag accttggctc aagaccttga agtcatcact gaggatgttc ctatgctaat
    91801 tgaggtagat atttctcgta aggaacaggt gttaccaatg gtaccggctg gtaagagtaa
    91861 tcatgagatg ttgggggtgc agttccatgc gtagaatgtt aacagcaaaa ctacaaaatc
    91921 gttcaggagt cctcaatcgc tttacaggtg tcctatctcg tcgtcaggtt aatattgaaa
    91981 gcatctctgt tggagcaaca gaagatccga atgtatcgcg tatcactatt attattgatg
    92041 ttgcttctca tgatgaagtg gagcaaatca tcaaacagct caatcgtcag attgatgtga
    92101 ttcgcattcg agatattaca gacaagcctc atttggagcg cgaggtgatt ttggttaaga
    92161 tgtcagcgcc agctgagaag agagctgaga ttttagcgat tattcaacct ttccgtgcaa
    92221 cagtggtaga cgtagcgcca agctcgatta ccattcagat gacgggaaat gcagaaaaga
    92281 gcgaagccct attgcgagtc attcgcccat acggtattcg caatattgct cgaacgggtg
    92341 caactggatt tacccgcgat taaaaatcca acttaaattt attaaaccag cctaaaaggc
    92401 aataaataat agaaaagaga gaaaagctat gacagttcaa atggaatatg aaaaagatgt
    92461 taaagtagca gcacttgacg gtaaaaaaat cgccgttatc ggttatggtt cacaaggaca
    92521 tgcgcatgct caaaacttgc gtgattcagg tcgtgacgtt attatcggtg tacgtccagg
    92581 taaatctttt gataaagcaa aagaagatgg atttgatact tacacagtag tagaagctac
    92641 taagttggct gatgttatca tgatcttggc gccagacgaa attcaacaag aattgtacga
    92701 agcagaaatc gctccaaact tggaagctgg aaacgcagtt ggatttgccc atggtttcaa
    92761 catccacttt gaatttatca aagttcctgc ggatgtagat gtcttcatgt gtgctcctaa
    92821 aggaccggga cacttggtac gtcgtactta cgaagaagga tttggtgttc cagctcttta
    92881 tgcagtatac caagatgcaa caggaaatgc taaaaacatt gctatggact ggtgtaaagg
    92941 tgttggagcg gctcgtgtag gtcttcttga aacaacttac aaagaagaaa ctgaagaaga
    93001 tttgtttggt gaacaagctg tactttgtgg tggtttgact gcccttatcg aagcaggttt
    93061 cgaagtcttg acagaagcag gttacgctcc agaattggct tactttgaag ttcttcacga
    93121 aatgaaattg atcgttgact tgatctacga aggtggattc aagaaaatgc gtcaatctat
    93181 ttcaaacact gctgaatacg gtgactatgt atcaggtcca cgtgtaatca ctgaacaagt
    93241 taaagaaaat atgaaggctg tcttggcaga catccaaaat ggtaaatttg caaatgactt
    93301 tgtaaatgac tataaagctg gacgtccaaa attgactgct taccgtgaac aagcagctaa
    93361 ccttgaaatt gaaaaagttg gtgcagaatt gcgtaaagca atgccatttg ttggtaaaaa
    93421 cgacgatgat gcattcaaaa tctataacta attagaaata tatagcgctg gagatgattt
    93481 tatgaaaaag attatgagaa aaattgcatc gttattattg gttctagttg tataatgtaa
    93541 ttacaccgtc ggtaatagtg ctagcagacc aaaataaagc agattggtcg tatgatgaaa
    93601 atgctgtaat taacatttat gatgatgcta attttgaaga tggtaggttg catatgacct
    93661 ttgaacaatt cttcaaattg gcacaaatag ctagagaaga aggtcttgaa attcattctc
    93721 cgtttgagag agctggtgcg actaaatctg ctcgttatat agcgaaatgg attttgagaa
    93781 ataaaaaaca ttaacaaata tagttggtaa atcattagga cctaaatcag ctgttagatt
    93841 cggagaagct ttatcctata ttgaaggtcc tcttcgcaga ataaatgaga cgatagatgg
    93901 cggtttatat caaatagagc aaattattgc atctggattg aaagaatcgg gtttaaatga
    93961 ctggactgcg aaaactttag cttcagctat tcgtgggata ttagatgtac ttatttaggg
    94021 gttgaaatca tatgaatatt accaatttgt tttctatcaa gacaggatgt gatgaaactg
    94081 ataggcaact gcaaaaacta ttttttcagt tggatttaca attgggagaa ttgacagatc
    94141 aactaagaaa attagattct aattttgttc ctcgtagtca atttgtagac acgttggatt
    94201 tgaatgatgt agaatataaa gaaattttaa actattttat cttccatcgt aatgatagtg
    94261 aagaaagttt ggtagaatgg ttatatgatt ggatttccac aaatcgttat gaacttccta
    94321 aagagttttc gattcgtatg gctcataaat accatgaaag tgttactgaa gttttcggag
    94381 atgaataact aaaaaacagt cattagtgac tgttttttat agaaaaagag gttttatatg
    94441 ttaagttcaa aagatataat caaggctcac aaggtcttga acggtgtggt tgtgaatact
    94501 ccactggatt acgatcatta tttatcggag aagtatggtg ctaagattta tttgaaaaaa
    94561 gaaaatgccc agcgtgttcg ctcctttaaa attcgtggtg cctattatgc catttcccag
    94621 ctcagcaagg aagaacgtga acgtggggta gtctgcgctt ctgcgggaaa tcatgcgcag
    94681 ggagtagcct atacttgtaa tgaaatgaaa attcctgcta ctatctttat gcctattact
    94741 acgccacaac aaaagattgg tcaggttcgc ttttttggtg gggattttgt aactattaaa
    94801 ctagttggag atacctttga tgcctcagcc aaagcagctc aagaatttac agtctctgaa
    94861 aatcgtacct ttattgatcc ttttgatgat gctcatgttc aagcaggtca aggaacagtt
    94921 gcttatgaga ttttagaaga agctcgaaaa gaatcgattg attttgatgc tgtcttggtt
    94981 cctgttggtg gtggcggtct cattgccggg gtttctacct atatcaagga aacaagtcca
    95041 gagattgagg ttatcggagt agaggcgaat ggagcgcgtt ccatgaaagc tgcctttgag
    95101 gctggaggtc cagtcaaact caaggaaatt gataaatttg cggatgggat tgctgtgcaa
    95161 aaggtaggtc agttgaccta tgaagcaact cgtcaacata ttcaaacttt ggtaggtgtc
    95221 gatgagggat tgatttctga aaccttgatt gacctttact ctaagcaagg gatagtcgca
    95281 gaacctgctg gagcggctag tatcgcctct ttagaggttt tagctgaata tattaagggg
    95341 aaaaccattt gttgtatcat ttctggagga aataatgata tcaaccgtat gccagaaatg
    95401 gaagagcgtg ccttgattta tgatggtatc aaacattact ttgtggtcaa tttcccacag
    95461 cgtccaggag ctttgcgtga gtttgtaaat gatatcctgg ggccaaatga tgatatcaca
    95521 cgttttgagt atatcaaacg agctagcaag ggaacaggcc cagtattgat tgggatcgct
    95581 ttggcagata agcatgatta tgcaggtttg atccgtagaa tggaaggttt tgatccagct
    95641 tatattaact taaatggtaa tgaaacgctt tataatatgc ttgtctgagg actaataaaa
    95701 aaatatcata ttatttgtac aactgatgta tatgtgctat aatgaagatg aagaaagggg
    95761 acgattccta tggttttaga aaacttatcg tgcaattctt acttctgttc attatagcac
    95821 ttatgatgtt tggctcagat ttccatcctt cattttgatt tcctatctat tgacaagcat
    95881 agtcatactg tctttaatac tcttcgaaaa tctcttcaaa ccacgttagc tctatctgaa
    95941 acctcaaaac agtgttttga gcaatttgcg gctagcttcc tagtttgctc tttgattttc
    96001 attgagtata aggtatgatt tgatttcttt ttgttgacaa atataccata ttaaaaagat
    96061 atataagtaa ttaactgagc ttatctgtct tgtcatctct attaaggatg gtttagataa
    96121 tcgggtgtct gcttctaggc tagcacctca atatccaaag gagtgatgaa tttgaaggat
    96181 ataaggaata cctatctctc agatgattta ttgaggaaga aagataggag tttttgagct
    96241 agagaaggct tggatttcta aaggttagaa ctatcatctt cagttcttaa atcgaagaaa
    96301 taagctatct tacggaaata gagaagcatt ttttaagaac ttgaataatt tcgcacctta
    96361 agagggtaat aatacagtat ttttattagc aaatatttat ggtgtagagg ctagcaaaac
    96421 ctatatatta tcggatttaa aaaggaagta agaaaattct gaactaatta ttttcgttga
    96481 atatatgttt ttttattgac aaaagtagta aaaacgtata caatcaaata ttataaagaa
    96541 gaaaatagga gaaaaacatg gctaagtcaa actttgaaaa agtagaatca gttgttggct
    96601 gggttcgtga taagaaaatc acaggctacc gtatctctaa agaaacgaat gcgcgtgaaa
    96661 tgtctatcat tgctctggcg cagggtcgtg caaaagtaaa aaatatttca tttgaaacag
    96721 ccctaggctt aattgatttc tatgaaaaaa atcatgaaaa atttgaagat taatctttgg
    96781 ataacggtgg attcttgacc ttcaagtagt agagatagag aatctgcctt ttcattttga
    96841 ggacagcaaa aagactgcac ggttgatgca gccttttctt tttattt
//
LOCUS       DBERPV010000003        95583 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.03, whole genome shotgun sequence.
ACCESSION   DBERPV010000003 DBERPV010000000
VERSION     DBERPV010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 95583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 95583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..95583
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.03"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..134
                     /locus_tag="ACL8C7_000280"
                     /pseudo
     CDS             1..134
                     /locus_tag="ACL8C7_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            137..1148
                     /locus_tag="ACL8C7_000281"
                     /pseudo
     CDS             137..1148
                     /locus_tag="ACL8C7_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259617.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0004601 - peroxidase activity [Evidence
                     IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Dyp-type peroxidase"
     gene            1123..1701
                     /locus_tag="ACL8C7_000282"
     CDS             1123..1701
                     /locus_tag="ACL8C7_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HGS1394550.1"
                     /translation="MVRNYWKAKSWLLVLALSFLILSPAGAQESLSFFFVKITDASKA
                     VKNGGQTETQKLVTKMASDFERVENKDSEVGKIVKEKLALSGDITEAKLTEISSALLA
                     FEKEQNPVDLDAEKEKLVNRLSPRFETLEQAIAFKDLEKVREAFKKMNSTWTINESVV
                     RYNSIAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(1758..2000)
                     /locus_tag="ACL8C7_000283"
     CDS             complement(1758..2000)
                     /locus_tag="ACL8C7_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HGS1394551.1"
                     /translation="MKKDIHPEYRSVVFMDTTTGYQFLSGSTKRSNETVEFEGETYPL
                     IRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(2096..3031)
                     /locus_tag="ACL8C7_000284"
     CDS             complement(2096..3031)
                     /locus_tag="ACL8C7_000284"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HGS1394552.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            3135..3578
                     /locus_tag="ACL8C7_000285"
     CDS             3135..3578
                     /locus_tag="ACL8C7_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HGS1394553.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVG"
     gene            3694..3960
                     /locus_tag="ACL8C7_000286"
     CDS             3694..3960
                     /locus_tag="ACL8C7_000286"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HGS1394554.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREAVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            3957..4331
                     /gene="crcB"
                     /locus_tag="ACL8C7_000287"
     CDS             3957..4331
                     /gene="crcB"
                     /locus_tag="ACL8C7_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HGS1394555.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTLLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            4325..4654
                     /gene="crcB"
                     /locus_tag="ACL8C7_000288"
     CDS             4325..4654
                     /gene="crcB"
                     /locus_tag="ACL8C7_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HGS1394556.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            4773..5120
                     /gene="rplS"
                     /locus_tag="ACL8C7_000289"
     CDS             4773..5120
                     /gene="rplS"
                     /locus_tag="ACL8C7_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HGS1394557.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            5163..5234
                     /locus_tag="ACL8C7_000290"
     tRNA            5163..5234
                     /locus_tag="ACL8C7_000290"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5196..5198,aa:Arg,seq:cct)
     gene            complement(5406..6404)
                     /locus_tag="ACL8C7_000291"
     CDS             complement(5406..6404)
                     /locus_tag="ACL8C7_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005634 - nucleus [Evidence IEA];
                     GO_function: GO:0003712 - transcription coregulator
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HGS1394558.1"
                     /translation="MNFFSKLFNLKQNNHNRDTNSDCNNFYLNKLECGLTPGQLILID
                     WTQKTGRNYNFPRYFKYSLQIDPESTHNQLYKLGYFTKNKTLSYLKVVELKTILSKHN
                     LPTSGKKAELITRIINNINVDKLDIPFEFKLTKEAQNLIIEHSDYIKAYYDKDITMED
                     YCKEKNNISFKATFGDIKWSILNKQAHRNTVSGDFGCLSNTRKAQGRHLEQEGNIKHS
                     LIYYIESLIITSSGLENNFSATDYPVYYPDSIPDYSLKHIQTLMESLSDDDYDFAFDE
                     ALFRFSILNANHFLSKEDIDYLRVNLPCSTAEEINNYLKKYECYSPLNNLELDDVE"
     gene            complement(6447..7253)
                     /gene="yidA"
                     /locus_tag="ACL8C7_000292"
     CDS             complement(6447..7253)
                     /gene="yidA"
                     /locus_tag="ACL8C7_000292"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HGS1394559.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGTYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKSNDESGVAHAIRTWVL"
     gene            complement(7266..8570)
                     /locus_tag="ACL8C7_000293"
     CDS             complement(7266..8570)
                     /locus_tag="ACL8C7_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HGS1394560.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMIAALLHDLGHGAYS
                     HTFEHLFDTDHEAITQEIIQSPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPKDKDFFARTSPHLLPFFEKNVTLSD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLYLIENDHFTPNKN"
     gene            8642..9019
                     /locus_tag="ACL8C7_000294"
     CDS             8642..9019
                     /locus_tag="ACL8C7_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HGS1394561.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKNSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            9110..9442
                     /locus_tag="ACL8C7_000295"
     CDS             9110..9442
                     /locus_tag="ACL8C7_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HGS1394562.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            9454..11025
                     /gene="ffh"
                     /locus_tag="ACL8C7_000296"
     CDS             9454..11025
                     /gene="ffh"
                     /locus_tag="ACL8C7_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002902912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HGS1394563.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(11220..12503)
                     /locus_tag="ACL8C7_000297"
     CDS             complement(11220..12503)
                     /locus_tag="ACL8C7_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HGS1394564.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(12757..13470)
                     /gene="rsmG"
                     /locus_tag="ACL8C7_000298"
     CDS             complement(12757..13470)
                     /gene="rsmG"
                     /locus_tag="ACL8C7_000298"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HGS1394565.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            13564..14124
                     /locus_tag="ACL8C7_000299"
     CDS             13564..14124
                     /locus_tag="ACL8C7_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HGS1394566.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            14126..15025
                     /gene="htpX"
                     /locus_tag="ACL8C7_000300"
     CDS             14126..15025
                     /gene="htpX"
                     /locus_tag="ACL8C7_000300"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HGS1394567.1"
                     /translation="MLFNQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSGMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(15069..16628)
                     /locus_tag="ACL8C7_000301"
     CDS             complement(15069..16628)
                     /locus_tag="ACL8C7_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS1394568.1"
                     /translation="MYYRHSRKGNSMIKINHLTITQNKDLRDLVSDLTMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQSLAYIPQKVPEDLKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMKKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLQRLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(16867..17184)
                     /locus_tag="ACL8C7_000302"
     CDS             complement(16867..17184)
                     /locus_tag="ACL8C7_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HGS1394569.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EKLNNSILIDLEKFYQPTSPLIGLGSLKLNDQARTAWRNYDKIHYEHVKHVLSLYGPV
                     FGF"
     gene            17363..17905
                     /locus_tag="ACL8C7_000303"
     CDS             17363..17905
                     /locus_tag="ACL8C7_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HGS1394570.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQKA
                     VKKEENSPFAGLQGLFDGDE"
     gene            17905..18534
                     /gene="nth"
                     /locus_tag="ACL8C7_000304"
     CDS             17905..18534
                     /gene="nth"
                     /locus_tag="ACL8C7_000304"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HGS1394571.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            18745..19266
                     /gene="pyrR"
                     /locus_tag="ACL8C7_000305"
     CDS             18745..19266
                     /gene="pyrR"
                     /locus_tag="ACL8C7_000305"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HGS1394572.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            19285..20208
                     /locus_tag="ACL8C7_000306"
     CDS             19285..20208
                     /locus_tag="ACL8C7_000306"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HGS1394573.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGSELFFAGPEEWRSQEFADYGKFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            20258..21337
                     /locus_tag="ACL8C7_000307"
     CDS             20258..21337
                     /locus_tag="ACL8C7_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HGS1394574.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            21650..24826
                     /gene="carB"
                     /locus_tag="ACL8C7_000308"
     CDS             21650..24826
                     /gene="carB"
                     /locus_tag="ACL8C7_000308"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HGS1394575.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(25101..25910)
                     /locus_tag="ACL8C7_000309"
     CDS             complement(25101..25910)
                     /locus_tag="ACL8C7_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGS1394576.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKYDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYITPPSKEMQEWYSHSIKAYRKN"
     gene            complement(25912..26715)
                     /locus_tag="ACL8C7_000310"
     CDS             complement(25912..26715)
                     /locus_tag="ACL8C7_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGS1394577.1"
                     /translation="MKQLTIEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(26725..28212)
                     /gene="tacF"
                     /locus_tag="ACL8C7_000311"
     CDS             complement(26725..28212)
                     /gene="tacF"
                     /locus_tag="ACL8C7_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HGS1394578.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFIDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVVPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            28548..29255
                     /locus_tag="ACL8C7_000312"
     CDS             28548..29255
                     /locus_tag="ACL8C7_000312"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050518 - 2-C-methyl-D-erythritol
                     4-phosphate cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HGS1394579.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            29260..30282
                     /locus_tag="ACL8C7_000313"
     CDS             29260..30282
                     /locus_tag="ACL8C7_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribitol-5-phosphate dehydrogenase"
                     /protein_id="HGS1394580.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            30299..31168
                     /gene="licA"
                     /locus_tag="ACL8C7_000314"
     CDS             30299..31168
                     /gene="licA"
                     /locus_tag="ACL8C7_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HGS1394581.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            31158..32036
                     /locus_tag="ACL8C7_000315"
     CDS             31158..32036
                     /locus_tag="ACL8C7_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGS1394582.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            32048..32737
                     /locus_tag="ACL8C7_000316"
     CDS             32048..32737
                     /locus_tag="ACL8C7_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="HGS1394583.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            32833..33681
                     /gene="dprA"
                     /locus_tag="ACL8C7_000317"
     CDS             32833..33681
                     /gene="dprA"
                     /locus_tag="ACL8C7_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HGS1394584.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLLTSGQDV
                     LAEFEF"
     gene            34565..35608
                     /locus_tag="ACL8C7_000318"
     CDS             34565..35608
                     /locus_tag="ACL8C7_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HGS1394585.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEHFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            35775..37862
                     /gene="topA"
                     /locus_tag="ACL8C7_000319"
     CDS             35775..37862
                     /gene="topA"
                     /locus_tag="ACL8C7_000319"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HGS1394586.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            38083..38442
                     /locus_tag="ACL8C7_000320"
     CDS             38083..38442
                     /locus_tag="ACL8C7_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HGS1394587.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            38535..39167
                     /locus_tag="ACL8C7_000321"
     CDS             38535..39167
                     /locus_tag="ACL8C7_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HGS1394588.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDICLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLDNRQTFIDQVGVTQLHGTKVVF"
     gene            39211..39867
                     /locus_tag="ACL8C7_000322"
     CDS             39211..39867
                     /locus_tag="ACL8C7_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HGS1394589.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            39937..40980
                     /locus_tag="ACL8C7_000323"
                     /pseudo
     CDS             39937..40980
                     /locus_tag="ACL8C7_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261078.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-isopropylmalate synthase regulatory
                     domain-containing protein"
     gene            40992..42029
                     /gene="leuB"
                     /locus_tag="ACL8C7_000324"
     CDS             40992..42029
                     /gene="leuB"
                     /locus_tag="ACL8C7_000324"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HGS1394590.1"
                     /translation="MAKKIVALVGDGIGPEIMEAGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAGPPLPDETLKASREADAILLAAIGSPQYDGAAVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKYLSPLKPERISGVDFVVVRELTGEIYFGDHILEERKARDINDYSYEE
                     VEWIIRKAFEIARNRRKILTSIDKQNVLATSKLWRKVAEEVAQDFSDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLGVMPSASHSENGPSLYEPIYGSA
                     PDIAGQGIANPISMILSVAMMLRDSFGRYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            42026..42295
                     /locus_tag="ACL8C7_000325"
     CDS             42026..42295
                     /locus_tag="ACL8C7_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HGS1394591.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIQEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            42299..42658
                     /locus_tag="ACL8C7_000326"
     CDS             42299..42658
                     /locus_tag="ACL8C7_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HGS1394592.1"
                     /translation="MAGSSREYAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKFLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            42820..43443
                     /locus_tag="ACL8C7_000327"
                     /pseudo
     CDS             42820..43443
                     /locus_tag="ACL8C7_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004899133.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Sua5/YciO/YrdC/YwlC family protein"
     gene            43609..45522
                     /locus_tag="ACL8C7_000328"
     CDS             43609..45522
                     /locus_tag="ACL8C7_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HGS1394593.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENSIFDMKRSTNEFIGRSAMVTK
                     LLCIYSEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNDQ
                     TGQQDTGDNDADY"
     gene            45509..46825
                     /locus_tag="ACL8C7_000329"
     CDS             45509..46825
                     /locus_tag="ACL8C7_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HGS1394594.1"
                     /translation="MRITDNQYKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKILHINLTSLDVALSREERLYQLLVYLFPKYLQAAIRKGLYKEYHRFSHNDSNVKGV
                     IDVRSHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            47000..47986
                     /locus_tag="ACL8C7_000330"
     CDS             47000..47986
                     /locus_tag="ACL8C7_000330"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HGS1394595.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVRQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            48050..48121
                     /locus_tag="ACL8C7_000331"
     tRNA            48050..48121
                     /locus_tag="ACL8C7_000331"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:48083..48085,aa:Arg,seq:ccg)
     gene            48304..49002
                     /gene="rnc"
                     /locus_tag="ACL8C7_000332"
     CDS             48304..49002
                     /gene="rnc"
                     /locus_tag="ACL8C7_000332"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HGS1394596.1"
                     /translation="MKELQTVLKNHFAIEFADKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFNQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVIIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            48993..52532
                     /gene="smc"
                     /locus_tag="ACL8C7_000333"
     CDS             48993..52532
                     /gene="smc"
                     /locus_tag="ACL8C7_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HGS1394597.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAVLEDKRNS
                     LSQEKSDKESSLVLLEENLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLATAKEKASQQKDELETAKVQVQK
                     LLTDYQAIAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVHYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDVIAASAGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARKVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLRSDEVSLKNLQDELARLTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEELNRLSEGEWQADKEKCQERLTTITSEKNNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVTDIERLGKELDNLDIEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELDNLNLAEQEVQDLEK
                     AIRSLGPVNLDAIDQYEEVHSRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            52529..53323
                     /locus_tag="ACL8C7_000334"
     CDS             52529..53323
                     /locus_tag="ACL8C7_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGS1394598.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMERLKSLLTSYKEKGIYFAVAS
                     GRGFLSLEKLFADVRNDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLQTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNEHVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARSEILELAETVIGHHKDQSVIAYMEGL"
     gene            53323..54141
                     /locus_tag="ACL8C7_000335"
     CDS             53323..54141
                     /locus_tag="ACL8C7_000335"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGS1394599.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKATLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGHEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            54145..55434
                     /gene="ftsY"
                     /locus_tag="ACL8C7_000336"
     CDS             54145..55434
                     /gene="ftsY"
                     /locus_tag="ACL8C7_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HGS1394600.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVP
                     QEEAEVEIVEQAVFQEEEIQDTVEESQDSEPAVGVSQEEIEELPNSEELPEEEKLEHE
                     GTIEENNSEVLEPERPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKRTGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVIFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(55480..56967)
                     /gene="zwf"
                     /locus_tag="ACL8C7_000337"
     CDS             complement(55480..56967)
                     /gene="zwf"
                     /locus_tag="ACL8C7_000337"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HGS1394601.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRLE"
     gene            complement(57116..57856)
                     /locus_tag="ACL8C7_000338"
     CDS             complement(57116..57856)
                     /locus_tag="ACL8C7_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS1394602.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(57856..60021)
                     /locus_tag="ACL8C7_000339"
     CDS             complement(57856..60021)
                     /locus_tag="ACL8C7_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HGS1394603.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            60190..61143
                     /locus_tag="ACL8C7_000340"
     CDS             60190..61143
                     /locus_tag="ACL8C7_000340"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HGS1394604.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLVFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEELVTRAWLIPQLAKRTNLKVAIIISSSLFTLLHLGNPGITFLS
                     AIDLFLFGVAMSLYLLKTDTIWGIGGIHGAWNFAQGNLFGVLVSGQSSGTSIMRFTPQ
                     GNQDWLSGGSFGIEGSIVSSIILFLLILYLAHQLKKENERM"
     gene            61220..63208
                     /gene="uvrB"
                     /locus_tag="ACL8C7_000341"
     CDS             61220..63208
                     /gene="uvrB"
                     /locus_tag="ACL8C7_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HGS1394605.1"
                     /translation="MINRITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQTELEEQL
                     AVFENEGKLLESQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYEGEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKTVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            63218..63781
                     /locus_tag="ACL8C7_000342"
     CDS             63218..63781
                     /locus_tag="ACL8C7_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGS1394606.1"
                     /translation="MIYLRKLKKEDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKIAMLQWIDRTFQDYLELEHLGLTTWSGNIGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDDYYQINENS"
     gene            63747..64235
                     /locus_tag="ACL8C7_000343"
     CDS             63747..64235
                     /locus_tag="ACL8C7_000343"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1394607.1"
                     /translation="MTIIIKLMKTPEEIEGKSLVHWQTWREAYDDLLPAEFQETMTLE
                     RCRFFSKKYPENTWIAMDGVKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LVKVALTALDHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            64307..64774
                     /locus_tag="ACL8C7_000344"
     CDS             64307..64774
                     /locus_tag="ACL8C7_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HGS1394608.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRSPETNRWSGYAFPGGH
                     VENGESFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLRS
                     SDEGEVSWVQKDQIPNLDLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(64771..65286)
                     /locus_tag="ACL8C7_000345"
     CDS             complement(64771..65286)
                     /locus_tag="ACL8C7_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HGS1394609.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGVHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(65298..65825)
                     /locus_tag="ACL8C7_000346"
     CDS             complement(65298..65825)
                     /locus_tag="ACL8C7_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGS1394610.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWIFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(66107..66670)
                     /locus_tag="ACL8C7_000347"
     CDS             complement(66107..66670)
                     /locus_tag="ACL8C7_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGS1394611.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(66654..67205)
                     /gene="coaC"
                     /locus_tag="ACL8C7_000348"
     CDS             complement(66654..67205)
                     /gene="coaC"
                     /locus_tag="ACL8C7_000348"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HGS1394612.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLITPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(67217..67906)
                     /gene="coaB"
                     /locus_tag="ACL8C7_000349"
     CDS             complement(67217..67906)
                     /gene="coaB"
                     /locus_tag="ACL8C7_000349"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004632 - phosphopantothenate--cysteine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HGS1394613.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGYEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISTDQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            68136..69806
                     /locus_tag="ACL8C7_000350"
     CDS             68136..69806
                     /locus_tag="ACL8C7_000350"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HGS1394614.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNLVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELEIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAAL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            70134..71309
                     /gene="mutY"
                     /locus_tag="ACL8C7_000351"
     CDS             70134..71309
                     /gene="mutY"
                     /locus_tag="ACL8C7_000351"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HGS1394615.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNSGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            71364..72068
                     /gene="yycF"
                     /locus_tag="ACL8C7_000352"
     CDS             71364..72068
                     /gene="yycF"
                     /locus_tag="ACL8C7_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HGS1394616.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            72061..73410
                     /gene="vicK"
                     /locus_tag="ACL8C7_000353"
     CDS             72061..73410
                     /gene="vicK"
                     /locus_tag="ACL8C7_000353"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HGS1394617.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            73412..74221
                     /locus_tag="ACL8C7_000354"
     CDS             73412..74221
                     /locus_tag="ACL8C7_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGS1394618.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            74312..74554
                     /gene="relB"
                     /locus_tag="ACL8C7_000355"
     CDS             74312..74554
                     /gene="relB"
                     /locus_tag="ACL8C7_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HGS1394619.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            74556..74810
                     /locus_tag="ACL8C7_000356"
     CDS             74556..74810
                     /locus_tag="ACL8C7_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HGS1394620.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEGPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            74857..75630
                     /locus_tag="ACL8C7_000357"
     CDS             74857..75630
                     /locus_tag="ACL8C7_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion channel"
                     /protein_id="HGS1394621.1"
                     /translation="MKKKCFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLAKLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPASIFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLQDELSSQRILLEKQSKKIEELHKMIQDLIEKT"
     gene            complement(75893..76879)
                     /locus_tag="ACL8C7_000358"
     CDS             complement(75893..76879)
                     /locus_tag="ACL8C7_000358"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HGS1394622.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            77073..79541
                     /gene="gyrA"
                     /locus_tag="ACL8C7_000359"
     CDS             77073..79541
                     /gene="gyrA"
                     /locus_tag="ACL8C7_000359"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HGS1394623.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMIGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            79541..80284
                     /gene="srtA"
                     /locus_tag="ACL8C7_000360"
     CDS             79541..80284
                     /gene="srtA"
                     /locus_tag="ACL8C7_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HGS1394624.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
     gene            80528..81325
                     /locus_tag="ACL8C7_000361"
     CDS             80528..81325
                     /locus_tag="ACL8C7_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HGS1394625.1"
                     /translation="MISSEFISKIEFACNKKEGLYSQSKFKYAIRSIFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLIHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            81473..82732
                     /locus_tag="ACL8C7_000362"
                     /pseudo
     CDS             81473..82732
                     /locus_tag="ACL8C7_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365067.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase family
                     protein"
     gene            82828..84102
                     /locus_tag="ACL8C7_000363"
     CDS             82828..84102
                     /locus_tag="ACL8C7_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HGS1394626.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            84112..84990
                     /gene="truB"
                     /locus_tag="ACL8C7_000364"
     CDS             84112..84990
                     /gene="truB"
                     /locus_tag="ACL8C7_000364"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HGS1394627.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVVAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALTLEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            85231..85533
                     /locus_tag="ACL8C7_000365"
     CDS             85231..85533
                     /locus_tag="ACL8C7_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGS1394628.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKHQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFSLWIAKAPSQERGRLAFLQMLAQILQGFR"
     gene            85641..86279
                     /gene="udk"
                     /locus_tag="ACL8C7_000366"
     CDS             85641..86279
                     /gene="udk"
                     /locus_tag="ACL8C7_000366"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HGS1394629.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            86407..87747
                     /gene="xseA"
                     /locus_tag="ACL8C7_000367"
     CDS             86407..87747
                     /gene="xseA"
                     /locus_tag="ACL8C7_000367"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HGS1394630.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQSRTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            87725..87937
                     /locus_tag="ACL8C7_000368"
     CDS             87725..87937
                     /locus_tag="ACL8C7_000368"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HGS1394631.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            87934..88809
                     /locus_tag="ACL8C7_000369"
     CDS             87934..88809
                     /locus_tag="ACL8C7_000369"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HGS1394632.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDSYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            88802..89617
                     /locus_tag="ACL8C7_000370"
     CDS             88802..89617
                     /locus_tag="ACL8C7_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HGS1394633.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            89610..90041
                     /locus_tag="ACL8C7_000371"
     CDS             89610..90041
                     /locus_tag="ACL8C7_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGS1394634.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            90048..91715
                     /gene="recN"
                     /locus_tag="ACL8C7_000372"
     CDS             90048..91715
                     /gene="recN"
                     /locus_tag="ACL8C7_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HGS1394635.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRTIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLDLNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            91717..92445
                     /locus_tag="ACL8C7_000373"
     CDS             91717..92445
                     /locus_tag="ACL8C7_000373"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGS1394636.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            92524..94347
                     /gene="lepA"
                     /locus_tag="ACL8C7_000374"
     CDS             92524..94347
                     /gene="lepA"
                     /locus_tag="ACL8C7_000374"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HGS1394637.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            94760..95235
                     /locus_tag="ACL8C7_000375"
                     /pseudo
     CDS             94760..95235
                     /locus_tag="ACL8C7_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            95273..95575
                     /locus_tag="ACL8C7_000376"
     CDS             95273..95575
                     /locus_tag="ACL8C7_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS1394638.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSVPVFDNIRLPAKQNMV"
BASE COUNT        29052 a        17051 c        21201 g        28279 t
ORIGIN      
        1 gccacgtcca gaacatccta agaaagcaga cgctcaaacc attgtcgcgt ctaaaaataa
       61 aatctcaatt caagaagaca agaaagcggt ttaaatatag tagacgtttt cgtaaggttc
      121 gcttgatgta ccaaatagta cgcccatgca aaagaatatc tattttgttg tcttggacct
      181 gcatacgacg gatagagata aaattatcca gctattcaag gattggacgg attatagtgc
      241 caagttggtc gagggggaat tggttaaaaa agatggacag aatgctctct ttcctccgag
      301 cgatactggt gagacagttg ggctcaatcc tcatcgtttg acgctgactt ttggtgtatc
      361 tgcaagtttc ttgaaaaaga tgaacttgga aaacaagcgc cctcgactgt tcagggattt
      421 acctctattt cctaaggagc aattacgtga aaaatatact ggtggagata ttgtgattca
      481 tgcttgtgca gatgatgagc aaattgcctt tcacgttatt cgcaatctca tacgtaaggg
      541 gagaaatgcg gtgccccttc gttggagtca gtctggattt gcagctatcg gggacgaatg
      601 gagactccgt ggaacctctt tggttttaag gatggaacag caaattcaac caaggagcaa
      661 gactttgacc gcgttatctg ggctgatagt aaggactgga tggaaaatgg ttcttatatg
      721 gcagttcgtc ggattcagat gtttttagag acctgggacc gcactggtct cgaagaacaa
      781 gaaaatacct ttggtcgtta caaggaaagt agtgcccctt tcggtaaaaa aatgagtttg
      841 atgaagtgaa tttgagtttt ttgctagatg attcgcatgt tcgtttggct aagtaagtgg
      901 acaagccact tttgcgttgt tcttactctt actcagatgg cattgatgaa aagactggtc
      961 agtttgatac gggattgctc ttcatttctt tccagaagga tcctgataac tttgttaagg
     1021 ttcaaactaa cctaggtgct actgataaga tgaatgaata catcactcac ataggtagtg
     1081 gactttttac ttgctttggt ggtgtggaga aaggaggcta cattggtcag aaattattgg
     1141 aaggctaaaa gctggttact agttttagct ttgtcatttt taattctttc cccagcaggt
     1201 gcccaagaaa gcttgagttt tttctttgtg aaaatcacag atgcatccaa agcggttaaa
     1261 aatggtggtc agactgagac ccagaaactc gttacgaaga tggcatcaga cttcgaaaga
     1321 gtagaaaata aggattctga ggttggtaag attgttaagg aaaagttagc tctatctgga
     1381 gatattactg aagccaaact caccgaaatt tcctcagctc tattagcttt tgaaaaagaa
     1441 caaaatcctg ttgacctaga tgcggaaaag gaaaaattgg taaaccgtct aagtcctcgt
     1501 tttgaaacct tggaacaggc tattgccttc aaagatttgg aaaaagtccg agaagctttt
     1561 aagaaaatga attccacttg gaccatcaat gaaagtgtgg ttcgttacaa tagtatagct
     1621 cattatggac gtgttgaaac agctatttcc ttcctgccta gtagcatgga aaccgaacct
     1681 acagatgagt ctggaacatg aaaacagcag ttgatttcaa gaaacaaaaa agaacagccg
     1741 aaactgttct cttatcatta tttgagaccg tattttttgt tgaaacgatc cacgcgtcca
     1801 tctgcttgag tgaacttttg acgtccagtg tagaatgggt gtgagtctga tgaaatttcc
     1861 acacggatca atgggtaagt ttcgccttcg aactcaactg tttcgttaga gcgttttgtt
     1921 gaaccgctaa ggaattggta accagtagtt gtgtccatga agacaactga gcgatattct
     1981 ggatggatat cttttttcat tttgcaatat ttcctttctg ccatggtctc tttgcgagcc
     2041 atagattgtt accatactag tctatcagat tctgaaaagt ttggcaagta ttttatcagt
     2101 ttttaagcaa gttttttaac ttttggtaga tgatttcgtt ttcttctagg ctataggaat
     2161 tagcaccact tgctagaggg tggcctccac catcatgctc cttggcgatt tcattgatag
     2221 gatggatttt actgcgtaag cgaacgcggt agtggccatc agcctgttcg acaaaaattc
     2281 cccagagact cactctgtca atgcgtccag gtgcaccgac aatggctgca gtttcagcat
     2341 cggttacatt gtattgtttc aagacttctt gactcaggat aacgcgagca gcaccatttt
     2401 catccacttc cagatggtcg tagatgtagc cttgcagttt agcaattttg tagctcatag
     2461 tgtccatttt gcgagtgaga gccgcaaagt caaagttatg ttctctcaaa taagcagcca
     2521 ggcgaagagt ccgtgcagtg gtagaagggt agaggaagcg acctgtatca ccgacaattc
     2581 ctgcaaagag caactcagca tcgcgatctg ccaaggctag ttgggttgtt tgggcaaata
     2641 gggtgatcat ctcgctagcg ctacttgaac tagtatcgac ccaagacagg tcaccgtata
     2701 catcatcatt tggatggtgg tcaatcttaa tgagaaaatc accttgacta tagcgcttat
     2761 catcgatacg agcagtatta gctgtatcac agacgatgac aagtgcgcct tggtaggctc
     2821 tatcttcaac aagatccatc tcagccatcc aagtaagagt tggttcatca aaaccgacgg
     2881 ctttgatggt tttttctggg aaatgatgtt ccagcaaggc tttcaatccc acctgacttc
     2941 ctaaggcatc agggtctggt ttcatatgac gatgaatgat aatggtgtcg tattctttaa
     3001 ttttttctaa aatttgttgg caaatctcca taaataacct caattctttc tcatttcatt
     3061 gtagcacaag aatttttatt tttaaaatga aaaagatgtg atataatgga gaaagataaa
     3121 ttgaggagga cgatatggca ttagcaaaaa ttgtatttgc cagtatgacc ggtaataccg
     3181 aagaaattgc agatattgta gcagacaaat tacgtgactt gggcttggat gttgatgttg
     3241 atgaatgtac aactgttgac gcttcagact tcttggaagc agacatcgct atcgttgcga
     3301 cctatactta tggtgatggt gaattgccag atgagatgat ggacttctac gaagacctag
     3361 cagatctcaa cttgaatggc aaaatctacg gagtggtcgg ctcaggagat accttctacg
     3421 atgaattctg taaggctgtt gatgactttg accgtgtctt tgtgtcaaca ggagcagaaa
     3481 aaggttcaga gtgtgttaaa gttgatcttt ctgccgagga agaagatatt gaacgcttgg
     3541 aacaattcgc agaagaattg gttgctaaag taggataagc ataaaagtgc gctgatgtaa
     3601 tcaatcagtg catttttctt atcgagagtt gggattttac tagcctaatt gatggctttt
     3661 tgatacaata attcaaataa aggaggagac tgtatggatt tagatattat tcgtcaagaa
     3721 atcgatcaaa tcgacgacca aattgtcaaa ctgttagaag aacgaatgca cttagttgaa
     3781 ggagttgtcg cttataagaa ggcttcaggg aaaccgattt tagatactaa gagagaagca
     3841 gttatttttg aaaaggttag aagtcgtgta gaggacaagc gctatcagga gactattgtc
     3901 gcgacttttt cggacatact caaacgttcg cgtgattatc aggatcaaaa tatcaaatga
     3961 aaaaagaaca attttatccg ctagggattt ttctagctgc tatgttgggc ggacttgtcc
     4021 gctacctagt ttccactttg ttaccagcca gtccagattt cccttggggc actctctttg
     4081 tcaactatct gggaattttc tgcttgattt atcttgtcaa gggctatctg gtctataagg
     4141 ggactagtaa gggcttgatt ttagcactgg ggacgggttt ttgcggaggt ttaacaactt
     4201 tttccagcct aatgcttgat actgtgaagc tgcttgatac agggcgttat cttagtttga
     4261 tactgtattt gcttttgagt atcggtggag gcctgctttt agcttactat ttggggagga
     4321 agaaatggta atcgtctatc ttgcaatcgc ctgtggcttg ggagcactcg tacggtattt
     4381 cttttctcgc tataatcaag cttctaaatt gccactcgga acgctcatag ctaatctttt
     4441 aggttgtttt ttaattggag tattctacaa tcatgtagag tctaaggaag tatatgctat
     4501 tctagcaaca ggattttgtg gcggtttaac aactttttcg accttgaatg acgaacttca
     4561 aagactgcta agtgataaga aggtctttta ttcttacctg actttgactt acataggtgg
     4621 tttggttgcg atttttttag gaattttgct ataaatttct ttactttttt ttagaaattt
     4681 ggtaaactat atcttgtgtg taatggacgc acaaaaatac agtttatccg ctgaggaaga
     4741 ttcctcaaga ttgacaaaga taggagaata aaatgaatcc attaatccaa agcttgactg
     4801 aaggtcaact tcgtacagat atcccatcat tccgtcctgg tgacactgtt cgtgtacatg
     4861 cgaaagttgt cgaaggtaac cgtgaacgta tccagatttt tgaaggtgtt gttatcgcac
     4921 gtaaaggtgc tggaatctca gaaaactaca cagttcgtaa aatctctaac ggtgtaggtg
     4981 ttgagcgtat cttcccaatc cacactccac gtgttgaaaa aatcgaagtt gttcgttacg
     5041 gtaaagtacg tcgtgcgaaa ttgtactact tgcgtgctct tcaaggtaaa gcagctcgta
     5101 tcaaagaaat ccgtcgttaa ttcgactaaa aaactctgct catttagcag agtttttatc
     5161 tagctccctt agttcaatgg atataacaac tccctcctaa ggagtagttg caggttcgat
     5221 tcctgcaggg ggcagtaatt agacatcaaa gaagtttgtc aaaaagtctt tgatattaaa
     5281 agaacgcata atataggtga ttttgtgtgt ctccataata ttatgcgttt tattattgaa
     5341 aaatttgggc aatcatcaga taaaattgag actatatcga gtatataaat gtttgtataa
     5401 ttaatttatt caacatcgtc aagttctaaa ttatttaaag gactataaca ttcatatttc
     5461 tttaagtaat tgtttatttc ttcagcagta gaacaaggta aattaactct taaatagtca
     5521 atatcttctt tagataaaaa atgatttgca ttcaaaattg agaagcgaaa taatgcttca
     5581 tcaaaagcaa aatcataatc gtcatcagat aatgattcca ttaatgtttg aatatgtttt
     5641 agtgagtagt caggtatcga atcgggataa tatactggat aatcagtggc tgaaaaattg
     5701 ttttctaatc ctgaactagt aattatcaaa gattctatgt aatatattaa agaatgttta
     5761 atattacctt cttgttccaa atgtcttcct tgagcctttc gtgtgttaga taaacatcca
     5821 aaatctcctg atacagtatt cctatgagct tgtttattta aaatactcca ttttatatca
     5881 ccaaaagttg ctttaaaaga gatattattt ttttctttac aataatcttc catagttatg
     5941 tctttatcat agtatgcttt gatatagtca ctatgttcga taataagatt ttgtgcttct
     6001 tttgttagtt taaattcgaa cggaatatct aatttgtcaa cgttgatatt attaattatt
     6061 cttgtaatta attctgcttt ttttccagaa gtaggtaaat tatgtttaga taatatagtt
     6121 tttaattcta ctactttaag atatgataaa gtcttatttt tagtgaagta tcctaatttg
     6181 tataattgat tgtgtgtaga ttcagggtca atttgaagag agtatttaaa atatcttggg
     6241 aaattataat ttctccctgt tttttgagtc caatctatga gtatgagttg cccaggagta
     6301 aggccgcact ctaatttgtt taggtaaaaa ttgttacaat cagaatttgt gtctctatta
     6361 tgattatttt gttttaaatt aaatagtttg ctaaaaaaat tcattggatt ttattgctaa
     6421 tcaattctta ttgaaaaatg atacttttac agtacccatg tacggatggc atgggcaacg
     6481 ccagattcat cattagattt agtgatgtat ttggcgattt ttttgatttc tggatttcca
     6541 ttttccatga caacagggtt gccaacgact tccagcatgg cacggtcatt ttcttcgtct
     6601 ccgatagcca tggtttcatc tttggttaat cctagttttt cagctaagtg agtaatagct
     6661 gaacccttgt ctacattctt tttaaggagt tcgaggtaga aaggagcaga tttgttgata
     6721 gagtagtgct cgtaaaattc ggctggtatt ttttcaatcg cagcatcgag aatttctggt
     6781 tcatcgataa acatacattt aacaatttct ttgccagcca tttcttcagg ggtacggtag
     6841 aagataggca tgctgacgag ggttgattcg tgtacagtgt atgttccgat attgcgattt
     6901 gcagtataga taccgtcctt ggtaatggca tgcatgtgga caccgagctt gcgactgagg
     6961 aattccatat ccagataatc ctcataggtc aaggattcgc tgataatctc atggccagta
     7021 gcagtttctt ggacaagggc accattgaag gtcaccacat agtcaccttg gtctctcaac
     7081 tgcaagtcgt ctagaagttt ggcaacacct gcgatggggc ggccagttgc aatcacgact
     7141 ttgacaccag cttctttggc atcttggatg gcagaaaaga cttcaggagt gatttccttt
     7201 tggctgttga caagggttcc gtcgatatca acggcaatta gtttaatact cataaatttc
     7261 ctcttctagt ttttatttgg ggtaaaatga tcgttctcaa tcaagtataa aaattgctgg
     7321 gtaatgctag caaagatact gttttgatct aacatttctt tcggaaaata gaaacgatta
     7381 tctccgtgac gactaccagc aagggattgg acgataggag acaggctaga gagttcggcc
     7441 agttctccat tcttttgtaa aatctcaatc tgtgtccgtg gattttcaga ttcgggacga
     7501 tagatatcat aagggaggtc aaagttctta tgaatggcag tatagtagtc gggatcaaag
     7561 ccaatgtcct caaccaattt tctcatgcta gcgagttggt cttgatcttc ttgtgaaaag
     7621 gtaatggatt taaagacctt gcggttgaca aagcgttgcg ataaatctgc gagaattttg
     7681 tcaggactgg tcatccagag ctggaagtag gtattcatca caccatcatc tagagccaga
     7741 tagtcagaca aggtcacatt tttttcaaag aaaggcagga ggtgtgggga agttcgtgca
     7801 aagaagtctt tgtccttagg gtagagttcc ttagcgcgct tgagaagatt ctgtaggaga
     7861 acttccatag cgcgtgttgc tgggtggaaa tagacctgca tatacatctg gtagcgactg
     7921 aggacatagt cttcgatggc gtgcatgcca ttgcgctgaa aggcgatacc attttcgata
     7981 ggacgaatga ctcggaggat tcgagtcagg tcaaattccc cataggatgc tcctgtaaaa
     8041 taggagtcac gcaagagata gtccatgcga tctgcgtcaa tctgactaga aatgagttgt
     8101 acgacctgct tgttaggata ggtatggtct atgacactgg caactttctc tggaaaatcg
     8161 ggcgctactt gtagcaatac ttggtgaatc tctgtctcag gactttgaat aatctcctga
     8221 gtaatagctt catggtctgt atcaaagaga tgttcaaaag tatgggagta ggcgccatgc
     8281 ccaaggtcat gtaggagagc agcgatcatg gtcaagagag actcggcagg attccattcc
     8341 tcaggatatt tttcttcgaa aatctctgtg atgcgtcgtg caatttcata gactcctaga
     8401 cagtgagaga agcgactgtg ttctccaccg tggaaggtat aactggaagt tcccagttgt
     8461 ttgatccggc gcaaacgctg aaattctttt gtattaatca agtcatagat gatttgatta
     8521 ttgacatgga tgtagttgtg aactgggtca cggaatactt tttcgttcat atgaccatta
     8581 tagcaaaatc ctgctctttt tggtaaaata gtaggacaag agacaagaaa gagggcctga
     8641 tgtgaagatt cggatgcgaa atacaattca gtttgatgag cagttggaag tgattgacca
     8701 gctttatgat gtggaagtgc atgaaaaagg agattatagc tacctgcttt tctataatga
     8761 ggaaaaggaa aaagtagtga ttaaatttca tggtcaagaa cttgtgatga gccgattttc
     8821 taatcccaag accattatgc gctttctaaa gaatagcgat agtttagcct atattcctac
     8881 acctatgggc atgcaggagt ttatcatcca aacgagccat tatcaagttg ataggcaaaa
     8941 gattgaacta gattatcaac tacaaaatca agagggacat ccttttgcca gctatcaatt
     9001 ggaaattact tggggctagg ctcatgtctt tttcaaattt agctatctat cttcttggat
     9061 cggcttccta gtgtggtaga ttaggctaat ttttggtata ataaaagtta tggaaatcga
     9121 aaaaaccaat cgtatgaatg cgctctttga attttatgcg gcgcttttga cagataagca
     9181 aatgaattat atcgagctct actacgctga tgattacagc cttgctgaaa ttgccgagga
     9241 gtttggtgtc agtcgtcagg ctgtctatga caatatcaag cgaacagaaa agattctgga
     9301 agattatgag atgaaattgc acatgtactc ggactatatt gtccgcagtc agatttttga
     9361 tcagattttg gagcgctatc ccaaggataa ctttctgcag gagcagatag aaattttaac
     9421 aagcattgat aatagagaat aagaggaaga aaaatggcat ttgaaagttt aacagaacgt
     9481 ttgcagaacg tctttaaaaa tctacgtaaa aaaggaaaaa tctctgaatc tgatgtccaa
     9541 gaggcaacca aagaaattcg cttggccttg ctcgaggccg acgttgcctt gcctgttgta
     9601 aaggacttta tcaagaaagt tcgtgagcgt gcagtcgggc atgaggtcat tgatacactt
     9661 aatcctgcgc aacagattat taaaatcgtt gatgaggaac tgacagccgt tttaggttct
     9721 gatacggcag aaattatcaa gtcacctaag attccaacca tcatcatgat ggttggttta
     9781 caaggggctg gtaaaacaac ctttgctggt aaattggcca acaaactcaa gaaagaagaa
     9841 aatgctcgtc ctttgatgat tgcggcggat atttatcgtc cagctgccat tgaccagctt
     9901 aagaccttgg gacaacagat tgatgtgcct gtctttgcac ttggaacaga agtaccagct
     9961 gttgagattg tacgtcaagg tttggagcaa gcccaaacta atcataacga ctatgtcttg
    10021 attgatactg cgggtcgttt gcagattgat gagctcctca tgaatgagct tcgtgatgtg
    10081 aaagcattgg ctcaaccaaa tgaaatcttg cttgtcgttg atgctatgat tggtcaggaa
    10141 gcagccaatg ttgcgcgtga gtttaatgct cagttggaag tgactggggt catccttacc
    10201 aagattgatg gcgatactcg tggtggtgct gctctgtctg ttcgtcacat tactggaaaa
    10261 ccaatcaagt tcactggtac aggtgaaaag attacggaca ttgaaacctt ccacccagac
    10321 cgcatgtcta gccgtatcct tggtatgggg gatatgctca ctttgattga gaaagcttct
    10381 caggaatacg atgaacaaaa agcccttgaa atggctgaga agatgcgcga aaacaccttt
    10441 gattttaatg atttcatcga tcaattagat caggtgcaaa atatggggcc gatggaagac
    10501 ttgctcaaga tgattccagg tatggccaac aatccagcac ttcaaaacat gaaggtggat
    10561 gaacgccaga ttgctcgtaa acgtgccatt gtgtcttcga tgacacctga agaacgtgaa
    10621 aacccagatt tgttaaatcc aagccgtcgc cgtcgtattg ctgctggttc tggaaataca
    10681 ttcgtcgaag tcaataaatt catcaaggac tttaaccagg ctaaacagct catgcagggt
    10741 gttatgtctg gggatatgaa taaaatgatg aagcaaatgg ggattaatcc aaataacctt
    10801 cctaaaaata tgccaaatat gggaggaatg gatatgtctg cccttgaagg aatgatggga
    10861 caaggcggta tgcctgactt atcagctctc ggaggagcag gaatgccaga tatgagccag
    10921 atgtttggtg gcggtttgaa aggtaaaatt ggtgaatttg ccatgaaaca gtccatgaaa
    10981 cgtatggcta acaaaatgaa gaaagcgaag aagaaacgca agtaagacaa gagattgatg
    11041 caaatctcat ttgatgagaa aataaagtaa aaatttctat gataaaacgt acagtatcaa
    11101 ggttttagaa tatctgatat tatacgtttt ttgattttaa taattttgtt aagacacttt
    11161 tattatggta tgcgaaaaat ccactcagct gtctgagtgg attaggtgta tttagactct
    11221 tagtctttat tttcgtatgg caagatcaag ttcaagatga ttcctgtcat ggctgaaagg
    11281 gcagtacctg aaagtgtaac tggaccaagt ttaaggatag ctcctccaag tccaagaacc
    11341 aacatagcac ttgcgatgat gaggtttcgc atttgagcga aatcaacacg ttctttaatc
    11401 aagactttca aaccattgct ggcgataacc ccatagagaa ggattgacat accaccaagt
    11461 acagcgtttg gaatagttga aatcaaggca gtgaatttac caaggaagct gagggcaatc
    11521 gcgatgaagg cagcgttacg gataactgag acagaagcga tacgagtcat accgataacc
    11581 cctgtatttt ctccgtaagt tgtattggct ggtccaccaa ggaaggcaga aacagaagtt
    11641 gcgataccgt caccaagaag agtacgatga agacctggtt cttttaagaa ttgacggcca
    11701 cagatttgac ccaaaacagt atggtctccg atatgttcag aaattgttac gatagcgatt
    11761 ggcaagatag cgatggcttc tggaccaaag taaagattgt actctttaaa ggcaccacct
    11821 gtgctaaatg gcaagtagaa accaggaatt tcgaaccagt tggctttaag aactggtgta
    11881 aagtcaacca agccaagagt tagtgcgaaa aggtaaccac cgataatggc aaagaggaat
    11941 ggaatgattc gtaggaagcc ttttcctttt gtattgataa aggcagcaat taggaaagta
    12001 acaacggcta ccagagcatt tttccaattt ccgtctgcta caagacctgc attggtaaca
    12061 gctgaacctg caagtccaag accgataacg atgatcatag gaccgataat gattggtggc
    12121 aagagtttat caatccattt tgttcctaca aatcggatgc tggtagcaac aaggacatag
    12181 accaaaccag tcaagataac ccctgtttgg gcagcagata catccccccc catttctttc
    12241 atagccagtg acatagctgt gataaaggca aatgaagaac ctagataaac tggaacttta
    12301 aaaccagtag caatcatgta gatgagtgtt ccaacacctg aagcaaaaag ggcaacagat
    12361 acaggcattc ccaaaatcaa tggtaccaag atggtcgcac caaacatggc gaaaacgtgt
    12421 tggaagctaa ggagaattcc ttttccatcc gaaggacgtt ggtcaacgtc tagtaacaaa
    12481 tcaacagttg attcttgttt catataaacc tcacttttgg gcatcagaaa agagcccatt
    12541 attttacagc aataggccct cagagtaaga cttctctaaa atctagactt taaagagttt
    12601 taaatatttt tgcgtcttcg tcacctcacg ggatgacatt aaaaaccttt gcttaggata
    12661 gtatagcaga aaaaaatgat tttgtaaatc attttttccc gagcctagaa ataaaagagc
    12721 gaggctgatt ttgtaaacat ttgtttacta aaaaatttaa agtgggcgtt tatttggcat
    12781 accagcctta cgtggatatt tatttggtgt ttcttttttc ttttctacca ctgtgatata
    12841 gcgcggatct ctattcggta gggcgtagct gagattgtct tcgaccttac taaaaaggag
    12901 attgagggca ttcttagctt ctaataattc ctcaggcgca ttgctggcct tgagtgccaa
    12961 tagttttcca ccaaccttaa ggtagggaat ggtcaattca gataggacct gcatacgggc
    13021 aaccgcacga gctgttacaa aatcatattg agcacggaag ttcttgtctt gggcaaaatc
    13081 ttcggcacgt ccgtggtaga aatgaactcc gttcaaatcc agttcttgag ccaagagttg
    13141 taggaagttg atgcgcttat tgagtgaatc aataatggtc acatctaact ccggatagag
    13201 aattttcatt ggtagactag gaaatcctgc cccagccccg atatcaagaa gtttgatagt
    13261 ttcattggga atcaaacctt gaagaatggg tgcaatcgaa tcgtaaaaat gtttgagata
    13321 aacttcttcc ttgtccgtaa tcgccgtcaa attaatcttc tcattccact cgaccaagag
    13381 ctcaaaataa cgttcaaatt gttctttttg ctggtccgaa agtggaagat tctgctcggc
    13441 aagcaagttg taaaatgttt ttggtttcat agttatttcc ttctttagta tcatcttatt
    13501 ttaccacaat catagaaaat ttgatatact ggtactaatc taaaagcaga aaggacttat
    13561 attatgactt ggattattct tggagttatc gctcttattg ttatttttgt gattgttagc
    13621 tataacggtt tggttaaaaa tcgtatgcaa accaaggagg cttggagtca gattgatgtt
    13681 cagttgaaac gtcgaaatga cctcttgccg aacttgattg agactgtaaa aggttatgcc
    13741 aaatatgaag gttctaccct tgaaaaggtg gcagaactac gtaaccaagt ggcggcagcg
    13801 acttcaccag cagaagctat gaaagccagt gatgccctca ctcgtcaggt ttcaggtatt
    13861 tttgcagttg cagaaagcta tccagatttg aaagctagtg ctaactttgt taaattgcaa
    13921 gaggagttga caaacacaga aaataaaatt tcttactctc gtcaactcta taacagtgtt
    13981 gtcagcaact acaatgtaaa attagaaact ttcccgagca atattatcgc tggaatgttt
    14041 ggatttaaag cggcagattt ccttcaaaca cctgaagagg aaaagtcggt tcctaaagtt
    14101 gattttagcg gtttaggtga ctaagatgtt gtttaatcaa attgcaagca ataaacgaaa
    14161 aacctggatt ttgttgctgg tatttttcct actcttagct cttgttggtt atgcggttgg
    14221 ttatctcttt ataagatctg gacttggtgg tttggttatc gcactgatta tcggctttat
    14281 ctacgctttg tctatgattt ttcaatcgac agagattgtc atgtccatga atggagcgcg
    14341 tgaggtggat gagcaaacgg caccagacct ctaccatgta gtggaagata tggctctggt
    14401 cgctcagatt cctatgcccc gtgttttcat cattgatgat ccagccttaa atgcctttgc
    14461 gacaggttct aatcctcaaa atgcggctgt tgctgcgact tcaggtctac tagctatcat
    14521 gaatcgtgaa gaactagaag ctgttatggg acatgaagtc agtcatattc gtaattatga
    14581 tatccgtatt tcgactattg cagttgccct tgctagtgct atcaccatgc tttctggtat
    14641 ggcaggtcgt atgatgtggt ggggtggagc aggtcgcaga cgaagtgatg atgaccgaga
    14701 tggaaatggt cttgaaatca ttatgctagt ggtttcccta ctagctattg tactggcacc
    14761 tctcgctgca accttggttc agctcgctat ttctcgtcag agggaatttc tggcagatgc
    14821 atctagtgtt gagctgactc gcaatcccca gggaatgatt aatgccctag ataagttgga
    14881 caatagcaaa ccgatgagtc gccacgtcga tgatgctagc agtgctcttt atatcaatga
    14941 tcccaagaaa ggtggggggt tccaaaaact cttttatacc cacccaccta tctcagaacg
    15001 gattgaacgt ttaaaacaga tgtaaaagaa tccagaggtc gtctctggat ttttgctatg
    15061 ttgcaaattt ataaatcttc taaattaact agcttcaaac cgtgttctgt catgcgatag
    15121 atgatcgagc agacttcttt taagaaacga cggtcatgcg aaacagtgat gagaccgcca
    15181 ggataagtgg caaagagttt tctgatttgg ggttgagaag tgggagaaaa gtttcgtgtg
    15241 ggttcatcca gcaggagaaa gtttggtttg cgcaggacta aatccaaaag caggagtttt
    15301 ccctgttgtc cgccagataa ggagcgaatt tgatgctgca tttctggata actgaaattg
    15361 agactagcta ggtgagattg gattttctgt agttcctctt tttccccagt tttactgaga
    15421 taggctattg gggataaatc caattgcagt tttttgtggt aatcttgtgg cataaaacca
    15481 agtgaaatct ctcttttatc attcagaagt ctctgtaact tggctaacag agttgatttc
    15541 ccaacaccat ttggcccgat aataccgatt ttttcttggc cacggacagt tagttgtagt
    15601 ttttgaacca aaactcggtc gtcaatggac aaattttctt tttccagttg gactaagact
    15661 ttagaagctg gtaatggttg gatgtctgaa aagaaaagtt ggatttgttc ctcttcaagt
    15721 ggcttttgag tcatggactg agctgccttt tcgtagcgtt tttcttgtga gaggacagtt
    15781 ttcatctttt tagccaatag gcgaccggca gtactatctt tggtagctcg aagcgcagtt
    15841 tctacatttt gcttgactct ccgatgtttt ttcatggttt tatcgtaggc tctttggttg
    15901 ttagcagctt gctgactttg tttggcaaaa ttagcctttc tctgctcact atagctatca
    15961 tagtctaaat gctctactag cgtttccgct tctttacggt gtttgaccag tcgcaagtga
    16021 acaatagtgt ctgccgtttc agaaagaaag tcttcatcat gggaaatgaa aataacggtt
    16081 tgcctggtct tttgaatctg gccttttagc caatcaactg tctcaaggtc taggtcattt
    16141 gaaggttcat ctaaaaatag aatctcaaag ggtttggcta actcatggat aagctgaatt
    16201 ttcaaagctt cgccccctga tagattgcca atctcttggt cacttgcgaa acgattgcta
    16261 tcaaaatgca attcctccgc caaacgatag aggatactgt agtctaaatc aatagaatct
    16321 aaaaagaagt agtcgtgtaa agttttcttt tttaggtcct cagggacttt ttgaggaatg
    16381 taggccagtg actgataatc agactggatg tctcccttga tagtgaaatc agacaaatct
    16441 tcccccatta aagttttaag taaggttgat ttaccatttc cttcttcgcc aataatagct
    16501 accttttccc cgtcttggat ggtcatggtt aggtcagaga caaggtctcg taaatctttg
    16561 ttttgtgtga tggtcaggtg attgattttt atcatactat tgccctttct agaatgtcga
    16621 tagtacataa caaaaagctc tactttacct agtagagccc aaagtctatg tcaaaaaaac
    16681 tctattaaca tgccagaaaa agagcataaa agagcacaca aaaagagaca aaaacaagat
    16741 ctactaaata aaggttcttt atttgataga cttagttgtt catgtctccc ttacctccga
    16801 gtattagtat ctttatacta tacttttaag gaaattttgt caacagaaaa ctggaaattc
    16861 tatgctctaa aatccaaaaa caggtccata gagacttagt acgtgtttga catgctcgta
    16921 atggatttta tcatagtttc gccaagcagt gcgtgcttga tcgtttagtt ttaggctacc
    16981 cagtccaatc agaggactgg tgggttggta aaatttctca agatcaatta agatactgtt
    17041 gttcaacttt tccgtttttt tgagctcttg catagtagtg tttagcagct cttgtagtcg
    17101 aatatcatct gccgtaccct gtttacagtt ttggtagctt ttatttaact tggataggag
    17161 ttgaatgagt ttcttgtctt ccatgtcttc catatgagca tcctccttga tctgatgtac
    17221 tctttcccta tagtatagca ctaaaaaata aaactgtcat agtaaatatg ttaaaatttt
    17281 gaattttaat tacaaagttt ggtgtgctga tttgtagcct tttcatggta taatcaagag
    17341 agtaaatctt tatggaggaa gtatgaaatt aaatattcaa gaaattcgta agcagtctga
    17401 aggtttgaac tttgaacaaa cgttagattt agttgatgat ctgcgtgcac gtaatcaaga
    17461 aattttagat gtaaaagata tccttgcagt tgggaaagta caatatgaag accgtatgta
    17521 tttcttagat tatcaactat cttataccat tgttcttgct tcgagtcgca gtatggagcc
    17581 agttgagtta gttgaatctt atccagtcac ggaagttttc atggaaggcg caactaacca
    17641 gctagatcaa gaagttttag atgatgactt ggtcttgccc atcgaaaatg gggagcttga
    17701 ccttgctgag agtgtatcag acaatatcct gctaaacatt cctatcaagg tcttgacggc
    17761 tgaagaagaa gctggtcaag gatttatctc aggaaatgac tggcaaatca tgacagagga
    17821 agaataccaa gctcaaaaag cagtaaagaa agaagaaaac agtccttttg ctggcttaca
    17881 aggactattt gacggagatg aataatggtc ttgtcaaaaa aacgagcacg aaaggtgcta
    17941 gaagaaatca ttgccctctt cccagatgcc aagcctagtc ttgattttac caatcatttt
    18001 gaactcctgg ttgcggtcat gttatcagcc cagacgacag atgcagcggt aaataaggcc
    18061 acaccaggtc tctttgttgc ctttccaaca ccccaagcta tgtctgtagc gacagagagt
    18121 gagattgctt cacatatttc tcgcttggga ttgtatcgga ataaagctaa attccttaaa
    18181 aaatgtgccc aacagttact agacgatttt gatggtcaag tccctcagac acgtgaagaa
    18241 ttggagagtt tggcaggtgt tggtcgcaag acagccaatg ttgtcatgag tgtaggattt
    18301 gggattccag cctttgcagt ggatactcat gtggagcgta tttgcaaaca ccacgatatt
    18361 gtcaaaaaat cagcgacgcc acttgaggtg gaaaagcggg tcatggatat cttgccgcct
    18421 gagcagtggt tagctgccca tcaggccatg atttattttg gaagagccat ttgccatcca
    18481 aaaaatccag agtgtgacca gtacccacaa ttatatgatt ttagcaattt gtaagatact
    18541 acattgaaac tttttgcttg attttaagca tgctttgtgc tatagtaaat gataactaaa
    18601 tattccttta aacctgtccc gtgaggcagg caaggagcgc gataaagtag aagggtgaag
    18661 tctatactgt gtgcagtagg gctcgcttgg ctataaattt caagtctcct tgtttaagga
    18721 gacttttctt tttggaggtt tgtcatgaaa acaaaagaag ttgtagacga attgaccgtc
    18781 aaacgagcga ttacgcgtat tacttatgag attatcgaac gcaacaaaga tttgaataag
    18841 atcgtcttgg ctggtattaa aactcgtggt gtctttattg cccaccgaat ccaagaacgt
    18901 ttgaagcagt tagaaaatct ttcagttcct gttgtggaat tggatactaa acctttccgt
    18961 gatgatgtta aaagtggaga agatacttct ttggtttctg tcgatgtgac agaccgcgaa
    19021 gttatcttgg tggatgatgt gctctataca ggtcgtacca tccgtgctgc tattgataat
    19081 attgtcggtc atggtcgtcc tgcgcgtgtg agtttagcag ttctagtcga tcgtggacat
    19141 agagaattgc caatccgtcc agattacgtt ggaaaaaata tcccaaccag tcgttctgaa
    19201 gaaatcatcg tagagatgac agaacttgat gaccaagaca gagttctgat tactgaagaa
    19261 gcttagaaag ttaaaggagt agccatgtca gaaaatcaac aagcattgaa ccatgtggtg
    19321 tccatggaag acctcactgt cgatcaagta atgaaattga ttaagcgagg aattgagttt
    19381 aaaaatggag cccagcttcc ctatgaagac catccgattg tttccaatct cttctttgag
    19441 gattctacac ggacacataa gtcctttgaa gtcgcagaga ttaaacttgg attggaacga
    19501 cttgactttg atgtgaagac tagctcggtt aataagggtg agacacttta tgacaccatt
    19561 ttgactctgt ctgctttagg agtggatgtc tgtgtgattc gccatccaga ggtcgactac
    19621 tatagagaat tgattgctag tccaacgatt acgacttcca tcatcaatgg tggagatggt
    19681 tcgggccaac accctagcca gagcttgctt gatttgatga ccatttatga ggaatttggc
    19741 cactttgagg gtcttaaagt tgctattgca ggtgacttgg accactcacg cgttgccaaa
    19801 tccaatatgc agattttgaa acgcttggga tctgaactct ttttcgctgg acctgaggaa
    19861 tggagaagtc aagagtttgc agactatgga aagtttgtaa ccattgatga aatcattgat
    19921 caggttgatg tcatgatgtt tctccgtgtg caacacgaac gccatgatag tggagctgta
    19981 ttttcaaaag aagactacca tgcccaacat ggcttgactc aagaacgtta cgatcgtttg
    20041 aaagaaacag caatcctcat gcacccagct ccaatcaatc gtgatgtaga aatagcagac
    20101 cacttggttg aagcaccaaa atcacggatt gtccaacaaa tgaccaatgg tgtctttgtt
    20161 cgaatggcaa tcttagaatc cgtactagcg agtagaaacg ccaactaaaa cacaagacgt
    20221 taaaagacgc cagtgagcgt ccacgagagg tgaaaatatg acaaaaagaa ttctagtatt
    20281 agaagatggc acagtttttg aaggcaaggc cttcggagca gatattgatg taacaggcga
    20341 aatcgtcttt aatacaggga tgaccggcta ccaagaatcc attacagacc agtcttataa
    20401 tggacaaatc ttgaccttta cttatccttt ggtaggaaat tatggtatta atcgtgatga
    20461 ttatgaatcc attattccaa cttgtaaggg agtcgttgtt tttgaagaag cgcgtagagc
    20521 tagcaactgg cgcaaccaaa tgaccttgga tgaatttttg aaagccaaga aaattccagg
    20581 gatttcagga attgatacgc gtgctcttac caagattatc cgtaagcatg gtactatgcg
    20641 tgcaaccttg acccatgttg gggacagtat ggaccatgtg acggaccagc tccaagcaac
    20701 agttttaccg acagacaata tcaaacaggt ttctactaaa acgtcttatc cagctccagg
    20761 agttggtttg agcgtggtgc tagtggactt tggtctcaag cactcaatcc tacgtgaact
    20821 ttctaaacgc aactgtaacg tgacagttgt tccttattcg acaacggctg aagaaattct
    20881 ccatctcaat cctgacggag ttatgttgtc aaatggtcca ggtaacccag aagacgttcc
    20941 acaagcactc gacatgattc gcggtgtaca aggaaaaatt ccaatctttg gtatttgtat
    21001 gggacaccaa ctctttgcaa tggcaaacgg ggctaagacc tataagatga agtttggcca
    21061 ccgtggattc aaccatgcgg tacgtgaaat cgcaacagga cgagtagact tcaccagcca
    21121 gaaccatggt tatgcagtca gccgcgagga tttgccagag cacttgatta ttacccacga
    21181 agaaatcaat gacaagtcag tggaaggtgt gcgccacaga taccaacctg ctttctctgt
    21241 tcaataccac ccagatgcag ctcctgggcc acacgacgct agctacctat ttgacgagtt
    21301 tatcgagatg atggaagttt ttaaacaatc aaactaagaa cgagtaaaag ctcgtcggag
    21361 aatttatgta actgaacacg gacggaaagc tcagaatgta gagaaaccaa cttggattgt
    21421 caatccttcc ttgatttcct aaaattcaat cgctttctat tcgtcctttg tatcttattt
    21481 aatgtcgccc tgagaggcga cgaatagaaa ggagaagggt gctccgtatt tgctgaactg
    21541 aatacgggct acggacggtg ctaaaaagat agttattcct agaactgaca gttcttcgtc
    21601 ataactccta ttttagcttt gtccgcttga cacccttaat atcttatata tgcctaaacg
    21661 tactgatatt caaaaaatta tggtgattgg ttctggtccg attattattg gtcaggctgc
    21721 tgagtttgac tacgctggga ctcaggcttg cttgtcgttg aaagaggaag gttatgaggt
    21781 tgttttggtt aactcaaatc ctgcaaccat catgacggac aaggaaattg ctgacaaggt
    21841 ttacattgaa ccgattacac ttgagtttgt gacacgtatt cttcgtaagg aaggtccaga
    21901 tgccttgcta ccaacactcg gtggtcagac aggtctcaac atggccatgg aattatctaa
    21961 aaatggtatc ctagacgagc ttggcgttga acttctgggt accaaattat ctgccattga
    22021 ccaagcggag gaccgtgacc tctttaaaca attgatggaa gagcttgaac aacccattcc
    22081 agaatctgaa attgttaaca cagtagaaga agcagttgcc tttgcagcga caattggcta
    22141 cccagtcatc gttcgtccag cctttaccct tggtggtact ggtggtggta tgtgtgccaa
    22201 cgagaaagaa ttgcgtgaaa tcactgaaaa tggtttgaaa ttgtcacctg ttacccaatg
    22261 tttgattgag cgttcgattg ccggtttcaa ggaaattgaa tacgaagtga tgcgtgactc
    22321 agctgacaat gccttggttg tttgtaacat ggaaaacttt gacccagttg ggattcacac
    22381 aggggattcc attgtatttg cccctgcgca aaccatgtca gactatgaaa accaaatgct
    22441 tcgtgatgcg agcttgagca ttattcgtgc cctcaagatt gaaggtggat gtaatgttca
    22501 gctagctctt gatcctaaca gcttcaagta ttatgttatc gaagtaaacc ctcgtgtatc
    22561 acgttcgtca gcccttgctt ctaaagcgac aggatatccg attgctaagt tggctgccaa
    22621 gattgcagta ggtttgacct tggatgaggt tataaaccca gttacaggtt caacctatgc
    22681 catgtttgaa ccagcccttg actacgtagt tgctaagatt ccacgtttcc catttgacaa
    22741 gtttgaaaag ggtgaacgcc gtctcggtac acaaatgaag gcgactggag aagtcatggc
    22801 aattggtcgt aacatcgagg aatctcttct caaggcctgc cgctcccttg aaattggggt
    22861 gcaccacaat gaaatacctg aacttgcagc agtttctgat gatgccttga ttgaaaaggt
    22921 tgtcaaagcc caagatgacc gtctcttcta cgtatcagaa gccattcgtc gtggctacac
    22981 acctgaagaa attgcagagc ttacaaaaat tgatatcttc tatcttgata aactcttgca
    23041 tatctttgaa attgagcaag aattgggtgc tcatccacaa gatttagaag ttttgaaaac
    23101 agccaaactt aatggttttt cagaccgtaa gattgctgaa ctctggggaa cgactgatga
    23161 taaagttcgc caacttcgct tggaaaacaa gattgttcca gtttataaga tggtagacac
    23221 ttgtgcggca gagttcgact ccgaaacgcc atatttctat tcaacctatg gttgggaaaa
    23281 tgaatctatc agatctgata aagaatctgt acttgtccta ggttcaggtc caatccgtat
    23341 cggtcaaggg gttgagtttg actacgcaac cgttcactct gttaaggcta tccaggcagc
    23401 tggttatgaa gctatcatca tgaactcaaa cccagagacc gtttcaacag acttctctgt
    23461 atcagataag ctttactttg agccattgac attcgaagat gttatgaacg tcattgactt
    23521 ggaacaacca aagggagtta tcgttcagtt cggtggtcaa acagccatca accttgcgga
    23581 gccattggca aaagcaggtg tgaccatcct tggtacacag gttgctgacc tagatcgtgc
    23641 cgaagaccgt gacctcttcg agcaagctct caaagaattg gatattccac agccaccagg
    23701 acaaacggct accaatgaag aagaagcagc tcttgcagct cgcaagattg gcttcccagt
    23761 tcttgtccgc ccatcttatg tacttggtgg acgtgccatg gaaatcgttg aaaacgaaga
    23821 agaccttcgt tcttacatgc gaactgctgt taaggctagt ccagaccacc cagttcttgt
    23881 cgactcttat atcgttgggc aagagtgcga agttgatgcc atttcagatg gtaaaaatgt
    23941 actcattcct ggtatcatgg agcatatcga acgtgctggt gtccactcag gtgactcaat
    24001 ggctgtttac ccaccacaaa ccttgtcgca aaaggttcag gagaccatcg cagactacac
    24061 caaacgctta gcaatcggtc ttcactgcct tggaatgatg aacatccagt ttgttatcaa
    24121 ggatgaaaaa gtctacgtta ttgaggtcaa tccacgtgcc agccgtactg ttccattcct
    24181 atctaaggta accaatattc ctatggctca agtagcgacc aaactcattc ttggtcaaag
    24241 tttatcagaa cttggctacc aaaatggact ttaccctgaa agcacccgtg ttcatatcaa
    24301 ggcacctgtc ttctccttta ccaaactagc taaggtagac agcttgctcg gtcctgaaat
    24361 gaagtcaaca ggtgaagtta tgggttctga tgctactttg gaaaaagctc tctataaagc
    24421 ctttgaagct tcttatctac acttgccaac ttttggtaat gtcgtcttta ccatcgctga
    24481 tgatgccaaa gaagaagcct tgaacttggc tcgtcgtttc caaaacattg gttatggaat
    24541 ccttgcgaca gaagggacag cagccttctt tgctagtcat ggcttgcaag cccaacctgt
    24601 tggtaagatt ggtgatgacg ataaggatat cccaagtttt gtacgcaaag gaagaattca
    24661 agctatcatt aacacagtag gaacaaaacg aactgctgac gaagatggtg agcaaattcg
    24721 tcgttcagcc attgaacacg gggtgcccct cttcacagcg ctagatacag ctaatgccat
    24781 gcttaaggta cttgaaagtc gtagctttgt tacagaagcg atttaaatag aaaaataaga
    24841 tatagcagac tgaatttaga acagtacaca ggaatactaa aatatttcta taaattaatt
    24901 tgaattttct aattgatttg ttcgcatctt atttcaatct actatagaaa aaagtcttta
    24961 aaattataaa acgcatcata tcaagatttt tcaaaaacct tgatatgatg cgttttattg
    25021 tgggaatatg tatttcattt tctactaaaa ttatgttttt gaataacctc tatcttagta
    25081 gtttgtataa tccccctcaa tcagtttttg cgataagctt taatgctatg actataccac
    25141 tcttgcattt cttttgatgg tggtgttata taatcgccat acatctgggt taaaaattgg
    25201 tcatattttt tgggaacagg caacatacgg ccctcaaact cagttaaaat cagttcttta
    25261 aaggtatcaa ctgggaagat ttctttcatc ccttccttac cgatcccaac tcctccttca
    25321 tattgaggag tgttggttac agcatttttg actagttgat caattttctt gtaaaagtag
    25381 cgaggattga caaatcggag agcgtaccag ctacataatc taagaaaatc ttttagtttg
    25441 ctatcaccgt gaactgctcg tgattttttg atataagcta gttgacgaag agccacatac
    25501 ttatagctct tgtcgacaat gctcaagtct gtaaatcgat caattgggaa gacatcgatg
    25561 aaaaggctgg tatcatgacg cttgtactta acatggtctt ctataacagt agaagtgtcc
    25621 aaaatcgatg cgaaattatg gaagtaccaa gaagatgtat cgtaggaaag aaccttgtag
    25681 cgagggtgat tttcttcttc aataatcttc agtaaacgct cataatcctc acgataaagg
    25741 gaaatatcaa tatcatcatc ccaaggaatc atacctttgt ggcggatggc tccaagcatg
    25801 gttccataac tgagaaaata aggaatatca tatttcttac aagtctcatc aatatagtcc
    25861 agcagggcta gttgaatttc tttaatttct tttttttcta aatattgcat cctaatcctc
    25921 caatttataa gcgtgaaatt catgactgta gaagcgtttt tcttctggtg gtagggtcat
    25981 ataatctcca taaaattgtg tcaaaatagt atcaaatttt tcaggtgcag gaaggcttaa
    26041 attctcaaag ggtaaatcga ttgttttatc aaaggtacca cttgggaaga cttccttttc
    26101 cttaaatttt gaagggataa aagccatata ttgcccattt tcacgactat atttttgaat
    26161 ttctttctcg attttatttg caaaataacg aggagaaacc ggtcgaagga gtaaccagaa
    26221 ggctgttcgt atccaatctt ttaaaaggct atccttatag acaatatttt tatgtttact
    26281 gaaagacagc agtttgaagc tttccagttt ataacaagta tcaatgacct taggatcatc
    26341 aaagcgatct atagggaaaa tatcgataaa gataccagac tcataggttt ttgtatttcg
    26401 agtatcaata attttagtcg tactgtcggt tatcttgata aagttgttaa agtagttctt
    26461 atcagtttct aaggatagga gcttatactt gcttttttcc ttttgaaaaa tgttaataaa
    26521 tcgttggtag tcttctctag gcatggataa atcaatatcg tcgtcccaag ggataaagcc
    26581 ctcatgtcga accgccccaa tcagagtacc gtagttaata atatagttga tattgtgctt
    26641 tttacagaga gtatcaatat aatccaaaat ttctaattca atttgtttgg catcttcaat
    26701 ggttagttgt ttcattttaa actcctatga ttttttgaat ttatttttta aggctaggac
    26761 atggtttaaa aattcataga aaatgctatc ttttgtgaag acaagtagac taatataaga
    26821 gatagctgat agcaagacaa tcaaaccagt attaattaaa aatggcaaat taatgaccat
    26881 atccacagga tacacgaaat taatcaggaa ataaattgct acaaaggaaa gtgaaaagag
    26941 agagtatcga acagtatagc taaagatatg tcccaagtgg atgagttgtt ttctatggat
    27001 gaaaataata tagaaaacaa gtagagaagt ctctgataac atagttgtca gtaagtagta
    27061 ttcaggaacc acgatatggt tgaaaaagag gagactattc aagcccaaat tgagtagccc
    27121 agcaaagact gtatagactg tgatacgttt ttcatagcca ttggtaaaga gaatttggga
    27181 accaagaatg gtatctaagg ccaggataat cgtacgaaaa gcgaagagag aggtcaagat
    27241 gccgcctccg atatattttt cactaccgta aagtaggatg gcatttggtc ctaaaaccat
    27301 gagtccaaaa ctcagtggaa tgataaagaa gttaaagatt cgactacctc tattaaccag
    27361 agaaacatag gcttctttgt ctcctttccc cagatagtaa ctgagacgag gcacactcac
    27421 tccaattgca cctgttacaa ccccagctat aacggtcaca attcgctgag ctatggtata
    27481 gtaactaacg ttgacatcaa tccctgtttt aacgaggaag aggcgatcta aaaaagtgaa
    27541 gagcatattg gcattggcaa agactaacat ggctgtcaga gggagaaaga gtggtttaaa
    27601 atcacttagg tgaatcttaa caagtttgat gtctctttta atccaaaaat aactaatcag
    27661 gtagttaatc agcgtcgata aactcatcac aagtgtatag acaacaatat cgtgttcatt
    27721 tttaacaaat aagaaaatag agaccagcat caggatacgg atgaaggcag ttttgtaaaa
    27781 gagaaaactg taattttcca gagcttcatt gacccattcg attgaaaaaa tctgggcaat
    27841 gagttgaatc cccataacaa ggtagacctt tttgacgatt ggattatcaa taaagaagag
    27901 aggataggct aggatataga cagcagtggt caaaatcgta caagcgatgc acaaataaaa
    27961 aagactagaa aaggttctgt taagatcttt tttgttatcc ttgacattac tgatagccct
    28021 taaaccgtag ttatagacac cataagttgc aaagggcaag aaaaatgaca aaatagtgtc
    28081 gactgagttg aagtaaccat agtcagttcg gtccaagaca cgcgcgacat aggttccagt
    28141 taggatggga aaaataatat tcaagacacg aattcccatg taagatagag catttaattt
    28201 tatacttttc attcaattta cctcgttttt cattatatca taaagttagc taataagaaa
    28261 tgaagggcag taagtcaagt aatcactttg aagtttcaaa tcttaagttt taagttttct
    28321 ttaaggaaag tatattattc tgaaggactc taaaatttcg cagccattta ttagtaattg
    28381 ctacagaatt cctagtcatt actagaaatg gactagtttc tttgaataat agaactgcat
    28441 aattctccta ttctagaagg ggaggaccag tatttctttt atgataggac tagattgtgg
    28501 tataatagag agaataagtt tttttagtaa gacaaaggag aaaatagatg atttatgcag
    28561 gaattcttgc cggtggaact ggcacacgca tggggatcag taacttgcca aaacaatttt
    28621 tagagctagg tgatcgacct attttgattc atacaattga aaaatttgtc ttggagccaa
    28681 gtattgaaaa aattgtagtt ggtgttcatg gagactgggt ttctcatgca gaagatcttg
    28741 tagataaata tcttcctctt tataaggaac gtatcatcat tacaaagggt ggtgctgacc
    28801 gcaatacaag tattaagaaa atcattgaag ccattgatgc ttatcgtccg cttactccag
    28861 aggatatcgt tgttacccac gattctgttc gtccatttat tacacttcgc atgattcagg
    28921 acaatatcca acttgcccaa aatcatgacg cagtggacac agtggtagaa gcagttgata
    28981 ctatcgttga aagtaccaat ggtcaattta ttacagatat tccaaatcgt gctcaccttt
    29041 atcaaggaca aacacctcaa acattccgtt gcaaggactt catggacctt tatggatctc
    29101 tttctgatga agagaaggaa atcttgacag atgcatgtaa aatctttgtg atcaaaggaa
    29161 aagatgtggc cttggccaaa ggtgaatact caaatctgaa gattacaacc gtaacagatt
    29221 tgaagattgc aaaaagtatg attgagaaag actagtaaaa tgattaatca aatttatcaa
    29281 ctaactaagc ctaagtttat caatgtcaaa tatcaggaag aggctattga ccaagagaat
    29341 catatcctta tccgtcccaa ctacatggct gtctgtcatg cggatcagcg ttactatcag
    29401 ggaaaacgtg atcccaagat tttgaataaa aagcttccaa tggcaatgat tcacgagtca
    29461 tgtggaaccg tcatttctga cccgaccgga acctacgagg ttggtcaaaa agttgtcatg
    29521 attcccaatc agtctcctat gcagagtgat gaagaattct atgaaaacta catgacaggg
    29581 acccatttct tgtctagtgg atttgatggc tttatgagag agtttgtttc tctccctaaa
    29641 gatcgtgtgg tggcttatga tgctattgaa gatacggttg cagccattac agagtttgtc
    29701 agtgtgggca tgcacgctat gaatcgtcta ttgactcttg ctcatagcaa gcgggagcgg
    29761 atcgccgtta ttggagatgg aagtttagct tttgtggttg ccaatattat caactatact
    29821 ttgccagaat cagagattgt ggttattggt cgtcattggg aaaagttgga actcttctca
    29881 tttgccaaag aatgctatat tacggataat attcctgaag agttggcctt tgaccatgct
    29941 tttgaatgtt gtggtggtga tggtactgga ccagctatta atgacttgat tcgctacatt
    30001 cgtcctcagg gaacgattct catgatggga gttagcgaat ataaagtcaa tctcaatact
    30061 cgcgatgcct tagaaaaggg cttgattttg gttgggtcat ctcgttctgg tcgcattgat
    30121 tttaaaaatg ctatccaaat gatggaagtc aagaaatttg ccaatcgtct taaaaatatc
    30181 ctttatctag aagaacctgt aagagaaatt aaagatattc atcgtgtctt tgcaaccgat
    30241 ttaaacacag cctttaaaac agtgtttaag tgggaagtat aagtactgga ggttaattgt
    30301 ggagaaaatc attaaagaaa aaatttcttc cttacttagt caagaagagg aagtcctcag
    30361 tgttgaacaa ctgggtggaa tgaccaatca aaactatttg gccaaaacaa caaataagca
    30421 atacattgtt aaattctttg gtaaagggac agaaaagctt atcaatcgac aagatgaaaa
    30481 gtacaatctt gaactactaa aggatttagg cttagatgta aaaaattatc tttttgatat
    30541 tgaagctggt atcaaagtaa atgagtatat cgaatctgcg attacgcttg attcaacgtc
    30601 aatcaagacc aagttcgaca aaattgctcc aatattacaa actattcata cgtctgctaa
    30661 ggaattaaga ggagaatttg ctccttttga agaaatcaaa aaatacgaat ccttgattga
    30721 agaacaaatt ccttatgcca actatgaatc tgttagaaat gcagtcttct ccttagagaa
    30781 aagactggct gacttaggtg ttgacagaaa atcttgtcat atcgatttgg tgcctgaaaa
    30841 ctttatcgaa tcacctcaag gacgacttta tttgattgac tgggaatatt catcaatgaa
    30901 tgatccaatg tgggatttgg ctgccctctt tttagagtct gaattcactt cccaagagga
    30961 agaaactttc ttatctcact atgagagtga ccaaacaccg gtttctcatg aaaagattgc
    31021 tatttataaa attttacaag atactatttg gagtctatgg actgtctata aggaagagca
    31081 aggtgaagat tttggtgact atggtgtgaa tcgttaccaa agagctgtta aaggtttggc
    31141 ttcttatgga ggttcagatg aaaagtaaaa acggagttcc ttttggcctt ctctcaggta
    31201 ttttctgggg cttgggtcta acggttagtg cttatatctt ttcgattttt acagatttgt
    31261 caccctttgt ggtggctgca gctcatgatt ttttgagcat ctttatctta ctagcttttc
    31321 tcttggtaaa agaagggaaa gttcgcctct caattttctt aaatattcgc aatgtcagtg
    31381 ttatcatcgg agccttgcta gcaggcccta tcggtatgca ggccaatctt tatgcagtta
    31441 agtatatcgg aagttcttta gcttcatctg tatcggctat ttaccctgcg atttcagttc
    31501 tattggcttt cttctttttg aagcacaaga tttcgaaaaa tactgtattt gggattgtct
    31561 tgattattgg agggattatt gcccagacct ataaggttga acaggttaat tccttctaca
    31621 ttgggattct ctgtgctttg gtttgtgcta ttgcatgggg aagtgagagt gttcttagct
    31681 cctttgctat ggaaagtgaa ctgagtgaaa tcgaagccct cttaatccgt caagtgactt
    31741 cgttcttgtc ctatcttgtg attgtgctct tctctcatca gtcatttact gcagtagcca
    31801 atggacaatt gctaggtctc atgattgttt ttgcagcctt tgatatgatt tcctacttgg
    31861 cttattatat cgctatcaat cgcttgcaac cagccaaggc tacaggcttg aacgtgagct
    31921 atgtagtatg gacggtcttg tttgcagttg tttttttggg tgcaccgcta gatatgctga
    31981 ccattatgac gtcacttgtc gtcattgctg gagtttatat tattattaaa gaataaagga
    32041 gattcgtgtg aaagccatta tcttagcagc gggattggga actcgcttgc gtcctatgac
    32101 tgaaaatacc cctaaagcct tggttcaggt taatcaaaaa cctttgattg aataccaaat
    32161 tgagtttctc aaagaaaaag gaatcaatga catcatcatc attgttggtt atcttaaaga
    32221 acaattcgat tacttaaaag aaaaatacgg tgttcgcctc gttttcaatg ataaatacgc
    32281 tgactacaat aacttttact ctctctatct tgtaaaagaa gaattggcca acagctatgt
    32341 tattgatgct gacaattatc tctttaaaaa tatgttccgc aatgatttga cacgttcgac
    32401 ttattttagt gtttatcgtg aagattgtac caacgaatgg ttcttggtct atggagatga
    32461 ctacaaggtt caagacatta ttgttgatag caaggcaggt cgcatcctta gtggtgtatc
    32521 cttctgggat gctccaactg cagaaaagat tgtcagcttt atcgacaagg cttatgcaag
    32581 tggtgaattt gttgatctct attgggacaa tatggttaag gataatatca aagagctaga
    32641 tgtctatgtt gaagaattag aaggcaatag catttatgag atcgatagtg tccaagacta
    32701 tcgtaaatta gaagaaattc ttaaaaacga aaattaaaga ttccaacatc tgacaaaata
    32761 gtcggatgtt ttttgatttt ttacgaactt ttacgaatag atagatgagt agaaaaagaa
    32821 atggagttat ttatgaaaat cacaaactat gaaatctata agttaaaaaa atcaggtttg
    32881 accaatcaac agattttgaa agtgctagaa tacggtgaaa atgttgatca ggagcttttg
    32941 ttgggtgata ttgcagatat atcaggttgc cgtaatccag ccgtttttat ggaacgttat
    33001 tttcagatag acgatgcgca tttgtcgaaa gagtttcaaa aatttccatc tttctctatt
    33061 ttagatgact gttatccttg ggatttgagt gaaatatatg atgcgcctgt acttttattt
    33121 tacaagggaa atcttgacct cctgaaattc ccgaaggtag cggtcgtggg cagtcgtgct
    33181 tgtagcaaac agggagctaa gtcagttgaa aaagtcattc aaggcttgga aaatgaactg
    33241 gttattgtca gtggtctggc caagggcatt gacacagcag ctcatatggc agctcttcag
    33301 aatggcggaa aaaccattgc agtgattgga acaggactgg atgtgtttta tcctaaagcc
    33361 aataaacgct tgcaagacta catcggcaat gaccatctgg ttctaagtga atatggacct
    33421 ggcgaacaac ctctgaaatt tcattttcct gcccgtaatc gcatcattgc tggactttgt
    33481 cgtggtgtga ttgtagcaga ggctaagatg cgttcaggta gtctcattac gtgtgagcga
    33541 gcaatggaag aaggacgcga tgtctttgct attcctggta gcattttaga tggactatca
    33601 gacggttgcc atcatttgat tcaagaagga gcaaaattgc tcaccagtgg gcaagatgtt
    33661 cttgcggaat ttgaatttta aaaatgacct aagctagaat tctaagaaaa aatcaatttt
    33721 aagagaaaat gaacccaaca tttccataat aaaacgcata ttagcaagtt tttaacactt
    33781 gctaatatgc gttttttcta agtggattag tagagtagag gatttttctc atataatact
    33841 cttcgaaaat ctcttcaaac tacgtcagct tccatctgca acctcaaaac agtattttga
    33901 gctgagttcg tcagtcttat ctacaacctc aaagcagtgc tttgagcaac ctgtggctag
    33961 cttcctagtt tgcgctttga ttttcgttga gtataaggga aagtatagtg aattgaaata
    34021 agatgtgaac aactctatca ggaaagtcaa attaatttat agaaatattt tagcagccaa
    34081 ggtgcactgt tatagattca atacactata atttagtgta attgagaaag gagaaatgat
    34141 tgtgattgat gttggctagg ttatgttcaa tgattcctac catctcaaat cttgttagta
    34201 aggaaaaata aattcttcaa aagtagagat tacaaggctt gtttaagaaa gaattcaaag
    34261 accttgacaa ataaaaataa aatggttatt ataaaaaatg gtctgaaata gatgatgata
    34321 cttttcgaaa atctttttac gtcagctcag ctttgccttg ctgtgttttg agcaagctac
    34381 ggttagcttc cgagtttgat tttcatttac tagaaatgaa actgatgaga gatatcagta
    34441 gacatttgag tcaggatatt atggaaaatg ataaaaagag ctcgtgagat tggcatatca
    34501 gactactaaa gtattgagtt tgttaggatt ttagcgacta gttagctggg aaaggaagat
    34561 atttgtgaca aataataaac tgtattcgtt gatagaattt agaaataaaa tatatgaaga
    34621 attagaactt tccagaagtg atttagcgat tttactatgt gccatgctta tcgcctctat
    34681 cggattaaat atggattcga ctcccgtgat tattggagcc atgttaatct ctcctttgat
    34741 gacacctatt ctgggagtgg ggctctctct agctatattt gattttaaat tgttaagaaa
    34801 atcttttaaa atattagcta ttcaaattct tgccagttta atagcttcaa cactttattt
    34861 ttatctttct cccatttcgt atgctagttc ggaaattgtt gctagaacct ctccgactat
    34921 ttgggatgtt ctcattgctt ttgtaggagg gatagcaggt attattggtg ctaggaaaaa
    34981 agagaccaat aatattgttc ctggtgttgc tattgcaacc gccttgatgc ctcctctttg
    35041 tacagtaggt tatgctattg cttctgctaa tctaaaattt atcataggct cctcttacct
    35101 attcctcatc aattgtagct ttattgtcat tgcgacttat ataggtgtta ggttgatgat
    35161 ggttaagaaa cattatttta aagataatga agaagactct aaaatgcgta ggattttgct
    35221 tctagttgct gttttgctga tgattccgag tttcatctct gcaacgactt tagtgagaga
    35281 aacgttgaaa aaagagtccc ttaagaaatt tatatcagag cagtttcagg ggtataatat
    35341 tttgaaaaaa acctattcta aaaagactca taccctaaag ctaaccattt caggaaatta
    35401 tttgacagaa gaagaactcg atatgatttc aagtaagaga ggtgactatg gtttaagtga
    35461 tgtttctgtt caagtttcac aattgtctga ttcagaacaa cttagtaagg aagagctggt
    35521 ggagcatttc ttccagtata tcaaggataa ggaagcaaaa gaaaaggaga aagccaataa
    35581 atttgataca gagtctgagg agcaataatt tcttgagaat agctggtttc tctcgtgagt
    35641 cttctatgta tatcaaagga agactgaggt tttaagtata aaacttttct tctattatag
    35701 tagctaagtc ttgacagggt tcaaaaaatg gtttacactt tataaagttt attactttga
    35761 aaaggtgtga tactgtggct acggcaacaa aaaagaaaaa atcaacagtt aaaaaaaatc
    35821 tagtcatcgt ggagtcgcct gctaaggcca agacgattga aaaatatcta ggcagaaact
    35881 acaaggtttt agccagtgtc gggcatatcc gtgatttgaa gaaatccagt atgtccgtcg
    35941 atattgaaaa taattatgaa ccgcaatata ttaatatccg aggaaaaggc cctcttatca
    36001 atgacttgaa aaaagaagct aaaaaagcta ataaagtttt tctcgcgagt gacccggacc
    36061 gtgaaggaga agcgatttct tggcatttgg cccatattct caacttggat gaaaatgatg
    36121 ccaaccgtgt ggtcttcaat gaaatcacca aggatgcagt caaaaatgct tttaaagaac
    36181 ctcgtaagat cgatatggac ttggtcgatg cccaacaagc tcgtcggatc ttggatcgct
    36241 tggtagggta ttcgatttcg cctattttgt ggaagaaggt caagaagggc ttgtcagcag
    36301 gtcgcgttca gtccattgcc cttaaactca tcattgaccg tgaaaatgaa atcaatgcct
    36361 tccagccaga agaatactgg acagttgatg ctgtctttaa aaagggaacc aaacaatttc
    36421 atgcttcctt ctatggagta gatggtaaaa agatgaaact gaccagcaat gacgaagtca
    36481 aggaagtctt gtctcgtctg actagtaaag acttttcagt agatcaggtg gataagaaag
    36541 agcgcaagcg caatgctcct ttaccctata ccacttcatc tatgcagatg gatgctgcca
    36601 ataaaatcaa tttccgtact cgaaaaacca tgatggttgc ccaacagctc tatgaaggaa
    36661 ttaatatcgg ttctggtgtt caaggtttga ttacctatat gcgtaccgat tcgactcgta
    36721 tcagtcctgt agcgcaaaat gaggcggcaa gcttcattac ggatcgtttt ggtagtaagt
    36781 attctaagca cggtagcaag gtcaaaaacg catcaggtgc tcaggatgcc catgaggcta
    36841 ttcgtccgtc aagtgtcttt aatacaccag aaagcatcgc taagtatctg gacaaggatc
    36901 agctcaagct atataccctt atctggaatc gttttgtggc tagccagatg acagcggccg
    36961 tttttgatac catggctgtt aaattgtctc aaaaaggggt tcaatttgct gccaatggta
    37021 gtcaggttaa gtttgatggt tatcttgcca tttataatga ttctgacaag aataagatgt
    37081 taccggacat ggttgttgga gatgtggtca aacaggtcaa tagcaaacca gagcaacatt
    37141 tcacccaacc gcctgcccgt tattctgaag caacactgat taaaacctta gaggaaaatg
    37201 gggttggacg tccatcaacc tacgcgccaa ccattgaaac cattcagaaa cgttattatg
    37261 ttcgcctggc agccaaacgt tttgaaccga cagagttggg agaaattgtc aataagctca
    37321 tcgttgaata tttcccagat atcgtaaacg tgaccttcac agctgaaatg gaaggtaaac
    37381 tggatgatgt cgaagttgga aaagagcagt ggcgacgggt cattgatgcc ttttacaaac
    37441 cattctctaa agaagttgcc aaggctgaag aagaaatgga aaaaatccag attaaggatg
    37501 aaccagctgg atttgactgt gaagtgtgtg gcagtccaat ggtcattaaa cttggtcgtt
    37561 ttggtaaatt ctacgcttgt agcaatttcc cagattgccg tcatacccaa gcaatcgtga
    37621 aagagattgg tgttgagtgt ccaagctgtc atcagggaca aattattgag cgaaaaacca
    37681 agcgtaatcg cctattctat ggttgcaatc gctatccaga atgtgaattt acctcttggg
    37741 acaagcctgt tggtcgtgac tgtccaaaat gtggcaactt cctcatggag aaaaaagtcc
    37801 gtggtggtgg caagcaggtt gtttgtagca aaggcgacta cgaggaagaa aagattaaat
    37861 aagaggaggg gcccgaaagt aaatttcagg ctccttttgg ttagaacttg acaaaataca
    37921 tcattttatg cgaaactaga agaagattat tttatactca atgagaatca aagagcaaat
    37981 tagaaagcta gtcgcaggtt gctcaaagca ctactttgag gttgaagatg gaagctgacc
    38041 tggtttgaag agattttcga agagtattaa ctaggagaag ttatgcgtct tatctatcta
    38101 attattggtt ttttatcgct ggccttggct attgttgggg ttgttttacc cttgttgccg
    38161 acaacgcctt tccttttgtt gtctattgct tgtttctcca gaagttccaa gcgtttcgaa
    38221 gactggcttt atcataccaa gctctatcaa acatatgtag ctgattttcg cgagactaag
    38281 tctattacgc gtgaacgaaa gaaaaaaatc atcgtctcta tctacgtctt gatgggaatt
    38341 tctatttatt ttgcacctct tttaccagtc aaaatcggtc tgggtgcttt gaccatcttt
    38401 atcacttatt atctcttcaa ggtcattcca gacaaagaat agttaaaaca gtagttattt
    38461 gccttgataa aattgaaagc atattcataa caatatgata taataaattt gaagtaatat
    38521 tcaaggagaa tcaaatgatt tacgaatttt gtgctgaaaa tgtgacttta cttgaaaaag
    38581 cgatgcaggc tggagctcgt cggattgaac tctgtgataa tctagcagtt ggtgggacaa
    38641 cacccagcta tggagtgact aaggcagcgg ttgaactggc agctaactac gatacaacca
    38701 tcatgaccat gattcggcca cgtggtggtg actttgtcta taatgaccta gaaattgcta
    38761 tcatgctaga agacatttgt ttgactgctc aggctggaag tcaaggggtt gtatttggag
    38821 ctttaactgc tgataaaaag ttggataagc ctaatctgga aaagttaatt gctgcatcaa
    38881 aaggaatgga aattgtcttt cacatggcct ttgatgaact aagtgatgaa gatcaaccgg
    38941 aagctattga ctggctcagt caagccggtg tcactcgtat cctaactcgt gctggtgtgt
    39001 ctggcgactc cttagaaaaa cgttttgttc actatcacag aattttggag tacgctaaag
    39061 gtaaaattga aattctacca ggtgggggga ttgaccttga caaccgtcaa acctttattg
    39121 accaggtggg ggtaacacaa ttgcatggca ctaaggttgt tttttaaaaa atagaaagga
    39181 actgctagcc ttgggtagca gttttcactt atgtttgaaa tttttaaatc ctatcaattt
    39241 aatcaagaaa aggctcatga ttatggtttt atagaaaata gcgaagtctg gacatatagt
    39301 tgccagattt tgcaaggtga ctttgtcatg actgtgtcca tcactgctga taatgtgaac
    39361 tttcaagtct ttgaccaaga gactggtgac ctctatcctc acgttcatat ggaaagcatg
    39421 aggggaagtt ttgtcggaaa tgtccgtgag gcttgtctgg agattcttta ccagattcgg
    39481 aaggcttgtt ttgatgtgca agattttatc tgtcatcaga ctaagcgtat catgactcaa
    39541 gttcaggaaa agtatggaaa ccagttggag tatctgtggg aaaaatcgcc tgatacagct
    39601 gtattgcgcc atgaaggcaa tcaaaagtgg tatgccgtct tgatgaaaat ctcttggaat
    39661 aagctggaaa agggcagaga aggacaagtg gaagcagtca acctcaagca tgaccaagta
    39721 gctaatttgc tttcacaaaa ggggatttat ccagccttcc atatgagcaa gcgctactgg
    39781 attagtgtgt cccttgatga tactttatca gatgaagaag tactggaatt gatagaaaaa
    39841 agttggaact taacctctaa aaaatgaaat attttaataa ttttcatgaa ctttcaatta
    39901 gctaaatatt ctttactgaa gaaattttca gaaaatatag gatttaccac accagaggaa
    39961 tgtggtgcca tcttcaaata cctgattgag aatgtcaaga cggatcgtca gatcatctat
    40021 tcgcctcact gtcatgatga cctcggaatg gcagtggcaa atagccttgc tgctgtcaag
    40081 aatggtgcag gacgtgttga agggactatc aatggtatta gggagcgagc tgaaaatgct
    40141 gctttggaag aaattgcagt ggctctcaat attcgccaag attactacca agtagaaacc
    40201 agtattgtcc taaatgagac catcaatacg tcagaaatgg tttctcgctt ctctggtatt
    40261 ccagttccta aaaacaaagc cgtcgttggt ggcaatacct tctcccacga atctggtatt
    40321 caccaagatg gagtccttaa aaatcctctc acttatgaga tcatcacacc tgaattggtt
    40381 ggtgttaaga ttccgcttgg aaaattatct ggtcgccatg cttttgttga gaaactgaga
    40441 gaattggccc tagattttac agaagaggat atcaaaccac tctttgctaa gttcaaggca
    40501 ctggccgata agaagtaaga aatcacagat gcagatactc gagctttggt agctggaacc
    40561 atggttgaaa atccagaagg cttccacttt gatgatttac aacttcaaac tcatgcagat
    40621 aatgacattg aagcgctcgt tagcctagcc aatatggatg gtgagaaagt cgaatttaat
    40681 gcgacagggc aaggttccgt tgaagcaatc tttaacgcta tcgataagtt ctttaactaa
    40741 tctgttcgtt tggtgtccta cactatcaat gcggtaacag atggaatcga tgcccaggat
    40801 cgggttttgg tcactgttga aaacagagat acagaaacca tctttaatgc agcagggctt
    40861 gattttgatg tgttgaaggc ttctgctatt gcctatataa acgctaatac ctttgttcaa
    40921 aaagagaatg caggtgagat gggacgcagt gtttcttacc acgatatgcc tagtgtgtaa
    40981 aggagaaggc tatggcaaag aaaatagtag ctctagtagg agacggaatt ggcccagaaa
    41041 tcatggaggc tggtttagaa gttctggagg ctctagctga aaaaacaggt tttgactatg
    41101 agattgacag acgaccgttc ggaggtgcag atattgatgc agcaggacct cccttacctg
    41161 atgaaaccct taaggcaagt agggaagcag atgctatcct actagcagct atcggtagtc
    41221 ctcagtatga tggagcagcg gttcgccctg aacaaggcct gatggctctc cgtaaggaac
    41281 tcaatcttta cgctaatatt cgtcctgtaa aaatctttga cagtctcaag tatttgtcac
    41341 cactcaaacc ggaacgaatt tctggtgtag actttgtcgt ggtgcgtgaa ttgacaggcg
    41401 agatttactt tggagatcat attcttgaag agcgcaaagc gcgtgatatc aacgactata
    41461 gctatgagga agtggagtgg attattcgca aagcctttga aattgcaaga aatcgcagaa
    41521 aaatccttac tagtatcgat aagcaaaatg ttctagcgac ctcaaaactc tggcggaaag
    41581 tagctgagga agtcgcacag gatttctcag atgtaacctt ggaacaccag ctggtagact
    41641 cagctgctat gcttatgatt accaatcctg ctaagtttga tgttattgta acggagaatc
    41701 tttttggaga tattttatct gatgaatcaa gcgtcttatc tggtacactt ggggttatgc
    41761 catcagccag tcattctgaa aatggaccaa gtctctatga acctatttac ggttcagcac
    41821 ctgatattgc aggtcaagga attgccaatc ctatttccat gattttatca gttgccatga
    41881 tgttgagaga tagtttcgga cgttatgagg atgcagagcg tatcaaacgt gctgttgaga
    41941 caagtctggc ggcaggaatt ttaacgagag atataggagg tcaggcttca acaaaggaaa
    42001 tgacggaagc tattattgca aggttatgaa gttagacgaa aaaattactc tagtcctttt
    42061 gatttggaat gtcatcattt tcttgattta tggcattgac aaattcaagg caagaagaag
    42121 agcttggcgc atccaagaga aaatcttact cattttagcc cttacttgtg gtggttttgg
    42181 ggcctggtta gctggaatca cttttcacca caagactcga aaatggtact ttaaaacagt
    42241 ttggtttctt gggatggtga ccacactagt agccttatat tttatttgga ggtaatggat
    42301 ggcagggtct tcgagggaat acgctgcttg ggctctagcg gactatggtt ttaaggtcgt
    42361 gattgcagga tctttcggtg acattcatta caataatgaa ctcaataatg gcatgttgcc
    42421 aatcgttcag cctagagagg ttagagagaa actagcccag ctaaaaccaa ccgaccaggt
    42481 aactgtggac ttggaacaac aaaaaatcat ctcaccagtt gaagaattca ccttcgagat
    42541 agatagcgag tggaaacata aattcctaaa tagtttggat gatatcggta ttaccttgca
    42601 gtatgaagag ttgattgctg cttatgaaaa acaacgacca gcctactggc aggattagaa
    42661 aaaatagaaa aggaaatata gtaaactgaa ataagatgta aacaaatgaa ttggagctta
    42721 acatccattt ccagcaattt tttagaaact acagtggact attctggatt caacacatta
    42781 taaaattatg acaaaacaca ttcacaagaa ggctacgaca ttttaaaagg tgagggcgga
    42841 tgtatcgttt gccctactaa agttggttac attatcatga ccagcaacaa ggcaggactt
    42901 gagcgtaagt tcgcagccaa agaacgtaag cgtaacaaac caggtgttgt tctctgcggt
    42961 agcatggatg aacttcgcgc tttagcgcaa ctcaacccag aaattgaagc attctactaa
    43021 aaacattgga tgaagatatt cttcttggtt gtatccttcc ttggaaacca gaagcctttg
    43081 aaaaactcaa agcatacggg gatggccgtg aagaacttat gactgatgta cgtggtacta
    43141 gctgttttgt tatcaagttt ggaaaagcag gtgaacaatt ggctgccaag ctttgggaag
    43201 aaggtaaaat ggtctacgcc tcatatgctt caatgacaaa acgattgaaa ctcgctatga
    43261 gagcaaggtg taatggtgtc tatggtcgat aaggacggca aactcatccc agaacaagga
    43321 ggagcacgtt caacttcacc agcaccagtt gtgatccgta aagggcttga cattgataaa
    43381 atcatgatgc acctgtcaga tacttttaac tcatgggact accgtcaggt tgagtattat
    43441 taagataaaa aaagaagtct agtgttatga gatattaaag ctcctaacac tggacttttt
    43501 gtttagaatt tcttttcttt ttctatagga tatggtattc tatgtagaaa atatatgtta
    43561 ataagtaatg ccaatattta aacatcatta gtaaaaggag ttagattgat gaataaaaga
    43621 aaagttagtt tagaagattt ttataaatgg tatagtctaa ataaagaaga gttattaaat
    43681 aaggcaactg ttggtgaaaa gtttaatgat aaattaaaag aagagtttct ccaggaatgg
    43741 cctttggata ggattttaac aatgtcaatc gatgaatatg taataggaaa gggacagcaa
    43801 aataagtctt tatgctacgc tcttgagaag ggaaaataca aaaatctatt tcttggaatt
    43861 tctggtggct cagcttcaaa atttggtatt tattggaata aaaaaacaaa caaatataaa
    43921 gatcaagcta ataatgagat ttcagagttg gatcagcgat tttcaaaatt aaaatcagat
    43981 ttgtatgaaa ttatcaaaga aggtattcgt tttaactttg aaaattctat ttttgatatg
    44041 aaaagatcaa caaatgaatt tattggtcgt tctgctatgg tgacaaaatt actttgtatc
    44101 tattctgagg gagatccttt ctttggtgta aatattaata gtcagaaaga attttggaac
    44161 cactttgttt ctcagacaaa tcaaggtgga ccttatctgc aaaatcataa aataattgaa
    44221 ctggtgtcca aaacttatcc tgagttggag ccatcgaaat taggaactat gctttttgag
    44281 tattctaagc tttttatgga aaataaggaa gacaatagta caatggattc atcaaacaat
    44341 tttcgtcatc aattaactca atctctatta aagtctccaa acctcatcct tcgtggtgct
    44401 cctggcacag gaaagactta tcttgctaaa gaaattgcca aagaattaac ggatggcaac
    44461 gaagaccaaa tcggatttgt acaatttcac ccatcctatg attatacgga ttttgtagaa
    44521 ggtttaagac cagtatcaaa tggggatgga gctattgagt ttaggctaca ggacggtatt
    44581 tttaaagatt tttgtcagaa agcaaaagaa acccaattga ttggaggaca agataatttt
    44641 gatgaggctt gggattctta cttagaatat ataaatgttg ctgaagaaaa agaatatata
    44701 acaaaaacat cttacttatc tgttaatagt agacaaaatt tgtcagtaaa ttatgatagt
    44761 ggtgttccag gatggtcact acctagcaaa tatgtttacg agttgtataa agataaaaat
    44821 tataataagc aagaatacta caaaagtggt ggaaaaactg tcctagaaac attgagaaag
    44881 agatttggtt tgaaagacta tgtttcccca acagaaattg atactgataa gaaattcgtt
    44941 ttcatcatcg atgaaatcaa tcgtggggag atttctaaga tttttggcga actctttttc
    45001 tctatcgacc ctggctatcg tggtgaaaaa ggaagtgttt ctacccaata tgcaaatcta
    45061 cacgaaactg atgaaaagtt ctatatcccc gaaaatgttt acatcatcgg aactatgaat
    45121 gatattgatc gttcagtgga tacctttgat tttgctatgc gtcgtcgttt tcgttttgtt
    45181 gaagttactg ccgagggtca agttggcatg ttggataaag agttgaatat ccatgcagaa
    45241 gaagcaaaaa ttcgtctaag aaacttgaac gctgctatcg aaaatgttca ggaattaaac
    45301 agtcattatc atattggacc aagttatttt cttaagttga aggatgtaga ttttgactat
    45361 gaattactct ggtctgatta tattaagcct ctcctagaag actacttgcg aggttcttat
    45421 gatgaggttg aaactttgga aactttgaaa aaagcatttg aactgacaaa taatgatcaa
    45481 actggtcaac aagatactgg tgataatgat gcggattact gataatcaat acaagattat
    45541 taaagaaaaa tttgttgaag aatatcctaa actaagcaat cttcttttag acagaacctt
    45601 ggaaagtcta tcccaagatg aacgtatttt catttttcca aatgatttga ctcatactcc
    45661 tgatttggat aaggaccaaa agatttttga aacagtcaat cagaaaatca agacagggaa
    45721 cgtgattggt tttcttggat atggtcagga aagattaacg atttcctcac gattttctga
    45781 tgagagtaat gaccattttt tgcattatct cttaaacaag attcttcata tcaatctcac
    45841 tagtttagat gttgctttgt ctcgtgaaga gaggctttat caacttttgg tgtatctctt
    45901 tcccaagtat ctacaagctg ctattcgaaa aggtctttat aaggaatatc atcgattttc
    45961 tcataacgac agtaatgtta agggagtgat tgatgtaaga agccatctca agaaaaatct
    46021 tcctttcacg ggaaatattg cctacgcaac gagagagttc acctatgata atcccctcat
    46081 gcagttggtc cgtcacacta ttgaatacat taagaatcag aaaagcattg gtcaaggggt
    46141 actagataat ctctcaacta gtcgtgaaaa cgtatctgaa atcgtgcgtg taacgccctc
    46201 ttataaacta gctgatcgtg ctaagattat tcggggaaat caatctaaac ctatacgtca
    46261 tgcatacttt cacgagtaca gaaacttaca agaactttgt ctgatgatcc taaaccaaga
    46321 aaagcacggt ttagggtatc aagatcaaaa aatctatggt attctctttg atgttgcctg
    46381 gctttgggaa gagtatgttt acaccttgtt gccaaaaggt tttgtacatc ccagaaataa
    46441 ggataagacg gatggaattt cagtattttc tgttgggaaa cgaaaagtat atccagattt
    46501 ttatgacaga gaacgaaaga ttgttctaga tgcaaaatat aaaaaactgg aattgactga
    46561 aaaaggaatc aaccgtgagg acttattcca gctgatttcc tattcttata ttttaaaagc
    46621 tgagaaggct ggactgattt ttcctagtat ggagcagtca gtaaatagtg aaataggaaa
    46681 agtagctggc tatggagctc aattgaagaa gtggtctatt cgaatccctc agaatgcctc
    46741 attctatagt acattttgta aaatgatgga aaattcagaa gaaaatttta aagcgattat
    46801 tgatgaagaa gtggggagaa aataatttcc cctctttctt ttatttttaa cacaagtaaa
    46861 acccgaacga tatattttaa ttcataaaat aatttgacaa aaactgtact ttggtttata
    46921 ataaattaag gaaacgtcgg aaaaggcgta gtgatgcaag agcataggta ggtcattaca
    46981 aaagaaacga gacatcgata tgttaaatga atttccaatt tttgattacg aagatattca
    47041 attgattcca aataaatgtg tcattaaaag ccgtgcagaa gcggatacaa gtgtcacttt
    47101 aggaaatcac acctttaaac tacctgttgt gccagcgaat atgcagacga ttttggatga
    47161 aaatgtagca gagcaactgg ctaaaggtgg ttacttctac attatgcacc gttttgatga
    47221 ggcaggacgc attcctttta ttaaacgaat gcacgatcaa gggctcattg cttctatctc
    47281 tgtcggtgtt aaggattatg agtatgattt cgttagacag ctcaaggctg atgctcctga
    47341 gtatatcact attgatattg ctcatggtca tgcggatagc gtgatttcta tgattcaaca
    47401 catcaagaaa gaattgccag atacctttgt cattgctgga aatgtgggaa caccagaagc
    47461 tgtgcgtgaa ttggaaaatg ctggtgcgga tgctactaag gtcggaatcg gtcctggtaa
    47521 ggtttgtatc accaaggtta agactggttt tggtacaggt ggttggcagt tggctgctct
    47581 acgctggtgt gccaaggctg cgcgtaaacc gattatcgct gatggaggaa ttcgtactca
    47641 cggtgatatt gctaagtcta tccgcttcgg tgctagcatg atcatgattg gttccctctt
    47701 tgcaggacac attgaaagtc cagggaaaac gattgaagtc gatggtgaac agttcaaaga
    47761 atattatggt tcagcctcac aatatcaaaa aggtgcttac aaaaatgtgg aaggcaaacg
    47821 tatcttgctt cctgctaaag gtcatctgca agacacttta actgagatgg aacaagacct
    47881 tcaaagtgct atttcttatg caggtggacg tcaggttgct gaccttaaac acgttgatta
    47941 tgtgatcgtg aaaaactcca tctggaatgg ggatgcttcc cactaagacg gggtctttga
    48001 ccaaaaaact tgttattaga gcaaatttct gttataataa aacaagtttc cacccttagt
    48061 gtaatggata tcacgtaaga ttccggttct tgagatgggg gttcgattcc ctcagggtgg
    48121 atgtaaacat cctaaaaagc ctttaatagg gcttttttct ttatcctgac tcaaatttgc
    48181 cgctaaaact gagaatctct gtctaaagaa ttcccaaatg ctttccagtc ccgttttaga
    48241 gtgactcagg gggctttttt tgatataata aaaaggacta ttatcagtta gaaagaggtt
    48301 ggtatgaaag aattacaaac tgtactaaag aatcattttg caatcgaatt tgcagacaaa
    48361 aagttactgg aaactgcctt tactcatacg agttatgcca atgagcaccg cctcttaaaa
    48421 atttcacaca atgaacgctt ggaattttta ggagacgctg ttctacagtt attgatttca
    48481 gaatatctat ataaaaaata tcctaaaaag cctgaaggtg acctatcaaa actccgtgct
    48541 atgattgtcc gtgaggagag tttagctggt tttgcgcgtg attgccagtt taaccagttt
    48601 atcaagttgg gtaaagggga agaaaaatca ggtggtcgca atcgtgacac cattcttggt
    48661 gatgcctttg aagcctttct tggtgccctt cttttggata aggatgtggc caaggtcaag
    48721 gaatttatct atcaagtcat cattcctaag gttgaagcag gcgagtttga gatgattaca
    48781 gactataaaa cccatctcca agagttgctt caggtcaatg gtgatgtggc tattcgttat
    48841 caggtgattt ctgaaacagg gcctgctcat gataaggtct ttgatgtaga agttcttgtt
    48901 gaaggtaaga gcatcggtca aggccaaggt cgttctaaga aattagcaga gcaggaagct
    48961 gccaaaaatg ccgttgagaa ggggctggat tcatgtattt aaaggaaatc gaaattcagg
    49021 ggttcaagtc ttttgctgat aagaccaagg tcgtttttga ccaaggtgtg acggcagttg
    49081 ttggacccaa tggatctgga aagtccaata ttacagaaag tctgcgttgg gctttggggg
    49141 agtctagtgt caagagtctc cgtgggggca agatgccgga tgtcatcttt gctggaaccg
    49201 aaagtcgcaa accgctcaat tatgcttctg tagttgtgac tctggataat catgacggat
    49261 ttatcaagga tgcaggtcaa gaaatcaggg tggaacgcca tatctatcgt agtggagata
    49321 gcgaatacaa gattgacggc aagaaagtcc gtctgcgtga tattcatgac ctcttcttgg
    49381 atactggatt gggacgagat tccttctcta ttatttccca agggaaggtt gaggagattt
    49441 ttaattccaa gcctgaggaa cgacgagcta tttttgaaga agctgctgga gttttaaaat
    49501 acaagactcg cagaaaagaa accgagagta aactgcagca aactcaggat aatctggacc
    49561 gcttagagga cattatctac gagttggata atcaaatcaa gcctcttgaa aagcaagctg
    49621 agaatgcccg taagttttta gacttggaag gacaacgtaa ggctatttat ttagatgttc
    49681 tggttgctca aatcaaggaa aataaggctg aactagagtc gacagaagaa gagttggctc
    49741 aggttcaaga actcttgatg agttattacc aaaagcgtga aaaattagaa gaagaaaatc
    49801 aaactcttaa aaagcaacgc caagatttac aggctgaaat ggccaaagac caaggcagtt
    49861 tgatggattt gaccagtctg attagtgatt tagagagaaa attagcccta tcgaaattag
    49921 aatctgagca agtagccctg aatcaacagg aagcacaagc tcgtttggct gttttggagg
    49981 ataagagaaa ttcactcagc caagaaaaat ctgataaaga aagctcttta gtacttttag
    50041 aggaaaatct agtccaaaat aatcaaaaac tcaatcgttt agaagctgaa ttgctagctt
    50101 tttcagatga tcctgatcag atgattgagc ttttgcgtga acgctttgtg gcgcttttac
    50161 aagaagaagc ggatgtctca aaccaactga cccgcatcga gaatgagttg gaaaatagtc
    50221 gtcagctttc tcaaaaacaa gcagatcaac tagaaaagct gaaagagcaa ttagctacag
    50281 ctaaagagaa ggctagtcag caaaaagacg agcttgaaac tgccaaggtg caggttcaga
    50341 aattattgac tgactatcaa gctattgcca aggagcaaga ggagcaaaaa acttcctatc
    50401 aagctcaaca aagtcaactc tttgaccgtc tggatagtct taaaaacaag caggctagag
    50461 ctcaaagttt ggaaaacatc cttagaaatc acagtaactt ttatgcaggt gtaaagagtg
    50521 ttctccaaga aaaagaccgc cttggtggga ttattggtgc tgttagtgag catttgacct
    50581 ttgatgtgca ttatcaaact gccttagaga ttgcacttgg agccagcagt cagcatatca
    50641 tcgtagaaga tgaagagtcg gcaaccaagg cgattgattt cctcaaacga aatagagctg
    50701 gtcgtgcaac cttccttccg ttgacgacta tcaaggcgcg tacgatttct agtcagaacc
    50761 aagatgttat cgctgcaagt gcgggatttc taggcatggc agatgagttg gtgacattcg
    50821 atacgagact ggaagctatt ttcaagaact tgctagctac gacagcgatt tttgataccg
    50881 ttgagcatgc gcgtgcagca gcgcgcaaag ttcgttatca ggttcgtatg gtgactttgg
    50941 acggtacaga gttgcgcaca ggtggttctt acgcaggtgg agccaatcgt cagaataaca
    51001 gtattttcat caagccagaa ctggagcaat tacaaaaaga aattgctgaa gaagaagcaa
    51061 gtttgcgttc agatgaagtg agtttgaaga acttgcaaga tgagctagct agattgacag
    51121 aaagattaga agccatcaaa tctcagggag agcaggctcg tattcaggag caaggcttgt
    51181 ccctcgccta tcagcagacc agtcagcaag ttgaagagct agaaactctt tggaaactcc
    51241 aagaagagga attaaatcgt ctttctgagg gagaatggca agcggataag gaaaaatgcc
    51301 aagagcgcct tactacaatc actagtgaaa agaataatct ggaagctgag attgaagaga
    51361 ttaagtctaa taaaaacgcc atccaagaac gttatcaaaa cttgcaggaa gagctagctc
    51421 aagctcgtct acttaagaca gaactgcaag ggcaaaaacg ttatgaagtg actgatattg
    51481 aacgcttagg taaggaacta gataatcttg atattgagca agaagaaatt cagcgccttc
    51541 ttcaagaaaa ggttgacaat cttgagaagg ttgatacaga attgctcagt caacaggcgg
    51601 aagaatccaa aactcagaaa acgaacctcc aacaaggttt gattcgcaaa cagtttgagt
    51661 tggatgatat agaaggtcag ctggatgata ttgctagtca tttggatcag gctcgccagc
    51721 agaatgagga gtggattcgc aagcaaacac gtgctgaagc caagaaagaa aaggtcagcg
    51781 agcgcttgcg ccatctacaa agtcaattaa cagaccagta ccagattagc tatactgaag
    51841 cactagaaaa agcgcatgag ttggacaatc tcaatctggc agagcaagag gtgcaggatt
    51901 tagagaaggc tattcgctca ctgggtcctg tcaacttgga tgctattgac cagtacgaag
    51961 aagttcacag ccgtctggat ttcctcaata gccagcgaga tgacattttg tcagcgaaaa
    52021 atctgcttct tgagactatt acagagatga atgatgaggt caaggaacgc tttaaatcaa
    52081 cctttgaagc tatccgtgag tcctttaaag tgaccttcaa gcagatgttt ggcggaggtc
    52141 aagcggacct gattttgact gagggagact tgctgacagc tggtgtggag atttctgttc
    52201 aacctccagg taagaaaatc cagtccctta atctcatgag tggtggtgaa aaagctctat
    52261 cggctcttgc cttgctcttc tccattattc gtgtcaagac tattccattt gttatcttgg
    52321 atgaggtgga agctgcgctg gatgaagcca atgttaaacg ttttggggat tacctcaacc
    52381 gctttgacaa ggacagccag tttatcgtcg taacccaccg taagggaacc atggcagcgg
    52441 ctgattccat ctatggagtg accatgcaag aatcgggtgt ttcaaagatt gtttcagtta
    52501 agttaaaaga tttagaaagt attgaaggat gacaattaaa ttagtagcaa cggatatgga
    52561 cggaaccttc ctagatggga atgggcgctt tgatatggag cgcctcaagt ctcttttgac
    52621 ttcctacaag gaaaaaggga tttactttgc ggtggcttcg gggcgcggat ttctgtctct
    52681 agaaaaatta tttgctgatg ttcgtaatga tattattttc attgcggaaa atggcagttt
    52741 ggtcgaatat caaggtcagg acttgtatga agcgaccatg tctcgtgact tttatctagc
    52801 aacttttgaa aagttacaaa cttcacctta tgtagatatc aataaactgc tcttgacggg
    52861 gaaaaaagga tcttatgtgc tagatacggt tgatgagacc tatttgaaag tgagtcagca
    52921 ctataatgaa aatatccaaa aagtagcgag tctggaagat attacagatg acattttcaa
    52981 atttacaacc aacttcacag aagaaacgct ggaagctggg gaagcttggg ttaatgaaca
    53041 tgtccctggt gttaaggcca tgacaactgg ctttgagtcc attgatattg ttctggacta
    53101 tgtcgataag ggagtggcca ttgttgaatt agctaaaaaa cttggtatca caatggatca
    53161 ggttatggct tttggagaca atctaaatga cttgcatatg atgcaggttg tggggcatcc
    53221 tgtggctcct gaaaatgcac gatctgaaat tttagaatta gcagagacag tgattggtca
    53281 ccataaggac cagtcggtta tagcttatat ggagggctta taatggcaga tataaaattg
    53341 attgcattgg acttggacgg gaccttgctg actactgata aaaggctgac ggatcgcacc
    53401 aaggcaacct tgaaagctgc gcgtgatcgt ggtatcaagg tcgtattgac aactggtcgt
    53461 cccctaaaag ccatggattt ctttctccat gagctaggga ctgacggcca cgaagatgag
    53521 tataccatta cttttaatgg tggtttggtt cagaaaaata caggtgaaat ccttgataag
    53581 acagtctttt catatgatga tgtagcacgc ttgtatgaag aaacagagaa attatcactg
    53641 cctcttgatg ccatctcaga aggaacagtt tatcaaatcc aatcggacca agaaagtctt
    53701 tatgccaaat ttaatccagc cttgaccttt gttccagtgg actttgaaga cttatctagt
    53761 caaatgacct acaacaaatg cgtgaccgcc tttgctcaag aacccttgga tgcagccatt
    53821 cagaagattt ctccagaatt gtttgaccaa tatgaaatct ttaaatcacg tgaaatgttg
    53881 ctagaatggt caccaaagaa tgttcataaa gcaacaggtt tggcaaaact aatcagccat
    53941 cttggaatcg accaaagcca agtgatggct tgtggtgacg aggccaatga cctctctatg
    54001 attgaatggg caggtcttgg tgttgctatg caaaacgctg ttcctgaagt aaaggcagcc
    54061 gcaaatgtag tgacgccgat gaccaacgat gaggaagctg tcgcctgggc tatcgaagaa
    54121 tatgtgctaa aggagaacta agatatggga ttgtttgacc gtctattcgg aaaaaaagaa
    54181 gaacctaaaa tcgaagaagt tgtaaaagaa gctctggaaa atcttgattt gtctgaagat
    54241 gttgatccta ccttcacaga agttgaggaa gttcctcagg aagaagcaga ggttgaaatt
    54301 gttgaacaag ctgtgttcca agaggaggaa atccaagaca cagttgaaga aagtcaggat
    54361 tcagagccag ctgtaggggt ttctcaagaa gaaatagaag aattaccaaa ctcagaagaa
    54421 ttaccagagg aagagaagct tgagcacgaa ggaactatag aagaaaataa ttctgaagtt
    54481 cttgaaccag aaaggcctca aacagaagaa actgttcagg aaaaatatga ccgcagtctc
    54541 aagaagactc gtacgggctt cggtgctcgc ttgaacgcct tctttgctaa cttccgctct
    54601 gttgacgaag aatttttcga ggaactggaa gaactgctga ttatgagtga tgttggtgtc
    54661 caagtcgctt ctaacttaac ggaggaacta cgttacgaag ccaagcttga aaatgccaag
    54721 aaacctgatg cacttcgtcg tgtcatcatt gagaaattgg ttgagcttta tgaaaaggat
    54781 ggtagctacg atgaaagcat ccacttccaa gataacttga cagttatgct ctttgttggt
    54841 gtgaatggtg ttgggaaaac aacttctatt ggaaaactag cccaccgcta caaacgaact
    54901 ggtaagaagg tcatgctggt tgcagcagat accttccgtg cgggtgcagt agctcagcta
    54961 gctgaatggg gccgacgagt agatgttcca gtagtaactg gacctgaaaa agctgatcca
    55021 gccagcgtga tctttgatgg tatggaacgt gccgtggctg aaggtatcga tattctcatg
    55081 attgatactg ctggtcgtct gcaaaataag gataacctta tggctgagtt ggaaaagatt
    55141 ggtcgtatta tcaaacgtgt tgtgccagaa gcaccacatg aaaccttctt ggcacttgat
    55201 gcatcaacag gtcaaaatgc cctagtacag gccaaagaat tttcgaaaat cacaccttta
    55261 acgggaattg ttttgactaa gattgatgga actgctcgag gaggtgtggt tctagccatt
    55321 cgtgaagaac tcaatattcc tgtaaaattg attggttttg gtgaaaaaat cgatgatatt
    55381 ggagagttta actcagaaaa ctttatgaaa ggtctcttgg aaggtttaat ctaatcagaa
    55441 gcaaaaatcc tgcaaggcat aaacttgcag gaaatttttt tattctaagc gaccatcttg
    55501 acgataggcg atatctggtt gccaagtcca tttggcaccg aatttttcaa gtaggtcaaa
    55561 gctggcttga ggtcccatgc ttccagcttt atagtcatga agtggggcac cattttcagc
    55621 ccagagcttt tcaatacgat caatcaactt ccatgacgca ccaacttcat cccagtggct
    55681 aaagttggtt gagttgttat ttaggacatc ataaatcaat ttctcgtatg gttctggaga
    55741 agcaccagtt gcagtcgcgt ctgtacgata atcaagtgag ttaggagcca agttaaattc
    55801 ttctcctact tgcttcccat ttaggctaag agagaagcct tctgttggtt gaatatagat
    55861 ggtcaaaata tttggagcaa gtggttctcc aaagatagaa tccatttgtt taaagacgat
    55921 gttgacatga gttccttttt cagtcagtcg tttacctgta cggaaaaaga aaggaacacc
    55981 acggaatcga tcgctgtcta caaagaaggc accagatgta aaggtttcag ttgttgattc
    56041 tggattcaca tttggttcgc tacgataaga gatgtatttc atgccatcaa tcttaccaga
    56101 gcggtattgc ccacggataa agtgttcttt gagttcttca tcagttggat gatagaggtt
    56161 tttaaagacc ttaatctttt cagcacgaat ctcgtctttt gtgaagcttg ctggtttgtc
    56221 catggcgagg agcgaaagaa gttgtagagt gtggttttgg accatgtcac ggagggcacc
    56281 ggattggtca tagtagccac cacgttcttc tacacccaag cgctccgcaa aggtaatttg
    56341 aacattgtcg ataaaatcct tgttccaaac gttttcaaaa atcaagtttg caaagcgaac
    56401 tgcaaagatg ctttggatca tttccttacc aagataatgg tcgatacgga aaatttgttc
    56461 ttcgtcaaat gttgctagga gttcgtcatt caacttgctt gcagttgcgt aatctgtacc
    56521 aaatggtttt tcaacgatca agcgctcaaa acctttgcca tcgacaatgt tttcagattt
    56581 gaggtgtttg gcaatggttc caaagaactg aggtgccata gacaagaaga agagcttatt
    56641 gtgttcagct tggtattttt cattaagctc agcttgtaat tgacgcaaag caatataatg
    56701 ttccgaatca ttgacatcat ggctttgata gtagaagtgg ctagcaaatt cttgggcttg
    56761 ctcggtacta tctgccaaat caaggatgga ctcgacaact acagattcaa aatattcctt
    56821 actccaaggt ctacgggcag ttccaataac ggcaaagtgc ttggaaagat tgccggattt
    56881 atatagtcta aaaagggaag ggtagagctt gcgtttagcc aggtctccac tcgcaccgaa
    56941 aattgtaaca ataaccttag atgacatcta gctacctaat ttctattttt attcctagtc
    57001 ttgctaggta tgaggaaacc tcatttcata aacttaattc taacataatt ttccgaaaaa
    57061 tcaaaaattc caatacgagg tagaaaaact gcaaggaaat ccttacagtt tgagtttaga
    57121 cgtttaagac cttatctaag aactctttca gacgagggtg ttgtgggtta tcaaagattt
    57181 ggtcaggtgt tccgtcttca aggaactcgc catctgcagt aaagataacg cggttggcaa
    57241 cctgacgagc aaatcccatc tcatgggtta cgataatcat ggtcatgcct tgctcagcca
    57301 attccttcat aacgttaagt acgtctccaa ccatctcagg gtcaagggca gaagttggtt
    57361 catcgaagag catgatgtct ggattcattg ctaggccacg agcgatggcc acacgttgtt
    57421 tttgaccacc tgataggcta tctggattgg cattagcttt atctgctagt ccaacctttt
    57481 caagcaactc cattcccaat tcctcagctt cttccttagt catcaacttg tgctcaatag
    57541 gagcaaaggt gatgttgtcc aatacagaca tatgagggaa gaggttgaag tgttggaata
    57601 ccatgccgat attttcacgg acgtggtcaa cattggttgt tttttcagtt aaatcatagc
    57661 cgttcacagt gatgtgaccg ctagtgactt cttctaaaag attgaggcta cggaggaaag
    57721 ttgacttacc agaacctgaa ggaccgatga tacaaacaac atctccttca tagaacttag
    57781 tcgtaattcc ttttaggact tcattttttc catagtgctt gtgtaaatca tttacatcaa
    57841 tttttaattt tgccattaac gaatcctctt ttctaagcgt ttcgctagtc tagtcaaaag
    57901 tgtgataatt acaagataga agatagcaag gattgcatac atcttgaaac tttggtagtt
    57961 acgagcaatg ataatcttac cagtttggaa gagttcaacc aaaccgatag cagatacgat
    58021 agttgtatct ttaagagcga taacgaattg gttgacaaag tttggcaaca tcaatttagt
    58081 tgcttgtggc aagataatct tacgcatggt ttttccataa gagataccca agcttcggct
    58141 ggcttccatt tggccaactg gaacggcctg aataccacca cgaacgattt cagcgatata
    58201 agcagccgca ttgagtgaga gggcaattgt tccagctaca aagtcgttaa ttgggctttg
    58261 ttggcctgtg atagactcga tgaagtttgg aattccccag aagatgaagg ctgcaagaat
    58321 catcaatgga ataccacgaa taacgtcaac gaaaatctca gagatgacgc gaagagattt
    58381 gtatgggcta acgctaaaca taccgaagat aattccgatg acaatggcaa tagcaaatga
    58441 gataagagct agagcaagag tgataccaag accgctaagg agttgtttgt agttgttttg
    58501 aagcaagccc cagagcgttg tttcgtcaac agtacttgtt gaagcagttg aagattcgct
    58561 agctaggtat ttgtcaagaa tcttttggaa ttcaccgttt gctttaaggt ttgcaagtcc
    58621 gttgttgaac atttcaatca gttctggatt tgctcctttt ttaacggcaa aggctgtttc
    58681 accgattgga gttccagaga ttggagtttt caatttttga ccttggctga tagaatattt
    58741 gagaacaggt tcatcatcca taacggcatc aatggcacca gtgtttaaac tgtcatacat
    58801 tgaagaacca tcagcaaagg ttttgatttt gtaaccgtat ttgctttgat tttctgttag
    58861 gaaggtttga gaagcagttc cgtttttaac accgactgtc tttcctttta gatcttcata
    58921 agaagcaata ttgcttgatt ctttgacacc aagaatggta ttagcagtgt agtatgattc
    58981 tgagaagtca aaagttgcct tacgagcatc tgtgacagac ataccagcaa tgataccatc
    59041 ggcttgacca gcttggacag cactgatagc agcatcaaaa ccagggttgg tgatttcaat
    59101 ttcaaaacct tggtctttag cgattgcctt aatcaattcc atatcaatac cagtgtattg
    59161 gttgcttgaa ttttggaaaa caaaaggtgc aaaagaagaa tcgctggcaa tgatatattt
    59221 agccttaaca ggaatagctt ttaatcctgc gagagtggtt gtagttggca ctgctgaaga
    59281 tgatgaagca gtccatttct tgataatttt atcaagacta ccatcttttt tcatttcagc
    59341 caaggcttgg ttaaattcag taaccaggtg ttcgtattta cttccttttt tcacaccgaa
    59401 agcaaaactt cctacagctt caccatccat ttcaatatgg aggtcttgac cttggttaat
    59461 ggcatattcg ataacaggtt tgtcatccat catggcatcg atggcaccag cactcaagct
    59521 gttgttcatt aaatccccag tgtcaaatgt tttaatagta aagccgtatt tatctttgat
    59581 tgtttcaagg aaacgttgag cggcagttcc gtttttaaca ccaacggttt tgccagttaa
    59641 ttggtcgtac ttgctaattt tgtgtgactt tgtagtagca atgacaactt ttgtatcata
    59701 gtaagtatca gacatggtga agactttttc acgttcttta gtctttgtca tccctgccat
    59761 gatagcgtcg gcttgcccag cttgaaccgc attgactgct gcgtcaaatc caggatagga
    59821 catctgaatg ttccagcctt taatctcagc gactttgtta ataatgtcaa catcaattcc
    59881 tttataagtt tgatctgaat ctttaaactc aaaaggtgca taggcggtat cagaaacaat
    59941 cttaatcgtt tctgctttgg caatacctaa tgagaaaatt gggaataaaa ttagcaaaaa
    60001 tgctagaaat tttttcttca tttttagtct ccttttccga atattctctc attatatcag
    60061 aaaaagtaaa aaaaggcaaa tttttatatt ttcgtgtcag aaaatataac attgattttt
    60121 tcctttcctt gaattgctat taaaaagtgc tataataata gtatatatag aagaaaagag
    60181 gacggggata tgaagaacaa aagaatattt aaagacttcc aagcttcaaa aatgagttta
    60241 aacatttaca caagcccctt gttagtcttt gtttttgtct tcataggaga gtttgtggct
    60301 tttactttgt atggtattgg cttgttagct ctcatcggac ttgctagaaa ttttggagag
    60361 gctggtcaaa atcttgcaag ctacttgcag accttgcatc agagcttgac ggataaaaca
    60421 agtgactttc gtttaatttt aggattactg gcctttggtt ttattcttaa cactgtgttc
    60481 agatggacaa gaaaagttga gaaaagacct attcgaacct tgggatttta tagagagaat
    60541 ttcctcagca atcttctgaa aggatttagt ctaggtctgg cactttttct tctgaccttg
    60601 ttaggtttgg tggtcttagg tcaatatcgt ttggaatcca ttcacttgaa tccttattct
    60661 cttgcctttg tcgtctttac tatcccattt tggattttac aaggaacggc agaagaattg
    60721 gttactcgtg cttggctgat tccacaattg gctaagagaa ccaatcttaa agtcgctatt
    60781 atcatatcta gtagtctctt taccttactt catttaggaa atccaggcat aactttctta
    60841 tctgcaattg atctcttttt attcggagtt gccatgtccc tatatcttct taaaacagat
    60901 actatatggg gtataggtgg tattcatgga gcttggaatt tcgcacaggg aaacctcttt
    60961 ggagtattag ttagtggtca gtcttcagga acatcaatca tgagatttac tccacaaggc
    61021 aatcaagact ggctatcagg aggatctttt ggtattgagg gttccatcgt gtccagtatt
    61081 attttgtttc tgctgattct ttatctcgct catcaattaa agaaagaaaa tgaaaggatg
    61141 tgacttcggt ccgtcctttt cttcgtgaaa atgctacaag tatgctaaaa taggaatagc
    61201 acatggagag aggattctta tgatcaatcg cattacagat aatcaattta aactagtatc
    61261 aaaatatcaa ccttcaggag accaacctca agctattgag cagttggttg ataatatcga
    61321 ggggggagaa aaagctcaga ttctgatggg ggcgaccgga acagggaaga cctataccat
    61381 gagtcaggtc atttccaaag tcaataaacc aactctggtt attgcccaca ataaaactct
    61441 agcaggccag ctatatggag agtttaagga atttttccct gaaaatgcag ttgagtattt
    61501 cgtatcctac tatgattatt accagccaga ggcctatgta ccttctagtg atacctatat
    61561 tgagaaggat agttctgtca atgatgagat tgacaagctc cgccactcag cgacttcggc
    61621 tcttttggag cgtaatgatg ttattgtcgt ggcctcagtc tcttgtatct atggtttggg
    61681 ttcgcccaag gaatacgctg atagtgtcgt tagtctccgt ccaggtcttg aaatttctcg
    61741 tgataaactc ttgaatgact tggttgatat ccagtttgaa cgtaatgata ttgatttcca
    61801 acggggaaga tttcgtgttc gtggggatgt ggtggagatt ttcccagcat ctcgtgatga
    61861 acacgctttt cgagtagaat tttttggaga cgaaattgac cgtattcgtg aggttgaggc
    61921 cctgactggt caggtattgg gagaagtgga tcatttagcg attttcccag ctactcactt
    61981 tgtgaccaat gacgaccaca tggaagtggc cattgctaaa attcagactg agttggaaga
    62041 gcagttagct gtctttgaga atgagggcaa actgttagaa tcccagcgtt tgaaacagcg
    62101 gacagagtat gatatcgaaa tgttgcgtga gatgggctat accaacgggg ttgagaacta
    62161 ttcacgtcac atggatggac ggagcgaagg tgagcctcct tatacgctct tagatttctt
    62221 cccagatgat ttcttaatca tgattgacga gagtcacatg actatgggac aaataaaagg
    62281 catgtacaat ggagaccgtt cgcgtaaaga aatgctagta aattatggtt tccgtttgcc
    62341 gtctgctctg gacaatcgtc ctctccgtcg tgaagaattt gaaagccatg tgcatcagat
    62401 tgtttacgtt tcagcgacac caggtgatta tgaaggtgaa cagactgaga cagtgattga
    62461 gcaaatcatt cgtccaacag gactattgga tccagaggta gaagtccgtc cgacaatggg
    62521 acagattgat gacctcctag gtgaaatcaa tgcccgtgtt gaaaagaacg aacggacctt
    62581 tattacaacc ttgaccaaga aaatggcaga agatttgacc gactacttta aggaaatggg
    62641 catcaaggtc aagtacatgc actcggatat taagaccttg gaacggacgg agattatccg
    62701 tgacctgcgc ttgggtgtct ttgatgtctt ggtcggaatt aacctgctcc gtgaagggat
    62761 tgacgttcct gaagtgagct tggttgccat tctcgatgct gacaaggaag gtttcctacg
    62821 taacgaacgt ggactcatcc agaccattgg ccgcgctgcc cgtaatagcg aaggtcatgt
    62881 catcatgtat gcggacacgg ttacccagtc tatgcaacgt gccatcgatg aaactgcccg
    62941 tcgtcgcaaa atccagatgg cttataatga agagcatggt atcgtaccac aaaccattaa
    63001 gaaagaaatc cgtgacttga ttgccgtaac caagactgtt gccaaagaag aagacaagga
    63061 agttgatatc aatagtctta acaaacaaga gcgcaaagaa ctggtcaaga aactagagaa
    63121 acaaatgcaa gaagccgtcg aagtgcttga ctttgaacta gcagcacaga ttcgtgatat
    63181 gatgttggaa gtcaaggcct tggattaggg gaatagtatg atttatttaa gaaagttaaa
    63241 gaaagaagat ttgatgtctt tatgggaaat ggcttattca cagcttaatc cagtctggaa
    63301 acagtatgat gctccctatt atgatgatta tcagtatttt tcaaatttta aagaattcga
    63361 actacaaaaa tcagaatcca ttttaagcaa ctcaaatcgc cttggtattt ttgttgatga
    63421 taaactagtt gggactgttt cgcgttattg ggtatgtaaa caaacaagat ggatggaatt
    63481 gggaattggt atttatgata aaaaattctg gaacactggt attgggaaaa ttgctatgtt
    63541 gcagtggata gataggacgt ttcaggatta cttggagttg gagcatctgg gtttgacaac
    63601 ttggtcagga aatattggta tgatgaaact tgctgaaaaa ttaagaatga aaaaagaagc
    63661 tcatattcca aaagttcgtt attatcaagg taaatatttt gatagtatta aatatggtat
    63721 tttgagagaa gactgggaga aaataaatga cgattattat caaattaatg aaaactcctg
    63781 aagagataga aggtaaatcc cttgttcact ggcaaacgtg gagagaagct tatgatgacc
    63841 ttttgcctgc ggaatttcag gagacaatga cattagaaag gtgtcgattc tttagtaaaa
    63901 agtatccaga aaatacatgg attgcgatgg atggtgtgaa ggtagttggt tttatcagtt
    63961 atggcaattt tcgtgatgag actattcaag ctggtgaaat tattgcttta tatgttttaa
    64021 aagactatta tggaaaagga atcgcacaaa agttagtgaa agtagctttg actgctcttg
    64081 atcatttttc tgaaattttc ttatgggtat tgaaagataa taagcgagcc attgctttct
    64141 atcaaaaaat gggttttact tttgatggac aagaaaaaat acttgaactt ggaaagccta
    64201 taaaggaaaa acggatggta ttctattcta aataatttta aaaagtagaa gctaatggca
    64261 ctggtacaag tctgaaaatt taataaatta gaaagtgagt aaatttatgt cacgttccca
    64321 attaacgatt ttaacaaaca tttgtcttat tgaagacctc gaaacgcagc gcgtggtgat
    64381 gcagtatcgc tctcctgaaa ccaatcgctg gtctggttat gcctttccag gaggacatgt
    64441 agaaaatggc gagtctttcg cagagtctgt cattcgtgaa atctatgaag agacaggatt
    64501 gactatccaa aatcctcaac ttgtcggtat taaaaattgg ccactagata caggtgggcg
    64561 ctatattgtc atttgttata aggcgactga gttctctggt acccttcgct cttcagatga
    64621 aggagaagtt tcttgggtgc aaaaagacca gattccaaac ttggatctgg cctatgatat
    64681 gttacccttg atggaaatga tggaagctcc ggacaaatct gaatttttct accctcgccg
    64741 tacagaagac gattgggaaa agaaaatttt ctaatccttt actaaataac ctagctgatc
    64801 caaggcctcc tcgatatagt ggaggtcttg ttgtgtttcg gcttcgacta ggtggtaatg
    64861 gacgccatct gtcaattcag atagaggtct aaagtcagaa tgctcgactt gttctagaaa
    64921 atgttgcaca tctctgcgac aagacagttt aagcaaggtt tcaatttctc cataaacggg
    64981 atggtcaatc aaggtattct ggacatgccc gccattatcg acaatagcaa ggagttcctg
    65041 accgatttct tcaacttcat gtttcacttt gaaaagtttg tgaacataag gattggtatc
    65101 aatttgctta tagatgtagc cacgattggt ggataggata ggagcgccat cggctctcaa
    65161 aattgcaatg tcctgcacaa tgacctgacg tgtgacatga aaatgttccg ccaaactttg
    65221 gccattaagg gctttaggag cttctttcaa gagttggagc agggcttgtt tgcgatcttt
    65281 tgtcatagct tttcctttta acggcgtttt cgaagcactt tatagacagc tagtgctaat
    65341 gtatagtcta ccatactatg gataattgtg ccaaatccaa ctagtacaaa tagaacatag
    65401 aacatgtttt ctacattggt acccgaagtt gcgtaaaaaa ggacacaggc taatacttca
    65461 gcaagggcat gaacaacagc caaaacaaag ttgaaaatcc aggaagattt tggtttatct
    65521 agggtatcgg ggaatttttg taggtaaaga gctcctaaag caccaaaaga tatatgggaa
    65581 aaagcccgaa aaacgataac catgggatag ccagccatca aaaatccaaa actagaggct
    65641 aggatgacaa aaactgccat caagggcgac aagaacatgg ctataaaaat agcgatgtgg
    65701 ctccccaaag tataggaagc aggtggaatg acaatcttga aaggcataac aattggaatc
    65761 aaaatcgcaa tagccgttaa aagggctgtc attgtcataa attgtgtctt tttccgtgta
    65821 ttcacaagaa tctccttttt aactgcatat acactagtat ggtacaataa accagacaat
    65881 aaagcaagaa tttacttggg tttatagatc attttttagt taaaagttat agtagattga
    65941 aactagaata gtccacctct acttctaaaa cattgttaga aatcgatttg gctgtcctga
    66001 tcgatttgtc ctgttcttat ttcgttttac tatagtaaag atttcattaa aaagaaactg
    66061 tatagagcaa aatctccacc ttcaggtttg aaagcggaga ttgtttttat tttttcaagg
    66121 tttgtagtcg tggaacaatg gctagggtta gaattgcaga aatgaccaat tcagcaattg
    66181 aatttgttga gataacggtt gccagaagaa gttggatatt tccattataa acatttccaa
    66241 ataggaagaa gattcctcca aggacaaaga tagtatttgt caaggaacca agggccccag
    66301 ctaaaatcag accagtcttg tttttcatca gtttatagac taagtaagga gttaaaccaa
    66361 tcaaaatacg tgggacgatg gcaatgatag ctgagtagat gtttccgttt ggtacgaagg
    66421 gagagaagag gtagcttgtc ggtagaatcg taatcgtgtt aaccgtcaag ctaagtaatc
    66481 ccatcaaaaa tccaagtgta accccaactc gtggaccata aataatgctg gcaataatga
    66541 caggaatatg aacaatggtc ggtttgattg gaaatggaaa aaggttaaag ataagtgagc
    66601 tcagaaagtg tatcacgagc atggtagcaa aaaagatagc aatgggtgca atattagagc
    66661 gttttttcat cgatagtttc ctttattctt tctaaaataa ttgtgaggtc agctaaagct
    66721 cctcgtccgt ggtctccaca agctagtagg gattccttag gagcaatcag ctgatagccg
    66781 taggtttcta atgttttcag attattctga gttactggat ggtcatacat ttttgtattc
    66841 atagcaggag ttattagttt gggaatatga cttggtaggg ctagagctgt actggttacc
    66901 atgttgtccg caaatccgtg agctagtttt gcaatagtgt tagcagttgc aggtaccacg
    66961 ataaataaat ctgctttttt tccaagttcg atatgattga cctgatcagg atagggttcc
    67021 ttcatgacat ccaagtggac aggattctgt gagagtacct gtagtgtcaa aggttggata
    67081 aactctgtag cagcctgagt cattaagaca gtgacttgat ggccttgttt ttttagagaa
    67141 ctgactaaat ctgccgactt ataagaggcg attgaacccg ttacagccaa gagaatgttt
    67201 gccatagttt tcctttctaa gaatgatagg cttgaatttt ttcaaggagg agttctgcaa
    67261 tttcttcttt agtctggact gtttgaagct gatttttctc aacaaatata gctcggtgct
    67321 gatctgttga aatttgagtc aggtcattcg cgatgattaa atctgcttga ttcttgataa
    67381 gactttttcg tgcaatgtca accagatgat cttcggtaac atcaaccagc agtttgaaac
    67441 caatcagatg aatagtagga ttccattcct tgactaggga tatgattttg ggtgtctttt
    67501 taaggaacaa aacctgaacc tcatcagttg aagaaatctt ggcctgatga ttttgcttgc
    67561 ttaaaaattc ttttagattg gagctagcct gaacttcctc aagccctgtc atataaacag
    67621 gagtgtagtc agaaacagcc attgagtgga tcaagacctg ataatcctga acacgttctt
    67681 gcatttctat tagaaggtcc ttggtattgg taatttctcg aatacttagg ttaggatgag
    67741 gctctggctt cagagctcgt tttgtcgtaa ttaaacaaac ttcataccct gcagaaagca
    67801 aagtctctgt gataattttc cccaagtgac ctgtagaatg gttagtgata gagcggacgc
    67861 tatcgatagc ttcactggta ccgcccgatg taactaaaat tttcatagca ctattgtaca
    67921 caaaaataag cggtaagtaa aatgaaagtg ataaattttt ggtaaaaacg aagatttatt
    67981 atagtttcaa actataaagc catataaaat ttaagaaagg actctaaaag tcttaaaaac
    68041 agagatattt acgaacgttt agagagtttt aggatgttaa aaatcttgtt ttgtgatata
    68101 atgaattatc atataagagg ttagaggaat tttgaatgaa aacagatatt gaaatcgcac
    68161 agagtattga gttgaagcca attgttgatg ttgtagagaa acttggtatt tcttatgacg
    68221 atttggagtt gtacggaaag tacaaggcta aactcagctt tgataaaatt cgtgcagttg
    68281 agagcaatct agtcggtaaa ttgatcttgg ttactgccat caacccaaca cctgcaggtg
    68341 aaggaaagtc gacgcttacc attggtcttg cggatgcctt gaacaagatt ggcaagaaaa
    68401 ccatgattgc tatccgcgaa ccgtctcttg gtccagtcat ggggatcaag ggtggtgctg
    68461 ctggtggtgg gtatgcacaa gttctgccaa tggaagacat caacctccac tttactggag
    68521 atatgcatgc tattacaact gccaacaatg ccctttctgc cttgattgac aaccacttgc
    68581 accaagggaa tgagctggaa attgatcaac gtcgtatcct ctggaaacgc gttgtggact
    68641 tgaacgaccg tgcgctccgc catgtgactg ttggtcttgg tggtcctcta aacggtattc
    68701 cacgtgagga tggttttgat attacagttg cttcagaaat catggcaatt ctttgcttgg
    68761 caacggacat cgaggacttg aaacgtcgtt tggcgaatat cgttattggt tatcgctatg
    68821 accgtacgcc tgtttctgta ggtgatttgc aggttgaggg tgccttggct ttgattttga
    68881 aggatgctat taagccaaac ttggttcaga caatttacgg tacacctgcc tttgtacacg
    68941 gtggtccatt tgccaatatc gctcatggct gtaactctgt tttggcgacg acaacagccc
    69001 ttcacttggc tgattacact gttactgaag ctggttttgg tgcggacctt ggtgctgaga
    69061 aattccttga tatcaagaca ccaaacttgc caacatctcc agatgcagtt gtcattgtcg
    69121 caacccttcg tgcccttaag atgaatggtg gtgtggctaa agacgctctg actgaagaaa
    69181 atgtagaggc agttcgtgca ggttttgcta acttgaaacg tcacgttgaa aatatccgta
    69241 agttcggtat tccagcagtt gtagctatta acgaatttgt atctgataca gaagctgaaa
    69301 ttgcagcctt aaaagaactc tgtgcctcaa tcgatgtacc agttgaattg gctagtgtct
    69361 gggctgatgg agcagaaggt ggagtagcac ttgccgaaac agttgttaag acaattgctg
    69421 aaaatccagc taactataaa cgtttgtacg ataatgacct ttctgtccaa gaaaagattg
    69481 aaaaaattgt cactgaaatc tatcgtggta gcaaagtgaa ctttgagaag aaagctcaaa
    69541 cacaaattgc tcaaatcgtt caaaacggtt gggacaaatt gccaatttgt atggctaaaa
    69601 ctcaatacag tttctcagac aatccaaatg cgcttggagc accagaaaac tttgaaatta
    69661 ccattcgtga attggtacca aaattaggtg caggcttcat cgttgcctta actggtgatg
    69721 ttatgaccat gccaggtctt ccaaaacgtc cagcagctct caacatggat gttgaaagcg
    69781 atggaactgt actaggcttg ttctagtgga ttgaaattga ctttaagtga gtttggaaat
    69841 aatatccaag ctcatttttt ctcagactgc aagcagttca tcaataagat ttatactctt
    69901 cgaaaatctt ttcaaactac gtcagcttca ccttgccgta ggtatatgat actgactctg
    69961 tcagttctat ccacaacctc aaaacagtgt tttgagcaac ctgcggctag cttcctagtt
    70021 tgctctttga ttttcattga gtataagtag atagaaaagt tatatactat ctattgaaaa
    70081 tattataaat cagatacaaa gacaggtgaa accttctgtg ttatactaga gatatgttag
    70141 atttgaaaga atacggtatc gtcatgtggc cggaggagaa agtcatttct ttccgtgaga
    70201 aacttctcgc ttggtatgat gaaaacaaaa gagatttgcc ttggaggaga agtaaaaatc
    70261 cttatcacat ctgggtatct gaaatcatgc ttcagcagac cagggtggat acagttatcc
    70321 cttactacga aagatttttg gactggtttc caactgtcga aagtctggca actgcgcctg
    70381 aggagagttt actgaaagct tgggagggct tgggctatta ttctcgagtt cgcaatatgc
    70441 aggctgcagc ccagcagatt atgactgact ttggtggcca atttccaaat acctatgaag
    70501 gaatttccag cttgaaaggg attggacctt acacagcagg agccatttcc agtattgctt
    70561 ttaacttgcc tgagccagct gtagatggta atgtcatgcg ggtcttggcg cgtctgtttg
    70621 aagtcaacca cgatattggg attccaagta atcgaaaaat ttttcaggca atgatggaga
    70681 tcttgattaa tccagatcgt ccgggtgatt ttaatcaagc cttgatggac ttagggtctg
    70741 atattgagtc tcctgtaaat cccagacctg aagaaagccc agtcaaggac tttagtgcgg
    70801 catatcagaa tggaaccatg gaccgttatc caattaaatc tcctaagaaa aagccggttc
    70861 ctatttatct taaagcctta gttgtgaaaa attctcaagg acaattttta cttgaaaaaa
    70921 atgaaagcga aaagctcttg gcaggttttt ggcatttccc ctttatagaa gttgataact
    70981 tttcgcaaga agagcagttt gacctctttc atcaggttgc ggaagaaagt gtgaactctg
    71041 gccccagtcc agaagagagt ttccagcagg actatgacct agatgttgat tggcttgatg
    71101 tttgttttga tacagtccag catgttttta gtcatcgaaa atggcatgta cagattgtag
    71161 caggtcaggt gagtgacttc catgattttt cagataggga agttcgttgg ctttcaccag
    71221 aagaattcaa gaattaccca cttgccaaac cccaacaaaa aatctggcag gcttatgcac
    71281 aagccaactt agacagtagc caagactagc tattgtgtct tctgactatt ttttggtata
    71341 atagtagaga aaaaggtgaa catatgaaaa aaatactaat tgtagatgat gagaaaccaa
    71401 tctcggatat tatcaagttt aatatgacca aggaaggtta cgaagttgta actgctttta
    71461 atggtcgtga agcgctagag caatttgaag cagagcaacc agatattatt attctggatt
    71521 tgatgcttcc agaaattgat ggtttagaag ttgctaagac cattcgtaag acaagcagtg
    71581 tgcccattct tatgctttca gccaaagata gtgaatttga taaggttatc ggtttggaac
    71641 ttggggcaga tgactatgta acgaaaccct tctccaatcg tgagttgcag gcacgtgtta
    71701 aagctcttct gcgtcgttct caacctatgc cagtagatgg gcaggaagca gatagtaaac
    71761 ctcaacctat ccaaattggg gatttagaaa ttgttccaga cgcctacgtg gctaaaaaat
    71821 atggcgaaga actagactta acccatcgtg aatttgagct tttgtatcat ttagcatcgc
    71881 atacaggtca agtcatcacg cgcgaacact tgcttgagac tgtctggggt tatgactatt
    71941 ttggtgatgt ccgtacagtt gatgtgactg tacgacgtct gcgtgagaag attgaagata
    72001 cgcccagccg accagagtat atcttgacgc gccgtggtgt agggtattac atgagaaata
    72061 atgcttgatt tactgaaaca aaccattttt accagagatt ttatctttat cctgattttg
    72121 ttaggtttca tccttgttgt gaccctctta ttactggaaa atagacgtga taatattcag
    72181 ttgaagcaaa tcaatcaaaa ggttaaagat ttgattgcag gagattattc caaggttctt
    72241 gatatgcaag gtgggtctga aatcactaat attaccaata atttgaatga cttgtcggag
    72301 gttattcgtc tcactcagga aaatctagaa caagagagta agaggctaaa tagtattctg
    72361 ttttatatga cagatggggt tcttgcgacc aaccgtcggg gtcagattat catgattaac
    72421 gatacagcca agaagcaact ggggttggtt aaggaagatg ttctgaatag aagcattttg
    72481 gaattgctca agatagaaga aaactatgaa ttgcgtgatt tgattaccca aagtccagaa
    72541 ttgttgctag attcccaaga tatcaatggc gaatatttga accttcgagt tcgctttgcc
    72601 ttgatacgtc gagagtctgg ctttatttca ggtttggtgg ctgttttgca tgatacgacg
    72661 gagcaggaga aggaagaacg cgaacgaaga ctctttgttt ccaatgttag ccatgagtta
    72721 cggactcctc tgactagcgt aaaatcctat cttgaagcct tggatgaggg ggctttgtgt
    72781 gaaactgtag caccagactt tatcaaggtt tctcttgatg aaaccaaccg tatgatgcgc
    72841 atggtgacgg atctcctcca tctttcacgt attgataatg ctaccagtca tctagatgtg
    72901 gaactgatta acttcactgc ttttattacc tttatcctca atcgttttga caagatgaaa
    72961 ggacaggaaa aggagaaaaa atatgagttg gtgagagatt atcccatcaa ttctatctgg
    73021 atggaaattg atacagataa gatgacgcag gttgtcgaca atattttaaa taatgctatt
    73081 aagtattcgc cagatggggg taaaatcact gtcagaatga agacaactga agaccagatg
    73141 attttatcca tttctgacca cggtttgggg attcctaagc aggatttacc acgtatcttt
    73201 gaccgtttct atcgtgtgga tcgtgctaga agtcgtgcac aaggtggtac aggtctagga
    73261 ctgtctatcg ctaaagaaat tatcaaacaa cataagggct ttatttgggc caagagtgaa
    73321 tacggcaagg gttcaacctt taccattgtg ctcccttatg ataaggatgc agtgaaagaa
    73381 gaagtatggg aggatgaagt agaagactag aatgagtgaa ataggcttta aatacagtat
    73441 tttagcgtcg ggttccagtg gaaattcttt ttatctggaa acctcaaaaa agaagctttt
    73501 agtagatgca ggcttgtctg gcaagaaaat taccagtctg ctagctgaaa ttaaccgtaa
    73561 gccagaagac ctggatgcca tcttgattac ccatgagcat tcagatcata tccatggagt
    73621 aggcgttttg gctcgcaagt atggtatgga tctttatgcc aatgaaaaga cctggcaagc
    73681 tatggaaaat agtaaatatc ttggcaaggt ggattcttcg caaaagcata tttttgaaat
    73741 gggtaaaacc aaaacctttg gagatatcga catcgagagt tttggtgtaa gccatgatgc
    73801 agtcgcaccg cagttctatc gctttatgaa ggatgataag agttttgtcc ttttgacaga
    73861 tacaggttat gtcagtgacc gtatggcggg cattgtcgaa aatgcggatg gctatcttat
    73921 cgaggccaac catgatgtag agattttgcg atcaggttct tacgcttggc gactcaaaca
    73981 acgaatccta tctgaccttg gtcacctttc taacgaggac ggtgctgaag ctatgattcg
    74041 gacgctagga aatcgtacta agaagattta ccttgggcat ttatctaagg aaaataatat
    74101 caaggaactg gctcatatga ccatggtcaa tcagctggct caagctgatc tgggagtcgg
    74161 agtagacttt aaggtttatg atacctcacc agataccgca acaccattga cagagatata
    74221 aaaagaacgc tgagaaggtg ttctttttat attgactgaa cacctaaaaa gtaatacaat
    74281 ggtgttacca ttaaaaaagg gagcacaaaa gatgactact attacattaa aagtttctga
    74341 agctgataaa acatttatga aagcaatggc taagtttgaa ggagtttccc tttcggaact
    74401 tattcgcacc aaaactcttg aagccctaga agatgaatac gatgctcgtg tggcagattt
    74461 agcctatcaa gagtatttag aagacttgga aaaaggagtt gaacccatta cttgggaaga
    74521 aatgatgcat gatttaggct tgaaggatga ataatttgta taaattagtt ccaacaagac
    74581 gttttatcaa gcaattgaaa aaattggacc gttatacgca gaagctaatt acaaactatt
    74641 tacaaaccaa tgttttggaa ggcccaagac gacacggaaa ggctttggtt ggtaatcgcg
    74701 ttggtcaatg gcgctataga attggtaatt atcgagttat cgtacaaatt gtagatgatg
    74761 aattagtcgt tgctactcta gaagttggtc atcggagaga tatttattga attaaagctg
    74821 agtaataaca atatagaaag taaggagagt aaaaatttga agaaaaaatg cttttttgca
    74881 gattattatg atacaacaat tattttactt gctttaatct ctgttattct ggtattactt
    74941 ggatttgctg agatgattga tttggacaat ccgccttata gtattattga tttagtaatc
    75001 tggggtgttt ttgtaattga ttatagttgg cgctttttta ttactaaaag aaaatggcgc
    75061 tttattcttg aaaatatttt tgatttattg gctattctcc ctttaaatgc tatttttaca
    75121 gtgtttcgat tagggcgtat ctttcgttta gctaaactaa caaaattact gaaactgact
    75181 cgtttactta gaataattgg acttacaggt aaattagaaa gaaaaattag tagattctta
    75241 cggacaaatg gcttgattta tatcttgtat gttaatatct ttatcgtgct agtaggaagt
    75301 tcaattttat ctgtagttga agaaaaatcc ttctcagata gtctttggtg ggctcttgta
    75361 acggtaacga ctgttggata tggggatatt gttcctgctt ccatttttgg gaaatggcta
    75421 gcagttttac tgatgcttgt cggtattgga acaataggga tgttaacaag tgctttgacg
    75481 aacttttttg taaaggataa tccagatgaa cagataaaac ttgataaact ccaagatgaa
    75541 ttatctagtc agagaatatt actagagaaa caatctaaaa agatagaaga actacataaa
    75601 atgatacaag atttgattga aaaaacataa taaaaataaa gatgagaaaa agtttgaact
    75661 gaggagaaat caagtaagtt ttgacacaat agaacgcata ttatcaggta taaaaacttg
    75721 atactatgcg ttttattgtg ggaagatgta taatggattg aaataagata tgaacaaatc
    75781 gattaggaat ttaaagcatt ttataacaac gttttagagt aacggggtac tatttcatat
    75841 aatacaggaa aaaacaactc cctgatgatt caaggagttg tctatagtta aattagtttt
    75901 tagaagcttc ttggaattct ggatttttcc atgcttcgtc aataatagct tgcaattctt
    75961 tagcagatgc ttgcattttt tgagtttctg catcgttcaa tggaatgttt actggacgaa
    76021 cgataccatg tgcaccaaca acagctggtt gaccgataaa gacattctca actccgtatt
    76081 gaccttcttg gaatactgaa agtggaagta ctgcgttttc atcgtcaagg attgctttag
    76141 tgatacgagc aagggctact gcgataccgt agtatgttgc accttttttg ttgatgattg
    76201 tgtaggctgc atcacgaaca ccttcgaaca attcaatcaa ttcagcttct tgaacatttt
    76261 gagtgtcttt aaggaattct tcaaggttta caccagcgat gttagcgtgt gaccaaacag
    76321 cgaactcaga gtcaccgtgt tcacccatga tgtaggcgtg cactgaacga gcatccacat
    76381 ccaatttttc agcaagtgct tgacggaaac gagctgagtc aagtgaagta cctgaaccga
    76441 taacgcgttc tttagggaaa ccagagaatt tccaagttga gtaagtcaaa acgtcaactg
    76501 ggttagcagc aacaaggaag atacctttga aaccagattc aacaacttga gttacgattg
    76561 atttgttgat agcaaggttt ttacctacaa ggtcaagacg agtttcacct ggtttttgag
    76621 gtgcacctgc agtgatcaca acaaggtcag cgtctgcaca gtcagagtat tgagctgcat
    76681 agattttttt aggtgaagtg aaggcaaggg cgtgactaag gtcaagcgca tcaccaacag
    76741 ctttttcatg caattgtgga atttcgataa ttccaagctc ttgtgcaatt ccttggttaa
    76801 caagtgcaaa agcgtaagat gaacctacag caccatcacc gacaaggata acttttttgt
    76861 gttgtttagt tgaagtcatt gttttaaaca tctccttaat tttattaggg gattttccct
    76921 agacaacttc attctatcac ttttaaaaaa ctttgtcacg aatatgcctt atagttctcg
    76981 atgtaaacgt tttagtggtt tagaggctga aatagatggg aatttatggt ataatgttgt
    77041 tacttactaa ttgtgaaatg aggcatttat taatgcagga taaaaattta gtgaatgtca
    77101 atctgacaaa ggagatgaag gcaagtttta tcgactacgc catgagtgtt atcgtagcgc
    77161 gagctcttcc tgatgttcga gatggcttaa aacctgttca ccgtcgcatt ctctacggaa
    77221 tgaatgaatt gggtgtgacc ccagacaaac cccataaaaa atctgctcgt attacagggg
    77281 atgtcatggg taaatatcac ccacacgggg attcctctat ttatgaagcc atggtccgta
    77341 tggctcaatg gtggagctac cgttacatgc ttgtagatgg tcacgggaat tttggttcca
    77401 tggatggaga tagtgctgcc gctcaacgtt ataccgaggc acgtatgagc aagattgctc
    77461 tggaaatgct tcgtgatatc aacaaaaata cagttgattt cgttgataac tatgatgcca
    77521 atgaacggga acccttggtc ttgccagcgc gttttccaaa ccttttggtt aatggagcaa
    77581 ctggtatcgc ggttgggatg gcaaccaata ttccacctca taatctgggt gaaaccattg
    77641 atgcagtgaa gttggtcatg gataatcctg aagtgactac caaggacttg atggaagtct
    77701 tgcctggacc agattttcca actggtgctc ttgtcatggg gaaatcaggt atccataagg
    77761 cttatgaaac aggtaaaggt tcgattgtcc tacgttctcg tacagagatt gaaacgacta
    77821 agactggtcg tgagcgtatc gttgtaacag aatttcctta catggtcaat aaaaccaagg
    77881 tgcatgagca tattgttcgc ttggttcagg aaaaacgcat tgagggtatc acagcagtac
    77941 gtgatgagtc aaaccgtgaa ggtgttcgat ttgttattga agtcaagcgc gacgcctcag
    78001 ccaatgttat tctcaataac ctcttcaaaa tgacccaaat gcaaaccaat tttggtttca
    78061 atatgctcgc tatccaaaat ggtataccga aaattttgtc tcttcgtcag attttggatg
    78121 cttatatcga gcaccaaaaa gaagtggttg ttcgtcgtac acgttttgat aaggaaaaag
    78181 cggaagcgcg cgctcatatc ttagaaggtc tcttgattgc gctagaccat atcgacgaag
    78241 tgattcgtat catccgtgct agtgaaacgg atgcggaagc tcaagctgag ttgatgagca
    78301 agtttaagct ttctgaacgt caaagtcaag ctatccttga tatgcgtctt cgtcgtttga
    78361 caggtttgga acgcgataag attcaatctg agtatgatga cctcttggct ctgattgcgg
    78421 atttagcaga tattcttgct aagcctgaac gtgtttctca aattatcaaa gacgaattgg
    78481 atgaagttaa acgtaaattt tctgataagc gccgtacaga gttgatgatt ggacaggtct
    78541 tgagtctcga ggatgaggac ttgattgaag aatcggatgt cttgattacc ctttctaaca
    78601 gaggctacat taagcgtttg gatcaggacg agttcactgc tcaaaaacgt gggggtcgtg
    78661 gtgtccaagg aacgggagtg aaagatgatg actttgttcg tgagttagtg tcaactagca
    78721 cacatgatca tctgctcttc ttcacaaaca agggacgtgt ctatcgtctt aaaggttatg
    78781 aaattcctga gtatggtcgg actgccaaag ggctaccagt agtcaatctc ttgaaattgg
    78841 atgaagacga aagtattcag acggttatca atgttgagtc tgatcgcagt gatgatgctt
    78901 atctcttctt tacaacccgt cacggtattg tgaagagaac tagtgttaag gagtttgcca
    78961 atattcgtca aaatggtctc aaagcgctga atttaaagga tgaagatgag ttaatcaatg
    79021 tcttgttggc agaaggagat atggatatta tcattggtac caagtttggt tatgcagttc
    79081 gctttaatca atcagccgtt cgtggtatga gccgtatcgc cactggtgtg aaaggtgtta
    79141 accttcgtga aggagacaca gttgttggtg ccagcttgat tactgatcaa gatgaggttc
    79201 ttattatcac agaaaaagga tatggtaagc gtacagtcgc tactgaatac ccaacaaaag
    79261 gtcgtggtgg taagggaatg cagacagcta aaattaccga aaaaaatggc ttgctggccg
    79321 gtcttatgac tgttcaaggg gatgaggatt tgatgattat cactgataca ggtgtcatga
    79381 ttcgaaccaa tcttgccaat atttcacaaa caggacgtgc aactatggga gttaaagtaa
    79441 tgcgcctgga tcaagatgct cagatagtga ctttcacaac ggttgcggtg gcagaaaaag
    79501 aagaagttgg gacagaaaac gaaacagaag gtgaagcata atgtctcaaa aaaataataa
    79561 aaagaaaaac aagcgaaaaa atctgctgac aaatatccta gcaggatttc tgatattact
    79621 gtcactggct ttgattttta atactcaaat tcgaaatatt ttcatagtct ggaataccaa
    79681 taagtatcaa gttagccagg tatcaaaaga aaaattagaa gaaaatcagg atacagaagg
    79741 caattttgac tttgattctg tcaaagctat ctcttcggaa gctgttctaa cttctcaatg
    79801 ggatgctcaa aaattaccag ttattggggg aattgcaatt cctgaattgg aaatgaattt
    79861 gccgattttt aaaggacttg ataatgttaa tctcttctac ggagctggta caatgaaacg
    79921 cgagcaagta atgggagaag gaaattatag tctagctagt caccatatct ttggtgttga
    79981 taatgctaat aaaatgttat tttctccttt agataatgct aaaaatggca tgaagattta
    80041 tctaaccgat aaaaataaag tttatactta tgaaatacgt gaagtcaaac gtgtgacacc
    80101 ggatcgtgtt gatgaagttg atgatagaga tggggtcaat gaaatcacat tagtaacctg
    80161 tgaagacctt gctgctacag aacgtattat tgtcaaaggt gatttgaaag aaacaaaaga
    80221 ttattcacaa acatctgatg aaatcctaac agctttcaat caaccatata aacaatttta
    80281 ttaatacaaa tcagtgaaat catggatttc actgattttt taagattttc ataaaaatat
    80341 agtaaaatga aataagaata ggacgaatcg ttcaggacag tcaaatcgat ttctaacaat
    80401 gttttagaag tagaggtgta ctattctagt ttcaatctac tataaacttt tatgaaatac
    80461 agaaaacgct tcctaaaacc taaagtttgt gatataatta tcaagaaaaa agatttagga
    80521 gtttattatg atttcttcag aatttatctc aaagattgaa tttgcttgca ataagaaaga
    80581 aggtctttat agtcaaagca aatttaagta tgcgattcgt tcgatattcg caggtgcatt
    80641 tttaaccttc agtactgctg caggtgcagt tggggctgac ttgattaata aaattgcacc
    80701 aggtagtgga cgcttcctct ttccattcgt ttttgcttgg ggcttggcct acattgtttt
    80761 tttgaatgcc gagttggtca cttcaaacat gatgttcttg actgctggta gtttcttaaa
    80821 aaaaatctct tggagaaaaa cagctgagat tttactatac tgtaccttgt tcaaccttat
    80881 cggagccttg atagcagggt ggggctttgc tcattcggca gcctatgcga atctgataca
    80941 cgatagtttc atttcaggtg ttgttgagat gaagttaggc cgctcaaatg aattggtctt
    81001 gcttgaggcg attttggcaa atattttcgt aaatattgcg attctgtcat ttattttggt
    81061 caaagatggt ggtgccaaac tttggcttgt gttgtcagct atttacatgt ttgtattctt
    81121 aacaaacgag cacattgcgg cgaactttgc ttctttcgcg attgtgaaat tcagtgttgc
    81181 tgcggattca attgccaact tcggtgttgg aaatatgctt cgccactggg gtgtgacttt
    81241 catcggaaac tttatcggag gaggcctctt gatgggtctt ccatatgcct tcctcaataa
    81301 aaacgaagat acttatgtag attaagaaaa tgagcacgat tgagtcgtgc ttttttcatt
    81361 ttcaaaataa ggtaatagct atttcttata tcaaaatata gaaaactgat atttgtaaac
    81421 tataactcaa ggtgctacaa tatccttaat aaaatgatat ggaggtcacc ttatgacttg
    81481 tgattttaaa tttgaaactc tacaactaca tgctggtcaa gttgtggctc cagctactaa
    81541 gtctcgtgca gtgccgattt atcaaacaac atcttttatt tttgatgaca cgtaggaagg
    81601 tgctgatctg tttgccttga ggaaaccagg gaacatttat actcgtatca ccaatcctac
    81661 aacagctgcc cttgaaggtg gtgttgaagc gctagcaaca gcatcaggta tgactgcagt
    81721 gacttatacg attttggcgc ttgcccatgc tggtgaccat gtagtggctg cttcgactat
    81781 ttacggtgga accttcaatc ttttgaaaga accccttcct cgttatggta tcacaacaac
    81841 ctttgtcgat gttgataatt tggaggaagt agaagcagct atcaaagaca ataccaagct
    81901 tgtcttgatt gaaaccttgg gtaactcctt gattaatatt ccagacctgg aaaaactggc
    81961 agagattgct cataaacatc aaatcccact tgtgtcagac aatacttttg caatacctta
    82021 tttgattaac gtcttctctc atggcgttga cattgccatt cactctgcga ctaagtttat
    82081 cggtgggcat ggtacaacta ttggaggaat aattgtcgat agtggtcgtt ttgactggat
    82141 ggcttcaggg aaattccctc aatttgttga cgagggttca agctgccaca atttgagcta
    82201 tactcgtgat gtgggtgcag tagcctttat tatagctgtt cgagttcaat tgcttcgtga
    82261 tacaggtgca gccttgtcac cattcaatgc tttcctcttg ctacaaagac ttgaaaccct
    82321 ttcacttcgt gtggaacgcc atgtacaaaa tgctgagaca attgttgatt ttcttgtcaa
    82381 ccatcctaag gtagaaaagg taaattatcc aaaacttgca gatagtcctt attatgcctt
    82441 ggctgagaaa tacttgccaa aaggtgtcgg ttcaatcttt accttccacg tcaaaggtga
    82501 cgaggaagaa gcacgcaagg tcattgataa tttagaaatc ttttctgacc ttgcaaacgc
    82561 ggcagatgct aaatcgcttg ttgtccatcc agcaacaatc actcacggtc aattgtcaga
    82621 aaaagaccta gaagcagcag gtgtcacacc aaatcaaatc cacttgtcta tcggtcttga
    82681 aaatgtagaa gatttgattg aagacttacg cttggccttg gaaaaaattt aaagtaaaag
    82741 aagataaaca gtgggttttg actcactgtt tttgattttc cctcaggcat gatataatgg
    82801 ttacagaagt ctagaaagag gaatgtaatg aacgaaatca aatgtcccaa ctgtggggaa
    82861 gtctttacag taaatgaaag ccagtatgct gaacttttgt cccaagtgag aacggcagag
    82921 tttgataagg aactacacga taggatgagg caggaactgg ccttggctga gcaaaaggct
    82981 atgaatgagc aacagactaa actggctcag aaggatcaag aaattgcgca attgcagagt
    83041 caaatccaaa actttgatac agaaaaagaa ttggccaaga aagaagttga acagacaagc
    83101 catcaggcct tattggctaa ggacaaggaa gtacaggcct tggaaaacca gttggcgacc
    83161 ttgcgtttgg agcatgaaaa tcaattgcaa aagacccttt ctgacctaga aaaagaacgc
    83221 aatcaggtca aaaatcagct cctactgcaa gaaaaggaaa atgagttgtc tttggcttct
    83281 gttaagcaaa actacgaagc ccagctcaaa gcagccagtg aacaagtcga gttttataag
    83341 aattttaagg ctcaacaatc tacaaaagcg attggggaaa gcctagaaca gtatgcagag
    83401 agtgagttta acaaggttcg tagtttcgcc tttccaaatg cttactttga gaaggataac
    83461 aaggtctctt cgcgtgggtc taaaggggac tttatcttcc gtgagtgtga tgaaaatgga
    83521 gttgaaatca tttctatcat gtttgagatg aaaaacgaag cggacggaac agagaagaag
    83581 cacaagaatg cagattttta caaggaattg gacaaggacc gtcgggagaa gaactgtgag
    83641 tatgccgttt tggtgaccat gcttgaggct gataatgact actttaacac agggattgtt
    83701 gacgtcagtc acgagtatga aaaaatgtat gttgttcgtc ctcaattctt tatccaattg
    83761 attggtctct tacgtaatgc ggcgctaaat tccctaaaat acaagcagga gttggccttg
    83821 gttcgcgagc aaaatattga cattacgcat tttgaggaag acttggatgc ctttaagcta
    83881 gcttttgcta agaactataa ttcagcttcg actaactttg gaaaagctat tgatgaaatc
    83941 gacaaggcca tcaaacgcat ggaagaggtt aagaaattcc tgactacatc tgaaaaccaa
    84001 ctccgtctag ctaacaacaa attggaagat gtctctgtta aaaaattgac ccggaaaaat
    84061 ccaacaatga aagcgaagtt cgaagcattg aagggggagt agaaagcaaa aatgaacggt
    84121 attatcaact taaaaaaaga agcaggaatg acctcgcatg atgcggtttt taaactgcgt
    84181 aagattttgg gaaccaagaa aattggtcat ggcggaacct tggatccgga tgtggtgggt
    84241 gttttgccga ttgcggttgg caaggcgaca cgcatggtcg agtttatgca ggacgagggt
    84301 aagatctatg agggggaaat cactctgggc tattccacga cgactgagga tgctagtggg
    84361 gaagtggtcg cagaaacccc tgttttgtct cccttggatg aaaagcttgt tgatgaagcg
    84421 attgctagct tgactgggcc tattacccag attcccccta tgtattcggc agttaaggtt
    84481 aatggtcgca agctctatga gtatgcgcgt gctggtcagg aagtggagcg tccagaacgt
    84541 caggtgacca tttatcaatt tgagcgaaca agtccgattt cttatgatgg ccaacttgcc
    84601 cgattcactt ttcgtgtaaa atgcagtaaa gggacttaca tccgtacttt gtcagttgat
    84661 ttgggtgaaa agcttggtta tgcggctcat atgtcccatt tgactcgtac tagtgctgct
    84721 ggcttacaat tagaagatgc tcttaccttg gaggaaattg ctgaaaaagt agaggctggg
    84781 caattagatt ttctccatcc tttagagatt gggacaggtg accttgtcaa agttttccta
    84841 actccagaag aggctacaga agttcgcttt ggtcgtttta ttgagctaga ccaaacggac
    84901 aaagaactgg ctgcctttga agatgataaa ttgttagcca ttctagaaaa acggggcaat
    84961 ctctataagc caaggaaggt ttttagctag atcgtttagg aataaaaatc gggtgataga
    85021 taacaattgc ttgataaaac cccatactaa tagtagaatg gttttgggaa ttataatatt
    85081 ccaattgttg cgagttgtag gtactcaaat aatctatata gaaatttaga ggtgtgaaat
    85141 gaagcaattt aaaattcttt cagataaata tttagagtcc attacaggtt ctggtgggaa
    85201 cttaggccca ggatttggtg tgataattcc atgatgcgaa atgagtttcg agaaagggtg
    85261 gagcaacttc ttcaacaaaa agaaataaat gaaaatagtg agttgagtca cctgtttcgt
    85321 cttgctatac aaaatttaga cagaaatgaa aaacaccaat cggtcatggc caatttgagt
    85381 caagggttgt cactttacct catgacgcat cattaccagg cacctaagtc tgtcattgat
    85441 tttagtttat ggattgccaa agctcctagc caggaaagag ggaggctggc tttcttgcag
    85501 atgcttgctc aaatcctaca gggctttcgt taaaactgtc gaacatcaga gggaagactc
    85561 tggtgttttt tgctgatgag actataaatt ttgtaaaaaa tgtgatagaa tagacgacgg
    85621 ataaaataac ggaggatagc atgcaaaata gaccaatcat tattggagtg acaggtggtt
    85681 ctggtggtgg taaaaccagt gtttcaagag ccattttatc gcattttcct gatgaaaaga
    85741 tttccatgat tgagcatgat tcatactaca aggatcagtc tcatttgacc tttgaagagc
    85801 gtgtcaaaac caactatgac catccttttg cctttgatac agacttgatg atcgagcaga
    85861 ttaaggaatt gttggcaggg cgtccggtgg acatcccgac ctacgactat acagagcata
    85921 cacggagtag caagacctat cgtcaggagc ctcaagatgt ctttatcgtt gagggcattt
    85981 tggtcttgga ggacaagcgt ctgcgcgatt tgatggatat caagattttt gtggatacgg
    86041 atgacgatgt gcgtattatt cgtcgtatca agcgtgatat ggaggagcgt ggccgtagcc
    86101 ttgatagcgt tattaaccag tacttaggtg tggtcaaacc aatgtaccac cagtttatcg
    86161 agtcaactaa gcgttatgct gatatcgtca ttcctgaagg ggttagcaat accgtggcta
    86221 tcgacctgtt gacgaccaag attgcaaaga ttttggaaga agctcgaaac agcaaataat
    86281 cacatgtgga ggccttgcct cctttttcta tttttccctc ataatggtac ataaatggag
    86341 atttttaggc atatttttgg tataataata cccataaaag agcaagtaaa tgaatagtag
    86401 gtggagatgg aaaagtattt atcggtaaca actttgacca aatatctgaa aatgaaattc
    86461 gataaagacc catacttgga acgggtctat ttaactggtc aagtttccaa ctttcgtaaa
    86521 cgacctactc accaatattt ctccctaaag gatgaccatg cagttattca agcgaccatc
    86581 tggtctggga tttatcagaa attagggttt gacctggaag aaggaatgaa gatcaatgtg
    86641 attgggcgtg tacaggtcta tgaaccaagt ggtagctact ccatcatcat tgaaaaagct
    86701 gagcctgatg gggttggggc gcttgcgatt cagtttgaac aacttaagaa aaaattgaca
    86761 gaagaaggcc tgtttcaaga acgcttcaag caagctctac cccaattttc taagagaatt
    86821 ggtgtagtaa ccagccgtag tggagccgtt attcgagata ttatcacgac cgtcagcagg
    86881 cgattcccag gtgttgacat ccttctttat ccgaccaagg ttcaaggtga aggggctgcg
    86941 gaggaaattg ctagaaatat tgcgcgtgct aatcaacggg acgatttgga tttgctcatt
    87001 attggtcgtg gaggtggttc tattgaggat ctctgggcct ttaacgaaga aattgtggta
    87061 cgagctattt ttgaatctcg tttgccagtt atctctagtg tggggcatga gacggatgtg
    87121 accttggcag attttgtggc agatcgacgc gctgcaacgc caacagcggc ggctgaactg
    87181 gcaacacctg tgaccaagtt ggatgtatta gctcatttgc aaaatcagga aaaacggatg
    87241 gtaacggcag tccgaaatgt tctatctaag aaacaagagg ctttgaaaaa atgcagtcag
    87301 tctgttatct ttagacaacc tgagcgcttg tatgacggtt atttgcaacg cttggaccaa
    87361 ctgcaactgc gtttgaaaca aagtttgcga actcggattt ctgataacaa acaattagtt
    87421 caatcaagaa ctcatcaatt agtacaatta tcacctgtta ccaaaatcca acgctatcaa
    87481 gaccgtttag gacagttgga caagctctta ggtagccaaa tggcgttagt ttatgacgcc
    87541 aaggttgctg aggccaagcg actttcggaa gctttgctca tgttggatac tagccgaatc
    87601 gtggcgcgtg gttatgctat tgtcaaaaaa gaagagtccg ttgtagattc ggttgagagt
    87661 ttgaagaaaa aagaccaagt aacgcttttg atgcgagatg gtcaagtaga attagaggtt
    87721 aaagatgtca aaacaaaaga aatttgagga aaatctagca gaactggaaa ccattgtcca
    87781 aagtttggaa aatggtgaaa ttgctctgga agatgcgatt actgcctttc aaaagggcat
    87841 ggtcttgtca aaagagctcc aagctacgct ggacaaggct gaaaagacct tggtcaaggt
    87901 catgcaagaa gacggaacag aaagtgattt tgaatgaaaa agcaagaaaa attagctctt
    87961 gtcgagtcgg ctttggaaga tttttatgga gaccagcagt ttgcctctag tttacgggag
    88021 tctgttctct attctattca tgctggtggc aagcgtattc ggccttttct cttgttagaa
    88081 gttctggaag ccttgcaggt taccatcaaa cctgctcacg cgcaggtagc tactgccttg
    88141 gagatgattc atacagggag cttgattcac gatgaccttc ctgctatgga tgatgacgat
    88201 tatcgaagag ggcggttaac caatcacaag aaattcggtg aagctatggc cattttggct
    88261 ggagatgcct tattcttaga ctcatatgcc ttgattgcgc aggcagattt gccaagtcag
    88321 atcaaggtgg acttgattgc caacttatcc cttgcttcag gtagtctggg tatggtggca
    88381 gggcaagttt tggatatgga gggcgaacac cagcacttgt ctttggaaga acttcagact
    88441 attcatgcca ataagactgg gaagttacta gcctatccct tccaagcggc agctattata
    88501 gctgaattgt cacctgaaat gcaggtgaag ctgaaaactg tgggtgaatt gattggactt
    88561 gcttttcaag tcagggatga tgtactggat gtgacagcta gttttgagga aatcggcaag
    88621 acacctcaaa aggatctgca ggcagaaaaa tcaacctatc ctgccctgtt gggcttggaa
    88681 gagtccattg ccttttgtaa ccaaaccctg gatcaagcta atgaaaaatt agaagaaatt
    88741 gcccagcagc ttccctttga aacagaatcg attgtaagtg tagtagaaag tttgagaatc
    88801 aatggctaag gaaagagtgg atgtactagc ttataaacag gggttgtttg aaacgagaga
    88861 gcaggccaag cgaggtgtga tggctggcct agtcgtagca gtccttaatg gagaacggtt
    88921 tgacaagcca ggagagaaaa ttccagatga caccgaatta aaactcaagg gggagaaact
    88981 caagtatgtc agccgtggtg gtttgaaact ggaaaaggcc ttgcaggtct ttgatttgtc
    89041 ggtggatggc gcgactacga ttgatatcgg ggcctctact ggaggtttta ccgatgtcat
    89101 gctacagaat agtgccaagt tggtctttgc agtcgatgtt ggtaccaatc agttggcttg
    89161 gaaattacgc caagacccac gagttgtcag catggagcag ttcaatttcc gctatgctga
    89221 aaagactgat ttcgagcagg agccgagctt tgccagtatt gatgtgagtt tcatttccct
    89281 tagtctgatt ttgccagcct tgcaccgtgt cttggctgat caaggtcagg tggtagcact
    89341 tgtcaaacct cagtttgagg caggacgtga gcagattggg aaaaatggaa ttattcgaga
    89401 tgctaagatt catcagaatg tccttgaatc tgtaacagct atggcagtag aggcaggttt
    89461 ttcagtcctt ggcttggact tttctcccat ccaaggtgga catggaaata ttgaattttt
    89521 agcgtatttg aaaaaagaaa agtcagcaag caatcagatt cttgctgaga ttaaagaggc
    89581 agtagagagg gcgcatagtc aatttaaaaa tgaataaaaa agaaagactt gaaaaaatta
    89641 gaagattggt gacagattat caaatcggca cgcaagaaga aattgtagaa catttgaaag
    89701 aagcaggtat cactgccact caggcgacgg tatcccgaga tatcaaagag ttaggtattg
    89761 tcaaaattcc tttgagagac aacacctatg tctacgaatt gccaaaatca atcgtaaaaa
    89821 gtctgcaact ggctgaagac aatatcgaat cggctgaatt gatggataag atgatcaatc
    89881 tccaagttat tccaggaaat acggcttttg taaaagctca gttaatcgag acttttgcag
    89941 acaagatttt tagttgtttg actgatgata gctcgatttt agtcattgcc agaagtggaa
    90001 gtctagcaga ggaaatcttt gaacaagtaa aaaattggta ggtctatatg ttacttgaaa
    90061 tttcgataaa aaactttgcc attattgagg ctatttccct caattttgaa aaggggatga
    90121 ctgtcctgac tggtgaaacg ggtgcaggga agtcgattat cattgatgcc atgaatatga
    90181 tgttgggagc tcgtgcgacg acagatgtta ttcgtcatgg tgcaccaaag gcagagattg
    90241 aggggctttt ctcagttgag aatagtcgcc ttttacagga aatttttgat gagcaaggtt
    90301 tagaattagg tgatgaaatt atcatccgtc gggaaatctt gcaaaatggt cgtagtatca
    90361 gccgtgtaaa tggtcagatg gttaatctgt ctgttttgcg aactattggg caacatcttg
    90421 tagatattca tggtcagcat gaccatgagg agttaatgcg tccccaactg catatccaga
    90481 tgttggatga atttggtgat gccgcttttt gggacttgaa agaaacctat caaacgagtt
    90541 ttgatgccta tcggaaaatg cgcaagcagg ttctggaagt caagaaaaac caacaggaac
    90601 acaaggcacg tatcgaaatg ttggaatttc aaatggcaga gattgaggca gcaaacttgc
    90661 aggctggaga agacttggat ctcaatcaag agcgagataa actcctcaac cacaaaaata
    90721 ttgcggatac actgaccaat gcctacagta tgttggacaa tgaagatttt tcaagtctgg
    90781 ccaatgttcg ttcagccatg aatgacatgg aaagtgtcga agagtatgac cctgaatacc
    90841 gtgaaatttc aagctctctg tctgagacct actatgtttt agaagacatt agcaaacgtt
    90901 tggaagctat cattgaggac cttgattttg atggcaatcg cctcatgcag gttgagaatc
    90961 gtttggacct ccttcatact attactcgta agtatggtgg gactgttgat gatgttttgc
    91021 tttattttgc caagattacg gaagaataca atctcttgac aggcaataat ctttcgtctg
    91081 aggacatgga agcagagctt aagaagttgg aagtcaatct tgtcaatttg gcaggtcaac
    91141 ttgcttctgc tcgtcataat ttggctcagc aactcgaagc tgagattaaa caagaactgc
    91201 aagatcttta tatggaaaaa gcccagtttc aggttcgttt tagtaaggga aaattcagtc
    91261 gtgagggaaa tgaaatggtt gagttttata tttcaaccaa ccctggagaa gactttaaac
    91321 ccttggttaa ggttgcttct ggaggggaat tatctcgtct catgttagcc attaagtctg
    91381 ccttttcacg taaagaaggc aagactagca ttgtctttga tgaagtggat acgggagttt
    91441 caggtcgtgt tgctcaagct attgctcaga aaattcataa aattggtcag catggtcagg
    91501 ttttggctat ctcccatttg ccacaagtaa ttgcgattgc agattatcaa ttctttattg
    91561 agaagattag taatgaccat tcaacggttt cgactgttcg tctcttgacg gtcgaagagc
    91621 gagtggagga agttgccaag atgttggcag gtgatgatgt gacagaagca gccctgacgc
    91681 aagccagaga attgttgaga aacagggaga aataagatga cagattatta tgtaattgga
    91741 gatgttcacg gaaaagctgg gatgctggaa gaccttctta aaacctggga tggtcagacc
    91801 cagttgctct ttctaggtga tttgattgac agaggtgagg atagtcaccg tgttcttgaa
    91861 atggtcaagg acttggtgga caatcaaggg gctatctgtt tgtctggaaa ccacgagtat
    91921 atgtttttga cttggctaga tgacccagaa gaaagttatg accattatcg tcgcaatggt
    91981 ggagatacaa ccattaactc tatcctaggt cgtcccttgg atgcaccagt tgatggagta
    92041 gaagatgcca agcgggttgc cgctgaagcg gcagacttgg tcgaattcat tcgtcaaatg
    92101 ccatttgtag tagagacaga caagtatatc tttgttcacg caggtattga tttgaccttg
    92161 gatgactggc atgaaacaac agattataaa aaagtatggc ttagaaaacc attccacgga
    92221 gctgaaaatc atactggaaa aaccattgtc ttcggtcata caccggtcta tggtttgtta
    92281 cagcaagaac gcggtacatc tgagctttgg actacagaag atggcaagat tggaatggat
    92341 ggaggagctg tttatggtgg tgtccttcac gggattgtct ttacagacca aggaatgaca
    92401 gaacaccact ttatcgaaaa tgacggcttt gtcgctgaag attagtactc ctagcagggt
    92461 atggtcttgt caaaatatca aaaacaattt ataataaata gataccctga aaggaagaga
    92521 atcatgaact tagaagaatt gaaaaaacga caggagaaga tccgtaactt ctctattatc
    92581 gcccatattg accatggaaa atcaactcta gcagaccgca ttttggaaaa aacagagacg
    92641 gtttcaagtc gtgaaatgca ggcccagctt ttggatagca tggagctaga gcgggaacgt
    92701 ggaattacta ttaagttgaa tgccatcgag ttgaattaca ctgcaaaaga tggggaaact
    92761 tatattttcc atttgattga cacaccaggg cacgttgact ttacctatga agtttcacgt
    92821 tcgctagctg cctgtgaggg tgctattttg gtggtcgatg cggctcaagg aattgaggct
    92881 caaactcttg ccaacgttta tctggctttg gataatgatt tggaaatcat gcctatcatt
    92941 aataaaattg acctgccggc tgcagatccg gagcgcgtgc gtacagagat tgaagatgtg
    93001 attggtttgg atgccagtga agcagttttg gcttctgcca aggctggtat tgggattgaa
    93061 gaaatcctcg agcaaattgt agaaaaagta ccagcaccaa cgggtgatgt gacggcgcca
    93121 cttaaggcct tgattttcga ctctgtttac gatgcttacc gtggggttat cctccaagtg
    93181 cgtgtcatgg acggagtggt caaacctggt gataagattc agctcatgag caatagtaag
    93241 acctttgatg tggccgaagt cggtattttt acaccaaaag cggttggtcg tgatttcctt
    93301 gcgactggtg atgttggtta cattgcggcg tctatcaaga cggttcagga tactcgtgtg
    93361 ggtgataccg ttaccttggc aaccaatcct gcggcagaac cattacatgg ttataagcag
    93421 atgaatccta tggtctttgc gggtctctac ccaatcgaat caaacaaata caatgacctg
    93481 cgtgaagcgc ttgaaaaatt gcaactgaat gatgctagtc ttcagtttga accagaaaca
    93541 tctcaggcac ttggatttgg tttccgttgt ggatttcttg gacttctcca tatggatgtt
    93601 atccaggaac gtttagagcg tgagttcaat attgacctca tcatgacagc tccgtctgtt
    93661 atttacaaag ttaatttgac cgacggtgag tctatggatg tgtctaaccc atctgagttt
    93721 ccagacccaa ctaagattgc gaccattgaa gagccttatg tcaaggcgca aatcatggta
    93781 ccacaggagt tcgtcggagc agtaatggag ctagctcagc gtaagcgtgg ggactttgtg
    93841 actatggact atattgatga taaccgtgtc aatgttatct atcaaattcc tcttgctgaa
    93901 attgtctttg acttctttga taaacttaag tcttcgacac gtggttatgc aagctttgac
    93961 tacgaattgt cagaatatcg cccatctaag ctggtgaaaa tggatatcct tctcaatgga
    94021 gataaggtgg atgccctcag ctttatcgtt cacaaggact ttgcctacga acgtgggaaa
    94081 ctcatcgttg ataaactcaa gaaaatcatc cctcgccaac aatttgaagt tccaatccaa
    94141 gcggctattg gacacaagat tgtcgctcgt actgatatca aggcccttcg taagaacgta
    94201 cttgctaaat gttatggtgg tgacgtttct cgtaagcgta aactccttga aaaacaaaaa
    94261 gctggtaaga aacgcatgaa atccatcgga tcagttgaag ttccgcaaga agccttcctc
    94321 agcgtcttga gtatggatga agaataagtt atcagaaatg cctttccttg ttcacaggaa
    94381 atttatataa gaatcaatag taaagcaggc ttagatggtc tgctttttta gtttttatac
    94441 tcttcgaaaa tctcttcaaa ccacgtcagc gtcgccttac tgtatgtatg gttactgacc
    94501 tcgtcagttt catctacaac ctcaaaactg tgttttgagt aacctgcggc tagcttccta
    94561 gtttgctctt tgattttcat tgagtattag aacagaaaaa tgcttggagt atttgtttgt
    94621 gtgtttattt ttatataaca aactataaac aaaacaaaaa tataaaaaaa gagacaaaaa
    94681 ataatagaaa gtaattaaca acgatttcat atagtgttat acttatagca taaagttaat
    94741 ggaaagaagg gaaaacctta tggtattaga ttatttcttt gacaaaaacc ttgtgttttg
    94801 cttagaagcg gataatcaag aataactttt tgatcaggta gcaagcttgt tggaagaacg
    94861 agaaattgtc actccaactt atcgtgaagc cttgatcacg cgtgaaaagt catttccaac
    94921 tggtttagat atggaatttc taggaaagga cttgcaaatg taatgattcc tcacacagat
    94981 attgttcata atctagctga gaaagtggtg gttgttcgat tagagaaacc ggtgactttc
    95041 cataatatga ttgcgccagg taaggaagta gaagtatcct tgctcttctt tatcatcaat
    95101 aactcaagtt caagtcaaac aaatattctg gctcagttga tggacttttt cacaggaaat
    95161 ggacatcttg aagacctatc aaaaatttcc gaaccagaaa aactttatgc ttacattgct
    95221 gaagcaaccg cttaatcttg tctattaaaa aataaaatcg gaggaaatct aaatgattaa
    95281 aattcttgct gcctgcggtg caggtgttaa ctcaagtcac caaattaaaa gtgctctaga
    95341 agaagaactt tcaaaccgtg gttatgatgt tcactgtgat gcagtcatgg tgaaagatgt
    95401 aaacgaagac cttatgaaag gttacgatat ctttacacca atcgctgcaa cagaccttgg
    95461 ttttgaacca ggtatcccag ttatcgaagc tggaccaatc ttattccgta tcccagcaat
    95521 gagcgttcca gtatttgaca atattagact tcctgcgaaa caaaatatgg tatagtagtt
    95581 cca
//
LOCUS       DBERPV010000004        84517 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.04, whole genome shotgun sequence.
ACCESSION   DBERPV010000004 DBERPV010000000
VERSION     DBERPV010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 84517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 84517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..84517
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.04"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            371..598
                     /locus_tag="ACL8C7_000377"
     CDS             371..598
                     /locus_tag="ACL8C7_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394639.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            886..3783
                     /gene="nanA"
                     /locus_tag="ACL8C7_000378"
     CDS             886..3783
                     /gene="nanA"
                     /locus_tag="ACL8C7_000378"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HGS1394640.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGNRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGNQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NKRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHNGKEYIILSNAGGPNRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            4798..5250
                     /locus_tag="ACL8C7_000379"
     CDS             4798..5250
                     /locus_tag="ACL8C7_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGS1394641.1"
                     /translation="MIITKISHLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            5269..6606
                     /locus_tag="ACL8C7_000380"
     CDS             5269..6606
                     /locus_tag="ACL8C7_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS1394642.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            6685..7569
                     /locus_tag="ACL8C7_000381"
     CDS             6685..7569
                     /locus_tag="ACL8C7_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS1394643.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTIFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            7569..8402
                     /locus_tag="ACL8C7_000382"
     CDS             7569..8402
                     /locus_tag="ACL8C7_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS1394644.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAVFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNRIASGLSEGSV
                     K"
     gene            8420..10513
                     /gene="nanB"
                     /locus_tag="ACL8C7_000383"
     CDS             8420..10513
                     /gene="nanB"
                     /locus_tag="ACL8C7_000383"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HGS1394645.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSTIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            10525..11628
                     /locus_tag="ACL8C7_000384"
     CDS             10525..11628
                     /locus_tag="ACL8C7_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGS1394646.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            11802..12500
                     /locus_tag="ACL8C7_000385"
     CDS             11802..12500
                     /locus_tag="ACL8C7_000385"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HGS1394647.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            12519..14036
                     /locus_tag="ACL8C7_000386"
     CDS             12519..14036
                     /locus_tag="ACL8C7_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGS1394648.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADLAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFLGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            14161..15489
                     /locus_tag="ACL8C7_000387"
     CDS             14161..15489
                     /locus_tag="ACL8C7_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS1394649.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            15741..16607
                     /locus_tag="ACL8C7_000388"
     CDS             15741..16607
                     /locus_tag="ACL8C7_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS1394650.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            16623..17462
                     /locus_tag="ACL8C7_000389"
     CDS             16623..17462
                     /locus_tag="ACL8C7_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS1394651.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            17735..18187
                     /locus_tag="ACL8C7_000390"
     CDS             17735..18187
                     /locus_tag="ACL8C7_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGS1394652.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKEEAVAFDEASDIG
                     FVHCYEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            18284..18628
                     /locus_tag="ACL8C7_000391"
     CDS             18284..18628
                     /locus_tag="ACL8C7_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394653.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMSWIIRGIVNGLIGRYIKLGTY
                     AAKYGISMARSILSRAAATAAARVGLLTKIFGWILRIAVLAADVYGNFANNIAVAWDA
                     HDKIPNNGRINF"
     gene            18638..18847
                     /locus_tag="ACL8C7_000392"
     CDS             18638..18847
                     /locus_tag="ACL8C7_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394654.1"
                     /translation="MKALCIFLLNMLAWTVLAMIIRGGLDGFNEHTWSTILIASLSGI
                     YDYKPIDKNRKKSKRKNRFVHGRDL"
     gene            18905..19549
                     /locus_tag="ACL8C7_000393"
     CDS             18905..19549
                     /locus_tag="ACL8C7_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HGS1394655.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSAFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            19718..20635
                     /locus_tag="ACL8C7_000394"
     CDS             19718..20635
                     /locus_tag="ACL8C7_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HGS1394656.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            20653..21537
                     /locus_tag="ACL8C7_000395"
     CDS             20653..21537
                     /locus_tag="ACL8C7_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGS1394657.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(21553..22404)
                     /locus_tag="ACL8C7_000396"
     CDS             complement(21553..22404)
                     /locus_tag="ACL8C7_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGS1394658.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            22604..24661
                     /gene="pbp2b"
                     /locus_tag="ACL8C7_000397"
     CDS             22604..24661
                     /gene="pbp2b"
                     /locus_tag="ACL8C7_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HGS1394659.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANDGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSELTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            24672..25268
                     /gene="recR"
                     /locus_tag="ACL8C7_000398"
     CDS             24672..25268
                     /gene="recR"
                     /locus_tag="ACL8C7_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HGS1394660.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            25444..26487
                     /locus_tag="ACL8C7_000399"
     CDS             25444..26487
                     /locus_tag="ACL8C7_000399"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HGS1394661.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLVYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPKLIERLVDL
                     AKESFDKREAHLI"
     gene            26571..27944
                     /gene="murF"
                     /locus_tag="ACL8C7_000400"
     CDS             26571..27944
                     /gene="murF"
                     /locus_tag="ACL8C7_000400"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HGS1394662.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTSFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIHQAFQGLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSIQLHNQMILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVE
                     SLENEDK"
     gene            27931..28542
                     /locus_tag="ACL8C7_000401"
     CDS             27931..28542
                     /locus_tag="ACL8C7_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase N-terminal domain-containing
                     protein"
                     /protein_id="HGS1394663.1"
                     /translation="MKTSDFVKYLQRMIAITDTGLTFTKDPFDRERYEDLRDLLSEML
                     NQASDLDSEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDPLPNLSEKRITKEQIEILWQVYQGQREQYLD"
     gene            28633..29337
                     /locus_tag="ACL8C7_000402"
     CDS             28633..29337
                     /locus_tag="ACL8C7_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HGS1394664.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            29556..30929
                     /gene="ftsA"
                     /locus_tag="ACL8C7_000403"
     CDS             29556..30929
                     /gene="ftsA"
                     /locus_tag="ACL8C7_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HGS1394665.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            30946..32205
                     /gene="ftsZ"
                     /locus_tag="ACL8C7_000404"
     CDS             30946..32205
                     /gene="ftsZ"
                     /locus_tag="ACL8C7_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HGS1394666.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            32210..32881
                     /locus_tag="ACL8C7_000405"
     CDS             32210..32881
                     /locus_tag="ACL8C7_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HGS1394667.1"
                     /translation="MNVKENTELVFREVGEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLSLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            32891..33430
                     /locus_tag="ACL8C7_000406"
     CDS             32891..33430
                     /locus_tag="ACL8C7_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HGS1394668.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            33430..33693
                     /locus_tag="ACL8C7_000407"
     CDS             33430..33693
                     /locus_tag="ACL8C7_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HGS1394669.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            33690..34475
                     /locus_tag="ACL8C7_000408"
     CDS             33690..34475
                     /locus_tag="ACL8C7_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HGS1394670.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEYL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            34484..35272
                     /gene="divIVA"
                     /locus_tag="ACL8C7_000409"
     CDS             34484..35272
                     /gene="divIVA"
                     /locus_tag="ACL8C7_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HGS1394671.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            35620..38412
                     /gene="ileS"
                     /locus_tag="ACL8C7_000410"
     CDS             35620..38412
                     /gene="ileS"
                     /locus_tag="ACL8C7_000410"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HGS1394672.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELIYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEAQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIVEGPAPEAALSFEDVAFTVERATGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
     gene            38815..39195
                     /locus_tag="ACL8C7_000411"
     CDS             38815..39195
                     /locus_tag="ACL8C7_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394673.1"
                     /translation="MKLKRLALISGIVGLVGGILLLIGPFVLLGTAVNTAATTLNGGA
                     TAGAFSGVALLLNALKIANLVLGIIAIVYYKGDKRVGAAPSVLMIVSGGVSLIPFLGW
                     VGGILAIIGGSLFLATLKKFKSEE"
     gene            39729..40421
                     /locus_tag="ACL8C7_000412"
     CDS             39729..40421
                     /locus_tag="ACL8C7_000412"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HGS1394674.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFIGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            40474..42885
                     /locus_tag="ACL8C7_000413"
     CDS             40474..42885
                     /locus_tag="ACL8C7_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HGS1394675.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYGFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTQFE
                     REAFASFPDDLLVQCFTKEGLETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            43135..43836
                     /locus_tag="ACL8C7_000414"
     CDS             43135..43836
                     /locus_tag="ACL8C7_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1394676.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            43838..46546
                     /locus_tag="ACL8C7_000415"
     CDS             43838..46546
                     /locus_tag="ACL8C7_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGS1394677.1"
                     /translation="MIKRKTYWKDLIQSFTDSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDREIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQAQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLIAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(46642..47133)
                     /gene="tpx"
                     /locus_tag="ACL8C7_000416"
     CDS             complement(46642..47133)
                     /gene="tpx"
                     /locus_tag="ACL8C7_000416"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0016684 - oxidoreductase activity, acting
                     on peroxide as acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HGS1394678.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(47256..48185)
                     /gene="psaA"
                     /locus_tag="ACL8C7_000417"
     CDS             complement(47256..48185)
                     /gene="psaA"
                     /locus_tag="ACL8C7_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HGS1394679.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(48217..49065)
                     /locus_tag="ACL8C7_000418"
     CDS             complement(48217..49065)
                     /locus_tag="ACL8C7_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HGS1394680.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(49062..49784)
                     /locus_tag="ACL8C7_000419"
     CDS             complement(49062..49784)
                     /locus_tag="ACL8C7_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGS1394681.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            50075..51967
                     /gene="pepO"
                     /locus_tag="ACL8C7_000420"
     CDS             50075..51967
                     /gene="pepO"
                     /locus_tag="ACL8C7_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HGS1394682.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVATVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(52090..52719)
                     /locus_tag="ACL8C7_000421"
     CDS             complement(52090..52719)
                     /locus_tag="ACL8C7_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGS1394683.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            complement(53059..53301)
                     /locus_tag="ACL8C7_000422"
     CDS             complement(53059..53301)
                     /locus_tag="ACL8C7_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394684.1"
                     /translation="MTRFEEILEECKNPQDTFFYPLVYKENTYEKTAISIFALLMLGV
                     CCLFLFSQQSYKKLVQYYANDQNLPSRITYSEYSDK"
     gene            53712..55934
                     /locus_tag="ACL8C7_000423"
     CDS             53712..55934
                     /locus_tag="ACL8C7_000423"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HGS1394685.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRMIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            55964..56407
                     /gene="dtd"
                     /locus_tag="ACL8C7_000424"
     CDS             55964..56407
                     /gene="dtd"
                     /locus_tag="ACL8C7_000424"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HGS1394686.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELINNGPVTIILDTKKR"
     gene            complement(56879..57292)
                     /locus_tag="ACL8C7_000425"
     CDS             complement(56879..57292)
                     /locus_tag="ACL8C7_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394687.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFIIRLETSFEWLLLSGLIFFLA
                     QGLLLFLLIVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLRENYPDFYDKHISLWECL"
     gene            complement(57423..58130)
                     /locus_tag="ACL8C7_000426"
     CDS             complement(57423..58130)
                     /locus_tag="ACL8C7_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0034257 - nicotinamide riboside
                     transmembrane transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter family
                     protein"
                     /protein_id="HGS1394688.1"
                     /translation="MKKSLKIFATSKWFDLFGVALVVGIAIASGYLNSRLDKFVDWGP
                     WTALVPFGLISVTNVGISMLSTRFTGKLSKWGNYFSIVNTILSGAIDYILGNKAAIIT
                     YPVTFLIYTFAIKKWKASQEGRPNQMSQKQVKLAVIIISIIAFLFAFVTNYIGYEGKM
                     NLLAYVTTIAFALSLIANALNALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFY
                     ILNAIGALFVWNDEEVR"
     gene            complement(58247..58897)
                     /locus_tag="ACL8C7_000427"
     CDS             complement(58247..58897)
                     /locus_tag="ACL8C7_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HGS1394689.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     NFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            59009..59851
                     /locus_tag="ACL8C7_000428"
     CDS             59009..59851
                     /locus_tag="ACL8C7_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGS1394690.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADAQQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            59927..60364
                     /locus_tag="ACL8C7_000429"
     CDS             59927..60364
                     /locus_tag="ACL8C7_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HGS1394691.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            60433..60735
                     /locus_tag="ACL8C7_000430"
     CDS             60433..60735
                     /locus_tag="ACL8C7_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394692.1"
                     /translation="MYLVIEIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(60826..61899)
                     /locus_tag="ACL8C7_000431"
     CDS             complement(60826..61899)
                     /locus_tag="ACL8C7_000431"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HGS1394693.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYHAWKNR"
     gene            62055..62732
                     /locus_tag="ACL8C7_000432"
     CDS             62055..62732
                     /locus_tag="ACL8C7_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS1394694.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIGDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            62725..63699
                     /locus_tag="ACL8C7_000433"
     CDS             62725..63699
                     /locus_tag="ACL8C7_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HGS1394695.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(63748..65691)
                     /gene="thrS"
                     /locus_tag="ACL8C7_000434"
     CDS             complement(63748..65691)
                     /gene="thrS"
                     /locus_tag="ACL8C7_000434"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HGS1394696.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(65749..65925)
                     /locus_tag="ACL8C7_000435"
     CDS             complement(65749..65925)
                     /locus_tag="ACL8C7_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HGS1394697.1"
                     /translation="MTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENF
                     LSDKEKQLNVRTRK"
     gene            complement(65932..66072)
                     /locus_tag="ACL8C7_000436"
     CDS             complement(65932..66072)
                     /locus_tag="ACL8C7_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HGS1394698.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQ"
     gene            complement(66329..66703)
                     /locus_tag="ACL8C7_000437"
                     /pseudo
     CDS             complement(66329..66703)
                     /locus_tag="ACL8C7_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397621.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            66942..67571
                     /locus_tag="ACL8C7_000438"
     CDS             66942..67571
                     /locus_tag="ACL8C7_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HGS1394699.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGSGS
                     FYIDETKTTRLLDTSDFPEEFKPLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            67712..67981
                     /gene="rpsO"
                     /locus_tag="ACL8C7_000439"
     CDS             67712..67981
                     /gene="rpsO"
                     /locus_tag="ACL8C7_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HGS1394700.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            68796..69410
                     /locus_tag="ACL8C7_000440"
     CDS             68796..69410
                     /locus_tag="ACL8C7_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HGS1394701.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(69702..70451)
                     /locus_tag="ACL8C7_000441"
     CDS             complement(69702..70451)
                     /locus_tag="ACL8C7_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HGS1394702.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            70584..72920
                     /locus_tag="ACL8C7_000442"
     CDS             70584..72920
                     /locus_tag="ACL8C7_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGS1394703.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLARVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAVASILTSYMA
                     HSEDKNPTAHAIRQRFQGQVVYPMLSNLPFSSDRKWGAMELEGLGIVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLNY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRRSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEIATLTGQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            73022..73699
                     /locus_tag="ACL8C7_000443"
     CDS             73022..73699
                     /locus_tag="ACL8C7_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HGS1394704.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEEIDQVSVITIAGMGGCLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQNHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVPHVSK"
     gene            73686..74483
                     /locus_tag="ACL8C7_000444"
     CDS             73686..74483
                     /locus_tag="ACL8C7_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HGS1394705.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            74500..75603
                     /locus_tag="ACL8C7_000445"
     CDS             74500..75603
                     /locus_tag="ACL8C7_000445"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGS1394706.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGHLLVTRL
                     LEASQVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLVQDMEAYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPELAGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            75859..76878
                     /gene="galE"
                     /locus_tag="ACL8C7_000446"
     CDS             75859..76878
                     /gene="galE"
                     /locus_tag="ACL8C7_000446"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGS1394707.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTATLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            76880..77845
                     /locus_tag="ACL8C7_000447"
     CDS             76880..77845
                     /locus_tag="ACL8C7_000447"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGS1394708.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKNKVKRL"
     gene            complement(77896..78102)
                     /locus_tag="ACL8C7_000448"
     CDS             complement(77896..78102)
                     /locus_tag="ACL8C7_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HGS1394709.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            78154..78630
                     /locus_tag="ACL8C7_000449"
     CDS             78154..78630
                     /locus_tag="ACL8C7_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HGS1394710.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            78639..79310
                     /gene="cmk"
                     /locus_tag="ACL8C7_000450"
     CDS             78639..79310
                     /gene="cmk"
                     /locus_tag="ACL8C7_000450"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HGS1394711.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLVVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            79441..79779
                     /locus_tag="ACL8C7_000451"
     CDS             79441..79779
                     /locus_tag="ACL8C7_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HGS1394712.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLADGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            79782..80411
                     /locus_tag="ACL8C7_000452"
     CDS             79782..80411
                     /locus_tag="ACL8C7_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HGS1394713.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            80651..81802
                     /locus_tag="ACL8C7_000453"
     CDS             80651..81802
                     /locus_tag="ACL8C7_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGS1394714.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            82114..82863
                     /gene="truA"
                     /locus_tag="ACL8C7_000454"
     CDS             82114..82863
                     /gene="truA"
                     /locus_tag="ACL8C7_000454"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HGS1394715.1"
                     /translation="MTRYKATISYDGYAFAGFQRQPHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVAADFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            82853..83626
                     /locus_tag="ACL8C7_000455"
     CDS             82853..83626
                     /locus_tag="ACL8C7_000455"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HGS1394716.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGIPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            83604..84065
                     /locus_tag="ACL8C7_000456"
     CDS             83604..84065
                     /locus_tag="ACL8C7_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGS1394717.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNDWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            84296..84504
                     /locus_tag="ACL8C7_000457"
                     /pseudo
     CDS             84296..84504
                     /locus_tag="ACL8C7_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT        25378 a        15356 c        18855 g        24928 t
ORIGIN      
        1 gtcagtctta tctacaacct caaaacagtg ttttgagcat catgcggcta gcttcttagt
       61 ttgctctttg attttcattg agtataaaaa cagatgagtt tctgttttct ttttatggac
      121 tataaatgtt cagctgaaac tactttcaag gacattatta tataaaagaa ttttttgaaa
      181 ctaaaatcta ctatattaca ctatattgaa agcgttttaa aaatgaggta taataaattt
      241 actaacactt ataaaaagtg atagaatcta tctttatgta tatttaaaga tagattgctg
      301 taaaaatagt agtagctatg cgaaataaca gatagagaga agggattgaa gcttagaaaa
      361 ggggaataat atgatattta aggcattcaa gacaaaaaag cagagaaaaa gacaagttga
      421 actacttttg acagtttttt tcgacagttt tctgattgat ttatttcttc acttatttgg
      481 gattgtcccc tttaagctgg ataagattct gattgtgagc ttgattatat ttcccattat
      541 ttctacaagt atttatgctt atgaaaagct atttgaaaaa gtgttcgata aggattgagc
      601 aggaagtatg gtataaatag cataagctga tgtccatcat ttgcttataa agagatattt
      661 tagtttaatt gcagcggtgt cctggtagat aaactagatt ggcaggagtc tgattggaga
      721 aaggagaggg gaaaattggc accaatttga gatagtttgt ttagttcatt tttgtcattt
      781 aaatgaactg tagtaaaaga aagttaataa aagacaaact aagtgcattt tctggagtaa
      841 atgtcttatt tcagaaatcg ggatatagat atagagagga tcagtatgaa tcggagtgtt
      901 caagaacgta agtgtcgtta tagcattagg aaactatcgg taggagcggt ttctatgatt
      961 gtaggagcag tggtatttgg aacgtctcct gttttagctc aagaaggggc aagtgagcaa
     1021 cctctggcaa atgaaactca actttcgggg gagagctcaa ccctaactga tacagaaaag
     1081 agccagcctt cttcagagac tgaactttct ggcaataagc aagaacaaga aaggaaagat
     1141 aagcaagaag aaaaaattcc aagagattac tatgcacgag atttggaaaa tgtcgaaaca
     1201 gtgatagaaa aagaagatgt tgaaaccaat gcttcaaatg gtcagagagt tgatttatca
     1261 agtgaactag ataaactaaa gaaacttgaa aacgcaacag ttcacatgga gtttaagcca
     1321 gatgccaagg ctccagcatt ctataatctc ttttctgtgt caagtgctac taaaaaagat
     1381 gagtacttca ctatggcagt ttacaataat actgctactc tagaggggcg tggttcggat
     1441 gggaaacagt tttacaataa ttacaacgat gcacccttaa aagttaaacc aggtcagtgg
     1501 aattctgtga ctttcacagt tgaaaaaccg acagcagaat tgccaaatgg tcgagttcgc
     1561 ctgtatgtta atggtgtttt atctcgaaca agtctgaaat ctggcaattt cattaaagat
     1621 atgccagatg taacgcatgt gcaaatcgga gcaaccaagc gtgccaacaa tacggtttgg
     1681 gggtcaaatc tacagattcg gaatctcact gtgtataatc gtgctttaac accagaagag
     1741 gtacaaaaac gtagtcaact ttttaaacgc tcagatttag aaaaaaaact acctgaagga
     1801 gcggctttaa cagagaaaac ggacatattc gaaagcgggc gtaacggtaa accaaataaa
     1861 gatggaatca agagttatcg tattccagca cttctcaaga cagataaagg aactttgatc
     1921 gcaggtgcag atgaacgccg tctccattcg agtgactggg gtgatatcgg tatggtcatc
     1981 agacgtagtg aagataatgg taaaacttgg ggtaaccgag taaccattac caacttacgt
     2041 gacaatccaa aagcttctga cccatcgatc ggttcaccag tgaatatcga tatggtgttg
     2101 gttcaagatc ctgaaaccaa acgaatcttt tctatctatg acatgttccc agaagggaag
     2161 ggaatctttg gaatgtcttc acaaaaagaa gaagcctaca aaaaaatcga tggaaaaacc
     2221 tatcaaatcc tctatcgtga aggagaaaag ggagcttata ccattcgaga aaatggtact
     2281 gtctatacac cagatggtaa ggcgacagac tatcgcgttg ttgtagatcc tgttaaacca
     2341 gcctatagcg acaagggtga tctatacaag ggtaaccaat tactaggcaa tatctacttc
     2401 acaacaaaca aaacttctcc atttagaatt gccaaggata gctatctatg gatgtcctac
     2461 agtgatgacg acgggaagac atggtcagcg cctcaagata ttactccgat ggtcaaagcc
     2521 gattggatga aattcttggg tgtaggtcct ggaacaggaa ttgtacttcg gaatgggcct
     2581 cacaagggac ggattttgat accggtttat acgactaata atgtatctca cttaaatggc
     2641 tcgcaatctt ctcgtgtcat ctattcagat gatcatggaa aaacttggca tgctggagaa
     2701 gcggtcaacg ataaccgtca ggtagacggt caaaagatcc actcttctac gatgaacaat
     2761 aaacgtgcgc aaaatacaga atcaacggtg gtacaactaa acaatggaga tgttaaactc
     2821 tttatgcgtg gtttgactgg agatcttcag gttgctacaa gtaaagacgg aggagtgact
     2881 tgggagaagg atatcaaacg ttatccacag gttaaagatg tctatgttca aatgtctgct
     2941 atccatacga tgcataatgg aaaagaatac attatcctca gcaatgcagg tggaccgaat
     3001 cgtgaaaatg ggatggtcca cttggcacgt gtcgaagaaa atggtgagtt gacttggctc
     3061 aaacacaatc caattcaaaa aggagagttt gcctataatt cgctccaaga attaggaaat
     3121 ggggagtatg gcatcttgta tgaacatact gaaaaaggac aaaatgccta taccctatca
     3181 tttagaaaat ttaattggga atttttgagc aaagatctga tttctcctac cgaagcgaaa
     3241 gtgaagcgaa ctagagagat gggcaaagga gagatgggca aaggagttat tggcttggag
     3301 tttgactcag aagtattggt caacaaggct ccaacccttc aattggcaaa tggtaaaaca
     3361 gcgactttcc taacccagta tgatagcaag accttgttgt ttgcagtaga taaggaagat
     3421 atcggacagg aaattattgg tatagctaaa ggaagcatcg aaagtatgca taatcttcct
     3481 gtaaatctag caggtgccag agttcctggc ggagtaaatg gtagcaaagc agcggtgcat
     3541 gaagttccag aatttacagg gggagttaat ggtacagagc cagctgttca tgaaatcgca
     3601 gagtataagg gatctgattc gcttgtaact cttactacaa aagaagatta tacttacaaa
     3661 gctcctcttg ctcagcaggc acttcctgaa acaggaaaca aggagagtga cctcctagct
     3721 tcactaggac taacagcttt cttccttggt ctgtttacgc tagggaaaaa gagagaacaa
     3781 taagagaaga attctaaaca tttgattttg taaaaataga aggagatagc aggttttcaa
     3841 gcctgctatc tttttttgat gacattcagg ctgatacgaa atcataagag gtctgaaact
     3901 actttcagag tagtctgttc tataaaatat agtagattga aataagatgt gaacaactct
     3961 atcaggaaag tcaaattaat ttatagaaaa attttagcag tcaaggtgta ctgttataga
     4021 ttcaatatat tatgtgacta ttaaccttct cttctcctaa aattgacttt cttgttttct
     4081 tatcttgtcc actcgaaaca agtattgtaa gaatttgatt atttttgaaa gtacttttaa
     4141 tatacttgat atagttaaaa aagatttgaa actaaattcc aaattagaaa aagacttgaa
     4201 atactaaaaa aaaaaagtat actctaattg aaaacggtaa caaaactaat ttagagaatg
     4261 aaatatagag tatttctctc ttaaaagttt ttggtgaaac gagatgtaga aaggagattt
     4321 agccaaagag tctattagtg ctagaataat agattagaat tattttagaa aaacgaagtg
     4381 agcagcttat aaattcaagt ccccaaatag attcatacta gtatcttttg caaaaaataa
     4441 agggcgactt ccgtcatgaa tatcaatttc atctataagg aaggtagcta attgaactaa
     4501 cttatttatt ctgtttgtcg ctagaaaaat cagacctcct tgtgaagatt gaggagatac
     4561 tgaatgaaaa tcaaagaaga aactagcaag ctagtagcag attgcccaaa acaccgcctt
     4621 gaggttgtag ataagactga cctatataat ccaaggtgaa gcgactgtgg tttgaagaga
     4681 ttttcaaaga gtataggcta gagagtagtg tttttatgtc cttctagtag aaaatgctag
     4741 acagaagaat ggggaacttg gataggaaaa atagattgag aaaggaggtt agaagagatg
     4801 attattacaa aaattagcca tttaggaact tatgtgggag taaatccaca ttttgcaaca
     4861 ttaatagatt ttctagaaaa aacaggacta gaaaatttaa cagaaggttc gattgctatc
     4921 gatggtaatc gattgtttgg gaattgcttt acttatctag cagatggtca agcaggggct
     4981 ttctttgaaa cacaccaaaa atatttggat attcatttag ttttggaaaa cgaagaagcc
     5041 atggctgtta catcgccgga aaatgtaagc gttacccaag aatatgatga agagaaagat
     5101 attgaattat acacagggaa agtggaacag ttggttcatt tgagagctgg tgaatgcctc
     5161 atcacttttc cagaagattt acatcaaccc aaggttcgta taaatgatga acctgtgaaa
     5221 aaagttgtct ttaaagttgc gatttcttaa tgtagaaaga gaagaacgat gaaaaaaatg
     5281 agaaagtttt tatgtctagc tggaattgcg ctagcggctg ttgccttggt agcttgttca
     5341 ggaaaaaaag aagctacaac tagtactgaa ccaccaacag aattatctgg tgagattaca
     5401 atgtggcact cctttactca aggaccccgt ttagaaagta ttcaaaaatc agcagatgct
     5461 ttcatgcaaa agcatccaaa aacgaaaatc aagattgaaa cattttcttg gaatgacttc
     5521 tatactaaat ggactacagg tttagcaaat ggaaatgtgc cagatatcag tacagctctt
     5581 cctaaccaag taatggaaat ggtcaactca gatgctttgg tgccgctaaa tgattctatc
     5641 aagcgtattg gacaagataa atttaacgaa actgccttaa atgaagcaaa aatcggagat
     5701 gattactact ctgttcctct ttattcacat gcacaagtca tgtgggttag aacagatttg
     5761 ttaaaagaac ataatattga ggttcctaaa acttgggatc aactctatga agcttctaaa
     5821 aaattgaaag aagctggagt ttatggcttg tctgttccgt ttggaacaaa tgacttaatg
     5881 gcaacacgtt tcttgaactt ctacgtacgt agtggtggag gaagcctctt aacaaaagat
     5941 cttaaagcag acttgacaag ccaacttgct caagatggta ttaaatactg ggttaaattg
     6001 tataaagaaa tctcacctca agattctttg aattttaatg tccttcaaca agctaccttg
     6061 ttctatcaag gaaaaacagc atttgacttt aactctggct tccatatcgg aggaattaat
     6121 gccaacagtc ctcaattgat tgattcgatt gatgcttatc ctattccaaa aatcaaagag
     6181 tctgataaag accaaggaat tgaaacctca aacattccaa tggttgtttg gaaaaattca
     6241 aaacatccag aagttgctaa agcattctta gaagcacttt ataatgaaga agactacgtt
     6301 aaattccttg attcaactcc agtaggtatg ttgccaacta ttaaggggat tagcgattct
     6361 gcagcctata aagaaaatga aactcgtaag aagtttaaac atgctgaaga agtaattact
     6421 gaagctgtta aaaaaggtac tgctattggt tatgaaaatg gaccaagtgt acaagctggt
     6481 atgttgacta accaacacat tattgaacaa atgttccaag atatcattac aaatggaaca
     6541 gatcctatga aagcagcaaa agaagcagaa aaacaattaa acgatttatt tgaggctgtt
     6601 cagtagatgt aaaagactag aaaataggtg ggctagtgag ctgaaaagct ctagcccaat
     6661 cttgtaaaag aagggagaag gagaatggtt aaagaacgta atttaactcg ctggatattt
     6721 gttttgccag ctatgattat cgtaggatta ctctttgttt atccgttttt ctcgagtatt
     6781 ttttatagct ttaccaataa gcatttgatt atgcctaatt ataaatttgt tggtttggct
     6841 aactataaag ctgtgctatc agatcccaac ttctttaatg cgttctttaa ttcaattaag
     6901 tggaccattt tctcattagt tggtcaagtt ttagtagggt ttgtattggc tttagctctt
     6961 cacagagtac gccacttcaa gaaattatat aggaccttat tgattgttcc ttgggcattt
     7021 cctaccatcg ttattgcctt ctcttggcag tggattctaa acggggttta tggctactta
     7081 cctaatctaa tcgtaaaatt aggtttaatg gaacatacac ctgcattttt gacagatagt
     7141 acatgggcat tcctatgttt ggtgtttatc aacatttggt ttggagcacc aatgattatg
     7201 gttaatgtgc tttcagcttt gcaaacagta ccagaagaac aatttgaggc tgctaagata
     7261 gatggtgctt caagttggca ggtgttcaag tttatcgtct ttccacatat taaagtggtt
     7321 gtaggacttc tagttgtttt gagaactgta tggatcttta ataactttga cattatctac
     7381 ctcattactg gtggtggacc agccaatgct acaacgacgc ttccaatttt tgcttataac
     7441 ctgggttggg gaactaaatt gttgggtcgt gcttcagcag ttacagtatt gctctttatc
     7501 ttcttggtgg cgatttgctt tatctacttt gctatcatca gtaagtggga aaaggagggt
     7561 agaaaataat gaagaagaaa tccagtattt atttagatat tctctcacat gtacttttag
     7621 ttggtgcgac catcgttgca gttttcccat tggtatggat tatcatatct tctgtcaaag
     7681 ggaaagggga attaactcag tatccaacac gattttggcc tgaacagttt acattagatt
     7741 atttcactca tgttatcaac gatttgcact tcattgataa cattcgaaac agtttaatca
     7801 ttgccttggc tacaaccctt attgcgatta ttatttctgc tatggcagcc tatggtattg
     7861 ttcgattctt tcctaaattg ggagcaatca tgtcgagact actcgtcatt acctacattt
     7921 tcccaccaat tttgttagca attccctatt caattgccat tgctaaagtt gggttaacaa
     7981 atagtttatt tggcttgatg atggtttatc tatcttttag tgttccatat gcagtttggc
     8041 tcttagttgg atttttccaa acagttccaa ttggaattga agaagcggct agaattgatg
     8101 gtgcaaataa atttgttacg ttttataaag ttgtgctacc gattgtagca ccaggtattg
     8161 tagcaacagc tatttataca tttatcaatg cttggaatga attcctgtat gccttgattt
     8221 tgattaacaa tacaggaaag atgacagtag cagtagccct tcgttcactt aatggttcag
     8281 aaatactaga ctggggagat atgatggcag cgtctgttat tgtagttctt ccatcaatta
     8341 ttttcttctc tatcatccaa aataggattg caagtggatt atcagaagga tctgtgaagt
     8401 agacgaaaga aggaaaaaaa tgaataaaag aggtctttat tcaaaactag gaatttctgt
     8461 tgtaggcatt agtcttttaa tgggagttcc cactttgatt catgcgaatg aattaaacta
     8521 tggtcaactg tccatatctc ctatttttca aggaggttca tatcaactga acaataagag
     8581 tatagatatc agctctttgt tattagataa attgtctgga gagagtcaga cagtagtaat
     8641 gaaatttaaa gcagataaac caaactctct tcaagctttg tttggcctat ctaatagtaa
     8701 agcaggcttt aaaaataatt acttttcaat tttcatgaga gattctggtg agataggtgt
     8761 agaaataaga gacgcccaaa agggaataaa ttatttattt tctagaccag cttcattatg
     8821 gggaaagcat aaaggacagg cagttgaaaa tacactagta tttgtatctg attctaaaga
     8881 taaaacatac acaatgtatg ttaatggaat agaagtgttc tctgaaacag ttgatacatt
     8941 tttgccaatt tcaaatataa atggtataga taaggcaaca ctaggagctg ttaatcgtga
     9001 aggcaaggaa cattacctcg caaaaggaag tattgatgaa atcagtctat ttaacaaagc
     9061 aattagtgat caggaagttt caactattcc cttgtcaaat ccatttcagt taattttcca
     9121 atcaggagat tctactcaag ctaactattt tagaataccg acactatata cattaagtag
     9181 tggaagagtt ctatcaagta ttgatgcacg ttatggtggg actcatgatt ctaaaagtaa
     9241 gattaatatt gccacttctt atagtgatga taatgggaaa acgtggagtg agccaatttt
     9301 tgctatgaag tttaatgact atgaggagca gttagtttac tggccacgag ataataaatt
     9361 aaagaatagt caaattagtg gaagtgcttc attcatagat tcatccattg ttgaagataa
     9421 aaaatctggg aaaacgatat tactagctga tgttatgcct gcgggtattg gaaataataa
     9481 tgcaaataaa gccgactcag gttttaaaga aataaatggt cattattatt taaaactaaa
     9541 gaagaatgga gataacgatt tccgttatac agttagagaa aatggtgtcg tttatgatga
     9601 aacaactaat aaacctacaa attatactat aaatgataag tatgaagttt tggagggagg
     9661 aaagtcttta acagtcgaac aatattcggt tgattttgat agtggctctt taagagaaag
     9721 gcataatgga aaacaggtcc ctatgaatgt tttctacaaa gattcgttat ttaaagtgac
     9781 tcctactaat tatatagcaa tgacaactag tcagaataga ggagagagtt gggaacaatt
     9841 taagttgttg cctccgttct taggagaaaa acataatgga acttacttat gtcccggaca
     9901 aggtttagca ttaaaatcaa gtaacagatt gatttttgca acatatacta gtggagaact
     9961 aacctatctc atttctgatg atagtggtca aacatggaag aaatcctcag cttcaattcc
    10021 gtttaaaaat gcaacagcag aagcacaaat ggttgaactg agagatggtg tgattagaac
    10081 attctttaga accactacag gtaagatagc ttatatgact agtagagatt ctggagaaac
    10141 atggtcggaa gtttcgtata ttgatggaat ccaacaaact tcatatggca cacaagtatc
    10201 tgcaattaaa tactctcaat taattgatgg aaaagaagca gtcattttga gtacaccaaa
    10261 ttctagaagt ggccgtaagg gaggtcaatt agttgtcggt ttagtcaata aagaagatga
    10321 tagtattgat tggaaatacc actatgatat tgatttgcct tcgtatggtt atgcctattc
    10381 tgcgattaca gaattgccaa atcatcacat aggtgtactg tttgaaaaat atgattcgtg
    10441 gtcgagaaat gaattgcatt taagcaatgt agttcagtat atagatttgg aaattaatga
    10501 tttaacaaaa taaaggagaa aaacatggtt aaatacggtg ttgttggagc agggtatttt
    10561 ggagctgaat tggctcgcta catgcaaaag aatgatggag cagagattac tcttctctat
    10621 gatccagata atgcagaggc gattgcagaa gaattgggag caaaagtagc aagttcctta
    10681 gatgagttgg tttctagcga tgaagtagat tgtgttatcg tcgcaactcc aaataatctt
    10741 cataaggaac cggttattaa ggctgcacag catggtaaaa atgttttctg tgaaaaacca
    10801 attgcgcttt cttatcaaga ttgtcgcgag atggtagatg cgtgtaaaga aaacaatgta
    10861 acctttatgg caggacatat tatgaatttc tttaatggtg ttcatcatgc aaaagaactc
    10921 attaatcaag gagttatcgg agacgttcta tattgtcata cagctcgtaa tggttgggaa
    10981 gaacaacaac cgtcagtatc atggaaaaaa attcgtgaaa aatcaggtgg tcacttgtat
    11041 caccacatcc atgaattgga ttgcgttcaa ttccttatgg ggggcatgcc tgaaactgta
    11101 accatgacag gtggaaatgt ggcccatgaa ggtgaacatt tcggtgatga agatgatatg
    11161 atttttgtca atatggaatt ttctaataag cgttttgcct tgttagaatg gggttcagct
    11221 tatcgttggg gtgaacatta tgtcttaatc caaggaagca aaggtgccat ccgcttagac
    11281 ttattcaact gtaaaggaac tcttaagcta gatgggcaag aaagctattt cttgattcac
    11341 gaatcgcaag aagaagatga tgatcgaact cgtatctatc atagtacaga gatggatgga
    11401 gcaattgctt atggtaaacc aggtaaacgt actccattat ggctatcatc tgtcattgat
    11461 aaagaaatgc gctatctgca tgagattatg gaaggagctc cagtatcaga agaatttgca
    11521 aaacttttga caggtgaagc tgccctagaa gcaattgcta ctgcagatgc ttgtacccag
    11581 tctatgtttg aagatcgcaa agtaaaattg tcagaaattg taaaataaat tttggtattc
    11641 tcctatttat aggtcgactt gctcctctga aagtactttt agaggagctg tttgactttg
    11701 ctagtttttg aaactgaaat ctattatact acaaactatt gaaagcgttt taattttaag
    11761 gtataataat ctcatagaaa taaagaaaag gaggaaagag gatgccacag attagcaaag
    11821 aagccttgat tgagcaaatc aaagatggaa tcatcgtttc ttgtcaggct cttcctcatg
    11881 aaccgcttta tacagaagcg ggaggggtga ttcccttgct ggtcaaagcg gctgagcaag
    11941 gtggagcagt cggtatccga gcaaacagtg ttcgcgatat caaggaaatt aaggaagtca
    12001 ctaaacttcc aatcattggg attatcaaac gtgattatcc acctcaggaa cccttcatca
    12061 cggctactat gaaagaagtt gatgaattgg cagaactgga catcgaggtg attgctctgg
    12121 attgtaccaa gcgtgaacgc tacgatggtt tggaaattca agagttcatt cgtcaggtta
    12181 aggagaaata tcctaatcag cttttgatgg ctgatactag tatcttcgaa gaagggctag
    12241 cagctgtaga agcaggaatt gactttgtcg gaacaacctt atcaggctac acatcctaca
    12301 gtccaaaagt agacggtcca gattttgaat tgattaagaa actctgtgat gccggtgtag
    12361 atgtcattgc agaaggaaaa attcatacac cagaacaagc caaacaaatc cttgaatatg
    12421 gagtgcgagg catcgttgtt ggtggcgcca ttactagacc aaaagagatt acagaacgct
    12481 tcgttgctag tcttaaataa gatgtgaggg ggagttttat gtttaaagtt ttacaaaaag
    12541 ttggaaaagc ttttatgtta cctatagcta tacttcctgc agcaggtcta cttttgggga
    12601 ttggtggtgc actttcaaac ccaaccacga tagcaactta tccaatacta gacaatagta
    12661 tttttcaatc aatattccaa gtaatgagct ctgcaggaga ggttgtattc agtaatttgt
    12721 cactacttct ctgtgtggga ttatgtattg gcttagcgaa acgagataaa ggaaccgctg
    12781 cgttagcagg agtaactggt tacttagtta tgactgcaac gatcaaagct ttggtaaaac
    12841 tttttatggc agaaggatct gcaattgata ctggagttat tggagcatta gttgtcggaa
    12901 tagttgccgt atatttgcac aaccgatata acaatattca attaccttcc gctttaggat
    12961 tctttggagg ttcacgcttc gttcctattg ttacatcgtt ctcttctatc ttgattggct
    13021 ttgtcttctt tgttatttgg ccacctttcc aacaacttct tgtttctaca ggtggatata
    13081 tttctcaggc gggtccaatt ggaacttttc tatatggatt tttaatgaga ctttctggag
    13141 cagtaggctt acatcatata atttacccta tgttttggta tactgaactt ggtggtgttg
    13201 aaactgttgc aggacaaaca gtggttggag ctcaaaaaat attttttgct caattagccg
    13261 atttggccca ttctggatta tttacagaag gaacaaggtt ttttgcaggt cgtttctcaa
    13321 caatgatgtt cggtttaccg gctgcctgtt tagcgatgta ccatagtgtt cctaaaaatc
    13381 gtcgtaaaaa atacgcgggt ttgtttttgg gagttgcttt aacatctttt attaccggta
    13441 ttacagaacc aattgaattt atgtttctat tcgtcagtcc ggttctatat gttgttcacg
    13501 cattccttga tggtgttagc ttctttattg cagacgtctt aaatatttca ataggaaaca
    13561 cattttcagg aggtgtaatc gatttcacat tatttggaat tttgcagggg aacgctaaga
    13621 cgaattgggt tcttcagatt ccatttggac ttatttggag tgttttgtat tatattattt
    13681 ttagatggtt cattactcaa ttcaacgttc taacgccagg acgaggagaa gaagtagatt
    13741 ctaaagaaat ttctgaatcc gcagattcga cttcaaatac tgcagattat ttaaaacagg
    13801 atagcctaca aattatcaga gccttgggtg gatcaaataa tatagaagat gtagatgctt
    13861 gtgtgacacg tttacgtgta gctgtaaaag aagttaatca agttgataaa gcacttttaa
    13921 aacaaattgg tgcagttgat gtcttagaag tgaagggtgg cattcaagca atctatggag
    13981 caaaagcaat cttatataaa aatagtatta atgaaatttt aggtgtagat gattaagtac
    14041 ttactgactt aataaaaaac agaggagagt gatggatgag taggatgaaa tgaaatcgca
    14101 tacaagaaat aaagaactca ttatccaagt tggatacgct tattacatag gagaatacaa
    14161 atgaaattta gaaaattagc ttgtacagta cttgcgggtg ctgcggttct tggtcttgct
    14221 gcttgtggca attctggcgg aagtaaagat gctgccaaat caggtggtga cggtgccaaa
    14281 acagaaatca cttggtgggc attcccagta tttacccaag aaaaaactgg tgacggtgtt
    14341 ggaacttatg aaaaatcaat catcgaagcg tttgaaaaag caaacccaga tataaaagtg
    14401 aaattggaaa ccatcgactt caagtcaggt cctgaaaaaa tcacaacagc catcgaagca
    14461 ggaacagctc cagacgtact ctttgatgca ccaggacgta tcatccaata cggtaaaaac
    14521 ggtaaattgg ctgagttgaa cgacctcttc acagatgaat ttgttaaaga tgtcaacaat
    14581 gaaaacatcg tacaagcaag taaagctgga gacaaggctt atatgtatcc gattagttct
    14641 gccccattct acatggcaat gaacaagaaa atgttagaag atgctggagt agcaaacctt
    14701 gtaaaagaag gttggacaac tgatgatttt gaaaaagtat tgaaagcact taaagacaag
    14761 ggttacacac caggttcatt gttcagttct ggtcaagggg gagaccaagg aacacgtgcc
    14821 tttatctcta acctttatag tggttctgta acagatgaaa aagttagcaa atatacaact
    14881 gatgatccta aattcgtcaa aggtcttgaa aaagcaacta gctggattaa agacaatttg
    14941 atcaataatg gttcacaatt tgacggtggg gcagatatcc aaaactttgc caacggtcaa
    15001 acatcttaca caatcctttg ggcaccagct caaaatggta tccaagctaa acttttagaa
    15061 gcaagtaagg tagaagtggt agaagtacca ttcccatcag acgaaggtaa gccagctctt
    15121 gaataccttg taaacggatt tgcagtattc aacaataaag acgacaagaa agtcgctgca
    15181 tctaagaaat tcatccagtt tatcgcagat gacaaagagt ggggacctaa agacgtagtt
    15241 cgtacaggtg ctttcccagt ccgtacttca tttggaaaac tttatgaaga caaacgcatg
    15301 gaaacaatca gcggctggac tcaatactac tcaccatact acaacactat tgatggattt
    15361 gctgaaatga gaacactttg gttcccaatg ttgcaatctg tatcaaatgg tgacgaaaaa
    15421 ccagcagatg ctttgaaagc cttcactgaa aaagcaaacg aaacaatcaa aaaagctatg
    15481 aaacaatagt ccttagttat tctataaaaa gtagtttttt aaagaaccta agagtgtata
    15541 cccccttttc cctctacaca gatagtgtaa gaaaaggggg cttttgttta aaatgtaaga
    15601 aactgtcacg aaattaaaat gaagttctta cataagcgaa ccataaaaaa tttcattttg
    15661 attttaaaac agttcaagaa agtcaaaaaa ttattctatt tgaaagagag gtgccgactg
    15721 tgaaagtcaa taaaatccgt atgcgggaaa cagtgatttc ctacgctttc ctagcaccag
    15781 tattattctt ctttgtcatc tttgtgttgg ctccgatggt gatgggcttc attacaagtt
    15841 tctttaacta ctcaatgact aaatttgagt ttgtaggctt ggataactat atccgtatgt
    15901 ttaaagatcc tgtctttaca aaatctctga ttaacacagt tattttggtt attggatctg
    15961 taccagttgt tgttctattc tcactctttg tagcatctca gacctatcat caaaatgtca
    16021 ttgccagatc cttctaccgt ttcgtcttct tccttcctgt tgtaacgggt agtgttgccg
    16081 tgacagttgt ttggaaatgg atttatgacc cactatcagg gattctaaac tttgtcctta
    16141 agtcaagcca catcatcagc caaaacattt cttggttggg agataaaaac tgggcattga
    16201 tggcgattat gattattctc ttgaccactt cagttggtca gcccatcatc ctttatatcg
    16261 ctgccatggg gaatattgac aattcactgg ttgaagcggc gcgtgttgat ggtgcaactg
    16321 agtttcaagt tttttggaag attaaatggc caagccttct tccaacaact ctttatattg
    16381 caatcatcac aacaattaac tcattccagt gtttcgcctt gattcagctt ttgacatctg
    16441 gtggtccaaa ctactcaaca agtaccttga tgtactacct ttacgaaaaa gccttccaat
    16501 tgacagaata cggctatgcc aacacaattg gtgtcttctt ggcagtcatg attgctatcg
    16561 taagctttgt tcaatttaaa gtacttggaa acgacgtaga atactaaaga aaggagacag
    16621 ctatgcaatc tacagaaaaa aaaccattaa cagcctttac tgttatttca acaatcattt
    16681 tgctcttgtt gactgtgctg ttcatctttc cattctactg gattttgaca ggggcattca
    16741 aatcacaacc tgatacaatt gttattcctc ctcagtggtt ccctaaaatg ccaaccatgg
    16801 aaaacttcca acaactcatg gtgcagaacc ctgccttgca atggatgtgg aactcagtat
    16861 ttatctcatt ggtaaccatg ttcttagttt gtgcaacctc atctctagca ggttatgtat
    16921 tggctaaaaa acgtttctat ggtcaacgca ttctatttgc tatctttatc gctgctatgg
    16981 cgcttccaaa acaagttgtc cttgtaccat tggtacgtat cgtcaacttc atgggaatcc
    17041 acgatactct ctgggcagtt atcttgcctt tgattggatg gccattcggt gtcttcctca
    17101 tgaaacaatt tagtgaaaat attcctacag agttgcttga atcagctaaa atcgacggtt
    17161 gtggtgagat tcgtaccttc tggagtgtag ccttcccgat tgtgaaacca gggtttgcag
    17221 cacttgcaat ctttaccttc atcaatactt ggaatgacta cttcatgcaa ttggtaatgt
    17281 tgacttcacg taacaatttg accatctcac ttggggttgc gaccatgcag gctgaaatgg
    17341 caaccaacta tggtttgatt atggcaggag ctgcccttgc tgctgttcca atcgtcacag
    17401 tcttcctagt cttccaaaaa tccttcacac agggtattac tatgggagcg gtcaaaggat
    17461 aatactctgc gaaaatcgaa tgcaaactac gtcagcttca ccttgccata cttaagtatt
    17521 gcctgtggtt agcttcctag tttgttcttc aattttcatt gagtatagga aaatcaatct
    17581 atcaagatac agaagtatat tttatagatt tagagaatat agaagttata agtgtctaca
    17641 aaatggaggg tatgcagtta ctttatgaag ttttgtcaga cacttataaa cttaagaatg
    17701 gttttagtta actatcagaa acgaaggaaa gagtatgatt tttgacgatt tgaaaaacat
    17761 caccttttac aaagggattc atcccaattt agacaaggct atcgactatc tctaccaaca
    17821 tcgtaaagat tcattcgaat taggaaagta tgagattgat ggagataaag tctttctagt
    17881 tgttcaggaa aatgtcctca atcaagttga gaataatcaa tttgaacacc ataagaacta
    17941 tgcagatttg catttgctga tagaagggca tgaatattcg agctacggtt cacgtatcaa
    18001 agaagaggca gtagcattcg acgaagcgag tgacattggc tttgttcatt gttatgaaca
    18061 ctacccactc ttattgggtt atcacaattt tgcgattttc ttcccaggtg agccacatca
    18121 gccaaatggt tatgcaggca tggaagaaaa ggttcgaaaa tatctcttta aaatcttgat
    18181 tgattaaaaa taggatgaat tgtttttttg taaagctttg ataatactct accatgaaat
    18241 tgatctttgt gaggtagaga aatgagaata aaatatttaa aaattggtat cttctaagta
    18301 tgctgcaaga gctagtttct tagatggaca ggggattaca gttgatgaga tgtcctggat
    18361 aattaggggc attgtgaatg gattgattgg tagatacata aaattaggta cttatgcagc
    18421 taagtatggt attagtatgg cgcgctcgat cttaagtagg gcagctgcaa ctgcggcagc
    18481 aagagtagga ttattgacta agatttttgg atggatttta cgaatagctg tgctcgcagc
    18541 tgatgtatat ggtaattttg ccaacaatat tgctgtagct tgggatgcac atgataaaat
    18601 ccctaacaat ggtcgtataa acttttaaaa tgcgagaatg aaagcacttt gtattttttt
    18661 attgaatatg ttagcttgga cagtgcttgc aatgataatt cgtggagggc tagatggatt
    18721 taatgagcat acttggagta ctattttaat tgcttcgctg tccgggatat atgattataa
    18781 gcccatagat aaaaatagaa aaaagtccaa aagaaaaaat agatttgttc atggtaggga
    18841 cttatgaaag ctttactgac aaaaaagaaa acagtttaca aagaaaaatg atggaggagc
    18901 aaacatggca caaaaaggag taagccttat caaggcagca tttgatacag ataactttct
    18961 catgcgtttt agtgagaagg tcttggacat cgtgacagcc aatcttcttt ttgtcgtctc
    19021 ttgtttaccc atcgtgacga ttggagtggc taaaatcagc ctctacgaga ccatgttcga
    19081 agttaagaag agcagacggg tgcctgtttt taaaatctat ctaagatctt tcaagcaaaa
    19141 tctgaaacta ggtcttcagc tgggtttaat ggagttagga attgtgtttc ttaccctttc
    19201 agatctctat cttttctggg gtcaaacagc tctgcccttc caattgctga aagccatttg
    19261 tttaggtatt ctgatttttc ttactatcgt gatgctggct agttacccta tcgcggcacg
    19321 ttatgaccta tcttggaaag aaattcttca aaaaggattg atgttggcta gttttaactt
    19381 tccttggttc ttcctcatgt tagccattct tgtcctcatt gtgatggttc tttatctgtc
    19441 cgccttcagt ctactcttag gtggctcagc cttcctactt tttgggtttg gactattggt
    19501 ctttatccag actggattga tggagaaaat tttcgcaaaa taccaatagg agctttattt
    19561 ctgaaactac tttcaaaggc tccaaacgct attctataag cgagaaacta aaatctaagt
    19621 gtctataaga tattgaaagc cttttcggta aagtgtatac taaagaagta aagaaaaatc
    19681 tgctttagca gaaaataaaa ataataggag aaaatctatg tcagatttga aaaaatacga
    19741 aggtgtcatt ccagccttct acgcatgtta tgatgagcaa ggagaagtaa gtccagagcg
    19801 tacgcgtgcc ttggttcaat acttcattga taaaggtgtt caaggtcttt atgtcaatgg
    19861 ttcttctggt gaatgtatct accaaagcgt tgaagatcgc aagttgattt tggaagaagt
    19921 catggcggta gccaaaggta aattgaccat tattgcccat gttgcctgca acaatactaa
    19981 agacagtatg gaacttgctc gccatgctga aagcttggga gtagatgcta ttgcaacgat
    20041 tccaccaatt tacttccgct tgccagaata ctcagttgcc aaatactgga acgatattag
    20101 ttctgcagct ccaaacacag actacgtgat ttacaacatt cctcaattgg caggggttgc
    20161 tttgactcca agcctttaca cagaaatgtt gaaaaatcct cgtgttatcg gtgttaagaa
    20221 ctcttctatg ccagttcaag atatccaaac ctttgtcagc cttggcgggg aagaccatat
    20281 tgtctttaac ggtccagatg aacagttcct aggtggccgc ctcatgggtg ctagggctgg
    20341 tatcggtggt acttatggtg ctatgccaga actcttcttg aaactcaatc agttgattgc
    20401 ggataaggac ctagaaacag cgcgtgaatt gcagtatgct atcaacgcaa tcattggtaa
    20461 gctcacttct gctcatggaa atatgtacgg tgtcatcaaa gaagttttga aaatcaatga
    20521 aggcttgaat attggatctg ttcgttcacc attgacacca gtgactgaag aagatcgtcc
    20581 agttgtagaa gcggctgctg ccttgattcg tgaaaccaag gagcgcttcc tctaatctaa
    20641 aaggaggtat ttatgacata ctacgttgca attgatatcg gtggaaccaa catcaagtat
    20701 ggtttggttg atcaagaggg gcaacttctt gaatcgcatg aaatgccaac tgaggcgcat
    20761 aagggtggac ctcatatctt acaaaagacc aaagatatcg tagctagtta tttagaaaaa
    20821 ggcccagtag caggtgttgc catatcttct gctgggatgg tggatccgga taagggtgag
    20881 attttctatg ctgggccgca aatccctaac tacgcaggca cccagttcaa aaaggaaatc
    20941 gaagaaagct ttactattcc ttgtgagatt gaaaatgatg tcaactgtgc aggtcttgct
    21001 gaggcagtat ctggttcagg caagggagca agtgtgacac tttgcttgac cattggaacc
    21061 ggtatcggtg gttgcttgat tatggatagg aaagtcttcc atggttttag taattcagcc
    21121 tgtgaagtcg ggtatatgca tatgcaagat ggagcttttc aggatctcgc ttctacaaca
    21181 gctttagtga aatatgtagc tgaagcccat ggagaagatg ttgatcagtg gaatggccga
    21241 cgtatcttta aggaagctac tgaaggaaac aaaatctgca tggaaggcat tgaccgtatg
    21301 gttgactatc taggaaaagg tctggcaaat atttgctacg ttgccaatcc agaagtggtt
    21361 attcttggtg gtggtatcat ggggcaagag gctatcctca aacctaagat ccgcacagcc
    21421 ttgaaagagg ctttggtacc aagtttagca gaaaaaacac gattagaatt tgcccatcac
    21481 caaaatacag cagggatgtt gggtgcatat tatcatttta agacaaaaca atcctagttt
    21541 ggctcagcca aactaggatt ttcttacacg tttttgtcta cgatagccgt tgagtttttt
    21601 attttcccag tagctattaa agattttttc cttgctttcg cgattgattt ccaaaaagta
    21661 ggcataaatc aaatcgataa agaagagcat aggaagttga gcggatattc gttggatata
    21721 ggagggttgg ctgtgggtgg ctacaagaac agtctctgta taggtctggc tatctttatt
    21781 gggaacactt gtaaagagta cagtctttgc ccccatctcc ttggcatcta atagactatc
    21841 taaaatagaa ggagttgagc ctgaaagtga gaagcccagt actagacaat tttcatccat
    21901 gatgctggtt gtccaggcaa agccgtcttg gtctgtcaaa gcttcgcaga ccacacctag
    21961 tcgcataaaa cgtaatttca tttcacgggc gacgaggcca gaactccctg ttccaaagaa
    22021 gtagatacgc tcagcatctt cgattagctg ggcaattcgc tctagttgga tttcgtcaat
    22081 caagtcttgt gtttgttccc tcatattgct ataacttctg aggactcgtt tggtcagtgg
    22141 actgtgcttg gagacttggt tggcttgatt ttctgcctga tgttggtatt ggaaaataaa
    22201 ttctcggtag ccagtaaagc cacacttttt agcaaagcgg gtcaaagcag cttgagaaat
    22261 atgtaatttt tgggtgactt gttgagaaga taaatcatct gtaatcgttt cagcttgcaa
    22321 aaaatagcga gcgatttctt gctctaggtc tgtcatttct tcaaaatgtg aatcaatgat
    22381 agttgcgata tctggtttgt ccatagggaa agctccttta catgagtcat actggaagac
    22441 tagatcaggg aatagtcaca cttcattata acacataata taaggataga taaataaaaa
    22501 cgcatctctg ttttaaaaac gaaaaaatcg aaaaagcttc tctcttttcc ataattttct
    22561 actcaaattg tggtacaatt aagagtaaga ttttaagtta gaaatgagac tgatttgtat
    22621 gagaaaattt aacagccatt cgattccgat tcggcttaat ttattgtttt caatcgtcat
    22681 tttactcttt atgaccatta ttggtcgttt gttgtatatg caggttttga acaaggattt
    22741 ttacgaaaaa aagctagcct cagctagtca gaccaagatt acaagcagtt cagcccgtgg
    22801 ggaaatttat gatgctagtg gaaaaccttt ggtagaaaat acgttaaagc aggttgtttc
    22861 ctttacgcgt agcaataaaa tgacggctac agacttaaaa gaaacagcta aaaagttact
    22921 gacttatgtg agcatcagtt ctccaaattt gacagaacgc cagctggcgg attactattt
    22981 ggctgatcct gaaatctata aaaaaacagt ggaagctctc ccaagcgaga aacgcttgga
    23041 ttcagatggc aatcgtctat ccgaatcaga actgtataac aatgcggtcg atagtgtaca
    23101 aacgagtcaa ctaaactata cagaggatga aaagaaagaa atctatcttt ttagtcagtt
    23161 aaatgctgtt ggaaactttg cgacaggaac cattgcgaca gatcctctaa atgattctca
    23221 ggtggctgtt attgcctcta tttcaaagga gatgcctggc attagtattt ctacttcttg
    23281 ggatagaaag gttttggaaa cttccctttc ttctatagtt gggagtgtat ccagtgaaaa
    23341 agctggtctc ccagcggaag aagcagaagc ctatcttaaa aaaggctatt ctctaaatga
    23401 tcgtgtagga acctcctatt tggaaaagca atatgaagag accttacaag gaaaacgctc
    23461 ggtaaaagaa atccatctgg ataaatatgg caatatggaa agcgtggata caattgagga
    23521 aggtagtaag ggaaacaata tcaaactgac cattgatttg gctttccaag atagcgtgga
    23581 tgctttactg aaaagttatt tcaattccga gctagaaaat ggtggagcca agtattctga
    23641 aggtgtctat gcagtcgccc ttaacccaaa aacaggtgcg gttttgtcta tgtcagggat
    23701 taaacatgac ttgaaaacgg gagagttgac gcctgattcc ttgggaacgg taaccaatgt
    23761 ctttgttcca ggttcggttg tcaaggcggc gaccatcagt tcaggttggg aaaatggagt
    23821 cttgtcagga aaccagacct tgacagacca gtccattgtc ttccaaggtt cagctcccat
    23881 caattcttgg tatactcagg cttacggttc attccctatc acagcggtcc aagctctgga
    23941 gtattcatca aatacctata tggtccaaac agccttaggt cttatggggc aaacctatca
    24001 acccaatatg tttgtcggca ccagcaatct agagtctgct atggagaaac tgcgttcaac
    24061 ctttggcgaa tatggcttgg gtactgcgac aggaattgac ctaccagatg aatctactgg
    24121 atttgttccc aaagagtata gctttgctaa ttacattact aatgcctttg ggcagtttga
    24181 taactatacg ccgatgcagt tggctcagta tgtagcaact attgcaaatg atggtgttcg
    24241 tgtggctcct cgtattgttg aaggcattta tggtaataat gataagggag gactgggtga
    24301 cttgattcag caactgcaac cgacagagat gaataaggtc aatatatccg actccgatat
    24361 gagcatcttg caccaaggtt tttatcaggt tgcccatggt actagtgaat tgacaactgg
    24421 acgtgccttt tcaaatggtg ccttggtatc cattagcgga aaaacaggta cagccgaaag
    24481 ctatgtggca gatggtcagc aagcaaccaa taccaatgcg gtggcctatg ccccatctga
    24541 taatccccaa atcgctgtcg cagtggtctt tcctcataat accaatctaa caaatggtgt
    24601 aggaccttcc attgcgcgtg acattatcaa tctgtatcaa aaataccatc caatgaacta
    24661 gaaaggaaat tatgctttat ccaacaccta ttgccaagtt gattgacagt tattctaagt
    24721 taccgggtat cgggattaag acggctacgc gtctggcctt ttatacgatt gggatgtctg
    24781 ctgatgatgt caatgaattt gcaaaaaatc tcctttctgc taagagagaa ttgacatatt
    24841 gttctatttg tggacgtttg acagacgacg atccttgttc tatctgtact gatccgactc
    24901 gtgaccagac aacaatttta gttcttgagg atagtagaga tgtggcagcc atggaaaata
    24961 tccaagaata ccatggactc tatcatgtcc ttcatggcct catttctcct atgaatggta
    25021 tcagtccgga cgatatcaat ctcaagagcc ttatgactcg tcttatggat agtgaggttt
    25081 cagaagtgat tgtggcgact aatgctacag cggatggtga agcgacttcc atgtatcttt
    25141 cacgtttgct caagccggct ggtatcaagg ttacgcgtct agcacgaggt ctcgctgtgg
    25201 gagcggacat tgagtatgcg gacgaagtga cactcttacg agccattgaa aatcggacag
    25261 agttgtaagt gtaggcaaat ttacgaactc cattcattta taaaaaatca aagaggctga
    25321 aaatcgttcc tatcggcctc tttttgtata gtgtgatgag taggctcagg ttcaagtttt
    25381 aaaaaaccaa gcaaatatga tatactaaag agcgagtatt ctagtagaat taggacaaat
    25441 aatatgaaac aaacgattat tcttttatat ggtggacgga gtgcggaacg cgaagtctct
    25501 gtcctttcag ctgagagtgt catgcgtgcg gtcaattacg accgtttcac agtcaagact
    25561 ttctttatca gtcagtcagg tgactttatc aaaacgcagg aatttagtca tgctccgggg
    25621 caagaagacc gtctcatgac caatgaaacc attgattggg ataagaaagt tgcaccaagt
    25681 gctatctacg aagaaggtgc agtggtcttt ccagtccttc acgggccaat gggagaagat
    25741 ggctctgttc aaggattctt ggaagttttg aaaatgcctt acgttggttg caacattttg
    25801 tcatcaagtc ttgccatgga taaaatcacg actaagcgtg ttctggaatc tgctggtatt
    25861 gcccaagttc cttatgtggc tatcgttgaa ggcgatgatg tgactgctaa aatcgctgaa
    25921 gtggaagaaa aattggttta tccagtcttc actaagccgt caaacatggg gtctagtgtc
    25981 ggtatttcta agtctgaaaa ccaagaagaa ctccgtcaag ccttaaaact tgccttccga
    26041 tatgacagcc gtgtcttggt tgagcaagga gtgaatgccc gtgaaattga ggttggcctc
    26101 ttgggtaact acgatgtcaa gagcacgcta ccaggagaag ttgtcaagga cgttgccttt
    26161 tatgactacg atgccaagta tattgataac aagattacta tggatattcc tgccaaaatc
    26221 agtgatgatg tggtggctgt catgcgtcaa aatgcagaaa cagccttccg tgccattggt
    26281 ggccttggtc tatctcgttg cgatttcttc tatacagata agggagagat ttttctcaac
    26341 gagctcaata ccatgccagg tttcacccag tggtctatgt acccactact ttgggacaat
    26401 atggggatca gctacccaaa actaatcgag cgtttggttg accttgccaa ggaaagtttt
    26461 gacaagcgcg aagcgcattt gatataaaat gaaagagagg gtagaagcca gaaccatcac
    26521 tgcaaggtga ctagagttct cggacttcag ccctttttaa aggagtagaa atgaaattaa
    26581 caatccatga aattgcccaa gttgttggag ccaaaaatga tatcagtatc tttgaggaca
    26641 cccagttaga aaaagctgag tttgatagtc gtttgattgg aactggagat ttatttgtgc
    26701 cacttaaagg tgcgcgtgat ggccatgact ttattgaaac agcctttgaa aatggtgcag
    26761 cagtaacctt gtctgagaaa gaggtctcaa atcatcctta cattctagta gatgatgttt
    26821 tgacatcctt tcaatcccta gcatcctact atcttgaaaa aacgactgtt gatgtctttg
    26881 ctgttacagg ttcaaatggc aagacaacga ctaaggatat gttggcgcat ttactgtcaa
    26941 caagatacaa gacctacaaa acacaaggca attacaataa tgagattggc cttccttaca
    27001 cagttcttca tatgcctgaa ggaacagaaa agttggtttt ggagatggga caggatcact
    27061 tgggcgatat tcatctcttg tctgaattgg ctcgtccaaa aacagccatc gtgaccttgg
    27121 ttggagaagc ccatttggcc tttttcaaag accgttcaga gattgctaag ggaaaaatgc
    27181 aaattgcaga cggaatggct tcaggttcct tgcttttagc gccggctgac cctatcgtag
    27241 aggactattt gccaactgat aaaaaggtgg tccgttttgg gcaaggggca gagttggaaa
    27301 tcacagactt ggttgagcgt aaggacagtc tgacctttaa ggccaatttc ttagagcaag
    27361 cccttgattt gccagtaact ggtaagtaca atgctaccaa tgctatgatt gcgtcctatg
    27421 ttgccctaca agaaggagtt tcagaggagc aaattcatca ggccttccaa ggtcttgaat
    27481 tgacgcgtaa tcgtactgag tggaagaaag cagccaatgg agcagatatc ctgtcagacg
    27541 tatataatgc caatccaact gctatgaagc tgattttaga gactttctct gccattccag
    27601 ccaatgaagg tggcaagaaa attgcagtgt tggcggatat gaaggagctt ggtgaccagt
    27661 ctattcaact ccataaccag atgattttga gcctttctcc agatgtgctt gataccgtta
    27721 ttttctatgg agaagacatt gctgaattag cccaattggc cagtcaaatg ttcccaattg
    27781 gccacgttta ctacttcaag aaaacagaag accaagacca atttgaagac ctagttaagc
    27841 aggtcaaaga aagccttggg gctcatgacc aaatcctgct caaaggctct aactctatga
    27901 atctagccaa gttggtagaa agtttagaaa atgaagacaa gtgattttgt caagtatttg
    27961 caaagaatga ttgccattac agatactgga ttaaccttta caaaagatcc gtttgaccgt
    28021 gagcgctacg aagacttgcg agaccttcta tctgaaatgt tgaatcaagc atcagacctt
    28081 gattccgaag aagtggcaga agtcttgaag ccaacttctg cttatgcgac tcccttaatg
    28141 gacgtccgtg cttggattgt tgaggacgaa aagatttgtc tggttagggg acaaggagag
    28201 gatagttggg ctttgccagg tggctttggt gaagtcggct attctccaac tgaaaatatt
    28261 ctcaaggaaa ttgaagaaga aaccggtttt aaagccaaag ttgaaagact gctagctgtt
    28321 tttgatacca atcgtttcca actacagagc aaacaatatg caaagtttgt ttttgaatgt
    28381 aagcttctcg atggacaatt ccaagaaaat caagaaatcg ctgaccttca attttttgca
    28441 attgacccac tgccgaattt atctgaaaaa cgcattacca aggagcaaat cgagattctt
    28501 tggcaggttt atcaaggtca gagggagcaa tatcttgact aagaagatga ttatcgtatt
    28561 tctaaatcca tttttgacaa ctagcatggt ataataatat gcaggaaaat tttgaattat
    28621 gaggaagact agatgaattt atgggatatt ttctttacga ctcaggcaac cgagccgccc
    28681 aaatttgacc ttttttggta tgttagccta tttacgctct tagccttaac cttttataca
    28741 gcccatcgct atcgtgaaaa gaaggtttac caacgatttt tccaaatctt gcagactgtt
    28801 cagttaatcc ttctttatgg ttggtactgg gttaatcata tgccactgtc agaaagccta
    28861 cccttttacc attgccgtat ggctatgttt gtggtactct tgcttcctgg tcagtccaaa
    28921 tataaacaat actttgcatt attgggaaca tttgggacat tagcagcctt tgtttatcca
    28981 gtgccagatg cttacccttt tccacatatc accattctat cctttatctt tggtcattta
    29041 gcactcttgg ggaactctct agtttatcta ttgagacagt ataatgcgcg attgctggat
    29101 gtgaagggaa tttttctcat gacctttgcc ctaaatgcct tgatttttgt ggtcaatttg
    29161 gtgacaggtg gcgattacgg atttttgaca aaaccgccat tggttgggga tcacggtcta
    29221 gtagctaatt atttacttgt ttcaattgtg ctggtagcta ctatcagttt gactaagaaa
    29281 atcttagaat tctttttagc tcaagaagca gaaaaaatga ttgcaaagga agcttaacac
    29341 agagctttct tttttgctct tagagagttt ttacaagcag cttataaaat aagaatttct
    29401 gaatagacaa actcaaaaaa tggctgggaa atttaggaaa aaagcaagca cgattaaatt
    29461 ttttgtgtta taatattttg tgaatagcta tgcctatgtt tagctatgga ataatacgaa
    29521 gtgcgaaact tggaagatag agaggaagcg atgtaatggc tagagaaggc ttttttacag
    29581 gtctagatat tggaacaagc tctgtcaagg tgcttgtggc cgagcagaga aatggtgaat
    29641 taaatgtaat tggcgtgagt aatgccaaaa gtaaaggtgt aaaggatgga attattgttg
    29701 atattgatgc agcagcaact gctatcaagt cagccatttc ccaagcggaa gaaaaggcag
    29761 gcatttcgat taaatcagtg aatgtcggct tgcctggtaa tcttttgcag gtagaaccaa
    29821 ctcaggggat gattccagta acatctgata ctaaggaaat tacggatcaa gatgttgaaa
    29881 atgttgtcaa atcagctttg acaaagagta tgacacctga ccgtgaagtc attaccttta
    29941 ttcctgaaga atttattgtg gatggtttcc aagggattcg tgacccacgt ggcatgatgg
    30001 gggttcgcct tgaaatgcgt ggtttgcttt atacaggacc tcgtactatc ttgcacaatt
    30061 tgcgtaagac ggttgagcgt gcaggtgttc aggttgaaaa tgttatcatt tcaccactag
    30121 caatggttca gtctgttttg aacgaagggg aacgtgaatt tggtgctaca gtgattgata
    30181 tgggggcagg tcaaacgact gtcgctacaa tccgtaatca agaactccag ttcacacata
    30241 ttctccaaga aggtggagat tatgtaacta aagatatctc caaggttttg aaaacctctc
    30301 gcaaattagc ggaaggctta aaactgaatt acggggaagc ctatccgcct cttgcaagca
    30361 aagaaacctt ccaagtagag gttattggag aagtagaagc agtcgaagtg acggaagcct
    30421 acttgtcaga aattatttct gcacgaatca agcacatcct tgaacaaatc aagcaagaat
    30481 tagatagaag gcgtctattg gacctccctg gtggtattgt cttaatcggt gggaatgcca
    30541 ttttaccagg tatggttgag cttgctcagg aagtctttgg cgtccgtgtc aagctttatg
    30601 ttccaaatca agttggtatc cgtaatccag cctttgcgca tgtgattagt ttatcagaat
    30661 ttgcgggtca attaacagaa gttaatcttt tggctcaagg agcgataaaa ggtgagaatg
    30721 acttaagtca tcagccaatt agttttggtg ggatgctgca aaaaacagct cagtttgtac
    30781 aatcaacgcc tgttcaacca gctcctgctc cagaagtaga gccggtggcg cctacagaac
    30841 caatggcgga tttccaacaa gcttcacaaa ataaaccgaa attagcagat cgtttccgtg
    30901 gcttgatcgg aagcatgttt gacgaataaa gaggaaaaat aaattatgac attttcattt
    30961 gatacagctg ctgctcaagg ggcagtgatt aaagtaattg gtgtcggtgg aggtggtggc
    31021 aatgccatca accgtatggt cgacgaaggt gttacaggcg tagaatttat cgcagcaaac
    31081 acagatgtac aagcattgag tagtacaaaa gctgagactg ttattcagtt gggacctaaa
    31141 ttgactcgtg gtttgggtgc aggaggtcaa cctgaggttg gtcgtaaagc cgctgaagaa
    31201 agcgaagaaa cattgacgga agctattagt ggtgccgata tggtcttcat cactgctggt
    31261 atgggaggag gctctggaac tggagctgct cctgttattg ctcgtatcgc caaagattta
    31321 ggtgcgctta cagttggtgt tgtaacacgt ccctttggtt ttgaaggaag taagcgtgga
    31381 caatttgctg tagaaggaat caatcaactt cgtgagcatg tagacactct attgattatc
    31441 tcaaacaaca atttgcttga aattgttgat aagaaaacac cgcttttgga ggctcttagc
    31501 gaagcggata acgttcttcg tcaaggtgtt caagggatta ccgatttgat taccaatcca
    31561 ggattgatta accttgactt tgccgatgtg aaaacggtaa tggcaaacaa agggaatgct
    31621 cttatgggta ttggtatcgg tagtggagaa gaacgtgtgg tagaagcggc acgtaaggca
    31681 atctattcac cacttcttga aacaactatt gacggtgctg aggatgttat cgtcaacgtt
    31741 actggtggtc ttgacttaac cttgattgag gcagaagagg cttcacaaat tgtgaaccag
    31801 gcagcaggtc aaggagtgaa catctggctc ggtacttcaa ttgatgaaag tatgcgtgat
    31861 gaaattcgtg taacagttgt tgcaacgggt gttcgtcaag accgcgtaga aaaggttgtg
    31921 gctccacaag ctagatctgc tactaactac cgtgagacag tgaaaccagc tcattcacat
    31981 ggctttgatc gtcattttga tatggcagaa acagttgaat tgccaaaaca aaatccacgt
    32041 cgtttggaac caactcaggc atctgctttt ggtgattggg atcttcgccg tgaatcgatt
    32101 gttcgtacaa cagattcagt cgtttctcca gtcgagcgct ttgaagcccc aatttcacaa
    32161 gatgaagatg aattggatac acctccattt ttcaaaaatc gttaagtaaa tgaatgtaaa
    32221 agaaaataca gaacttgttt ttcgagaagt tggagaggct agtctgagtg ctcatcgaga
    32281 gagtggttcg gtctctgtca ttgcagttac caagtatgta gatgtaccga cagcggaagc
    32341 cttgctttcg ctaggtgttc atcatatcgg tgaaaatcgt gtagataagt ttctggaaaa
    32401 atatgaagct ttaaaagatc gagatgtgac ttggcatttg attggtacct tgcaaagacg
    32461 taaggtgaaa gatgtcattc aatacgttga ttatttccat gcattggact cagtaaagct
    32521 agcaggggaa attcaaaaaa gaagtgaccg agtcatcaag tgtttccttc aagtaaatat
    32581 ttctaaagaa gaaagcaaac acggtttttc gagagaggaa ctgctggaaa tcttgccaga
    32641 gttagccaga ctagataaga ttgaatatgt tggtttaatg acgatggcac cttttgaggc
    32701 tagcagtgag cagttgaaag agattttcaa ggcgacccaa gatttacaaa gagaaattca
    32761 agagaaacaa attccaaata tgcctatgac cgagttaagt atgggaatga gtcgtgatta
    32821 taaagaagcg attcaattcg gttccacttt tgttcgtata ggtacatcat tttttaagta
    32881 ggagagaacc atgtctttaa aagatagatt cgatagattt atagattatt ttacggagga
    32941 tgaggattca agtctccctt atgaaaaaag agatgagcct gtgtttactc cagtaaattc
    33001 ttcacaggaa ccggctctcc caatgaatca accttcacag tcggctggta caaaagagaa
    33061 caatatcacc agacttcatg caagacaaca ggaattggca aatcagagtc agcgtgcaac
    33121 ggataaggtc attatagatg ttcgttatcc tagaaaatat gaggatgcaa cagaaattgt
    33181 tgatttattg gcaggaaacg aaagtatctt gattgatttt cagtatatga cagaggtgca
    33241 ggctcgtcgt tgtttggact atttggatgg agcttgtcat gttttagctg gaaatttgaa
    33301 aaaggtagct tctaccatgt atttgttgac accagtgaat gttattgtaa atgttgaaga
    33361 tatccgttta ccagatgaag atcaacaggg tgagttcggt tttgatatga agcgaaatag
    33421 agtacgataa tgattttttt aattcgtatg atttataatg cagtggatat ttactccctg
    33481 attttggtag ccttcgctgt catgtcttgg tttccaggtg cctacgaatc cagtttaggt
    33541 cgttggattg tagcgttggt gaaaccagtg cttgctccct tgcaacgcct gcctttacag
    33601 atagcgggtc ttgatttatc tgtttgggtt gcgattgttt tggttcgatt tttaggagaa
    33661 aacctagtgc gttttctggc gatgatagga tgaataaagg gatttatcag catttctcca
    33721 tagaagatcg tccatttctt gacaagggaa tggaatggat aaagaaggta gaagatagct
    33781 atgctccttt tttaactcct tttatcaatc ctcatcagga gaagctatta aagattttgg
    33841 ccaaaaccta tggtcttgct tgtagcagta gtggggaatt cgtatcgagt gagtatgttc
    33901 gagttttatt atacccagat tatttccaac cagagttttc agattttgaa atatctctcc
    33961 aggaaattgt gtattccaat aaatttgaat atttaacgca tgctaagatt ttagggacag
    34021 tcatcaatca attagggatt gaacggaaac tttttggaga tatcctagta gatgaagaac
    34081 gggcgcagat tatgattaat cagcagtttc ttcttctctt tcaagatgga ctaaagaaaa
    34141 ttggtcgtat acctgtttcg ctggaggaac gtcctttcac cgagaaaata gataagctag
    34201 aacagtatcg agaactggat ttatctgtgt ctagttttcg attagatgtt cttttatcaa
    34261 atgttttgaa actatctagg aatcaagcaa accagttgat tgaaaagaaa cttgtccaag
    34321 taaattatca tgtggtagac aaatcagatt acactgttca agttggagac ttgattagtg
    34381 tgagaaaatt tggtcgcttg agattacttc aagataaggg acaaacgaaa aaagagaaga
    34441 aaaaaataac cgtccagtta ttattaagta agtgaggaat agaatgccaa ttacatcatt
    34501 agaaataaag gacaagactt ttggaactcg attcagaggt tttgatccag aagaagtcga
    34561 tgaattttta gatattgtgg ttcgtgatta cgaagatctt gtgcgtgcga atcatgataa
    34621 aaatttgcgt attaagagtt tagaagagcg tttgtcttac tttgatgaaa taaaagattc
    34681 attgagccag tctgtattga ttgctcagga tacagctgag agagtgaaac aggcggcgca
    34741 tgaacgttca aacaatatca ttcatcaagc agagcaagat gcgcaacgct tgttggaaga
    34801 agctaaatat aaggcaaacg agattcttcg tcaagcaact gataatgcta agaaagtcgc
    34861 tgttgaaaca gaagaattga agaacaagag ccgtgtcttc caccaacgtc tcaaatctac
    34921 aattgagagt cagttggcta ttgttgaatc ttcagattgg gaagatattc tccgtccaac
    34981 agctacttat cttcaaacca gtgatgaagc ctttaaagaa gtggttagcg aagtacttgg
    35041 agaaccgatt ccagctccaa ttgaagaaga accaattgat atgacacgtc agttctctca
    35101 agcagaaatg gaagaattac aagctcgtat tgaggtagcc gataaagaat tgtctgaatt
    35161 tgaagctcag attaaacagg aagtggaaac tccaactcct gtagtgagtc ctcaagttga
    35221 agaagagcct ctgctcatcc agttggccca atgtatgaag aaccagaagt agctccagtg
    35281 catccgacag gtccaacacc agctacagaa actgttgatt cagcaccggg atttgaagca
    35341 ccgcaagaat ctgttacaat tttataagaa atattctgag aacaatatct tatccttata
    35401 ttcccagcga gcaggagatg gtgtgagtcc tgcattccct atcgataaga ttatcctctc
    35461 aaaaactcaa gtctgaatct agtaagattt gacgttcccc acgttacggg ataagaggga
    35521 gaaagactaa aactttttcc gaataaaggt ggtaccacga ttttcgtcct ttttggaagt
    35581 cgtggttttt aatttgttat tatttataaa ggagatacca tgaaactcaa agacaccctt
    35641 aatcttggga aaactgaatt cccaatgcgt gcaggccttc ctaccaaaga gccagtttgg
    35701 caaaaggaat gggaagatgc aaaactttat caacgtcgtc aagaattgaa ccaaggaaaa
    35761 cctcatttca ccttgcatga tggccctcca tacgctaacg gaaatatcca cgttggacat
    35821 gctatgaaca agatttcaaa agatatcatt gttcgttcta agtctatgtc aggattttac
    35881 gcaccattta ttcctggttg ggatactcat ggtctgccaa tcgagcaagt cttgtcaaaa
    35941 caaggtgtca aacgtaaaga aatggacttg gttgagtact tgaaactttg ccgtgagtac
    36001 gctctttctc aagtagataa acaacgtgaa gattttaaac gtttgggtgt ttctggtgac
    36061 tgggaaaatc catatgtgac cttgactcct gactatgaag cagctcaaat tcgtgtattt
    36121 ggtgagatgg ctaataaggg ttatatctac cgtggtgcta agccagttta ctggtcatgg
    36181 tcatctgagt cagcacttgc tgaagcagag attgaatacc atgacttggt ttcaacttcc
    36241 ctttactatg ccaacaaggt aaaagatggc aaaggagttc tagatacaga tacttatatc
    36301 gttgtctgga caacgactcc atttaccatc acagcttctc gtggtttgac ggttggtgca
    36361 gatattgatt acgttttggt tcaacctgct ggtgaagctc gtaagtttgt cgttgctgct
    36421 gaattattga ctagcttgtc tgagaaattt ggctgggctg atgttcaagt tttggaaact
    36481 taccgtggcc aagaactcaa ccacatcgta acagaacacc catgggatac agctgtagaa
    36541 gagttggtaa ttcttggtga ccacgttacg actgactctg gtacaggtat tgtccataca
    36601 gcccctggtt ttggtgagga cgattacaat gttggtattg ctaataatct tgaagtcgca
    36661 gtgactgttg atgaacgtgg tatcatgatg aagaatgctg gtcctgaatt tgaaggtcaa
    36721 ttctatgaaa aggtagttcc aactgttatt gaaaaacttg gtaacctcct tcttgcccaa
    36781 gaagaaatct ctcactcata tccatttgac tggcgtacta agaaaccaat catctggcgt
    36841 gcagttccac aatggtttgc ctcagtttct aaattccgtc aagaaatctt ggacgaaatt
    36901 gaaaaagtga aattccactc agaatggggt aaagtccgtc tttacaatat gatccgtgac
    36961 cgtggtgact gggttatctc tcgtcaacgt gcttggggtg ttccacttcc tatcttctac
    37021 gctgaagatg gtacagctat catggtagct gaaactattg aacacgtagc tcaacttttt
    37081 gaagaacatg gttcaagcat ttggtgggaa cgtgatgcca aagacctctt gccagaagga
    37141 tttactcatc caggttcacc aaacggcgag ttcaaaaaag aaactgatat catggacgtt
    37201 tggtttgact caggttcatc atggaatgga gtggtggtaa accgtcctga attgatttac
    37261 ccagccgacc tttacctaga aggttctgac caataccgtg gttggtttaa ctcatcactt
    37321 atcacatctg ttgccaacca tggcgtagca ccttacaaac aaatcttgtc acaaggtttt
    37381 gcccttgatg gtaaaggtga gaagatgtct aaatctcttg gaaataccat tgctccaagc
    37441 gatgttgaaa aacaattcgg tgctgaaatc ttgcgtctct gggtaacaag tgttgactca
    37501 agcaatgacg tgcgtatctc tatggatatt ttgagccaag tttctgaaac ttaccgtaag
    37561 attcgtaaca ctcttcgttt cttgattgcc aatacatctg actttaaccc agctcaagat
    37621 acagtcgctt acgatgagct tcgttcagtt gataagtaca tgacgattcg ctttaaccag
    37681 cttgtcaaga ccattcgtga tgcctatgca gactttgaat tcttgacgat ctacaaggcc
    37741 ttggtgaact ttatcaacgt tgacttgtca gccttctacc ttgattttgc caaagatgtt
    37801 gtttacattg aaggtgccaa atcactggaa cgccgtcaaa tgcagactgt cttctatgac
    37861 attcttgtca aaatcaccaa actcttgaca ccaatccttc ctcacactgc ggaagaaatt
    37921 tggtcatatc ttgagtttga aacagaagac ttcgtccaat tgtcagagtt accagaggct
    37981 caaacttttg ctaatcaaga agaaatcttg gatacatggg cagccttcat ggacttccgt
    38041 ggacaagcac aaaaagcctt ggaagaagct cgtaatgcaa aagttatcgg taaatcactt
    38101 gaagcacact tgacagttta tccaaatgaa gttgtgaaaa ctctactcga agcagtaaac
    38161 agcaatgtag ctcaactttt gatcgtgtct gagttgacca tcgtagaagg accagctccg
    38221 gaagctgccc ttagcttcga agatgtagcc ttcacagttg aacgtgctac tggtgaagta
    38281 tgtgaccgtt gccgtcgtat cgacccaaca acagcagaac gcagctacca ggcagttatc
    38341 tgtgaccact gtgcaagcat cgtagaagaa aactttgcgg aagcagtcgc agaaggattt
    38401 gaagagaaat aagattgaaa agtctaggca aaattcaatt tgagaagaaa agacaactaa
    38461 ttttatagtc tattaaacgc attgtatcac gtttttgaat acctgatatg atgcgttttt
    38521 tatttatttt aaaaatttgc gaggtatgac tttttatact caacaagaat caaagagaaa
    38581 cttagcaatc taacagtagt aagataaaat aggaatttga tattagggat aagattggta
    38641 aatagtgtaa tatttttaca acaataaatt tatatagtta tttctggttt ctgaaaagta
    38701 ttatatttta tttcatatta tacaaatttt tattttataa tatcagaaca tacttttttt
    38761 aaaagcaaat atgatacaat tttatttgaa aaaaataaaa aaggagattt tattataaaa
    38821 ttaaaaagac ttgctttaat tagtggtatc gtcggtcttg tgggaggaat tttacttctt
    38881 attggtcctt ttgtcttgtt gggaacagcg gtaaacacag ctgctacaac tcttaatgga
    38941 ggagctactg caggggcttt ttcaggtgta gccttactct tgaatgcctt gaagattgca
    39001 aatcttgttc ttggtatcat tgctattgtt tactataaag gagataagcg tgtaggtgca
    39061 gctccgtctg tactaatgat tgtttctggt ggagttagtc tcattccatt cttaggatgg
    39121 gttgggggga ttcttgctat tatcggagga tctctattcc ttgcaacatt gaagaaattc
    39181 aaatcagaag aataaaaggt attttagcat gaaaagaaca aaaagtttat cggtatagga
    39241 gtagctctat tatctctttc tcttctagtt gcatgtggaa cataaagttc aaagaatact
    39301 tcaacaagta atgatgagaa gacagtagca acatccaata gttcaaaaga aacaatcact
    39361 ttcgatacac cggttgtaac agacgatgcg attgaatcaa tacgcactta tgcagattat
    39421 atagatcttt ataaaaatat ttttgatgat tattttacta aagctgagga aggtttcaaa
    39481 ggcacagcta tggaaaataa tgactcgttt actaaactaa aagagtcaac tcaaaaatta
    39541 ttcgatgcgc agaaaaaaag gttaaataat gaagatagaa tagaaacaac caaaaacaat
    39601 gtgattgcca aacattgtca aacagtcctt tcctttttgg ttttgactag cttttttgtg
    39661 aaaaattgtg taaaatagaa tagataaacg aggggaaacc tcggaaaatt taaaggagaa
    39721 tccatctaat ggtaaaattg gtttttgctc gccacggtga gtctgaatgg aacaaagcta
    39781 accttttcac tggttgggct gatgttgatt tgtctgaaaa aggtacacaa caagcgattg
    39841 acgctggtaa attgatcaaa gaagctggta tcaaatttga ccaagcttac acttcagtat
    39901 tgaaacgtgc tatcaaaaca actaacttgg ctcttgaagc ttctgaccaa ttgtgggttc
    39961 cagttgaaaa atcatggcgc ttgaacgaac gtcactatgg tggtttgact ggtaaaaata
    40021 aagctgaagc tgctgaacaa tttggtgatg agcaagttca catctggcgt cgttcatacg
    40081 atgtattgcc tccaaatatg gaccgtgatg atgagcactc agctcacaca gaccgtcgtt
    40141 atgcttcact tgacgactca gtaatcccag atgctgaaaa cttgaaagtg actttggaac
    40201 gtgctcttcc attctgggaa gataaaatcg ctccagctct taaagatggt aaaaacgtat
    40261 tcataggagc tcacggtaac tcaatccgtg cccttgtaaa acacatcaaa ggtttgtcag
    40321 atgacgagat catggacgtg gaaatcccta acttcccacc attggtattc gaattcgacg
    40381 aaaaattgaa cgtcgtttct gaatactacc ttggaaaata aaaaattgta agcctaggat
    40441 tgatttctag gctttttatg ttagtatgga agtatgataa ggaataaaaa acaagattat
    40501 gtactggcct acaagcaacc agcttcaacc acttacatgg gttgggaaga agaagcttta
    40561 ccgataggca atggttcttt aggagcaaaa gtatttggcc ttataggggc tgaacggatt
    40621 caatttaatg aaaaaagtct ctggtctgga ggtccacttc ctgatagttc agattatcag
    40681 ggtggaaatc ttcaggatca gtatggtttt ttagctgaga ttcggcaggc tttggagaag
    40741 agagattaca atctggctaa ggaactggct gagcagcacc taattgggcc aaaaacgagt
    40801 caatatggga cctatctgtc ttttggggat attcacattg agttcagcca gcaaggtacg
    40861 actttgtctc aggtgacgga ctatcagaga cagctgaata ttagtaaggc acttgcgacg
    40921 acttcttatg tctataaggg aacgcaattt gaacgtgaag cttttgcgag ttttccagat
    40981 gatctcttgg ttcaatgttt tactaaggaa gggttggaaa ctctagattt tactatagaa
    41041 ctatccttga cctgtgattt ggcttctgat ggaaagtatg agcaggaaaa atctgattac
    41101 aaggagtgta agttggatat tactgattct catatcttga tgaagggaag agttaaggat
    41161 aatgatctgc ggtttgctag ttatctagct tgggaaacgg atggagatat tagagtttgg
    41221 tcagataggg ttcagatatc aggagccagt tatgccaatc tcttcttggc cgctaagacg
    41281 gattttgccc aaaatcctgc tagcaattat cgcaagaaac tagatttaga gcaacaggtg
    41341 atagacttgg tggacacagc taaagaaaag ggctataccc aattgaaatc aaggcatatc
    41401 gaggactacc aagccttatt ccagcgtgtt caattggatt tggaagctga tgttgacgca
    41461 tccactacag atgatttgtt aaaaaattat aagccacaag aagggcaggc tttggaggag
    41521 ctgttcttcc agtatggacg gtatttattg attagttcgt ccagagactg cccagatgct
    41581 ctaccagcta acctacaggg agtctggaat gcggtcgaca atcctccttg gaattcggac
    41641 tatcacttaa atgtcaatct gcagatgaat tattggccag cctatgttac caatcttcta
    41701 gagacggtct ttccagtcat caactatgta gatgatttgc gtgtctatgg tcgtctagcg
    41761 gctgtaaagt atgcaggaat cgtctctcag aaaggtgagg agaatggttg gttggttcat
    41821 actcaagcga ctccctttgg ttggacggca cctggttggg attactattg gggttggtca
    41881 ccagctgcca atgcgtggat gatgcaaacc gtttatgaag cctattcatt ttatagggac
    41941 caagactatc tcagggagaa aatttatccc atgttgaggg aaacggttcg tttttggaat
    42001 gcctttttac ataaggatca gcaggcgcag cgttgggtgt cttctccgtc ttattcccca
    42061 gaacatgggc cgatttcgat tggcaatact tatgaccaat ctctgatttg gcagttattt
    42121 catgatttta ttcaggctgc tcaggaattg ggactggatg aggacttgtt gactgaggtt
    42181 aaggagaagt ctgatttact aaatcctttg caaatcactc aatctggtcg aatcagggag
    42241 tggtatgagg aggaagagca gtattttcaa aatgagaaag tggaggccca gcatcggcac
    42301 gcttcccatc tagtaggact ctatcctggc aatctcttta gctacaaggg acaagagtat
    42361 attgaagcgg cacgtgctag cctcaatgat cgtggagatg gcggcacagg ctggtccaag
    42421 gctaataaga tcaatctctg ggcgcgtttg ggagatggca atcgagccca taaattattg
    42481 gcagagcagt taaaaacatc caccttgcca aatctttggt gtagccatcc tccttttcag
    42541 atagatggta attttggtgc tactagtggc atggcagaaa tgttactcca gtctcatgca
    42601 gcttatctgg tacctctagc tgccctacct gatgcttggt caacaggttc tgtttcaggc
    42661 ttaatggcac gtggacattt tgaagtgagc atgagctggg aagataaaaa actcttacag
    42721 ttgaccattt tatcaaggag tggaggagat ttgcgagttt cttatccaga tattgagaag
    42781 agtgtgatta aaatgaatca agaaaaaata aaagcgaaat gcatggggaa agattgtatt
    42841 tcggtggcaa cagcagaagg tgatcttgtt caattttatt tttaagaaga tgttataagg
    42901 cagtaatttg aaactgcctt ttaataagga tttaagaata taagcagttt tcaactagtt
    42961 gaaaaagcgt tataatgata ataggaagta atactcaatg aaaatcaaag agcacaaact
    43021 aggaagctag ccgcaggttg ctcaaaacag tgttttgagg ttgcagatgg aagctgacgt
    43081 ggtttgaaga gagattttcg aggagtataa tttgtttgat agagggtggg tctgatggct
    43141 tatattgaga tgaaacactg ttacaagcgt tatcaggttg gggacacgga gattgtggcc
    43201 aatcgtgatg tgaattttga gattgaaaag ggggagctgg ttattatcct tggtgcttca
    43261 ggtgcaggca agtcaacagt tcttaacctt cttgggggaa tggataccaa tgatgaaggg
    43321 gaaatctgga ttgatggtgt taatattgcg gattatagtt cccaccagcg caccaattac
    43381 cgtagaaatg atgtggggtt tgtttttcag ttttataatc tagtttctaa tctgacagct
    43441 aaggaaaatg tggaactggc ttctgaaatt gtgacagatg ccttgaatcc tgatcaggtc
    43501 ttgacagatg taggtctggc tcatcgtctc aataactttc cagcccagct ttctggaggg
    43561 gagcaacagc gagtctccat tgcacgcgcg gtagccaaaa atcctaaaat tctcctttgt
    43621 gatgaaccga ctggagcctt ggattatcag acgggcaagc aggttttgaa aattctccaa
    43681 gacatgtctc gtcaaaaggg agcgacggtg atcatcgtga ctcataatgg agctttggcg
    43741 cccattgctg atcgcgtgat tcatatgcac gatgccagtg tcaaggatgt ggtgctcaac
    43801 cagcatcctc aggatattga cagtttggag tactagcatg atcaagcgaa aaacttattg
    43861 gaaggactta attcagtcct tcacagactc caaggggcgt tttttatcca tcttgatcct
    43921 gatgatgttg ggatctctag ccttagtagg cctcaaagta accagtccca acatggaggc
    43981 gacagctaat gcttatttaa caactgctca aaccttggat ttggcagtca tgtctaacta
    44041 tggcttggat caagcagacc aagaagaact aaaacagacg gagggcgcag aggtcgagtt
    44101 tggctatttg acagatgtga ctatggataa tgggcaggat gccattcggc tgtactccaa
    44161 accagagcga atttcaacct ttcagctaag aaagggacga cttcctcagt cagacaggga
    44221 aatcgctttg gccactcatt tgcaaggcca atacagcgtg ggacaggaga ttagttttaa
    44281 agaaaaagaa gagggtcatt cctctttaaa agaccatact tataccatta ctggttttgt
    44341 ggattcggct gaaatcctct cccagcgaga tatgggctac gcaggaagtg gaagtgggac
    44401 tctgacagcc tatggggtga ttttacctag tcaatttgat cagaaagtct acaatatagc
    44461 tcgtttgaaa tatcaagatt tagcaggttt aaatgccttt tcatcagctt atgaagaaaa
    44521 atccaagcaa catcaggaag accttgaaca aactttatca gataatggca aggtacgtct
    44581 gcaacttttg aaaaaagaag gacaagagtc tctagacaag gggcaagaga cccttgacaa
    44641 ggctcagact aatttgcagg aaggcaagcg tcgtttagca gctgctcaag ctcgtataca
    44701 ggctcaagaa agtcaactag ccttgtttcc tcaagctcag agagagcagg ctagtgctca
    44761 acttacccaa gccaagcagg aactgggcaa ggaagaggac aaactaaagc aagctgaaca
    44821 aaatctagcc caagaaaagg aaaaattaga aaaacatcag caagtcttgg atgatttggc
    44881 ggagccaagg tatcaggttt ataatcgtca gaccatgcca ggtggtcagg gctatcttat
    44941 gtatagcaat gcttcatcca gtattcgagc agtgggcaat atctttcctg tggtacttta
    45001 tgccgtagca gccatggtga cctttacgac catgactcgc tttgtagacg aagagcgaac
    45061 tcatgcaggg atttttaagg ccttgggtta tcgtagtaag gatattatcg ccaagtttct
    45121 cctttatgga ctagtagctg ggactgtcgg aacggctcta ggtagtatac ttggtcatta
    45181 tttgctagcc agtgtaattt caagtgtcat tacaaaaggc atggtggtgg gagaaaccca
    45241 gattcagttc tattggacct atagcttact agctcttgtc ttgagctggt tggcgagtgt
    45301 gttaccagcc tatctggtgg cttggaggga acttcatgac gaagcagccc agcttctact
    45361 tcctaaacct cctgtcaaag gagctaaaat cttattggag cgtatcggtt ttatctggcg
    45421 tcgtctcagt tttactcata aggtaacagc ccgcaacatc tttcgttata agcagagaat
    45481 gttgatgaca atctttggtg tggcaggttc tgtagctctg ctctttgcag gtttgggaat
    45541 ccaatcttct gtagcaggag ttccgtctaa acagtttcaa caaatccaac agtatcagat
    45601 gcttgtctct gaaaatccta gtgcgaccaa tcaggacaag gtagagctag cagaagtatt
    45661 gaaagggcag gagatactag cctaccagaa aatctattct aaaacgctag acaaggattt
    45721 caaaggcaag gctggtcttc aaaacattac tcttatgatg atagagaagg aagatttgac
    45781 tccctttatc catcttcaac atcatcagca ggagctgaca ttaaaagatg gcatcgttat
    45841 tacagctaaa ctcgcccagc tggcaggtgt caaggttggg cagactttag aaattgaagg
    45901 taaggaacta aaggtcgctg ctattactga gaactacgtt ggtcacttta tttatatgag
    45961 tcaggctagc tatgagcaac tttacggaca gctaccccaa gccaacactt atctggtctc
    46021 attaagggat accagtgcaa ctagtatcga aagtcaggcg ggcttgctta tgaatcaatc
    46081 tgcggtgtcc agcgttgtcc aaaatgcttc agccattcga ctcttcgact ctatcgctag
    46141 ctcactcaat cagaccatga ccatcttggt catcgtatcg gttctattag ctattgtcat
    46201 cctttacaat ctgaccaata tcaacgtagc tgagagaatc cgtgaactct ccactatcaa
    46261 ggttctcggt tttcataata atgaagtcac cctctacatt taccgtgaga cgattgtgct
    46321 gtcccttgtg ggaatcgtac ttggtctgat agctggtttc tatttacacc aatttttgat
    46381 tcaaatgatt tcgcctgcga ctattctctt ttatccgcag gtaggctggg aagtctatgt
    46441 aatcccagtg gcagcagtaa gcatcatttt gaccttgctt ggtttcttcg tcaattatta
    46501 tctgagaaag gttgatatgt tagaagctct gaaatctgta gagtaaggta attattttta
    46561 gctgattgaa cttctattta ctaatattca aaaatcctcc gtttcaaaga gcagggaact
    46621 ctttgtgaca gaggattttt tctatagggc tttagcagct gcaattgcgg cttcgaagtt
    46681 tggctcagaa ttgatattat ccacgtattc aacgtagcga atcgtattgt cagtatcgag
    46741 gacaaagact gcgcgtgcta ataggtgcca ttcgttgatc aagagggcat aatcgcgccc
    46801 gaaagaatgg tcaaagtagt ctgaaagcat aatggcattg tcaaggcctt cagcaccgca
    46861 ccaacgtttt tgagcaaaag gtaggtccat tgaaacagtc aatacgaccg tgttgtccag
    46921 tccagccaat tcttcattaa aacgacgtgt ttgagttgag cagatacctg tatcgataga
    46981 aggaacgaca ctcaagactt ttttcttgcc atcaaaatca gccagagatt ttttagaaag
    47041 atctgttgta gtaagagaaa aatcaagcgc cttgtcgccg acttgtagtt gtttacctgt
    47101 aaagctcaca ggatttccga gaaaagttac cataggatac tccaatcttt tttcttccat
    47161 tgtatctaaa acagtcagaa ttttccaatg atttgaccgg aaatgtgtgc atagaaaaaa
    47221 cgccagctca catgagaatg acgtttttca gaggcttatt ttgccaatcc ttcagcaatc
    47281 ttgtcaaggt tgtatttcat catgctgtag tagctgtcgc cttctttacc ttgttctgcg
    47341 atagagtcag taaagatttg tgcgtagatt gggatgtttg tgtcttgaga aacagttttc
    47401 attggacggt catccacact tgattctaca aagagtgatg gaacttttgt ttggcgaagt
    47461 ttttcaacca aggtcttgat ttgttcagga gttccttctt cttcagtatt gatttcccag
    47521 atgtaggcac ttgggacacc ataggcttta gagaagtatt tgaatgctcc ttcgctggtt
    47581 acaatgagtt tcttttcagc agggatctta ttaaatttat ccttactttc tttatcaagt
    47641 ttgtctaact tatcagtata ttctttgaga tttttttcat agaattcttt attgttaggg
    47701 tctttggcgc tcaattgttt ggcgatattt ttagcaaaaa taataccgtt ttcaaggtta
    47761 agccaagcgt gtgggtcttc ttttcctttt tcattttgac cttcaaggta gataacatca
    47821 acgccgtcgc tgactgcgaa gtagtctttg ttttcagttt tcttggcatt ttctaccaat
    47881 tttgtaaacc aagcattgcc acctgtttca aggttgatac cgttatagaa aatcaaatca
    47941 gcctcagaag ttttcttaac gtcttcagga agtggttcgt attcgtgtgg gtcttgccca
    48001 atcggaacga tactatgaag gtcaattttg tcaccagcaa tatttttagt aatatcagcg
    48061 atgattgagt ttgtagcaac aacttttagt ttttgaccag aagttgtatc tttttttccg
    48121 ctagcacatg ctacaagaat gattgcagaa agaaagagaa cgagtaatgt acctaatttt
    48181 ttcattagat cctccaattt attagggctt tgccccttat tttaacaaat gtttattttt
    48241 cagtttcaaa tatcgttgtt tgggagcgat aaagaagcta atgagaaaga aactagcagc
    48301 tgtaagcacg atactagaac ctgccgcaac attaaaacta tagccaataa agagtcccaa
    48361 aactgaagca gtagctccga aggttgagga aaggaaaatc atacttttca gactattagc
    48421 atacagataa gcagttgcag ctggggtaat cagcatggct acaatcagga tagttccgac
    48481 actttgcatg gctgtcacag acacgagagt caggagtacc atgagaaggt agtgatagaa
    48541 attgacaggc attcccatgg ctttagccaa gagttcatca aaggaagtta tcaagagttg
    48601 cttgaagaaa atccagatta acaagaggat ggctgccccc acacccatag taataaacat
    48661 atccgtatct tggacggcca ggatattacc aaaaaggata tggaaaaggt cagttgaact
    48721 tttagcgaca ccaatcaaga tgataccgag ggctaagaaa gaagaaaagg taatgccgat
    48781 ggcggtatcg cttttgataa tcgagtttcc tttgatgtag gtaatgatga tggcagctag
    48841 caatccaaag acaatggctc cgataaagaa gtcaaggccc aagatgaagg agagggctac
    48901 acctggtaag acagcatgtg aaatggcatc tcccatgagt gacatcccgc gtagaataat
    48961 gaaacatccc acggctccag ctacaatccc gacgacaata gctgttatca aggcattttg
    49021 taggaaatgg aatttttgca atccatcgat aaattctgca atcataggtc acctccattg
    49081 aaaaagagtt gattaccgta agcttctttt agattggttt cggtaaaagt ttcttttgtt
    49141 ggaccaaagg caatcacttc tcgattgaca agtaagactt gatcgaagta gtggggaatc
    49201 ttgctgaggt cgtggtgaac gatgagaacc gtcttcccag cttttttcaa atctctcagc
    49261 gtattcatga tgatttcctc actgacagag tcaatcccag caaagggttc atccaagagg
    49321 atatagtcgg cttcctgcac caaacatctg gcaatcaaga cccgctggaa ttgacctcca
    49381 gacagttgac taatttgacg ttcagcgtag tcagctaggc cgacgatttc aagggcctct
    49441 tgcactttct tccaatgttt agcctttaaa cttcgaaaga gaggaataga gggaaatagt
    49501 cctaacgaga cgcattcctt gaccttgatg ggaaagttgt agtcgatatt gattttttgt
    49561 tcgacatagg caattcggtg taaggatttt ttaacttcct tgtcatcgag aaatgcctga
    49621 ccttgatgtg ggataattcc cagcatacct tttaatagtg ttgatttccc agcgccgttt
    49681 ggaccaatga tgccggtaat tgttggtcca tggagcacta gtgaaatatc cttaagtgcc
    49741 aacgtttctt tgtaggagac actgaggttt tcgatacgta tcataaactt gtattcctcc
    49801 tgtctcttaa tatacattaa aaaaaaaatt aagtcaagtt aatttttgaa aaaattaaaa
    49861 taataactga aaaatagatt ctaaagataa ctttcaggat aaatttctaa attataaaac
    49921 gcatagtatc aagtgtaaaa aacttggaat tatgcgtttt atcatggaaa gtttttttat
    49981 aatagctaaa aaataatagt taaatggtta ttaattgcat tccctagtga tttttgttaa
    50041 gataaatgca aatacaaatg aaagcgagaa caagatgaca cgttatcaag atgattttta
    50101 tgatgctatc aatggagaat ggcaacagac agctgaaatc ccagcagata agtctcaaac
    50161 tggaggtttt gttgatttag accaggaaat tgaagacctg atgctggcga caacagacaa
    50221 gtggttagca ggtgaagagg tgcctgagga tgctatcttg gaaaactttg tcaaatacca
    50281 ccgcctagtt cgtgattttg acaagagaga agctgacggt atcacacctg tcttaccact
    50341 ccttaaagaa ttccaagaat tggagacttt tgcggatttt acagctaaac tagcagagtt
    50401 tgagcttgca ggaaaaccaa acttccttcc ttttggtgta tcgccagact ttatggatgc
    50461 tagaatcaat gttctatggg ctagcgctcc aagcacaatc ttgccagata cgacctacta
    50521 tgcagaagaa catcctcagc gcgaagagct cttgactctt tggaaagaaa gcagcgcaaa
    50581 tctcctcaag gcttatgatt tctctgatga agaaattgaa gacttgctag aaaaaagact
    50641 tgaattggac cgccgagttg cgacagtggt gctctctaat gaagaaagtt cagaatatgc
    50701 taaactctat catccatatt cttacgaaga tttcaagaaa ttcgcgcctg ccctaccttt
    50761 ggatgacttc ttcaaagcag ttattgggca attaccagac aaggttattg tagacgagga
    50821 acgtttctgg caagcagcag agcaattcta cagtgaggaa gcctggtctc tccttaaagc
    50881 aaccttgatt ttgagtgttg tcaatctttc aaccagctat ttaacagagg atattcgtgt
    50941 tttgtctggt gcctacagcc gtgccctttc tggagttcca gaggcaaaag ataaggtcaa
    51001 agcagcttat catctagcac aggaaccttt caagcaagcc ctggggcttt ggtacgcccg
    51061 tgagaagttc tctccagaag ccaaggcgga tgtggagaaa aaagtggcaa ccatgattga
    51121 tgtctataag gagcgtctgc ttaagaatga ctggctcact ccagaaacct gtaaacaggc
    51181 tatcgtgaag ctcaatgtga tcaaacctta tattggctat ccagaagaat tgcctgcacg
    51241 ttacaaggat aaggtagtga atgaaactgc cagtcttttt gagaatgctc tagcctttgc
    51301 gcgtgtggaa atcaagcaca gttggagtaa gtggaaccag cctgtagact ataaggaatg
    51361 gggcatgcct gctcatatgg tcaatgccta ctacaatcct cagaagaacc tgattgtctt
    51421 tccagcggcc attttacagg cgcctttcta tgacttgcat cagtcatctt ctgctaacta
    51481 cggtggtatt ggggcagtga ttgcccatga aatttcccac gcctttgata ctaacggggc
    51541 ttcctttgac gaaaatggta gcctcaagga ttggtggaca gagagcgact atgctgcctt
    51601 caaggagaaa acacaaaaag tcattgacca atttgatgga caggattctt atggagcaac
    51661 cattaacggt aaattgactg tatcagaaaa cgtggctgac ttgggaggaa tcgcagcagc
    51721 gcttgaagca gctaagagag aagcagactt ctcagcagaa gagttcttct acaacttcgg
    51781 tcgcatctgg cgcatgaaag gtcgtccaga atttatgaaa cttttggcta gcgtcgatgt
    51841 gcacgcacca gccaaactcc gtgtcaatgt gcaagtacca aacttcgacg atttctttac
    51901 aacctatgat gtcaaagaag gagacggaat gtggcgttca ccagaggagc gcgtgattat
    51961 ttggtaatac aaaaaatcta gtcatcagaa aaaaggcatc caatcacgtg tgaaaacctt
    52021 gataggatgc cttttgtaat agaaagattt gctggatagt ttacttaaat ttcgattgtc
    52081 atcatcttgc tagaaaaagg gattgaaggc cttttcgtga gcgatagtag tagctggacc
    52141 atgtcctgga tagacatcgt agtttggtag ggtgaagagt tgggtctgga tactatgaag
    52201 gagttgctcc atgctaccag tcggaaggtc ggtccgtccg atagtttcgc ggaatagagc
    52261 atctcccgtc aagactaggt gagcatcagg aaagactagg gaaacaccac cgatagagtg
    52321 ccctggggtc ggtagaacct taaaacgaaa ttcctctagt tggtattctt cgtgaaagac
    52381 aaaggtgtgt tctgcaggtt ttgtgaccac atctgccata tcatcgtggc gagggagacc
    52441 ggagagatta tcgacaggag tgtagagcca gctggcttcg ctctctgcga tatagacagg
    52501 aggattgcca aacgtctcgc gaaccaagtc cagactcatg atatggtcat aatgggcgtg
    52561 ggtcaagaga atagcacaga tcggtttgtt gatcttctcg attgtctgac gaatggcttc
    52621 ccaatgacta ccaggatcga cgacgatgag gtgcttttcg ccttctagat aataggtatt
    52681 ttcataggca acaggattca cggttttatg gattttcata ctagctccaa tctcaaagaa
    52741 tgtactaata ctcttcgaaa atctcttcaa accgcgtcaa ctttatctgc aacctcaaag
    52801 cagtgctttg aacagcctgc ggctagcttt ctagtttgct ctttgatttt cattgagtat
    52861 aaattaagta tagcacagtt agggagaata ggtaaggatt taaaatgaac ttaaaaacca
    52921 gcatgactag atgaagacag gctggttatc aatttatcaa tattggaaag gtgtcaattg
    52981 cccttcatag gttgcataaa ctccgtcatt agcttgtttg atagacgtga tgtttagagt
    53041 gctaccgtag ttggcttctc atttgtcgct atattcacta taagttatcc tactgggcag
    53101 gttctggtcg ttagcatagt attgaacgag ttttttatag ctttgctggc tgaataggaa
    53161 caggcagcaa actcctaaca ttaggagagc aaagatagaa atagcagttt tttcataggt
    53221 attctcctta taaactaaag gatagaagaa agtatcttga ggatttttac actcttcaag
    53281 aatctcttca aaccgcgtca acgtcgcctt gccgtatata tgtgactgac tttgtcagtc
    53341 ttatctacaa cctcaaagca gtgctttgag caacctgcgg ctagtttcct agtttgctct
    53401 ttgattttca ttgagtatta attccaaaat ccagtcaagg taccagtgta tgtgatacga
    53461 gttccaccgt ttatctttcg tatcttcaat ggaattgggg aaatcagaaa gtctttgggt
    53521 tacaatatgg tttccgttct tctatctctc cttctatcac ctaagtttaa aatctaactt
    53581 cgtagtatat tatgggccaa taattcagaa ttatcaagca attttgaatt atttttttct
    53641 tattctgttc caatctagtt ttcatattct taaaaaagtg ataaaatggt aggaagaatt
    53701 ggagagtaga gatgccgaaa gaagtgaatt taacaggcga agaagttgtc gctttaacca
    53761 aagaatattt aacggaagag gatgttcatt ttgtccataa ggccttggtc tatgctgttg
    53821 aatgccacag tggtcaatat cgcaaatcag gcgagcctta tatcattcac cctatccaag
    53881 tggcaggtat tttagctaag ctaaagctgg atgctgtaac agtagcttgt ggattcttgc
    53941 atgatgtggt ggaagataca gatgcgacct tggacgattt ggaaagagag tttggtcctg
    54001 atgtgcggat gattgttgac ggagttacca agcttggcaa ggtcgagtac aaatcgatcg
    54061 aggagcaatt agcggaaaat catcgcaaga tgctcatggc catgtctgag gacatccgcg
    54121 ttattttggt caaactgtct gaccgcttgc acaatatgcg gaccctgaaa catcttcgaa
    54181 aagacaagca ggagcgtatt tccaaagaaa ccatggaaat ctatgccccg cttgcccatc
    54241 gtttggggat ttccagtgtc aaatgggaat tagaagactt gtctttccgt tatctcaatc
    54301 caacggagtt ttacaagatt acccatatga tgaaggaaaa gcgcagggag cgtgaggcct
    54361 tggtggatga ggtagtcaca aaattagagg agtatacgac agaacgtcac ttgaaaggga
    54421 agatttatgg tcgtcccaag catatttact caattttccg caaaatgcag gacaagagaa
    54481 aacggtttga ggaaatctat gatctgattg ctattcgttg tattttagat acccaaagtg
    54541 atgtttatgc catgcttggt tacgtgcatg aattttggaa accgatgcca ggtcgcttca
    54601 aagactatat tgccaaccgc aaggccaatg gttatcagtc tatccatacg actgtttatg
    54661 gaccaaaagg gccgattgaa ttccagattc gaaccaagga aatgcacgag gtggctgagt
    54721 atggggttgc ggctcactgg gcttataaga aaggtataaa ggggcaagtt aacagcaagg
    54781 aatcagctat tggaatgaac tggatcaagg agatgatgga gctccaagat caggctgatg
    54841 atgctaagga atttgtggac tctgttaagg aaaactatct ggctgaggag atttacgttt
    54901 ttaccccaga tggagctgtc cgttcccttc ccaaagattc aggaccgatt gattttgcct
    54961 acgaaatcca taccaaggtc ggtgaaaaag caactggtgc caaggtcaat ggccgcatgg
    55021 ttccactgac aaccaagtta aagacagggg atcaggttga aattatcgcc aacccgaact
    55081 cctttggacc tagccgtgac tggctcaata tggtcaagac tagcaaggcg cgcaataaga
    55141 ttcgccagtt ctttaaaaac caagataagg aattgtctgt caacaagggt cgtgagatgc
    55201 tgatggctca gttccaagaa aatggctatg tggcaaataa atttatggac aagcgccaca
    55261 tggatcaagt tctgcaaaag accagttaca agacagaaga ctccctcttt gcggccattg
    55321 gttttgggga aatcggtgcg attaccgtct ttaaccgtct gactgaaaag gaacgccgtg
    55381 aggaagagcg tgccaaggcc aaggctgagg cagaggagct tgtcaaaggt ggcgaggtca
    55441 aggttgaaaa taaagaaacc ctcaaggtca agcatgaggg gggagtggtt attgaaggtg
    55501 cttctggtct cctagtgcgg attgctaagt gttgtaaccc cgtgcctggt gacgatattg
    55561 ttggctacat taccaagggt cgtggtgtgg ctattcaccg tgtggactgt atgaacctgc
    55621 gtgcccaaga aaactacgag caacgtctcc ttgatgtgga atgggaagac cagtactcta
    55681 gctcaaataa ggagtatatg gcccatatcg atatctacgg tctcaaccgt acaggactgt
    55741 tgaacgatgt actgcaagtt ctttcaaata caaccaagaa tatttcaacg gtcaatgccc
    55801 aaccaaccaa ggatatgaag tttgctaata tccatgtgtc cttcggtatt gccaacctct
    55861 ctacactgac tacggttgtc gataaaatta agagtgtgcc agaagtttac tctgtcaaac
    55921 ggaccaacgg ctagttgtcc tagctcttac tagaaaggct attatgaaaa tcattatcca
    55981 acgggttaaa aaagcccaag tgagtataga aggccagatt cagggaaaaa tcaatcaggg
    56041 acttttattg ctggttggtg ttggaccaga ggaccaagag gaagatttgg actatgctgt
    56101 gagaaaactg gtcaatatgc ggattttttc agacgcagaa ggcaagatga acctatctgt
    56161 caaagatatt gaaggagaaa tcctctctat ttctcagttt accctctttg cggatactaa
    56221 gaaaggcaat cgtccagcct ttacaggggc agctaaacct gatatggcat cagacttcta
    56281 tgatgctttc aatcaaaaat tagcgcaaga agtgcccgtt cagacaggta tctttggagc
    56341 agatatgcag gttgagctga ttaataacgg acctgttacc attatcctag atactaaaaa
    56401 gagataagaa agaccaagcc cagtcggctt ggtctttctc atagatcata aaatactcca
    56461 aaaagaaatc ggttcttgat atgcttgggg gaagtctctt ttcaggcttt ggcagatgcg
    56521 ataggaaggg atgagatgtc ctaggatgag gagagttccc tgaaggaaaa gcggaatatt
    56581 acttaaagac accaaggaga gaatcatcag gctatcccat aggagaattt gtaaagcaaa
    56641 acgccagaat ctcggtctaa tctgggaata gagttaacta aagtggtcac aaagttggtt
    56701 tgaaagatag gtcaatagca caggatgaaa gaaaatgagc caaccgctat aaatcaaaat
    56761 ccagtcccaa gtaagccccc cttttaaatg tcaaaaatgc cagcatgatt ccatcaatga
    56821 caaggagttg aatggttttg atgaagatga tttttttcat gctaaaacct ccttttcctt
    56881 agagacactc ccataaagag atgtgtttgt cgtaaaagtc tggatagttt tctcttaggt
    56941 agtcagctgt catataataa aaagtagaat ggcaagcagt gatgattggc ataagagatg
    57001 aaaaacgctg agaactaatg aaggctaaga gaacaaaaaa tagaaaatca atggtgagaa
    57061 cccctaaata gtagaagcga atctttttat tgatttgagg ataaatctca gcgaattgat
    57121 gtttgagtcg gacgatcaag agaaatagca ggagtccttg agcaaggaag aaaattaaac
    57181 cagagagcaa gagccactca aaagatgtct cgagtctaat gataaaaaat gcaaatagta
    57241 gcaaatcaat aactgcaatt gctataaaat ggattctata gagttttttc atgacaagac
    57301 ctccctcttt tatctaactt cattctactc caaaagaatg ggagttacaa ctaaaatgat
    57361 aaaaatagca gaagggagat tctcttaagt tggctagtat tctttatttg agtttccttc
    57421 tattatctaa cttcttcatc attccagaca aataaagctc cgattgcatt gaggatataa
    57481 aagatgtatt taccgatatt ggcgaagttt ccttgaatac cagcttttgt cagctgaacg
    57541 aaattgtaaa tcaaccaaaa gccccactga gttgttagtt ttaatgcatt caaagcattg
    57601 gcaatgaggg atagtgcaaa ggcaatagtt gttacgtagg caaggagatt catcttgccc
    57661 tcatatccga tatagttggt cacaaaggca aagaggaagg cgatgatgga aatgatgatg
    57721 accgccaatt ttacctgttt ttggctcatt tggttgggtc tgccttcttg cgaagctttc
    57781 catttcttta tagcaaaggt ataaatgagg aaggtgacgg gataggtaat gatggccgcc
    57841 ttatttccaa ggatataatc aatagcaccg gacaaaatgg tattaacaat actaaagtaa
    57901 tttccccatt tgcttaattt ccccgtgaaa cgagtggaca acatggaaat cccaacgttg
    57961 gttacggaaa tcaatccaaa gggtacaaga gctgtccatg gtccccagtc tacaaattta
    58021 tcgaggcgtg agttgaggta accagatgca atcgcaatcc caacgaccaa agcaaccccg
    58081 aagaggtcaa accatttaga tgtagcaaaa atttttagtg attttttcat aggttaaact
    58141 acctttcttt ttttcaaata ttctcgcacc aaatgaaagt aaaataaaat gatagaaata
    58201 aaaccctgaa aataaaactt tcagggttgg taggggactt gagaaattag ttgattttct
    58261 cgacatagag ttgttttgca atgtccatat tcacttgtaa atcctcgtcg ttactgagga
    58321 tagtgaaggt attgctgaag ccatcaaact gcttgacttg gagctggtca ccgatgtgaa
    58381 gtgagtgctt gtccagataa tggagaatgt caaaattatc gtgcacccga gtcaggcggt
    58441 aggcgccagc ttccttgata tcagctagtg ggaggttatt gatttcaacg aggagttctc
    58501 ccttggcagg aatagttcct ccgtgggggc aggttttagg gaaacctagc agtttatcta
    58561 gtctttccac gaacaggtca gagacagtgt gttccaagac ctcagcttcc tcgtgaatct
    58621 ggtcacttgt atagtctaaa tgatgaacta gaaaaacttc aatcaagcgg tgcttacgat
    58681 agagctcaga gaccagtttg agaccgaggt cagtcagtag atagccacat tccttgtcct
    58741 ttaggatgag attttcactt ttcattcgtt tgatcatttc agttacggca gggggagaga
    58801 cttgcatgcg agccgcaatt tccttgttgg taatcttatg caggtctatg ccaatttcat
    58861 aaatacattt tagatagtct tctttgtttg gggtcattcg tttcctcttg tctaatatct
    58921 ttatctagta tatcaaaaaa agctagattt ctctagctgt gactttttat gttatactta
    58981 ttgcaagaga aaaaacgagg agatggatat gacaaaaata gctcttcttt cagatattca
    59041 tggaaatacc accgccttgg aggctgtttt ggcagatgct cagcagctag gagtggatga
    59101 atactggctt ttgggagata ttctcatgcc agggacagga cgtagaagga ttttggactt
    59161 gttggatcaa ctaccgatta cggctagagt tttgggaaac tgggaagaca gtctttggca
    59221 tggtgtccgt aaggaattgg acagtactcg ccccagtcaa cgctatctct tgcgccagtg
    59281 ccagtatgtt ttagaggaaa tttccctaga agaaattgaa gtgctccaca atcaacctct
    59341 tcaaattcat cgtcagtttg gggatttgac ggtgggaatt agccatcatc tgcctgataa
    59401 gaactggggg cgagagttga ttcatactgg caaacaagag gagtttgacc gcttggtgac
    59461 tcatcctccc tgtgatattg ctgtttatgg acatattcac cagcagttgc ttcgttacgg
    59521 gactggtggg caattgattg tcaatccggg ttcgattggc caacctttct ttttggacgc
    59581 tcagctacgg aaggacttgc gggcccagta tatgattttg gagtttgatg acaaaggcct
    59641 ggtagatatg gacttccgac gggtagacta cgatgtggca gcggaattgc agctggctaa
    59701 agacctgaga cttccctatt ttgaggttta ctatgaaagt ctggtcaatg ggatccacca
    59761 tactcatcat caggaatttt tgagagaatt ggctcagaaa gagggctgcg accgggagtt
    59821 agacgactgg ttgaaaagtg gtaacgattg acattacaac taaaaagggt ataataatag
    59881 aaaaagaaga gtagaggcag ggtagcctcg taaaaaggag aagaggatgc aaattccaag
    59941 tagatttacc attgcgactc atatgctgat aatcattgcc ctcgagggga aggaaagcaa
    60001 ggtgaccagt gattttctgg ctgctagtgt cggggtcaat cctgtcatta tcagaaagat
    60061 cttgtcccag ttgaagaagg cagagctgat ttcagtagcg cgtggaacgg gcggaacaga
    60121 gattgtcaag gaccttaagg atattagtct tttagatgtt tatcaggcgg tcgaatgtct
    60181 tggtaagaca ggtcaactct tcagtttcca tgacaatccg aatccaaatt gccctgtagg
    60241 agctcatatt catgatgttt tggatcaaaa attggagaga attcagttga ctatggaggc
    60301 agaacttggt cagaccagtc tagaaaaagt cgtggccgat gcagagagtc agatgaagga
    60361 ttaagaggga taaatgccct ctttttttct ttggataatt atgataaaat gtagctatta
    60421 aaggagtaag aaatgtatct cgttatagaa attgtattag cctttatagt gtcattttgg
    60481 aaggataata gaagtttgtg gaatccagta ttatttttat tatccctcat ttcaagttat
    60541 ttttatctat cctacctttt ttataaaaat ggatacgaga atgttcagtt agctttttat
    60601 gtatttgcct ttgtcttact tccttttttg ctttttctaa gtggcatctt tttaatctat
    60661 aatggggtca ttttgttgaa acgagaggga cgttccaagc cccattatct ctcaatgctc
    60721 tttgattttt attgactatt agattctatt taaaaagact tagaatgcac atgaaagtat
    60781 gtattctagg tcttttgttt tgtatacatt taattttcaa gagtattatc tatttttcca
    60841 tgcatggtaa cgagtatcaa tcaataactg ggtaaggcga cccaaggttt ctctttcttc
    60901 tggagtgagg gattgagctt ggacaaagag atgatgaatg tattcaagcg cctttaagga
    60961 agccaagtca ttgatagagc taataccagc atcaagaata gtgccaaaga agaggtcgaa
    61021 gtagagctga agttcttcgt cagggactgt ggccacccat tctttaaagg ttgtgtctac
    61081 ttgccggcta tcactgttgg tcttatccag ttgaacgaag tgcttgtcct caatctgcca
    61141 actaaaggta tcgtgctggg cgatgccacc cagggcagta ctctgaacga tgatttggtg
    61201 agcaggaatt tccagcatca taccgataat ggaaccttgt ggaatgaata tcttgcttct
    61261 atccattatc ctttgataac ccgcagtctg tgtcaattct tgatggagac caggtgcatc
    61321 aaatgtataa actgctgtga tctgattttg caaactttgc tcaatttggc tagcagcata
    61381 gatagcgaga tttcctccct tggaatgccc agccagaata accttttgct taggatgatg
    61441 ggcaaaaaag ttctttaaat agcgaagggc gtgcttttga gcaggaattt ccttcatata
    61501 ggtcaggtgg aaatcttcct tccagccaat gatactgtca tctgtcccac gaaagacaat
    61561 cagataggta tcgaggctga cacgataagt catagccgca aattgctttt gcagttcagg
    61621 gtcgatgtcg ttgataaaat gggagagttt gcaatttttg aagcgcttgt gttgagccaa
    61681 ttcatctaat aattgaaggc gatttttgct agtaagcatg gtgggctctc ttggaacctg
    61741 aggtgctaga tctaaaagac gttgaggaag tgtggagacc agattatcaa aggagaggta
    61801 ggtgatttct attaaggtta gaatgtctaa ctcatttaag ggaaggtcgt aataagaatc
    61861 atatgcgaca tctttcagat agtcaaaaat attggccata agagctcctt tctttttatt
    61921 tatcttagca aatttccctc aaattagcta gtagcatagc ctgtttgtac tggctaaaaa
    61981 caggctattt caaattcagt ttcagaccat ctagcatgga aaaatctgtt ataataatgg
    62041 aaaaggagaa gcgcatgcac aagattttat taatagaaga tgatcaggtc attcgtcaac
    62101 agattgggaa aatgctctct gaatggggat ttgaagtggt cctggtagaa gactttatgg
    62161 aagttttgag tctatttgtt cagtcggaac ctcatctggt cctcatggat attggtttgc
    62221 ccttgtttaa tggttatcac tggtgtcagg aaatccgcaa gatttccaag gtacctatca
    62281 tgtttctttc ttcgagagac caggctatgg atattgtcat ggcaatcaat atgggggcgg
    62341 atgactttgt gaccaagcct tttgaccagc aggttctttt agctaaggtt cagggcttgt
    62401 tgcgtcgttc ctatgagttt gggcgtgatg agagtttgct ggaatatgct ggtgttatcc
    62461 tcaataccaa atccatggat ttacattatc aagggcaagt cttgaatttg accaagaatg
    62521 aattccagat tttacgcgtg ttatttgagc atgcaggcaa catcgtagca cgtgacgacc
    62581 tgatgcggga actttggaac agtgactttt tcattggtga taataccctc tctgtcaatg
    62641 tggctcgttt gcgtaaaaag ttggaggagc agggattggt aggatttatc gagaccaaga
    62701 aaggaatagg gtacggattg aagcatgctt gattggaaac aattttttct agcctatctg
    62761 cgctcccgta gtcgtctttt tatctatctg ctttctttgg catttcttgt cttactcttt
    62821 cagtttttat ttgccagtct aggaatttac ttcctctact ttttcttctt gtgttgcttt
    62881 gtaaccatat tatttttcac ttgggacata ttggtggaaa cgcaggtcta tcgccaggaa
    62941 cttctctatg gagagaggga agccaagtct cctttggaaa tagctttagc agaaaaatta
    63001 gaagcgcgtg agatggaact ctatcagcag aggtcaaaag cagaaagaaa actgacggat
    63061 ttgctggatt actatacctt gtgggtccat cagataaaga cccccattgc agccagtcaa
    63121 ctcttagttg cagaagtggt cgaccgccaa ctgaagcagc agctggaaca ggaaattttc
    63181 aaaatcgact cctataccaa cctagtttta cagtacctgc gtttagaaag tttccatgat
    63241 gatttgctct taaagcaggt tcaaattgag gacttggtca aggaaataat tcgtaaatat
    63301 gctcttttct ttattcaaaa aggcttaaat gtcaatctac atgaccttga taaagaaatc
    63361 gtgacggata aaaagtggct gctagtggtt attgagcaaa tcatctcaaa cagtctcaag
    63421 tacaccaagg aaggtggtct ggagatttat atggatgacc aagagctttg tatcaaagat
    63481 acgggaatcg ggataaaaaa cagtgatgtc ctccgagtat ttgaacgtgg cttttcagga
    63541 tacaatggcc gtttgaccca gcagtcctct ggacttggcc tttatctatc taagaaaatt
    63601 tctgaagaac tggggcacca gattcgtatc gagtctgagg tcggaaaagg aacgacagtg
    63661 cggattcagt ttgctcaagt gaacttagtc cttgagtaaa aatagatgag aaaaagcctc
    63721 cagattggag gcttttatgc tagactctta tttctcaacg cgtgatttgt tggcgatatc
    63781 agctaggata gcttgaacaa aattatcaac tgagacagtt tgtgtttctt tttggccgta
    63841 gcgacgaacg ttgactgttt cgtcttccat ttctttgtct ccaacaatta attggtaagg
    63901 aatcttgctg gtttgtgaag cacggatctt gaactgcatt ttttcattgc gctcatctac
    63961 gtctgcacgg acaccgcggt cacggagttt cttggccact tcccaagcgt agtccacgtg
    64021 tttttcgtta gatactggga tgagggttac ttggtgtggt gccagccatg ttgggaaggc
    64081 ccccttgtag ttctcaatca agatagctgt gaagcgttcc atagttgaga taaccccacg
    64141 gtggatcatg actggacggt gatcttcgcc atcagctccg atgtatttga ggtcgaagcg
    64201 ttctggcaac aagaaatcaa gttggatagt agaaagggtt tcttcttttc caagggcagt
    64261 tttaatctgg atatccaatt ttggtccgta gaaggctgct tcaccttcgg cttcaaagta
    64321 gtccacgccc atttcatcaa gagctgcacg aagcatggtt tgggcatttt cccacatctc
    64381 atcgttatca aagtacttat gagtatcttg agggtcacga agagagaggc ggaagcggta
    64441 gtcagtcaag ttgaagtctt cataaacatc gataatcaac tgaagggcac gttggaattc
    64501 ttcttggatt tgttctggag taacgaatag gtgaccgtcg ttgagtgaca tttcacgtac
    64561 acgttgaagg ccagtgaggg caccagattt ttcgtaacgg tgcatcatac cgatttcagc
    64621 gatacggatt ggcaattcac ggtaagagtg aacatggtgt ttgaaaactt ggatgtggtg
    64681 cggacagttc attggacgaa ggacaaattc ttccccgtca cccatgtcca tggttgggaa
    64741 catgtcttct tggtaatgat cccagtgacc agaagtcttg taaagctcaa cagaagcaag
    64801 tggtggagtg tagacgtgtt ggtagccaga agccaactct ttgtttacga tgtagcgttc
    64861 caattcacga cggatagtcg caccatttgg taaccagaat ggcaaacctt gtcccacttc
    64921 ttgtgaaatc ataaagaggt caagctcttt accaagttta cggtggtcac gttccttagc
    64981 ttcttcacgc atttgaaggt agtttttcaa gtctttcttg tcaaaccaag ctgtaccgta
    65041 gatacgttgc atcatagcgt tgtcgctgtt tccacgccag tacgcaccag ctacatggag
    65101 aaggtggaag atttggatac ggcctgttga tggaacatga ggtccacggc agaggtctac
    65161 atattcaccc tgacgataga tagtcaaacc gccttcgtct tctgagtgtt cttcaatcaa
    65221 ttccaacttg taagggtcat ttttgaagat ttcacgtgcc tcgtctttag tcacttcttc
    65281 acgaatagat gggaagtttt ctttgacgat tttttgcatt tcttcttcga tacgaggaag
    65341 gtcttcgtta gagatttgac cagctgtgtt gtcagtatcg tagtagaaac catcttcgat
    65401 ggctggacca actcccaagt gaatgtctgg gaaaagacga cgagctgctt gggcgaacaa
    65461 gtgagctgct gagtgacgca agattggaag ggcatcttcg tgatcaggtg tcacaatttc
    65521 gatgcttcca tcttcagtga tagcgcgagt agtgtcgatg agtttgccgt tgaatttacc
    65581 agccaaggct tttttagcta gggaattgct gatagattgg gcaatttcaa aagttgttac
    65641 gccagattcg aattcacgaa cagcgccatc tgggaaagta atgttaatca tgatgttctc
    65701 cttttttatt atttcatagt ttctaagcat tgatttttta tcagcagact acttccgagt
    65761 cctaacgttc aattgctttt ctttatcaga gaggaagttt tccatttccg tcagaatgtc
    65821 tatatccaaa cgttgagaaa gttctaatag ccaccagata ttttctgaaa gtttttgttc
    65881 cagtgtgtag ggtgtttcat catagtagcg tccttgcttt gtcatcacca gtcattggaa
    65941 atttccaata tcattagata aagccaagag gtcttcttct accgtccact tgaaatcatg
    66001 atgcttaact tccagttcgt gataagcttg tcggattgcc caactgcgct ccactaattc
    66061 ttgcaactcc ataattagta tcctaataaa aaaatgcgac atcctcgaaa ggacgtcgca
    66121 acgtggttcc accttcattt atgtacctca aaagagaggg acacctctga tcggctctaa
    66181 cgtggccacc gttttatgtt ttcataaaaa actcaagagt agtatcagtt tagacttcct
    66241 atgcgtttcc agcaaccacg cactctctag tagaaaggga ctaagtgact tgtctctatg
    66301 gattattata gcatgattgt gagatttttc aaggattttg tgaaagtttt ttgtttttca
    66361 ttttttgtag aatatgcttg atgctaatac cagaatccat gccgaccaga gcaactgttt
    66421 catagattag caagtaaatt agtataaact caccaaaggt tatgatagta aagtaaaaga
    66481 gcagtccgtt accaactaac catcaaagtg agaaacggaa acagtagcta tagagtaacg
    66541 atataatcaa gattaccaga ggtgtaaaga agagaagatt gtttatatag agttccttga
    66601 gtgtaagggg gtcagaaaca actagtaaga acaactcata aagtggccaa taaaagaata
    66661 atatgaccag atagtagggg agatgggaat agaatctacg catgataatc acctcgtttt
    66721 aaaaaaacag acaacttaga tctcttgcta tgattattat agcatgttta aaacaagaaa
    66781 gtaaatttgt tgacaaagaa gatttttctt ttcactagaa tcatagttag ttttcttggt
    66841 agaaatattt tgataataat taagcaagac tattgacatt gattattaag agtgtcacaa
    66901 ttattgtaac taaaataatt acaacaagag aggtataaaa aatgaaacta gcagttattg
    66961 cagcaaatgg acaagcgggg aaagcaattg ttgaagaagc agtcaaacga ggacatgaag
    67021 taacggctat tgttcgttct gaaaacaaaa gtcaagctga gtctattatt aaaaaagatt
    67081 tatttgagtt gacaaaagat gatcttactg gatttgatgc tgttatttca gcgtttggtg
    67141 cttatacacc agatacgcta ccgctccaca gcaaatcaat cgaactattt aatcagcttc
    67201 ttgctggaac acagacacgt tttctagttg tagggggatc aggaagcttt tatatagatg
    67261 aaacaaaaac gacacgactt ttagatacgt ctgattttcc tgaagaattt aagccactag
    67321 caaaagctca agcggatgaa ttggatcttc ttcgtacaaa aaataatctc aactggactt
    67381 ttgtcagtcc tgctgtagat tttattcccg atggtgaaaa aacaggaaac tacattctag
    67441 caggagaaat ttttactact aatgaaaaag gaataagcca gattagttat gcagattatg
    67501 ctattggatt ggtagatgaa cttgaaaaag gtcatcatat aaaagaacgt atctctttac
    67561 ttgaaaaata ataactatga gagtattaat gtttgacaga aaatttaaat cttggtaaaa
    67621 tagggattgt cgtaaagaca aataacttct tcttggttac aggcatgcca acctgtcact
    67681 cggatgaagc caaataaaaa ggagaaacat catggcaatc tcaaaagaga aaaaaaatga
    67741 aatcatcgca caatatgcac gtcacgaagg tgatacaggt tcagtagagg ttcaagttgc
    67801 tgtccttact tgggaaatca accaccttaa cgaacacatc aaacaacaca aaaaagacca
    67861 cgctacttac cgtggattga tgaaaaaaat cggtcgccgt cgtaacttgc ttgcatactt
    67921 gcgtaaaaac gacgttaacc gttaccgtga gttgatcaac tctctaggac ttcgtcgcta
    67981 attcaagata caaatgctgt caaaagtaca aagcaaaaat aggaaaattg acgaagaaac
    68041 ttcagtttct aggagatttt atcttttttg ccaagtgctt aggccgtgtt caattgagca
    68101 tatcttgata atgaagctac tctaaattgg gtagctttgt tgcgttgtca ccttacctcg
    68161 ctatactcaa gtatagtctt cggttacggt tcctagcact gtaaggtaaa ataaaccagc
    68221 ttttctccct tcggggagat ttttttgttt cactgaaagt ttcgtacgat cttcgcctcg
    68281 tcgcctagtc tataaacgat ttatctagca agaatcatga tgctaagggc gtcaaaaatc
    68341 cgtatgaaaa tagggaaatg acacagtgtt cgatgagcac aaggagtttc atctttttca
    68401 ctaggatttt agcccgggct caaatcagct ctctgacttc agagggcttt tttattgagg
    68461 ttttatcggt aacaattttg gagactacaa aaacctcaaa tggtatcagc taattacacc
    68521 ataaaggtgc gcagttactc ggcttttcaa gccgagtagc tgtatgcaag ccccctagaa
    68581 gagcccactc tttacaaagt aaagtatagt atgttatact ttacatggaa gtagtcactg
    68641 aattccagtt agaaattact ttgtaactac gttttgagga ggagtaaaat gctttcctac
    68701 gttcgatatt acccactagc gatagctaaa ttaatgtgtc tgtgctctcc taaaatctgc
    68761 tgatttatta ctgactaata caggaggttt tttttatggg acagacaatc atatctgcta
    68821 ttggtgttta tatttccacc agtattgatt atttaattat tttaattatt ttatttgcac
    68881 agctatcaca gaataaacag aaatggcata tttatgcggg gcaatatcta ggcacaggct
    68941 tacttgtagg ggcgagttta gttgctgctt atgtcgttaa tttcgtgcct gaagaatgga
    69001 tggttggatt gcttggttta atccctatct atttagggat tcgctttgca attgttggag
    69061 aagatgcgga agaagaagag gaagaaatta ttgaaagatt agaacaaagc aaggcaaatc
    69121 aactgttttg gacagttaca ttgctgacaa ttgcgtctgg cggagataat ttaggtatct
    69181 atatacctta ttttgcttcg ttagattggt cacagaccct cgtggccttg cttgtgtttg
    69241 taatcggcat aattatcttt tgcgagatta gtcgggtgtt atcctctatt ccgttaatat
    69301 tcgagacaat tgaaaaatac gagcgaatca ttgtgccctt agtattcatt ctacttggac
    69361 tatacatcat gtatgaaaat ggcacgatag agacttttct gatcgtgtag atttttttgt
    69421 ttcactagga ttttagcccg agctcaaatc agctctctga ttttcagagg gctttttcat
    69481 tgagtataaa tggacaatct taaagttact ctattgtaga gtggcttttg atttgattag
    69541 gagattctta taaatatagt aaaatgaaat aagaatagga caaatcgatc aggacagtca
    69601 aatcgatttc taaaaatgtt ttagaagtag aggtgtacta ttctagttcc aatctactat
    69661 ataaatgaaa accttagctg tttggccaag gttcatttct tctatgcaag ttcttctctt
    69721 ttcttatctg ggttccagat gaagcttgcg ataaagctaa agatgatggt taggatagcg
    69781 aggataatag caaggatgag ggcagggatg cggataaacc accagagtgg atttggtttt
    69841 ttatcattgt gccattgttt cgtttcttcg tccagacgtt ggaattctgt ttgaatacga
    69901 ttggcgactg tttcaatgcc ttcatcattc attttcttga tatctgagat atcgattgga
    69961 tttccaaagt tcatatcgac acgttcacgg ctaatcaagc ccttcaaagt catgggaccg
    70021 gtgtaggtaa ccggcatgat acggaccttg gccattttgg caatcagtgc tgcgcccccc
    70081 ttgacatcgt ttgagtggcg gctaccactt ggaaacatga tgagagagcg gtcacttttt
    70141 ttgagaacgt tgataggata tttgatggct gaggcgctgg gattttcacg gtcgatggga
    70201 aaggcgccac acatacgaat ccaccaacca aagatacggt tggtaaagag ttcttttttt
    70261 gccataaaga tgaactgttt tggcttggtc gcaaaggcca tataaacagg atcccaccag
    70321 gtacggtgag gcgcaactaa aatataattt tcatcttgat taggaatttt atcagtatta
    70381 tgatagtgag cattgccatt gatggaccat aagagcaaca caactaatcc acgcaaataa
    70441 gtataaaaca tgcgatctcc ttcgattgtt ttcttgttat tattatacct tatcaaagga
    70501 gggctggcaa acttttccct tgactagatg catatttggg atgagattag aattctgtta
    70561 aaaaaaatga tataatagaa tttatggata aaaataagat tatgggatta acccaaagag
    70621 aagtcaagga aagacaggct gagggtttgg tcaatgactt taccgcatca gccagtacca
    70681 gcacttggca aatcgttaaa cgaaatgtct ttaccctttt taacgctttg aactttgcca
    70741 ttgctttggc ccttgccttt gtgcaggctt ggagcaatct ggtcttcttt gctgttatct
    70801 gctttaacgc tttttctggg attgtgaccg agctacgagc caaacacatg gtggacaagc
    70861 tcaatctcat gaccaaggaa aaggtcaaaa ccatccgtga tggtcaggaa gttgctctta
    70921 atcctgaaga attagtgcta ggagatgtca ttcgtttgtc tgcaggagag cagattccta
    70981 gtgatgcctt ggttttggaa ggctttgcgg aagtcaatga agccatgtta acgggagaaa
    71041 gtgatttggt gcaaaaggaa gttgacggct tacttttgtc aggaagtttc ctagccagtg
    71101 ggtcagtttt agctcgtgtc catcatgtag gtgcagacaa ctatgccgcc aaacttatgc
    71161 tggaagccaa gaccgttaaa cccatcaact cccgtatcat gaaatcgctg gacaagctag
    71221 caggttttac tgggaagatt atcattccct ttggtctggc tctcttgctg gaagccttgc
    71281 ttttaaaagg cctgcctctc aagtcatctg ttgtaaattc gtcgacagcc cttttgggaa
    71341 tgttgcctaa gggaattgcc cttttgacca ttacttcgct cttgactgca gtgattaagc
    71401 ttggcttgaa aaaggtcttg gtgcaggaga tgtactctgt tgagaccttg gcgcgcgtgg
    71461 atatgctctg tctggacaag acgggtacca tcacccaagg aaagatgcag gtggaggctg
    71521 ttcttccact gacggaaact tatggtgaag aggctgttgc cagcatcctg accagctata
    71581 tggcccatag tgaggataaa aatccaacag ctcacgccat tcgccagaga ttccaaggtc
    71641 aagtagtcta tcctatgctc tctaatcttc ccttctccag cgaccgcaag tggggagcca
    71701 tggagttaga aggtttggga atagttttct taggggcacc tgagatgttg ctggattctg
    71761 aagtcccaga agccagggag gccttggaga gaggttcacg tgtcttggtc ttagctctca
    71821 gtcaggagaa attagaccat cacaaaccac agaaaccatc tgatattcag gctctagcct
    71881 tgctggaaat cttggatcct attcgagagg gagcggcaga gacgctgaac tatctccgtt
    71941 ctcaggaagt ggggctcaag attatctctg gtgacaatcc agttacggta tccagcattg
    72001 cccagaaggc tggttttgcg gactatcaca gctatgtcga ttgttcaaaa atcacggatg
    72061 aggaattgat tgctctggcg gaggagacag cgattttcgg acgtgtttcc cctcatcaaa
    72121 agaaactcat tatccaaacg ctgaaaaaag cgggtcatac aacagctatg actggggatg
    72181 gagttaatga tatcctggct cttcgtgagg cggattgttc tatcgtaatg gcggagggag
    72241 acccggcaac ccgtcagatt gccaacctgg ttctcttgaa ctcagacttt aatgatgttc
    72301 ctgagattct ttttgaaggt cgtcgtgtgg tcaataacat tgcccacatc gctccgattt
    72361 tcttgataaa gaccatctac tcattcttgc tcgcagttat ctgcatcgcc agtgctttac
    72421 taggtcggtc tgaatggatc ttgattttcc ccttcattcc aatccagatt accatgattg
    72481 accagtttgt ggaaggtttc ccaccattcg ttttgacttt tgagcgaaat atcaaacctg
    72541 tcgagccaaa cttcctcaga agatccatgc ttcgtgccct accaagtgcc ctcatggtcg
    72601 tgtttagcgt tctttttgtg aaaatctttg gaacgagtca aggttggtct gagttagaaa
    72661 tctcaactct cctctattat ctcttggggt caattggttt cttatccgta tttagagcct
    72721 gcatgccatt cactctatgg cgagtcctct tgattgtttg gtcagtagga ggcttcctag
    72781 ccacagctct cttcccaaga attcaaaaac tgcttgaaat tgcaacctta acaggacaaa
    72841 cattacctgt ttatggtgtc atgatgttgg tctttaccgt gattttcatc ctgaccagtc
    72901 gctatcaagc cagaaaataa agaaaggctg caatctgtgg attgcggttt ttttaggtac
    72961 aagattgcca gccgaaatgt ggtataataa gaggtaatag agttttggaa agtgagagaa
    73021 gatgatttca aagagattag aattggtagc ttcctttgtg tcacaggggg ctattttact
    73081 agatgtggga agtgaccatg cttatctgcc tatcgagttg gttgagagag gccaaatcaa
    73141 aagcgctatt gcaggtgagg tggtggaagg tccctatcag tctgcggtta aaaatgttga
    73201 ggctcacggc ctaaaggaga aaatccaagt ccgtttagcc aatggcttgg cagcttttga
    73261 agagattgac caagtgtctg tcattaccat tgctggcatg ggtggttgtt tgattgctag
    73321 gattttagaa gaaggtttgg ggaagttagc taatgtagag cgtttgatcc tccagcccaa
    73381 taatcgtgaa gacgacttgc gtatctggct acagaatcat ggattccaga ttgtagcaga
    73441 aagcatctta gaagaagctg gcaagtttta cgagattttg gtggtggaag caggacaaat
    73501 gaagctatca gccagtgatg ttcgctttgg tcccttcttg tccaaagaag tcagtccagt
    73561 atttgtccaa aaatggcaaa aagaagctga gaagctagag ttcgccctcg gacaaatccc
    73621 agaaaaaaat ctggaagaac gtcaagttct agtagataag attcaagcta tcaaggaggt
    73681 gccccatgtt agcaagtgaa gtgatccaag cttatgaagc cttttgccct caggaatttt
    73741 ctatggaggg agacagccgt ggtctgcaaa ttggcacttt agacaagggt atccaaaggg
    73801 tcatggttgc cctcgatatt cgtgaagaga cagtggcaga ggccattgaa aagggtgtgg
    73861 acttgattat cgtcaagcac gcgcctatct ttcgtcctat caaggacttg cttgccagcc
    73921 gtccgcaaaa tcagatttac atcgacctga ttaagcatga tatcgcagtt tatgtcagcc
    73981 ataccaatat tgatatcgtt gaaaatgggc tcaatgactg gttttgtcag atgctaggaa
    74041 tcgaggagac gacttatctg caggaaacag gtccagaacg tggaattgga cgtattggga
    74101 atattcagcc tcagacattt tgggaattgg cccaacaggt caagcaagtc tttgacctag
    74161 atagccttcg aatggtgcat tatcaagaga atgatttgca gaagcctatt tcaagagtag
    74221 caatttgtgg tggaagcggg cagtctttct ataaggatgc tttggcaaag ggggcagatg
    74281 tctatatcac tggtgatatc tactaccata ctgctcagga tatgctgtct gatggcttgt
    74341 tagcattgga tccaggtcac tatatcgaag tgctttttgt ggaaaaaatc gcagcactcc
    74401 ttactcaatg gaaagagaaa aaaggctggg aactagagat tttacctagt caagcatcga
    74461 ccaatccttt ccgtcatatc tagttagaaa gtgaagacaa tgaaaaaagt tgccattatt
    74521 ggagcaggaa ttgtgggagc aacagctgcc tactacctct cgagagaaag tgacctagag
    74581 gtgaccgttt ttgaccatga gcaaggtcaa gccaccaagg ctgcagcagg aattatcagt
    74641 ccttggtttt ccaaacgccg taataaagcc tggtacaaga tggcgcgctt gggggctgat
    74701 ttttatgtgg atttattagc tgatttagag aaatcaggac aaaaaatcga cttttaccag
    74761 cgttcgggag tctttctctt gaaaaaggat gaatccaagt tggaagaact ttatcaactg
    74821 gccctccagc gcagagaaga atctcccttg atagggcaat tagctattct ggaccaagcc
    74881 tcagctaatg aattattccc tggtttgcag ggatttgacc gcctgctcta tgcttctggt
    74941 ggagcgagag tagatggcca cctcttagtg actcgtttgc tggaagccag tcaggtcaag
    75001 ctggtcaaag aaaaagtgac tctgacaccg ttagcatcag gctaccagat tggtgaagag
    75061 gagtttgagc aggttatttt ggcgacggga gcttggttgg gggacatgtt agaacccttg
    75121 ggttatgaag tagatgttcg tcctcaaaaa ggacaactac gagattatca gctggtccaa
    75181 gacatggaag cttaccctgt tgtcatgcca gaaggggagt gggatttgat tccttttgca
    75241 ggtgggaaat tgtccttagg cgctacccac gaaaatgaca tgggatttga tttgacggta
    75301 gatgaaacct tgctccaaca aatggaggag gccaccttga ctcactatct gattttggct
    75361 gaagctactt caaaatctga gcgtgtggga atccgtgcct ataccagtga tttctctccc
    75421 ttctttgggc aggtgccaga attggcaggt gtctatgcag ccagtggact aggttcatca
    75481 ggcctcacaa ctggtcctat cattggttac catctagccc aactgatcca agacaaggag
    75541 ttgaccttgg accctctaaa ttacccaatt gaaaactatg tcaaacgagt aaaaagcgaa
    75601 taatactcaa tgaaaatcaa agaacaaact aggaaactag ccgcgggtta ctcaaagcac
    75661 tgctttgagg ttgtgtatag aactgacgaa gtcagtaacc atacccatgg caaggcgacg
    75721 ttgacgtggt ttgaattgga ttttcgaaga gtataagcat tttactgaaa ttttatcagg
    75781 tagtttagga tggcaaatga cattccctgt caaaaatggt aaaataagaa aaaataatct
    75841 gagaatcgag gaaaaaagat gcaagaaaag attttggtaa ctggtggtgc cggttttatt
    75901 ggaacccaca ctgttattga attgatccaa gcaggccatc aagttgttgt ggtggataat
    75961 cttgtcaata gcaatcgtaa gagtttagaa gttgttgaaa gaatcacagg agttgagatt
    76021 cctttctatg aggcagatat tcgtgacaca gctaccctca gagatatttt caagcaggaa
    76081 gaaccgactg gtgtcattca ctttgctggt ttgaaggctg ttggcgaatc aacacgtatc
    76141 cctcttgcct actatgacaa caatatcgct ggaactgtca gccttttgaa agccatggaa
    76201 gaaaacaact gtaaaaacat catcttcagt tcttctgcga cagtttacgg ggatccgcac
    76261 acagtgccca tcttggaaga tttcccactt tcagtgacca acccatacgg tcgtaccaag
    76321 ctcatgctag aggaaatttt gaccgatatt tacaaagcag actcagaatg gaatgttgtc
    76381 ttgcttcgtt actttaaccc aatcggagcc catgagagtg gtgatttggg agaaaatcca
    76441 aacggtattc caaacaatct cttgccatat gtgactcaag tagccgttgg aaaattagag
    76501 caagtgcaag tgtttggaga cgattacgat acggaagatg gaacaggtgt tcgtgactat
    76561 atccacgttg tcgatttggc taagggtcac gttgcagctt tgaaaaaaat ccaaaaaggt
    76621 tcaggactaa acgtttataa ccttggaact ggtaaaggtt actcagttct tgaaattatc
    76681 caaaacatgg aaaaagcggt gggacgtcct attccttacc gcatcgtaga acgtcgccca
    76741 ggtgatatcg ctgcctgcta ctcagaccca gcaaaagcta aagcagaact cggttgggaa
    76801 gcagaactcg acatcaccca aatgtgtgaa gacgcatggc gttggcaaag caagcatcca
    76861 aatggatttg aagactaaga tgatgatttc aatcatcgtc ccttgtttaa acgaagagga
    76921 agtacttcct cttttttatc aggctctgga agctttactt ccagatttgg aaacagaaat
    76981 cgagtatgtc tttgtcgatg atggatcaag tgatgggacc ttggaactct taaaggccta
    77041 tcgggagcaa aatccggcag tccattatat ttctttctct cgaaattttg gcaaagaagc
    77101 agccctttat gcaggcttgc aatatgcgac aggagatttg gtggtggtga tggatgcaga
    77161 cctccaagat cctcctagta tgttgtttga gatgaaaaat gtactagaca aaaatgtaga
    77221 cttggactgc gttgggacac ggagaactag tcgggaggga gaacccttct ttcgcagttt
    77281 ctgtgctgtt ctcttttatc gcctcatgca aaaaatcagc ccagtagctc tgccgtcggg
    77341 tgtccgtgat tttcgtatga tgagaaggtc tgtagtcgat gccattttaa gcttgaccga
    77401 gtccaatcgt ttttcaaagg ggctcttcgc ctgggtgggt ttcaaaacct actatttgga
    77461 ctatccaaat gtcgaaaggc aggctggcaa gacaagttgg agttttaggc aactcttttt
    77521 ctactccatt gaagggatta ttaatttttc agattttccc ttgattatag cctttgtagc
    77581 tggtctccta tcttgttttc tttctctgct gatgaccttt tttgttgtgg ttcggaccct
    77641 cattttgggc aatccgacat ctggttggac ctctctgatg gctgttattc tctttcttgg
    77701 aggcattcaa ctcttgacca ttgggattct cggcaagtat atcagtaaga tttatttaga
    77761 gactaaaaaa agaccacttt atcttatcaa agaaaaaagt gaccttcctg attttacaga
    77821 aaaaaataaa gtgaaaagac tataatttta catggaaatg tgctaaacta gagggagtgg
    77881 attatcgcca ttgatttagg cttcctggtt tccaatcagg gcgcgagttg ggcaattttt
    77941 aacagcctct aagacatcct gactaggaga aatttctttt tccagttggt cagggtcatc
    78001 gtaaaaacgc acgattccat tatcgtggta atcaaataaa tcagaataag tttggcaaag
    78061 cccacaggcg atacatcgtt caggtataag tgtgattttc atgttcatat ttatattgta
    78121 ataagaaaag taaaaaaaaa caaggagtaa ggtatggcaa aagaaccgtg gcaagaagat
    78181 atctatgatc aagaagaatc aagagcagag cgtcggcatc gaaaccacgg aggggctgat
    78241 aggatggcta atcgtatttt gacgatccta gctagtattt tctttgtaat tgtggtggtg
    78301 atggtcatcg ttctcatcta tctatcatcg ggggggagta atcgcacagc agccttaaaa
    78361 gactttcatg attctgatgc aagtgtagta caaatctcat cttcaagcag ttctcagcct
    78421 gagcagagtt cagagccaga atctacttct agtagttcag aagaagctgc taatcctgaa
    78481 ggaacgatta aagttctcgc aggagaaggg gaagcagcta ttgccgctcg tgcaggaatc
    78541 tccattgctc agttagaggc cttgaatcct gggcacatgg ctacaggatc ttggtttgct
    78601 aatccaggtg atgttataaa aataaaatag gagccgatat gaaaacaatt caaattgcta
    78661 ttgatggtcc tgcttccagc ggtaagagta cggtcgcaaa gattattgct aaggattttg
    78721 gattcaccta ccttgataca ggagctatgt atcgtgcagc gacctatatg gctcttaaga
    78781 accaattagt agttgaagaa gtcgaagccc ttctagcctt gttggaccag catccaatca
    78841 gctttggacg ttcagaaact ggagaccagc ttgtttttgt aggagatgtg gatattaccc
    78901 atcctatccg tgaaaatgaa gtgaccaatc atgtttctgc tattgcagca attcctgaag
    78961 tgcgtgagaa actggtttct ctccaacaag aaattgccca gcaaggcggg attgtcatgg
    79021 atggtcgcga tattggaact gttgtattgc cacaagcaga attgaaaatt ttcctagtag
    79081 cttctgttga tgagagagca gagcgtcgtt acaaggaaaa tattgccaag ggaattgaaa
    79141 cagaccttga aaccctaaaa aaggaaattg ctgcgcgtga ctacaaggat agtcatcgtg
    79201 agacttctcc tctcaaacaa gcagaggatg ctgtctacct tgatacaact ggtttgaaca
    79261 ttcaagaagt agttgaaaaa atcaaagcag aagctgaaaa aagaatgtaa atgtagaaaa
    79321 gccgatagat tgatatcggt ttttttctaa atttgtcaaa atgctgattt tagggtataa
    79381 tagttgctgt tcgagaaatt ttgattttca aagaatagtg aatgatgata aggagaaacc
    79441 atgaacaatt taccaaattg tccaaaatgt aactcagagt atgtctacga agacggtgcc
    79501 ctactggttt gcccagagtg tgctcatgag tggaatcctg ctgaagttgc agaagtagaa
    79561 gaaggtcttg tcgctatcga tgccaacgga aataaattgg ctgatggtga tacagtaact
    79621 ctcatcaagg acttgaaagt aaaaggtgcg ccaaaagatt tgaaacaagg gacgcgcgtg
    79681 aaaaatatcc gcatcgtaga aggcgaccac aatatcgact gtaagattga tggttttggt
    79741 gccatgaaac ttaaatcaga gtttgtgagg aagatttaag catgtcaaaa cactataaac
    79801 ttgtatttta tagccgtatc ttcttgtttc tagcggcttt tacgggagtt tatcttgaaa
    79861 ttactaggca tggtggtttt gggatgcttc tctattacac ggttctgtcc aacctcttgg
    79921 taactatttt taccctttat cttctaaagg ttatgagccg tgtaggtgaa aattggcaaa
    79981 ggccaagtct cttgcgctta aaaggtgggg tcaccatgag tatcatgatt acctgtgtga
    80041 tttaccattt cctcttggcg cccattgcga ctaatttcta taccctagaa aatttccttt
    80101 gccactatat cgttcccatc tggtttttag cggataccct cttttttgac aaacagggtc
    80161 aatacaagat ttgggatcca gcagtgtgga ccattttacc ctttctgtat atgatgtttg
    80221 ctctttttaa tggcttggtt ctaaaactca atattccaaa tgccaaggat aatcctttcc
    80281 cttacttctt tttgaatgtg aacaagggtt ggaatgttgt gtttaagtgg tgtctgatta
    80341 tctttgttgc ctatatggta gcaggattta ttttctactt tatcaagcaa atcaagagaa
    80401 agtcatccta atactcttcg aaaatctctt caaaccacgt cagtttccat ctgcaacctc
    80461 aaaacactgt tttgaacaac ctgcggctag cttcctagtt tgctctttga ttttcattga
    80521 gtataagata caagggattc attttcgaat ttaagaagga gtctacaaac caatgaggct
    80581 tcttcttttc ttgcttattt gataactatc aaaaaagtag aagattaaga gaaatataga
    80641 aagagatttc atgaaacaat ttttagaacg ggccagcatt ttggctctct ccctcgtttt
    80701 gattacctcc ttttccattt cgagtgccct accagccatg tttgactatt atcagggtta
    80761 ttctaaggaa caaattgagc tcttggtgag cttgccttcc tttggaatca tgatgatgtt
    80821 actgctaaat ggtttcttag aaaaaatatt tcctgagcgc ttacagatta gtttgggctt
    80881 gctgatttta tcattgagcg gtacagctcc cttctggtac caagcctatc cctttgtctt
    80941 tggaacacgg cttctctttg gtttgggtct tgggatgatc aatgccaagg ccatttctat
    81001 tatcagtgaa cgctaccaag gaaaaaggcg aattcagatg ttagggctac gcgcttctgc
    81061 agaggtcgtt ggagcttctc tcattacctt ggccgtcggt cagttgttgg cctttggttg
    81121 gacagctatc tttctagcct atagtgctgg atttttggtg ctgccccttt atctgctctt
    81181 tgtcccttat ggaaaatcaa agaaagaagt caagaaaaga gcgaaggaag caagtcgttt
    81241 aactcgagaa atgaaaggct tgatttttac cttagctatc gaagcggcag ttgtagtttg
    81301 taccaataca gctattacca tccgtattcc aagtttgatg gtggaaagag gattggggga
    81361 tgcccagtta tctagttttg ttcttagtat catgcagttg atcgggattg tggctggggt
    81421 gagtttttct ttcttgattt ctatctttaa agagaaactg ctcctctggt ctggtattac
    81481 ctttggcttg gggcaaatcg tgattgcctt gtcttcatcc ttgtgggtgg tagtagcagg
    81541 aagtgttctg gctggatttg cctatagtgt agtcttgacg acggtctttc aacttgtctc
    81601 tgaacgaatt ccagctaaac tcctcaatca agcaacttca tttgctgtat taggctgtag
    81661 tttcggagcc tttacgaccc cattcgttct aggtgcaatt ggcttactaa ctcacaatgg
    81721 gatgttggtc tttagtatct taggaggttg gttgattgta atctctatct ttgtcatgta
    81781 cctacttcag aagagagctt aggattgatt cctaagtttt tcttttgata ctcaatgaaa
    81841 atcaaagagc atagttgatt gagtttggaa tagtacgctg tagctgctaa aatatttcta
    81901 gaaattaatt tgactttcct aatagagttg ttcatatctt atttcaatct actatagaaa
    81961 gctagccgca ggttgctcaa aatagtgtgt tgaggttgca gatggaaact gacgtggttt
    82021 gaagagattt tcaagagtat aagattttta tacccataca atatttgttt taggtccttg
    82081 tttacagact aatttcttga taaaatagag gttatgacga gatataaagc aactatttcc
    82141 tatgatggtt atgcctttgc tggctttcag cgccagcctc atgcgcgtag cgttcaggaa
    82201 gaaattgaaa aaaccttgac cagattaaat aaagggcaaa ccattactgt tcacggtgct
    82261 ggtaggacag atagtggggt tcatgccctg ggacaggtca ttcattttga cctgccttat
    82321 cagatggatg aggagaaact ccgttttgcc ttggataccc agtctcctga agatattgat
    82381 gtgatttcga ttgagcttgt ggcagctgat tttcattgcc gttatgccaa gcatagcaag
    82441 acctatgagt ttattgtgga tagaggacgt cccaaaaatc cgatgcgccg tcactatgcc
    82501 acccactttc cctacccact cgatgtggaa cgaatgcaga ttgcaatcaa aaagctagag
    82561 ggaacccatg attttaccgg ttttacagcc tctgggacta gtgtagagga taaggttcgc
    82621 accatcacag aagctagttt aatagtcgat gagacaggac aatttttgac ctttaccttt
    82681 tcaggaaatg gtttcttgta taaacagatt cgcaatatgg tggggactct tctcaaaatc
    82741 ggtaacaacc gcatgccagt agagcagatt gatctcatct tggagaagaa ggacaggcaa
    82801 cttgcaggtc ccactgcagc accaaatggt ttgtatttaa aggagattcg ttatgaagaa
    82861 taatcgtatt ttagcacttt ctggaaatga tatttttagt ggtggtggac tgtcagctga
    82921 tttggctacc tataccttga acggcttgca tgggtttgta gcagtgactt gtttgacagc
    82981 cttgacagaa aaaggatttg aagtctttcc aactgatgat accatttttc aacatgaatt
    83041 agatagcttg cgtgatgtgg aatttggggg aattaagatt ggtcttctcc ctactgtcag
    83101 tgtggctgag aaggccttgg actttatcaa acaacgccca ggaatacctg tggtgttgga
    83161 tcctgtcttg gtctgcaagg aaacgcatga tgtagctgtc agtgagctct gccaagagtt
    83221 gattcgcttt ttcccttatg tcagtgtgat tacgcctaat ctcccagaag cagaattatt
    83281 atccggtcag gaaattaaaa ccttggaaga catgaaaact gcagcgcaga aattgcatga
    83341 tttaggagcg ccagcagtca ttatcaaggg aggcaatcgt cttagtcagg acaaggctgt
    83401 ggatgtcttt tatgatggac agacctttac tatcctagaa aatccagtta tccaaggcca
    83461 aaatgctggt gcaggttgta cctttgcctc tagcattgcc agtcacttga ttaaaggtga
    83521 taaacttttg ccagcagtag aaagctctaa ggctttcgtt tatcgtgcta ttgcacaagc
    83581 agatcagtat ggagtaagac aatatgaagc aaacaaaaac aactaaaatc gcccttgtat
    83641 ccctattaac cgccctttct gtggttctag gttatttctt aaaaatccca acacctacag
    83701 gaattctaac tcttttagat gctggtgtct tctttgcggc cttttacttt ggtagtcgtg
    83761 aaggagcggt agtcggagga ctagcaagtt tcttgattga cctcttatca ggctaccctc
    83821 agtggatgtt ctttagcttg gtcaaccatg gcttgcaggg atttttcgca ggatttaaag
    83881 gaaaaagtca gtggttaggc cttattttag caactattgc catggtagga ggctacgcct
    83941 tgggttctac tttgatgaat gactgggcag cagccctccc agaaattcta ccaaatttta
    84001 tgcaaaatat ggtagggatg attgtaggat ttattcttag tcaaagtatc aagaagatta
    84061 agtaatactc ttcgaaaatc tcttcaaacc acgtcagctt ccatctgcaa cctcaaaaca
    84121 ctgttttgag cagcctgagg ctagctttct agtttgcact ttgattttca ttgagtataa
    84181 agaggttgag taaaaagtat ttcaaataag aaaaacgcat agtataggat gttgaaatga
    84241 tgaactgccc cccaaaagtt agacagaaaa aatctaactt ttggggtgtt ttattatgaa
    84301 actaacttat gatgataaag ttcagatcta tgaacttaga aaacaaggat atagcttaga
    84361 gaagctttca aataaatttg ggataaacaa ttctaatctt aggtacatga ttaaattgat
    84421 tgatcgttac ggaatagagt tcgtcaaaaa aggaaaaaat cgttactatt ctcctgttta
    84481 aaacaagaaa tgattaataa agtctgacat gaaggct
//
LOCUS       DBERPV010000005        81020 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.05, whole genome shotgun sequence.
ACCESSION   DBERPV010000005 DBERPV010000000
VERSION     DBERPV010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 81020)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 81020)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..81020
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.05"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            156..320
                     /locus_tag="ACL8C7_000458"
     CDS             156..320
                     /locus_tag="ACL8C7_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGS1394718.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            404..970
                     /gene="amaP"
                     /locus_tag="ACL8C7_000459"
     CDS             404..970
                     /gene="amaP"
                     /locus_tag="ACL8C7_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HGS1394719.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            982..1152
                     /locus_tag="ACL8C7_000460"
     CDS             982..1152
                     /locus_tag="ACL8C7_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HGS1394720.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1191..1799
                     /locus_tag="ACL8C7_000461"
     CDS             1191..1799
                     /locus_tag="ACL8C7_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGS1394721.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1830..2033
                     /locus_tag="ACL8C7_000462"
     CDS             1830..2033
                     /locus_tag="ACL8C7_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGS1394722.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2143..2382)
                     /locus_tag="ACL8C7_000463"
     CDS             complement(2143..2382)
                     /locus_tag="ACL8C7_000463"
                     /inference="COORDINATES: protein motif:HMM:NF025126.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS1394723.1"
                     /translation="MNERYQCLKTKEYQALLSSKGRQIFAKRKIDMKSVFGQIKVCLG
                     YKRCHLRGKRQVRIDMGFILMANNLLKYNKRKRQN"
     gene            2660..2905
                     /locus_tag="ACL8C7_000464"
     CDS             2660..2905
                     /locus_tag="ACL8C7_000464"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGS1394724.1"
                     /translation="MAESIQGWLAQFLVNLFKSITFDCGKEFSKWKDISNHHDSESFF
                     ANLGCPRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            complement(3183..3953)
                     /locus_tag="ACL8C7_000465"
     CDS             complement(3183..3953)
                     /locus_tag="ACL8C7_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HGS1394725.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(3968..4816)
                     /locus_tag="ACL8C7_000466"
     CDS             complement(3968..4816)
                     /locus_tag="ACL8C7_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HGS1394726.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVSNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(4813..6288)
                     /locus_tag="ACL8C7_000467"
     CDS             complement(4813..6288)
                     /locus_tag="ACL8C7_000467"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HGS1394727.1"
                     /translation="MVQTKQPNIILIVVDQMRADVLSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(6611..7966)
                     /locus_tag="ACL8C7_000468"
     CDS             complement(6611..7966)
                     /locus_tag="ACL8C7_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGS1394728.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDKILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(7976..8293)
                     /locus_tag="ACL8C7_000469"
     CDS             complement(7976..8293)
                     /locus_tag="ACL8C7_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGS1394729.1"
                     /translation="MNESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANQRLAD
                     ANAALLQAHKAQTEMLTREAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYKRF
                     EKN"
     gene            complement(8310..8627)
                     /locus_tag="ACL8C7_000470"
     CDS             complement(8310..8627)
                     /locus_tag="ACL8C7_000470"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS1394730.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(8643..9539)
                     /locus_tag="ACL8C7_000471"
     CDS             complement(8643..9539)
                     /locus_tag="ACL8C7_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HGS1394731.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(9542..10804)
                     /locus_tag="ACL8C7_000472"
     CDS             complement(9542..10804)
                     /locus_tag="ACL8C7_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGS1394732.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            11084..12262
                     /locus_tag="ACL8C7_000473"
     CDS             11084..12262
                     /locus_tag="ACL8C7_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HGS1394733.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDNYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(12490..12936)
                     /locus_tag="ACL8C7_000474"
     CDS             complement(12490..12936)
                     /locus_tag="ACL8C7_000474"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1394734.1"
                     /translation="MTIRFEEKVSTENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGFIQKIRLEDSNLHIGRFFITPQKQEQGLGSKALRKFVSLAFE
                     NEDIDSISLNVFEANQIAQNLYQKEGFEIVQMVEAPVRKYSRLKLE"
     gene            13006..13665
                     /locus_tag="ACL8C7_000475"
     CDS             13006..13665
                     /locus_tag="ACL8C7_000475"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HGS1394735.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELSLGLLFLLCSWGWLSLGQVVLITAG
                     LTLGIYDFHHQKYPLLVWMTFQLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            complement(13717..14868)
                     /locus_tag="ACL8C7_000476"
     CDS             complement(13717..14868)
                     /locus_tag="ACL8C7_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS1394736.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(14883..15614)
                     /locus_tag="ACL8C7_000477"
     CDS             complement(14883..15614)
                     /locus_tag="ACL8C7_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394737.1"
                     /translation="MLNQDLFDSLEAQRIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            15843..15944
                     /locus_tag="ACL8C7_000478"
                     /pseudo
     CDS             15843..15944
                     /locus_tag="ACL8C7_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            complement(15916..16692)
                     /gene="trpA"
                     /locus_tag="ACL8C7_000479"
     CDS             complement(15916..16692)
                     /gene="trpA"
                     /locus_tag="ACL8C7_000479"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HGS1394738.1"
                     /translation="MPKTLTEKLNAIKATGKGIFVPYIMAGDHEKGLDGLGETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQVLVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(16685..17908)
                     /gene="trpB"
                     /locus_tag="ACL8C7_000480"
     CDS             complement(16685..17908)
                     /gene="trpB"
                     /locus_tag="ACL8C7_000480"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HGS1394739.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGRDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(17886..18485)
                     /locus_tag="ACL8C7_000481"
     CDS             complement(17886..18485)
                     /locus_tag="ACL8C7_000481"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HGS1394740.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLPQSFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKNGISRTK"
     gene            complement(18472..19239)
                     /gene="trpC"
                     /locus_tag="ACL8C7_000482"
     CDS             complement(18472..19239)
                     /gene="trpC"
                     /locus_tag="ACL8C7_000482"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004425 - indole-3-glycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006568 - tryptophan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HGS1394741.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            complement(19236..20240)
                     /gene="trpD"
                     /locus_tag="ACL8C7_000483"
     CDS             complement(19236..20240)
                     /gene="trpD"
                     /locus_tag="ACL8C7_000483"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004048 - anthranilate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HGS1394742.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(20251..20817)
                     /locus_tag="ACL8C7_000484"
     CDS             complement(20251..20817)
                     /locus_tag="ACL8C7_000484"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HGS1394743.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            complement(20814..22175)
                     /gene="trpE"
                     /locus_tag="ACL8C7_000485"
     CDS             complement(20814..22175)
                     /gene="trpE"
                     /locus_tag="ACL8C7_000485"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HGS1394744.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKTLATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            complement(22547..22708)
                     /locus_tag="ACL8C7_000486"
     CDS             complement(22547..22708)
                     /locus_tag="ACL8C7_000486"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394745.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVADRTDEVSNHTYDKATLTRFEEI
                     FEEYKGVPR"
     gene            complement(23316..24317)
                     /locus_tag="ACL8C7_000487"
     CDS             complement(23316..24317)
                     /locus_tag="ACL8C7_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS1394746.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            complement(24425..24793)
                     /locus_tag="ACL8C7_000488"
     CDS             complement(24425..24793)
                     /locus_tag="ACL8C7_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394747.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYIDRLLYVFINPTHFTEKVNLQFYGSFFSYEFICREVGN
                     ILKNKGVKCNLNFFEGEEYL"
     gene            complement(24889..25599)
                     /locus_tag="ACL8C7_000489"
     CDS             complement(24889..25599)
                     /locus_tag="ACL8C7_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HGS1394748.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            complement(25602..27293)
                     /locus_tag="ACL8C7_000490"
     CDS             complement(25602..27293)
                     /locus_tag="ACL8C7_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1394749.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDPNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            complement(27305..28315)
                     /locus_tag="ACL8C7_000491"
     CDS             complement(27305..28315)
                     /locus_tag="ACL8C7_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1394750.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGELFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARTLVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            complement(28419..29486)
                     /locus_tag="ACL8C7_000492"
     CDS             complement(28419..29486)
                     /locus_tag="ACL8C7_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGS1394751.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKNFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            complement(29511..30170)
                     /locus_tag="ACL8C7_000493"
     CDS             complement(29511..30170)
                     /locus_tag="ACL8C7_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HGS1394752.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            complement(30350..31360)
                     /gene="galE"
                     /locus_tag="ACL8C7_000494"
     CDS             complement(30350..31360)
                     /gene="galE"
                     /locus_tag="ACL8C7_000494"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGS1394753.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSKLVLDRI
                     EAITGIRPVFYELDVCDKQALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGIPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFE
                     SVNKIPIPYKIVPRRSGDVATCYANADKAYKELNWRTTKSIEDMCRDTWNWQSKNPNG
                     YN"
     gene            complement(31373..32848)
                     /gene="galT"
                     /locus_tag="ACL8C7_000495"
     CDS             complement(31373..32848)
                     /gene="galT"
                     /locus_tag="ACL8C7_000495"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HGS1394754.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGIDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYSYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFCFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVN
                     SVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            complement(32861..33502)
                     /locus_tag="ACL8C7_000496"
     CDS             complement(32861..33502)
                     /locus_tag="ACL8C7_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HGS1394755.1"
                     /translation="MLRLYLENEIIELSNNLETIWVSVLDKYEKLFEYLSNEERVELI
                     KEDLIINESVLNIDKKGYELICLQHPVSYDLRRIISVIKISTDIERIGDRIVEILKNL
                     QILQNNEILKKIISKIKILHEVIGLHMNRAISCYREEQSGCLDMVVIQKQNEIEELSI
                     NMEKKIMNYIFEDDGNVSEVISALDIIHHLDKIAHTTQAIYKWIMYRKYGNIN"
     gene            complement(33560..33772)
                     /locus_tag="ACL8C7_000497"
     CDS             complement(33560..33772)
                     /locus_tag="ACL8C7_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394756.1"
                     /translation="MDERFLDHAIINQIDVTSEQIVLMSDGFYEFYQNNQNKTFEELI
                     KMRFNSSAIDPIYGKKDDASILVIDV"
     gene            complement(33801..33944)
                     /locus_tag="ACL8C7_000498"
     CDS             complement(33801..33944)
                     /locus_tag="ACL8C7_000498"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394757.1"
                     /translation="MLVNEMEITDHRVDNLFEKGKNEIKDSIGTNSVLNKKNYFTKNQ
                     KII"
     gene            complement(34104..34400)
                     /locus_tag="ACL8C7_000499"
     CDS             complement(34104..34400)
                     /locus_tag="ACL8C7_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394758.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYKLTEYSKMK"
     gene            complement(34384..36510)
                     /gene="pfbA"
                     /locus_tag="ACL8C7_000500"
     CDS             complement(34384..36510)
                     /gene="pfbA"
                     /locus_tag="ACL8C7_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HGS1394759.1"
                     /translation="MKYFVPNEVFSIRKLKVGTCSVLLAISILGSQGILADEVVTSSS
                     PMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNSISSNGTIRSNS
                     QLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAVGDGIHDDRQAI
                     QDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILNGINIKNHPSIV
                     FMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLINSSGAFAIGNS
                     NNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQIISKESIQIEP
                     LTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTLSTQNPSNIKIL
                     NNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVNAYSYKNTKDLL
                     DLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVINNNSKETEQPNI
                     ELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYISFIKSNANGKE
                     PVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVIDSNQKNGEFNS
                     SKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVKQKLPKTGSNKI
                     MELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(37674..38900)
                     /locus_tag="ACL8C7_000501"
     CDS             complement(37674..38900)
                     /locus_tag="ACL8C7_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HGS1394760.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(38943..39635)
                     /locus_tag="ACL8C7_000502"
     CDS             complement(38943..39635)
                     /locus_tag="ACL8C7_000502"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGS1394761.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWFLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            complement(39808..41559)
                     /locus_tag="ACL8C7_000503"
     CDS             complement(39808..41559)
                     /locus_tag="ACL8C7_000503"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1394762.1"
                     /translation="MQNKQEQWTVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPLQENGQA
                     KVKEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMAYTL"
     gene            complement(41549..43294)
                     /locus_tag="ACL8C7_000504"
     CDS             complement(41549..43294)
                     /locus_tag="ACL8C7_000504"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1394763.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLVVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADLILVLQNGQIIERGRHEDLLALDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(43422..43952)
                     /locus_tag="ACL8C7_000505"
     CDS             complement(43422..43952)
                     /locus_tag="ACL8C7_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HGS1394764.1"
                     /translation="MTLNYIEILIKLVLTLKWLNNNVHFVKRLIDGKPTLLIKNGNID
                     PEACRSVGLSASDVALKLRSQGIFQMKQVKGAVQEQNGQLIVVQMGDENPKYPVVTDG
                     VIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYEKEKPGVLYSS
                     KISSNRVNVALPYVGY"
     gene            complement(43949..44405)
                     /locus_tag="ACL8C7_000506"
                     /pseudo
     CDS             complement(43949..44405)
                     /locus_tag="ACL8C7_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            44539..45366
                     /locus_tag="ACL8C7_000507"
     CDS             44539..45366
                     /locus_tag="ACL8C7_000507"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HGS1394765.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            45378..45473
                     /locus_tag="ACL8C7_000508"
                     /pseudo
     CDS             45378..45473
                     /locus_tag="ACL8C7_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
     gene            45521..45760
                     /locus_tag="ACL8C7_000509"
     CDS             45521..45760
                     /locus_tag="ACL8C7_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HGS1394766.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRLLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     regulatory      46143..46238
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            46638..47219
                     /locus_tag="ACL8C7_000510"
     CDS             46638..47219
                     /locus_tag="ACL8C7_000510"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HGS1394767.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            47219..48481
                     /locus_tag="ACL8C7_000511"
     CDS             47219..48481
                     /locus_tag="ACL8C7_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HGS1394768.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPLDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(48532..48993)
                     /locus_tag="ACL8C7_000512"
     CDS             complement(48532..48993)
                     /locus_tag="ACL8C7_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DpnD/PcfM family protein"
                     /protein_id="HGS1394769.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(48990..49754)
                     /locus_tag="ACL8C7_000513"
     CDS             complement(48990..49754)
                     /locus_tag="ACL8C7_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnI"
                     /protein_id="HGS1394770.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            complement(49935..50339)
                     /locus_tag="ACL8C7_000514"
     CDS             complement(49935..50339)
                     /locus_tag="ACL8C7_000514"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HGS1394771.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVSI"
     gene            complement(50409..51890)
                     /locus_tag="ACL8C7_000515"
     CDS             complement(50409..51890)
                     /locus_tag="ACL8C7_000515"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HGS1394772.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLSRVGEGVLEVETNL
                     DKLIDLKDQLVEETVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ISAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGILLD"
     gene            complement(51909..53087)
                     /locus_tag="ACL8C7_000516"
     CDS             complement(51909..53087)
                     /locus_tag="ACL8C7_000516"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HGS1394773.1"
                     /translation="MAQHLTTEALRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELNEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLERDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            53252..54259
                     /gene="galR"
                     /locus_tag="ACL8C7_000517"
     CDS             53252..54259
                     /gene="galR"
                     /locus_tag="ACL8C7_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HGS1394774.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(54305..55342)
                     /locus_tag="ACL8C7_000518"
     CDS             complement(54305..55342)
                     /locus_tag="ACL8C7_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HGS1394775.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKVVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(55343..55696)
                     /gene="nmlR"
                     /locus_tag="ACL8C7_000519"
     CDS             complement(55343..55696)
                     /gene="nmlR"
                     /locus_tag="ACL8C7_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stress response transcriptional regulator NmlR"
                     /protein_id="HGS1394776.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(55940..56830)
                     /gene="czcD"
                     /locus_tag="ACL8C7_000520"
     CDS             complement(55940..56830)
                     /gene="czcD"
                     /locus_tag="ACL8C7_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter
                     CzcD"
                     /protein_id="HGS1394777.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGIFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            56963..57499
                     /gene="sczA"
                     /locus_tag="ACL8C7_000521"
     CDS             56963..57499
                     /gene="sczA"
                     /locus_tag="ACL8C7_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator SczA"
                     /protein_id="HGS1394778.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLQRELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(57666..58472)
                     /gene="pnuC"
                     /locus_tag="ACL8C7_000522"
     CDS             complement(57666..58472)
                     /gene="pnuC"
                     /locus_tag="ACL8C7_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HGS1394779.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSETMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(58817..60337)
                     /locus_tag="ACL8C7_000523"
     CDS             complement(58817..60337)
                     /locus_tag="ACL8C7_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HGS1394780.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVTV
                     LLGLSYSPALLVQKEKENVIIAGKIGPEPEILANMYKLLIEENTSLTATVKPNFGKTT
                     FLYEALKSGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVSTLEPALRYQAIQSGEIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(60330..61058)
                     /locus_tag="ACL8C7_000524"
     CDS             complement(60330..61058)
                     /locus_tag="ACL8C7_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS1394781.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            complement(61073..61837)
                     /locus_tag="ACL8C7_000525"
     CDS             complement(61073..61837)
                     /locus_tag="ACL8C7_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HGS1394782.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHDIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(61841..62284)
                     /locus_tag="ACL8C7_000526"
     CDS             complement(61841..62284)
                     /locus_tag="ACL8C7_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGS1394783.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(62966..63262)
                     /locus_tag="ACL8C7_000527"
     CDS             complement(62966..63262)
                     /locus_tag="ACL8C7_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGS1394784.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETAKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(63284..64348)
                     /gene="pepA"
                     /locus_tag="ACL8C7_000528"
     CDS             complement(63284..64348)
                     /gene="pepA"
                     /locus_tag="ACL8C7_000528"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HGS1394785.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            64749..65450
                     /gene="galE"
                     /locus_tag="ACL8C7_000529"
     CDS             64749..65450
                     /gene="galE"
                     /locus_tag="ACL8C7_000529"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGS1394786.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            65466..65576
                     /locus_tag="ACL8C7_000530"
     CDS             65466..65576
                     /locus_tag="ACL8C7_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HGS1394787.1"
                     /translation="MNYLFQEDSSSQIFNLGTKKGYTIKEIFKTAEELLN"
     gene            65873..66832
                     /locus_tag="ACL8C7_000531"
     CDS             65873..66832
                     /locus_tag="ACL8C7_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1394788.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFISSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            66822..67778
                     /locus_tag="ACL8C7_000532"
     CDS             66822..67778
                     /locus_tag="ACL8C7_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HGS1394789.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            67775..68527
                     /locus_tag="ACL8C7_000533"
     CDS             67775..68527
                     /locus_tag="ACL8C7_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1394790.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            68623..69588
                     /locus_tag="ACL8C7_000534"
     CDS             68623..69588
                     /locus_tag="ACL8C7_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS1394791.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEITI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETSTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDTQKALK"
     gene            complement(69813..70055)
                     /gene="yidD"
                     /locus_tag="ACL8C7_000535"
     CDS             complement(69813..70055)
                     /gene="yidD"
                     /locus_tag="ACL8C7_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HGS1394792.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(70055..70777)
                     /locus_tag="ACL8C7_000536"
     CDS             complement(70055..70777)
                     /locus_tag="ACL8C7_000536"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGS1394793.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVTNKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(70764..71333)
                     /gene="scpB"
                     /locus_tag="ACL8C7_000537"
     CDS             complement(70764..71333)
                     /gene="scpB"
                     /locus_tag="ACL8C7_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HGS1394794.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(71352..72080)
                     /locus_tag="ACL8C7_000538"
     CDS             complement(71352..72080)
                     /locus_tag="ACL8C7_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HGS1394795.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(72080..72814)
                     /gene="xerD"
                     /locus_tag="ACL8C7_000539"
     CDS             complement(72080..72814)
                     /gene="xerD"
                     /locus_tag="ACL8C7_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HGS1394796.1"
                     /translation="MRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETSLK
                     IYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEILYL
                     DSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVTIP
                     TALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFILRQ
                     IENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(72811..73272)
                     /gene="cbpB"
                     /locus_tag="ACL8C7_000540"
     CDS             complement(72811..73272)
                     /gene="cbpB"
                     /locus_tag="ACL8C7_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HGS1394797.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(73269..73790)
                     /locus_tag="ACL8C7_000541"
     CDS             complement(73269..73790)
                     /locus_tag="ACL8C7_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGS1394798.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(73766..74737)
                     /locus_tag="ACL8C7_000542"
     CDS             complement(73766..74737)
                     /locus_tag="ACL8C7_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009143 - nucleoside triphosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HGS1394799.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(74734..75528)
                     /gene="racE"
                     /locus_tag="ACL8C7_000543"
     CDS             complement(74734..75528)
                     /gene="racE"
                     /locus_tag="ACL8C7_000543"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HGS1394800.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTRQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRKKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            complement(75735..75983)
                     /locus_tag="ACL8C7_000544"
     CDS             complement(75735..75983)
                     /locus_tag="ACL8C7_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HGS1394801.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(76239..77864)
                     /gene="treC"
                     /locus_tag="ACL8C7_000545"
     CDS             complement(76239..77864)
                     /gene="treC"
                     /locus_tag="ACL8C7_000545"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HGS1394802.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(78042..80009)
                     /gene="treP"
                     /locus_tag="ACL8C7_000546"
     CDS             complement(78042..80009)
                     /gene="treP"
                     /locus_tag="ACL8C7_000546"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HGS1394803.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTVTIPGTYPTTIQAGASLMVATRI"
     gene            80194..80904
                     /gene="treR"
                     /locus_tag="ACL8C7_000547"
     CDS             80194..80904
                     /gene="treR"
                     /locus_tag="ACL8C7_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HGS1394804.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
BASE COUNT        24588 a        17727 c        14069 g        24636 t
ORIGIN      
        1 tgacttttct atattaaagt tatataatag taataatcaa agaaattgat tttttgatat
       61 taaaataaaa aaggagggta ggcagtgttg tgatcaatta ttgctggagg tcttattggt
      121 ctcttggcag gtaaaatcac taaaaaagta gttctatggg aatcatcgca aatgtattcg
      181 ctggtttagt cggggcatat gcaggacaat ctcttttagg tagttggggt ccatcaatcg
      241 ctggaatggc tttgctccca tctattgtag gtgcagcgat tgtgattact gtagtgtcat
      301 tctttacagg tagaaagtaa acttttcgcc agtaaagtta gcaaactatt tttaaatcaa
      361 tgacgggaaa aatagtttaa atgttaaatc gaaaggattg tatatgtcaa aagcaaagaa
      421 aatatgtttc attattttct gtattttaat cttgacaatt ttccttcctg ttttgataga
      481 ttatcatcaa gttagtgatc taggtattca tctacttagc tggagacaga actccgtagt
      541 tgaattctat cttgctagat atgtcttttg ggggacagtg gttctatcaa ctttagtttt
      601 attatccatt ttagttgtga tgttttatcc taaacgttac ttggaaatcc aacttgaaac
      661 taaaaacgat acattaaaat taaagaattc ggcaatcgaa ggttttgtta gaagtttggt
      721 gagtgatcat agattgatca agaacccaac tgttcatgta aatttacgaa aaaataaatg
      781 tttcgttcat gtagaaggta aaattcttcc ttcagacaac atcgctgaca gatgccaaat
      841 aattcaaaat gaaataacta atggattgaa gcagtttttt ggtattgagc gtcaagtaaa
      901 acttgaagtt gcagtaaaaa attaccaacc aaaacctcaa aacaaaaaga ctgttagtcg
      961 tgtgaagtaa ggaagtaaaa aatggaatgg cttaaacaat atcgatatcc aattatcgct
     1021 ggtctcatag gcgtatttct ggcttgtttg attgtctcct ttggcttctt caaaacaata
     1081 tttgtattga ttttaggagc actgggagtt gcagctggat tatatatcga aaaaaactat
     1141 atagataaat aaaaaaataa aaattactaa tttaattaaa ggagtttcat atgtcaaacg
     1201 aaaaaaacac aaacactaac gtagaaaaga aagatgctac tgttgtagct cacgaaatca
     1261 aaggggaact tacttacgaa gataaagtta tccaaaaaat cattggtctt tcactagaaa
     1321 acgtttcagg tcttttggga atcgatggtg gtttcttctc aaatcttaaa gaaaaaatcg
     1381 ttaacagcga tgacgtaaca agtggtgtta acgtagaagt tggtaaaaca caagttgcag
     1441 ttgacttaaa cgttattgtt gagtaccaaa aaaatgttcc agctttatat tcagaaatca
     1501 gagaaatcgt atcttcagaa gttgctaaaa tgactgactt ggaaattgtt gaaatcaacg
     1561 taaacgttgt cgacatcaaa actaaagaac agcatgaagc agactcagta agccttcaag
     1621 atcgcgtatc tgacgttgct gaatcaacag gagaattcac ttcagaacaa ttcgaaaaag
     1681 ctaaatctgg tcttggatct ggtttctcaa ctgttcaaga aaaagttagc gaaggtgtag
     1741 aagctgttaa aggtgcagca aatggtgtag tatctcacga aaacactcgt gtaaactaag
     1801 ataaaataaa tataacagga gaaattatca tgtcagtaga agaaaaatta aatcaagcta
     1861 aaggttctat taaagaaggt gttgggaaag ccatcggtga tgaaaaaatg gaaaaagaag
     1921 gagcagctga aaaagttgtt tctaaagtaa aagaagttgc cgaagacgct aaagacgctg
     1981 tagaaggtgc tgtagaaggt gttaaaaaca tgttgagtgg cgacgataaa taaggttaaa
     2041 agttacttta tctttttggt aacattagtc aaaagagtct gagtcaagat gattctcaga
     2101 aaacaaaaag ctagagattc ccaattgcgg aactctagct ttttaatttt gcctctttct
     2161 cttattatat ttcagcaggt tgttggccat gagtatgaat cccatgtcaa ttctcacttg
     2221 acgcttacct ctcagatgac atctcttata acccaaacaa acctttatct gcccaaagac
     2281 agatttcata tcaatcttac gtttagcgaa aatttgtcta cccttggaag ataaaagtgc
     2341 ctgatattct ttagttttta aacactggta acgttcattc atatacagtc ccttttgagg
     2401 ggctgattca ggttcataat cgcagtcaac attgatttca aggctgtttg ctttctatct
     2461 cccctttttc atgatatatt ttcgtacggt gcttcaatag tttctatagt aaaatgaacc
     2521 caaaatagta cacgttgcgg tataatgttc ttgtggcata ttcattagat tttcgtaaaa
     2581 agttctctcc tatttgtgag cgaacaggta tagtcaattg attgtcagtt tgaagaccaa
     2641 gagtcgtaag gcaaaggata tggcagaatc catccaaggg tggctggcac aatttctagt
     2701 gaacctcttt aaatctatta cgtttgactg tggaaaagag ttttcaaaat ggaaagatat
     2761 ttccaatcat cacgatagtg agagcttttt tgcgaatcta ggatgtccaa gacagcggtg
     2821 tctcaacgaa cattcaaata gacttttaag gtgtcatgac ttgccaaagc agacagattt
     2881 caacgaagtc agtcaagaat tttaggctgg gtaaaaactc aatttcagga gaaaatgaaa
     2941 taaatattcc cacaataaaa tgcatagtat caaagttttt ccaacacctg atattatgca
     3001 ttttttaatt ttaaagactt tttcccagcc tcaagaaatc acatcccacc taaatccttt
     3061 ggataccaaa tacctcatca ggtattttct gagttggtaa gactgtctag cttaatttga
     3121 caaatggagg gcgttaaatc cagtttttac aggaagtcta tttaaatatt ttcacactga
     3181 ccttacaaaa tatgaaataa attatataaa gtcattccca tgacaaagaa taacatccct
     3241 ttaaaacagt atcttaccca attttcaggt aagacttttg atacaaccgt ccccaatacc
     3301 cctccgcata tagaagcaag aaaaataact ggaacaggtg ctaaatgata ctgatttaaa
     3361 cctgtaacca caacaattgt agccaaatga gacagctggg aaaagaaaat aattgcaaga
     3421 gaatacatcg ttgcttcttt tatcgaaata gaaaaaaaca ccatcaataa agatacattg
     3481 agcggaccac caccaatccc taaaaaacta gaaattaagc ccaatagaag accacaaatc
     3541 atatagaatc ctatcttatc aaattgataa gtttttttaa aatctgttaa aacaaatgat
     3601 acaagtagca tcacaaatag taaaatcatt tgaacaatgg atactagccg tactgataat
     3661 tgagataaca aaacttgaaa aataagatga cctagaaatc ctcctaaaac agaagaaaag
     3721 gataccgtaa aaatcaatct ccattttatc tctttacttt gtgaaaatct tttgattgtt
     3781 gaaataatcg ccattataaa aacagagaaa ctagaataaa aagcaatatc actgaccgaa
     3841 tggtacccaa aactatccat aagtggctta attataattc caccacccat gcctgatata
     3901 gaacccaatc cactagctat tataatgatt agaaaataaa taatctcaac cactttttaa
     3961 gtccatccta ttctttcaaa catctaaaac ctagatggct actagtggaa gtagaaatac
     4021 atccatttct agcagctact cggtatcgat tacaataaga acaatgacat aaaaaggaac
     4081 ctcctctgat agcatactcc tcatcttgta tcccatattt tggtaactca tagtcatctt
     4141 cattaaaact agctaataag gtatatctcg gattgcgaca ccattcccaa acattcccaa
     4201 tcatttgata tagaccaaaa tcattaggta aaaattcata gacaggagcc gttcctataa
     4261 atccatctaa ggcagtattt tcataaggaa atcttccttg ccaagtattg gcatgataat
     4321 atccaccttc taaaagagta tctccccaag gatattcaga ttgtcttcct cctctagcag
     4381 catattccca ctgtgcttca gtcggtaaag acattccgct ccaattacag aaagccaatg
     4441 catcttctaa agcaacatga actactggat ggtcttctaa acccactaga ttactgttct
     4501 caccgtaggg atgtttccag caagcgttcg aaacttgtaa ccaccacgga gccccagcag
     4561 gatgaggata tccctccctt tctgcctccg gaacgaacaa tataaaaaca aaagaccact
     4621 cttgtcgctc agctagtgtt ttatagcctg tttctttcac aaattgagca aattcttgat
     4681 tcgtaactgg agtatccgca atggaaaaat cctttacact aacagcgact tgaggacctt
     4741 caaaatcatc taaaaagccc tcttcagaat ttgttcccat cataaatgtc ccacccttga
     4801 tttttttcat tttcatgatt gactatcccc cgttttcgtt agagttggcg ttattttaga
     4861 aagttcaaca ggaactaact cttcatccac aacaaaacct tcttctctat atctaagaaa
     4921 gtctactaat tttttcttca tctgacgaac aataggttga tatttttcac ttggatacaa
     4981 atcattcatt tcatgcggat cttttttcat atcaaataac tgataatgat ttaaaacagg
     5041 aaaccagata aatttccact ggtctgtcaa aatatattga ctagaatctt ttcctaaagc
     5101 atgttcacca tgaaattctg ttcgccaccc ctcgtactgt ccaaataata aattcttaac
     5161 actccgtcca tctagttcat ctgtagtagt tcctcctgcc aaatccacga gtgaaggaaa
     5221 aatatcttga attttcacta attgcttgat tgttccccta ttaccagcta tcaatccagc
     5281 cggatcgtaa ataaacgaag gaatgtggat acttccctga taaggatatc cctttctaaa
     5341 cagataatgt tcaccaagct gatctccatg atccgaaaca aaccagataa tcgtatcttt
     5401 atcatgacga aattctttta gggcagtcaa aaagcgacta atttgatggt ctatatgagt
     5461 aatcaatcca aaataagcag caaccattct tctttgatca tcttccttta atttccctct
     5521 taaagcataa atagacggaa tttgcttttc taatacttcc caattcccga tatgcaaatc
     5581 gagaaattga ggcaagcgtt ccatatacat atcaaaatag tattttgggg gatttaatgg
     5641 agcatgtggt ttttcaaaag acattttgag aaaaaaagga accgttggat ctcttctttg
     5701 taaaaatgaa atggactcac tcacaaccca gtttgttgga tgtaacttct catctttatc
     5761 ccaaggtcta gcttcccaag aattacaatc cattccgtca tcaatcaaat caacatcata
     5821 accaacttta ccctttaaaa aggctagata gtcactagca taatcaaatt gacttccata
     5881 agccttatca tactttctat caacatgtag atacccatcg tgaagtaaga catgatcaaa
     5941 cccaagtctc tgtctggaag gaaaaacatg catcttacca atacactctg tttgataacc
     6001 catatcttta aagacttttg gaagagtatt agtaaaattc caaggcacct catcttgata
     6061 accaacacgt ccacttttat cttggtctaa gccagtcaat aaagctgccc tagcaggaac
     6121 gcaagaagga actggagaat aggcattttc aaaattataa cctacactag ccatcatatc
     6181 taatgttgga gtgctaacta gcttatcctt actattcaag gataagacgt ctgctctcat
     6241 ttgatctaca acaatcaaaa taatatttgg ctgttttgtc tgaaccataa aatctccttt
     6301 ctaatatggc aaaagaggca caagaagata tctaccttta ctgcacccct ttctatatca
     6361 atctctctat ataaaacaat aacattcttg ttatgtttta tagaaaaatg aactaaaata
     6421 tgactaaatc gattaggaaa ttcaaatcat tttctagtac tgttttagaa gttacagtgt
     6481 actattccaa cttcaataaa ctataaacct ttgtctaata acaattttag tggagataag
     6541 aaatcctaca cctaactcat cttacacgta atctatttct attttatcac aaaaaacgca
     6601 agtaagacca ttaactcaat tcagttttat ctgccatttt cacaaatggg aaataagtca
     6661 agacactaat aatcaaacaa acaactgata agatgatggc acgccaatca aatgctgtag
     6721 agaagaaacc atataaaatt ggaggcatta cccaagtaac attttgtgta acaggtgaaa
     6781 caagacccca gcttgttgcc cagtaagcta ccgttgccat gaaaaccggg ctaagtacaa
     6841 atggtataaa tagcaaagga ttcaagacaa ctggtaaacc ataattgacc ggctcaccaa
     6901 tattaaacag aactggtgct agaccaagtt tagcaacttt tcgataatga ctgtttcttg
     6961 aaaaaattaa aatagcaagt actaatccta atcctccaaa ccagacaaac gccccaaaag
     7021 acccacttgt ccatatataa ggaatcggtt cacctttttg gaaagcatcc agattcgcta
     7081 acatagcaac tccaaatagc ccttccatga tgggagccaa tacatttcct ccatggagac
     7141 caaaaaacca gaataactta ttcaaaaaga tcatcagaat aactgcaaag aaactttgag
     7201 acaaacctag taatggcgtt tgtaacacct tgtaaaccca atcaatcaat aagtcattgc
     7261 taagtaaatg gaaaacataa gtcaagatgg ctactatata catcgccata aatcctggaa
     7321 tgatagaagt gaacggctta gcaatcgcag ggggaactga atctggtaac ttgattaccc
     7381 agttcttttt cattacttta cagaaaataa tagaggctaa aaatccaatc atcatggctg
     7441 taaagtagcc tctggcattg atatggtttc ctggaatcac attcccaata gttaccatca
     7501 gatttttacc atcaaatgct agattatcaa ttccttgtaa gattttatct aatttcacat
     7561 ctcctacatt tgccaaaggg aaactctttg taactgtact tccaatcgaa atgacaaacg
     7621 aggcaagtga taccaaacca gcagaaactg tatcaacctt gtaaatctta gcaatattca
     7681 ctcccaagca atagatgaac aacaaggaaa caattggtat acttcccttg aataccaaat
     7741 tattgatgtc aacaagccac tgaaaggttt tcgtaatact ttctaggtga aattgttgtg
     7801 gtaaatccac tagaaaagca tttaataaca aagcaatgga acctgtcata ataacaggca
     7861 tagtccccac aaatgaatca cgtaaagcaa ctaaaaactt ctgatttcca actttcattg
     7921 caattggaga aagtttttct tgcattttat ccaacattgt attcatacca aactcctaat
     7981 ttttttcaaa tcgtttgtac acttctacca cttcttttgc taagtcaaca aaggtcagac
     8041 tcgtcattaa atgatcttgc gcgtgtacca tcaagaggct aattgaagtt tcttccccct
     8101 gtgcctctct tgtcaacatt tctgtttgag ccttatgcgc ctgtaataag gcagcattcg
     8161 catcagctaa tctttgattg gcttttgaga aatcaccttt ttttgctgcc tgaatagcct
     8221 ccatagcatt acttttggct tccccaccat acataattag ccccattaca gattctaaat
     8281 tactttcatt catagcattc tcctcaatct tagtctaata aactttcagc taaatctaag
     8341 actttagaac cattcatcat tccgtaatct gtcatcggaa taaccgccac aggaatctgt
     8401 ctatctttta gtttttcttg aaagtcccct agtaaatagc gaacttgagg acctaaaagc
     8461 aacacattta cttcctttgt tgctacaatt tcttctgctt caggagctgg aactgcaaaa
     8521 atttctgcat ccaacccctt atcttctgct gccttttgca tctttgtcac tagcagactt
     8581 gtactcatac ctgctgcaca cgctaacata attgttactt tagccataag cttactcctt
     8641 tatcacctat ttactgacct agccaagcga gatactgtat gtctcactcc tctaattgcc
     8701 ttgctcaagg cataaatatt atcgactgtt gccagtcccc catatcctgc gtcacctata
     8761 tgttgaatat caactccaca aattttattt ctaagtgcaa tttccttgat agtatctgta
     8821 tcagatgttt cttggctagt accaatagca ctcaatacaa gaccaccctt actatgaacg
     8881 agatcaacga cttcacgcaa ctcttggtca tgaaaggctg gaacggttcc aactgctgga
     8941 acaagtatca catccgcacc tgcttccaac aattgctctg cgacagaaag ctctgccaca
     9001 ggctcattca ctcctgcccc gtgcatctta cctgcaataa tcaaaccaga aaagttttcc
     9061 ttagcagttt gaacagcctt aatgatttct cgattgctaa ctcctgttcc aggatttcca
     9121 gtcaaacaga caaagtcaaa acctaactcc tctattcgat tcaatgtttc aacactagca
     9181 acacgacctg caacaatttc ctgtgtttcc tctagcatct ttgcagatgg gtcaatcggt
     9241 tccaaattta caccaattgg acaagcaaca agctggtgta agcgatgaat aacatcatca
     9301 cctgaactat ccaaagcata aattttaggc tcaaaaacat caacacaatt caataaaatc
     9361 atatcagctc caaaagctct agcaatttca gaattagtta tatccccaac aaatgtctca
     9421 cgagtaacta cattttcaga tagaacaact ctaccttcac ttgctaaaat actttgtttt
     9481 aattcttcag cattcatctg taatatctca gatggatttg cactaattaa acgtttcatt
     9541 ctcaatcctc caataactta aaccgttttt caatagctat tacaaatggt aaataaagta
     9601 agacatccaa aacaatcaat acaatttgta ataatgaacc agaaatactt cctgtagcaa
     9661 gtaaaccact tataacaggt ggcatagtcc aacctggatc tgtataagtt agcggaacca
     9721 aacctgatgc cattgctccc cacgctacta gtaagttaaa cattggagct aagataaatg
     9781 gaactagtaa caaaatgttc aaaacaatag gaacgccaaa cattgctggt tcatttatat
     9841 taaataatcc aggtataaca gttataggtg ccaaagtttt tagttgttta ctagctttct
     9901 tcttatgtgc taaatatcct aacgcaagaa ctaaacctat ggttgcacca ccgccaccta
     9961 tgaatacaaa attatccata aatacgctag taaaaatatt tggaagagtt tctccagttt
    10021 gataagctac tttatttgca tctagattag ctaaccataa cggtttcata actgcattaa
    10081 caacatttcc tccgtgtaat cctacaaacc aaaaactact attaaggaaa attaagataa
    10141 gaagaccaat aacattattt cctaaaagtc caagtggacc tcccaaagct acttgagcaa
    10201 tttcatgaag attaggtaaa cttaatttat ctaaagttgc ataaacaatc aaccaaccaa
    10261 caatagtcac tgcaccagga ataatggcac taaagctttt agatactgct ggtggaacac
    10321 catccggcat ttttatctgt atattatgat ttataaacca ttggtagata tagccattaa
    10381 tcaatcctaa aatcatagca acaaataaac cttttgatgc catgaaagcg gtaggcattc
    10441 ctgctccagc ctctcctcta atgaaaggcg taactgtaat aaaagatgat aatgacacaa
    10501 taccagcagg aataccatca actttgtatt gtctagccat aaagtaagcg ataccaaaac
    10561 tagctacaag accaagtaat ccaaaactac tatcaacacc cttccataaa tagtcagcaa
    10621 caccaatatc acccagatat ttttcccatc ctggaatagg aaaacttgca ataaccatta
    10681 gtaatgaacc tatcaacaat aaaggtatag ttagagtaat accgtctcga atagaaacca
    10741 acgctttatt attacccaat ctagccgcta ctggaagtaa cttttcttgt aataattttt
    10801 ccataacctt ttcctcttaa atatatttta ttatcaaaag ttatcaatta tctttatttt
    10861 ttgacgtcaa gttgttattt gattatcttt tgttatttat attttacaac tataagaaag
    10921 ccttgtcaag gatttgtgta aacatttgat tattttttat tatcaatata taataaaaag
    10981 agaccagtaa gtaatgaaaa gcttaaaaag attaacatct acatttatcc atagcaaaaa
    11041 atcataggat tttaagaatc tgacaactag gaagaaaact aatatgacct tatctaagaa
    11101 acaattacaa ctaagagcta aaatactgga aacagtttac acattaggtc ccatttcacg
    11161 aattgaaatc gctactaaaa caggaataac acctgcaaca actagcagta tcacaaatga
    11221 tctgattaaa gaaaatattc tcttagaact tggtgaagac gaacacgata caagcgtagg
    11281 gagaaaaaaa atcctgctag acattcaagc taaacgattt tactacattg gttgtgaact
    11341 atctgaaaaa catttcactt ttgctttagg agataatcta ggaaatatct taaaggaaga
    11401 gaaagaaatt gttactaaac agttaatcca agaaaaggga aatcaactca ttaaccagac
    11461 actaaagcaa ttcttaaata actgctctga ttatgaaata gaagcaattg gaatcgcgct
    11521 acctggtcgc tatttagata attataaaat aacaacaaac aatcctttat ggcaacatat
    11581 cgacttagaa atgattcaat cccactttga taagcctttg tttttctcta acaatgttaa
    11641 ctgtatggct ataggtaaac gcctatttag tcgccaacag aatgacccta attttgctta
    11701 ttttcatttt gctagaggta tgcactgttc ttatatctac gacggaaaca tttatgggaa
    11761 aggaaatcta atgattggag aaatagggca tacagttgtt tcatctgagg gagaagaatg
    11821 tagctgcggg cgcaagggat gcttacaaac ttttgctgga gaatcttggt taatcaaaaa
    11881 atcaaaaatt ctatatcatc aatctcccta ttctctactt cctagtttag tcaaaaatgc
    11941 cgatgatatt gatatccaag ttattttaac cgcttatcaa ttaggtgaca ctggaataat
    12001 cacacttatc catcaagcct tactctatct tagtcaaacc attttaaata tcagtatgat
    12061 gattgactct caaaaaatct acctacatag tcctttacta acaaatcaac acatcatcca
    12121 aaaactatat agtgaaatga actacaaacc caaactgctc tataatcgcc tacctgaagt
    12181 cattattgaa ccttacaatg attttacagc cgcacactca gctattgcac tttgtttgta
    12241 tcatacaatt ctacattctt aattttctat tacatttaat aaataggcta aaaagaggga
    12301 gtatatcata aaaagcgaac aaacctgttt tctgaaaatc agaattctgt tttgttcact
    12361 ttctttatat ttggaattat actcctatct cccctttttc ataatgtata gtaaaatgaa
    12421 ataataacag gacgaatcga tcgggacagt caaatcgatt tctaacaatg ttttagaagt
    12481 agaggtgtac tattctagtt tcaatctact atattttcgt acaggtgctt caaccatttg
    12541 aacgatttca aatccttctt tttggtaaag attctgagct atttgatttg cctcgaagac
    12601 atttagagaa atactatcta tatcttcatt ttcaaaggcc aaactaacaa atttccttaa
    12661 agccttgcta cctaagcctt gctcctgttt ctggggggtg ataaaaaatc tcccgatatg
    12721 aagattgctg tcttctagcc tgattttctg gataaatccc acaaactctt gttcatcaaa
    12781 gattgaaaag actccttcca aggcttgaag ggtcagtaga aaaggaatcc ttggtcccat
    12841 ccattgttct tgaaaggatt tgcctaggga gttggaccac tggcatacaa attgagcgtt
    12901 ttctgtgctc accttttctt caaaacgaat tgtcatcttt tcctcaccac cttatctatg
    12961 tttctccatt atactatttc tcccattttt tacgaataga taagtatgat tgatttttat
    13021 ttttttctcg tcgggagcat tctcgcttcc tttcttggtt tggtcattga ccgttttcca
    13081 gagcaatcca ttatcagttc agccagtcac tgcgattcct gtcagactcc cttgcgtcct
    13141 ttagatttga ttccgattct ctcacaggtc ttcaatcgct ttcgctgtcg ctactgcaaa
    13201 gttcgctatc ctgtctggta tgccctcttt gaattaagct taggactcct ctttctgctt
    13261 tgctcttggg gatggctctc cttggggcaa gtcgtcctaa tcaccgctgg tttgaccttg
    13321 ggtatctacg actttcacca tcagaaatat cccttactgg tctggatgac tttccagcta
    13381 atcctaatag cttcctctgg ctggaatctg gtcatggtct ccttcctcat acttggaatt
    13441 ttggctcatt ttatcgatat ccgcatgggt gcaggggatt tcctcttttt agcttcttgt
    13501 gctctcgtct ttagcgtaac ggagttactg atcttgattc agttcgcttc tgcgacgggt
    13561 atcctggcct ttctcctgca aaagaaaaag gaaagacttc ctttcgtgcc tttcctctta
    13621 cttgctactt gtttgattat ttttggtaag ctactgcttg tctgataaaa tccaatttct
    13681 gccatatgtc cttcatgaaa ttatttcaca gttaaattat aaattatttc ttttgtacaa
    13741 agggatgatg ttatcaaatc gatctgttct tctatcttct tgatactgat caaaaaattt
    13801 catttcgact gaaaatattt cgcttataaa ctgtaaacga atactttgtt tagacattat
    13861 agtcgctaga ctgactagat gattactcaa aacgacgtcc agaatactct ttactttgct
    13921 tggtttttta acaaaaattt gatcatccaa aggttcaatc attttgtaac ctttttgcgc
    13981 aatttgacga taaaagtaag aatgttgctt tggagtcaat aatcctaact taaaagctcg
    14041 atactctaaa gcctgtatcg aaacattcaa atccgacttc aataaaatat aactatcagg
    14101 attgctgaca cgcttgccaa ccctctcttc aaatttgact aaaaactctt cttttggcaa
    14161 taaaaaacat gatgcaaaat aatttgcttc ttgctccaaa cgatcgccat cttcattcat
    14221 atctttatat ttatgtaaaa gaatatgtcc tagctcatga gctaagtcaa aatttcgacg
    14281 tacagatgat ttattcgttc ccaacacaat ataaggtctt cccaattttg accatgcgct
    14341 ataagcatca gcttggccat taattaatcg ttccacgata tagatgcctg aacgttctaa
    14401 tttataaagc aaatcatgat tatcttttga aatacctaat ttttccctgg cataaagagc
    14461 caattcctca atggattctc ccttatgata agattcactc actacattac ttaagtcatg
    14521 aattgtaata ttaggtataa ttacaaaact ttcaaaataa tcaatcaaac tatctacctt
    14581 atgtaaatac atagtttgaa tatctattgt tttccgtgtt gctaggtctg catttctaaa
    14641 ggcaattaca gaagaatcaa atcgaatgct ctcttcttcc tgttcaaaat aagttaaatc
    14701 aacatgaaat tggttggcca aatgcatttt ggttgataat ttaggtttcg tttcgttgga
    14761 ctcaaactgc caaatggctt gttccgttaa attaattctc tgagctaatt ctgctctact
    14821 taaaccattt aacagccgca attctttcaa tacccgacca ttaaacattt acatactcct
    14881 tactactttt gaccttcttg tttttctatt cttggaataa tttcaaaatc ttctgtttcc
    14941 gataattctg aaaaattagg aatatcttga tatttagctt cttcgaaatg gtacgaactt
    15001 gattgaatat actcagacaa atcttgaatc aagtgtaact gaccagttcg tgcatcaggc
    15061 ataacaacat ctacagatat aatattgttt tctgagtccg cctcataagt taaaatcata
    15121 aatttttcga tattcgaatt tttagtagct tgttcaattt cttgaatcat ttcatcagaa
    15181 actaactcca tctgaattgg aaaggaatga ctatcttcat catttttgta ggaagaatgt
    15241 tgattaagat aaagtgtatt catctgagca tattcaaata agtagccact cttatttttt
    15301 tgtaccaaag gaaattggtt cgtaagtcgc ttcttaccct ttataattaa caatactttc
    15361 ccatattttt ctgtatttgt ttcaaattct aaatatcccc aagtctgtcc tgctaattgt
    15421 aatttatact caaacaaatc tgctgatgca aatgcagtat caatatgatt aggtcgcgtc
    15481 catgcataac cattcgacac tatcattgtc tctctttttt ctagacgttc atctacataa
    15541 tctttttgcc ctttcatcaa agtatctaca attctttgtg cctcaagcga atcaaagaga
    15601 tcctgattca acataattct tcctcctcca aatacttttt aatgaattat atcattttct
    15661 taaagaaatt actacaataa ttagcttttt cttaaagttc tgtgtcagag taatttagaa
    15721 aattatatct tctatagtaa aatcaattaa aaactgaaca aatttattgg gaaattcaaa
    15781 tcactttctg aaaatatttt aggaaccgta gtgtaatatt ccagattcaa tttactataa
    15841 aactggcctt tatcctgcaa aagaaaaagg aaagacttcc tttcgtgcct ttcctcttac
    15901 ttgctacttg tttgattatt tttggtaagc tactgcttgt ctgataaagt cctgaatcgg
    15961 ctctccttgg tggagagctt ttactatttt cgaaccgacg ataacaccat ctgacaccgc
    16021 attgaagcgt tccagatcgg cttgactaga tacaccaaaa cctgtcaaga ctgggatgtc
    16081 ggccacttga tgaagttgcg ccaagtgctt gtccaaatct gcacggtaat tgcctgattt
    16141 ccctgtcact ccattgatgg caacggcata gacgaatccc tccgcccctt caatcaactc
    16201 tttctggcgc tcaattcctg tggtcaagct tactaaagga atcaaggcga tatctgtatc
    16261 tgccaaaaat ggttctacaa agttggcatg ttcatgaggc aggtctggga taatcaagcc
    16321 tttcacagct gtatcagcca gatctttgac aaagttctcc acaccgtact gaaagagggg
    16381 gttgaagtag gtcatgatga ccagtggaat ctctgtttca atggttttca aggtttcaac
    16441 taaaacctgg gtagaggtcc cgtgggctaa actgcgcaag ccagcttctt cgataacagg
    16501 tccatctgca acagggtctg aaaagggaat acccacttca attgcagaga cacccaaatc
    16561 ttctagaaag tggattgttt ctcctagtcc atccaaacct ttctcgtggt caccagccat
    16621 gatataggga acaaaaattc cttttccagt tgcttttata gcattcaatt tttctgttag
    16681 tgtcttaggc atgagcttct cccttctttg ctgcatctgc ttccaagcgg tctttgactt
    16741 gaaccacatc cttgtcccca cgacctgata ggcagacaat catagacttt tctggtccaa
    16801 gttctttggc caatttcacc gcaaaggcga tagcatggct agattccaaa gctgggataa
    16861 tcccttccac acgagacaag agttggaatc cttccaaggc ttcttcgtct gtcacaggga
    16921 catagctggc acgtttaata tcgtggtagt gagaatgctc tggaccgata ccaggatagt
    16981 ccaaacctgc tgagatagag aaggcttcaa gaatttgacc atgggcatct tggagcacat
    17041 ccatgaggga accgtgaagg acacctggac gacccttggt caaggtagct gcgtggtgct
    17101 ccgtatccac accaagccct gctgcttcag ctccatacat agctactgac tcatcttcta
    17161 caaagggatg gaagagcccg atagcattcg acccaccacc aacacaggct actagggcat
    17221 ctggcagatc tcgacctgtc aagtcacggt actgttgttt agcttctcga ccaataacac
    17281 tttggaagtc acgaacgatt tctgggaatg gatgaggacc caaggcagaa ccaaggatat
    17341 agtgggtatc atcgatatta gccacccatg aacgaagggc tgcattgacc gcatccttga
    17401 gcacgcgcga accatctgtc acggcctcga ccttggctcc caaaagctcc atacggaaga
    17461 cattgagggc ttggcgtttg acatcttcct cacccatgta gatggtacat tccatgttaa
    17521 agagggctgc agcagttgca gttgccacac cgtgctgacc agcacccgtt tctgcgataa
    17581 ttttcttttt acccatgcgt ttggcaagcc aaacttgtcc taaggcattg ttaatcttgt
    17641 gggctcctgt atggttaagg tcttcccgtt tgagataaat cttggctccg ccaatatgct
    17701 gggtcaagtt ttttgcgtag taaaggggag tttcacgtcc cacatactgg cgcaaaagtt
    17761 ggtttaattc ctcttggaaa cttgggtctg cctgactttc acggtaggcc ttctccaact
    17821 ccaaaactgc tgtcatcaat gtttctggga caaaacgtcc gccaaatttt ccgtaaaatc
    17881 catctttatt tggttcttga tatgccattc tttaccctct ctataaatct tctaatcttt
    17941 tcatgatctt tttgtccatc tgtctccact ccgcttgata catctactgc atagggagta
    18001 aaatgttgaa ttgcttttac tacattgtct tcattaaggc cacctgcgat aaagaaagac
    18061 tgaggtaatc cagtcgtatc cagttgaccc caatcaaagg gctggccact tcctgccaca
    18121 ggggcatcaa agagtagata atctgcctga gaattgggga catgcccatt tccatctacc
    18181 tgcacagcct gaatactagc acaaggcaaa ttctcaaata aatcatctgc tacctgaccg
    18241 tgaacttgaa ccaagtccaa gccaactttg tcaatcgctt ccagcagttc tacccgactt
    18301 ggtgaaacaa atactccaac ctttttcaca tctgcaggaa taagctttgc caactcagct
    18361 gcctcttcta aagtcacctg tcttttacta ggtgcaaaga caaaaccgat atagtcggct
    18421 cctgctgaaa cggctgtttc caccgcttct ttggtcgata gtccacaaat tttaaccttt
    18481 gtcaatctgc aactccttga ttctctgggc cacattttct gcctgcataa gagctgtccc
    18541 taccaaaatt ccgttaaagt atggggctag tcgttccgca tcctgccctg tgaaaatggc
    18601 agattcagaa atgtaatagc gaccttcctc aaagtaaggg gctaaatcta cactggtctg
    18661 caagtcgacc tcaaaggtag tcaagttgcg gttgttgacc ccgataatct cagcaccaag
    18721 tctgtgggct acctctagtt cagctagatt gtgagtctcc actaagactt ccagaccaag
    18781 ctctgtcgcg tagtcataca gttccttgag gcgttcttcg gacaaggctg ccacaataag
    18841 caagataact gtcgcacctg cattgcgagc gcggatgatt tgcttttcat ctatgataaa
    18901 gtctttgttg agcgtcggaa tctctacctg actggaaatt tcccgtagat aatccaaatg
    18961 ccctttaaag aaaacctcat ctgtcaacac cgaaatcatc actgctccgt tttcttcata
    19021 agtctgggcc tgttgcacaa tatccacatc gagattgata tctcccaaac tagggctagc
    19081 tttcttgacc tcagcgatta cctgcaagcg gtcctgatga ttcttcaaaa attctgccaa
    19141 gcgataggtc tggcgcagag gctggatttg ctccagcttc atctgctcca cctcacgcgc
    19201 cttctgctct aagattcgtg ctaaaaattc ctgactcatt tttggtactc ctgtaacagt
    19261 ctgagttttt caagagcctt gcctctagca atcacttgac gggccaaggc aactccttcc
    19321 ttgatgctat caatcttacc attagcatag aaaccaagac cagcattcaa gactgtcgtt
    19381 tccaagaatg gacttgcttc gtttttcaga acgctaagca aaatttctgc attttcctga
    19441 gcattcccac cacgaatatc ttccatagca tagccttcca ttcccaaatc ctctggagta
    19501 aagcttgaca agctgatttc gccattttca agaagtgcaa tcttggttgt tccgttcaag
    19561 ccagcttcat ccaacccttc tggtccagca accacgatgg cacgtttgcg acccatattt
    19621 ttcaaaacct gagctgtact ttctaggagt tctggacgac taattccaag aagctgtgtt
    19681 tctaaagcca ttggatgaat cagtggacca gtcaagttca taatcgttgg aattcccaat
    19741 tccaaacgag ctggcatgat gtatttcata gctgggtgca tatttttagc gaagagaaag
    19801 acgattccag ttttatcaaa gaccttacct agttcagctg gtttgaggtc aagattgatt
    19861 cccaaggctt cgaggacatc tgcggaacca gatttagaag aaatcgagcg gttaccatgc
    19921 ttggccatgt gaataccgcc accagccaag acaaaggctg cagttgtgga aatattaaaa
    19981 ctgaaagact tgtccccacc tgtaccacag ttgtccatgg catcatgaat ctcagttgga
    20041 atatgctggg catgtcctct catgacttgg gcaatggctg tgcgttcttc aggtgtttcc
    20101 cccttcatct taagagctaa gaggagagaa gcaatctgcg cttcagttac acgcccagtt
    20161 acgatacgct caatgacatc cgtcatttcc acacctgata aattttcaaa ttttgctagt
    20221 ttttcaataa tctctttcat cctagtttcc tcactttaca accttctcga taaaattccg
    20281 aatagaagac aagccgtctg gcgttccaat gctctctgga tggtactgga agccataaat
    20341 cggtaggttt ttatgttgaa tccccatgat ggcttggtca tcagtcgaac gagctgtcac
    20401 ttcaaagtct tctggcattt cctcaatcaa aatactgtga taacgcatga ccgcacgtcc
    20461 atcctcaata ccttgataca aaacagatgg cgcttcaaag ttgatattgc tctgtttccc
    20521 atgcatgact tttggagcca aacctagctt accaccaaag acttctgcaa tggcttggtg
    20581 acccaaacaa atccctagaa tcggcttctt gcctgcaaaa tcacgaatca tgtcttccat
    20641 ctttccagca tcaactggcc aaccaggacc aggagaaaag accagaccat ctgctttttc
    20701 agcttcttca tacagcttgg aatcatcatt tctcagaacc tgaacttctg caaaattccc
    20761 aatgtattgg gccaagttat aggtaaaaga atcatagttg tcaatcaata aaatcatggt
    20821 cttagttctc caattctagt catagatttt gctttgttaa tggtttcttg gtattcgttt
    20881 tgggcgatag agtcgtagac aatccctgcc ccagcctgca cataggctct ttgatttttg
    20941 agaatcatgg ttcggatggc aatggccaaa tccatatcac ccgtcgcaga caagtagccg
    21001 attgctcctg catatacgcc ccgtttttcc gtttccagtt catagatgcg tctcatcgct
    21061 cgaatttttg gtgctccaga aacggttcca gcaggaagcg ttgctttcaa ggcatccatg
    21121 gcagtgagtt ctgcaagcaa acgtcccttg accacactgg tcaaatgcat gacgtagcgg
    21181 aagagctcca cctccatata cttagtaact tggacactgg ccgtttcaga gatgcggcca
    21241 atatcgttac gccccaagtc taccaacatt cgatgttctg ctgtttcctt ctcatcagag
    21301 aggaggtcag tcgccaaggt cttgtcttct tcatccgtag cccctcttgg tcgcgtccct
    21361 gcaatcggat tggttgtcac gatgccattt ttgacagaaa ccaaactttc tggactagct
    21421 ccgatgattt gataatcccc aaaatcatag aaataaaggt aattagaagg attagtcacg
    21481 cggagatttc tgtagaagtc aaatggattt ccagtaactt ctgctgagaa acgctggctg
    21541 agtacacatt ggaacatatc tccgttacga atcaagtcac gagctgtttc taccattccc
    21601 tcaaacttat gtggagcgat atgcggtttg aagtctaacg gagatagatc caaatcttca
    21661 aattcatttg gagcaggaat gcgtaattcc tcaagcactt ggttcaagga tttttccaag
    21721 gcctcttgac tgcgctcact atagagagca tcctctatga catgtatctt ctccttcttg
    21781 tggtcaaaga ccatatagct ctcatagaca aagaaatgca tgtctggcgt cccaattgta
    21841 tcctcaggga tttgaccaat ttcttcataa agcgaaatca tatcgtaacc cacaaaacca
    21901 atggctccac caccaaaagg tagctctgag tggtgctgac tcttatgaat cacttcataa
    21961 aggaaatcca agggatctcg atcaatcact tgaccatttt gataaagaac tccattttca
    22021 aacttaatct caaaaactgg attataggct aggatagaaa aacgagctgt ttccttgtct
    22081 ctcggaatac tctctaagat aaccttatgt tgccccttta agcgcatata agccaagatt
    22141 ggtgataaga catctccatg aatgattcgt tccattgtaa tttccctttc agttctactt
    22201 ctagtcagtg gtgactgtat gaaaaatccc cacgcaaaat aacttgcgtg aggacgaaat
    22261 tcgcggtgcc acctcaatta taggatttct cctatctctc attcctgtct cagatatctc
    22321 ctgtaacagg ctgtgcgata aagggcactc ccttgagaat gatgttttct tctctcgttt
    22381 cagatgaacc caactttaca gctttctctg cttgttttca gcaaccacaa gctctctgtg
    22441 agagaaaaga ctgtaatttt tccatctatt attttttagc ttctagtaat ctgcaatcgc
    22501 agctaggtcc ttgcctccac gaccagagac attgatgaag agatgttcat ctcggtacac
    22561 ctttatactc ttcgaaaatc tcttcaaacc gcgtcaacgt cgccttatcg taggtatggt
    22621 tactgacttc gtcagttcta tctgcaacct caaaacagtg ttttgagcag cctgcggcta
    22681 gtttcctagt ttgctctttg attttcattg agtattacta gcttttttcg tattagtcca
    22741 gcctttttgt ttacttttag taggaggcaa ggagctgtag atagaactca agttcatcaa
    22801 agcgagttaa ggccctaata aaagataaag caaacgacgg atagaaaaaa gcccacacac
    22861 agaatatact tccgtgtgag ggcgttggta acgcggtgcc acctcaatta taaagggact
    22921 atccctttac atctctgcct tgtttaacaa caagctgcac tgtaaggtgt gcgcaccgaa
    22981 ttttcattgt ttcaaattca ttttcaaaat cagcccactt tcactacttc caaccaccta
    23041 ttcacaatca ccacaggctc cctgaagatc aaaaatagtt acttttctga tttgttgaac
    23101 ttattttaat actttgtttt ttctttgtca agactttttt acgatttttt tgaaaatatc
    23161 attcgaatat gaccatgtct tccttagatc gaacatgaac atgtcccact tgttagaaat
    23221 tggatccaac tcaatagaaa ctgaatggag gctaaacaga acttatttta gaacactcca
    23281 tattttccac taggattttc aagaattaaa caatactaga aactctgtct cctaacaaat
    23341 ttaggagaaa cttcaacaga tgtgacactt tcccctttaa taattgctaa aacaccttct
    23401 atcatttctt tagccaattt aacataattg ggagcaattg tagacaaagc tggagtataa
    23461 tactgagaaa taggaatatt atcaaatcca atgatagaaa tatcatctgg aataagaatt
    23521 cctttctcat agcacgcacg aatcaagccc tgaacctttt catctcctga aacaaaaata
    23581 atgtccggat aattttgggt agtcaagtgc tgcattgcat aagaataaac tgaatcaatt
    23641 gtagataagc cataaatgac ttttaaatcc ataaagtaat ttttatcatt cagaaaagaa
    23701 cgcacacctc tttcacgatc cttattaaca tgggattctc cccccataag caaccacata
    23761 tttttaaatt tttcttcagt tacagctttc atcatatcat aagtagcttg aaaattatta
    23821 ttagatacat agactactcc agacgtttga gattcaccga aaacaagaaa aggcatatgg
    23881 ttcttcttta aatactgaat tctgatatca tctacacttt cataaaaaac aataacacca
    23941 tctactaggc tacctgtgct tgatataatt gaattactaa ttgtatcctc ctctccaaag
    24001 tactcaacta tagcattaac accaaattct ttacacgtcc gtaacacttt atctaacagc
    24061 gtatgaaacc aaattaaagg aaaagagtcg atttttttta cagaaatcaa tatatttata
    24121 gcttcttttt tagttaaatt ttttgcatac gcatttggaa tatacgacaa ttcctctata
    24181 actttttgaa tcgcttgata agtttcttct ttaacattta ctccaccatt aataactcgt
    24241 gaaactgttt ttggagaaaa acctgataaa cgtgcaatat cataaatagt tacctttttc
    24301 ccatttatat ttttcatttc agtcctccat tacgaacatt ctaatattac tatacaatat
    24361 ttaatttttt ttaacaagag aatttagtaa attatttaag atccacaaat tcacaaaatt
    24421 aattttacaa atattcttcc ccttcaaaaa agtttaaatt gcatttcaca cctttatttt
    24481 taagaatgtt tccaacttca cgacaaataa attcatatga gaaaaagcta ccataaaatt
    24541 gtagattaac tttttcagta aaatgtgtag gatttataaa aacatataat agcctgtcaa
    24601 tgtaacattt taacatagag ttaatttttt ctttaaagat aacatttgtt atcaactcat
    24661 caggaggtaa atgaaaggca aacaccattt cacaaatatc ataaaaagaa ataaatttgt
    24721 atacttgtat caaacaatta ttatcaaaat attctatttt acctaaatca aaattgattt
    24781 tataatcttt cataaaaacc tctgagcaaa aatctactca aaaattagat gattaaaaca
    24841 tctaaaaaac aaaaggacaa aaacatctgt ccctttgttt actaaatttc agctaatttc
    24901 ttcgacataa ataacaccta caatattagc aatttcttcc atcagtcgaa gatgttcaaa
    24961 tctacctgat aattccagag taataaatga cgctattttt ttgtccggaa catcaaagta
    25021 ttcaattctg tcagaattaa catctccaaa cgctgttctt gaatcggtca ttctgatacc
    25081 attttctgca caataaacca atacacgatt ataggcttct gtagatttaa ccactatata
    25141 caattcaatc attttagaac gattttgcag atattttttt agtggttgga acatggatat
    25201 cacaccccaa acagaaatgg ctactaaaag agctccctca taaaaaccta ctccaatagc
    25261 taatccaatt cctgccgaag cccaaatgcc tgctgcagtt gtcagacctg taattttctt
    25321 tttatctgta ataagaatcg ttccagcgcc tagaaaaccc acacctgata taacttgagc
    25381 tcctaatcgt gtaggatctc ctgtcccaaa tttataagat acgtattcat tcgtcatcat
    25441 aatcaaacat gcagctagac aaacaatact ataagttcgg atgcctgcag gctgggattt
    25501 gctccctctc tctaaaccaa ttatactacc aatgactact gataaaacaa tcctgacaac
    25561 tatttcaata tttgataacc caagactagt ggctgtcatg attatttcct tactttacgc
    25621 cccggtcttt gtgtgaagta taataccgtt ccagaaataa tcatcagaac aattgtataa
    25681 acaaatacca gagcttgtgc attagatgtt gctgtttcat cacctgcaga tcgaatcgta
    25741 atacctaatg gttgagctag gggatggtaa aggaatacag ataagtcgaa gtcagttaat
    25801 aaagagttaa agtttaaagc aataacagag agaacaaccg gtaaaataaa tggaatgata
    25861 accttcatca tagtataaaa aggtgaagca cccatacttc ttgctgcatc ttccatctca
    25921 tcatcaacac taaataaaat agcacgtacc attctataag aaaatgggat ttttacaact
    25981 atatatgcaa taagtagaat taccaaacta cctaccaaaa tctgattcaa gacaagaaat
    26041 tgtggctgat taaaagtaaa taataaactt actgctaaaa gtgtacttgg tagtaaccaa
    26101 ggaagtagag caccatattc aaataagaaa tcaaaacgag atttatgttt tctgacaaca
    26161 cgagcaaata caactgcgag aattgttgct gttgtcgcag caataataga ataaataaag
    26221 ctgaccaaga atggagagaa tgccgcacta ttactaaaga ataagcgata attttctaaa
    26281 gtaaagtttg ataatgttaa gttacctgtt tgaattgcaa ctggatctgt aaatgagtat
    26341 aatactataa aaattagtgg aagcatgaaa actgtgaaca atccatatgc tacaatgtga
    26401 gcaatgatat tccaaggctt agacgcaatt ttttgttttt taagaggcgc tttagtctta
    26461 gagatagaaa tataatttcc acctttttct atcttattca tgatagtaag caaaattgta
    26521 gttgcaatac ctaaaataat tgcaagtaag gcagctaaat cacgagaatt ccccatccct
    26581 gcaaatgtaa taatcattgg atttatagtt tgaaattctt taccaccaac aatcatgggt
    26641 gctgctactg cagataaacc actaagaaaa accataatag taagtgcaaa tagagttgga
    26701 attaaggttg gtaacactac ttttcggaaa acagtaaatg gttttgctcc catatttcga
    26761 gcagcctcaa tagtgtgata gtcaacgctt cgaattgtat ttgttaaaaa caatgtatga
    26821 ttagcagttc ctgaaaatgt cataatgaat aagactgcac catacccaat aaaccagtta
    26881 gggtctaaag aagggataac attttgtaaa aattttgtaa tcaatccata aggaccatag
    26941 acaaatttat atccagtcgc taaaaccact cctccataaa ttaaagaggt catataacct
    27001 aattttaaaa ttttagcacc tttaatatca aagtactctg taaatagaac acaaagaata
    27061 cctacgacat taactgtaat aatgagtgaa aatgctaact taaaactgtt cataatactc
    27121 tgaagtgccc tctgagattt tagaacacga tgtacagcat caagggaaaa ttctcctcct
    27181 tttacaaata cattcactac tagatcaaag tttggataaa taataaatgt tactaagaac
    27241 cagattaacc ctaaacgaat aagccaatct tttaaattta atttatgacg catactgcac
    27301 ctccttaaaa ttgcagaacg tctgatggtg tgataaataa ttccacactt tctccgacag
    27361 atctaatagc agcctgacta tcaatacttg ttacattaag aatctgactt tcagaaactt
    27421 ttattgtata gtgaattgta actccagaaa actcaacatc aataattgtc ccttttagaa
    27481 taaaatcttg ttcagtttca cgattgaatc gaactttctc taatcgaatg tatccttttt
    27541 tatcctctaa gaaaacgctt gtatttttca ataatacttc gtggactgtt tcatcggtca
    27601 aaacattaat atctccaata aaatcacata caaattcagt ttgagaatta tgataaatct
    27661 ctactggtgt accgacctgt tcgatgtatc cattgttaaa gactgcaatt ctatcagata
    27721 aagtcaaggc ttcctcttga tcatgagtaa catataaagt agtaatacct aactcttttt
    27781 gaagtctttt caactctttt ctcaaatcta cacgtaattt tgcgtcaagg tttgacaatg
    27841 gttcatctag acaaagaatt ttaggttcaa gaaccagagt acgagccaat gctacccttt
    27901 gttgttgacc cccagataat tctgatacat tacgctgtaa ctgttgatca gagatcttaa
    27961 tttttgctgc cactgctgat actttagctt taataacatc tggagctacc ttcttaactt
    28021 ttaaaccaaa tgcaatatta tcaaaaacag tcatagttgg aaatagcgca taagattgaa
    28081 atacaatacc aattccacgc ttttcaggtt ccaaatgagt gacatctgtt ccattaactt
    28141 caatacttcc tgatgatgga tctaaaaaac ctaccaatgc tctcaaagta gttgatttac
    28201 cacatcctga aggcccaaga aatgtaaaga gttccccttc atgtatatct aaattcagat
    28261 tatcaattgc aacaaaatca ccatatttaa tttgaatatt atcaaattta atcatctcac
    28321 taactccctc tattactaaa accaaaagcc tctctttatt tcttccttaa atttagaaat
    28381 aatagagaga cttggacata aaaaataact cttatttctt attttacgta ttctaattca
    28441 gctttttcta cccattcatc caaatgcttt ccaacagctt cccagtcaat attttgtggt
    28501 ttcacttgat caacaaattt tttcgtatct tcaggtaact cttttagggc atctttattg
    28561 gcagggatag agccaaagtt tttactgtac tctacttgaa tttctgattg accaaaccaa
    28621 tcaataaatt ctttagctaa cgcttgtttt ttactagtgc ttaaaaccat agtttgttca
    28681 gttacaaatg gtacaccaat ctcaggagtc ataactttga attcaacatt ttgttctttt
    28741 tgtccaatta acgctccaga accccagatc ataccgtatt gaattgggct ttctttatct
    28801 aacgctttaa caactgagct ttcacctttt tgaagagtat aggcatttgc aaagtattct
    28861 tttgcaactt cccatccttt ttctgatacg cctaaatctc ctttttcatc aaggtaacga
    28921 actaagatac ttgctagaat tgcccgtcct gtaccacctt gaagaccata aattgaatat
    28981 ttacctttat acttactacc taattcagtc caatctttag gcatttcttt tacatcaggc
    29041 gccccaatta aaactaatgg ttgaacaatc acaggattat aataattatc tttatctgat
    29101 aaagattgat caattttatc taaccattta ggcttgtact gtactagtaa tttttgatct
    29161 ctaattttat ttgagtcaac agcaccaatt ccaaatacca tatctgcaac tgcattattc
    29221 ttctcagcaa taacacggtc tgctaattga gcgccagcga tatcaaccat ttttatatta
    29281 aaaccagctt cttttgcttt agcagttaac caatcaccac gaccatttga gactgagttc
    29341 gaatagataa ctaattcttg acttttatca gctttttctt cagatgaaga agcagtcgta
    29401 gaatttgaac ctccagagca agcagcaagt gtagtaagag caactcccgt tgcaagtaca
    29461 gtagaccaaa ctttcatttt tttcatgata agttctcctt ttttattatt ttatttaaat
    29521 ttttcgtgat atggaacaaa ttgtctcata tcttcaaata cagtatagtc aatacggttt
    29581 acagtaatag ttggaatctt ctctaataaa atttcagtta attctgctct gactttagta
    29641 aactcttctt cctcctcttc ggttagagga atccgaagat acccaattga aatatggaat
    29701 tgatatctat catgattagg gaaacaaaca cctgcttttt ctgagacata agtacgaatt
    29761 tcttctaatc tctttgcaga agcttcatct gcaggttcaa ctagtatgtt ttgttttccc
    29821 atttcagtta tacgcatatg aatttcttca tccaacaatg gaaaaatttc aagttgttta
    29881 gcaaagtaat catgtatttc ctgtaaaggt gtatctagag gaagattact gctccaaaac
    29941 tccgtttcac gattttcatg gcacaacaat tcaattacag tcatgtgaat agaattcctt
    30001 ggagttaaag taaacttatc gataaatggt aattctctat aacgtgattg aataatatca
    30061 acaacttcca tcaaatcttg tttagtataa agatttgcta caactgtatt cccagggaaa
    30121 tgattaaatt ccccattctc tttgaactta atttttgtta agtttttcat ataaagacct
    30181 tcttttttat atttgacatc ggtgtcatca tgtttacatt atacaatgaa accgtttcct
    30241 ttgtcaagca cttgcaaaca tttttttaaa tttatctttc attaaatatg catttcatta
    30301 aaaggttaag taattttttc aaaatacagc actcatatag acagtatcat caattatagc
    30361 cattgggatt ttttgattgc caattccatg tatctctaca catgtcttca atcgattttg
    30421 ttgtcctcca atttaattcc ttatatgctt tgtctgcatt tgcataacaa gttgcaacgt
    30481 ctcctgaacg tcttggaact attttataag gaatagggat cttattaaca ctttcaaatg
    30541 tatttacaag ttgtaataca ctagtgcctt ctcccgagcc taggttatag atataaacat
    30601 ctgttttttc agatactttt tctaaagctt ttatatgtcc tattgctaaa tctactacat
    30661 ggatataatc acgcacacca gtaccatcaa gcgtatcata atcatttccg aacacactta
    30721 gctctgatag cttacctacc gctacttgtg caatataagg catcaagttg ttaggaattc
    30781 ctgagggatc ttccccaatc aaaccagact catgagcacc aattggattg aaataacgaa
    30841 gcaacgcaat actccattct gaatctgcca catgaacatc ttttaaaatt tgctcaagca
    30901 tcactttcgt atacccataa ggatttgtcg cacttgtttg catcgtctca attagaggtg
    30961 actgattgtt aattccatat acagtcgcac ttgaagaaaa gacaatcttt ttaacattaa
    31021 attctgacat cacttcaaca agtgccaatg tactcataat attatttttg tagtacatca
    31081 caggcttttg cacggattct ccgacagctt tataacctgc aaaatgaatt gcagcatcaa
    31141 tcgattcttg ttcaaatacc tttctcaatg cttgtttatc acaaacatct aattcgtaaa
    31201 acacgggacg tattcctgta attgcttcaa tacggtctag caccaatttg ctagagttcg
    31261 aaaggttgtc gacaatgata acttcctttc ctaaatttag taattctact acggtatggc
    31321 taccaatata accagctccg cctgttacca atattgccat ctgggtttcc tcctaattaa
    31381 ttccaaccga cttaacaaat ctcataaacg cttcatgccc agacggtgta ttcttataaa
    31441 ctcctgcatc ttccagaact ctcgcaaaca cttgtcctgc ttcgtgttga actacgctat
    31501 taacctcttc tttattaatg cgaggatatt tttctttcaa ttggtcggcc cattctaaat
    31561 gataatccgc aattgcatta tcctctccta aaagatattt tccaacttct tctaactctg
    31621 gtttcaaacg aggtggtaat atcgcaagtc ccatcacttc gattaacccg atattttcct
    31681 ttttaatatg ttgtacatct tgatgaggat ggaaaacacc atctgggtat tgttcagtag
    31741 tatgattatc tcttagaaca atatctaatt cgtatctccc gtccacttta cgagcaatag
    31801 gagtcaccgt atggtgtggg acatcttcag tcatagcaat gatgtctact tctaaatctg
    31861 aatattctct ccacttattt agaattttag tagctaaatc taacaagcga tttttatttt
    31921 cactttgtaa cctaattact gacattggcc attttacaat accagcatta acatcctcaa
    31981 agtctttaaa acaaaattca ctctcaaatt ttgctttttc cattgggaaa atatgtttcc
    32041 ctccctggta gtggttatga ctaagaatgg agcctcctga gataggaaga tcagaatttg
    32101 aaccagcaaa atatcctggc aaaatatcaa caatctccaa taattgttca aatgttttag
    32161 aggtaatagc cattggtaca tgttgactat tcaaaaatat cgcatgctca ttaaagtatg
    32221 agtagggaga atactggaat ccccatactt cgtcaccaag tttcaaccga ataattctat
    32281 gattcgaacg tgctggataa tttattcgcc cctgatatcc ttcattttcc atacatagta
    32341 aacatttggg ataattagtt gcttttacta atttttcagc agcaattgtt tttggatctt
    32401 tttcgggttt tgacaaattt atcgtaatct ctagctctcc gtatttagtt gatgctcgaa
    32461 actcaatatt cttagcaata gcagaagttt taatataatc actatcttta cttaacttat
    32521 aaaactcttc aactgcttct tgaggtgata tatcatatga actccaaaaa atatcattta
    32581 atcgactagg taaaggaact atgaaattca ttaactctgc tcctaaacat tccttttcct
    32641 cgattaaatc tttaatttta ccgtttttta aggcgatttc cactaagtaa tcttttattt
    32701 gtttcaggtc attttcatcg gaaatgcgat caattccctc ctcacctatt aacgctagta
    32761 ctctattttt cacatatatt ttgtcaattt cattatacat tccgtattca attactctat
    32821 caacaaaatt atcaataatt gttttcatat atttttcttt ctaatttatg ttcccatatt
    32881 ttctatacat tatccattta taaattgctt gcgtagtatg agcaatttta tcaaggtgat
    32941 gaataatatc taaagcacta attacttcag aaacgttccc atcatcttca aatatgtaat
    33001 tcattatttt cttttccata tttatactaa gctcttctat ctcattctgt ttttgtataa
    33061 caaccatatc taaacatcca gattgttcct ctctataaca agatatagcc ctattcatat
    33121 gcagtccgat aacttcatga agtattttta tttttgaaat aattttcttc aaaatttcat
    33181 tattttgaag aatctgtaga ttttttaaaa tttcaacaat tctatcccca atacgttcaa
    33241 tgtcagttga tatttttatt acactaataa ttcttcttaa gtcatatgaa acaggatgtt
    33301 gtaaacaaat taactcatat ccttttttat caatatttag aactgactca tttatgatta
    33361 aatcttcttt aatcaattct actcgttctt catttgataa atattcaaat aacttctcat
    33421 atttatcaag cacagatacc caaatggtct ctaaattatt tgataattct ataatttcat
    33481 tttctaaata taaccttaac atttaggtac ctcttcttaa caaagttcaa tagtaacaat
    33541 taatatttta aacaatatat caaacatcaa tgactagaat acttgcatca tccttctttc
    33601 catagattgg atcaatagca gaagaattaa atctcatctt aattaactct tcaaaagttt
    33661 tattttgatt attttgatag aattcataaa agccatcgct cattaaaaca atttgttcac
    33721 tagtaacatc tatttgatta ataatagcat ggtctaaaaa tctctcatcc aacgaaccta
    33781 tccagtaccc actcggttga ttagataatt ttctgatttt ttgtaaaata atttttttta
    33841 tttaaaacac tatttgtacc aattgaatct tttatctcat ttttcccttt ttcaaataag
    33901 ttatctactc tatgatcagt tatttccatt tcgtttacta acatgacgca gtcacctagc
    33961 atcatatact ccaacttttt ttctgaaagt ttagcaaata ttggtaagcg ataatatagt
    34021 atattgaaac tagaatagta cacctctact tctaaaacat tgttagaaat cgatttgact
    34081 gtcctgattg atttgtccta ttattatttc attttactat actctgttaa tttatatgag
    34141 tttaaaccga tttcatcttt aacctcgagt aaagcagttt caaatatttg tttaagagtt
    34201 tttgattctt tacaattaac cgacaaactt tctgataaaa tatgtacaac ttctgagact
    34261 gaataaccta tctcctcttt agaattatat aaatctgtag ctccaccaat aatccaaaaa
    34321 tactgatttt gtgaacctac aatatcctca ttttctacgg aacttccttg tatcgaacaa
    34381 attttattta tctttaccat aatacttcaa cccttttagt gtcaaaagta aaccaattcc
    34441 tgtcactgtt aagaatagtt ccataatctt gttcgaacca gtctttggta atttttgttt
    34501 tacatctact atttctttag atttattaat atgattttca gtttctctgc catctccaac
    34561 tattttatag tttacttctt ctgtcttatt atcttgttta ttgtcgatct tgtcattcat
    34621 ttgtctatta tctttacttg agttaaactc tccgttcttc tggttactat caattacatt
    34681 atttgaatta gattgttttt cctctttgtt tttttctttt tcgtttttat cacttaaatt
    34741 atttgttaca attttgtaaa gcccattctc cgttacaata ttgaaattac catcgctatc
    34801 acgtataaca ggttctttcc catttgcatt agatttgatg aatgatatat acttaccgga
    34861 taaattataa aattggttat ttaaaacggt tattttaccc tttgaatcct caataacaat
    34921 tccttcttta cccccgaata tactattctc tgagactact aaattatcac taactcgtaa
    34981 taattcaata tttggttgtt ctgtttcctt agaattatta ttaattacat tttttgttac
    35041 agtaatatct gatacttttc ctaaatattc tgcactatct tttgcaactc gtatcgcttt
    35101 tgttttagga tcggcaatat taaatatatt ttcggcgata accacctgtt tatttaaatc
    35161 taataggtct ttagtgtttt tatagctata agcatttact aaagctgctc cgctttctcg
    35221 ataatgtaca ctctctcctt taactttctt atcaaagcga tttcctttga ttaatacatc
    35281 agtgaatcct gtaaaacgta cacctgcata catcatgtta tcaaaatgat tatttaaaat
    35341 tttaatatta gaggggttct gtgtcgacaa tgtttgatag tgtgtgccaa ttgctgttac
    35401 taattcccca gatttatcac ttttgccaaa ataggaattt tgaatagtca cattttcaga
    35461 ttttttccca tcatcattca aggcataagg aaaacctttt ctagttaatg gttcaatctg
    35521 aatgctctcc ttacttatga tttgcccatc cttcatcgtt ttgggtaagg cttgcccaag
    35581 aaaacgagaa ttatcaacta atacattttt cgaacctgca atttgaatag catgcccttg
    35641 ataactatcc ttgaatgtta cattttttat agttacgtta tttgaattcc caatagcaaa
    35701 tgcacctgaa gaatttataa gtggtagatt ttttgcttta gttccttctt cattcaaagc
    35761 accgttcata tcaatcgtac caccagaata actaatatct tctgttgggc cccattctac
    35821 ttgcgcacca tcatccgtaa ataaacctgt cataaaaaca atggaagggt gattcttaat
    35881 atttatacca tttagaattg tagctttctc attcaattct aagtgtgtat gactttttaa
    35941 aaaaacaatt tcttttacta aataagttcc ttcaggaaaa tatacatttc ctccacctag
    36001 cccttgagct gcagcatcta ttgcatcttg aattgcttgt cgatcatcat gaatcccatc
    36061 acctaccgca ccataatctt ttacacttaa agcagtatct tcaaattctt ttttgataat
    36121 tctgtcactt ataacatctt ccttataact cttattttca ttagtagatg ttactgtaga
    36181 ttcaactgtt ctgttgtcta attgtgaatt ggaacgaata gtaccattag agctgatact
    36241 gttaacactt aacgaattat ctaaaccatt agtggttgaa ttagaggcaa tcatttcagc
    36301 agaacgattc tgattaacag ttggtgaatt atctaaatca ttagtaattg cattagaaga
    36361 ctcttttgta gccatcggtg aagaactagt aacaacttca tccgctaaaa taccttggct
    36421 tcccaaaatt gaaattgcca atagtaccga gcaagtcccc acctttaatt tacgaatact
    36481 gaatacctca ttaggaacaa aatatttcat cagaacctcc aattttttta ctatttttta
    36541 acaattgatt attacttttc ttaaaataga tagagtgaca ccgctgtcat tatctttatc
    36601 atatattttc caaattgaat tgtcaaggaa taacacaaga aaatattaaa atttatactc
    36661 ttcggaaatc tcttcaaact aggtcagtgc cgccttgccc taagtctagg ttactgactt
    36721 ggtcagttct atagtagact gaaactataa tagtacacct ctacttctaa aacattgtta
    36781 gaaatcgatt taactgtccc gatcaatttg tcctattctt atttcatttt actatatcta
    36841 caacctcaaa gcagggtttt gagctatcta tggccaactt cctagtttgc tctttagcct
    36901 tccattcaaa agtgatgcta tctttcttag cttgaatata aaatatccca tttactatat
    36961 ttaaatttat tgatatgttg taaattataa atgaaagaac aaataccttg tcatacaagc
    37021 attcgccagg gatatttacc tgaatatcgc tcatatggcg gattgaaact aaaacactac
    37081 aatatatttc ttaaatagac cttctataaa agctagattt aacctcgata aaaatagatg
    37141 cagtgcttct aaaatactgg aatagggcat ataggtaatc gtagacaagt gttttataga
    37201 ttgtctcgca ggagatctaa tgatgtatag caagcatcac taaacatatg ggatattcgt
    37261 attattataa tatcaacatg ctataaattc tatcatgcaa aagaatgact agaacatgaa
    37321 agacaggcac aaaactttga acaatattct gaaaacaaaa aaagacgcga gtttccacaa
    37381 tctcactcat ggaaactcac gtctttcaaa aaatagggtg aattgaaaac tagaacaaga
    37441 cactagattt tctaaatgat gtctagtaag gattctaaat gctacaccaa attgctcaca
    37501 tcttatttca aaccacggga ctcccacaag aaaggaaaat cctataaaaa ttctctctct
    37561 gaggagaaag aggcctcaac tacaggtgta aactattatc aattgaaaac aacagttttt
    37621 acactcaatt agacttttta gggacaggat cactttcgct tgactgtagt ttgtcatttt
    37681 tttgataaag ttagcacttt ttcagaaact gttttgaaag tctcaatgat atagtctact
    37741 tcttcatcgc ttaatttagt atgaagaggg agggtaattt cattctcaaa gaaggcatag
    37801 gccttaggat agttcgtcat atcaaatcca agattcttat aggctgtcaa gagaggaagc
    37861 ggtttgtagt gaacattact tgcaattcct gctttagcca attcttggat gatgaggttg
    37921 cgttcttcta ggcttgctcc ttctacacgg gtgatgtaga ggtggcgtga agattcgaca
    37981 gtttcagtct tgtgtgccaa aggatggatg cgagaacctg caaaaccact atcatagcgg
    38041 tccacaatgt ccttacggcg ttgcaacaaa cttggatagc ggtccaattg taccaaacca
    38101 agtgaagcca tgatatcggt catgttgcac ttataggctg gtgtaacgat atcgtattcc
    38161 catgacccca gttgcatctt ggcaagagca tccttagttt gcccgtgaag ggaaaggatt
    38221 tggaattcct tgtacatctc ttcgtcatca atcactggat tggctttcca agtcgcactt
    38281 ccaccttctg ccgttgtaaa gttcttaacg gcatggaatg agaaggaagt aaaatcagcg
    38341 atagaaccag aaggttgtcc tttataagta gatcccaaag cgtgggcact atcagagaca
    38401 atgacaatac ggttaaaggc cttttgccac ttgcttgaag cggtaaagaa gtcacgtttt
    38461 ttctccacga cttggaacaa acggtcataa tcgcaaacaa tccctgcgag ctctactggg
    38521 ataatcacct tagttttctc agtgatagct tgctcaagca ggtcatagtc catctcaaac
    38581 gtatctgctt ggatatccac catgacaggg gttgctccca cgtgcgtaat gacactacat
    38641 gaagccgtat aggtcatggc tggaacgatg acttcatcac caggtcccac ttccaaaacg
    38701 cgtaaaatca actccagagc ggctgtcgca gagttgagac aaacagtctt aggtgtctgt
    38761 gtgtaaagag acaagcggcg ctccagttct tttgttttag gacctgttgt gatccaacca
    38821 gaacgcaggg tatccgctac ttcagcaatt tctgcttctg tgatatcagg cggtgaaaat
    38881 ggaatattgt aatttggcat tgatttgctc cttttatctg tactcatttt cttatgacta
    38941 ctttatttta gtacctcaaa cacggtttga aacatgattt tgatgtcccc aaagaaacta
    39001 aactctcgga gataggcgag gttatagcgc atcttttcag gaagaacatg ctccacatag
    39061 gcctgatcaa ctgacagacc tttctccgtc atttgactga tgatggtgtc ctcatccttg
    39121 tagttgatgc tggctggaga ggtaattcct gcttgcaaga gcaaggttgc catcatttca
    39181 gggctatact gctctgtata acgtggcact tcaggtcgtg taccgacaaa ggacatctca
    39241 cctttaagga cattgaccaa ctgaggcagt tcgtccaaac ggacacgtcg gatgaaattt
    39301 ccaaccttgg taatacggct atcgttagca gaagtcacca gacttccttt tttatccgca
    39361 tccgtcacca tggtacggaa cttccaaatc ttgaaccgac ggttgtactg ggtcacacgc
    39421 tcttgcttgt aaatcactgg ccccttacta tccaacttga tccaaatgct caagatgaga
    39481 aagatgggag aggttagaac cagtaagacc aaggccaaaa accagtccaa gcaacgcttg
    39541 aaaatcagcg aacccttcct tttagagaca agctggtagt aagactcaac ctcgcttgat
    39601 ttcatttcca caggcaagtc ttcccatttc agcatgctgt tctcctttgt ttttattata
    39661 ctatttgtca acatttttca ttataccaca aaatggaaaa ggcggtaaaa gaaatctgta
    39721 atttgaagga tttccttcta gtactcaatg aaaatcaaag tacagctttg agattgcaga
    39781 taaagctgac atggtttaaa gagattttca aagagtatag gccatggccc ctgcctgcaa
    39841 actatacatc ttgtgatagg ttcctcccag agtcaagagt tcctcatggg ttccactctc
    39901 gataatgcgt cccttatcca agacatagat gcagttggcg tcttgaatag tagaaaggcg
    39961 gtgagcgata gcaatagttg ttcggccctg tctcatcttc gccagagaag cttgaaccaa
    40021 actttctgtt tcagagtcaa tattggctgt cgcttcatcc aaaatcagga ttttaggctg
    40081 gctggcgact gttctagcaa aggcaagaag ctggcgctgc ccagtagaga agctcgaacc
    40141 acgctcggaa acaggggagt cgtacccctg aggaagttct tgaataaagg aatctgcatc
    40201 cacaaaggct gccgcagcct gaacctgctc atcactgatt tcttggtaca tggcgatatt
    40261 ggacttaata gttccatgat agaggaaggg ttcctgtaaa accaaaccga tgttttttct
    40321 cagctcttct tgactgaaat ccctgatatc cacatcatcc aagagaactc tccctgactg
    40381 gaattcataa aagcgcatga ggacattgat aatagacgat ttccctgaac ctgtatgacc
    40441 tacaaaggca atggtttcac ccttattaac agagaaagaa atgtcatcca gaatcggatg
    40501 tttaccgtca tacgagaaac acacatgttc aaaacggata ttgccttctt tgactttggc
    40561 ttgcccattt tcttgaaggg gctcataggt cctctcatcg attaaggcaa agacacggcc
    40621 tgcagaaacc atagacgttt gcagtgttga aaagttttgc gtcacctcaa tcaaagggtc
    40681 aaagaggcgg ttgatgtact ggataaaagc atacatggtc ccggccgtta tcccgataga
    40741 aagaccacga tagccaaaat aggccatcaa gacagcataa cctagaagtt tcaacaaact
    40801 catggcaggt ctcaaaaaga gggcatccaa ggctacagaa cggttggcat agaccaagtg
    40861 ctcttggttg atttcatcaa attctgcctg caggcgcttc tcttgattaa aggcctggat
    40921 tattctgatt ccctcgatgt tttcagccag cttgctattg atatctgaca agagacttct
    40981 ggttttctca atgattttca ctgatttttt ccgatagaga ttgaccaaaa ggaaaatcaa
    41041 ggggagaaag agcaagacta atgctgtcaa acgaaaatcc aataccaaca tggtataaag
    41101 agttgtcaga aagataaaaa ctgctgagat aaagctagat aaaatcccag aaaacatatc
    41161 actaatcgtc tcggtatcgt tggtcaaacg agaaacgata gaacctgctg gcgtcttgtc
    41221 aaagtaagac atgcccagtt tctccatatt ggcaaaggca tcccgacgaa tatccctaac
    41281 aatactgtaa gacacgcgtg caaagagaag attgccgaca tactgaacta cagtttgtag
    41341 gatgtagaga ccatagtaga ccagcaaaac ggtaacggct agttggttaa gattgctgag
    41401 atactggtcg ataaagtggg aagccacaag gggaatgaca cttttaatga ccgtcgtcgc
    41461 taggagaaaa ctgagtgcca aaaaggtaag gagtccataa ggcttgagat aggacatcaa
    41521 gcgcttcaat acagtccatt gttcttgttt attctgcatc ttcttctccc ttcatttcca
    41581 gctgctgaga ctggtaggtt tgggcatacc agccatccaa agctagcaag tcttcgtgcc
    41641 tgcctcgttc gataatttga ccattttgca ggactaaaat caaatctgca tggacaactg
    41701 cactcaggcg atgggcagtg ataatggttg tcttgtcctt tcgcgtctcc ttgaggttgt
    41761 cgataatcgc atactctgtc ttggcatcta cggcggataa ggaatcatcc aaaatcaaga
    41821 tatcagggtc taaaatcata gcccgactca tagccaaccg ttgcttttga ccaccagaaa
    41881 gactgactcc tttttcacca atcagcgtat caaatccttg aggcatgtct acaatatctt
    41941 ggtaaactcg ggctagctta gtagcttcct cgaccgctga aaggggcaag ttaggattgc
    42001 caaagcggat attgtctagg attgaagtcg caaaaagaaa ctggtcctga ggaacatagc
    42061 ccatgagact gcgaaggtct gtcagacgat agtcccgaat atcgtgaccg tttagataaa
    42121 tggcgccctt atccacatcg tattcacgca agaggagctt gattaaggac gttttcccag
    42181 agcctgtctg cccaaccaag cccagtgttt gcccttttgc caaactaaag tgaatatccg
    42241 tcagtgtttc ctcattttca aaagcaaagc tgtcaatggc atactccaaa cgcccatttt
    42301 caataccatc cagaggaaac tccgggtctt gtacaggaga ttcctgagac aaaagatttt
    42361 caatccgctg gtaagaaacc ttccctcgct gagtagtatt aaagaggaag ccgatggcca
    42421 taagaggcca gaccagcata tccaaatagc tgataaaggt gactagattc ccaactgtaa
    42481 tctgcccttc ctgaaccacc aaggagccaa ccaaaagcgt taaaacatag gacgaaccaa
    42541 caaacaagag aaccataggg tcaaagagac tatcatattt catggtttgc aggttctttt
    42601 ggaaggttaa ttcattgact gcctgaaaag acttcaactc gtctgcctga taaccgaaag
    42661 acttggtcac tttgatacct gatacggact cctgtacctt gttattgagt tcagaaaaag
    42721 cagcttggga ttcgccaaag gccttatgag tctttctccc taggcgacta gtcgcatagg
    42781 ccatgaaagg tagggggaga atggcaacaa gagtcatctg ccatgagatg ctaaagagca
    42841 tggtcaacaa agtcaccaga gccgtgatag aggcatccac cgcagacatg acaccgccac
    42901 ctgctaaacg agtcaaggca ttgatatcat tggttgcgtg tgccatcaga tcacccgtcc
    42961 gataggtttg ataaaaggct gacgacattt ttgtgaaatg cttaaacaag cgagaccgca
    43021 tgatctgtcc caagcaataa gaggtcccaa ggatatacat acgccacaca tagcgcaaat
    43081 agtacatacc aaaggctgca agtagcaagt aaaataggct aagaaggagg tcctgctggg
    43141 ttaattgccc cgatgtgatg gcatcaataa cccgccccat aaccatagga ggaatgagat
    43201 tgaggacgga aaccaagacc agggccacaa ttccgactag ataacggcgt ttttctaact
    43261 tgaaaaacca ccaaagtttt tgaataatgg acataaaatc cctttctgat tgcaaatgga
    43321 aacctgaggc caatactcaa tgaaaatcaa agagcaaact aggaaactag ccgcaggctg
    43381 ctcaaagcac tgctttgagg ttgtagatag aactgacgaa gtcagtaacc tacatacggc
    43441 aaggcgacgt tgacgcggtt tgaagagatt ttcgaagagt acaagacccc aggtttttct
    43501 ttttcataag ttacgactgt aacagcaccc ttgtcatatt cagcaataaa gatattggct
    43561 acattgtcat gcccttgttt actgaggtta tcaagcaacc actcttcgct acgaccaatc
    43621 gattccaaga catctacttg aatcacaccg tcagtcacaa ctggatactt aggattttca
    43681 tctcccattt gcacaacgat aagttgccca ttttgctctt gcacagctcc tttgacttgc
    43741 ttcatctgga aaatcccttg gctacgaagt ttgagggcta catccgatgc agacaaacca
    43801 actgaacgac aggcttctgg gtcaatattc ccatttttga taaggagagt tggcttacca
    43861 tcaatcaaac gtttcacaaa gtgaacattg ttgttgagcc atttgagagt caagaccagt
    43921 ttgattaaaa tttcgatata attaagtgtc atttgttcac atccaccagt tcaattgcgt
    43981 ctgtcttata caattcgact ttctctaaca ggtacttgtc tggctcactt ccgtttaggg
    44041 cacgataata gcgatctccc accttgataa gtgcgccatc tgtgtttgtg gaagtattaa
    44101 catagacttc tgacttgtct actcccaaat ctttggaaac aacctcgatg aaatgaagtg
    44161 aagtttgaaa tttattgtta gaaacttgat tgttttgata agtcgtgatg ctgaccaaaa
    44221 gcagagctaa ataaggccag agctgaaatc atgaccaact cacgaaattc ggttcccttt
    44281 ttatcatggt atgccttaaa agcaaaaaaa actgtcacag ctaatagaac aatcccaaag
    44341 ccaaccatga taccattttg ctgaccgatt tggctgagta catagtcata agagtagaat
    44401 ttcatatatt ttcactccct ttcataaaat cattcttaat tataaacgaa agagagtaat
    44461 ttttcaaacc atacgttggg gaaatagatc tttttttggt ataataaaat ctataatctg
    44521 aatgaaaaag gtaactttat gaaacttatc tcatggaata ttgattccct aaacgctgcc
    44581 ctaactagtg actcagctcg tgccaaattg tcccaagaag tcctacaaac cttggtcgct
    44641 gaaaatgctg atatcattgc tatccaagaa accaagcttt ctgccaaagg acctacaaag
    44701 aaacacgtgg aaattttaga agaactcttc ccaggctacg aaaacacatg gcgctcttcc
    44761 caagagcctg cccgtaaagg ctatgctgga accatgttcc tttataagaa agaacttacg
    44821 cctacgatca gttttccaga aatcggtgcc ccttctacca tggacttgga aggccgtatc
    44881 atcactctag aatttgatgc atttttcgta acccaagttt acactccaaa cgctggtgac
    44941 ggtctcaaac gcttggaaga acgccaagtc tgggatgtta aatatgctga gtatttggct
    45001 gaactagaca aagaaaaacc agtccttgcg accggtgact acaacgtagc ccacaatgaa
    45061 atcgaccttg caaatcctgc tagcaaccgc cgttcacctg gatttactga cgaggaacgt
    45121 gctggattta ccaacctttt ggcaactgga tttacagaca ccttccgcca tgttcatggc
    45181 gatgttcctg aacgctacac ttggtgggca caacgcagca aaacttctaa aatcaacaat
    45241 acaggctgga gaatcgacta ctggctcaca agtaaccgta tcgctgacaa ggtcactaaa
    45301 tctgatatga ttgactcagg tgctcgccaa gaccatacac cgattgtctt ggaaattgac
    45361 ttgtaaggat tttctatatg gactacaatg cggtcattcc cgagtttctt gtatcgaata
    45421 tcgaacagtc ccggtccttc tactgtggtt tactgggttt taggattgaa tactaacgtc
    45481 cagaagaaaa ctttctcttt ctcttgaaga gtgtcaacta atgttagagg agggaacaaa
    45541 ggatcaacta gctgaactga cctacccctt tggtcgtgga gtcaatctct cctttggcat
    45601 aaaggatgtt ccaaaactct atcaaaaagt gatggaggca aactatccta tttatcgtct
    45661 cttgaccaaa agaaagtttc gtgtcagtga tccctatatc tatcctcata aatttgcagt
    45721 tttggatcca gatggctatt ttttaagatt tagcgagtag aataataaaa attgggaaaa
    45781 gtctttaaag ttagaaaaag gcatattgtc aggtgtctaa aaacttgata gtatgccttt
    45841 tatgatggaa aaatcttcta atactcttcg aaaatctctt caagccacgt caacgtcgcc
    45901 ttaccgtagg tatatgatac tgactctgtc aattctatcc acaacctcaa aacagtgttt
    45961 tgaggttgtg gatagcttcc tagtttgctc tttgattttc atttagtata aatgttagct
    46021 tacaatggag tttttgttca ccctctcttc tttttgttcg ctttttaaac caaaacacta
    46081 acaaaatagt tgatttctaa agttatttag tgtaaaataa aaacattggc tcaagcctat
    46141 ttaaaattga atatcgtttt acttgtttat gtcgtgaatt ggcacgacgt ttctacaagg
    46201 tgccggaaca cctaacaata agtaagtcag cagtgagata tggccgtttt tgccatgtct
    46261 atttagggga cttacttaga gattaagtag gtcttttttg aatattttta atatttccct
    46321 taattagtgc ggacgggagg tgaaattatc ctgtgaataa tttcaggaat ccagggaatt
    46381 tcatccctaa tttttgagcc cctagctctt tcatttctag gcttaggcta aaatagttcc
    46441 ccgaactatt ttactctcaa aaatcccgtc atagacaata acaagattat tgtctatgat
    46501 accactacaa cgggaaatat ttgataagac tcgcttcgct cgtaatagtt ttatcaaata
    46561 tatagtatta gcaaaaggga tcactataga aatatttaaa caacaagtaa attaactttt
    46621 agactttagg aggtcttatg aaattattag aagagcgcat cctcaaggat gggcatatct
    46681 tgggtgataa catcctcaag gtagattcct ttttaaccca ccaagttgac tttagcttga
    46741 tgcgagagat tggtaaggtt tttgcggaaa aatttgctgc tactggcatt accaaggtcg
    46801 taaccattga agcgtcgggt attgccccag ccgtttttac agctgaagcc ttaaacgttc
    46861 ccatgatttt cgccaaaaaa gctaagaaca tcaccatgaa cgaaggcatc ttaactgctc
    46921 aagtctactc ctttaccaag caggtgacca gcactgtttc tatcgctgga aaattcctct
    46981 caccagagga caaggttttg attatcgacg atttccttgc taatggccaa gctgctaaag
    47041 gcttgattca aatcatcgaa caggccggtg ccacagtcca agctatcggt atcgtgattg
    47101 agaaatcctt ccaagatggc cgtgatttgc ttgaaaaagc aggctaccct gtcctatcac
    47161 ttgctcgttt ggatcgtttt gaaaatggtc aggtcgtatt taaggaggca gatctctagt
    47221 gcaaactcaa gaaaaacact cgcaagcagc cgttctgggc ttgcagcact tactagccat
    47281 gtactcagga tctatcctgg ttcccatcat gattgcgaca gcccttggct attcagctga
    47341 gcagttgacc tacctgattt ctacagatat cttcatgtgt ggggtggcaa ccttcctcca
    47401 actccaactc aacaaatact ttgggattgg actcccagtc gttcttggag ttgcattcca
    47461 gtcggtcgct cccttgatta tgattgggca aagccatggt agtggcgcta tgtttggtgc
    47521 ccttatcgca tctgggattt acgtggttct tgtttcaggc atcttctcaa aagtagccaa
    47581 tctcttccca tctatcgtaa caggatctgt tattaccacg attggtttaa ccttgatccc
    47641 tgtcgctatt ggaaatatgg gaaataacgt tccagagcca actggtcaaa gtctcttgct
    47701 tgcagctatt actgttctga ttatcctctt gatcaacatc tttaccaaag gatttatcaa
    47761 gtctatctct attttgattg gtctggttgt tggaactgcc attgctgcta ctatgggctt
    47821 ggtggacttc tctcctgttg cggtagctcc acttgtccat gtcccaactc cactctactt
    47881 tgggatgcca acctttgaaa tctcatctat tgtcatgatg tgtattatcg caacggtgtc
    47941 tatggttgag tcaactggtg tttatctagc cttgtctgat atcacaaaag atccactcga
    48001 cagcacgcgc cttcgcaacg gttaccgcgc agaaggtttg gccgtacttc tcggaggaat
    48061 ctttaacacc ttcccttaca ccggattttc acaaaacgtt ggtttggtta aattgtcagg
    48121 catcaaaaaa cgcctgccaa tctactacgc agctggtttc ctggttctcc ttggactgct
    48181 tcctaagttt ggtgcccttg cccaaatcat tccaagctcc gtcctcggcg gtgccatgct
    48241 ggtgatgttt ggttttgtat ctattcaagg gatgcaaatc ctcgcccgag ttgactttgc
    48301 taacaatgaa cacaacttcc ttatcgcagc tgtttcaatc gctgcaggtg tcggtctcaa
    48361 caacagtaat ctctttgtca gcatgccgac agccttccaa atgttcttct caaacggaat
    48421 cgtcgtagcc agcctactcg ccattgtcct caatgccgta ttaaatcata aaaagaaata
    48481 aaaaaaagag gtgcgagcct cttttttgtg tgacaaaata aaaacatcta cctattcata
    48541 tatgctagtg tcatagtcct gaaaatcatc tgcatcaaga acaatttcac aactcttata
    48601 cttttctctt acaagtcgtt cggcttcatc tggattttca gcctctatac ttactaaacg
    48661 tgataaagtt tctgtaattt ctactgtata ctttttcagt tttagattgc tttccaataa
    48721 ttcacctatt aacaataatc tatgatagga gctatgtagc cactctggca atttatctcc
    48781 tacttcccac ccatattttt ccttcatcaa agctagttgt ttttcgtcac caaatttcat
    48841 attttcagat aaccatctca cacaatcggg atctgataag gtacagacga ttaaacttag
    48901 gttatcgtaa cggctttcag tttcataatc aggccagatg acttttaaga aatcatacac
    48961 ctcttctgat gcaacaagtt gtttcgtttt cataatttcc gatactttcc tctaccttta
    49021 aattctatta tttctttgtc tcttaatatt tgaagctgtt gcctaatctt ttctttgata
    49081 tgattgttct taacaaagat attttttagg tcactttcaa aacgatacat atcttcaagg
    49141 gtaaattctg aaccctctat cttatctata caatttagaa tttctattgt ccaacctctt
    49201 gatgacagag agctcttcct taaaaataaa ccttgcttaa attcttttgt aactttttct
    49261 ggatctctaa cttgtccatc ttgcacaaga aatatccttc ctttagaagg tacttgtgat
    49321 aaatcaatgt tacaaccaat ccaacctgct cgtctagcag ttggtgcaag tggttttctt
    49381 tgaataatcg atttcggtgt aacaaattgc ttcggaagga caagaaagtt atttacctca
    49441 aaattttttg tgtaagttaa aaaaaagaaa ttaggattat tatctgcctg cacacgcttc
    49501 atcatcgttg cataagcacc atcattgatt gttgatgaaa aatttccttt tttgctcttt
    49561 agttcaaact cctcactaca atgattacag taaaaatctg ctacaggccg attattttca
    49621 aaatgattta agggattgtt cccacaatta gggcaataag actgacgata aacccaatcc
    49681 tccgttaaga tacgtgcctt ttggctatta cttttataag tttctactaa ttctaaatta
    49741 aagtgtaatt ccatttaaaa attcctcact aatatgagaa ctcactcgat ataagcaatt
    49801 aaaatctact ataactagta taccacatat atgtacctat tacatttgta tttcatcact
    49861 ctcttttata tttccttcta acatatctca taaattaaaa atgagtgaga taaatttatc
    49921 ccactcacct ttctttatat acttacccgt ctttcctcag acctttggcc tgtgacaaac
    49981 atggtaaagg ttgccttaca gacatttctg ccctcttgat tggtgatatc cacatccatc
    50041 acacaggttg tacgaccttg atggacacat tctcctttaa tggtcaatac atcgtcgagt
    50101 tttcctgcct taaggtagtt gatagaggat tggagtgtca ccccatcaag tcccagcgag
    50161 ataaccacca aaccactgat ttggtcacat agcgtgaata gatagccacc atgggcattg
    50221 ccatagtagt tgagcgatga gttcactact ttggtcgtca ccacaacgtg accatctctc
    50281 attttttcaa tttcgtaatt ttcaaaggca gatatagcgt caaaatgaaa gtctttcatc
    50341 gtttcctcct gatatttcaa acgacactat gatactactt tttataggac tgtgcaagga
    50401 gaaagctcct agtctagtaa aattccgacc tgttccacaa agcgcataaa ggctgtctgc
    50461 ccttgttctg tctgcttgta gactcctgca tcctcaagta cacgcacaaa gatagcaccc
    50521 acagagtcct tgacgattgc aagggctttt tctttatccg ttaggtctgg atgttgggat
    50581 ttgagttggt ctgcccactc ctgatgataa tcggcaactg taacagcttc tcctacaaga
    50641 tagctagcga cttgctctac ttcttctttc agacgtggtg gcaagattgc caagcccatg
    50701 acctcaatca agccgatatt ttccttcttg atatgttgga catccttgtg gggatgatag
    50761 atgccatcag gatgctctgc tgaagtctga ttgtctcgca agaccaagtc caactcaaac
    50821 tgtccatcac gcttacgcgc tattggtgtg atggtgtgat gcggtgtccc gtctgtctct
    50881 gctgaaatct gcacactaga atctgaatac tgacgccatt cctggaaaat cttatcagct
    50941 aagttaatca aatcctcttt ggaatccgaa gtcaagcgta ggacagacat tggccacttg
    51001 ataattccag ccttgacctg ctcaaaacca gcaaatcgga aggtcttttg caagggagcc
    51061 aattccatag gaaatacgtg acggcctccc tgataatgat catgagttag aatagagccc
    51121 cccacaatcg gcaggtcggc attagatcca gcaaaatatc ctggaaactg ctctacgata
    51181 gccaacagac gttcaaaact ctgacgacta atggccatgg gacgatgctg gccatctaaa
    51241 aagatacaat gctcattaaa gtaagcatag ggcgaatact ggaaacccca ttcctgacca
    51301 accatttcaa aacggataat ccggtggttg ctgcgagctg ggtggttgac ccgaccatgg
    51361 taaccctcat tctctaaaca aagttgacac tgaggataat tactagcttg caccaacttg
    51421 gctaccgcaa tctctttcgg atccttttca ggcttagaga gattgatggt aatttcaagt
    51481 tctccataat cagatggaac acgataagcg atatttttag caatggcctt gagtttgatg
    51541 tagtcatttt tctgactgag ttgataaaaa tcctctatcg cttgctcagg agagtaggca
    51601 taggcttccc agaagtcacg attgacctga ctcggacaag gagtcaccaa gtccatcaat
    51661 tcagtaccaa ggatttcacg cgcagtctga ctatcctcaa tcgtctctaa tcgaacggtt
    51721 tcctcaacta gctggtcctt gaggtcaatc aatttatcca gattggtctc aacttccaaa
    51781 acaccttctc ccactcgtga caaaacacgg ttggtcaggt agattcgatc catttcctca
    51841 aatgaacttt cagaaatgac atgtgttaca aatttatcta ctaaggtcac tatagagcct
    51901 ccttttgact agtcaaggac gcgagtgcca cctgcaactt cagcgatata gaagcttgga
    51961 gcgtatccaa ctacttcctc gtagtgtttg cctacagctt ccttaaaggc ctcaacagta
    52021 tctttttgaa ccaaggcaat ggcacagcca ccaaaaccag cccctgtcat acgagcaccg
    52081 agaactcctt cttgtgccca agctgtgtga acaagagtat ccaattccaa accagttact
    52141 tcataatcac gctccagaga aacgtgtgac gcattcatca aacgaccaaa tgtttccaaa
    52201 tcacctgctt gaagggctgc ttgagcttta agggtacgtt ggttttcaag cacagcatgg
    52261 cgagcacgtt tcaaacgatt ttcatcttta atcagatagc tatattggtc aacggcccac
    52321 tcgttcaatt cacccagggt ctgaatatcc aaggcaactt gcaattcttc cactgctttt
    52381 tcacactcag cacgacgttc attgtattta gagtccgcca attcacggcg tttgttggtg
    52441 ttcatgataa caacgacatt gtccttcaaa tcaagtggca ccaagtcgta ttctaaagta
    52501 ttggtatcta agtaaatagc acgttggtca gcccccatac caatagcaaa ttggtccata
    52561 atgccagaat ttactccgat aaagttattt tctgtttgtt ttccgatttt aaccaaatcg
    52621 agacgctcta gttttaaatc aaagagatgc tctgccacga ctcctgtcaa gagctccaag
    52681 gatgctgaag aagacaaacc agcaccattt gggatattcc cataaacata aaaatcaaaa
    52741 cctttgtcaa tcacgtgccc agcttcttgc aagaaatgaa ggacaccttt tggataattg
    52801 gtccagttgt gctctttttc aaacttgagg tcagcgagag gcacttcgat aatgcccttg
    52861 tcctcaaagt tagctgagta gaaacgcaag acttggtcgt cacgcttacg agctgcaccg
    52921 taagttccca aggaaatagc agcaggaaaa acgtgcccac cgttgtagtc tgtgtgttca
    52981 ccaatcaaat taatgcggcc tggtgaaaag aaggtttggt ctgcttcttg accaaaaaca
    53041 gcaagaaagt ctttgcgaag ggcttcagta gtaagatgtt gtgccatatg aattctcctt
    53101 tgactgtccg ttaagccatc ttaacgtgta atcgttttct ttctattata tccaaggatt
    53161 tttccaaggt caatcctttt tactaaaatt ttagtaaaat atcagtaaaa agaagaaaaa
    53221 catgatatac taacctaatc aaggaggatt tatggctacc ttaaaagaca ttgcacagct
    53281 agcctctgtc tctatcgcga ccgtatcccg cgtcctcaac cgcgaccaga gcctatctgt
    53341 tacagaagaa accagacacc gtattttaac cgttgctgaa gagctgggct acaccaagca
    53401 cctcaagaca ggcgagtccc acaaacccaa gcaaaagatt gccattatcc aatgggtcag
    53461 cgaacaaggg gagctggacg acctctacta ctaccagatt cgcctaggaa tagaaaaaag
    53521 agcccaagag ttggactatg atatcttgcg ctattttaat gaccatcctt ttaccttaag
    53581 cgaggaagtg attgggattc tctgcatcgg aaaatttagc cgagctcaga tttctgcctt
    53641 tgaagaatac caaaagcctc ttgtatttct agacagcgat acactttccc tgggacatac
    53701 ctgtattatc acggattttt acactgctat gaaacaggtt gtcgattatt tcctcagtca
    53761 agggatggac cgcatcggga ttctaacagg gcttgaggaa acaacagacc aagaagaaat
    53821 cattcaggac aagcgtctag aaaacttcaa aaactacagt caagcgaggg gaatctatca
    53881 tgatgaactg gtctttcaag gaagatttac tgcccagtct ggctatgact taatgaagga
    53941 ggccattcag agcttgggag accaacttcc gccagcattt ttcgcagcca gcgatagttt
    54001 agctatcggt gccctccgtg ccctccaaga agctggaatc agcctgccag atcgcgtcag
    54061 cctcatttca ttcaacgaca ccagtctgac caaacaggtc tatcctcccc tctctagtat
    54121 tacagtttat actgaagaaa tggggcgagc aggtatggat attcttaaca aggaagtcct
    54181 ccacggtcgg aaaatcccta gcctgaccat gctgggaacc agactgacat taagagaaag
    54241 taccctaaat caagaatagg ataacataaa aaacgaatag agttctaaaa ctcctattcg
    54301 ttttttattc gattacaatc atagacttaa ttgtcttacg ttcatccata tctttgtagg
    54361 cttggtcgat atcttccagt ttataacttg aagtaaagac gcgacctgga ttgatatcac
    54421 catcaaggac gacttttagt aaaaattgct tatcgtatgt tgtagcagaa gctgccccac
    54481 ctgctacaga gatattttgc ataaatgtcg aaccaagagc acgattatta tagtgtggga
    54541 ctcctacaaa gcccatacgc cctccattat gaagaacacc tagcgcctgt tctatagcag
    54601 cctccgtacc aacacattca agtgctgcgt ctgctcctcc accgaggatt tcacgcacct
    54661 tggtaattcc ttcttgacca cgttctgcaa caacagctgt cgcacctgac tccatagcca
    54721 tcttttgacg gtcttcatga cggctcataa ggataatttg tgatgctcca cgcatcttag
    54781 ccgcgatgac agcacattga ccaacagccc catcacctat aacaacaacc ttgtcccctt
    54841 tttgaacatt tgcaacacgc gctgcatgat agcctgtcgg catgacatct gcaagagtca
    54901 aaagggactt gagcatccct tctgtataat cagaaggttg accagggatt ttaaccagcg
    54961 cccagtttgc atagtggaag cgaatatatt ctgcctgaaa atcacccccc aaattattgc
    55021 caatatgatt gtcgcaagaa ccgtcaaatc cagcaagaca ggcatcacac tcaccacatc
    55081 catgtgtaaa agggacaatc acaaaatcac ctggtttcac cgtcgtaatg gcttccccag
    55141 cttcttcaac aatcccaatc gcttcgtgtc cactattttt atgtccagct ttcgtttctg
    55201 gattacggta cctccataaa tctgaaccac aaacgcacgc acgaaccaca cgaataatca
    55261 catcatccgc ttctattatt tgcggacgtt caatgctagc aagtccaacc tgacctgcct
    55321 ttgtatatac tgctgatttc atttaaaatt ttccttcctt ataaagttta attttgagat
    55381 ttaaacgatt taaagctgtc tgtagctgag acaagcgctc ctctaatttt tgcttttcct
    55441 cttctaaaat accaagcctc tcctctctcg tttcatctcc cttttggtag agcgacatat
    55501 agtcaactaa actatctaca gagacacccg ccgaacgaaa acacttaata aattccagcg
    55561 cttcgatatc ctgatcttga aaatcacgaa tcccagtagc agtacgagta atcggtggca
    55621 caagaccaac ccgttcataa taccgaatcg tatccgctga aattcccaac aaatcactgg
    55681 cagatttaat attcacacgc taacctcctc tcatttcatt cactgaattc acgctattct
    55741 aactcactta tcttattata taactttgag ttgactccaa gtcaagcatt ttgtatctaa
    55801 tcgaaaaatt tttatcatta acaatcatat atctggagtt tatacaatgc tcttctctta
    55861 ccaatttttg aaatatttaa ataataaaga aattactcta ttccaaataa gatagtaccc
    55921 aagtattttt cacttttttc taatgttgat gctcataact ccgttccaag tcacacacct
    55981 ttcgcttatg ggtttggtga gtttctaggt cagcatcaat ttcaatggta atattttgaa
    56041 aaccacaatc ttttaggaaa attcgaatag actctttaca agtttccata tgttccattt
    56101 cttttagaca aacatgtaca atggcatttt tttccaaagc atccatagtc cagagattaa
    56161 gctgattaag gctggccaca ttgtccaatc gctccaggcc actctttact tgcttgatat
    56221 caagaccttc tggcacagca tccaagaaaa tcttgagtgt agaccaaaaa cgtggaaggg
    56281 cttttgaaag aataaagaaa gaaatgacaa gggacaaaag aggatctagg atataccagt
    56341 ccgtaaatcg aagaacaatc gccatcagga taacagctac ccaccctagc gtatcttcca
    56401 gaaaatgcaa actcagaata gactcattct ttgtctttcc cttaccaacc accagactcg
    56461 ctaacagatt gatagtaatc gcaataattc ctaaccagag aatcccctca tcattgactg
    56521 gttgcggatg caaaatcttc gtgacatttt ccaaaatgac tagaacagag cccgttacga
    56581 gaatcacagc tgttaccaag gctcctagca ggctaaaccg cttatagccc aaggtgtact
    56641 gattgtcttc ttcacgattg gagattgttt ctagaaaagc tgatattcca attgcaatcg
    56701 catctcccaa gtcatgcaca gagtcagcaa gaacagcgct agaaccaaat attccacctg
    56761 caataaactc aacaatggca taagtcaaat ttaagaaaaa agccacccaa acagcatatt
    56821 ttgccttcat atttctcatt cctttgttat aatagattta tgaacacctt gttcattatc
    56881 attatccact aaaactcaaa gaaaggatag aagcaaaacg tcagctttat tcagttctga
    56941 acaatttgcc ttaagtgtcc atatgactaa cattgaccgc cgtatcagca aaaccaaaaa
    57001 agccatctat caagctttta tacaactttt gaatgctaag ggctacgagg ccactactgt
    57061 tcaggatatc attgatctcg cagatgtggg acgatccacc ttttactgtc actatgagag
    57121 taaggagctt cttctggacc agctctgccg ctacctcttc catcatcttt ttgaaagaga
    57181 gcaagccatt tcaaccgagg actacctcgc ccacctcttt ctgcattttc ataaaaacca
    57241 agaccatatc accagtctgc tattttccaa aaatgactac ttcctccgtc aactccagag
    57301 agagcttgag caccacgtct attccgtgct agctgataat ttaaaagaag cccaccctaa
    57361 tctgcctact tcttacctcc aacacttggt catgtccaac tttatcgaga cattgacctg
    57421 gtggctcaaa aaaggtcaag atttcacaga ccaggaagtt gtccaatttt atctagacct
    57481 tctcattcct aaaaattgaa tatagagtaa agcttcagtt gtcttatttc taggttactg
    57541 agttttttat cttttcaaca acaaaagagg acccgccgat cctctttttc atactataaa
    57601 tccttgatta tcaactatat ctgttttaat cgaaatctca aaacagcact ttcaaacatc
    57661 ttttcctagt taagtaaatc agtattctgc ttagctgcct tgctccattg ataccaacca
    57721 actagactgt taataagata aattagatat ttcccttgaa tttgcaggct ttctccccac
    57781 cagagataga ttgaaaaaac attggtagcc gcccagaata tccactgttc acggtaaaca
    57841 gctgtcatga ggatttgccc taccccattg gttgcatctg tgattgaatc acgataggga
    57901 cgattggcac caatagactg ataaatgaag ccaaaggcca accaccaaag cacactaatg
    57961 gaaagatact ttgtccagcc cttgccgtcc agtttacgcg cgacaaactc ctgcttttcc
    58021 ttcttaaact gtgcctgata aatccaaact agaagtccaa ttggctgcat gactgtgaag
    58081 taaagtgtcg tcagcacctc accataaaag cctttctgta gggccaaaat aaggtaaata
    58141 acagagttaa tcaagccaaa aagataatta cttgctcgac cttccgatac aaagattaca
    58201 cagataatcc ctgtcaagct acaaatcatc ccaatccagt caacaatacg atgttcgtaa
    58261 accaactcca gccagagagg aaaacttcct aaaaccagca aataaatcca ctgggcaaaa
    58321 ctacgatggg caaagaggtc atcccagata gccttcatag tttctgaaaa tcctaaatca
    58381 gccatagccg caaccatacg acggtaacca cctgacattt cacctagggt tgttttgata
    58441 ttttcaattt tcttttgcaa ataagtatgc atcatttctc cttttgtttt taaagagccg
    58501 tgtctggata gactttcgga cgcaacgctc tattagataa tgaactgcct atacacaaga
    58561 tttctaacct tagtcgacat gagctgaaac ctcttatttg ttaagtagtt cacaaaatat
    58621 tatacaccta ttttatgaat agtcaactgt atttacagta aaattttaga aaatcatgaa
    58681 aattttctct ttctttccat tttaagtgac attcagtcat tctcacatca aaaaagccca
    58741 gacgaaattg tctgagcatt cttttatcta gtcgtttaag gaagttgagt tcagtatgtt
    58801 taaagtctct gtcccatcat ttcttcaaca aaccttgttc ttggagaaac tccttggcta
    58861 cttgctttgc tgacttgcct tcaacaccga cttggtagtt gagctggctc atctggcttt
    58921 ctgtaatctt accagccaat gtattaagaa ctctttccaa ctctgggtgt ttcttgagaa
    58981 gagcttcttt catgagtgga gccccttgat aaggtgggaa gagttgcttg tcatcttcca
    59041 agacctgtaa atcataacgc tccaattccg catcagtcga ataggcatct gtaatttgaa
    59101 tttcacctga ctgaatcgct tgatagcgaa gagcaggttc caaggttgaa acattgagat
    59161 tgagaccata cattgattgc aagcccttat ttccatcttc acggtcgtta aactcgagtg
    59221 taaagcctgc cttcaactga ccttccactt ttttcaaatc cgaaatggtc ttcaagccat
    59281 attcttgcgc aatctttttc ggaacagcta cagcataggt attttgataa gacataggtt
    59341 tgagataggc tagatgatcc tgtttggcaa tgccatcacg cgccacctga taaacctgct
    59401 ctggctcatg actcacttta ggtgatggtt gaagcaaact ttcagtcacc gtaccagtaa
    59461 attcaggata gatatcaatg tctccgcttt tcaacgcttc ataaaggaaa gttgttttcc
    59521 caaagttagg cttaacggtt gctgttagac ttgtattttc ttctattaaa agtttataca
    59581 tattagccaa aatttctggt tctggaccaa ttttccctgc aataatcacg ttttctttct
    59641 ctttttgaac caagagggct ggactataag atagacccag caataccgtc accaaggcaa
    59701 aacctgagaa aatcgtccgt aattttgctt tttccattac ttttagtagg aagttaaagg
    59761 caatagcaag cactgcagaa gaaagtgccc caatcaaaat caaactggca ttattacggt
    59821 caattcccaa caggataaag gaacccagtc cccctgctcc aatcaaggcc gccaaggttg
    59881 ccgtaccgat aatcaaaaca gctgccgtcc gaatcccaga catgataaca ggcatggcga
    59941 gtggaatttc aaatttcttg agacgttccc atctggtcat cccaaaggca atcccagcct
    60001 cttgcaggtt cggatcaatt cccttcagcc cagtgatagt attttgcaaa atagggaaaa
    60061 tcgcataaat cactagagct gtcaaagccg gcaaggtccc aattcccatc aaagggataa
    60121 agagccccaa caaggccaga gacgggatgg tctggaaaat acctgcaatc tgcaagaccc
    60181 agtcggccag cttctcatga tagcgaagaa aaacagccaa gggaatcgca agcaaaatag
    60241 ctagtaacaa ggtcaaaagt gacaactgca aatgttgaga tagagctgtc aaccaatcac
    60301 taaaacgatc ctgaaaagtt gcaattaaat tagtcatgaa cactacctcc aaacaggtct
    60361 gctacaaagt ctgttgcagg cgcttttaaa attgtctcgg gattcgctac ctggcgaatt
    60421 tctccatcct gcaagacagc aatacggtcc gccaacttca aggcttcatc cgtatcatgg
    60481 gttacaaaaa tcgttgtcat cccaaactct ttatgcaatt cttttgtcag aacctgcaac
    60541 tgttttctcg aaatagcatc caaggccgaa aagggttcat ccatgaggaa aatcttgggc
    60601 tgaccaatca tagctcggac aataccgacc cgttgctgtt ctccaccaga taattcacta
    60661 ggtaagcgat gcccatactc ggctactggt aaaccaacct tagccaaaag ctcttctgtt
    60721 ttcttcgtaa tttcttcctt gctccacccc ttcatttcag gaatgagagc aatattttcc
    60781 gcaactgtta gatttggaaa aagagcaata gcctgtaaaa cataaccagt agaaagacga
    60841 agttcacgct catcatagtc tttgatgcgc ttcccatcca tataaatatt tccatcagtt
    60901 ggttccaaaa gacggttaat catcttgagc atggtcgtct tacctgaccc agaaggccct
    60961 actaaaacca taaattcccc atcctcaatc tgtaagttga catctctcaa gacatccttt
    61021 tctgtgtagc gcagtgctac atttttgtat tcaatcattc tttgtcctca atttaaaact
    61081 tccctcgatt ggtcaagtct tctaccttag gcatgacttc cttattatcc caatgctcca
    61141 caattttccc gttctctaaa cggaagatat cgtactgggc ataagcaacg ccatcaatct
    61201 gagtctgacc atagctaacc acatagtttc cttgtcctaa gagttggaaa acaaagtcaa
    61261 aagtgacact atattcagcc acatagtttt tataagcagc acttccttgt ccaatatcat
    61321 gattatgctg aatcaaatcg tctgccacat aatcactcca ctgctctagc tccccatttt
    61381 ggaaaatttc tgtcaagaaa cggcgaacca gctttttatt ttctgctttc ttgtccaaat
    61441 ccttgatttc aaaatctcca aaaatttgat ctagttggtc attttcaggt gttcgatagt
    61501 agtcaatgac atcccaatgc tcaacaatac gaccattctc atccgcacgg aaagtatccg
    61561 tcgtcaccca ttgagcttct ccaccattca gatattgatg aacatgaaca aagaccagat
    61621 tgccatcctc aatggtgcgg acaatcttaa tctgacgctc tggatgacgc tcaaagaaat
    61681 ctgcaaagaa ggctgcaaat ccttctttcc cgtcaggaac acctgtcgaa tgttggatat
    61741 aggtatcccc tacagactgg gcttgagcct cagcaactcg tccgtcttga atggcatgga
    61801 tgtataggtt gtgagcattt ttcacttgtt gtgacatatt ctaaacctca tttcccttct
    61861 ctttcagatt cgccaaaatt ctttcttgaa aaccttcaaa ttggtgaatt tcttcctctg
    61921 aaaatccttt gtaaaagata gtatccaatt tctgactgac acgatgcccc acttctttct
    61981 gggacttgcc taactccgtt aaaactaaat acttcttacg cttgtctttt ccacacggac
    62041 taacaattac aagcttttgt tcctctagct tttttatcat agtcgtcagc gtattattcg
    62101 caagtccagt cgcaagcgcg atatctgtcg cagttgcgca gccagtttca ctattccata
    62161 aaaccgctaa aatcttgccc tgttcacccc tataaagagc ctcaggatct tgactcagta
    62221 acttttgaaa aatccgccca ttcaacaaac gaatatgatg ggctagcaaa tgaccatctt
    62281 tcataacacc tccaatttat ttcgatatcg aaatgaataa aacaattgta acactcatcg
    62341 ttctaactgt caactatttc gatttagaaa taatttttga taattatcca caccaccata
    62401 ctccggctca actaactttt aacgagagtt tctaaactcc ttcgtcctcc agtctacaaa
    62461 agccttccat tcgtactatc ctatatttta tgaggggaca catttttcct atcagaccat
    62521 ttattttaaa gatagaagta aatcataatt gcttccatct gttcttttat agtatattga
    62581 agttagacta gagcactgta tcttctaaaa cattgataga aagcgatttg aatttcccaa
    62641 tcaatttgtt cgtatttata gcatttcgaa actggaatag gacaccatga ctgctaaaag
    62701 atttctataa attcatttaa tttcctcaat caatttgttc atatcttatt tcattccgct
    62761 ataatttcac cttaccctat ctttttcgta gcacccttca aacagcctat cccctaccgt
    62821 ttgacgattc ctcacttcgc tccacttcca ttacagaagt ttcttcacta ctatgggctc
    62881 ggctgacttc tcatgattcc ttgttactac tatttgaacg ctcacgagat agatcttaca
    62941 aaaaatgctt tgatccacaa tggaatcaaa gcattttaaa gagttcctca tacataagcg
    63001 cagaagtcgc agttcctctg tacttggctt cttctctttt gataaagcga gccaagttga
    63061 gcaactcagg tgctggatgt ttgggattta ggagcaattc acgattgacc aggcctgaga
    63121 gacgaactgc ctgcaattgc tcatttgtag taggcagttt tttagcagtc tctaggagag
    63181 cagcaactaa atcttcactc aaatcatgtc gagcatgatt gtaaagatct tttataaggc
    63241 tttctaggtt tggttctgcc atccctacca cctcccttat ggtttaataa tgtttaatca
    63301 aatcaaccgt tgaacgatcc aatttcttca ccaaggcttg taagaaagct tgcgcttcta
    63361 ggaagtcatc cattgcatag agggtttggt gagaatggat ataacgagcg cagacaccga
    63421 tagttgttga tgggacacca ccatttttca gatgagctgc acctgcatct gttccgcctt
    63481 taccacagta gtattggtac ttgataccag cttcttcagc cgttgtcaaa agaaaatcct
    63541 tcatccctgg gagaagcaag tgacctggat catagaaacg aatcaaggtt ccatctccaa
    63601 tcttgccttg accaccgtag acatcacctg ctggtgagca atcaactgcg aggaagactt
    63661 ctgggtcaaa cttggttgta gaggtatgag cgccacgcag accaacttct tcttggacgt
    63721 tagaacccag atagagttca ttgccgagtt tttgacctga taaagcttca gctagctcgc
    63781 ttaccatgag gacaccgtag cggttatccc aagcttttga gatgatattt ttttcattgg
    63841 ctgtcaaaat tgcagaacta tctggtacaa tggtatcacc aggacggatg ccaaaacttt
    63901 ctgcctcagc cttgtccgca aaaccaccat caaaaacgat atcggcaatg gctggcatgg
    63961 ttggtccccc ctttccacga gtcaaatgcg gaggaacaga acctgaaatc acaggaattt
    64021 catgaccatc acgagtcaag agtttgaaac gttggctgct aaccaccatg gggttccagc
    64081 caccgatttc tacgacacgg aaggtaccat ctggcttgat ttcgctgacc ataaaaccaa
    64141 cttcgtccat atgagaagcg accaagacgc gcggtgcatc cacagcttct gaatgtttga
    64201 taccaaaaat accacccaag ccatctgtca ccacttcatc cacatgcggt gtcaactttt
    64261 cacgaagata agcacggaca ggcgcttcat gacctgagac tgcagcaagt tctgttactt
    64321 ctttaatttt tgaaaataat gttgtcattt cagttccttc tttctttcat ccattttacc
    64381 actttttata ggagaaggat agtgggaagg tggatttcta agttagtatc ttagtcctgc
    64441 tctatcttag aaaaggatag tattctcttg catgtagtgc aaaatctagt aaacattcca
    64501 aaattaactc gaatatttat ttccaaacaa aaaaacaata caccatcaaa gttgtttgga
    64561 tttttcatga aatttacaga aaatagttga cttccctttc ttctttcttt aaatatatag
    64621 ttggttgagt ttggaatagt acgctgtagc tgctaaaaca tttctagaaa ttaatttgac
    64681 tttcctaata gagttgttca tatcttattt caatttacta tagtacaaaa ctagaaaagg
    64741 aaaaaatcat gaccaaaaca attcttgtta caggtgggac tagctacatt ggctcccata
    64801 ccgttaaagc tcttttaaat gctggctatc aggtgcatgt cctcgataat ctctccacag
    64861 gaaatcgagc ggctgtggat agtcgtgcta gctttaaaga actggatgtt tatgatgcta
    64921 gcgccttaaa ggcttactta gaagaaaatc agattgatgc tgtcctccat tgtgcaggtg
    64981 aaattgttgt gagcgaaagt attgaaaatc caagtaaata cttcactgcc aacgttgctg
    65041 gtatgaacca agttctcaaa gtcttatctg aagttggcat tcaaaaaatc atgttctctt
    65101 cgactgcttc tctctatgga aataactgta ttgacaagcc ggtgactgaa gataccctgc
    65161 tcgaccctgt caacccttat gcagagacaa aactgatggg cgaacgaatg atttactgga
    65221 tggccaatcg ctacgactgg aaatatgtta ttttccgtta ctttaatgtt gctggggctg
    65281 aaatggatgc ttcaaacggt ctgcgtgtga aaaatccaac tcacatcatt ccaaatatca
    65341 acaagaccgc attgggacaa aatgatagct taaaaatatt tggagatgac tacgatacac
    65401 gtgacggttc atgtattcga gattacattt atgtcttgga ccttgcatag gctcatgtta
    65461 aaggaatgaa ctacctattt caagaagaca gttcttctca aatctttaac ttaggaacta
    65521 aaaaaggcta tactatcaaa gaaatcttta aaactgctga agaattacta aattaaaaaa
    65581 tcccacacga gattgttgct cgacgtgcta gtgacccagc cagtgtccta gcagatgctt
    65641 caaaagctaa acaatatctt gattggacgg ctagctactc cctcgaagat attattttat
    65701 cagattaagg taaaaacatt ttagaatagg ataacaaagg agaaagtctt gttgctctct
    65761 ccttgttgta tttattaaat tgtcagaaat tttattgaca gattagaaaa ataatgttac
    65821 atttatatcc gcaggtatct ttcgatacca aatctacatg aaaggacggg gtatgaaact
    65881 ttctcattat ttaattggct tacttctact cctagtcttt ctctctatta gcattgggac
    65941 cagtgatttt tcatggggaa agctatttga tttcgaccag cagacctggc tcctctttca
    66001 agagtcccgt ctcccaagaa ctatcagtat tctcctgact gcctctagta tgagtatggc
    66061 aggccttctc atgcagacta ttacccaaaa tcagtttgct gcaccgagta cagttggaac
    66121 gactgaagcc gccaaactgg gaatggtgct gagccttttt gtctttccat cggctagtct
    66181 gacccaaaag atgctcttcg cttttatttc atccatcgta ttcaccctct tcttcctagc
    66241 ctttatgacc atttttactg taaaggaaag gtggatgtta cctctgattg ggatcatcta
    66301 tagcgggatt atcggctcag tcacagaagt tatcgcctat cgtttcaatc tggttcagag
    66361 tatgactgcc tggacccagg gctccttctc catgattcag acccatcagt atgagtggct
    66421 cttcttaggc ctcatcatcc tgataaccgt ttggaaatta tcccaaacct tcaccatcat
    66481 gaatctaggg aaagaaacca gcgagagttt ggggatttcc tactccctac ttgaaaaact
    66541 ggccctcttt ctggtggcgc taacgacaag cgtcaccatg attaccgtgg gtggcctacc
    66601 atttctcgga gttatcgttc ccaatcttgt tcgcaagcgc tatggagata atctaagtca
    66661 aaccaaactc atggtcgcac tggttggtgc caatctagtt ctggcttgcg atatcctatc
    66721 ccgagttctg attaggccct atgagttgtc tgtcagtctc ttgctaggaa tcatcggtag
    66781 tctcgtcttt atcctacttc tctggagagg gggacgaaaa gatgcagact aaaagcaaac
    66841 ataccaagct cttctggatt ctcattattc ttgccatcgg agcttgtctt ctctactttt
    66901 ggcccatcac tcacttgtca gcctttgctt ggaagttgcg ttcccaaaag atcatcgttt
    66961 atctcttggt agccatcgcg actgggattt cgaccattag ttttcaaacc ctgacggaaa
    67021 atcgcttcct gacgcctagt attttgggaa ttgaatcctt ctacgtccta ctacaaaccc
    67081 tactactggt ttttgaaagc aagtttcttc aacttggcaa atcccctatc ttagaattcc
    67141 tagtcttact tcttgtccag tccctcttct ttctcgcctt acaaggttac ttgaagacac
    67201 tgatgaagca agacctggtc ttcatcctgc tgatctgtct agcgctcaga agtctctttc
    67261 gaaatatcag caccttcctt caagtcctaa tggatccaaa cgaatacgat aaactgcaaa
    67321 atagtctttt tgcctccttt caacatctta acacttccat cctagccatc ggttctctga
    67381 tcatcctcgc tttgacaatc tttttctttc gaaaagcagt cgttctagat gtcttgcacc
    67441 tgcaaagaga aacggctcag atattgggac tcgatgttga aaaagaacag aaagagctcc
    67501 tctggggaat cgtgcttttg acctcaacgg ccactgcctt ggtaggacct atggccttct
    67561 tcggctttat gctggccaac ctcacctacc tgattgtcaa agactatcag cacaagttac
    67621 tctttatagt ggccattctg gttggattta ttagcttaac cttggggcaa gccttgattg
    67681 aacgagtctt tgcactggaa attcgtatca gtatgatcat tgagagtgtg ggtggcttct
    67741 tattctttat cttactatat aggagggctc gtcagtgaaa ctggaaaaca ttgacaaatc
    67801 cattcaaaaa caggatattt tgcaaggcat ttcgcttgaa gtcagtcctc aaaaactgac
    67861 agcctttatt ggtccaaatg gtgctggaaa atcgactctc ctctccatca tgagcagact
    67921 aaccaagaaa gatcagggag ttctcagtat caaaggacgt gaaatcgaga gctggaattc
    67981 gcaagaactg gcccaagaac taaccatcct aaaacagaaa atcaattacc aagccaaatt
    68041 gactgttgaa gaactggtca gttttggacg ttttccctac agccgaggtc gacttagatc
    68101 agaagactgg gaaaaaatcc gagaaactct gaactatttg gaactgacca acttaaaaga
    68161 ccgctacatc aatagcctgt caggggggca actccagcgc gtctttatcg ctatggtact
    68221 ggcccaggat acggacttta tcttgctgga cgaaccactc aacaatctcg atatcaagca
    68281 aagcgtcagc atgatgcaga ttcttcgacg actggtggag gaactcggca agaccattat
    68341 catcgtcctc cacgatatca acatggccag tcagtatgca gatgaaattg tcgccttcaa
    68401 ggacggccag gtctttagca agggaagaac cgatcaaatc atgcaggctg acctgctcag
    68461 tcaactttat gagattccca tcacgctagc tgatatcaat gacaaaaaga tctgtatcta
    68521 tagctagtaa cataaaagct caagttagag aaccttcagt ctcttagtca ataagattaa
    68581 gagactccct aaatcgttat cacattttaa aaaggagaaa ttatgaaaac atcccttaaa
    68641 ctttatttca ctgccctagt ggccagcttc ttgctcctac ttggtgcatg tagtacaaac
    68701 tcaagcacta gtcagacaga gaccagtagc tctgctccaa cagagataac cattaaaagt
    68761 tcactggacg aggtcaaact ttccaaagtt cctgaaaaga ttgtgacctt tgacctcggc
    68821 gctgcggata ctattcgcgc tttaggattt gaaaaaaata tcgtcggaat gcctacaaaa
    68881 actgttccga cttatctaaa agacctagtg ggaactgtca aaaatgttgg ttctatgaaa
    68941 gaacctgatt tagaagctat cgccgccctt gagcctgatt tgattatcgc ttcaccacgt
    69001 acacaaaaat tcgtagacaa attcaaagaa atcgccccaa ccgttctctt ccaagcaagc
    69061 aaggatgact actggacttc taccaaggct aatatcgaat ccttagcaag tgccttcggc
    69121 gaaactagta cacaaaaagc caaggaagaa ttggccaagc tagacaagag catccaagaa
    69181 gtcgctacta aaaatgaaag ctctgacaaa aaagcccttg cgatcctcct taatgaagga
    69241 aaaatggcag cctttggtgc caaatctcgt ttctctttct tgtaccaaac cttgaaattc
    69301 aaaccaactg atacaaaatt tgaagactca cgccacggac aagaagtcag ctttgaaagt
    69361 gtcaaagaaa tcaaccctga catcctcttt gtcatcaacc gtacccttgc catcggtggg
    69421 gacaactcta gcaacgacgg tgtcctagaa aatgccctta tcgctgaaac acctgctgct
    69481 aaaaatggta agattatcca actaacacca gacctctggt atctaagtgg aggcggactt
    69541 gaatcaacaa aactcatgat tgaagacaca caaaaagctt tgaaataagc cacttcaaac
    69601 tcaatttaat actcaatgaa aatcaaagag caaactagga aactagccgc aggttgctca
    69661 aaacactgtt ttgaggttgc agatgaaagc tgacgcggtt tgaagagatt ttcgaagagt
    69721 ataaaatttt gacattctaa aacgcatcct atcaagttca ctcaaacctg ataggatgcg
    69781 tttttatcat tttgaaatct atttacccca cctcattccc cttcttgatt tcgtttaagg
    69841 gaaaagtggt ctggaacggg gtccttacct gttttcgacc agggatgaca acgtaaaatc
    69901 cgagccaagc ccatcaatac ccccttaaaa ccatgttttt caatagcctg aatcatgtag
    69961 ttggaacaag tcagctcaaa gcgacaagag ggtggaaaga ctggtgagat aaaacgttgg
    70021 taaaagcgca caggcgctat taaaattcgt ttcattattt cttagttaca gccatggtgt
    70081 gtagttggct gatttctttt ttattaagac gacgggattc tcctggacgg agtcctgtca
    70141 agtctaggtg tccgaaacga gtccgagaca acttatctac ttggagacca acagcttcaa
    70201 acatcttttt aacttgatgg ttacgccctt catggatggt caactgcacc acagagcgat
    70261 ttttgactgg gtccactttg agaatttcat aaacagctgg cttggttttc ttaccatcaa
    70321 tctcaagacc acgggtcaag gggcgaagat tgtccttatt ggtcacacct ttaacacgcg
    70381 ctacataaac cttgtcaatc tcattacgag ggtgaatcat ctcgtctgta aagtccccat
    70441 cattggtcaa aatcaagact cctgatgtat cccagtccaa acgacccaca gggtaaatgc
    70501 gctctttgac attgggcaag aggtcgacaa ccgtcttgcg acccttgtca tctgttacac
    70561 tggaaatgac accgcgtggt ttgttaagca gataatagac cttttcttcg ttgtagatag
    70621 gttgaccttc aacttcaacc ttgtcgcctg acttgatagt ggttgctagt tcacgcacca
    70681 cttggccgtt aaccgtcacc aaaccttgct tgatcagctc ttctgctttt ctcctactgg
    70741 ccacacctgc gtgggcaata tacttattga ttctcatctt cttctatcct ttcaccaaat
    70801 aattggcttt cttgggcttg aatctcaagc tcatcaatca ctggtaattc ttctaaatgg
    70861 tttatcccca tgtaatctag gaaataatcc gtagtcacat agaggttggg gcgccccaat
    70921 acttcctttt tcccgtcttc ctttatcagg tcaaaagctt gcaactttgc caaggctcca
    70981 ctcgagttaa ccccacggat ggcatcaatt tctatccgcg taatcggctg tttgtaggca
    71041 ataatggaca aggtctcaag ggcagcccga gacaagctct ggttgatagg cgccttagag
    71101 tattccttca aaatctctgc aaattgaggc ttggtcacca atctataagc accacttgtc
    71161 tcaatcaaag ccaaactgga atctgggtcc ttttcatact tctgggctaa ttttcctaaa
    71221 ctctgctgga tgcctgtcgg tggcagagag aggagttcag ctaactggcg gacccgaatc
    71281 ccatcttcac ccgctacaaa caagagcgct tctatttttg ctaaagtact catctttcct
    71341 ctctatcaag tctagctttg aggcacttga ctttcttcct tcttttccat gagatagata
    71401 tctccgaaac tctcctcttg cacgaggatc agctcctggg ttttgattaa ctctagggtt
    71461 gccaaaaaga gggtgatgac ctcttggaca ttctgggctt ccttgaacaa atcctgcaag
    71521 cgcaattgat ctcgtccaat caaggattct ttcacaataa tcatcatgtc ctcaatctta
    71581 tactcatccc gcaagatagt cgtgtgattt tgtgcaaact cctctttttt cttggctagg
    71641 atatttgaaa aagccaaaaa gaggtcaatg gtcgtcttgt catgcacaag ctccgcatct
    71701 tcgtaaatca actctgtcgg cgctttggaa taatactggg cccgttcttg gtgcttggct
    71761 tccaagtgct cacccaagag cttgaacttg cgatattctt cgatttgaga gaggaggtcc
    71821 tgctccaggt catcccccaa gtctgtcact tctgctacct tcggaaggag tttacgactc
    71881 ttaatcagca tgagctgact agccatgacc atgtactcac ccgtcacttc cagacgcatg
    71941 gcctgcaggg ttgagacata ggctagatac tgttcgatga cttccgtaat gggcacatcg
    72001 tagatatcca tctggtactt agaaaccaga tgcaagagca agtccagggg tccttcaaaa
    72061 tcttttaatt taatatccat tatctatatt tttctaaggt caggactgtt tttaatccta
    72121 atttttttgc aatttcgtac aaatcgacct tgttttctat ttgtcttaga ataaactgtt
    72181 cacgtaagac ttgagctgat aaggatggaa aacctttctc cttgacaaaa gattctaact
    72241 gacgaaaggc ccactgacga gaatagggtt tctctcctct ttcaaaaaga taggtctgcc
    72301 ccatcaaggg ttccaattct gaaagcaagg ccgtgggaat ggtgacaatc ctctgttggg
    72361 aagccttgct gattcgcagc acctgaaaat ccagattgat gtccgcaacc ttgatggcta
    72421 aaatctcact aggcaagagc cccatttcta ggattaagag cgctagcaag cggccctctg
    72481 gatggtcgct ttcctgccaa aaagagtcta ggtatagaat ctctggcttt tccgtcttct
    72541 tttcagcttg tttggctaat tccaagcggt aaaagctgtc cacctctcct ttttgataga
    72601 gaaagtatag aaattggtta caggccgaaa tctttcgctt ctgggcgctg atttttagat
    72661 tggctagctg ggcttggtaa atcttgagac tggtctcaga aatccgctca cctaccatgt
    72721 ctaaaaattg ctccaaatca tacttatagg actgcttgga attgacagac aagccctgct
    72781 tttcctctaa aaaggctgaa atcctgtctc tcattggcat cgaatctcat attccttact
    72841 aaagtcatgc aagagggcat taacggcctt gaggatggac ttgcgcgtaa taatcccttg
    72901 gaaaataccc tctgcatcca caaccggtaa gaaggactca tctactagct tgtgcaagac
    72961 ctccgtaatg gtgaaatcag gcgaaacaac cgctacgtcc gtttttgtca tatgaacgat
    73021 atccgtatcc gccatgattt cttggctcaa gtcatgctcc atctgataag ccataatatc
    73081 tctgagtcca atcgtcccaa caaactgttt ttcatctgtc acaacgggaa cacgggtata
    73141 ggtcatctga ctgagcaaga gggtcgcatg atccgcattg tgggtatcaa tcaacacagc
    73201 tagattttta gcaggggtca aaaaagtttc ctcctgcccc aacaagaaag tctcaaactc
    73261 cttggcaatc atcggctaaa ctccttggac aaacctggat acacctcgtg atctcgtgtc
    73321 aaaaagtcca ctttgaagta actatcatca atctccacac gagcatagag acattctctg
    73381 atggtacctc gtggttgact gatagaacct ggatttagaa agaggatctt gccttccaac
    73441 caagcacttg gcacatgcaa gtgaccatag aggcagatag cggcctcttc ctcctgagcc
    73501 cagtagtcca acttttgaaa gttgaaattg atgtcaaaca agtgaccatg agtttggata
    73561 atcttggtcg aaccaagctc agtcaccaga cgttctgggt agccggcgta gaagtccatg
    73621 ttccctttaa caacgcggat gccctcccaa agtggagaat ccggacgtag ttcagaatcg
    73681 ccgttatgaa aaacggcatc gactttgccc acatagcgat cacggacttc ttccacaatc
    73741 aagctatcgc catgggaatc gctcattaca atgatggttt gctttgccat gatggaaata
    73801 cctccaaaag tttcttaacg gctaaggcac ggtgagattg actatttttt tcttccaggg
    73861 ttaattcagc tgatgactca cctgtttctc ctacaaggaa gaggggatca tagccaaagc
    73921 cattttcacc cttaggttca aagttaatat aacctgacca gtctgcttca acaactaaac
    73981 tttccttatt tgggctggct acgactaggg ttgtgtggaa ctgagccgag cggtccttga
    74041 gttcaaagac catggccaat tcgtgcaaga gtttggcatt attttcacgg tcagttgctc
    74101 ccacacctgc gaaacgagct gaccagacgc ctggtaagcc accaaggaca tcgactttga
    74161 gaccagaatc atctgccaaa accatcttgc ccgttaattg agaaatggtt tctgccttaa
    74221 ggcgggcatt ttcttcaaag gtcatacctg tttctgctac ttcaggcagg tcagggtagt
    74281 cattaagatt ttccacatcg tagcctaact tatcaaagat agctcgaaat tccttggttt
    74341 taccttcgtt acgagtcgca atcaacaagg tttctctgac cttgcttgtc tcaaagaaat
    74401 catgaacatt gaccccttct ttaggcaatt ctacatacaa gagttgccca ttttcaacca
    74461 agagcagggc cccatgacgt tgaataactt ccaagtttcg tcccatttct tgattaagca
    74521 tgtctaccac aaaggagaac aaacggtagg tagaaccata gcgtaaaaca gtaactgaaa
    74581 gcgggaaacc atactcttca tctccaaata ttttggagaa ttcaaacaga ggaaaatctg
    74641 tcttatagtc gctcaaactg ttaacgccac caaaaatact ataagaccca acataccagt
    74701 cctggtcatc cttatattca taaattttat ttgtcataat tctacatgct ccacatgaat
    74761 ctctttttcc agccattctt caccaatttg tgcaaaactt tggctactgg ctgttgtgta
    74821 aaaacggtga tggagtggtc cagcatcgcg accacgattg atttcaaaat aattgagtaa
    74881 gactgagata tcccgtacgc actctgcccc actatcgatg agctgaacct ttggccccat
    74941 cacattttgg ataatagggc gaaggagtgg ataatgagta cagcccaaaa tcaggctatc
    75001 cacctttcca accaagggac gcagggtttc atagaccacc ttcttggtaa cactggttga
    75061 cagggcacct gactcaacca agggagcaaa cttgggacag gccaagctct ccacctgtaa
    75121 gtcgggatcc agatcatgga ttttcttacg gtatatgtct gattgtaccg tcatgggcgt
    75181 tccaatcact ccgattttcc caccttgact ggacttgatg gctgccgaag ctcctggcaa
    75241 aattacaccc aagacaggaa tatctagttg agccttgatt tcttcccaga cgaccgcagt
    75301 cgcagtgtta caagcaatga caatcatttt gacatcctta gtcaagagaa agttgaccag
    75361 ctgccgagta tattcacgaa tttgctcagc aggacggggg ccatagggcg cccgcgccga
    75421 atctccaata tagacgattt cttcatgggg aagctggcgc atgagctcgc gcacaacggt
    75481 caagcccccg acacccgaat ccaaaaaacc aattggtcga ttatccatac agtcttcttt
    75541 ctagtctttt ttctgattga tcgttcatta tgattccttg tactgaacga actgaccgac
    75601 agcttgatag aatgtcaact acctctctct taatcataat caaatatcaa tagaatgcaa
    75661 ggaaaaagtc tcatccctaa accataacca acatagtgag aagtctggaa ctttcatccc
    75721 agacttttcc ttatttattt tttcttttta ttgttagcaa gggctgcctt ttgttggcgg
    75781 atgatttggt ggtaaacttg ttgtacctta gcttcgcttg gtttttgacc atttgcactc
    75841 aaaagagtac gaactgcttc agcattcaaa cgtgggttgt cagcaaattc tttttcgatt
    75901 tgcttacgaa ccaagtacat tcctccaaga gctcctccta gaaaagctag cacaatcaat
    75961 acaattgcta aaagtaaatc catcattttt ctcctgtttc tttttgagtc cctttcatta
    76021 taccacaaac tagccaccct gaccagtttg ttctacactt tcagggatgg aatagacagc
    76081 aaaaagaacc ctgcttttct gaaaaagagg tctccttgct aagtttatac tcaatgaaaa
    76141 tcaaagagca aactaggaag ctagccacag gttgctcaaa gcaccgcttt gaggttgcag
    76201 ataaaactga cacggtttga agagattttc gaagagtatt aatttacata aatagccagt
    76261 gtttgatagg gtttgagtag aattttctca gacacttctg catcttcata gtttgatatc
    76321 aaaatctgtc cattttggta gactgctggc aagtcgattt ccacttcttt agcataaaag
    76381 ttattgagca ctagtaactt ttgatcctca aactggcgtt caaaagcgta gacttgtttg
    76441 ctatcttcaa aggctggttt gtaacttcct tctgaaatga ttggcatttc cttacgcagt
    76501 cgaatcaagt cttgatagaa ggtaaaaatc ggaccctgga tttcattttc tacattgatg
    76561 tatttatagg atttaccagc tttcaaccaa ggagtgcctg ttgaaaatcc tgcattttcc
    76621 gaagcatccc actgcatggg aatgcgtgaa ttatcacgcg acttagcttg aataatctgg
    76681 aaggcttctt gctgactctt tccttcttct aagagcatct gataggcatt aagcgattcg
    76741 acatccacat aatcagccat agaatcatag tctgggtcaa tcatcccgat ttcctcaccc
    76801 atgtagatat aaggtgtccc acgtgacagg tgaatgctgg ctgctagcat ggtggctcct
    76861 tccttgcgga agttttgaat atcgacaaaa cggttcaagg cacgtggttg atcgtgattg
    76921 ttccaaaaga gggcactcca accgtcttta tcactcattt ccttacccca actatggtaa
    76981 agactcttca actcttcaaa atcaaaggga gccaaggtcc acttttgtcc atccttatag
    77041 tccaccttga ggtgatgaaa attaaaggtc atggataatt cctgacgatc aggcgacgaa
    77101 tagaggacac agttttccat ggtggtagaa gacatttccc caactgtcat aaagctatcg
    77161 tcagatccaa aagtggcttg gttcatcata cgcaaatagt tatgaacgat gggtttgtct
    77221 gtataagctg gcttcccttc attttcagga cagtccactg aaacctcgtc cttaccgatc
    77281 aaattgatca catcaaatcg gaaacctttg acacccttgt cgcgccagaa attaacaacc
    77341 ttgaaaagct ccttacggac attggaattg cgccagttaa ggtcagcctg ggtctcatca
    77401 aataggtgaa gatagtattt cccagtatcc ccgaaaggcg cccatgcaga accaccaaac
    77461 ttagactgcc aatctgttgg ttggtcttgg atgaagaaaa agtcttgata atacttatca
    77521 ccagctaggg ctttctgaaa ccattcatgc tctgtcgaac aatgattaag taccatgtcc
    77581 agcataaagt caatcttgtg ctctttaccg acacatacca tttcctcaaa atcagccata
    77641 tcaccaaaaa gaggatccac tgccatataa tctgaaatat cgtaaccatt atcccgttga
    77701 gggcttggat agaatggatt gagccagacc atatccacac ctagtttggc taaataggga
    77761 attttttcga taatcccacg gaaatcccca ataccgtttt cagtggtgtc tttgtaagat
    77821 tttggataga tttgatagac tacttttcct ttatcaagtg tcatctgttt ctccttttct
    77881 gataaaaggg aggaagcagt cttccgtccc tatttgtgct atttcaatta tactcaatga
    77941 aaatcaaaga acaaactagg aagctagcca caggttgctc aaaacactat tttgaagttg
    78001 cagatagagc tgacgtggtt tgaagagatt ttcgaagagt attagattcg tgtagcgacc
    78061 atgagagatg ctccagcttg gatcgttgtc ggataagttc cgggaatagt cactgtataa
    78121 gcatcttggt tggtgatgat aacaggagtt tctgtcacca gacctgcagc cttaatgaca
    78181 tccatatcaa aacgaatcag ttgctgacca actgtaacgt gatctccttg gactacaaga
    78241 ctttcaaaac ctttgccatc aagacctact gtatccatac cgatgtggat gagcaattca
    78301 actccctcgt cagagacaat gccgatggca tgcttggtag ggaaaagaac cgtcactgtc
    78361 ccattaactg gagaggtcaa ctcaccttgg cttggttcaa tgactagacc ttgccccatg
    78421 acacctgatg caaaaatagg atccgtcgct tgactcaatt ctttcacttg gccagttagt
    78481 gggctgataa tttctaccga agtaagttct actggttcat ggttcacaaa ttctgcttct
    78541 tcttgagcaa cgaattctgc ctgcaagttc gtatcgccct ctgtttttgt aaagagacca
    78601 gccttgcgga agaagaaagt caagagcatt ggaacaacaa tcgcaactag catagttcct
    78661 gcaaatggca gcatgtattg aggttgaata gagagaatac ctggcaaacc accgatacca
    78721 atagaagccg cagttacatt aaaagtaacg gataacatgc ctgcaagggc tgaaccagtc
    78781 atcccagcaa caaatggata aatatatttt acgttaaccc caaaaagagc tggttctgta
    78841 acaccgagat aggctgaaat ggttgcagga agtgaaacct gagcctcacg ctcatcatgg
    78901 cgatgcatga aataataggc aaacacggct gagccttgag caatattaga aagagcaatc
    78961 attggccata gggcagtgcc accagcatcc gcaatcaatt gtgtatcaat ggcattggtc
    79021 atatggtgca gacctgtgat gacaaatgga gcgtagaggg cgccaaaaat tgcaccgaag
    79081 agccatttaa ctggaccagt taaacctgcc aagacaactg atgaaagtcc ttgtccaatt
    79141 gtccaaccga ttggtcccaa aacagtatga gccaaaatca aggctggaat caatgacaag
    79201 aaaggtacaa aaatcataga aatgacttct gggatatgct tgcgccagaa gatttcaaga
    79261 taagacagac tcaaacctgc aagcaaggct gggataactt gggcttggta accgatacga
    79321 ttaacagtaa aatagccaaa attccaaacc cagtttgccg cgatatcagc tgctggcgtt
    79381 gaagcaaccg cataggcatt gagcaactga ggcgatacca aacagattcc gagaacaatt
    79441 cccaaaattt ggctggttcc catcttacga gaaacagacc aagtaatccc tactggtaag
    79501 aactggaaga tagcttcacc aggcaaccag aggaagtgat tgacacctgc ccaaaactga
    79561 gaggattctg tgatggtctt gccatccaac atcgaccaat ggacaccttc caagacatta
    79621 cggaaaccga ggatcaatcc tccgactatc aaggctggaa taatcggagt aaaaatctcc
    79681 gccagagtgg tcataacacg ttggaccacg ttttgattac tcttagctgc agacttggct
    79741 gcttctttgg aaacaccctc aatacctgaa acggctgtaa aatcattata aaagatgggc
    79801 acgtcatttc caatgattac ctgaaattga cctgcatttg taaaggttcc tttaacagct
    79861 ggaattgact cgatagcttt aacattagcc ttcttatcat ctcctaaaac aaaccgcatc
    79921 cgtgtcgcac agtgagttac ggcagtcaca ttttctttgc ctccgattgc ctgaagcaga
    79981 tctttggctt cttgttcaaa ttttcccatt tgattctcct tatacttgtc aaagcaagtt
    80041 tgatttgata agtatattgt aaacgatacc aaacttgtct gcaacttgtt tggtataaaa
    80101 agggtgtttt tttgtaaatt ttctagcact tgtatggtaa aatagataca ggtgttcatt
    80161 aaactagact aaaaacctat ttaagcaggc aaaatgaaga aataccaaca attatttaag
    80221 caaatccaag aaaccattca aaacgagact tacgctgtcg gagatttcct tcctagcgag
    80281 cacgacctta tggagcaata tcaagtgagt cgtgataccg tccgaaaggc cctgtctctc
    80341 ctccaagagg aaggattgat caaaaagata agagggcaag gttctcaagt cgtcaaagaa
    80401 gaaaccgtca atttccctgt atccaaccta accagctacc aagaactagt taaagaactt
    80461 ggactgcgct ctaaaaccaa cgtggtcagt ctggacaaga ttattattga taaaaaatcc
    80521 tcactgataa ccggtttccc agagtttcgg atggtttgga aggtggtccg ccagcgtgtg
    80581 gtggatgatc tggtatccgt tctggatacg gactatctgg atatggaact catcccaaat
    80641 ctcactcgcc aaattgctga gcagtctatc tattcttata tagaaaatgg cctcaaactc
    80701 cttattgatt atgctcagaa ggaaatcacc attgaccact caagcgaccg agacaagatt
    80761 ctcatggaca ttggcaaaga cccttatgtc gtttcgatta aatcaaaagt ctatctccaa
    80821 gacggacgcc aatttcagtt taccgaaagt cgccataagt tagagaaatt tagatttgta
    80881 gattttgcaa aacgcaagaa ataaaagact gagacaccag atctcagcct ttttcggctc
    80941 tataatattt gtagtgggta acccccctat ggatattatg gagcctattt tgtgtagaaa
    81001 aaaagtccca tatgacctat
//
LOCUS       DBERPV010000006        75824 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.06, whole genome shotgun sequence.
ACCESSION   DBERPV010000006 DBERPV010000000
VERSION     DBERPV010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 75824)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 75824)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..75824
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.06"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            395..1741
                     /gene="gdhA"
                     /locus_tag="ACL8C7_000548"
     CDS             395..1741
                     /gene="gdhA"
                     /locus_tag="ACL8C7_000548"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HGS1394805.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGSVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSNLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGVV"
     gene            complement(2030..5608)
                     /locus_tag="ACL8C7_000549"
     CDS             complement(2030..5608)
                     /locus_tag="ACL8C7_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGS1394806.1"
                     /translation="MSLRNKIEQHIKELEGGKFQKLGDAYLSRKYNFNIVSLGSQEGT
                     DKTTKGIPDSYAVENGKYVYIMYGTHKSVISKLEGDIQSVKKKILEENIAEDKVGRLI
                     CCHTSSNITIKQKEDLEKMAEPYHLELIGINEIANDLTKIDFQYLAKEYLSISESTEQ
                     VWSINDFIRIHDESKTNAPISNDYIGDVSEIINTIKSSEKRIFLISAKPGTGKTRLAI
                     EICSLLDRNKYNIICVKSNNQDIYQDVKRNLNLHKENIIFIDDVNTTQNYISTLGLLN
                     TTSNIRFILTVRDYAKKDVINNIKVYGYNNIEPELIKDDNFKELLNQFSRNDFTNQEI
                     EHIKTISKSNPRIAVIAAKLSSSQDLTNFNDEIDILKDYYEEILNKNNIIYAEQKTLF
                     ILSYLKKIRLESLEENQEFNKLLKITDITNTDFKSAVEKLHERELCNIYNDKIVKIAD
                     QSLDDYIVIKFLINKKISILEILHELYPVNDQRVVQILNQCSNFIRKESDLEGVSDAV
                     KSYYYNESNFESDELKEKFLIQFGVLLPLEAISHVKNKIDNIESQVYTKTNFINQKDK
                     KGSIEDSVLNIVFVTTRTKYCSQILQLLLKYFDKNPNKISEVYSILEANYGLVTEREY
                     IDYTLAENTISELANLDLTKSYNQELIVTILKQFLKIEIERTEAHEEKFTFGRYKVPD
                     SEKLKQYHRSILKLLANLYNIGSCETRFYIEKMLYDYRRKILTYSESHRNTIFGDLRN
                     IRKLFFNDIKNLSMIGEKIVYALHKAEVKENLPIVFDDYIISDRQKIYNNLTNPNHAW
                     FYDASEIKLQQIANSYSNVWLKIFNFANQFKHSLFMNDNNIELVLFNMFLLSKNDKKI
                     KFLNYMFKSNYHFVNMNPISFLENIEESSMQSVIVSSPESEKYEWQLAYLTQLENVKN
                     EDLQTLKSILEANSLPCYFTILNFERLILKDPSLKELLIQKAGNTNFVISDFIREEEV
                     PKLINLIGVKELKFWYLINLENCQNHSYNLFQKLGEKDVDFSVEVLKKIDELRIGHSN
                     LGYMVLHSISEFRDKKEIYKKFIRFAINRPYYYYNNMIDDIIKNDSQIILEILEETNN
                     EQSAIRLVNLGVEFLENNNQKLILFNLLRAKGFGKKSFQEIHFTPYSHFYTGSHVPVL
                     ELEKELLERIKKIFETGIDYINLLLYLNKLIDCKRKAIERELEKEF"
     gene            complement(5856..6224)
                     /gene="rplL"
                     /locus_tag="ACL8C7_000550"
     CDS             complement(5856..6224)
                     /gene="rplL"
                     /locus_tag="ACL8C7_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HGS1394807.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            complement(6300..6800)
                     /gene="rplJ"
                     /locus_tag="ACL8C7_000551"
     CDS             complement(6300..6800)
                     /gene="rplJ"
                     /locus_tag="ACL8C7_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HGS1394808.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     misc_feature    complement(6839..6974)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(7050..8309)
                     /locus_tag="ACL8C7_000552"
     CDS             complement(7050..8309)
                     /locus_tag="ACL8C7_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HGS1394809.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKALGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     gene            complement(8490..10238)
                     /locus_tag="ACL8C7_000553"
     CDS             complement(8490..10238)
                     /locus_tag="ACL8C7_000553"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1394810.1"
                     /translation="MKRQTVNQTLKRLAVDLASHPFFLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAYDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKELSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHCLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            complement(10240..11964)
                     /locus_tag="ACL8C7_000554"
     CDS             complement(10240..11964)
                     /locus_tag="ACL8C7_000554"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1394811.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKGELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFVEAPEDIHSELEQKQATRDKVLQV
                     QELTFTYPDAAQPSLRYISFDMTQGQILGIIGGTGSGKSNLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQELWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            complement(12022..12960)
                     /gene="msrB"
                     /locus_tag="ACL8C7_000555"
     CDS             complement(12022..12960)
                     /gene="msrB"
                     /locus_tag="ACL8C7_000555"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HGS1394812.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKTSLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            complement(13210..14079)
                     /gene="thrB"
                     /locus_tag="ACL8C7_000556"
     CDS             complement(13210..14079)
                     /gene="thrB"
                     /locus_tag="ACL8C7_000556"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004413 - homoserine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HGS1394813.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(14081..15367)
                     /locus_tag="ACL8C7_000557"
     CDS             complement(14081..15367)
                     /locus_tag="ACL8C7_000557"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HGS1394814.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(15518..16255)
                     /gene="mecA"
                     /locus_tag="ACL8C7_000558"
     CDS             complement(15518..16255)
                     /gene="mecA"
                     /locus_tag="ACL8C7_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HGS1394815.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFAEDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(16455..17489)
                     /locus_tag="ACL8C7_000559"
     CDS             complement(16455..17489)
                     /locus_tag="ACL8C7_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HGS1394816.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPEDSAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(17518..18951)
                     /locus_tag="ACL8C7_000560"
     CDS             complement(17518..18951)
                     /locus_tag="ACL8C7_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HGS1394817.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            complement(18967..19953)
                     /locus_tag="ACL8C7_000561"
     CDS             complement(18967..19953)
                     /locus_tag="ACL8C7_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGS1394818.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFKAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(19955..21058)
                     /locus_tag="ACL8C7_000562"
     CDS             complement(19955..21058)
                     /locus_tag="ACL8C7_000562"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGS1394819.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYTSKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(21048..21893)
                     /locus_tag="ACL8C7_000563"
     CDS             complement(21048..21893)
                     /locus_tag="ACL8C7_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGS1394820.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKNFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDTVIADMDKSYTEYK
                     GEYGG"
     gene            complement(22172..23446)
                     /gene="psr"
                     /locus_tag="ACL8C7_000564"
     CDS             complement(22172..23446)
                     /gene="psr"
                     /locus_tag="ACL8C7_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HGS1394821.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDTYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(23443..24291)
                     /gene="pheA"
                     /locus_tag="ACL8C7_000565"
     CDS             complement(23443..24291)
                     /gene="pheA"
                     /locus_tag="ACL8C7_000565"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HGS1394822.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     NYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(24288..24764)
                     /locus_tag="ACL8C7_000566"
     CDS             complement(24288..24764)
                     /locus_tag="ACL8C7_000566"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HGS1394823.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIENRLGMSIANFFA
                     EKGETAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLRADFETLY
                     QRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(24757..26040)
                     /gene="aroA"
                     /locus_tag="ACL8C7_000567"
     CDS             complement(24757..26040)
                     /gene="aroA"
                     /locus_tag="ACL8C7_000567"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HGS1394824.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLINPNSHLVLQNVGINETRTGIIDVIRAMGGKL
                     EVTEIDPVAKSSTLTVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVDLDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(26132..26470)
                     /locus_tag="ACL8C7_000568"
     CDS             complement(26132..26470)
                     /locus_tag="ACL8C7_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HGS1394825.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(26481..27584)
                     /locus_tag="ACL8C7_000569"
     CDS             complement(26481..27584)
                     /locus_tag="ACL8C7_000569"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HGS1394826.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLESIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITKNTDYTVVIK"
     gene            complement(27594..28760)
                     /gene="aroC"
                     /locus_tag="ACL8C7_000570"
     CDS             complement(27594..28760)
                     /gene="aroC"
                     /locus_tag="ACL8C7_000570"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HGS1394827.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(28770..29837)
                     /gene="aroB"
                     /locus_tag="ACL8C7_000571"
     CDS             complement(28770..29837)
                     /gene="aroB"
                     /locus_tag="ACL8C7_000571"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HGS1394828.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTELNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKTRGNTLKLVLVS
                     ELGSAIIHPVSLEEMKDYLVK"
     gene            complement(29856..30710)
                     /locus_tag="ACL8C7_000572"
     CDS             complement(29856..30710)
                     /locus_tag="ACL8C7_000572"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HGS1394829.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(30700..31377)
                     /gene="aroD"
                     /locus_tag="ACL8C7_000573"
     CDS             complement(30700..31377)
                     /gene="aroD"
                     /locus_tag="ACL8C7_000573"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HGS1394830.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQFYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(31374..32537)
                     /locus_tag="ACL8C7_000574"
     CDS             complement(31374..32537)
                     /locus_tag="ACL8C7_000574"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HGS1394831.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQTFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(33222..34856)
                     /locus_tag="ACL8C7_000575"
     CDS             complement(33222..34856)
                     /locus_tag="ACL8C7_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394832.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMIICFSNIAIHFPFEEIPIYFSSMIAILLVIAFSTSLTAFYNVFYESK
                     DLISYRPYTFKESEIIIAKGLSVLLPALTGIVPILAYFLVLYIRLAPSLWLGLPLMLL
                     SLTLLFVSVALVMVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEAILGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKFKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFFPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIYAVQSFLPVLTLLGLSLYLGLPIISMIYLIVAWILASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLST
                     ILAISLGVGALILLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(34837..35586)
                     /locus_tag="ACL8C7_000576"
     CDS             complement(34837..35586)
                     /locus_tag="ACL8C7_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1394833.1"
                     /translation="MIEFQNVSKLYGDKKALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVED
                     LRKDYPDQSLESIYLSLAGRKEEVADASQGH"
     gene            35765..37219
                     /locus_tag="ACL8C7_000577"
     CDS             35765..37219
                     /locus_tag="ACL8C7_000577"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004556 - alpha-amylase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HGS1394834.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGNNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHTNCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(37309..39927)
                     /gene="alaS"
                     /locus_tag="ACL8C7_000578"
     CDS             complement(37309..39927)
                     /gene="alaS"
                     /locus_tag="ACL8C7_000578"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HGS1394835.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNHNASQLSSKLVAIVADNAEVEAVSEGTTSLIFAETPFYAEMGGQVA
                     DHGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQPKIQELLDAVAGKL"
     gene            complement(39949..40434)
                     /locus_tag="ACL8C7_000579"
     CDS             complement(39949..40434)
                     /locus_tag="ACL8C7_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HGS1394836.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(40709..40948)
                     /locus_tag="ACL8C7_000580"
     CDS             complement(40709..40948)
                     /locus_tag="ACL8C7_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394837.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTVILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(41201..42271)
                     /locus_tag="ACL8C7_000581"
     CDS             complement(41201..42271)
                     /locus_tag="ACL8C7_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS1394838.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGMENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(42268..43041)
                     /locus_tag="ACL8C7_000582"
     CDS             complement(42268..43041)
                     /locus_tag="ACL8C7_000582"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1394839.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(43038..43844)
                     /locus_tag="ACL8C7_000583"
     CDS             complement(43038..43844)
                     /locus_tag="ACL8C7_000583"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1394840.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWIMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(43825..44982)
                     /locus_tag="ACL8C7_000584"
     CDS             complement(43825..44982)
                     /locus_tag="ACL8C7_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1394841.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRNIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNELVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(45143..46048)
                     /gene="murB"
                     /locus_tag="ACL8C7_000585"
     CDS             complement(45143..46048)
                     /gene="murB"
                     /locus_tag="ACL8C7_000585"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HGS1394842.1"
                     /translation="MSVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(46160..46912)
                     /locus_tag="ACL8C7_000586"
                     /pseudo
     CDS             complement(46160..46912)
                     /locus_tag="ACL8C7_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
     gene            complement(46922..47653)
                     /gene="budA"
                     /locus_tag="ACL8C7_000587"
     CDS             complement(46922..47653)
                     /gene="budA"
                     /locus_tag="ACL8C7_000587"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HGS1394843.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELEERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     VGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            47795..49066
                     /locus_tag="ACL8C7_000588"
     CDS             47795..49066
                     /locus_tag="ACL8C7_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HGS1394844.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLSLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(49086..49901)
                     /locus_tag="ACL8C7_000589"
     CDS             complement(49086..49901)
                     /locus_tag="ACL8C7_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS1394845.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVDAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLNMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(50058..50711)
                     /gene="phoU"
                     /locus_tag="ACL8C7_000590"
     CDS             complement(50058..50711)
                     /gene="phoU"
                     /locus_tag="ACL8C7_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HGS1394846.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(50723..51481)
                     /gene="pstB"
                     /locus_tag="ACL8C7_000591"
     CDS             complement(50723..51481)
                     /gene="pstB"
                     /locus_tag="ACL8C7_000591"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGS1394847.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDRTG
                     FFLDGDLIEFNDTKQMFLNPQHKETEDYITGKFG"
     gene            complement(51494..52297)
                     /gene="pstB"
                     /locus_tag="ACL8C7_000592"
     CDS             complement(51494..52297)
                     /gene="pstB"
                     /locus_tag="ACL8C7_000592"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGS1394848.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(52308..53192)
                     /gene="pstA"
                     /locus_tag="ACL8C7_000593"
     CDS             complement(52308..53192)
                     /gene="pstA"
                     /locus_tag="ACL8C7_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HGS1394849.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(53182..54099)
                     /gene="pstC"
                     /locus_tag="ACL8C7_000594"
     CDS             complement(53182..54099)
                     /gene="pstC"
                     /locus_tag="ACL8C7_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HGS1394850.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGIWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(54099..54977)
                     /gene="pstS"
                     /locus_tag="ACL8C7_000595"
     CDS             complement(54099..54977)
                     /gene="pstS"
                     /locus_tag="ACL8C7_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HGS1394851.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(55551..56855)
                     /locus_tag="ACL8C7_000596"
     CDS             complement(55551..56855)
                     /locus_tag="ACL8C7_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HGS1394852.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(56856..57629)
                     /locus_tag="ACL8C7_000597"
     CDS             complement(56856..57629)
                     /locus_tag="ACL8C7_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HGS1394853.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGHLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(57619..57897)
                     /locus_tag="ACL8C7_000598"
     CDS             complement(57619..57897)
                     /locus_tag="ACL8C7_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HGS1394854.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYESKVEAKKLLDS
                     YKGFKEVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(57897..58298)
                     /locus_tag="ACL8C7_000599"
     CDS             complement(57897..58298)
                     /locus_tag="ACL8C7_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HGS1394855.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(58508..59125)
                     /locus_tag="ACL8C7_000600"
     CDS             complement(58508..59125)
                     /locus_tag="ACL8C7_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HGS1394856.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYENFFGYLYLKSRRK"
     gene            complement(59115..59888)
                     /locus_tag="ACL8C7_000601"
     CDS             complement(59115..59888)
                     /locus_tag="ACL8C7_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HGS1394857.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(59899..60636)
                     /locus_tag="ACL8C7_000602"
     CDS             complement(59899..60636)
                     /locus_tag="ACL8C7_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HGS1394858.1"
                     /translation="MCLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKV"
     gene            complement(60641..61771)
                     /gene="hemW"
                     /locus_tag="ACL8C7_000603"
     CDS             complement(60641..61771)
                     /gene="hemW"
                     /locus_tag="ACL8C7_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HGS1394859.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(61855..62244)
                     /locus_tag="ACL8C7_000604"
     CDS             complement(61855..62244)
                     /locus_tag="ACL8C7_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HGS1394860.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(62217..62643)
                     /locus_tag="ACL8C7_000605"
                     /pseudo
     CDS             complement(62217..62643)
                     /locus_tag="ACL8C7_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895042.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
     gene            complement(62644..63432)
                     /gene="lgt"
                     /locus_tag="ACL8C7_000606"
     CDS             complement(62644..63432)
                     /gene="lgt"
                     /locus_tag="ACL8C7_000606"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HGS1394861.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFSLRVSQWLSVVFIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(63425..64360)
                     /gene="hprK"
                     /locus_tag="ACL8C7_000607"
     CDS             complement(63425..64360)
                     /gene="hprK"
                     /locus_tag="ACL8C7_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HGS1394862.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(64490..64666)
                     /gene="rpsU"
                     /locus_tag="ACL8C7_000608"
     CDS             complement(64490..64666)
                     /gene="rpsU"
                     /locus_tag="ACL8C7_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HGS1394863.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(64806..65513)
                     /locus_tag="ACL8C7_000609"
     CDS             complement(64806..65513)
                     /locus_tag="ACL8C7_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HGS1394864.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            65664..66692
                     /gene="queA"
                     /locus_tag="ACL8C7_000610"
     CDS             65664..66692
                     /gene="queA"
                     /locus_tag="ACL8C7_000610"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HGS1394865.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKIVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            complement(67343..67732)
                     /locus_tag="ACL8C7_000611"
     CDS             complement(67343..67732)
                     /locus_tag="ACL8C7_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HGS1394866.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(67836..68492)
                     /locus_tag="ACL8C7_000612"
     CDS             complement(67836..68492)
                     /locus_tag="ACL8C7_000612"
                     /inference="COORDINATES: protein motif:HMM:NF019142.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HGS1394867.1"
                     /translation="MFRRNLNTSFAHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVK
                     VATKPKVVTKKISSTRIRFEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGYVTE
                     QVTVDRKEATDTVIKVPAKSKIEEVLVPFATKYEADNDLSAGQEQEITLGKNGKTVTT
                     ITYNVDGKSGQVTESTLSQKKTLKQELLKKEPSPKFLSKKFQSKQNISMAQLLIKVKK
                     "
     gene            complement(69193..69744)
                     /locus_tag="ACL8C7_000613"
     CDS             complement(69193..69744)
                     /locus_tag="ACL8C7_000613"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1394868.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSTENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(70094..70918)
                     /gene="nadE"
                     /locus_tag="ACL8C7_000614"
     CDS             complement(70094..70918)
                     /gene="nadE"
                     /locus_tag="ACL8C7_000614"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HGS1394869.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(70915..72375)
                     /locus_tag="ACL8C7_000615"
     CDS             complement(70915..72375)
                     /locus_tag="ACL8C7_000615"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HGS1394870.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIYNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFPEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DENGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(72491..72979)
                     /locus_tag="ACL8C7_000616"
     CDS             complement(72491..72979)
                     /locus_tag="ACL8C7_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6773 family protein"
                     /protein_id="HGS1394871.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(72969..73178)
                     /locus_tag="ACL8C7_000617"
     CDS             complement(72969..73178)
                     /locus_tag="ACL8C7_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS1394872.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(73564..74292)
                     /locus_tag="ACL8C7_000618"
     CDS             complement(73564..74292)
                     /locus_tag="ACL8C7_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1394873.1"
                     /translation="MKLNKLNFLKENIRNLYSSGVIYLSLLISFIPPILLTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVASNTMSISQ
                     YLVVITTIILLYFFTLKKSKKYSF"
     gene            complement(74308..75178)
                     /locus_tag="ACL8C7_000619"
                     /pseudo
     CDS             complement(74308..75178)
                     /locus_tag="ACL8C7_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220488.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(75534..>75824)
                     /locus_tag="ACL8C7_000620"
     CDS             complement(75534..>75824)
                     /locus_tag="ACL8C7_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HGS1394874.1"
                     /translation="VVSYDDAAQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHD
                     AKGNKIDRAPNPMELLTIKVPQPVQSGDMVRALKEGLINLYKEDGTSVTVRA"
BASE COUNT        22704 a        16719 c        13797 g        22604 t
ORIGIN      
        1 agagtttttt aaaagtgttt tgatggtttg gatttcttct ttaattgatt tcatattact
       61 attatataat gctttttgat tttagtctgg tataaatatt gctttcctcc aaaatggtca
      121 tagttttact ggcaaatcta acatatcacg gataaattaa caagtgattt ctgaattgct
      181 aaacattttc ttttcttata gcataccata ctttaagatt ttgtctttaa gaaagatatt
      241 tccaagaaaa acgttcgttt ttttatctat tttcaaaaaa accaaaaact gaattgaaag
      301 aatttttaga aaatttctgt tttttcttta cagtgaaaaa aaattctgct ataatgtctt
      361 atgtaataaa atatgacaat aaaaggagaa cgatatgaca tctgctaaag aatatatcca
      421 aagcgtgttt gaaactgtga aagctcgtaa cgggcacgag gctgaattcc tccaagctgt
      481 tgaagaattt ttcaacactt tagaacctgt atttgaaaaa caccctgagt atatcgaaga
      541 aaatatcttg gcacgtatta ctgagcctga gcgcgtggtt tctttccgtg ttccttgggt
      601 tgaccgtgat ggaaaaattc aagtaaaccg tggttaccgt gttcaattca actcagctgt
      661 tggaccatac aaaggtggac ttcgtttcca cccaactgta aaccaaggga tcttgaaatt
      721 cctcggattt gaacaaatct ttaaaaatgt cttgactgga cttcctatcg gtggaggtaa
      781 aggtggatca gacttcgatc ctaaaggtaa aacagatgct gaagtgatgc gcttctgcca
      841 aagcttcatg actgaattgc aaaaacacat tggaccatca cttgacgtac ctgctggtga
      901 tatcggtgtt ggtggacgtg agattggtta cctttacggt caatacaagc gtcttaacca
      961 atttgatgct ggtgtcttga ctggtaaacc tcttggattt ggtggtagct tgattcgtcc
     1021 agaagcaact ggttacggtt tggtttacta tactgaagaa atgctcaaag ctaacggtaa
     1081 cagctttgct ggtaagaaag tggttatttc aggttctggt aacgttgctc aatacgctct
     1141 tcaaaaagca accgaacttg gtgcaacagt tatctctgtt tctgactcaa acggctatgt
     1201 tatcgatgaa aacggtatcg acttcgatct tttggttgat gttaaagaaa aacgtcgcgc
     1261 tcgtttgact gagtatgcag ctgagaaagc aactgctact tatcatgaag gttctgtatg
     1321 gacttacgct ggaaactatg acattgcgct tccatgtgct actcaaaacg aaatcaacgg
     1381 tgaagcagct aaacgtttgg ttgctcaagg cgttatctgt gtatctgaag gtgccaacat
     1441 gccaagcaac cttgatgcca tcaaagttta caaagaaaat ggtatcttct acggacctgc
     1501 caaagctgcc aacgctggtg gtgtagccgt ttcagccctt gaaatgagcc aaaacagcct
     1561 tcgcctctca tggactcgtg aagaagttga tggacgtctc aaagacatca tgaccaacat
     1621 ctttaacaca gctaaaacaa cttcagaaac atatggtctt gataaagact accttgcagg
     1681 agctaacatt gctgcctttg aaaatgtagc aaacgctatg attgcccaag gcgtggtata
     1741 aaaaaaaatt acggaaactg actacccaga cgggtagcca gttttttcaa ttcctaaaat
     1801 ttaagattct aatacccttt atgcaaaaat atagaattct acctttttct ttatataggc
     1861 taatgttttt aatatattta ttgtctattt ttgaaaagac aataaaacta ttctactata
     1921 gattatcatt tcccacaatt cataactcaa acctaatatt ttgttataaa acagtagatt
     1981 ttatttatta tatctggcac cttaaaaagt aagaaatata aattaaaatt taaaactctt
     2041 tttccaattc tctttcaata gcttttcgct tgcaatcaat tagtttattc aagtacagta
     2101 gcaagttaat gtagtctata cccgtttcaa atatcttttt aattctttct aggagttctt
     2161 tttctaattc caacaccgga acatgactac cagtataaaa atgtgaatag ggagtaaaat
     2221 gtatttcttg gaatgacttc ttaccaaatc ctttagctct gagaagatta aatagtatta
     2281 gtttttgatt gttgttttct aaaaattcta cacctagatt gaccaatcta attgcagatt
     2341 gctcattatt tgtttcctcc agtatttcta atatgatctg actgtcattt tttataatat
     2401 catcaatcat attattgtag tagtaatatg gcctatttat tgcaaaacgg ataaactttt
     2461 tataaatttc tttcttatct ctaaattcac ttatagaatg taataccatg tatcctaaat
     2521 tggaatgacc tattctcaat tcatcaattt tcttcaatac ttctaccgaa aaatcaacat
     2581 ctttttcacc taatttttga aaaagattat agctgtgatt ctgacaattt tctaaattta
     2641 ttaaatacca aaacttcaac tcttttactc caattagatt tattaatttt ggcacctctt
     2701 cttctcttat aaaatcagaa ataacaaaat ttgtattccc agctttttgt attaacaact
     2761 cttttaaact aggatctttc aaaatcaatc tctcaaaatt taaaattgta aaataacatg
     2821 gtaaagaatt agcttctaga atactcttta atgtttgtag atcttcattt ttaacgtttt
     2881 caagttgtgt taaataagca agttgccatt catatttttc tgattctgga gaggaaacaa
     2941 taacagactg cattgaactt tcctcaatat tttctaaaaa actaatcgga ttcatattta
     3001 caaaatgata gtttgattta aacatataat ttagaaattt aatcttttta tcattttttg
     3061 atagtaaaaa catattgaat agtactagct caatgttatt gtcattcata aataagctat
     3121 gtttgaattg atttgcaaaa ttaaaaattt taagccaaac atttgaatag ctatttgcaa
     3181 tttgttgtag tttaatttca gaagcatcat aaaaccaagc atggttagga tttgttaaat
     3241 tattatatat tttttgtctg tcagaaatta tataatcatc aaaaacaatc ggtaaatttt
     3301 ctttcacttc ggctttatgc aaagcataaa ctattttttc tccaatcata gataagtttt
     3361 taatgtcatt aaaaaataat ttcctaatat ttctcaaatc tccaaagata gtattacgat
     3421 gactttctga ataggtcaaa atttttcttc tgtaatcata tagcattttc tcaatataaa
     3481 atctagtttc acaactccct atattataca aattcgctaa aagttttagt atacttctat
     3541 gatactgttt taatttttca ctatccggga ctttatagcg cccaaaagta aatttctctt
     3601 catgagcctc tgttctttcg atttcaattt taagaaactg cttcaaaatt gtcacgatta
     3661 attcttggtt ataacttttc gtcaaatcaa gattagcaag ttcagaaatg gtattttcag
     3721 ctaaggtata atcaatatat tctctttctg taaccaaccc gtagtttgct tcaagaatac
     3781 tataaacctc agaaatttta ttaggatttt tatcaaagta ctttaacaat aattggagaa
     3841 tttgactaca atattttgtc cgtgtagtta caaatacaat atttaaaact gaatcctcaa
     3901 tagatccctt tttatccttc tgattaataa aattagtctt tgtataaacc tgagactcta
     3961 tattatcaat tttattttta acgtgtgaaa ttgcttctaa aggaagtaat actccaaatt
     4021 gtattaaaaa cttttcttta agttcatcac tttcaaaatt actttcattg taataatatg
     4081 atttaactgc atcagaaacg ccttctaaat cactctcttt cctaataaaa ttggaacatt
     4141 gatttagtat ttgaacaact ctttggtcgt ttactggata taactcatgt aaaatttcta
     4201 aaattgatat tttcttgtta attaaaaact tgataactat ataatcatct aatgattgat
     4261 ctgctatctt tacaattttg tcgttataaa tattacacaa ctctctttca tgaagcttct
     4321 ccactgcact cttaaagtca gtatttgtta tgtcagttat ttttagtaat ttattgaatt
     4381 cctggttctc ttctaaactt tccagtctaa tcttttttaa gtaagataaa ataaatagag
     4441 tcttttgttc tgcataaata atgttgtttt tatttaaaat ttcttcatag taatctttta
     4501 aaatatcaat ctcatcatta aaattagtca aatcctgaga gctagataac tttgctgcaa
     4561 tgactgcaat acgcggattg cttttagata tcgtttttat atgttcaatt tcttgattgg
     4621 taaaatcgtt tcgagaaaat tgattgagta attccttaaa attatcatct tttataagtt
     4681 ctggctcaat attattgtac ccataaactt taatattatt gattacatct tttttagcat
     4741 aatcacgtac cgtaagaata aaccgaatat tactagtcgt gttcagtagc ccaagtgtag
     4801 aaatataatt ttgtgtagta ttaacatcat caataaaaat aatattttct ttgtgtaaat
     4861 ttagattgcg ttttacatct tggtaaatat cctgattatt gctcttgaca caaataatgt
     4921 tatatttatt tcgatccagc aaagagcaaa tttcaattgc taatctagtt ttccctgttc
     4981 caggcttagc agatattaag aagattcgtt tttcacttga tttaatggta tttataattt
     5041 cacttacatc tccaatatag tcatttgata taggagcatt agttttactc tcatcatgaa
     5101 ttcttatgaa gtcattgata gaccaaactt gctctgtaga ttcactgatt gatagatact
     5161 cttttgctaa atattgaaaa tctatctttg taagatcatt agcaatttca ttaattccaa
     5221 tcaattctag atgataaggc tcagccattt tttctagatc ttctttttgt ttaattgtta
     5281 tatttgaaga agtatgacaa caaataagtc tcccaacttt atcttcagca atattttcct
     5341 ctaaaatttt tttcttaact gactgaatgt ctccttctaa tttagatatt acagacttat
     5401 gggtgccata cataatataa acatatttac cattttcgac agcgtaagaa tctgggatcc
     5461 ctttagttgt tttatctgtt ccttcctgtg agcctaatga aacaatatta aaattgtatt
     5521 ttctacttag gtacgcgtca cctagttttt gaaacttccc tccctctagc tctttaatat
     5581 gttgctcaat tttatttctt aaactcatta taaaaacctt tccagataag tatttcaaca
     5641 taattatatc acactagtca aaaccataag gtatagttta attaacaaac tcttgtacta
     5701 cgttaattta gagtagtaaa ccaattatac aaaaattatt tatttcctaa acaactatat
     5761 aaaaagtttg ccccttttta aacaaaaaag aaaaaccgct actcctaaga atagcggttt
     5821 aatcatgttt ttaagctact aatgtagttg ctctattatt taagagtaac tgaagctcca
     5881 gcttcttcca atttagcttt gatttcttca gcttctgcag ttgcaacgcc ttctttaaca
     5941 agtgctggtg caccgtcaac aagttcttta gcttctttaa gaccaagacc agtgatttca
     6001 cgtacaactt tgataacacc aacttttttg tcgcctgcag atgtcaattc aacgtcgaat
     6061 gaatctttag cagcaccagc atcagctgca tcagctgcag caacagctac aggagcagct
     6121 gcagttacac caaattcttc ttcgatagct tttacaaggt cgttcaattc aaggattgaa
     6181 gcttctttaa tttcagcaat aatgttttca atgttcaatg ccattgttat ttcctccaaa
     6241 taagttttaa attttataat agtttttttc gtagctaggc tacgctatgt agcttaagat
     6301 taagccgcgt cttctttgct ttctgcaacc gctttgactg caagagcaac gttgcgcact
     6361 ggcgcttgaa gtacagaaag gagcatagaa agaagtcctt cgcggtttgg aagagttgca
     6421 agtgcaagaa tctcttcttt agatgcgaca gcgccttcga ttgcaccacc tttaatttca
     6481 agtgcttcag cgtttttaga aaagtcgttc aagattttcg ctggtgcgat aacatcttca
     6541 ttagaaaatg ctactgcaga tggtccaaca aatacagatg caagatcttc aagaccagct
     6601 ttttcagctg cacgacgcaa gattgagttt ttaataactt tatactcaac ttcgcttcca
     6661 cgaagctcac gacgaagaac tgtatcttgc tcaactgtca aaccacgagc gtctacaacg
     6721 acgatagatg cagcagcttt cattttttca gctactacgt caactagttc cgctttttta
     6781 gcaataattg cttcactcat tagtgtgttc acctccgtaa ttattttgct tggggaattt
     6841 ttcaaaaaga aaaacgcgcc caaacctaga cacgaaagta caatacgctt ctttttacat
     6901 gatacgtctt gtcctcggta ggatatttat gagtcgagct cccctactgt cttaggcagt
     6961 ttttttaaac cgtatataag tatagcatag tcaaaaaaag aatgcaagat ttttgcaaac
     7021 tttttttaaa atttttcgtg atttttcttt taaagttcta ctgtcaggac ttgaccttgc
     7081 ttaacaacct gttctccggc gatataaaca tcatctacat cactagattt aactgcataa
     7141 accaggtgag acagcatatt ttcctgaggt tggagatgaa ttttcccttg tggttgaatg
     7201 accagaaaat ctgcttgctt gccgacttcc agacttccta tctgattttc cattccaagg
     7261 gccttagccc cttcgattgt cagtaccttg agagctgttt cgattggaaa ctggctggca
     7321 tccccacttt tcatcttctg aagaagagct gcagtccttc cttcctcaaa catatctaga
     7381 ttgttattgg aagcaaccga gtcagtcgca attccgactg ctactcccgc tttttggagc
     7441 tggataattg gagcaattcc tgatgccagt ttgaggttac tgataggatt gtgggcgata
     7501 gccacttgag aagatgccaa gcgttcaatt tctctctcgt ttaattcgac cccgtgagca
     7561 aatacggacg gatgatctaa ataacccagt tcttcaagaa aagcaagggg gcgtttgccg
     7621 tatcgtttga ggataattcc tgactcctcc ttggtctccg ccacatggac atggagcgga
     7681 atatttagct cttttgccat ttccaaactc gcttccagca agtctctact gcagctatac
     7741 ggagaatgag gtgctaccat aaccttgaaa tttggatttt tatattttaa gatttcgtct
     7801 atgatggatc gagttctgct tatagtctca gcagttgttt ctgtctctga agaaaagaga
     7861 gtcggagaaa aataacaacg catcttggaa gttttcacca cctgataaat ttgctgaata
     7921 tccacaccat tgggattata catatcgtta aaggttgttg ttcctgactg gagcatctct
     7981 gtcagggctt ctttgaccgc attggtagtc atgtcgggag taaactcaga ttctgctggc
     8041 cagatatagt cattgagcca ttcatggaga ttgctgtcat ctcggatccc tctcagacct
     8101 gtcattgcag aatgggtgtg acaattgacc aaaccaggca taatccaagc tccctgatag
     8161 tctataatct gctcagcttg ctctaaaaac gctggcttat cttgaccgac atagacgatt
     8221 tgagaatcct tgactgctaa gattccatca agataaacat ggaaatcttg atcacaagtc
     8281 acgatattta catgctgaaa gactttcatt ataggctcct tttctaaaag acaagttgta
     8341 ctctcttcaa accacttcag attcactttg ccgtaggttg ctctttgatt ttcattgagt
     8401 attacagtaa acaatttttc tagctattgt aacaaaaaag tcactcgaag gcaacttttt
     8461 tcgtccataa actttcaaaa gagaatggct tattcagaac taaaagccgc agctttttgc
     8521 atttggtaat acttaccctt tctatccatg agttcttgat ggttaccata ttcaacaata
     8581 tcaccatcta ctaagacaag aattaaatcc gcatcctgaa tggttgacaa acagtgagca
     8641 atgatgaagc ttgtgcggcc cttcatgagt tttgcaaagg catcctgtac cagcacttct
     8701 gtccgtgtat caatggaaga agttgcctcg tctaagataa gaatctttgg aatagccaga
     8761 aagactcggg ctatggtcaa gagctgagct tggccgacag agagagattc tccagcattt
     8821 tccaacttgg tatcgtatcc ctgtggcaac tgttggatga aaaagtctgc attagctgct
     8881 ttggcagcag caattacttg ctctcgactg gcttcaggat tgccaaaggc aatattatca
     8941 tgaatggtcc cttgtgtgag ccaggtttct tgaagcacca taccaaactg ctgtctcaat
     9001 gatactcgtg tataatcata aatggattgc ccatccagca agatatctcc cgagctaatg
     9061 ggataaaaac gcataaggag attgataaga gttgattttc cagcacctgt aggaccaacg
     9121 atggctacct tactaccagc tggaatatcg atagacaact ccttaatcaa aattttttca
     9181 ggatggtagc caaaagagac atgtttaaag gaaatagctc ccttaacttg gtcactggtc
     9241 aagacttcct tacctgtttc agccacttca gggctatcta agactccata gatacgctct
     9301 acgcaagcca gagcactttg caactcagct agcactgaag aaatatcgtt aaagggcttg
     9361 gtgtattgct gaacatagtt caaaaaagtc actaaacgac cgacggtcaa ggttgaaccc
     9421 atcatgatac gataagctcc tactccagct aaaagggcat aaatgagtgc atttacaaag
     9481 cgagtcgaag gattgaccgt tgaagaataa aagatggctg actgagaata gcctgagtag
     9541 ttgtcataag cctcacgcaa tctttggata aattctgttt gagcattgaa ggactggatt
     9601 atagtctgct ggctaagcga ttcttcaatc aactgagtct gaattcccct cgtctctgtt
     9661 tgcttctgga agagatgata ggatctcttg gcaataaagc gtgaaatcac catggacagt
     9721 ggcgtcaaca gcaagactaa gagagtcatg aggagatgaa tttggagcat ggctagaata
     9781 ctaaccaaaa tcatcaaaac accaatgaaa aattggttaa aaatcatggt caagccagct
     9841 gccaactgtt cgatgtccgt ggttacacga ctaaccatct ctccactacc ttgcctatct
     9901 acaaaggcaa tcggtaaacg atggagctta tggatgattc gctcccgtaa atctctggta
     9961 taagagaaga ttagacgatt atagaggaga ggattggccc attgtaccag agtatttcct
    10021 attaccacca agagcatctg gagaaaaatc tgccaaaaaa ctggtgatga accagccact
    10081 aggacttggt caatgacctg cccaatcaga ataggtaggt aaattgataa gccaacttgg
    10141 gcaatagttc ctagaaaggc taggaaaagg aagaaaggat ggcttgctaa atctacggct
    10201 aaacgtttga gcgtctggtt tacagtttgt cgtttcattc tagtcctcct ttccatgttg
    10261 ggatgcattg atttcacgat agacttggct ggatttcatc aagtcatcgt gcttgccaac
    10321 agctagcaac tcaccttttt ccaagaggag aatctggtcc gccatctgta aagttgaggt
    10381 tcgttgagag atcaaaatta agctcgtgtt tggaaaattt tctctaatag ctttcaagag
    10441 cttggactct gtaatggtat ccagtgccga ggttgcatca tctaggatga gaaacggagc
    10501 ttggcgcaag actgctcggg cgatagacaa cctttgtttt tgtccacctg agaaatttcg
    10561 cccccctgcc tcaactaggg catccaaaag tccttccttt tcactgacaa aatccttagc
    10621 ttgcgcaatc tccaaggcct gccagagttc ctggtcagat acttcttgat tgaaacctag
    10681 agtcaagttg gaacgaatgg ttcctttaaa gagttcgacc ttttgaggta cataggcaat
    10741 ccaagaccgc cactgctcca aattaagagg actacgtcca ttttgataaa ggtcaatgtt
    10801 ccccttgtct actggataaa gtccaagtaa gagttgcacc aagtttgatt taccagaacc
    10861 ggttcccccg atgataccta gaatttgtcc ttgagtcata tcaaaggaaa tgtatctcag
    10921 agaaggctgg gccgcatcag gataggtaaa ggtcaattct tggacttgta aaaccttatc
    10981 tctggtagct tgcttttgtt ctaactctga atggatatcc tctggagcct caacaaagac
    11041 ttcctcgatt cgcttggctg agatatagga ctggttgagg gaattgatca acatggctag
    11101 cttgaccaat tccaccaaaa tctgtaagag gtaattgata agagcaatga gagcaccttg
    11161 actgagcact cctccttgaa ttgaaatata gccttgccag ataataacga gaagagttcc
    11221 attgacaatc agataggtca gaggtgttaa taaactagac cagaaacctg tcttttcttg
    11281 taatctagca taaacttggt taagggtttg aaaaatctgt aactctcctt tttcttgacc
    11341 aaaagcacga ataacccgca tcccttgcaa ttgctggcgc gtttcctgaa ccagttggtc
    11401 cgttttcttt ctgagactac tgtagagagg attgaccaat cgagataacc ctacaatgac
    11461 aatggtcaaa atggcaacca tgactaagaa ccagaaagtc aactcagctg agattcgata
    11521 agccataaaa atggcaccaa aaacgataat gggcgctcgc aaaaagagac gcaggaattg
    11581 attgatacca gtctgaatct ggtaggtatc cgaagtcaag cgagtgacca aactagatgt
    11641 tgtcagacgg tctctgctgt ccttgggcaa ggaaagaata tgacgataaa gatcgtttgt
    11701 caattcctta gcaaaaccta ctgctgcctt tgctgagtaa aattgagcta tcaaggccac
    11761 taaaacgcca attactgcaa agataaggag caggccaatc tgcatccaga gatgaccttg
    11821 atctccctga ggtaaagatt ggtcaacaat cccagcaatc accatgggaa ccaagagctc
    11881 aaaaacagct tctaacagct tgaacaaggg ggctaaaatt gattccttga tgtagggttt
    11941 gaagtaagat aataggtgtt tcataaatcc cttctattca tattctagaa atgaagaaag
    12001 tgggaagccc cactctctgt tttatttgtt taagtaaggc aatagatagc catatcctgc
    12061 tttttccatc tcatccttgg ccacaaagcg taaagaagca gaattgatac agtaacggag
    12121 gccgcctaac tcccgcggtc catctgtgaa aacatgaccc aagtgagcac tgcctgaacg
    12181 agaacgaact tcaattcgct ccattccatg gctcagatcc ttgtaataat gaatcaactc
    12241 tttggaaatc ggacggctaa aacttggcca accacaacct gaagcaaact tatccttggc
    12301 aaaaaagagt ggctcacctg tcgtaatatc tacataaatc ccctcttcaa aggtttggtc
    12361 ataggcattg gtaaacggag cctctgtagc agcttcttgt gtgacacgat aagactcttc
    12421 agatagactg gtcttcaaca cctcttgact aggcttttca tagtttgctg catcaatcaa
    12481 tggcttatca gcatcggtta catcgatatg acagtaacct gaaggattct tcctgagata
    12541 atcttggtgg tagtcttcag ccagaatgta gtggcgtaat tgctccactt ctactgcaat
    12601 ctttcgaccc agcatgcgtt cctgctcctg caccactgtg tagatagctg gcaaatctgc
    12661 ttcatcctga taataaatcc cagttcgata ttggcgacca cggtcattcc cttgttgatt
    12721 gatagataga ggatcgataa ctcggaaata ataaagtaaa atctctctga gtgacacttc
    12781 cttctcatcg taaatcactt ggaccgtttc tgcatggtct gtttccttga tcaactggta
    12841 attggtcgtt tcgacttgac cattagcgta gccaacactg gtttctagca ctccagaaat
    12901 gcgtgaaaaa tattcctcta ggccccaaaa acaaccacct gctagataaa tttctgccat
    12961 ctttatttct cctttatcac gtttttaact aatactcttc gaaaatctct tcaaaccacg
    13021 tcagcgtcac cttaccgtag gtatgttact gacttcgtca gttctatctg caacctcaaa
    13081 acactgtttt gagcagcctg cggctagctt cctagtttgc tctttgattt tcattgagta
    13141 taaacttctt ttcacaaaaa ggatatgaaa ccctctggtc aagagtttcc ccatcctatc
    13201 ttctattctt tattttgctt ctacacggac accttgggta tcaactctca agtcatgcag
    13261 ttttcctttg aaaggttgct tttccaattc tgccttaatt gttggcatct tgtcatgaga
    13321 agccagaacc ataactgtcg gcccagcacc agaaaggtag gttgcatagg ccccattttc
    13381 tttggtcact tgcttaatca tcgcaaattc tcttaccaag tcctgacgat agcgctcatg
    13441 gaagaggtct ccctcgattg cttgcccagc ggtcaccatg tctcctgcca acaaggcagc
    13501 aaccgctaca ttggcgatag aacttgcagc aacagcttcc ttataagaca attttttagg
    13561 caagacacta cggctgtcgc gagtacgtaa ttcatagttt ggaatgtaag ctagaaaatc
    13621 acactctgga aagtctgcta cgatagcaga gacttgccct tcaacagaac ttgcaataac
    13681 gagattacca taaatggctg gagccacatt gtcaggatgc ccttcaatct tggtcgctaa
    13741 ctgcaatttt tcatggtctg ataagttgag ttgacccagt tggttggcta gttcaatccc
    13801 agcaacgata accgagctgg aagaacccaa accgcgcgcc aaagggacat cactggtcat
    13861 tttcaagcgt cttggttgca agtctggtac aatttgcaaa gcgattttga gcaagagatt
    13921 acgctcatca tgtggaatcc atttgccaat ctggtgttca atcagccact catctcgttc
    13981 ttcgcaaacc tcaatttgaa gatacttggt tacagctaca ccgaccgagt caaaacctgg
    14041 cccgatattg gcactggttg caggtacaat aatcttcatc ttattctcct agcaccttga
    14101 aggtattcaa gaggtcgaat tctgaaacct tcttcaattc agctgagaca ttttcaagct
    14161 gggctttatt aatcttgtgt gtgatgataa cgacacgcgc cttgtcaccc tctttgccat
    14221 cttgaaggat ttgcttaaag gaaatatctt gagcattgaa gatttcagcc aacttcaaga
    14281 cctgaccttt tgagtctaga gccaagattg agaaatagta gtttgctttg acatcttcag
    14341 gatttgccaa gaccaagtca cggctatatt cgttgaagtc tttgccaata gtaccatcat
    14401 tcaaacgacg aacgatacgg acaatatcag ctacaacact tgttgcagtt ggtttttgac
    14461 ccgcacctgg tccgtagtac atagactcac caataccgat agattctaca aagacagcgt
    14521 tcattacgcc attcacacta gcaagtgggt gcgctttagg taggaaggtt ggagtcactt
    14581 ctgcagcaat acctgaagaa gtttcctcaa tagaaccaac caatttcact acgtaaccaa
    14641 gctcttgagc tacagctacg tcttctggtg tgatattgcg gattcccttg tgggctacat
    14701 catcaaaggc aatcttcatg ccaaaggcaa attggctcaa aataaccatc ttgtaggctg
    14761 catcaatccc atctacgtca ttcgtcggat cgctttctgc aaatcctaga cgttgtgctt
    14821 ccgcaagagc atcatcgtaa gaccagcctt cttccaccat cttggtcacc atgaagttgg
    14881 aagttccgtt gactactcca agcacgcgcg taattttatc agaagccaag gaatttgcta
    14941 aagtacgaag aattggaatc ccaccagcaa ctgctgcttc gtagtaaagt gctaccttgt
    15001 tagcttgagc gatttctagc aattctgcgc catggacagc taaaaggtcc ttgttagcag
    15061 taacaacgtg ttttccagct tccaaggcac gagtgataaa ggttttagca ggctcaatac
    15121 gccccatcaa ttccactacg atagtaatat cctggtctga taaaatatca tccacattgg
    15181 ttacaaagtt aaagtcattc cctgctgcaa gcaagcgatt tttttcatct tcatccttga
    15241 ccaatacctt agcaactttg atatctgaat gtgctgattg attgattttt cctccatttt
    15301 cctttaggag gaaaggcaca ccacttgcaa cggtaccaaa tcctagtaaa gcaattttaa
    15361 ctgtcatctt tatctcctcg aaattttcta atatagccat tataacagaa ttttgtgaaa
    15421 attcctatta tagtaaatca ctatttcagt ataaaaagaa aaaacgaatc agacgattcg
    15481 ctcttcttaa aatctgaaaa tagctttcca gaaaagatta gccgattttt tgcagattga
    15541 gcactgcatc gtgactcatc aagacttgac catactcttg taagactgag cgactgatat
    15601 cactatcctc tgcaaactcg cgcatacggg ccaacagcca agctggatat gggcttggat
    15661 gattttcaat atccactaaa atggtcaaat aatagcgctc gttcattttg tagagttcag
    15721 aagtttccat ttcaaaagtc actgtcttgg caaaagctac caagtcagcc aacttagcaa
    15781 aagaaaggat gtagtagatg taaggttctt tcttactctc agcttcttgt tcagcctgct
    15841 cttgctcttc ttccttggct tcaacttgct caagagattg aatggcttcg atatcatcct
    15901 tggttttgtc tgcgatgctt ttttccaggg ttttgataaa ttcatctgga gacatttgag
    15961 ccaattcttc catatctggc aaatccgata agtcttcaaa atctagattt tggtcaatct
    16021 ttgacttggt cacaaagaca tctaccttat caggttttgg agtcacacgg aagctcaaca
    16081 tgcctgtatc cagaaagcta tcaggcatct ctagctcatc caagatagca taaaagaact
    16141 cttctgtttt ttcttgagga acgagaaagt cagcaatctc cattccacga tccatcaaat
    16201 cctctaaaga catcgtgatt tttaaagttg tatcactaat ttgtttcatt ttcattgcta
    16261 gtaacctcat actttcagtt ctatctatta tactagattt ttacgatttt atcaaaagaa
    16321 ggctcctcta tgcggataga ttttcccaag ggtctttcta taggagactc caaaagaaaa
    16381 tttctgcaga cagatagaaa aagccttcaa aatcggctct tagccgactt tgaagacctt
    16441 atacatcaga atacttataa tttaaaggtt gctacaccga ggatagaacg atttaagttt
    16501 ctgagaattt gaagactttg ctcaaatttc ttataacgag tcactccgta ctcttcaaca
    16561 agaaggactg tatctctttc caaaagagat gatacatcct gtaaatctac aaaatgcatt
    16621 ccttttaaag cttcttgact ctgtttcaat ttatctagga tagctttatt tgagctaacg
    16681 atggtcaatt cctgtccagt atttttgtat gacaaaacat ctgctaggtt agcaattgtt
    16741 gtaatctctg ttacaaaatc aatttgatac tgagaaaaat cacctactct attgattgtt
    16801 ggattaaaga gataaactaa cacatttccc atcacaacca aaatcacaca aaccactcca
    16861 ataacaacta aacgaagaat cagatttttc acatttaagc caagcgctgt ttcaccattt
    16921 gcgttcaatt ctttagagtt gatggtttcc agtttttcaa ttttcacatt tgcataggca
    16981 tgtttaaatt tctcaatcaa cccatcaatt tttttctcta acaagtcatt ggcatcttta
    17041 cttgatgtca aaattttcac accaacccct gcatcgtcaa tcatatagta gacggtcaat
    17101 tttttccacc aatagtcatt cgttgaattt ttcaaggttg tttctgtcgt gtctaattca
    17161 ctggcaattt ttttcaactc actgggttct acatcattga aaagataagc tccattcaaa
    17221 ttaccatcaa tcaatttccc ataaaaatca ctataaccac caatttgatg attcaaaatc
    17281 gttttggccg aatcttctgg aggagtgatt ttatagataa gataagttga ataacttgtt
    17341 gtatctttga cagtgttttt attcctaact gctttaattg taaatggtac agcaatgaga
    17401 gcaaataaag cgatgagagc taaaatattt gcttttcgct ttttataaag atttgcaaac
    17461 aaatcagcta ctgaataatg ttcaaacatg atttttttct cctttgttta gtagatacta
    17521 gttttccttt gtaagcattt ttgctacaaa tataatcaca agaacaattc cccagaattg
    17581 cattgtaaat aaattgaaga aactttctga aaagctgctt cttggcataa agaatagatt
    17641 attcaagatg agtagggata aagcaaatag gattgtcctt gagcgatagg ctacttgcag
    17701 catggctata aataatacgc cgagtaagaa actaagcaga aagactccaa tcataccata
    17761 gtcggtatac aactccatga tataactact tccgatacca tgccctttca agtattcctt
    17821 gttcaagaca agataggata gattgtgggc ataactatta ctatcaatag ctagttccac
    17881 actattggtt gtatgttcaa aggcttttcc tccgaaaatg gctcccaaac tcccccttgc
    17941 aaaataatca agaacaggac caaaagtaaa attacggaaa tctcggtaag ggaggctact
    18001 gttaaataga aaacctcgag ccagaacacc aaaactagtc ccttgtttat agataaagtc
    18061 aagtaagata tcccagaaac ctgtatggga aacttggaca ttatcccgta cataattgag
    18121 tactcccatc gctaacatga gaataggaga acctacaaaa atcgctaact tttctttaaa
    18181 cccaatccat tttccttttt cagtttgctc ccgcataaag taataaacaa aagcaaataa
    18241 aatacttaaa ataaagggat ttcgtgtccc aattgccaaa tgaatagtat tagctgcaat
    18301 aaaggagaca agcactgctg tggcctgcaa tttctttggc ttggttgcca gatacataca
    18361 cattgcatag accgtaaagg tagacaaaat gtaggtaaaa taaggcagtt tactttcaaa
    18421 atttgcatag taggcatagt aggaagtctg caaacgatac aagagccgtt caaataaccg
    18481 aatgaaatag aaaggatagg ttagaagaaa aactcctagt gatacaaagc gtaaccgctt
    18541 gatataaacc tcttttagag aatttcctat atttgctact tttattttct tcctagctat
    18601 gaagtaacga gccagaatgc ctcctgtggt caagcccaga atcgaaacca tgacaactat
    18661 aaaggcaaaa cgataggcta ttggatgata ggtatccaaa gcaccatccc taaaataatc
    18721 aatggtcggt cttgatacca gaaatacaaa aatggttaaa tagaaaataa aatggattaa
    18781 gtaatacttg atatcattcc aacaagcaat taagctacta accaacaaga acaataaagt
    18841 agaaagtaag ctaacattat tattattaaa cagatacaca attccactta ctagcgtcaa
    18901 ggcataactg actatggtca aactaaataa taatcgtttc ccatcaatca cttggtcacc
    18961 cccgttctaa tgtaattttt tagatttttc aatatttttc agtaataaga atcgatataa
    19021 ggaaatattt atgaataggg ccaaagcact aattcttctc cccttacgga aaattggatt
    19081 cctagaaata gcaaaggcat ggccttttaa aaaacgatga atctgagaat aggctttaaa
    19141 ctgtttatac tgatcatcta gcaacatctt atccagaata aagaagtggg cataggccaa
    19201 tctgaaaaaa gcgacctctt tcaagtcagg atagtttttc acaacttcat tataaaactt
    19261 ttggtagata tcaatatagg ctaaatcctt ctctgcatag ggtttggtcg taatactatc
    19321 ccctctatgg aaatagtaat aatagggttt agtattaacc acatacttct tggccaactt
    19381 gattaaatca aaatggtaat aggcatcttc gtaaatcaac cccttaggaa aggatagggc
    19441 agttgcaatc tgtctcttga ttagcttatt gcaaatcgtc ccaggtattt tttcacctat
    19501 gaggtattcc tttagaaatg tttgagaatc acagacaaaa tagtcatcct gattggctga
    19561 ctgtgggctt tcatcattag catagacatt catgacacca cagctcgaaa catccgcatc
    19621 ttcttgaact aattgctcat ataagctctg aatcatttct ggatggatat aatcatctga
    19681 gtcaataaaa atcagataat ccccgtgagc ctgcttcatc ccatcatttc gtgcttgcga
    19741 caatccttcg ttctttttat gaagcactga caccctgtca tcttgttcag cgattgaatc
    19801 acacaagcga ccactttcat ctgttgcacc atcatcaaca agaataattt ccagattttg
    19861 ataggtctgc ttctgaatgg aagctatcga tttttctagg tactgcgcca cattatagac
    19921 tggcacaatc acactaatta atgcagtttc catgctactc ctctaatagt ttttctactt
    19981 gttcgatttg ttttgtaatt gtaaattgtt gaatgaattg gctagcctca tcgacatcaa
    20041 agtttgaggc agaagtcatg taattagtaa tcgcctgagc tgcctcttga ttgctctcaa
    20101 tgatttgtcc aaatcgtcct tcttgggata attcctcagc ccctccaacg tccgtagaga
    20161 taaaagggag tcccagactc aaggcctcca catacactcc aggaaaacct tcttgtttag
    20221 acatagacaa aagaactttc gtctgagata gatactgata aggatttttt tgataaccaa
    20281 ggaaatgtac atagtcctca atcccatact ctttgactcg ttttttcagt tcctcttcca
    20341 tatcaccagc cccgataaaa tagagatgat agttttttcc ctcttggtgt aataatcgta
    20401 tcacttccac tacacggtca gaacccttat tttcctcaat ccgtccgata gtacagatac
    20461 tttgaggagc aatctcgata tcgatcttct cttgagattt ttctagaata gtctgaaaat
    20521 catatccatt gtagattgtc tgtaatttag aagtataatc tggataaact tccttgatag
    20581 aattgctggt cttttttgaa atccctacaa ttgtattcgc agcatccaac tggcttctat
    20641 gtgattctct tttagagcta tccttaagaa gttcttcaat acttccatga atccaagata
    20701 tcttcttgac ttctcttctt ttagagaaca acagtggtgg attcataatg gtaaaagaaa
    20761 cttcaacatc ataatcatct tttacaagca aacgacgagc cagtcttgga aaataaattc
    20821 tcattctcca caaaaaagct cgtaaccatc tggtttggcg ataatcttga agggatttta
    20881 aaatgcgtac atgctttgga acagattcat atcccttgtc aaagtgctcc atttcaagaa
    20941 tatcaatatc atacttttct ggatccagat ttgaaacaat ggttgataga atcttctctg
    21001 caccacctcc aagagaaaaa gaccacataa aaaataagat ttttttctta gccaccatat
    21061 tctcccttgt attctgtata agacttatcc atatcagcaa tgacagtatc atgatgcggt
    21121 acctgcttgt ctgctggtgg aggcgtcata taatccccaa aagcagttct gagatagaca
    21181 tcatagccga ttggaatagg catctctgtt ccttcaaatg gcaagaaaag attgtcttca
    21241 aaagatgtga ttgggtactt gtttctcatg tagccaggac ctgagcataa ttctgtaatg
    21301 ccatcacaat cagccaaatc atacttagtc atttctttct cagctttttt ccagatgcga
    21361 taacggagag attttggagt caaacccagt aaaatgcgac ttccccattt catgagagca
    21421 ccatgctttt ctggaatagt ttgcgcacaa aagagtgaat aaatcaaggc ccaacgaacc
    21481 tgttttttcc gctcagctgg atttttcgga taataatcca aaggcaaaac atccaaggcc
    21541 agaccatgtg gcaaatccaa atcctgctga taaggcttga tacaggtggt ttccttgtca
    21601 cgaatggtaa taaaaagatt acgatcaaca aaattcttgt gactctttga caagaaataa
    21661 cgttcatctg cataacgagg ccataattct gctaatttct cataatcttt acgaggcata
    21721 aaaaagtcta ggtcgtcgtc ccaaggaata aatcccttgt ttcgaagggc accaatagcg
    21781 cctccgccac agagataaca gagcaaatca tgttctttac aaaaggccac aaaatattca
    21841 gccatctcca gactacgagc ctgaattgct tttaaatcag tcatattgtt cattattctt
    21901 tctatcgtat cgtttcatta taccacaaac aaggggtgaa aatctattgc agactgtaaa
    21961 aaatcaaagc ctgactgcta tccaaatagc tatcaaactt tgatttttct gtcttatact
    22021 cttcgaaaat ctcttcaaac cacgtcagct tcaccttgcc gtaggtatag gtaactgact
    22081 tcgtcagtct tatctacaac ctcaaaactg tgtttttagc agcctgcggc tagcttccta
    22141 gtttgcactt taattttcat tgagtattat cttatctcaa gcccatttga gcgagcttgg
    22201 tttgatattt gttttgatca accagcaagc ccaagcctcc ataaacatca taggtatcta
    22261 cccagtcacc cagttctgga atcgtcaatt tttcaatacc attttttgct ccatccaaaa
    22321 cagataaacc gtttgttagg aggaaagtat aggggacgtt ggttgaggtc atagcaaaaa
    22381 cctttccaag agcttcagaa ccagtgaaaa gtttagtggg atctttaatt tgctctaaaa
    22441 ttgctgttaa aacttgttgc tgtctttttg tacggccgta atccgcctca tcatcatcac
    22501 ggaaacgagc ataattgagc agggtcgagc cattcatctg ctgttttccg actttaatgg
    22561 tttgggttgg agactcagtc tcggtagcgt ataaatcatc tccgactgta gcttctgtta
    22621 ggggacgccc attcaatgtt gaaaattgag catcaatcgt caccccatca gggaaaagcg
    22681 tgtcaatcgc tgtggcaaag gcctggaaat caaccaaggc gtagtactta atgtccaagt
    22741 caaaattatc tttcaagact tggcgaacca tttctgcccc tttttgcccc tcttgttctc
    22801 ctaactcgta ggctacgttt aacttgttat ctgtctgttt tctaccatta atcacttgac
    22861 tataaccatc tatatagacc aaattatcac gcatgaaact gactagcttc attttcttat
    22921 ctgagccccc gacatttaat accataatag agtcagttcg tgtctcaaca ctgttctggc
    22981 cgattcgacc atcagtaccc atgattaaaa tattaactcc atctctagtg tcctgaccat
    23041 taaagacttc tacttgagct gcccgggcat cagcagtttt ctttgcgcta gcatcttggt
    23101 aaccacgcaa aaacatgaat accatggcca aagccacaca gaccaaaagt gaaaaaatca
    23161 ccataaaaat tcgtttaaga cggagcttcc gtcttttctt ttttggaggg aaagagagtg
    23221 cttgtgattt ggattgtgag cgactccggt tcgcatagct tggtaagtca acctgctctt
    23281 ctctttcttg ttccaagcta gagctactat ttcccctagc aagagttagc ttttcttgca
    23341 aataggcaaa ctcatttttt tctctctcat tgaggtagtg aatatttttt agcaaataat
    23401 cataacgcaa ctgctcatga tgacttaagg gattttcttt actcatcttc tctcctttcc
    23461 atggtctgat attggataaa taggataggc acccagaatt ttatactgga ttccaatcgc
    23521 ttctaattct ttttgggcaa agtggaccaa gtccttatcg gtataatcca catcgataat
    23581 gaaaaagtat tcacccagtg ctgtcttgag tggacgactt tcaatttttg tcaagtcaat
    23641 tcctcgccaa gcaaaggtcg acagggcctt ataaagtgca cctggaaggt tgtcaggtaa
    23701 tgtcaaggcc aaactcatct tttcagtttg tgcttgcaag ggaatactag gcttttcagc
    23761 tcctagaacc cagaaacgtg tgaaattggc ttccatttcc tgaatatcct cggcaatcag
    23821 ttccaatcca tattcttcag cagaacttct aggtgcaact gctgcaaagg gctggtctgg
    23881 atgttcggaa ataaaacggg ccgcataagc tgtactagct gttacctcga tttgagcctc
    23941 tggatattgt tcatcgatga atttctttcc ttgagccaag gcctgtggat gtgaaaaaat
    24001 cttttcaatc ttagtatggc ctggaaccac catcaactgc tgatgaatag gctgaacgat
    24061 ttctgctact gcttggatgt gagcctgatg aaaaagatag tccaaggttt catgaacact
    24121 accctcaata gaattttcaa ctggcaccac agaatagttc actaatcctt gctcataagc
    24181 cttgatgaca tctgtaatgt tggcaaaagc ctgcaattcc tcatgaggaa aagctgtctg
    24241 cacaacgtgg tgtgaaaatg atcccttggg acctagataa gctattttca tcttagttcc
    24301 tctataattt cctctgggct tagcttggtc acatccaaaa cccgactagc cacttcctca
    24361 taccaagcct gtctttcttg gaaaatagct actagttctt ccttgctatt atttagaaaa
    24421 agcggtcgct gattgtcctt atcagctgcg atacgttggt agagggtttc aaaatctgct
    24481 ctcaggtaga tgttatctgt attagtcttg agtaagtcac gatttctctg agaaataacc
    24541 actcctcctc cagttgacac gacttggtct gtttgtagta aatcagctag gacttctgat
    24601 tctacctgac gaaaggctgt ttctcccttt tcagcgaaaa aattcgcaat ggacatacct
    24661 aggcgattct caatcagagc atccatatca aggtaattag ggtccaagcc tcttgcaata
    24721 gtcgattttc cagcccccat aaaccctaat aacaccttag ccatgaatca agctctccaa
    24781 atcatcaaag aaactaggat agctggtatt gatggcttct gcacggtcaa gatccacctc
    24841 tccatctgca accaagaggg ctgcgatagc tgtcatcatg ccgatacggt ggtcaccaaa
    24901 cgtattgact ctagcaccgt gaagagctga tttccctttg ataatcatcc catctgccgt
    24961 aggagtaata tctgctccca tactatttaa ggcgtctgcc acaacctgaa tacggtctgt
    25021 ttccttgacc ttgagctcct cagcatcctt gataactgtt acaccttggg cttgagtcgc
    25081 aagcagggca ataatgggca attcatcaat caatcgtgga atcaaagcgc caccaatttc
    25141 tgttcctttc aagtcagaag actcaacagt caaggtagaa gatttagcga ctggatcgat
    25201 ttcagtaact tctaattttc cacccatggc acgaatgaca tcaataatac cagtacgcgt
    25261 ttcgttgatt cccacattct gcagcactag atgagaattt ggattaatca aacctgcgac
    25321 taaccaaaag gctgcactgg aaatatctcc tggtacgacc accttctgtc ctgtcaattt
    25381 ttgtggccct tggactgtga ttttcttacc gtccacactt aaatgaccac caaattgttg
    25441 caacatatct tcagtatgat tacgtgtgca ctctttttcg ataataactg actccccctt
    25501 agcttgtaag gctgcaaaca tcaaggctga cttgacttgg gcagaggcaa ttggcaactc
    25561 ataatgaata ggtcttaggt ttttcgtccc ttttaagcga aggggaggca agtctcgttc
    25621 agtttgccct gagatgctga cgcccatttt tttcagtgga agggtcacac ggtccatagg
    25681 acgtttggaa agactatcat ctccaaacat ctctacttcg aaatctgcac cagcaaggac
    25741 acctgaaatc aggcgaatcg aggtgccaga atttcccata ttaagggcat tttgcggcgc
    25801 ttttaagcca gccatgccta caccttgaat ggtaataacc ccatctttat cctcaatttc
    25861 aacaccaagg tcacgaaaaa cctgcatggt cgaaagaacg tcttcacctc gcagaatatc
    25921 ataaaccttg gtctcaccct cagccaaact tccaaagata atggaacggt ggctgataga
    25981 cttgtcacct gggacgcgga tactaccatg taaatggcga atatttgttt ttagtttcat
    26041 actggacctc atacttgcaa tacttttacc tattttatca taaaaagcca gaaattcctt
    26101 aaaaattcct gactttagga tagttctttt cttatttcag caattctgaa actggttcga
    26161 aaacaatttt ttcaatgtca gaaaggtaaa tggccaattg ttgttgcttg gtaaagaatt
    26221 ctgacaagag gctatttcct tgaatctgtt taccaaagcc ttccatctta gcttggaagg
    26281 acgcatctgg catttgacct gtctgtgcta gtttttgaat ttcctcttga aaggcaagat
    26341 attctgtaaa gattttgctt gcctcagcat ctgctgcaat cgcatcttta gctgctttaa
    26401 cagccttgta ttctggtaat ccgcgtagac cgcgactgag ttcgtttgca ctatcgtaaa
    26461 tatttgacat gttcttctcc ttatttaatg acgactgtat agtcggtatt ttttgttatg
    26521 agatgctcgg ctctttccaa gtcttgagca tttttaaatg aaatttgtag gattccgtga
    26581 atatcctcac gattttcctc gttgatgtgg atgttaacca aggaagtccc acgtagcagt
    26641 tccaaaatcc gcaggatgac atcttcttca tcaggaacgt caacatagag gtcgtaagag
    26701 ctatccacac caccacgctt atggatttcc atggtctggc gttgttcacg cgcttggtta
    26761 aaaaagttcc aaatttgctc ttcatctccc ttactaatgg cctgaccaat cgattccaaa
    26821 cgttccttga aatcctcaat tctatccaga atggtctcgc tattggacaa gagaatggag
    26881 gtccacattc ctggctcgct ttccgcaatt cgggtcatat ctcgaaaacc acctgccgca
    26941 aagcgccttg ccatctcatg ctcttgagca tagaccgcag tctgctccat gagactagaa
    27001 gccaaaatat gaggaaaatg gctaatctga gaagtgacac gatcatgctc cttggcatca
    27061 atctcgataa aacgagcatg aagacctgaa agcagatcct tcatttcctt aagcgtgtcc
    27121 tgacttgtca ggcttgaagg tgtaaagata taataggcat tttcaaaaag attgacatct
    27181 gccgaagcag cccctgtctt gtgactacca gccatgggat gggccccgac aaagcgaaca
    27241 gacttgccag ccaaatactg ctccgccgca tccacaatgg ttgacttggt cgaaccagca
    27301 tctgaaataa taacgccttc tcgcaaatcc aaattggcca actccttaat gaaagcaata
    27361 gtttgtttga ttggcaagct gaggataatg acatctgcca aaggagcaaa actagcaaaa
    27421 tcatccgttg cacggtcaat catgccttct ttcaaggcga tatctctcga agcttgacta
    27481 cgattataac ctaaaatttc ataatctgga tgatcgcgtt tgataccaag tgccatagag
    27541 gctccaatca acccaagacc tgcgatatag attgtttttg ccataggaac tccttaatag
    27601 ttctttgtat agtctcggtg tttggctacc gcttctttta gttcctcaag attatctgat
    27661 gagaattttt cgaggatctc ttgcgccaga accgttgcta caactgcttc catgaccatt
    27721 cctgcagctg gaagagcagt cggatcactt ctctccacgg ttgccttgta aggttcgtgg
    27781 gtttcgatat ccacactcat aagaggttta taaagagtag gaatgggttt catgacccca
    27841 cgaacaacga tgggttgtcc attagtcata ccaccttcaa aaccacctag attattggta
    27901 cggcgagtat aaccgtcttc tttagaccag agaatttcat ccataacttg gctgccttta
    27961 cgataaccag cctcaaagcc aagaccaaat tccacccctt taaaggcatt gatagagaca
    28021 acagcttgag ccaatcttgc atccaatttt ctatcccatt ggacatagga accaagacca
    28081 actggaacgc ctccgacgac tgtctccaca accccaccga tggtatcacc atcacgtttg
    28141 atttggtcaa tatagtcctt gatttcctgt tctcgttctt ggttgacaat agaaacttca
    28201 gactgggcag ctctttgctt aatttcagcg actgtcagat tttcaggaac atcgatttcc
    28261 ttgccaccaa agaccacgac atggttggca atctccatat ccagctcagc caagaggcgt
    28321 ttggctactg caccaactgc cacccgcatg gtggtttcac gagctgatga acgctccaaa
    28381 gaatttcgca aatcatcaaa acggtactta atccccccaa ccaaatcggc atgacctggg
    28441 cgaggatgag taattttccg cttgctttta aggcggtctt caatgtcctc cgcagacatg
    28501 atgtccagcc atttctggtg gtccttattg atgacatcca tagtaatagg cgcccctgtc
    28561 gtcttcccgt ggcgaacgcc cgaagtaaag acaacctggt cactctcaat cttcatacga
    28621 ccaccacgac cgtagccacc ctgacggcgt ctaaggtcct cattgatatc ctcagctgtc
    28681 aatggaagtc cagctggaat tccctcaata atagctgtta gacgggggcc gtgtgattct
    28741 cctgcagtta aatatctcat acactctcct tattttacca agtagtcttt catctcttcc
    28801 agagaaactg ggtgaatgat cgctgaacca agctctgaca ccaagaccaa tttcaaggtg
    28861 ttaccacgcg ttttcttgtc atgagtaaga gcctgataaa gcttgtcaac ttcccaattt
    28921 tcatagtcaa caggcaagcc gaatttctga cacatctctg tgatagattg ggtaatgcca
    28981 gctggcatga ggcctttttc ctcagcaacc ttggaaatct gtaccattcc catggcaaca
    29041 gcctctccat gcatgacctt gccataaccg gcagtcgctt cgatggcatg gccaatagtg
    29101 tggccaaaat tgaggtaaag acgaatacca ttgtccaact catcttcaac caccatcttg
    29161 cgcttcacct gacaagaatg ttcaatcaag gtctctgcat gttccaaaat gctctcaaca
    29221 gaaccattca gttccgtcaa gagagcccac agttctggat cctcaatcaa gccatacttg
    29281 ataacttcac ccatcccttc aatcaactct ctttttccga gggtttcaag aacaagtgga
    29341 tcaatcagaa ccccatctgg ttgggcaaag gtccccacca tatttttagc aaatggtgtg
    29401 ttaacgcctg tctttccacc gatagaagaa tcaacctgag ctgtcaaact agtcggaatc
    29461 tgaacaaagt gaataccccg catataggta gaggctacaa atccagccag gtccccaaca
    29521 acgccaccac caagagcaac gattccatcg ctacgagtca gaccttgctt gactagaaat
    29581 tcatagactt tctgaacagt agttaaattc tttctttctt caccttctaa gaaatcaaaa
    29641 acagctacct gaaaaccagc atcttctagg ctgagcttga ccttctctgc atagagagag
    29701 gctacatggt tatctgtcac aatgactacc ttttgcggtt gccagagttc tcgcaaccac
    29761 tgaccagcct gggccataca acctttttca atctgaatat cataaggatg atgaggaata
    29821 tcgattctga ttttcatagg agagtctccc tttctttatt ggtatttttc tgttaaagac
    29881 tgccaaatct cttctgtcgg catttccttg cctgtccaca gttgaaaagc ttctgcagct
    29941 tgatagagta acattcccag accattgact gctggattgc cctgacttct agcccatttc
    30001 aaaaacggtg tttcaaaggg ttggtatatg atatctgcaa ctaagagagt ttctggtaag
    30061 actatgtttt caggaacagg agaggattgg ccatccatgc ccacactggt ggcattaact
    30121 agcaaatccg actcggcaat ccttgcttgc agttcagaaa catattctaa agcacacaaa
    30181 tccactttaa aacctgtctg ctcctgtaac ttgtctaggt aaggtcttgt tttttccata
    30241 gaaacggaac gaacaaagac cgaaatctga ctgacgccat ccaaaatagc ctgtgccaag
    30301 attgatttag ccgcaccacc tgcacccagc agggtcatct ttttacctga aattgtaaaa
    30361 gaaggcaagc acttaaaaaa tcccttgcca tctgtattat atccaattaa attgccattc
    30421 tcattgacaa ccgtattaac cgcaccaatc aagcgcgctt catcgctcag cttatccaaa
    30481 taaggaatca cctgctcctt atagggcatg gacagattga tgccaaacat ctggtagcga
    30541 cgaatattgg ccactgtttc taccaagtca ctcgcttcaa tctcccaagc cacataagca
    30601 ccgttggtag ctgtcgcctc aaaggctcta ttgtggatga agggagaaat agaatgctta
    30661 ataggattgg caacaactgc agctaaacgt gtatagccat caagcttcat ccaaaatctc
    30721 cctgattttt ttcatgctag ctagagaaat ctgcccaggg gcactaacct catccagact
    30781 ggcaaaagac caactcgaac cagtcacatc cgcagtgata cgagagacct tgcccacctt
    30841 acccatagaa atggtcacat attcctgttc aggattgagg gttttaaagc ctcgtgtata
    30901 gttcatcaag tctaagacat cctgctccgt gtgagccatc accgcaacct taacaagttt
    30961 tggatttagg atcgtcaact ctgacaagat ttccatcatg ttctcaggtg tttcttggaa
    31021 attatggtaa ctcaaaacaa gatttgggaa gtccagcatt tcctcaaaaa catccttgta
    31081 gctatagtac tcaaaatcaa tatagtctgg ttgatagaat tgcgcaactt ccttgattag
    31141 atggatatac tcttctggag aaaggtcgat ttctccacct tcggagcgag ttcgtagcgt
    31201 gaaaaccaac tcacggcctg cgaatttttc aaaaatggct ggagctacct gcaaaatcgc
    31261 ttctttaggc agatagtcgg cacgccattc aatgatgtcg gcatccaggt acctcgtggc
    31321 atccagagcc tgagcctcct ctaaacttct tggcattact gaaacgatta atttcattta
    31381 ctaaccttca tactaatcac cttgaggtaa ttactacttt catctttttt attataggca
    31441 aaatctgctg gaagaccata tttgtttaaa atctggtaac ttcttcctgc aaagccttta
    31501 tcaatttgtt ctgtaaattt ctgacgggaa acattggcag cattagtact ggcaatgata
    31561 atccctcccg gatttaaaat ctcaagactc tgggaaatca acttgtgata atccttggcc
    31621 acagagaaag tttgtttttt attccgagca aagctaggcg gatctaggac aatcacatcg
    31681 taggtcaagt ctttgcgttt ggcatatttg aaatactcaa agacatccat gactataaaa
    31741 cgatgctcgt ctgtgctgag cccatttgcc tgaaaatgcg cttgagacaa ttctcgtgaa
    31801 cgtttggcta gatcaacaga agttgtctgg ctagctcctc ccatggccgc agctactgaa
    31861 aaagccgctg tgtaggaaaa catattgagc aaggatttac ccatagccaa gccgtcaact
    31921 aaactaccgc gaacctcatg ctggtctagg aaaattcctg tcatcaagcc atcattcata
    31981 aagacttgat acaggacacc attttctaaa acagtgaaaa agtcaggtgc ttcttgacca
    32041 taaacatggg cagattcata gtccaaaccc ttaaagcgga ttttctcata agcccctaaa
    32101 acctcaggga aaacctgtct aaaggcttct gatatagtct gacgaatctg ataaacataa
    32161 gagttatacc aagaaaagac ggcgtagtcg ccataaaggt ccactgtcag acccccaaag
    32221 ccatctccct cttgattaaa gagacgaaag gcagttgtca aatcatcttg atagtaggcg
    32281 tttctctttt ctttggcttt tctaaacaac gtttcaaaga aagtttgatt gaaggccacc
    32341 ttgtctttgc tgacaaacca gcccaagccc ttgttttgct gagaaaggta ggcagtccca
    32401 agaaagtttc cttcctgacc ctgcacctct acttcctgat ccttaagatt gacattctca
    32461 agatcactgg cttctagtaa aactagcccc ttagcaagct tcttttcaac ccttttgctg
    32521 actcttattc tattcatagc taccattata tcaaactttt agacaattct caaaaaagaa
    32581 actacccttg cttttttact cttcttttaa aaaatggtat actagacttc ctgcaaaact
    32641 aggaagtaaa tgtgtaagaa tcacaataaa aaatgctctt ccgtcttgga ggagcatttc
    32701 tttttatcaa cgaaaatcaa atagcaaact atgaaactag cctcaggtta actgtgagat
    32761 tataggtaga gaggttgaat cagcaatatg tgtctgtcaa atttagtgac aaaggtagta
    32821 gaagaaagat gaagaaataa atcagcttca gtagatatct ggaaaatttg attttataga
    32881 gaagcctttt gttacaaact caatatacta tcaataaata atattataga agcaacaata
    32941 attataattt cacctatctg catcattcta tttcgaattc taaatatatg ttctatcaag
    33001 aatacttgga acacacacat tatagtaatt aacgtttttg aaattgaaaa atatccaaat
    33061 aaataaacta taaacaacaa aaatagaact atgttatatt tcttattcaa aacattcctc
    33121 cctatatttt tgattaccaa tcttaatcat ttacagctac attctaacaa actataaaag
    33181 cgtttgtcga attgaattta tcaagcaagc gaccaaccag ctcatctttt ttctatttct
    33241 gccaatatgc gtgacaggta ataatgatag ccaaaaatag caagagcaag caggaggata
    33301 agagctccta ctcccaagct gatggcaagg atagtggaga gagactgaac caagaatatg
    33361 ctcccaatta caagggccat caggattgca ctataaataa acaataaaac tatggcgact
    33421 atgccatttg aacgattcac caggtccgta atgctactcc aattggttga cagattttta
    33481 acgtccttaa agtaatggtg gcaagaaagg atgacactgg caaggatcca tgccacaata
    33541 aggtaaatca tcgaaatgat gggcaagcct agatatagag aaagaccaag caaagtcaga
    33601 actggtaaaa aggactggac agcatatata atccaaaatt tcactttcac ataacgagca
    33661 aagtcaaagg gtaaactctt aagaaaatca acattttccc tctccaagga caaggcaatt
    33721 gaatgcaggc tggtgatatt gttattgaca actgctataa acactcctac aaaaaacaag
    33781 ggtaaccagt atggaggatg aatgtctgga actatctgag aatctcggat tttggaaatc
    33841 agaccgatca tcatgagata aggaaagaaa gcacttgtaa aaagcactgt aaccacgcca
    33901 gtaccctgtc ccaagagggt gaggtggtag cgtaaaacca tgcggaaaaa tcccttttta
    33961 gtggttgaaa ttctctcctt gctgcgacgt tcttttttga acttctcctc actattaagc
    34021 aggatcacgt cataaaaacg aggaaggacc ttctttttgg tcagataaag caggaagaga
    34081 gttagtccta tccaagcgag cagacccaat atggcttctg tcgaaaaagg ctccactgct
    34141 attttgtaaa agatatgaag aggataaagg agaaatggaa tgtctctaac tttgtcaaca
    34201 atacttccaa aagtcgactg aagaaagaag ataaatatta aaggtatgag aactcctatc
    34261 ccaatcatca cattcgaaaa aatagactga tactttctga agaccctagt ttgagccaag
    34321 aaatgcactg ccactaccat cactagagcc acagagacaa ataataaggt caaggacagt
    34381 agcatcaaag gcaaacccag ccatagagaa ggagctagcc taatgtagag gaccagaaaa
    34441 taagctagga ttggtacaat tccagttaga gctggcaaaa ggacagacag tcctttagca
    34501 attataatct ctgattcttt aaaggtatag ggcctatacg atatcaaatc cttactctca
    34561 taaaagacat tgtaaaaggc cgttaaagaa gttgaaaagg caatcactag taaaatagca
    34621 atcatcgaac taaaataaat aggtatttcc tcaaaaggaa aatgaatggc tatattacta
    34681 aaacagatga tcatcaagag actggaaaaa atgtaagaac ttaagactct agcggaaaca
    34741 tttacttttt tcccaggatt cttagcctgc ttctttcgta gattagccag attagcttct
    34801 tgagatgaat aaaggatatt gatatcaact aattttttaa tgaccttgag acgcatccgc
    34861 aacctcctct tttctaccag caagactaag gtagatactt tccaaagact ggtctgggta
    34921 atcttttctc aagtcctcta cactaccaca ataaatcaaa tgcccctttt tcaaaatggc
    34981 aatccgatca cagacttgct ctgccacctc taggacatga gttgaaaaca agactgtctt
    35041 ccctttttgt gcatgttcct tcatcatctg tttcaaatca aaggcagcct ggggatccaa
    35101 accagtcaag ggttcatcca agacccaaat atcgggatca gacaagagtg ctccgatgac
    35161 aaagactttc tgacgcattc cgtgagaaag agtttcaata acctgatagc gattttcagc
    35221 aaaatcaaaa acgttcaata gcctagctag actagcctcc aagtcagatc tactcagatc
    35281 ataggatgag gcgatcaatt cccaaaattc attggccgtt aagcgtaaaa ataagtcagg
    35341 cgagtctgct acgtagccaa tctttcgttt aatagccaag cgattttccg ataactcctg
    35401 accgtctacc aaaatacgac cactgctggg tgaaatgata ctgactaggg attttatagt
    35461 ggtcgatttt ccagccccat tatgaccaat caagcccata atctctccat tttcaatctg
    35521 caaattgaga ttactcaagg cctttttatc accatacaac ttactaacat tttgaaattc
    35581 aatcatggga caactcctat ctttatctgt attatatatc gctatactag cactttgata
    35641 caaaaaaatc aatactttat tttaagtagt taaaatagtt tccttctatc ttacgcaaac
    35701 gtttgcgcta atagatactt tatgatagaa taaagaacaa gattgacaag taagaggaaa
    35761 cattatgcaa aatcaaacac tcatgcaata ctttgaatgg tatctgcccc acgacggtca
    35821 acactggacc cgtctggctg aaaatgctcc acacctagct catctgggga tcagtcacgt
    35881 ctggatgcca ccagccttca aggcaaccaa cgaaaaagat gtcggctatg gggtctatga
    35941 cttatttgac ttaggagagt tcaaccaaaa agggactgtc cgcaccaagt atggtttcaa
    36001 agaagactat cttcaagcca ttcaagccct taaagcgcag ggaattcaac ctatggccga
    36061 tgtggttctc aaccacaagg ctgctgctga tcacagggaa gcctttcaag ttattgaagt
    36121 ggatcctgta gaccgtacag ttgaacttgg agaacccttc accatcaatg gctggactag
    36181 ttttaccttc gatggtcgcc aagataccta caatgacttc cactggcact ggtaccactt
    36241 cacaggtaca gactatgatg ccaaacgccg taagtctggg atttatctga tccaagggaa
    36301 caacaagggc tgggctaacg aggaattggt cgataacgaa aacggaaact acgactacct
    36361 catgtatgcc gacctagact ttaaacatcc tgaagtcatc caaaacatct atgactgggc
    36421 tgattggttc atggaaacga ctggtgtagc tggtttccgt ttggatgccg ttaagcatat
    36481 tgactctttc tttatgcgca acttcatccg cgatatgaag gaaaaatacg gtgacgattt
    36541 ctatgttttt ggtgaatttt ggaacccaga caaggaagcc aatctggact atctcgaaaa
    36601 aacggaagaa cactttgacc ttgtcgatgt tcgtctccat cagaatctct ttgaagccag
    36661 tcaagctggc gcaaactatg accttcgtgg cattttcaca gatagcctgg ttgaactcaa
    36721 gcctgacaag gctgtgactt ttgtcgacaa ccacgatacc caacgaggac aagcccttga
    36781 gtctaccgtt gaagaatggt tcaagccagc agcctatgcc ctcattttgt tacgccaaga
    36841 cggccttcca tgtgtctttt acggagacta ctatgggatt tcaggccagt atgctcaaga
    36901 agatttcaaa gaaatccttg accgcctcct agccatccga aaagatttgg cctatggaga
    36961 acaaaatgac tactttgacc atactaactg tatcggttgg gtacgttcag gtgctgaaaa
    37021 tcaatcccca atcgcagtcc ttatctcaaa tgaccaagaa aacagcaagt caatgtttgt
    37081 cggtcaagaa tggactaatc aaacctttgt agatttactt ggtaaccacc aaggtcaagt
    37141 tacaattgat gaggaaggtt atggacaatt ccctgtctca gctagatccg taagtgtctg
    37201 ggcagtcaat accatctaat agctcataat aaccaagcta ggtccaagcg gatttggctt
    37261 ttttgtattc acaaaaagac ctacccaaat ggatagatct ttacttgatt acaatttacc
    37321 tgctactgca tccaacaatt cttggatctt aggttggttg cttcctcctg ccatggccat
    37381 gtctggttta ccaccaccac gtccatcgat gattggtgct aattctttga caaggtttcc
    37441 tgcatgaagg tcttttgtct tgcttgctac aaggacattg actttgtcac cgatagcggc
    37501 aactaggaca agaagatcag agtagtcttt ttgtttccag ttatctgcaa aggtacgaag
    37561 ggcacctgca tcggatacag acacttgact agcaatgtaa cgatgaccgt tgacttcctt
    37621 aacatctttg aagatatcgc ctgcggctgc agctgcggct ttttctttca actcagcatt
    37681 ttctttttga agttgacgaa gttgttcttg aagtccttct accttgtgag gtacttcctt
    37741 gacttgaggt gctttcaagg ttgctgcgac agctttaaga gcatcctctt gttcacgata
    37801 ggcttcaaag gcttccttac cagtcactgc caagatacgg cgagttcctg aaccgattcc
    37861 ttcttctttg acaattttga agagaccaat ctcagaagtg ttgccaacat gagtaccacc
    37921 acaaagttca atagagtagt caccaatagt cacgacacga acttccttgc cgtatttctc
    37981 accaaagagg gccatcgctc ccatttcttt agcagtgtca atatccgttt caactgtctt
    38041 aacttcaaga gcttcccaga ttttttcgtt gacttgctgt tcaatcgcac gcaattcttc
    38101 agcagttaca gcttggaagt gggtaaagtc aaagcgaagg aattcaactt cgttaagaga
    38161 tcctgcctgt gttgcgtggt ttccaaggat attgtgaagg gcagcgtgaa gcaaatgagt
    38221 cgcagtgtgg tttttcatga cacggtgacg gcgattgcta tcaattgcca aggtatattc
    38281 ttggttcaag gcaagcggtg caaggacttc aactgtatga agggcttgac catttggggc
    38341 tttctgaaca ttggtcacag tagccacaac cttacctgac tcatccaaga tttgtccgtg
    38401 gtcagcgacc tgtccaccca tttcagcata gaatggcgtt tccgcaaaga taagtgaggt
    38461 agttccttct gatacagctt ctacttctgc attgtcagca acgatagcca ccaatttaga
    38521 agacaattgg ctagcattgt ggttgaagac actttctaca gtgatgtttt gaagagtttc
    38581 attttgcata cccattgagc cacccttgac agctgacgca cgcgcgcgtt cttgttgttc
    38641 tttcatggct gcttcaaaac cttcacggtc tacagtcata ccagcctctt cagcaatttc
    38701 ttcagtcaat tcaactggga atccgtatgt atcatagagt ttaaagacat cttgaccagc
    38761 aatgacagat tgaccttttt ctttcaagtc tgccacaatg ccttgggcaa agtgttgacc
    38821 tgagtgaagg gtacgggcaa atgattcttc ttcgctctta acgattttct caataaagtc
    38881 acgtttctca agcacttctg ggtagtagct ttccatgatt tttccaacag ttggaacgag
    38941 tttgtaaagg aaaggctcgt tgatacccaa tttttgacca tgcatagaag cacgacggag
    39001 aagacgacga agaacataac cacgaccttc atttcctgga agggcaccat caccgatagc
    39061 aaatgaaaga gaacgaatgt ggtctgcgat aaccttgaag ctcatgttgt cgccatcttg
    39121 gtcataaacc ttaccagaca atttctcgac ttcacggata atcggcatga agaggtccgt
    39181 ttcaaagttg gtcttagccc cttggataac ggccaccaaa cgctccaaac cagcgcccgt
    39241 atcaatgttc ttatgtggca attccttgta ttcgctacga ggaacagcag ggtctgcgtt
    39301 aaattgtgac aaaacgatgt tccagatttc gatgtaacgg tcgttttcaa tatcttctgc
    39361 aagcaggcga agaccgatat tttctgggtc aaaggcttcc ccacggtcaa agaaaatctc
    39421 tgtatctggt ccagaaggtc ccgcaccaat ttcccagaag ttgtcctcaa ttggaatcaa
    39481 gtgacttgga tccactccca cttcaatcca gcggttgtaa gaatctttat catctggata
    39541 gtaagtcatg taaagtttct cagctgggaa gtcaaaccat tcagggcttg tcaaaagctc
    39601 ataagcccaa gtgatggctt catcacggaa gtaatccccg atagagaagt tccccaacat
    39661 ttcaaacatg gtatggtgac gcgcagtctt ccctacgttt tcgatgtcgt tggtacggat
    39721 agccttttgg gcattggtaa tacgtggatt ttcagggata atggtcccgt caaagtattt
    39781 cttgagggtt gctaccccag agttgatcca caaaagagtt gggtcattta caggaaccaa
    39841 acttactgat ggttctactg agtgaccttt ggtcgcccag aaatcaagcc acatttggcg
    39901 tacttgtgca ctagatagtt gtttcatatt gtctccttat ttacttgttt aatgtgattg
    39961 gctttccagc atttccacat agtcaatcgc gacacagagg gaaatgacta ggtctgcata
    40021 agcgtcttca agaaccgtta cggtataggt agaggtcaga tggaagagtt ccttcttaat
    40081 ttccgcaatc aactgatcgc gatcatccag caatttgaaa ttcaaatccc agatattgcc
    40141 ctcgatacga agacctagat tatcaaactc atacttatct cgccaaaagg tcaacttctt
    40201 acgaatgaca aaactcgagc catcccgaag ctgaatctca aaacgaggaa gcaaggtcaa
    40261 gatttcttta ctgatctgac tgacttgttc accagccgca tcatagatgg taaaagtttt
    40321 gggaatctta aaaaatgatc cctccacctg ataggcaatt tctcccctgt catccttgat
    40381 agcgaagcgt tcgcctccaa gacgaaactt ttgtttgaca agaaatgttt tcatcaacac
    40441 ctccaaaaat caaaagacaa gctcatatca cgaagggcga aaaaccgcgg taccaccttc
    40501 attcaatgaa cttgtcattc tcttgttctt atgcaattgt atgattgagt agcatgactt
    40561 tctagcttag atggctcgca gcaccgccat ttctctggac taagacaagt gaaaattaat
    40621 tctcaacttt cttattataa cgttttttta agcttgcgtc aactggaaat gatctccgtt
    40681 gaattagacc aattccctac atctctgatt actttttcag gatatatttt ttcttactac
    40741 cgtttttctt tttatcccaa attttcatat tactaaacac agctactaga atatttccaa
    40801 atataaaggt gcctatcacc caatatatgg actcagttgt taggtattgt cgatccaagc
    40861 catcctttaa atggaatagt ataacagttt ggttaacaat cataaaggtt ggccagaaac
    40921 tttttttgaa aaaagtagac attttcatta tttgttgccg ctttctgtaa ggttaatact
    40981 caataaaaat caaaaagcaa actaggaagc tagcctcaag ctgtacttga gtacggcaag
    41041 gcaacgctga catggtttga agagtatagg cttagtatac tactaggcaa gcaaataagc
    41101 aaataaacaa ctagaataga aaaagatagg gctctaaaaa ctgacttcta ttccttaaaa
    41161 acgaaccagc ttgactgatt cgccttctta cgtttatctc ctacttccga tacattttaa
    41221 actgtaggaa gaggtcgcta tatttccctg tccatttatg gtcaaatttc tcataaactt
    41281 ctaggtgttt catggtttca acatcgggat agaaggcctt atcttccttt gtttcctctg
    41341 ggagcaattc cttcgctggt aggtttggtg ttgaatagcc gacatactcc gcattttgga
    41401 gagcattttc aggtttcaac ataaagttga taaaggcata ggctgagttt tggtttttaa
    41461 ctgttttggg aatgaccata ttgtcaaacc aaagattgct ggcctctgtc ggtaccacat
    41521 aacgtagatt ttcatttttt tctaacattt ggctggcttc accagagaag gtcacgccga
    41581 ttgcaacatt attctgaatc atatagccct tcatctcgtc cgcaacgata gccttgatat
    41641 ttggagtcag tttgtagagc ttatccactg tctcttccaa ctgctgcaga tccttggagt
    41701 tgaggctgta gccgagggaa ttgagtccta gtcccagcac ctcacgcgcc ccatcaaaga
    41761 gcatgataga attcttatac tccggcttcc aaaggtcatc ccaatgctca ggcgcttcat
    41821 ctaccatggt ttcgttgtag acaattccta aggttcccca gaagtaaggg atggagaatt
    41881 tattacctgg gtcaaaggac tggttgagaa actctggtcc gatattttcc attccttcaa
    41941 tttttgaata atcaagcgga accaagaggt cttcgtcctt catcttgtta atcatgtatt
    42001 cacttggaat ggcaatatcg taggtcgttc caccctgctt tatcttagtg tacatggctt
    42061 cgttggagtc aaaagtctcg tactgaactt gaattcctgt ttcttctgta aactgagtca
    42121 agagttcagg atcgatatag tctccccagt tatagataac caatttttga ctatctcgac
    42181 tattgatttt actatctaaa tgagtcgcaa ttccccacaa gacaaggata atcgctgcaa
    42241 ttcctgctaa aaatgaatag atttttttca tgcttgctcc tccttctcac gagagataaa
    42301 gtaataacct acaactagga taatactaaa gagaaagact agagcagaaa gggcattgat
    42361 ttctagcgaa atccccttgc gagcacgaga gtaaatctcg actgataggg ttgaaaagcc
    42421 atttcctgtt acaaagaagg tcacggcaaa gtcatctaac gaataggtga aggccatgaa
    42481 ataaccagca atgatagacg gagtcaggta aggaagcatg atttccttaa acatctgaaa
    42541 ttgactagct cccaagtcat aggccgcatg aatcatgtcg ccattcattt ccttgagtcg
    42601 aggcaagacc atcaagacca cgataggaat ggagaaggcc acgtgactag atagaacggt
    42661 caaaaagcca agtgaaaact tgagttgggt aaagagaatc aagaagctag caccaatcat
    42721 aacgtcaggc gcaaccatga ggatattatt gagtgataga aaggcttctt ggtatttctt
    42781 acgagactgg tagatgtaaa tggcaccaaa agtcccgata atggtcgcta tcaaggctga
    42841 taggaaggcc aagaaaaatg tctgagccaa aatcagcatg agtctcccat ctccaaacat
    42901 ggtttcaaag tgagtccagc taaaacctgt aaagctattc atatcatcac cagcattaaa
    42961 ggcatagcca atcaagtaaa agataggcag gtagaggacc agaaagacca gtcccagata
    43021 aaggttggca aattttttca tcgttctctc ctttccttag tcacccacat ggtgatgaac
    43081 atggtcagga tgagaatcac accgatagtt gaacccatac catagttgtc attggttaga
    43141 aaattctgct caatagccgt ccccaaggtg ataacgcggt tcccaccaat caaacgggtc
    43201 agcatgaaga gactcaaact tgggataaag accgactgaa ccccacttcg cacaccgttc
    43261 atagatagag ggaagatgac atgacggaag gtctcccact tagttgcacc aaggtcgtaa
    43321 ctagcattga tgagattatt atccatatcg tctaagacat tgaaaatcgg caaaatcata
    43381 aaggggagct cgatgtagct tgcgacaaag ataaatgaga aatcagtaaa tagcaactgc
    43441 tgtgaaccaa ttccgataaa ttccaagaat tggttaatag agccattctg accaaaaatc
    43501 ccgataaagg cataagcctt aagaagaagg ttgatccaag ttggcagaat aatcagcata
    43561 atccagagtt gacggtgttt gagacgggtc aaaaagaggg ccgtcggata actgataagc
    43621 agtgtcacaa aggtcacaat gcctgcataa agcactgagt tgaaactcat tttaagatag
    43681 gtcaagtttt gtgacgcaaa gtaagatttg taattttcta aactgaactg gccttcgatg
    43741 ttgaaaaagg attgaccgaa aatcaagacc aagggtgcca atacaaagag cgcaatccaa
    43801 agcatgtagg gtactacaaa gagtttagag cttgttttct tcatctcttt cctcctcgat
    43861 tgcattgatc aaacctgctt cttgctcttc gatttctacg tactcctcaa tacgagcatc
    43921 gaactcttct tcggtttcat tgagacgcat gatgtggatg tcttctggtt caaagtccag
    43981 accgatttcc tcacccacga tggccttacg ggttgagtgg atcatccatt catttccaag
    44041 ttcgtcatag gcgataattt cataatgcac cccacggaag agctgggtat cgaccttaac
    44101 ttgaagcttg ccttcttcag gaagggtaat gcgcaagtcc tctggacgaa taacgacctc
    44161 aacaagttca tttggcttca tcccaccatc aaccgcttca aagcgtttgc cgttaaattc
    44221 gaccaagtag tcctcaatca tggtacctgg caagatgttt gactccccga taaaggtggc
    44281 aacaaagtgg ttgattggct catcgtagat gtccacaggg gttccagact ggacaatctc
    44341 gccatcattc ataacgaaaa tccagtcact catggcaaga gcttcttcct gatcgtgagt
    44401 gacaaagaca aaggtaatgc ccaatcgttg ttgcagttca cgcagttcgt actgcatgtc
    44461 tgttcttaat ttcaagtcca gcgctgacaa gggctcatcc aacaaaacca cacggggttg
    44521 gttgatgata gcacgggcga tagccacacg ctgacgttgt cctccagaaa gtttgcggat
    44581 ggaacgtttt tcataacctt ccaactgaac catcttgaga acttccgcta cacgttgctc
    44641 gatttctttc ttatcaatgt tacgcaagcg aagtggaaag gcaacatttt caaacacatt
    44701 catatgtggg aacaaggcat aggattggaa gacagtatgt acgtcgcgct tgttggttgg
    44761 aatatcattg atacgaacac cgtctagcat gatatctcct gtcgtcgcat ccagtaaacc
    44821 tgcaataatg tttaggatag ttgatttccc cgaaccagat gcacctagaa gggtgtagaa
    44881 tttcccttct tccaactcaa agttgatgtc tttgagaacc ttggtgttgc tgtcttcaaa
    44941 aactttagag acgtttttga attcgataat tggttttttc aattggcata aattccttct
    45001 ttttcataga ttaaccgatc ggggctctgt caggtcccca ctacctcttg cagggagtaa
    45061 aaccacctgc atacatcttc gctaccgata ggctttcacc cccctttcca tgacatagca
    45121 gcagcttttc aaatacagct tcctacttgc tttcacccaa gatccggact tctctttcaa
    45181 gcgtaatacc tgagtgttcc ttgacttttt cgataaccga ttggatcaag tcctcgtagt
    45241 ctttggccgt tccatctgcg acattgatca taaatcctgc atgcttttct gacacttcta
    45301 cgccaccgat acgatagcct ttcaagccag cttctgaaat taactgacct gcaaaatgcc
    45361 cgactggacg cttaaagacc gagccacaag atgggtattc caaaggttgc ttgagttcac
    45421 gtaggtgcgt caagcggtcc atttcctgct tgataacctg atgggttcct ggggctaggg
    45481 caaatttaac tgacaagaca actgcaccag actcctgaat agctgaatgg cggtaaccaa
    45541 aagccaagtc tttagcagac agggtttcga tttctccatc cttggtcaag accttacaag
    45601 actgcaatat gtgagcaatc tcgccaccat aggcacccgc attcataaag acagcaccgc
    45661 caacgcttcc tggaatacca caagcaaact caaagccagt caaactatga cggagggcaa
    45721 tgcgagttgt ttcaatcaag ttagccccag cttctgcttc aatggtatag ccatcaacag
    45781 aaacgttatt gagcttgtca cacaagatga caaatccacg aatcccacca tcacgaacga
    45841 tgatattgct tgcattgcca agaaccatcc aagggatatt ttcttggttg gcaaatttca
    45901 caacgcgagc caactcaaaa cgatttcgtg gaaagaccaa ataatcagcc tctccaccta
    45961 cttttgtata actatagcta tgcaagggtt cctgaaaacg gatatcaatt ccttctaaga
    46021 tttcaagcat tttttctctt acagacatgt cactcttcct tttacaaaat tcattccatt
    46081 ataccatttt tagagacatt tgacgaccat aaaaatacct tgtttggatt ttgcataaga
    46141 aaaagaggtt cccccctttt tatgattttt tacaaaagat ttccttggtt ccataggcaa
    46201 ccagaacgag ctccagtgct agaatcactt caaccaagac tggatttgtc aaccagccta
    46261 cttggaaaag agatggtgcc agatcaaaga aggcatgcaa gccataggct gctaggagat
    46321 aaatccattt cttctggcga acagcttggt aaacccaaac tgtcaaaagt aattggaaac
    46381 caagcgccaa gattcgctca aaaccaagca aataaatctg ccagaccgaa agtgactgaa
    46441 tggtttttaa catattttca gacagtaatt gcataacctg tggattctga gtttgaactg
    46501 ccgaaagaac gatgtaaaga ttgagtaaac taataaggcc tagaaaaatc aactccaagc
    46561 caccatgccc taggccatag gccaaggcgt ctgccttttc caaacttctc tttttctcca
    46621 accatttgaa gaaaacaaga cgagccgttt cctcaaaaaa tgctaccatg gctaggccat
    46681 agataatata gataagcgga tgaacttaca agagggcaat actaccgtct ttttgaggat
    46741 gcaaaatcaa gatatgcacc agtttttcca aaatctgcga agagacaaag aaagcgactg
    46801 cacccaagtc caagacagct agattaatct ggtatttctt tttggcaaac caaatgcttc
    46861 ctatcagaaa agctagcaac agcaacatgg taataatgat atgaatggtc attttcttct
    46921 cctattctgc cttttcaata tcttttttca tctcgtcaac attgaactta gcaaacaagt
    46981 attgacggtc ttggactggg aaacgttggt ccaactggtc aactgctccc acctcgataa
    47041 tgccttcctt gatgacaaaa tccatgacat gtccaccgaa ggtcaaatca tctgatatga
    47101 agtgcagatg gtagcctgcc acactgaccc catggaaaat ctcaggcgtc cagaaaccaa
    47161 caatagtccc cacaacattg tcacgactat attccggttg atgggttgcg acatcagcaa
    47221 acttggtatc gggtgttgac ttaggaatca tacgcacatg catatgtgaa aattcccccc
    47281 gaatcttgat agagcggaaa agattttccc catcataata agactcaatt cgttcttcca
    47341 attccttgtc tgtcatctca aagcgctggc ggaaaatgac ctctgcctga tgcggtacta
    47401 ctgctgcata aggaataagg gcatctggtg acacttccac aatttctggc tggtctcctg
    47461 accctttggc ctgataagcc ttgccatcca agacaatcaa ttccccatca atagaatcca
    47521 aggttcccaa accaaggtca ccatgctcta gcaattctcc cactgtcatg gtaccaccat
    47581 aaaggccagc catcaaggct ccaagagtat tgtattgaaa taatttcact ggttcctgca
    47641 cgttcttatc cattcacttt cttgtctgtt attctataaa tcttactcct aagtatacca
    47701 catttgcccc tagatgtgaa cgagagaaac gctctagaca ttgccaagaa ggaaaaaaaa
    47761 gggtacaatg taacaaaatc aagggaggtc tggaatgaag aaacaaagca agtacaaaga
    47821 ggtcgtttcc tatctgaaaa atggtatcga gtctggacga tttccgacgg gtagtcgcct
    47881 gccttctatc cgtcaactga gccttgactt tcactgcagc aaggacacca ttcaacgagc
    47941 cctgctggaa ttacggcacg aacaatatct ctatgccaag cctcagagtg gctactatgt
    48001 attagaacaa gggcaacatc aagacctaga aatcgaggtt accgacgaac atgccagtgc
    48061 ctatgacgat ttccgactct gtgtcaatga aaccttgatt ggccgagaaa actacctctt
    48121 caactactat gacaatcaag aaggattaga agacctaaga cagtccattc acaaactcct
    48181 ctttgagcaa gctctctact gcaaggctaa ccaactagta ctgacttctg gaacccaaca
    48241 agccttgttt atcctctctc aaatatcctt tcctagacaa gccaaggaaa tcttggtgga
    48301 acagccaacc taccatcgga tgaatcgcct cttgattgca caggggctgg actatcaaac
    48361 gattgaacga ggcattgatg ggattgactt ggaggagctg gaaggccact tcaaaacagg
    48421 aaaaattaaa tttttctaca ccattcctag atttcactat cctctgggac attcctattc
    48481 tgagcaggac aaacgatcta ttcttaactt agctgccaag tatgatgtct atatcgtaga
    48541 ggacgattat ctgggtgatt tggactccaa gaagggccaa accttccact atcttgatac
    48601 agaggagcgt gtcatttata tcaagtcctt ctcgaccagc ctttttcctg cccttcgtat
    48661 tacagcactc attcttccaa atgctatcaa agaagcattt gtggcctaca aaaatatcct
    48721 agactacgac agcaacctca ttatgcaaaa ggccctgtca ctctatattg acagtcaatt
    48781 gtttgaaaaa aatcgtttgg ctcgcttgac caatcatgaa tcttaccaaa aacaaatcga
    48841 ggaaaggata actaaaacac cttgtcccct tcctcattat cccctacacg atggtttatt
    48901 gctagacctg agacagtatc ctaaaatcgc cagtctcaaa cacagtcaac tgagcttgga
    48961 cttctttgaa gaggcctatt taagcacctg tccttatcaa tttgccaagg tgtccctaga
    49021 caatctggaa aatgttttaa actatttaaa agcagaattg gaatgacatc caactctgct
    49081 ttttcttatt cttcaacttc agttaaactt gctgcttttt caagatagct ttggtaagtt
    49141 ccttcatcct taagtttttg gatgaccttg tctaccactt ctttcaaatc atcactattt
    49201 tttctaagag caacggcatt ggcgtcgccg tccttcatat tcaagctgac agttgcgaca
    49261 gctaagccag cgtttttagc agcataacta agtgcaacag gctcatccat atgaacagca
    49321 tctacttttc cagcctgcaa ttcattgact gcttcaccca tattagttag ggaagttaat
    49381 tgagcttttg gcaattgttc cttgaccatt gattctggaa cagtcccttt ttgggctgca
    49441 atattagcac tttctaggct agttaaatcc ttgtattttt ccacatcagc cttacgaacc
    49501 aagaaactaa tcttgttttc atagtatggg attgaaaaat caaagacttc ttttctctcg
    49561 tcagtagcac taattcctgc aactgctagg tcagccttac cagtttgaag actggtcaaa
    49621 acattgtcaa aactcatgct tgagatttcc aacttaaccc caagttcatc agcgatagcc
    49681 tgagccatgt cgatgtctgc accgactacc tggttctttc catcaaccaa tgattgaaat
    49741 tcaaagggtg catagtcagg actggttgcc acaactaatt tccctttttg tttgatagca
    49801 tccacagcag actgagaacc attagaacct gactggcaag ctactaagaa gaaacttgca
    49861 agaaaattac ataaaacaaa tatccatttt tttgatttca taaataaaca acctctctgt
    49921 taattttgta taattataac gatatccaag ttacttgtca agtgtttttt aaatttttat
    49981 ctcaaaaata ttttttcgtt caaaaaaagg agccatcagt tgatttcaag ctccttttta
    50041 tacagaatta aactatttta tagttcgaca atcttacctg tttcaaagta gacaacccat
    50101 tcacagatat ttttagcata gtcaccgata cgctccaagt aggaaataac ttggaaataa
    50161 tcacgacccg taacaatggc ttctggattt ttcttaatct cttcagtcgc aaggtcacgg
    50221 atagtttcaa aatagtggtt aatttgctca tccatggagg ccacccggta tgcgtcgtca
    50281 acagaaccat taagataaag atcaagtgct gcttcaacaa cgcttttaac ttcacgtccc
    50341 atttttttaa tttcttcctc tacagctgga atgcgttctt cccccttcat acggatggtt
    50401 gcctgggcaa tggctacagc gtgatccccc atacgctcca catctgatac agccttaagg
    50461 acagtcaaga ctgtacgcaa atcttgagag actggttgtt ggagtgcgat catttcaaat
    50521 gatttctttt ccagtttcac ttcgtattca tttacttctg catcatcttc tatgacctct
    50581 tttgccaggt cacggtcatg cgtgacaaaa gcacgtaccg tacgattgat ttgtgagagc
    50641 acttcttgtc ccatagcgta gaactggtta tgtaatttct ctaaatcttc ttcaaattga
    50701 gatcgtaaca tctttcatct ccttatccaa attttcctgt aatatagtct tccgtttcct
    50761 tgtgttgggg attaaggaac atctgcttgg tatcattaaa ttcaatcaaa tctccatcta
    50821 ggaaaaatcc tgtcctatca gagatacgtg aagcttgctg catggaacgg gttaccagaa
    50881 gcatggtgta cttgtctttt agaccataca aggtttcctc aattttacca gctgaaatcg
    50941 gatccaaagc cgaagttggc tcatccaaga ggatgatttt aggactagtt gccaagacac
    51001 gggccacgca gacacgctgc tgttgaccac ctgacaatcc aatagctgaa tcatatagac
    51061 gatccttgac ctcatcccag atagaggcac cttgcaaggc tttttctacg gcttcatcca
    51121 gaacctgctt atccttaatt ccattgatac gaagcccgta gacaacattc tcatagatag
    51181 tcatagggaa aggattaggt tgttggaaaa ccattccgat ttccttacgt aattcaaccg
    51241 tatctgtacg cggactgtag atgttgtgac cattgtacac cacggatcca gttgtggtca
    51301 cctctggatt gagatctccc atgcggttga gagacttgag gagggttgac ttccctgatc
    51361 cagatggacc aatcaaggct gtaatttcct taggttggaa agatagggaa acactattca
    51421 aagccttctt tttattataa taaacggaca ggtctgatac ctgtaaaatc gcatctgtca
    51481 tacggtttcc tttctaacca aagtgaccag atacatagtc attggtggac tgtagcttgg
    51541 cattttggaa aatagttgca gtcttgtcat actcaatcaa atcacccaag taaaagaagc
    51601 ctgtatagtc acttgcacga gcagcctgct gcatattatg cgttacaatg atgatggtaa
    51661 agtttttctt gagctcaaac atggtctctt ctagttgcat ggtcgcaatc ggatccaagg
    51721 ctgaggctgg ctcatccatt aagaggatat ctggcttaac agagatggca cgagcgatac
    51781 agagacgttg ttgctgacca cctgataagg tcaaggctga cttgtggaga tcgtctttaa
    51841 cctgatccca aagggcagcc tgacgaaggg aggtttctac gatttcatct aggacttgct
    51901 tatccttaac tccagcacgt tcatgcgcaa aggtaatatt acggtaaatt gacttagcaa
    51961 atggattggg acgttgaaaa accattccaa tgtgtttacg catttcataa acgttgattt
    52021 ctggacggtt gacatcaatt ccacgataga gaatctgccc agttacttta gcaatatcaa
    52081 tggtatcatt catgcgattg agactgcgta agtaggtaga tttccccgat cccgacggac
    52141 caatcaaagc tgtaatttta tttctttcaa attgcatatc aatcccctta atggattcat
    52201 ttttaccata gtaaacatgg acatccttag tagaaagggc tactttttct tcaggaaagg
    52261 taaggatatg cttctcatcc cagttatatg ttgacatggc ttctccttta ggcagcggtt
    52321 aatttcttgt gtagatagct tccgaactta cgagctccaa agttaaaaat caggataaag
    52381 atcaggagca cagcggcaga acctgctgat acaatggttc catctggaat agtgccttca
    52441 ctattgactt tccagatatg gacagccaag gtttctgctt gacggaagat agagatgggg
    52501 ctagtcacac tgaggatatt ccagttagac cagtcaagag ctggcgccga ttgccctgct
    52561 gtatagatca gagctgcagc ttcgccaaag atacgaccag atgccaagac gacacccgtt
    52621 acaatacctg gaagcgcttc tggaataaca acatgaacca ctgtctccca gcgagaaatc
    52681 ccaagagcca gaccagcctc acgttgggta tggtgaacgt gtttcaaact atcctctaca
    52741 ttacgcgtca tctgaggcaa gttaaagact gtcaaggcca aggcacctga aatgattgaa
    52801 aatccatact caaactggac tacaaagatc aagtaaccaa agagacccac caccactgat
    52861 ggtaaagagg acaagatttc aatacaagtc cgcacaaagt tggtaacagg acctttttta
    52921 gcatattcag ccaagtaaat cccagctccc atagaaagag gtacagaaat aatcaaggta
    52981 atgaccaata ggaaaaagga attgtaaagc tgaatgccaa tcccaccacc tgcttgaaaa
    53041 gcagaagacc ttccagtcaa gaaagaccaa gagatatggg gcaagccccg aaccaagata
    53101 tagagaatca aggaagccaa gattgtcaca atgatgctag caatcgtata gaggacagct
    53161 gttgcaagtt tatctaattt cttagcgcgc ataatttttc tttcctcttt ctttcgtaat
    53221 caatttaatc acactgttaa aaactaaact catcaagagc agtaccaagg ccagtgacca
    53281 gagaacatta ttatttacag ttcccatgac agtgttccca attcccatag ttaatataga
    53341 agttaaagtt gcagctggtg tggtcaagga agttgggata acagctgagt ttccgacaac
    53401 catctggata gctagagcct caccaaaggc acgcgccatc ccaaagacca ctgcagtgaa
    53461 aataccagaa cgggccgcct tcaagatcac acgccagata gtctgccagc gagtggctcc
    53521 catagcgaaa ctggcttcac gataataacg aggaaccgca cgcaagctat ccgttgtcat
    53581 aaaggttacg gtcggcaaaa tcatgacaaa gaggacggaa atccctgaca aaatcccaaa
    53641 accagtccca ccaaagacac tgcgaacaaa gggaacgacg acttgcaagc caataaatcc
    53701 gtacactact gaaggaatcc caaccaggag ttcaatagct ggttgcaaaa tcttcgcccc
    53761 ttttggtgat acttcggtca taaaaactgc tgcaccaata gcaaagggtg ttgcgataag
    53821 ggctgagaga atggtaacga taaaggaacc caaaatcata ggaagggcac caaattcttt
    53881 actagaagga ttccaaattc ctcccaaaag aaagtcaaag atattcacac cattgacaaa
    53941 gaaggtcgac aagccttttt gcgctacgaa aaccaaaatc atggccacaa ggatgactat
    54001 caaagaaaga caggcaaagg tcaaaccttt tcctaatttc tccagacgag aattctttga
    54061 tggaagcaac attttcttag ctaattcttc ttgattcatt attgtctccc ttccaacact
    54121 gtcacagttc cggcagcatc tttttcaacc ttcatttcct taatcggaat atacttcaat
    54181 cctttgacaa tcccttcttg ggtctcatcc gagagaacaa aattgagaaa ttctgcagcc
    54241 aactcattgg gctgccccaa tgtatacata tgctcataag accacaaggg ccaattattg
    54301 ctacttatat tttctggact taagtcatag ccattcaact tcatgctttt gaccgaatca
    54361 tctatatagg taagagataa ataagagata gctcctggac tttttgatac gattgatttt
    54421 accgctccat ttgaatcctg ctcctgactt tgcatggcag actgaccttc cataatgaca
    54481 gtatcaaagg tagcacgaga gccagagccg gctgcccgat tgataacaga gatgggtaag
    54541 tccttaccac caacctcttt ccaattggtt acctcaccta tgaagatttg acgaagttgc
    54601 tctgtcgtta ggttatcaac atcaacctcc ttattgacaa tcagagccaa gccagctacc
    54661 gcgaccttgt ggtcaacaag agcagaagca tcaattccgt ctttttcctc agcaaataca
    54721 tctgagtttc ctatatcaac tgccccagac tgaacctggg acaagcctgt accagaacct
    54781 cccccttgga cattgaccgt ttttccaaca tggatcgtgc caaattcatc tgccgctact
    54841 tcaaccaagg gttgcaaggc agttgagcca acagccgtta tggattctcc acgatcaatc
    54901 cagctagcac agcctactaa acaagccgtc agccaaaaag cgataagaga cagagcaagc
    54961 ttttttcttt ttttcactgt ttttctcctc gaaaataatt atgaatactg tgaatttttt
    55021 aagtagttct ttatgagttg acgcatgaat tcttaccaaa tttctgcgca attgattatt
    55081 tatataatat aggctatatt actctttcct aacctccttt tttcatatgt ggataaaatc
    55141 tcttgtctat cccttccccc attgtcaccc attatagtca tttcgtgtct ctttttcccc
    55201 tttttaatgc aagggaaatt actcttctta gatgataatc caaaagctag aaaggtatct
    55261 caaacctctc tactctccca gactagttta caactaaaag gaaaagattc tattttatga
    55321 gaaatctagt ttacaagcgg taagaacgct aataactaaa cttcttgtac tctttgaaaa
    55381 tctcttcaaa gcagtgtttt gagctatcta tggctagctt cctagtttgc tctttgattt
    55441 tcatcgagta gtaaaactac atgtgatggc aatcaagata tcaagaatca tcctactaaa
    55501 aaaatccata ctttcactat aacatagaat aagatatttg actagcattt tcatttgaat
    55561 ctgaggcctt ttggaaaata atttttcaaa acatttccag taacctttgc aaagcccaag
    55621 ccattgcctt taaccaaaac ttggtaccaa ccatttggca gactttctgc cagctgaacg
    55681 gtttctccag ccgcatactt gacaaacgct tcttggccaa tttcaaccga ctgttcgacc
    55741 tgactcggtt tcaaggctaa accaagagcg aaactgggct caaagcgttt cttcttaaaa
    55801 gtacccagat gcagtccatt gcgagcaatc ttgagcttcc ctaaatctgg caaaagttct
    55861 ggcaagagat aaagctggtc tccaaaaatc tgcaagatac ccggtagatt gaccttcaaa
    55921 tggttttggg caaattcctg ccacaaggca acttgttcac ggctgaggtt actcttactt
    55981 gccttaaatt taggagctgg attgttaccc ttaaactgta gatgggcaac aaactgaccc
    56041 tctcccttaa actgatgagg gtacatccga gccgtttctg gcaggtcaat accagctacc
    56101 attccattga tatgctctac tggcaacaag tcaaaatcat actcttccag caaccaattg
    56161 acaatctctt cgttttcctc gggtgcccag gtacaggtcg aataaaccag acgaccacct
    56221 tcagctaaca tggtcactgc atcctccaga atttctcttt gcaagctagc acattgactc
    56281 ggataatcta agctccaata gtccatagca tcaggttgct tacgaaacat tccttcacca
    56341 gagcaagggg catcaagaac gattaagtca aaatagcctt taaagacctt gaccaagcgg
    56401 tcggcagatt cattggtcac cacgacattt gtcgctccaa aacgctccat gttttcaacc
    56461 aaaatcttag cccgtttgct tgaaatttca ttggaaacaa gtagcccctc ccctgctaga
    56521 taggctgcca gttgagttga tttgcccccc ggtgcagcag ccaagtccaa gaccttcata
    56581 ccaggactgg gttgggctac ttgagccacc atttgagcag caggttcttg cgaataaact
    56641 aaacctgtag catgctcagg cgatttccct gaaaccttcc catagtggcc ccaaggggtt
    56701 tgagtaatgg catcagaaaa ggaaagttgc tcttctttta agggattgac ccgaaaggcc
    56761 gaaaccgctt cctcctcaaa agaggcaaga aaatctcttg cctcatctcc tagtatttct
    56821 ttatattttt caacaaatcc ttctggaaat ttcatttaag ttcttttcct ttcgtaaata
    56881 taggactgaa tttcctcctg catctcaaga ggcaccatca tgaccggctg tctggtttga
    56941 aaatcaggag cttcaccaaa aagggtcaca acccgatagc ccagactttc ccctaaaata
    57001 ctagctgcgg cataatccca tggttgcaga taggtgagat aggtcaacaa atgccctgac
    57061 aaaatcttgg caaaactaat ggccgcactt ccatagacac gaacaccaag aaccgctcgg
    57121 ctcaaatcag ccagccccca ttcattggtt tccagcatac cactattccc tgcaatgaga
    57181 aaatctccaa gtggtttagt tttaaaagga gctaggggcc tatcatttag acaaactgga
    57241 aattccccac caccgtggta acaatcccct ttgaccacat cataaatcag accaaactgt
    57301 ccctgaccat tttcaaaata agccatcata acagcaaaat cttcctgctg ggctacaaaa
    57361 ttattggtac catcaatggg atcaatgacc caaaccttgc cctcttgaac cgaggctcgc
    57421 agacaacctt cttcagcaca aatcttatcc tcaggataac gggacaaaat ctcaccaacc
    57481 aagagttcct gaacttcttt gtccagtctg gtcaccaaat ctgttggaga ggacttggtt
    57541 tcaacacgca agtcttcctg catatggtca agaatgtact ggcctgcttt cttaacaagc
    57601 tctttagcaa attcaaattt actttccaag agaaatcttt ccttcccctt tttctttggc
    57661 agcctgaact gctcggtaaa gtgaatagcc actaaccgtt tcaaattctc gtcccaaacg
    57721 tttctcttcg ctcttgcttg gcacgacctc tttgaatccc ttataggagt ccagtaactt
    57781 tttagcctct actttgcttt cataggcagc ttcaacatca ttaaaaaaag aaagcactga
    57841 agcaagttct tcagtgctcc acgacaaatc tagtgggtaa ctatactgtt tgttcattaa
    57901 ctaataccag ctctcattct tgcttctttt agttcttgct tacgataact acgagggaga
    57961 aaagcacgaa tctcatcttc attaaaaccg atttgcatac gcttggcatc aataataatt
    58021 ggacgacgca aaagactagg atactgctca atcaaatgaa gcaattccga taccgaaata
    58081 ctctctacat caatattcaa tttttgaaaa atttttgaac gagttgaaat gatgtcatca
    58141 gtaccatttt cggtcaagga aaggatgtgt tgcaattctt ttcttgttaa aggactggtc
    58201 ataatattgt gttccacaaa gggaacctta tgtttttcta accaggcctt agccttacga
    58261 catgatgtac agctcggtga tagaaatagt gtaatcatgc ttttctcttc ttatctatac
    58321 tttgctactt ctattataca aaaaaataaa gcgcttgact agggattttt agaaaaaaag
    58381 cctatttttt caagaaaaat aggctttttg cgaacgattg acacaattgg atttggttaa
    58441 ttcactctta acgatggttt taaacgatat atatttttat atatgtaaat taaaaacatc
    58501 tttcctttca cttcctacga cttttcagat acagatagcc aaagaagttt tcatagaggg
    58561 caaaaaagag gaggaaggca tgaagaaaga aggtctctgg caaaatcata ataacaggat
    58621 ccttggctgg atcaaaaagc caggtatcat ctcccacaaa gagaatttga tggaaaagag
    58681 taaagaattg gtcaaaacca atcaaaactc ccccaagtcc aatcatcaca ggtaagacta
    58741 ctagagccag gagacttttt cgataaagag acaaaaagtc ctttttcaca atcctattga
    58801 caaagacata gaaacttggc agtgtcacta gagctactag ctgaaccaaa tgaaagagat
    58861 tcttgaccac tgcgaaatgg tgcagaccag ctgctgacga acgaaaatca ggcatctgta
    58921 agacctgact aaaaggattg gtcagataat tcatcaagat atgaaaattg tattgaatgg
    58981 tttctggttt tagatagact cgattcgtta agtttagcca ctgaatctcc ataggataga
    59041 aaatccaagc cagataaatg gtcagaagga ttgagaggga gaggagaaag agcatagagc
    59101 cccaaaaggt caatttagtt ttcatcaaaa tcccactccg caaggctaga aaccacatgt
    59161 gtcggtgcga ttggcaggcc agctacttct tctgccttag taaaacctgt cgtcaccaag
    59221 agcgttggaa tgccattgtc aatcccagcc cggatatcag tcaaataatt gtccccaacc
    59281 atgattaact cttcacgttc caaacctaag tgctcaaccg ccttgtccat aatgatggca
    59341 tttggttttc cgatataaac cggcttcact cgtgtcgcta cttcaagcag cgtaatcagt
    59401 gagccagcac ctggcaaaag accacgttcc gtcgggatgt tgaggtcagg attggttccg
    59461 ataaaatggg cacccttttg aatagcaaga gttgctgtgg caaatttttc atagtcgact
    59521 tgccaatcca gaccaactac cacgtaggca gggttttcct tgtcttccac ataaccagcc
    59581 gccttgatgg cttccttgag tcctgcttct ccgacgacat agacagtctt ttcaagcccc
    59641 aaatcattca tatagtcgat ggttgccaaa gtcgctgtgt agacagtcga tagaggcgta
    59701 tcgatattaa aattctgagc caacatctcc ttaacactct ctggagtgcg ggttgtattg
    59761 ttggttacaa agagataggg aatgtcccgc ttttgcaatt catgaacaaa agtctctcca
    59821 gcagggattc ggtctttccc cttataaatg gttccgtcta aatcaattaa atagccttta
    59881 tatttcatct atttctccct aaaccttttt tatttcttgc caagtaatga ttgcttgggc
    59941 attgataacc ccatcacttg taatttcatg cttgctttcc agtccagtcc gttcaacagc
    60001 cgatgtaatc accccacctg gtcgaacttc cttgacatac ttgaggttga ttttcttggg
    60061 aatatagtgg gtcaaaaaat ccgctcccat gacctcaaaa atccagtcca agtatttact
    60121 gttattgaca tgaccattca tatccaagtc gtaaaaacga acatggtaat ccttgctgat
    60181 cggctcttcc aaggattcat acttcggtcc acggataagt tttttatcaa aatcagactg
    60241 gtaaggagcc acaatctcag gttcaacagc atggactttt cgactgtcgc ggtccatgag
    60301 aacaaaggtc gccatcatat ggatgagctc ctgccccgct tcattataaa tagtaaagcg
    60361 acggtagcaa aaaagtcgat tgtagctcaa ggcttccgtt tcgatggtaa tttcttccgc
    60421 aaaacgaggc aaacgaacca cctcaatatc atattctgcg ataatccaga ccagattata
    60481 gtcttccaaa atggccttat cactaactcc cagttcaatc gattgcatcc ctgaaacttg
    60541 cagtgacagc aaaatcacat ctggaagttt gatatgaccg ttcatatcag ccatatcaaa
    60601 aggaattttc attttcattt gataagttaa gcacatgatc ctactccaaa ataaatcgtt
    60661 ctgctacagt atctcccaaa aagagacctc tctttgtcat gcgaacgtgg tcaccctcaa
    60721 tctgcatgag gccttgttga accaaatctc tgacaatttc tccataaagt ccagcaaaag
    60781 actgtccaaa tttttcctca aatcgcgcca tggaaacccc ggatttcttg cggagtccca
    60841 agaacatttc ttcttccatt tgctcctttt gactcaggtg atcttctgta atacaagcat
    60901 tgccttcctc aaccgcactg agataatgac gaatgggacc atgattttta tagcgtactc
    60961 cattgacata accagatgcc cctgcaccaa taccatagta ttcagcattg tcccagtaca
    61021 tgagattgtg acgactttca aagccgggtt tggagaaatt agaaatctca taatgctcaa
    61081 aacccgctcg ctccagctct gcaatgatgt actcaaacat ctccgcttct agttcctcct
    61141 taggcagagg caatttccca cgtcgcatcc ggttcataaa gaccgtatgg ttttctaaaa
    61201 tcaaactata caaactcatg tggggaatat ccagtccaat ggctttagcc acattttcct
    61261 ttacttgctc catggtctga ccaggcagag cataaatcaa atcaatggag atgttgtcaa
    61321 aaccagccag tttcaggcga tcgatatttt cataaatatc cttctccaaa tgactgcgcc
    61381 caatcttttt caacatctta tcatcaaagg tctggacacc tagcgaaaca cgattgacag
    61441 ccgaattttt caaaacagct atcttatccg catccaaatc gcctggattg gcttcaatgg
    61501 tcaactcttc caagacagac aagtccaagt ttttagtcaa gccattcagt aacacctcca
    61561 gttgcggagc cgacagggct gtcggtgttc caccaccgat ataaagggtt gacaactttt
    61621 caatatcata agaacgaaac tcttccagca gatgctctaa atagctgtcg actggctgat
    61681 ttttgatgaa gacctttgaa aaatcacaat aataacaaat ctgggtacaa aatgggatgt
    61741 gcacataggc tgacgttggt tttttctgca tagtaattat tataccacaa agactagatt
    61801 ccagataaaa atcaccatcc ccagatacat agtccgtccg gagatggtga tggtttattc
    61861 ttctgttata tcaatcacaa tctcttctga gtcatcaaga gcttcggctt tttcttgcca
    61921 ttgctccttg agattattta attgattttt tgatgcttct gtcgcttgaa aagcatagga
    61981 tttagcttga gcaagtatac tgtccacagt gatttcacct gactcaacct gttcttttgt
    62041 tttcagaaca aaatctgtag cctgctcctt aacttctgtc agtttttcac agacttgctc
    62101 cttggcatac tccggatctt ctctcaaatc atctagaaaa tcttgagcct gactgcaaac
    62161 ttgtttgccc ttatcacttg ttaaaaacaa ggcaagagct gcacctgaaa cggttcctaa
    62221 aaggattgag gataatttac ccataaggat tctccttttt tattttttga aaaatttact
    62281 tgcaagacga agagctgaca gacttgcacc agtcttgagt gtttttgaac cagctgatga
    62341 agctttcttg ctcaagacac gcgcatggtc attgaggtct gaaacagata gagataaatc
    62401 tgcaacagca ctgaagagtg gatcaatcgt agccaccttg acattgatat catctgccaa
    62461 gacattgacc ttagccaaca actcattggt gtgatgcaag gtcacatcca catctgaagt
    62521 caaggtttta atcgtctttt ctgtttcatc gatgacacga ccaagctttt gtacagtaat
    62581 gatcagatag accaaaaaga caatcaaagc tagggcaaca agaatatatg caacttctaa
    62641 catttagttt tcctcctctg taatatagta aggggccttc tttcgatttt gataaataac
    62701 gatcattata ccgagaccga taaagacaac tgacagccat tgggacactc gaaggctgaa
    62761 gaacatgaga ctatctgttc gcataccttc gatgaccata cgaccgaaac cataccaaat
    62821 caagtaaaag gccgtgatat gacctcgtct gagactcttc catttccgtc taaaaatcag
    62881 aatcaaggca aagccaagca gattccatag agactcataa aggaaagtcg gttgacggta
    62941 gctcccctca atatacatct ggtcacggat aaagccaggt agataatcca gattatccac
    63001 tgttgcacca taagcttctt ggttaaagaa attaccccaa cgccccaaac tttgagcaat
    63061 cataacgcta ggcgccgcaa tatctagaaa atcccaagta ttgatgagtt tacggtcagc
    63121 aaagatatag agcacaagag ccccagttat caaaccaccg taaatggcca aaccaccatt
    63181 ccaaatggca aaaatctctc ctaaattctg actatagtaa tcaaatcgga aaataacata
    63241 gtagagacga gctcctaaaa tagccaaggg aaaggctact aagataaaat ctaaaatatc
    63301 gtctggtatg atcttctttc taggtgcttc tttcatggtc aaataaaccg caagaatcaa
    63361 gcctgtcaca atacataagg cataccaacg aatggctagg ggtcctagtt gaatagcaat
    63421 tggatcaagc attttgcacc tcatttcgag ctatgagact tgtcagtcgt tcgtcgaaca
    63481 aacgggtagc atcaaagccc atttccttgg cacgataatt catggcagct gcctcaatca
    63541 caacagagat attacgacct gttttaactg gaatacgaat acgaggaatg gctacgccag
    63601 aaacttcaag ttcctctgca ttgtttccaa gacgatcaaa ggtcttatgc gtatcgtaat
    63661 tttccaaata gacagcaagc tgaacctgtg aagaatcctt gacagcactc gcaccgtaga
    63721 gactcataac atcgataata ccaaccccac gaatttcaat caagtgtttc aaaatttcag
    63781 ctggttcacc ccagagagta atctcatcct tggcaaagat atcgacacgg tcatcggcta
    63841 ccaaacggtg accacgtttg acaagctcaa gacctgtctc gctcttacca attccactat
    63901 ctccctgaat caagacgccc atcccataaa tatccatcaa gacaccgtgc acactggtac
    63961 gttctgccaa acgagaatcc agatagctag ataactctcc agataaacga ctggtagctg
    64021 cacggctggt taaaatagca atcttacatt ctctagcagc ctttaacatc tcctctggaa
    64081 ccaccaaacc acgggcaaca atgactgctg gtgtctcagg tagaaacatt tttttcaaaa
    64141 cttcataacg gctgttggaa ggcatgctga tcagataaga ccactccttc atccccaaaa
    64201 gttgaatccg ctctggtgta tagtagtcaa aatagcctgt catttcaaga ccaggtcgcg
    64261 taatatccgc tgtattgatt tccttttcaa gcaattctgg ttcaccatag acaatatcta
    64321 gtctaagctt ttcaatcact tcttttacta aaaccgacat catttcctcc ttcaaatgaa
    64381 ttcttctctc tattatatca aattgtagga ggaagtttca gatttttgca ggctttggag
    64441 tatttattta aaagaaaaag gactagattt ctctagcctt tcatttcaat tagaattttt
    64501 tacgtttacg agctacttct gatttacgtt tacgttttac agaaggtttt tcatagaatt
    64561 cacgtttgcg tgtttcttga agagtaccag ctttagtaac cgcacgtttg aaacggcgaa
    64621 gtgcgtcgtc aagagattca ttcttacgta ctactgtttt agacattttt ttcactccct
    64681 tcaagttcaa tatctatttc attctacacg taaaaggaat aattgtcaag caaaaatgcg
    64741 gtttaatttt gattttttct tccatttata caagagttga aagcgttcaa tagaacattg
    64801 cttttttatt tttcgagtaa gctaagcgct tcagcatctg cgatgatggt tacatcaggg
    64861 tgattttgga ggctacttgc aggtaggttc tcagtcactg ggccagatac tgttccggca
    64921 atggcttctg ctttcgactc accataagca aaaagaataa tagacttggc atccaaaatg
    64981 tttttaatcc ccattgaaat agcttgggtt gggacgtctt caatcttggc aaagaagcga
    65041 gcattggctt cgatagtaga ctggtcaagt tctactagat gcgtttgact gtcaaatgga
    65101 gtaccaggct cattaaagcc gatatgccca ttgcgaccga ttcccaagat ttggaggtca
    65161 actggatggt cagccaaaat ttggttgtag cgttcaactt cagcttcagc attgtcctta
    65221 acaccacgag gcaagaaact ttctttaaat ggtttttggt tgaacaagtt ttcttgcatg
    65281 aagtaacgat aagactgtgg attgtcccca tcaaggccca catactcatc aaggttgaca
    65341 ctggttagat ttgaaaaatc aaggtcactc tcaacaattt ccttgtaaaa ttcaagtggg
    65401 ctacttcctg tcgcaagtcc tagagtttga gctccattag ccaatttttc cttcaaaatc
    65461 tcaaaagcaa cttttccacc ttgaacttgg ttttcaactt taataacttt catcttttca
    65521 tcctccattt ctgtctatat ttattatatg gtatagacca atttttgtca agtgaaaacg
    65581 atttaatttc taaaaaaaga gcgtccaaac ttgaaacgtg ttataatgga taggattaga
    65641 acttagaaag aatgaacaaa tatatgaata cagctgattt tgatttccac ttgccagagg
    65701 aattgattgc ccaaacgccc cttgaaaaac gtgatgcctc caaactcctc atcgtcaacc
    65761 gtgagacagg agaaatgcaa gataaacatt tccactctat tattgatatg ctggaacctg
    65821 gtgatgccct tgtcatgaac gacacccgag ttctccctgc ccgcctctat ggtcaaaaag
    65881 tggagacagg aggtcatgtg gaacttctcc tccttaagaa cactagtgga gacgagtggg
    65941 aagttctggc taaacctgcc aaacgcctca aggtcggtac tcgtatcagc tttggtgatg
    66001 gccgcctcag cgctgtcgtt acagaagaat tgacccacgg gggacgcatt gtccgctttg
    66061 aataccaagg aattttccta gaagtcttgg aaagtctggg agaaatgcct ctgccacctt
    66121 atatccacga aaaattagat gaccgtgaac gttatcaaac cgtctacgcc aaggaaagcg
    66181 gctctgctgc agcaccgact gctggtcttc acttcaccaa agaactgctg gcagaaatcc
    66241 aagctaaggg tgttcatcta gtctatctga ctctccatgt cggactcgga acctttagac
    66301 ctgtttctgt ggataatctg gacgaacacg aaatgcactc agagttctat caactttctg
    66361 aggaagctgc tgccaccctt cgctctgtca aagaaaatgg tggtcgcgtc atcgctgtcg
    66421 gaaccacttc tatccgcacc ttggaaacta ttggttccaa gtttgatggg caaatccaag
    66481 cagattctgg ttggaccaat atctttatca aacctgggta tgagtggaag atcgtggatg
    66541 ccttctcaac caacttccat ctgccaaaat caactctggt catgttggtt tctgcctttg
    66601 caggccgtga attagtctta gatgcctacc accatgccat ccaagaacac taccgcttct
    66661 tcagttttgg tgacgccatg tttatttatt gagaaagaat ttctctaatt cttctaatac
    66721 caataaatcg ctaagatatt atttcaaaga acatctacaa ttgaaactct agctagctgt
    66781 agaagacgcc tagtacattg aaattaaaat gcttccccct agcttcgaaa atattgccat
    66841 agattgcgtt gactctccaa attgattcat ctatatttta tttcagcttc ctatattttc
    66901 ttcgctgttt gtaaatcaaa atgcaagaca catgagtagc accatatttg ttactcttat
    66961 ctgtcctctc aagagactat tatgagttat ttcagaatca ttcactactt tgaccctgac
    67021 tctccttagt ctcaaaatca aagacttata ctctccaaaa atctcttcaa accgcgtcaa
    67081 cgtcaccttg gattatatat tcgtcagttc tatctacaac ctcaaagcag tactttgagc
    67141 aacctgcgac tagttttcta gtttgctctt tgattttcat tgagtattaa acaaaaagtg
    67201 aacaaatctg aattctaatg tacagaagac taggcttgtt cactttttta tagtcgctat
    67261 aagatgacct tatctatagc tttttatata taattatata ttcagacata ctattatcaa
    67321 ttttgtcgca gggaggaatc tgttaacgca cccattcacc attatcattg actctatagc
    67381 catctatact tgtattgacc gctaactcac ccgatgcatt tacataatac catttaccac
    67441 caacttggaa ccattgattg actttcatag aaccgttgct gttgaggtag taccatgaac
    67501 cattaacttg tacccaacct gttgccatgg aaccatcagt attataaaaa taccacatac
    67561 cattttcttg tttccagtct gttgttggag caactgcttt agctggttct actgctacat
    67621 ctgttccttg gttagatgta acagatacag gatacgaagg aatagatgat tgctcaggaa
    67681 caacaacttt ttcaggttct ctcgtccctc tccttatacg tctttttacc atctctttag
    67741 taatttgacg agaagtagtt tcttcaatta ttccatcacg ttcatctaca gtatagattg
    67801 tagtaagagt aatttaccaa tttctcctac ttcttctact tcttgacttt tatcaagagt
    67861 tgggccatcg agatattctg tttcgattgg aatttcttgg acaagaactt ggggcttggt
    67921 tcctttttta acaactcttg tttgagagtc tttttttgac ttaaagtact ctcagttact
    67981 tgtccactct ttccatctac attataagtt atcgttgtaa ctgttttccc attctttcct
    68041 agagtaatct cttgctcctg tcctgcagaa aggtcattgt ctgcttcata tttagtagca
    68101 aatggaacaa gaacttcttc aatcttgctt ttagctggaa ctttgataac tgtatccgtg
    68161 gcttcttttc tatcaacagt aacctgttcg gtaacataac cagtctctgg attaacatcg
    68221 taggtccttg tcgtagttac atagccatcc tctccgtcaa ttgtaacagg attttcacta
    68281 cggtcttttg tttcatcttt ttcaaaacga attcgcgtac ttgaaatttt cttggttact
    68341 accttaggtt tagtcgctac ttttacaata atatccccat tgtcagcgtc atcatactct
    68401 attccctctt ctttatctct agtatcatct ctgacatatt gaatcccatc agcagcatga
    68461 gcaaaacttg tattcagatt cctcctaaaa ataaagttag cccgattatc gcagaaccaa
    68521 aaatctttcc gagtttacgt attgcataac gcttattagt attagatttt gccattacat
    68581 cctacttcta gtatagcatc ttttctatca aacgttaaac aatatacttt atatataaaa
    68641 tagacttaga atgatatatt gattattgaa ctaacacttt aactatatcg taatcaatct
    68701 catatataaa ggattgcaga catctgatct aaatacatgc taatatattt agatacaaac
    68761 attccaactt gataattttc actcatcttt caacattcct tacacaacga tgcagtataa
    68821 atagaatagt tttctcatca gaatgagact attttaatat tagataattt gatagaaaaa
    68881 aacataaata aaattggttg aatttaattc cctaactcga tagaggattc tattttaaat
    68941 ttaacaacag ctaggattac actataaaaa gtacattacc acctgttcgg ctggagaatc
    69001 tagtcgatta gctccctctt agttacaagc ttaaagcgat tttttaacta atactaaacc
    69061 agattaaaga aggaactaga acatctgtct tgtactaatc aatatgctat tttaaaattg
    69121 caaataaact tggaatgcta attattatat ttacaataaa tagttgactt cgatagaaac
    69181 agaaaataga attcaacatt cttccctact tataccataa taaataagat ccgcaagata
    69241 gccttttctc tctacaccat taacaatggt ttgtagatag gacattccag ccttttccat
    69301 gacacgacct gaagctgggt tgagactggc ataacgtgct ctgacctttt gaaaacctgc
    69361 ttgagtaaaa caaaagtcca agacagcttt caaggcctct gtcatcatac catgtcccca
    69421 gtaagccttg cctagcacat agccgatttc acagcttaaa tcagcctcgt ctatcttaac
    69481 gatgctgata tctcctatca cttgctctgg gttttctttt agacaaatgg cccatttgta
    69541 atagttgaga ttagtatagg aagcaaccca attgcgaatc gagtttcgag tgatttcgac
    69601 atcaggatgg ggatcccagg taacataggt cagattctca gtggatgaag cccaattttg
    69661 aaacatggct tctgcatcac tctccacaaa tcttcttaaa atcaaacgtt ctgtctgtaa
    69721 tatttgcgta ccgatagatt tcatgatgct acctcacttc cttatttcta tactcgtagt
    69781 aaaaaggctc aactcagtaa cagctagaaa acgagtttgt cttctaattt cttgacgcag
    69841 ttgctgcctg gtttgaaatg cgctctagca agctttttca aacctagtca tcgttgcagg
    69901 ggtaagacga tgaaatcgaa ctcttcgagt tactgaatct gcctcatttt cttatttcta
    69961 aactcggggt tcaagatccc ccagaccttc tctcactttc ttatttcaag atgagaggct
    70021 gaaaacctcc agtggaggtt tttcttgctt tttaatttca gggcaagaag ctaaaaaggt
    70081 cccccgaacc tttttactcc caaaagtcat caaatacggt gatgggtaag tggcgtttgt
    70141 gttggccttt gtgccaccag ttttcaatgg tcgcttgagc ttctgggctg attgttttgc
    70201 cttctaggta gtcgtcaatc tctgcgtagg tgactccaag tgcgacttcg tcagctaggc
    70261 ctggtttatc ttcttctagg tctgccgttg ggattttttc ataaagggct ggctctgcgc
    70321 caagtttctg caagagctgt tttccttggc gtttattgag gcggtaaaga gggagaatat
    70381 ccgcaccgcc gtcaccaaac ttggtaaaga aacctgtgat attttccgcg gcgtggtctg
    70441 ttccaatgac cgctccgcta tgggaaccag caagggcata ctgagcaatc atacggcaac
    70501 gtgccttgat attccccttg ttgaagtctg aaacaggact acctgtcgct tcaactgcag
    70561 ctgtcatggc atcagctgat tccttgatat tcacaaccaa gctgacatct ggctggatga
    70621 aggctagggc tttttgagca tctgcttcat cagcttgcac tccgtatggc aggcggacag
    70681 cgataaattt gtagctatcg tctcccgttt cagctcgcag ttcttccata gctaattgcg
    70741 ccaaacgtcc tgccaaggtt gagtcttgtc ccccagaaat ccctagtaca aaggttttta
    70801 ggaagggatg ttttttcaga tatcttttta agaaatcaat agaacgacgg atttcttcct
    70861 gggcatcaat cactggtttg acacccagct cttggataat cgtttcttgc aaactcattc
    70921 ttcttctcct tcaccaaggg cttccttgcg catcttatca atcaagtcca tcttatcttg
    70981 ccatacatca cgcgccaaat ccactggata gtgctgcgga ttgagcacac gcttatactc
    71041 atcccacaac ttgtcaaatt ccttacgggc ataatcctga atgtcagtca aactaggcaa
    71101 gttgtaaact aatattcctt ctttgaagat atccaccaag agaggaacgg catcaaaatt
    71161 acgaaccgtc ttcttgatgt atgtataggt cggatggaac atcttaattt ctgtcatgtc
    71221 gctaatatcc acaccatcat aagtgatgta gtcaccttct gacttgcctt tttcacgact
    71281 ggtaatgcgc cacacctgct tcttacctgg cgtcgacact ttttccgcat tattagacag
    71341 cttaatcgta ttgcgcatct ggccgttttc atcttcgatt gcaacaatct tgtaaaccgc
    71401 cccaagagcc ggctggtcat aggctgtaat cagcttggta cccacacccc agacatcaat
    71461 cttggccttt tgcatcttga ggttaaggat ggtattttca tctagatcat tagaagcata
    71521 aatcttagcc tctggaaatc cagcctcgtc cagttgctga cggactttct tagaaatgta
    71581 ggcaatatcc ccagagtcaa tccgcacacc cataaagtta atctgatcac ccagctcacg
    71641 cgccacctga atggcagctg gtacaccgat gcgaagggta tcataggtat ccacaagaaa
    71701 gacacaattt ttgtgggtcg cagcgtaagc cttgaaagcc tcatagtcat tgccataaac
    71761 ctgtaccaag gcatgggcat gggttcccaa aacaggaatg tcaaagagct tacccgcacg
    71821 cacgttgctg gttccattgg cgccaccaat caccgctgcg cgtgttcccc agatggccgc
    71881 atccatttct tgagcccgac gtgtcccaaa ctccatcaag ggttcatctt cgataaccga
    71941 acgaatacga gctgccttcg tcgccaccaa ggtctggtag ttgacgatgt tcaaaagagc
    72001 cgtttcgacc aactgacatt gggctagagg tccttccacc tgcacaatcg gttcattagc
    72061 aaaaaccaaa tccccttctt gggcagaacg aacggtcaac tccaacttga aattgcgaag
    72121 gtaatccaag aacgccccat gataaccaag cgactccaaa taggctatat cactatctga
    72181 aaaacgcaag tcttcaagat agttcacaat tctttccaaa cctgcaaaaa ccgcatagcc
    72241 gttcttaaaa ggctgttggc ggaaatacac ctcaaagacc gccttcttat tgtaaatccc
    72301 ttgatcaaag taaacctgca tcatgttgat ctggtacaag tccgtgtgca atgtcaaact
    72361 atcatctgga tacatacttt tcctacttcc ttagctagaa acccatgaaa attttcaaga
    72421 actttcatgt attccaataa attagtacta ttatatcaca ttttagctgg attgagaaaa
    72481 gagtaacaag ctattctcca ctctccaatt catccatatc ttgttcaaat tttttctgag
    72541 cccattcgcc atagctctta agaccaagat tgccaataaa gacccacgga aggtaaatga
    72601 cataagtaat gacccaagca gacaggtatt taaaattcaa aggattgtgc tgataaattt
    72661 ctatgttgaa ttgataattc tgcaacatca aaagagccgt aatagccaag gttaggaaaa
    72721 aacaacccaa aatcgtaaaa tgaaaacgac tatagtaggt cactcccaga taacgggcac
    72781 gattgaaaaa gtaaaatgtc cctatgatga taacgattag cagcatatta gaattaaaaa
    72841 ggcttggtgc taatactgaa atgatataag ataggagcga caaagcgatg cagatataga
    72901 aactttcaga gcccgcttta ttgaacagtt gttcttctct ttcgtctagt aattgataat
    72961 aataaaatct atttttcatc ttcttcctcc caaaatagtt ggtctagggt tttccctaaa
    73021 catctgcaaa tggactggca gagcgagaga ctgggattgt atttccccgc ttctatcaaa
    73081 ccaatagtct ggcgcgtcac cccgacagcc tctgccagtt gaccttgtgt taaatcacgc
    73141 tctacccgag ctaattttaa ttttaaattt ttagccacct tcgtcctcct tatagtttta
    73201 atactcatct actcttaaaa aatccaaaac caacacaagc tatcagctat ttattataac
    73261 cccattaatt tgcactccag tattatcttc agccgaaaat cagtatttta ggttgtttga
    73321 aataaacttc ctagtttact cttttatttt tatttagtat tagctttagt aggatctttt
    73381 aaacgagttt ttattgctta tatttcttgt ttagtttagt tggtttcata tcactattat
    73441 ataatgcttt tggaaatgag cctagtataa gtcaaaaacg tgttgaatag tgaaagtagg
    73501 agcataccaa gatgactgat ttttttattg tattttaggt atgcaaaata atactaaatg
    73561 aaactaaaat gaatacttct tgcttttctt gagagtgaaa aagtacaata aaatgattgt
    73621 agtgattacc acaagatact gactaataga catcgtattt gaagccacaa atacaggtaa
    73681 agaataaaaa ggaagaagtt caattgcttt gataaacaaa tcattactag tattcatcat
    73741 catcgtattt aatatattag ggataaagag tagtaaagct actaaaatac caaataccaa
    73801 gccacttttc aatttgtata aataaaaaat gtaagataat agaaaataaa acaggactaa
    73861 caaaattgta ttgactacaa tagctactat aaaatctaat cctaaatcac ctggaatacc
    73921 caatttactt actatgacta gtaacacaat gccattcaaa gcataaataa tggaaactga
    73981 gatggcatat agaaaattag acaagacgta aatcatccga ttcttctgtt gattataaaa
    74041 caaacttacc gtattgtggg aaaaatctct actaataact cgattagcat gtataacagc
    74101 cattaacata ccgagcatag cataaaagtt tgaaatatgc ttaataccaa gcgatgtccc
    74161 ttgagtcttt agaataaaga atgtaagcaa tatcggcggt ataaacgaga taagcaaact
    74221 gagatatatt acgcctgatg aatataaatt tcttatattt tccttaagaa aattcaattt
    74281 atttaatttc atgattataa ccttccttta ttttgaacga tttagataaa tatctttaag
    74341 cgtctctttt ttagtttcaa aatcaactac tttaatagag ttttcgttaa aaaatttaaa
    74401 aagctcacta ctttgaatat tcccagacat agtaattctc agtccctctt cctgaacaat
    74461 atccccaaat tcttgtttgg taatgaaaat atctctatct gtagctgatg aaaaagctat
    74521 ctcaaacaag aaattatgac tatcttttcc tactttttga aatgtcaaaa gcccgttctc
    74581 caagaaaaga accctctcac aaatttcttc aatatcttct aatttatgac tcgatattaa
    74641 aattcccaca ttttcatgta aagctaaatt ttttagaacc gataaaacta tttgtgatga
    74701 ttcaatatct aaaccattag tcggttcatc taaaatcaat atatcaggtt ccgtaacgag
    74761 agttagaagc aaagctaatt tttgttttgt acccaaagaa taggtcttta cttttttatt
    74821 aatagactga gtcaaatcta actcttggat caaacttcta aatctttctt gattgtagtc
    74881 aacaccatat aaatttgaca aatattttaa attctctaaa cctgttttag ataaaaataa
    74941 ttttggttct tcgattaaat acccaacatt atcactgctt ataatattac ctgaagtcgg
    75001 ttgattattc tgaacaagaa ttttcatcaa cgtactctta ccaactccat ttctccctac
    75061 tagaccaaca atttcaccct tgttaagtgc aaaatttata tctttgagaa tgattgaatg
    75121 accataatgc ttacttacat ttataactta cattttttat tcctccatta atattcatgg
    75181 tttgctcttt gattcttatt gagtttaaaa agttgcgcct ctttttaaca acattatatc
    75241 atatatctaa cttaatgcaa tatataaatg tcattttgta aaattttatt aacaaaaaac
    75301 tctctacaac aaaataatag agagttttct gcttattaat ttttttcaaa atatctaaac
    75361 atcacttctt tgtttaattt gataggcttt gatacctaag ctccgacttt atcacttaaa
    75421 aaataaaaaa ggacagctaa tctcttgcgc atcaagggat ttcgccattc tttaatctcg
    75481 tttaagtgtt gtatatggag ctttgcatca ttttttaaaa ctaaacagct acattaagca
    75541 cgaactgtga cgctggttcc atcttcctta taaagattga tgagtccttc ttttaatgca
    75601 cgaaccatgt ctcctgattg aacgggttga ggcaccttaa tagtcaatag ttccattgga
    75661 tttggagcgc ggtcgatttt attgcctttg gcatcatgca aatcttcaat ataggtttca
    75721 aaatgacgga aacctggacc ataaaactca acttggtccc cttcgttaat gacatttcgt
    75781 tgacgaatag ttgctgtttg tgccgcatca tcataagaaa ccac
//
LOCUS       DBERPV010000007        72993 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.07, whole genome shotgun sequence.
ACCESSION   DBERPV010000007 DBERPV010000000
VERSION     DBERPV010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 72993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72993
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.07"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(207..689)
                     /gene="greA"
                     /locus_tag="ACL8C7_000621"
     CDS             complement(207..689)
                     /gene="greA"
                     /locus_tag="ACL8C7_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HGS1394875.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(760..2415)
                     /gene="mltG"
                     /locus_tag="ACL8C7_000622"
     CDS             complement(760..2415)
                     /gene="mltG"
                     /locus_tag="ACL8C7_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HGS1394876.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     IRDTSRRSRREGAKPAKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(2496..2990)
                     /locus_tag="ACL8C7_000623"
     CDS             complement(2496..2990)
                     /locus_tag="ACL8C7_000623"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1394877.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(2987..3451)
                     /locus_tag="ACL8C7_000624"
     CDS             complement(2987..3451)
                     /locus_tag="ACL8C7_000624"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1394878.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNLQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(3461..4795)
                     /gene="murC"
                     /locus_tag="ACL8C7_000625"
     CDS             complement(3461..4795)
                     /gene="murC"
                     /locus_tag="ACL8C7_000625"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HGS1394879.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSITGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(4806..5423)
                     /locus_tag="ACL8C7_000626"
     CDS             complement(4806..5423)
                     /locus_tag="ACL8C7_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HGS1394880.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTAPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(5471..8569)
                     /locus_tag="ACL8C7_000627"
     CDS             complement(5471..8569)
                     /locus_tag="ACL8C7_000627"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGS1394881.1"
                     /translation="MAKLIPGKVRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYIIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWETFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFAVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSELYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKGFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            complement(8662..9828)
                     /locus_tag="ACL8C7_000628"
     CDS             complement(8662..9828)
                     /locus_tag="ACL8C7_000628"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HGS1394882.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDSLFEIDFDQLEKDLVEEE
                     VKLYVLCNPHNPGGRVWEKEVLEKIGQLCQKHSVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVMDLFGKETKIKVMKPQGTYLIWLDFSPYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            complement(9836..10930)
                     /locus_tag="ACL8C7_000629"
     CDS             complement(9836..10930)
                     /locus_tag="ACL8C7_000629"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HGS1394883.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGHFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGSKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            complement(11088..11810)
                     /locus_tag="ACL8C7_000630"
     CDS             complement(11088..11810)
                     /locus_tag="ACL8C7_000630"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1394884.1"
                     /translation="MNFNHVYFGYDENRPVLKDITCSIFKGQKIAFVGPSGSGKSTIV
                     RLLERFYKPLSGDILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRL
                     VTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRLLSGGRSQRLQIARAYLKDAEIL
                     IFDEATANLDEDSEYAIISSLYSVLKEKTVVIIAHRLSTVKDVDCIFFLEEGKITGSG
                     THKELLENHERYARFVQEQMIE"
     gene            complement(11941..12771)
                     /locus_tag="ACL8C7_000631"
     CDS             complement(11941..12771)
                     /locus_tag="ACL8C7_000631"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1394885.1"
                     /translation="MKLKLLRVDTKVIMGSFFLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILPLSNISEKYSRRLQEEIGFLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERV
                     QNNSLKSDRVTSFETPFALLFIFATIVVMLTYGGYRVSAGYISCGNLGFVFDLPLSIT
                     "
     gene            complement(12943..14901)
                     /locus_tag="ACL8C7_000632"
     CDS             complement(12943..14901)
                     /locus_tag="ACL8C7_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS1394886.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKEVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            complement(15105..16727)
                     /locus_tag="ACL8C7_000633"
     CDS             complement(15105..16727)
                     /locus_tag="ACL8C7_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HGS1394887.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFLYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            16833..18278
                     /locus_tag="ACL8C7_000634"
     CDS             16833..18278
                     /locus_tag="ACL8C7_000634"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HGS1394888.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYIAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVKRVYGLTFDVGVFLNISLDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FRFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            complement(18324..18518)
                     /locus_tag="ACL8C7_000635"
     CDS             complement(18324..18518)
                     /locus_tag="ACL8C7_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGS1394889.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(18619..19268)
                     /locus_tag="ACL8C7_000636"
                     /pseudo
     CDS             complement(18619..19268)
                     /locus_tag="ACL8C7_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614493.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            complement(19252..19764)
                     /locus_tag="ACL8C7_000637"
     CDS             complement(19252..19764)
                     /locus_tag="ACL8C7_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiX/YebB-like N1pC/P60 family cysteine
                     hydrolase"
                     /protein_id="HGS1394890.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            complement(19850..20785)
                     /locus_tag="ACL8C7_000638"
     CDS             complement(19850..20785)
                     /locus_tag="ACL8C7_000638"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HGS1394891.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGVNMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            complement(20856..21155)
                     /locus_tag="ACL8C7_000639"
     CDS             complement(20856..21155)
                     /locus_tag="ACL8C7_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HGS1394892.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            complement(21145..21894)
                     /locus_tag="ACL8C7_000640"
     CDS             complement(21145..21894)
                     /locus_tag="ACL8C7_000640"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HGS1394893.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            complement(21948..22307)
                     /locus_tag="ACL8C7_000641"
     CDS             complement(21948..22307)
                     /locus_tag="ACL8C7_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HGS1394894.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            complement(22309..23709)
                     /locus_tag="ACL8C7_000642"
     CDS             complement(22309..23709)
                     /locus_tag="ACL8C7_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HGS1394895.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFAALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGQSIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTIFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            complement(24004..24243)
                     /gene="rpsR"
                     /locus_tag="ACL8C7_000643"
     CDS             complement(24004..24243)
                     /gene="rpsR"
                     /locus_tag="ACL8C7_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HGS1394896.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            complement(24275..24745)
                     /gene="ssbA"
                     /locus_tag="ACL8C7_000644"
     CDS             complement(24275..24745)
                     /gene="ssbA"
                     /locus_tag="ACL8C7_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HGS1394897.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            complement(24757..25047)
                     /gene="rpsF"
                     /locus_tag="ACL8C7_000645"
     CDS             complement(24757..25047)
                     /gene="rpsF"
                     /locus_tag="ACL8C7_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HGS1394898.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            complement(25200..26546)
                     /gene="asnS"
                     /locus_tag="ACL8C7_000646"
     CDS             complement(25200..26546)
                     /gene="asnS"
                     /locus_tag="ACL8C7_000646"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HGS1394899.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALEILERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            complement(26562..26927)
                     /locus_tag="ACL8C7_000647"
     CDS             complement(26562..26927)
                     /locus_tag="ACL8C7_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGS1394900.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSERLIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            complement(26920..28107)
                     /locus_tag="ACL8C7_000648"
     CDS             complement(26920..28107)
                     /locus_tag="ACL8C7_000648"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGS1394901.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAESRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKEAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            complement(28104..28592)
                     /locus_tag="ACL8C7_000649"
     CDS             complement(28104..28592)
                     /locus_tag="ACL8C7_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HGS1394902.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQVDQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            28913..29461
                     /locus_tag="ACL8C7_000650"
     CDS             28913..29461
                     /locus_tag="ACL8C7_000650"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HGS1394903.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            complement(29739..30467)
                     /gene="yaaA"
                     /locus_tag="ACL8C7_000651"
     CDS             complement(29739..30467)
                     /gene="yaaA"
                     /locus_tag="ACL8C7_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HGS1394904.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQAVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSLMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(30546..30710)
                     /locus_tag="ACL8C7_000652"
     CDS             complement(30546..30710)
                     /locus_tag="ACL8C7_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HGS1394905.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            complement(30889..32484)
                     /locus_tag="ACL8C7_000653"
     CDS             complement(30889..32484)
                     /locus_tag="ACL8C7_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394906.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDSKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            complement(32496..32906)
                     /locus_tag="ACL8C7_000654"
     CDS             complement(32496..32906)
                     /locus_tag="ACL8C7_000654"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGS1394907.1"
                     /translation="MEKKIVKDILFLSQVSKPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            complement(33022..33813)
                     /gene="yghU"
                     /locus_tag="ACL8C7_000655"
     CDS             complement(33022..33813)
                     /gene="yghU"
                     /locus_tag="ACL8C7_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HGS1394908.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            complement(33826..36522)
                     /locus_tag="ACL8C7_000656"
     CDS             complement(33826..36522)
                     /locus_tag="ACL8C7_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGS1394909.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LLEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            36826..38010
                     /gene="mntE"
                     /locus_tag="ACL8C7_000657"
     CDS             36826..38010
                     /gene="mntE"
                     /locus_tag="ACL8C7_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HGS1394910.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEDRF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            complement(38153..40024)
                     /locus_tag="ACL8C7_000658"
     CDS             complement(38153..40024)
                     /locus_tag="ACL8C7_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGS1394911.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQDVSFAYENKPILQN
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLESTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(40021..41220)
                     /locus_tag="ACL8C7_000659"
     CDS             complement(40021..41220)
                     /locus_tag="ACL8C7_000659"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HGS1394912.1"
                     /translation="MRLTQMPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIH
                     DVDIATSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSA
                     VSFVRSLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDA
                     LRIMRGFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLA
                     SMIESQAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKS
                     WKTSRQFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAI
                     TEKYQSLTIHDKKDIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIH
                     AYLREKK"
     gene            complement(41217..41984)
                     /gene="dapB"
                     /locus_tag="ACL8C7_000660"
     CDS             complement(41217..41984)
                     /gene="dapB"
                     /locus_tag="ACL8C7_000660"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HGS1394913.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDSDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            complement(42250..43098)
                     /locus_tag="ACL8C7_000661"
     CDS             complement(42250..43098)
                     /locus_tag="ACL8C7_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGS1394914.1"
                     /translation="MKLAVFTDSSAYLSAEILQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYPKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            complement(43100..43474)
                     /locus_tag="ACL8C7_000662"
     CDS             complement(43100..43474)
                     /locus_tag="ACL8C7_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HGS1394915.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            complement(43548..44900)
                     /gene="glmM"
                     /locus_tag="ACL8C7_000663"
     CDS             complement(43548..44900)
                     /gene="glmM"
                     /locus_tag="ACL8C7_000663"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HGS1394916.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            complement(44924..45703)
                     /locus_tag="ACL8C7_000664"
     CDS             complement(44924..45703)
                     /locus_tag="ACL8C7_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HGS1394917.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEIPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            complement(45690..46547)
                     /gene="cdaA"
                     /locus_tag="ACL8C7_000665"
     CDS             complement(45690..46547)
                     /gene="cdaA"
                     /locus_tag="ACL8C7_000665"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HGS1394918.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            46683..47651
                     /locus_tag="ACL8C7_000666"
     CDS             46683..47651
                     /locus_tag="ACL8C7_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGS1394919.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            complement(47685..48596)
                     /gene="whiA"
                     /locus_tag="ACL8C7_000667"
     CDS             complement(47685..48596)
                     /gene="whiA"
                     /locus_tag="ACL8C7_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HGS1394920.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHLYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(48593..49570)
                     /locus_tag="ACL8C7_000668"
     CDS             complement(48593..49570)
                     /locus_tag="ACL8C7_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HGS1394921.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDDGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            complement(49567..50457)
                     /gene="rapZ"
                     /locus_tag="ACL8C7_000669"
     CDS             complement(49567..50457)
                     /gene="rapZ"
                     /locus_tag="ACL8C7_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HGS1394922.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            complement(50509..50889)
                     /locus_tag="ACL8C7_000670"
     CDS             complement(50509..50889)
                     /locus_tag="ACL8C7_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HGS1394923.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            complement(50900..51487)
                     /gene="yihA"
                     /locus_tag="ACL8C7_000671"
     CDS             complement(50900..51487)
                     /gene="yihA"
                     /locus_tag="ACL8C7_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HGS1394924.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            complement(51496..52728)
                     /gene="clpX"
                     /locus_tag="ACL8C7_000672"
     CDS             complement(51496..52728)
                     /gene="clpX"
                     /locus_tag="ACL8C7_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HGS1394925.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            complement(52760..52930)
                     /locus_tag="ACL8C7_000673"
     CDS             complement(52760..52930)
                     /locus_tag="ACL8C7_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394926.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            complement(52930..53436)
                     /locus_tag="ACL8C7_000674"
     CDS             complement(52930..53436)
                     /locus_tag="ACL8C7_000674"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HGS1394927.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            complement(53566..54084)
                     /locus_tag="ACL8C7_000675"
     CDS             complement(53566..54084)
                     /locus_tag="ACL8C7_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HGS1394928.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            complement(54580..56085)
                     /gene="lytC"
                     /locus_tag="ACL8C7_000676"
     CDS             complement(54580..56085)
                     /gene="lytC"
                     /locus_tag="ACL8C7_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HGS1394929.1"
                     /translation="MSVTFFIGEERLKIKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAYWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMIQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTGTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            complement(56123..56881)
                     /gene="tpiA"
                     /locus_tag="ACL8C7_000677"
     CDS             complement(56123..56881)
                     /gene="tpiA"
                     /locus_tag="ACL8C7_000677"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HGS1394930.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            complement(56980..57657)
                     /locus_tag="ACL8C7_000678"
     CDS             complement(56980..57657)
                     /locus_tag="ACL8C7_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGS1394931.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELFFDASLALERL
                     DDLFGAVRSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            complement(57666..58610)
                     /gene="metA"
                     /locus_tag="ACL8C7_000679"
     CDS             complement(57666..58610)
                     /gene="metA"
                     /locus_tag="ACL8C7_000679"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008899 - homoserine O-succinyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0019281 - L-methionine biosynthetic process
                     from homoserine via O-succinyl-L-homoserine and
                     cystathionine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HGS1394932.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            complement(58792..59304)
                     /locus_tag="ACL8C7_000680"
     CDS             complement(58792..59304)
                     /locus_tag="ACL8C7_000680"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HGS1394933.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            complement(59391..60149)
                     /locus_tag="ACL8C7_000681"
     CDS             complement(59391..60149)
                     /locus_tag="ACL8C7_000681"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGS1394934.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            complement(60650..61780)
                     /locus_tag="ACL8C7_000682"
     CDS             complement(60650..61780)
                     /locus_tag="ACL8C7_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1394935.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(62064..62149)
                     /locus_tag="ACL8C7_000683"
     tRNA            complement(62064..62149)
                     /locus_tag="ACL8C7_000683"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(62113..62115),aa:Leu,seq:aag)
     gene            complement(62231..62806)
                     /locus_tag="ACL8C7_000684"
     CDS             complement(62231..62806)
                     /locus_tag="ACL8C7_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGS1394936.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            complement(62806..63594)
                     /gene="codY"
                     /locus_tag="ACL8C7_000685"
     CDS             complement(62806..63594)
                     /gene="codY"
                     /locus_tag="ACL8C7_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HGS1394937.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            complement(63859..65433)
                     /locus_tag="ACL8C7_000686"
     CDS             complement(63859..65433)
                     /locus_tag="ACL8C7_000686"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGS1394938.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQNIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            complement(65632..66858)
                     /locus_tag="ACL8C7_000687"
     CDS             complement(65632..66858)
                     /locus_tag="ACL8C7_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HGS1394939.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPRVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSASGKEKTDSLTQGMTANQALKS
                     NRFYILWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            67052..68368
                     /locus_tag="ACL8C7_000688"
     CDS             67052..68368
                     /locus_tag="ACL8C7_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HGS1394940.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVNIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            68467..69810
                     /gene="murT"
                     /locus_tag="ACL8C7_000689"
     CDS             68467..69810
                     /gene="murT"
                     /locus_tag="ACL8C7_000689"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016881 - acid-amino acid ligase activity
                     [Evidence IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit MurT"
                     /protein_id="HGS1394941.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEMVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            69810..70592
                     /gene="gatD"
                     /locus_tag="ACL8C7_000690"
     CDS             69810..70592
                     /gene="gatD"
                     /locus_tag="ACL8C7_000690"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit GatD"
                     /protein_id="HGS1394942.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            70718..71800
                     /locus_tag="ACL8C7_000691"
     CDS             70718..71800
                     /locus_tag="ACL8C7_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGS1394943.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTIFETAEFENLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     IIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            71748..71996
                     /locus_tag="ACL8C7_000692"
     CDS             71748..71996
                     /locus_tag="ACL8C7_000692"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1394944.1"
                     /translation="MASTSLQAPAKICFILIKLYSPYAFLSKYLGAILLSFFCYYAKE
                     IGCNNLTLSVWNDNEGALRFYQRQGMKPQETTMEMIID"
     gene            complement(72124..72993)
                     /locus_tag="ACL8C7_000693"
                     /pseudo
     CDS             complement(72124..72993)
                     /locus_tag="ACL8C7_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT        21173 a        16514 c        13632 g        21674 t
ORIGIN      
        1 agctcaaaac atagttttga ggttgtagat gaaactgacg aagttagctc aaaacactgt
       61 tttgaggttg taaatgaaac tgacaaagtc agtaaccata catacggcaa ggcgacgctg
      121 acgtggtttg aagagatttt cgaagaatag caaaatggaa aaaggagtga gtgaagcaca
      181 tcgcctcccc actccttttt ctgtttttag gctgtttttt caaccttcaa gatttttaca
      241 tcatagctac caacaggcgt ttcaatggtt gctgtgtcac ctgttttctt gccaatcaag
      301 gcctgcccaa ttgggctttc atttgaaacc ttacctgcaa aggcatccgc accagctgaa
      361 cctacgataa tataaacttc ttcttcgtcc tcaccaattt cttggatggt gactgtttta
      421 ccaatcgcta cttcgtcctg ggcaactgcg tcgctattga cgatttcagc atagcggatt
      481 tttgtttcta agctagagat ttgtccttcg acaaaggctt gttcatcctt agctgcttcg
      541 tactcactgt tttctgaaag atcaccgtat gaacgggcaa tcttaatgcg ttctaccact
      601 tctggtcgac gaaccaattt caattcttct aattcttttt caagtttctc cttttcctca
      661 agggtcatag gatatgtttt ttctgccatt tttctcaact ttcttctgat aatattttct
      721 aaagaaaatt atgtgaagta tcacataatt ttagtttgtt tagtttaatt tgctgttgac
      781 atgttcagcg acattgcggt cgtggtcttc ttgattgtta gcatagtaga ccttgccttc
      841 tgtgacatct gctacaaagt agaggttatc gctcttagtt tgattgatgc ttgactcaat
      901 cgcatccaga cttggactat cgactggacc aggcatgaga cctacatttt tataaacatt
      961 ataaggtgaa tcaatgttgg tatcaatcgc aacatcctca gctagactga tattttgccc
     1021 cagttttcct tgggcataca agattgcaat attactttga agtggcatat cacgattcaa
     1081 acgattgtag aatacacctg caatgagctt acgatcttct gtcttggcac cttctttttc
     1141 gaccaaggaa gcaatggtca acaactcatt gacagtcaag tttttagatt tgatagtact
     1201 atagtaagga gataggttct tatccatagc agctaacatc tcatcaatca agctctcaat
     1261 agttgtgctt tccttgatag agtatgtagc tgggaaaagg tatccttcca aacgataacg
     1321 cgcaccgctg tcttttacag gcaaactttc cagtaaagta ggatatttcg ctactgcttg
     1381 actgataaac gtctcatctt gaactttagc caagaaagcc tccgctgtca aagactcttt
     1441 gaagtcacct tgcaattgac ccacagtttg agcaatctga tccaaggtat aaccttctgg
     1501 aattgtcaaa gtcgcaagta caggttcttg cggttcatct gttccacctt tttgcaactc
     1561 tttgagtaag tcttctgtac tcatactctt ttgcaaattg tagtaacctg ctttcaagtc
     1621 ggtataattt ttatacttgg cataaaaact aaaaatcaga ccatgcttta ccaaaccagc
     1681 tttttcaagc gtcgtaccga tttcttgaac gtttgaacct tctggaattc caaccgtcac
     1741 atatttctta gaattagcat cgataggtaa taaggaatct agcacgtact ggtaaccaaa
     1801 gtaaccacct gctgagagca aggcaaggaa tacaaggaat gaaatcacaa aagctttcac
     1861 atgtgacttc ttctctttct taggcttagc gggttttgct ccttctctac ggctacgacg
     1921 tgatgtatct ctgatgatat ccactgtttc tgtagcaggc gtaggtgttt ctggacctgc
     1981 ttgttctgct tttttctctg ccgtcgtata ggaaacagct acccttgttg gggtttcatt
     2041 gtattctctt tcaagtttct taggtctaac aggacctgga cctggtcttg atccactttc
     2101 ttccgctgga gaagaaggta catcttgact tggatgactt ggaacaccag gagtttctct
     2161 ttgaatctca tctgctggag aagctggtac accttgactt gggtgagtag gcacggtagg
     2221 agcttttctc ataatctcct ctaccgttga caaggaatca gccatgagtt cttcagctga
     2281 aggttcattt gcaggagtgc gaactactgc ctcatcttct ttcagaactt catcatagcc
     2341 ttttactttt tctaaatctc tcagaatctg ctctttaaag cttaatttct cttcttctct
     2401 tgacttttca ctcaaaagtt tttcctcctt gttgataatc cataatatta tatcttaaaa
     2461 gtccaaaaaa agcaatctat gatacttttc ctaacttatt ttttcatttc ccagaccata
     2521 tcataccatg tttcccctgc aaaggttgac tgggactggc cttcgttgac aaatccatgt
     2581 ttttcataat aggcgatgag atagtcatga caggttagat taatgccatc tctctcatct
     2641 tcaagagcaa cttctttcaa ggctgtcagc aatttctgac ccagtccgag tccctgtgcc
     2701 tccttggcaa tagacagaca ggtcacagag atataaccac caggctcatg actatagtct
     2761 tttatttctt ctgtaaaaga ctggtcttgc agatggcggt gcaggccaac tggtccttcg
     2821 atataaccca tgattcttcc ttctttttca gcaaccagaa aagaggtctg aatttctctc
     2881 aaatgtgctt caaagacaga aggaggaatg gcttcttcga ccgaaaaatt ttcaaattca
     2941 agttcaacaa tccgatccaa atcttctaat cttgcttgtc tgattttcat tgttcctcca
     3001 gataaaaggg attaaaccaa atcatactat agccctggct agttgcatag agcaaagttg
     3061 cttcttcatc aacaaaaccg ttcatttcaa aataggaaag cagctcatca ggactctcca
     3121 aacgaatccc tttgtaatcc agctcaactg ccacctcttt caaggctgca agaagaagtg
     3181 ttcccaggcc ctgtctctga tggtcagact cgatgactaa agaatgtact tttagacatt
     3241 gcagattgtc tgactgggga cttgataaaa tatagcctaa aagttgattt tcatccctag
     3301 ctagaagaaa ggtatccgca cacttacgga tactttcttc taaaatatgg gaaagttgct
     3361 gcttttcagc tggaaaagac gaggtctgaa gtgcccctat ctcaggcaaa tcagacttgc
     3421 ttgcctgaat gatcttaatt ggaatttcca tgggaacatc ctattgaaca ttgcttgtca
     3481 agttagacaa gagacgctca aatgagtatt cataggtttg gatgtctcct gctcccataa
     3541 agacgtaaac agcattgtca tggtctagga gtggagaaac attttcaaca gtaatcactt
     3601 ggtgtttttt gttgattttg ttggctaggt cttctacctt aacgtcacca tgatctactt
     3661 cacgagccga gccataaatt tgcgctagat aaacagcatc tgcttggttt aaagcatggg
     3721 caaagtcgtc caacaaggca atggttcttg taaaggtatg cggttgaaag actgctacaa
     3781 tttccttgct tgggtatttc tgacgagccg catccaaggt cgcaataatt tctgttggat
     3841 ggtgggcaaa gtcatcgata atcactgtat cattgacaat tttctcagtg aaacgacgtt
     3901 taacaccggc aaatgttttc aagtgctcac gcaccaagtt caaatcaaat cctgctgtgt
     3961 aaagaagacc aataacggct gtcgcattca tgatattgtg acgaccaaag gttggaatgt
     4021 ggaattgccc caagttttgt ccacggaaat gaacggtgaa ggttgaacca gttattgaac
     4081 gaagaagatc actagctaca aagtcattgc cttcagcttc aaaaccataa taataaattg
     4141 gtgcatcaga cgtaatctta cgcaattcag catcttcacc atagacaaaa agacccttgg
     4201 tgatttgttt ggcatagtcg ttaaaggcat taaaaacatc ctcgagactt gtgaaataat
     4261 ctggatggtc aaagtcaatg ttggtgataa tagagtattc tgggtggtaa ggcatgaagt
     4321 gacgctcata ttcgtcagat tcaaagacaa aatatttggc attggccgaa ccacgacctg
     4381 tcccatctcc aatcaagaag ctggtatctg taatgtgaga caagacatga gacaacatac
     4441 ctgtcgttga agtttttcca tgtgctcctg ctactcccat gctaacaaag tcacgcataa
     4501 agctacctag aaactcatgg taacgtttgt agctgatacc attttggtcc gcataggcaa
     4561 tttcgacgtt gttatctgga cgaaaggcat ttccagcgat aatttccata tcaccgtcta
     4621 gatttttttc atcaaaagga agaatggtaa ttcctgcctg ctcaagaccg cgttgggtaa
     4681 agtagtactt ttcaacatct gatccctgaa ccttgtgccc catctggtgc aacatcaagg
     4741 ccaaggcact catccctgat cccttaattc cgataaaatg atatgtcttt gacatgtttt
     4801 ctcccctatt ctgtcattct ggtcagattc aactcttggg caacccgacg ttcttgttct
     4861 gtttgtttac tttttttatt gtagatttgg ctcttcttta gaaaatcata attgtttttc
     4921 tttggagcag gtgctgacac ttcttcattc ttggtaggga tagaatgaac ttcttccgcc
     4981 aagatataat gagactgggt caatttttgg ctatatttga caaattcacc aggattttcc
     5041 ttttggaaag gagctgtcgg ttgattgccc tgtctaacta gactgggctg agaatgacgt
     5101 ctcgcaaggc tgaaatcctg agttaggtag ttagcagagc gtttcttttt caagtccgca
     5161 cgcgcttctt cacgcgccac ctccgcatag ctctttcctt cttttttaac ccctaaagga
     5221 gcctttttag gtttttcgac ttgcttttca atcggtttta ctggtttttc ttcagcaata
     5281 ggagcccatt ctaaataatt tttatctcga tactcaccct tgatattact gatcagatca
     5341 gactcatcat agagattcat gactggcatt tcagtcaaca tgacctcgtc atctgacacc
     5401 aatggaaatc gttcttgttt cattttctat ttcctttcaa cacttcatta tagcgtattg
     5461 tcttgatttt tcaagtgctg gcttcagaaa ttcccaaaat ttctctaatt tctgctaggg
     5521 tcagactacc acgtgactct gtgccgtcca atacttgtga caccagatgt ttcttttgtt
     5581 cttggagttc ctgaattttt tcttcaatgg ttcccttggt caccaagcga tagacctcaa
     5641 ccgtttcttc ctgacccatc cgatgggcac ggccaatggc ttgcgcttcc accgcaggat
     5701 tccaccaaag gtcaaccaag atcactgtat ctgcacctgt caggttcaga ccgaccccac
     5761 cagccttgag ggaaatcaga aaggcatctc tttctccttg gttaaaggcc ttggtcatgt
     5821 cttgtctttc cttggctggg gttgaacccg taattttaaa ggaagtcagg cccaagtctg
     5881 gcagttcttg ttcaattttt tccaacattc ccttgaactg agagaaaatc aagacacggt
     5941 gtccgccgtc tgccacctgt accagtaggt ctcggagact atctagtttg ccgctggctc
     6001 cctgataatc ttccataaac agggcaggag tgtcacatat ttgacgcaag cgcatcaaac
     6061 cagataaaat ttccacacga cttcgctgaa attcctgttc tgacacttga gccagatggt
     6121 ctcgcatctg ttgtaactgg gcaaggtaaa tagccttttg ctggtcttcc agttcatttt
     6181 tataaaccac ctcaatcaag tctggcaatt cagtcagaac ttcttctttc ttgcgtcgca
     6241 tcacgaaagg cttgataaac tgagccactc gctctgctgg caatttcata aatcctttct
     6301 tgcttggcaa aagtccaggc atgacgattt gaaaaataga ccacaactca cccagatggt
     6361 tttcaatcgg agttcctgac aaggcaaaga ccgacggcac cacaaattgt ctcaaggtct
     6421 gggcaatctt ggtctgggca tttttcatga cctgagcttc atctaagaaa aggaagtcaa
     6481 aggccatccc ctgataaagc tcactgtcct gacggaaggt ggcatagcta gtcacataga
     6541 tttgatggct ctcggcaaga atctcctcac gacttgcttt caaaccatga acaacagcca
     6601 catccaactg tggagcaaat ttctgaaact catctgccca gttgtaaatc aaacccgacg
     6661 gagcgagaat caaaacccga ctttcttttg tcacttgact agtcaaaaaa gcaatagtct
     6721 gaagggtttt cccaagtccc atatcatcag ccaaaatccc accaaaacca taatgatgga
     6781 gcatctgcaa ccagccaatt cccttttcct gataatctcg caagtcagcc ttgacctgag
     6841 ttgcttgcaa aggaaagtcc tctggatgcg tcaaatcctg ggccagattc tggaattctt
     6901 gtgaaaaaga aacacggtct cgcccttcaa agagatgagc taaactgtag gccaaggatt
     6961 tccgagcctg caaggtccca tcttttaatt caaattgccc cagttcctgt agattttggc
     7021 gaattttctt ggtttcttca tcgaaaaagt aaacttgatt agacgaatca atataaaaat
     7081 cctgattggc aaccaaggcc tgcatggctt ggtcgatttc ctcctgggca atattttgaa
     7141 aatcaaactg gatttccaag agacctccct tggaggcaat ctgcacctga ggactcgcta
     7201 ggctataaag ctcttctagt ttatctgata ggtcaacatg cccgagtttt tcaaagactg
     7261 gaatgatatc atgaaaaaaa tgatagacag actccgcttt taaggcctga cgccaagatt
     7321 gaaaatcggc ttcaaagccc gcagccaaac agacttggaa aattctttct tctaagtctg
     7381 cgtcacttga aaagggtaat tcttctagct cttgtcggct agatacctgt ctatttccat
     7441 aatcaaactg aatttctaaa cgaatccgat tatcttcttc cctgtcaaag taaaaagagg
     7501 gcgcaaaagt tttgatttgt agacgttctg gagctgaaac ggtgcccatc tggataaaaa
     7561 gagtcagaca ggaggccaat ttgtctcgat cactgctatc aaattgcagg tatttctttc
     7621 cttgttgacc cacaggtaac gctttaattt ccttgagaag acgcatctgc tggtctgtta
     7681 aaaaataaac ctgaccttta tggaaaagta ctgctccctg ataaaagaca ttgaccctag
     7741 gactctcact gatttccatt tcaaaataat ccgagtattc tgttactgca aaggcaaata
     7801 gattggcatc agcatgcata tcctgaaaaa gcagggtttg gtagctatcc acttgatggt
     7861 caaattgaaa atggggcaag gccatcagta aattcacacc ctgctcaaaa aaggtcagag
     7921 ggaaaaagag gtgccgacct tggttttgga aaaagaggtc tggaaccagc ccttcctccg
     7981 ttagtccgtg caagaaagtc aaaagttctt ggctggcatc atcaaaggtt tcccaagaaa
     8041 gagactcctc ataaatcttg ccaatcatat acgactttct ctgctcgaca atccttaaaa
     8101 aaagtggaat atcccgaatg atatagtatt tttggctatt gatttggccg attctcagag
     8161 tccacaagat atgattggtt cctgcttcca cctgacccac agctgataac tcataggcgc
     8221 attctgattt tggagataaa attcgatcca aaaacttgcc acccaaggtc accttggttt
     8281 caacggcctc tttttcttca tgaccttctt ccagactcca caagatttcc tgaccacgct
     8341 catcattttt cagaaaatgc tctagcgctg ccaaatgcac acagtaaccc ctcttttgaa
     8401 aaaaatcaca ggcacaaaaa accaaatcat cctctaaact atagcgcagt tcttcttctg
     8461 caacgcgagc gtagagccga ttgttctttt ccttgatgat atcaacctta ccagtttcat
     8521 aaagggcaac accttcgata cgaactttcc ccggaatcaa tttagccata ttttcacctt
     8581 taccttatct ttttattata ccatattttc gcctatgaaa atagccttct aggaagactt
     8641 ttctcctaga aggctggatt tttaacgttt ggcaaaagta gccacaatcc gctgacagac
     8701 ttcttgcaac agagatttgg gcatagctat attgatgcgg gcatggagac ttccttcctc
     8761 tccaaaatcc aaaccacggt tgaggataac cttggcttca tttctcaaca actcttgcaa
     8821 tgtttcatca gtcaggtcat aaggtgaaaa gtcaagccaa atcaagtagg taccttgcgg
     8881 tttcatgacc ttgattttag tctcttttcc aaatagatcc atcacataat tgatgtggtc
     8941 ttcaaagact tgcttgagtt cctctagcca atctttaccg tatcgatagg cagcttctgt
     9001 cgccaaataa cccaagcctg aaatttcatg ctgattattg gccaacaggc gtttctggaa
     9061 agccagtctc aacttaggat tttcaatgac tgcataggaa ttttttgttc cagcaatatt
     9121 aaatgtttta gtggcactac tcaagacgat agcaaaattt ttgaaggcag gattgatggt
     9181 attgaaagac tggtgtttgt gaccaaagag ggtcaaatct tggtgaatct catccgaaac
     9241 taacaaaaca ctgtgttttt ggcagagttg gccaatcttc tccaacactt ctttttccca
     9301 aacacgtcca ccaggattgt gagggttgca aagaacatag agtttaacct cctcttccac
     9361 caaatccttt tcaagttggt caaagtcaat ctcaaacaga ctatcctttt ccactaagga
     9421 attagtaatc aatctacgat tattcaactt gacactgcga gcaaagggtg ggtagacagg
     9481 cgtgttaatt aaaaccgcct cgccttcttt tgtaaaggtt tgaatagctg ttgagatggc
     9541 tggtaccaca ccctcgataa agacaagagc ctctttgtca aagttataac cgtattgtgt
     9601 agcttcccac ttttgaactt ccttaattaa gtcttcactg gcataggtat aaccataaac
     9661 cagttggtct gcgtaagttt gcacggcttg gcggatttca ggcaagacca caaagtccat
     9721 atccgctatc caagctggta gaacttcact atccgtttct gtttctttcc atttataggt
     9781 atggtgccct aaacggttgg gcaggcttgt aaaatcatat tttcccatct ttgtcttatc
     9841 cttctaaggc ttggcgcaaa tctgcaatca aatctctagc atcctcaatc ccaatagaca
     9901 aacgcaagag gtcatctgtc aaaccataag aatggcgtac ttctgctgga atatcagcat
     9961 gagtttgagt cgttggataa gtaataagac tttccactcc gcccaaactt tccgcaaaag
    10021 agaagacctt gagactgttc aaaatatgag gaatgcgtgt ttcatcggct actttaaagg
    10081 aaatcatgcc tccacgacca gtgtagagaa cttccttaac tgctggagaa tccttcaaaa
    10141 aggcaaccac ttcttgggcg ttagctgttg agcgctccat acgaagagac aaggtcttga
    10201 gaccacgaag caactggtag ctgtcaaatg gagacaagac tgcccctgtt gtattaagat
    10261 tgtaaaaaag cttctcgtat agctctaaac tattggtcac aaccactcca gccaagacat
    10321 cattgtggcc tgctagatac ttggttgctg aatggagaac gatatctgct ccatcttcaa
    10381 tcggacgttg gtagataggg ctatagaagg tattgtccac caccactttg gaacccttag
    10441 catgagccaa ttttgctagt ttttcgatat caaattccaa catcaaggga ttggttgggg
    10501 tttcgatata gagaacatcc acatcctttt ctaactcggc aatcaactct tcttctgtat
    10561 tggcataggt aaaatggaaa tgaccttcct gctccacttg gttaaaccag cgaaaagaac
    10621 caccgtaaag atcacgcact gccaagacct tacttcctac tggaaagacg ctaaaggcca
    10681 gtacaatagc tgacatccct gagctagtcg ctagggcata gtctgctgac tcaatagccg
    10741 ccaagacttc ctcagcctta ctacgagttg gatttttagt gcgcgtatag tcaaacccag
    10801 tagatcgacc aaactctgga tgctgatagg tcgttgaaaa atgaagtggt gtcaccaaag
    10861 cacctgttgc ctcatcagac ttgatccctg cttgtgctaa aattgtgtta atgtgtaatt
    10921 ccttgctcat acaattcctc caaatctata gtaactattg taccacttat tttcatcaac
    10981 tcattttctt cttttcaaga gctagttata gtttcaaact atataaaaag ggagtttttc
    11041 ctgctccctt taatagacta taaaatggtg aatctcaaaa gacaccttca ctctatcatt
    11101 tgctcctgca caaaacgagc ataacgctca tgattttcca gtagttcctt atgagttcct
    11161 gagccagtga ttttcccctc ctctaagaag aaaatacaat ccacatcttt taccgttgac
    11221 aaacgatgcg ctataatcac aaccgtcttc tcctttagta cagaatagag gctactgata
    11281 atcgcatact cagaatcctc atcaagatta gcagtggctt catcaaatat aagaatttca
    11341 gcatctttta agtaggctct agctatttga agtctttggc ttcgcccccc tgacaagagt
    11401 cgtccgcgtt caccaacttc agtatctagt ccctctttca tggagcgaat ctcatcacct
    11461 agtgatacta agtctagcac tttcatcaat tcatcatcag ttactaagcg attcaaaccg
    11521 agacaaagat tgtcacgaat actgccagat aagactgcat tattttgtga aacccaagcg
    11581 attttacttc tccattcttt taagttaaaa tcatatatac ttgattgctc cattagaata
    11641 tctcctgaaa gcggtttata aaaccgctct aacaaacgca caatcgttga ttttcctgat
    11701 ccagatggcc caacaaaagc aattttttgc cccttgaaaa ttgaacaagt aatatccttt
    11761 aagacaggtc gattttcatc ataaccaaaa tagacatggt taaaattcaa cccttgtcct
    11821 gataccgatt ttcctccctc aaatttttct ttaggaactg caagcaagtt ctccagtgca
    11881 actgaagatc ccttgctact agaataaata gttacaaaat tagctatatt actaatagga
    11941 ttaagtaatt gaaagaggta aatcaaaaac gaaaccaagg ttcccacagg atatatatcc
    12001 tgcgctgacc cgataacccc cataggttag catcacaact atagtcgcaa agataaataa
    12061 gagagcaaac ggggtctcaa aagaagtaac cctatctgat ttcagtgaat tgttttgtac
    12121 cctttcaata caattatcca aaacatcctg tacacttttc tctgcttggt tagtcttaat
    12181 taattcatgt tcttgaatct tttcagtcaa ttgccctgtt aaaaatccga tttcctcctg
    12241 taaacgacga ctatactttt cactgatatt ggaaaggggc aagataataa acatcataca
    12301 aggaagagtg atgaataaaa gtagagaaag attccaatca agactaaata agactacaat
    12361 ggaaccaagt accataacta aactcagaat aatatttggg aaagtcgtaa ttaaaaactc
    12421 acgaatgaca ctcgtgtcat tgacaatggc agaagtcaac tccccacttt ggctcttatc
    12481 aaagaaggat ttctctgcat aaatcaaccc ctctatcact tttttcctga tttttgctat
    12541 ctttttttca cccgattgac taaacagata gtaaccaata gaagaaaaca aggcttgacc
    12601 aataaaaatc aaaaacgatt gaaatacttt ggaacctata ttttcaatag aactcccatc
    12661 tattaaaccc tttaagataa ggggaagcaa caaagcaagt agactagaca gaacaaggaa
    12721 gaaactcccc ataatcacct tagtatctac tcttaataat tttaatttca taaatactcc
    12781 ttataatatt tcaacggata aagtcgggaa taactcaatt tgaggataaa atctaataaa
    12841 tcttcctata acaaaacgca taacatctag gattttatat acctgatatt atgcgttttt
    12901 aagcacaaag acttcttaca caaacttatc tacaattaga ttttatttga catgttttgc
    12961 caattcttct tgggcttttt tattggattc ttctttttct ttcaaccatt tttctctggc
    13021 ttttgcatat tcgtctgttg tgacaatctt atcttgtact ttgaggtatt tatatgattc
    13081 aacccctttt gtaccggtta aaccataggc agcagcaaat ggtacggttc ttctcaatga
    13141 tggtgttccc ccacgcgaaa cacttggaag aactaaagaa ctatcaatca accaagcttg
    13201 aatatcagca tatttctcat aacgtttggc tggatcttgc tctttattag cttcttccaa
    13261 catttgagta tagacatcca gtccaacttc cttagccttg tcattggctt ctccaggctc
    13321 tagtccaaga ttttgtagaa ctcctccact attagtatta aaaatatcga gataggttga
    13381 cgggtcttga taatcaggtc cccaaccgcc atgatataaa tcatagtctt tctgagcagc
    13441 tgtttgagca aagtagcctg aactgtcaaa ctcatctgat gttaattgct gaatgtcaat
    13501 cactacatta tcagaaccta aaacagattc aattgattgt ttgatagaac taactccttg
    13561 tatgcctact ttatctgtta cttccacagt cttatccaag tggattggga attgaacacc
    13621 ctttgcttcg agttctttct tagcttccgc aaacttagcc ttggctttct caggattgta
    13681 gtaagggtct tgaccatccg caaagttgat accttgccat tccttaccat agttgaccat
    13741 cttagaggct acaacttcac caaagtcttt tcccttgata ctgacaaagt ttggaggaac
    13801 cactaggtta cgcaaaatct ttgttgcacc ttctttccct tcagactgag ccccataaga
    13861 tgttctgtca aaagcaaaat tgatagcctg acggaagttt ttattgagaa ctgcttcctg
    13921 agtcgatttc ttttcaatgt cacttgtttt agaagtataa ttgtaagact tcctatctag
    13981 gttaaaatta aagaaatatg aagttgaatt ttgcatacta tagatgatat tgtttttgta
    14041 tttttcttta atcccttcat agctggagct gttaggaaaa agacgagccg tagtataagc
    14101 accagctgta aaattacgtt ccagtgattc ttggtcgcta ccatcatagt aggtcaattt
    14161 cacatcgtct acaaagacat tcttagcatc ccagtaatta gggtttttct tatattcaat
    14221 agcagatttt gagacaagtg ctttcatcaa gaaaggtcca ttgtacaaaa tactagatgg
    14281 atccgccttc ccaaaatcat ccccttttga tttcaggaaa tctgcattaa caggaaaaag
    14341 tatcgttgca agtgtttttg aattccagta aagttctggt ttaaccaaag tatattgaac
    14401 cgtttggtca tcaagtgcct tgacaccgac agttgaaaag tcgcttgttt taccagtgat
    14461 atagtcatcc aaaccagcaa cagagtcctg cactagatac aaggcttctg attttttatc
    14521 agctgcatat tgcaaacctg tcacaaaatc ctgggcagtt acaggcgcat attcttctcc
    14581 ctcagaagta aaccacttgg catccttacg aagtttgtag gtataggtca aaccgtcctg
    14641 agaaacagtc caatcctctg ctaatgatgg aataatattc ccatattggt cattttctaa
    14701 taacccgtct accaaatttg caacaatatc ggatgttgct gcgcggtttt ctgctagata
    14761 gttcaagcta gatggatcac ttgaataaac atagttgtat gtttttgacg ccgtgctaga
    14821 atttccacac gcgctcaata aaactcctgt acccaggaca agacctgcca aggttagata
    14881 tttgctctta gactttttca tttccggaac ctcctgcttt aaatatttgt tttattatac
    14941 aacatttagt ttgtttagtc aatgattttt tccaaaaaat cgaaaaaagc ctcattttct
    15001 atttttgaaa tataatttta gctattttta cgctaaaaaa ggaataagct tcaagttctc
    15061 ctaaaagatt gttcaactta ttccttttat ttataaatgc taccttacga aagcttaaat
    15121 tttgctcgca ggcgatctgc ttgggctttt cctattacct tatctaataa ataggtacgc
    15181 agactcataa ccatataaag tccacccccc atggcaccga caagagctac ataaaggaag
    15241 ctccacaaac gtccacttgg ttggaagaaa aatcctaaca gccactggat ggttcctatt
    15301 aacagaaaca tgactagggt cagcaaactg attaaaatgg ttcgcttcaa aatcaccttg
    15361 cgcttgacac cagttacttt acaaatatcc cgatacatca agacgttagg aatgatgaga
    15421 gcaatggttg ttgaaatcaa aggaccataa ctgtggaaga gggcgatggt aggtagttgc
    15481 aagactagct tggcaataga accatagata aaatagagaa cggccttgcg gttgcggaac
    15541 atggcctgaa gcattggaga caagaccatg tacaagccta aaataataga ctgcaaaact
    15601 gcaaagacaa ataagcccag agccaaacta tctggcttac catagaagac cgtataaaga
    15661 ggttctccta ccataaccac tccaaccgtt gctggtagca agaacataaa gagtagggtg
    15721 agactgtcct gaacgagacg agaagctgct ttcaagtccc ccttgacata gttttccgtc
    15781 aaaagtggca aaccaacact cccaatcgaa acccctacag aaatcaaaat catcgtgatt
    15841 ttattaggat tggctgagaa ataagaaaac atgacaacca agtcctcatt gctgtagttg
    15901 gtaaaccagc tcatactatt gataaaggtc agctgatcca aaatctggaa gagctggatg
    15961 gcagaccctg tcaggataaa aggaatggct tccttaatgg tatcaaccaa gagacgctta
    16021 ctgttaatct tatctcctgt ttcaaagact cttttgagtg aaccttcttg ggcaaggaaa
    16081 taaatcaaga ctgcaaaact ggctaccata ccgacaaagg cagcaaaggt tgattgggta
    16141 acggctgcta gataatctcc tgaaccgagc ttcataatga taaaggttgc taggagcatc
    16201 cagataacac gaatgacctg ctcagcaatt tggctcatgg catagggttt gaggttattc
    16261 atcccttgga aaaatcctcg gataacactc atagacggga aaatcaagac tccccaagcc
    16321 aagctttgca tgattgggat caagtctttg cccacgccag acaagtctgc tagccaagga
    16381 gcaaagacat acaagactaa agcaaaaacc aggcctagtc ctgtcataaa gcctaagaag
    16441 ctccgaatca gggcaaagct atgctcttct tctcgcatgg tattatactt ggcaacttgc
    16501 ttggccaccg caactggaat ccccgctgtt gaaaccaaca agaaccaagc atagatattg
    16561 taacccatgg taaagagacc atttgcctta gctgcataag cccccatcca gatgtaccaa
    16621 gggataatgt aaacagcccc gagtaggcga ctgataaagt tactagccgt tagccaagca
    16681 gtcccccgta acatctgggc ctgctggtga ttgttttcgt gcgacataga ttcctcattc
    16741 aattttgata actaggaaaa actccttatc ttccattata aacttttcct tgttacttgt
    16801 aaatttgcga ctttcggttt acaatagaaa gtatgataaa aattgaaact gtattagata
    16861 ttttaaagaa agatggcctt tttcgcgaaa ttattgacca aggtcattac cactacaact
    16921 acagcaaagt tgtttttgat agcatcagct acgacagccg aaaagtaaca gaagacactc
    16981 ttttttttgc aaaaggcgct gcctttaaaa aagaatacct tctttctgct ataacacaag
    17041 gcttagcttg gtatatagct gaaaaggact acgaagtcgg tatccctgtc atcattgtga
    17101 acgatataaa gaaagccatg agtttgattg ccatggagtt ctatggtaat ccacaggaaa
    17161 aactcaaact ccttgccttt actggtacta agggtaagac aacagcagcc tatttcgcct
    17221 ataacatctt atctcaaggg catcgacctg ctatgttgtc gaccatgaac acaactcttg
    17281 atggagagac tttctttaag tcagcgttga caacccctga gagtattgac ctctttgaca
    17341 tgatgaatca ggctgtgcaa aatgaccgta cccacctcat catggaagtc tccagtcaag
    17401 cctatctggt caaacgtgtc tatggtctaa cctttgatgt gggagttttc ctaaatatca
    17461 gcctagacca tatcggcccg attgaacacc ctagctttga agactatttc taccacaagc
    17521 gtctcttgat ggaaaatagc cgagcagtca tcattaacag tgacatggac cacttctcag
    17581 tcttgaaaga acaggttgaa gatcaagacc atgatttcta tggtagccaa tttgataacc
    17641 aaatcgagaa ttccaaagcc tttagatttt cagctacggg taaactcgct ggagattatg
    17701 atatccaact cattggcaac ttcaaccaag aaaatgcagt tgctgctgga cttgcttgtc
    17761 tccgtctcgg agcaagtctt gaggacatca aaaaaggcat cgctgcaacc cgcgttcctg
    17821 gtcgtatgga agtcctcact cagaaaaatg gagccaaggt cttcatcgac tatgcccaca
    17881 atggggatag tctgaaaaaa ctcatcaatg tggttgaaac tcatcaaacc ggaaagattg
    17941 ctctggttct gggatcaaca ggaaacaagg gagaaagtcg tcgtaaggac tttggcctcc
    18001 tcctcaatca acaccctgag attcaagtct ttctgactgc tgatgaccct aactatgaag
    18061 acccaatggc cattgcagat gaaattagta gctacatcaa tcatcctgtt gagaagattg
    18121 cggatcgcca agaagccatc aaggcggcaa tggctatcac aaatcacgaa ttagatgcag
    18181 ttattattgc gggtaaggga gccgattgtt accaaatcat ccagggcaag aaagaatcct
    18241 acccaggaga tacagccgtc gcagaaaatt atttataaga atagaaaaaa tcaagggaaa
    18301 atgaaaccct tgattttttc ctattattta gtaaaaacgt ttttcaaacc ttcaacggca
    18361 ccttctacag caccttttgc gtcttctaca acgtcttttg ccttagcaac tgttttttca
    18421 acagctcctt caagttctgt cttgctgtct ccagtaactt taccaaaacc ttctttgaca
    18481 gcgcctgttg cttgttccaa tttgttttca agtgacatat gattgtctcc tttagtttat
    18541 tccgatatgt gttaccggtt acatatagtt tataccgaat actaaggaaa gtcaaacaat
    18601 gtactcagaa acaagaaatc acgctaagta gaaagttaac ctctccttat caaaatcgat
    18661 agccaactca tactttccat cttcattttg cacaatatag cctaagacaa cctaactgtc
    18721 cacaaagata tcacggcatt tctgcataag ctggtctttt ttgagaaatt tcaacaaaaa
    18781 agccgtcata tacttgaggg catactcagg attaacatct cctaaaatgt catagagctc
    18841 ctgctgtttt tctgtcaaag gatactgctg tttgaccttg taaaaataat tggacagggt
    18901 cattttaatg cgcgcaaagt ccgtcttttc aactaaaata gctgcattga tttgattgcg
    18961 caattccgtc tcaaaactct gctccaacaa ggcttgatag accggactag cttctctgac
    19021 aaaaatctct tgatccagtt caagactatc aagtgattca agcgtaggaa aattgaggta
    19081 atagcgctta ttttcacgta gaatcaagcc tgcctttata tactcttcca tgagtttatc
    19141 aactgcaaca tctggaaatt gagccttaat ttcccgtaga atcacatcct catactgatc
    19201 cagatagcgg atcaattctc caaaaatggc tgtctcgtca aacgagatgg attaaaaatc
    19261 tgaatcatga agattccttt ctttacattg taacagaggc gatgctgcca actgactagg
    19321 attggtacca gcttggttca gaggaacagg cagacctagt tctatgtaat actccctcca
    19381 aaaatcacta atctcctgct ccccatctcc aaatttcata ggaatagttt caaaaatagg
    19441 taggatttct gctatatact gggagcagta aaaaccagct gcatctggat agaaagaagc
    19501 attgtagggt gctccaagat gtttgcaagc tctttccttc accgactgga tatccatttc
    19561 tgggtaaaca tagaggtcgt ataaatgatt ggactcaaag aagtctgccg gttcttgaca
    19621 gacaacacca gcctgtccac tagcatgata aatcatccca tccaaataaa tggcaacatg
    19681 gctatagtta cctgtggaag tctggatggc ctgtcccatg tctgacccat ctctcacaaa
    19741 aatcaaatcg ccattttcta acatacttca ctcctagaaa aaaggagccg aaactccttt
    19801 cgatataagg caaactagac tttccgattt tgagctgaca cccaaaatct tacgcattaa
    19861 agctttcagt caattgaggt accacttgtt tcttacgtga aacggcacca gcaaggaagg
    19921 catgattgtt ttcaagtttg aagttgaaag ccgcttcgac cttgtccata ttgacaccaa
    19981 gagccaagat ttctgagttt gagttgacga tatctgtaat catcaagaca aagtcagagt
    20041 agccgtttga ttcgttggca gcttgcattg cagcttcaat ttctgcttgg cgttccaaaa
    20101 cttcagcgat gtcaactgtg ttcacttggg caacacggac attatttccg ttgagttcaa
    20161 aagtcttagc atcgatgtca atcaattctt cagcagattt gctagccaag ttggtaccag
    20221 ctttcaacat tgccaaacca tattcttcca agttcacacc agccaattca gccaattcag
    20281 gagcaatgat tttatctgtt gggtgtgttg ttggtgattt caaaagaagg gtatctgaaa
    20341 tcaaacctga aagcatcaaa cctgcaatct ctttaggcac agctacacca tgttctttga
    20401 acatacggta aacgattgaa gacgctgatc caactggctc caaacgcatg taaagtgggc
    20461 ttgcagtttc aaagttagcc acacggtggt ggtctacaac accgtaaact tctacttcag
    20521 cgatatctga tacagattgt tggaattcat tgtggtcagt caagataact tgctctgccc
    20581 cctctgcttt ggcagaagtg ataacacgtg gtgcttccac accaaaatag ttcaagacaa
    20641 aggctgtttc ttcatttgga gttccaaggg caacagcttc cgtatccaaa ccgtaagctt
    20701 cttttgcaag gtaggcaaaa gctacagatg acccgatggc atctgagtct ggattttggt
    20761 gaccaaatac tagaatcttg gacatgataa tacctcattt tgtttatttt ctttattgta
    20821 gcattttttt cgctttttga caaaggtaag aggagtcaaa ggactcccca cgattcttca
    20881 aaataactga gtaaatttct atcttgattt tcagataaaa attcttcctt ctgtggcctc
    20941 ttcttacgct tgagaagagc ttcagccgac atggcttctt ccttactggc aaaaccttga
    21001 gcatagataa gtttgactgg caagcgtgct cgtgtatatt tggctccctt cccactattg
    21061 tggatagcga ggcgtcttct cacatcagtc gtatagccta tatagtagga tccatcacga
    21121 cactccagaa cgtacatata agccttatga tccataataa atctcttcga tttcgggcgt
    21181 ataagagcca tcatcattgt ggacaatcaa aggaggtaag accttaaagc cacttgttga
    21241 gccatccttg atcgcctcaa tcaaaagcat attggcttcc ttttctcttt ttggataaac
    21301 aaactgcagg cgcttagggg ctagattatg tcgttttaac gtatccaaaa tatccagaag
    21361 tcgatcagga cgatgaacca tggccaaacg cccattagac ttgagaatac tctgggcact
    21421 acgacagatt tcttccaaat tagtcgtgat ttcgtgtcga gccaagagat aatgttcact
    21481 ctcgttcaga ttagaataag gatccacctt gaaatagggt ggattacaca aaatcatatc
    21541 caccttactc ccctgaatgt gagcaggcat atttttcaaa tcatcgcaga tgacctgcat
    21601 ttgttcctct aatccattca aacggacaga gcgttcagcc atatccgcca aacgctcctg
    21661 aatctcaaca gacaatatct gtgcttgagt acgagtgcta gcaaaaagcc ccactgctcc
    21721 attcccagca caaaaatcca caatcaaccc cttcttagga aaacgtggaa atcgtgataa
    21781 gagaacacta tccaccgaat aactaaaaac ctctctattt tgaatgattt tgatatctgt
    21841 cgaaaagagc tggttaatgc gctctcctga ttttaataat tgttcttctt ccatggtcct
    21901 attatagcaa atttatatta acattacaaa aaatataaaa ctctaaacta cttcttcttt
    21961 tttaaatggt gcagggcttc tccagtccag attggtagca ttcgtcgaaa gggagcaaag
    22021 ccgtagttaa agcggtcgct tgaaaagcgt ctccgtctag gaaactggta cttttcttcc
    22081 tccaaagtgc ggatagaaag actggctttc cctgtaaatt catctaaatc cactacctga
    22141 acttgaacct cttcatcgac tttcaaggtt tcatgaatat tttcaataaa tcctgtccga
    22201 atctctgaaa tgtgaatcag ccccgtatca cccgtctcta actcaacaaa ggcaccgtag
    22261 ggctgaatcc ctgtaatacg cccctttagc ttatcaccga ttttcatctt agtcctcgat
    22321 ttcaatagtt tcaattacaa catcttcaac tggcttgtcc atagctcctg tctcaacagc
    22381 agcaatggca tccaagacag cgtaagatgc ttcatcagct aactgaccaa aaatcgtgtg
    22441 acggcggtct aggtgaggtg tcccaccttg attggcatag atttctgcaa tcggttctgg
    22501 ccaaccacca cgagtaattt ctttcttaga ataaggtagg tgttggtttt gcacgataaa
    22561 gaactggctg ccgttggtat ttggaccagc atttgccatg gaaagagcac cacggatatt
    22621 gtaaagctct tctgagaatt catcctcaaa agattcgccg tagattgact ggccacccat
    22681 accagttcca gttgggtctc caccttggat cataaagtcc ttgataatac ggtggaaaat
    22741 gacaccatca tagtagccat cttttgaaag agatacaaag ttagccactg ttttaggagc
    22801 atgttcaggg aaaagcttga tacgtaagtc tccgtgattg gtcttaatag tcgcaagagg
    22861 accttctact gtttcaatgt ctacttgtgg aaaatgcaat tctttttcta ccataccaaa
    22921 tacttctaag gcagcaaaaa tgccatcttc ttctaatgtt tttgtaatat aatctgcttt
    22981 ttctttgatt ttatcatgag aaattcccat ggcaacgctg attccagcat aatcaaagag
    23041 ttccaagtcg ttgagaccat ctccaaaaac catgaccttc tctggtttca agccaaggtg
    23101 ttccacaacc ttttccaccc ccgtcgcttt ggagcctgaa atcggcacaa tatcagacga
    23161 atgttgatgc caacgaacca tgcgaagttt gtctgagaga ctgtcaggca agtgcaagtc
    23221 atctccctta tcttcaaaag tccacatctg atagatatct tctttttcat ggaaatcggg
    23281 atctacatct aagtcgggat aaattggatt gatagcttca ctcatcatat cggtgcgagt
    23341 cgacaacttg gcatcatgac tcccaaccaa gccatactca attccttctt gcttagccca
    23401 agagatatac tcctcaacat ctgacttttc aatctgatgc tgataaatga cctgaccttt
    23461 tttatcttcg atataagccc cattcaaagt tacaaaaaag tcaggcttga gatcacgaat
    23521 ctctggaaca acaccaaaaa tgccacgtcc agaggcgatt cctgttaaaa ttcctttttc
    23581 acgcaactgt ttaaaaacag tggggattgt agttggaata aaccctgtct ttgaattccg
    23641 caatgtatca tcaatatcaa aaaagacaat cttgatcttc tttgccttgt atcttaattt
    23701 cgcgtccatc tcactacctc tttcaatcta actctttcca ttatatcata aagtaggcaa
    23761 atcccctatt ttcaaaaagt ttatcatttt tattttaatt tcttggatga gaaaagagac
    23821 atatttatga aaaagctcca tcgtgctttt aatgtgttct cttgttttca aactcgtaaa
    23881 aagggagcca ctgagcctaa ctcgctctct catttcaaat cttgtgaaaa aagacccgtt
    23941 ggggtcttaa ttcgctttct tgttttcaag ctcatgaaaa agagacccaa tcgggtcttt
    24001 tctttaatct tcgtttacga aaggcatcaa agccattacg cgagcacgtt tgatagctgt
    24061 tgttacttta cgttggtttt tagctgaagt tcctgttaca cgacgaggaa ggattttccc
    24121 acgttctgaa acgaaacggc taagaagctc agtatctttg taatcaacat attcaatttt
    24181 gtttgctgcg atgtaatcaa cttttttacg gcgtttgaat ccgccacgac gttgttgagc
    24241 catgtttttt ctcctttata agtttagttg tccattagaa tggtaaatca tcatcagaaa
    24301 tatccaatgg gtttgttgct ccaaatggat tttcattacg tgaaaagtct ggtactgaat
    24361 ttgtaggtgc tgaatagttt gcagttggtg cagagtaagc tccacctgtg tgaccctcac
    24421 gcacactacg gctttccaac atttggaaat tctcagccac gacctctgtc acgtagacac
    24481 gttgtccttg ctggttatcg taactacgag tctggatacg acctgtcacc ccgataagtg
    24541 agcctttttt agcccagtta gcaagatttt cagcctgttg gcgccacata acgacattga
    24601 taaaatcagc ctcacgttca ccattttgac tcttaaatgt acggtttact gcaagagtaa
    24661 aagtcgcaac tgctacattt gatggggtat aacgcaactc agcgtcacgt gtcatacgcc
    24721 ctacaagtac aacattgtta atcatagttt accttcttac gcgtcaattt tgacgatcat
    24781 gtgacgaaga atgtcagcgt tgatttttga aagacggtca aactctttaa gagctgcatc
    24841 gtcatttgct tcaacgttaa cgatgtggta aagtccttca cggaaatctt ggatttcgta
    24901 tgcaagacga cgtttttccc aagtttttga ttcaacaaca gttgcaccgt tatcagtcaa
    24961 aatagagtca aaacgtgcta ccaaagcgtt tttagcttct tcttcaatgt ttggacgaat
    25021 gatataaaga atttcgtatt tagccattga tatgttcctc cttttggtct aatgacccca
    25081 agactttgca aggggtaagt gaggttcgct cacaataaat tattatacta gaaaaaattt
    25141 ttttacgcaa gtaaaaacac tagaattcga aaaaacgcca catgggcgtt ttcctgttct
    25201 tatggtttga tacggtgcaa catacgtggg aatggaatag cttcacggat atgttttgtt
    25261 cctgctgcaa aggttaccat acgttcgata ccgataccaa atcctccgtg tggaactgta
    25321 ccgtatttac gaaggtcaag gtagaattca tattctgtac gatccatacc aagttcatcc
    25381 atcttagcga caagggcatc gtaatcttcc tcacgcatag acccaccgat aatttctcca
    25441 tagccttctg gagcaagcaa gtctgcacaa agcacgcgct ctggatttcc aggaactggt
    25501 ttcatgtaga aagccttgat ggctgctgga tagttcatga caaatgttgg cacaccaaag
    25561 tggtttgaaa tccaagtttc gtgtggtgac ccaaagtcat caccatgctc aagatgctcg
    25621 tagtcagcat cttcatcatt ttcatgctct tgcaagaggt caatggcttg atcgtaagtg
    25681 atacgtttga atggctctgc aatgtagcgt ttcaagagtt ctgtatcacg ttccaagatt
    25741 tccaaggctt gaggcgcgcg gtcaagaaca ccttgtagaa gagctttcac ataagcttct
    25801 tgcaagtcaa gcgactcatc atgtgtcaag tatgagtact cagcatccat catccagaac
    25861 tcagtcaagt gacggcgtgt ttttgatttt tcagcacgga aaactggacc aaagtcaaag
    25921 acacgaccaa gagccatagc ccctgcttct aggtaaagct gacctgattg gctcaagtag
    25981 gctggcgttc cgaagtagtc agtttcaaag agttctgtag aatcttctgc cgcatttcct
    26041 gaaagaattg ggctgtcaaa cttcataaaa ccgttcttgt caaagaactc ataagttgca
    26101 tagataatag cgttacggat ttgcaacaca gctacttgct tacgagagcg tagccacaag
    26161 tgacggttat ccatcaaaaa gtctgttccg tgttcttttg gtgtgattgg gtagtcttga
    26221 gattcaccga tcacttcgat gtctgtgatg tccaactcat agccaaattt agaacgttcg
    26281 tcctctttga caatacctgt cacataaaca gacgtttctt ggctcaagcg tttgataaca
    26341 tcaaacttct caagtcccac ttcttcacca aatttttcga caaagtttgg tttaaaagcc
    26401 acaccttgaa agaaggctgt tccatcacgc aattgtaaga aagcgatttt tccttttcct
    26461 gatttgttgg caacccaagc gccaatcgtc acttcctgac caacatagtc ttttacgtca
    26521 ataatcgtta cacgttttgt cattattttt ccttttcttt tttattcttt atggcaaacc
    26581 acctctatat tgttcccatc caggtcaatc ataaaagcag catagtaaat cagacgctca
    26641 cttcgataac caggagcccc attgtctcgc ccacctgcct ctaagccagc ctcataacaa
    26701 gcctgaactt cttccttatt ttctgctaaa aaagcaaaat gaacaggatc ttgtgttccc
    26761 tgagtcagcc aaaaatcacc accaggatga gggctgttcg gggatagaaa actaattaga
    26821 gaactagtct taaaagccaa tttatagtcc aaaggagcga gaaaactcct ataaaatcct
    26881 tctgaaattt gtaaatcctt taccttaatc tcaaaatgat caatcattct cactacccat
    26941 aaatgctttc aagcgttcga ctgcttcttt aagcgtgtct aggtctgtcg catagctgag
    27001 gcggacattt tctggtgctc caaatccagc tcctgttacc aaggccactt cggcttcttc
    27061 taagatagca gttgtaaagt ctgtcacatc cgtgtagcct ttcatctcca tggccttttt
    27121 gacatttggg aagagataga aggccccttg cggtttgacc acttcaaatc ctggcacttc
    27181 tgcaaggagg ggatagatgg tattaagacg ttcctcaaag gcctgacgca tgctttctac
    27241 agtatcttgc tcacctgata gagcctcaac tgctgcatat tgtgctactg ctgacggatt
    27301 cgaagttgtt tgacctgcaa tcttggacat ggcagcgata atgtctgctt ctccaacggc
    27361 ataaccaatc cgccaaccag tcatggcata ggttttagac acaccattga tgaccactgt
    27421 ttgcttgcga atcgcttccg ataggctaga aatcggtgtg aactcatgac cattataaac
    27481 caagcggcca tagatatcgt ctgctaggat gagaatatca ttttctacag cccagtttcc
    27541 aattgccaag agttcctcac gggtgtaaat catacctgtg ggattagatg gcgaattcag
    27601 caccaaaacc ttggtcttgt cagtgcgagc tgcttctaac tgctctacgg tcaccttaaa
    27661 gtgattgtct tccttagcag aaacaaagac gggaacgcct tctgccatct tgacctgatc
    27721 tccatagcta acccagtatg gggttgggat gatgacttca tcacctggat tgaccacagc
    27781 cataaagaag gtatagagag aatatttggc tcccgcagcg actgtcactt gatttgatgc
    27841 tacagaatag ccgtaaaagc gctcaaagta gctattgacc gcctccttaa gctctggcag
    27901 acctgaggtt actgtataaa aagaagcacg cccatctcga atcgatgcaa tggcggcatc
    27961 ttggatattt ttgggagtag tgaaatctgg ctcacccaag gttagagaca aaatatctct
    28021 actctcagcc ttcagtgctt tggcacgggc tccagcagcc aaagtcacac tttcttccat
    28081 ttctaaaaca cggttggata gtttcatagg ccctccttgt tgaccaatgc tcctgtttca
    28141 aaatctacta gataaaaatc agatcctgac ttaacttccc agattggctt atcttgataa
    28201 cggccaaagg ttatcttgtc aatctcgcca gctccctttt ccttagaaac cgtttctgct
    28261 ttttcttgtg aaacaccctg atttagctga taaacgtaaa tcttatggtc atctttacca
    28321 atcaggacag caagcgcttc ttgctgttta ttacgaccaa gaacgctgta ataagattcc
    28381 aagccattgt ataaatcaac ctgatcgacc tgctctaatc ctgcatactg ctgagctaat
    28441 ttttctcctt cacttttagc tgtttgatag ggtttcatgc taagagaaac catatacaga
    28501 aaggaagcac tgataaccac aaacaaaatc gtcatcccta gaccatactg ccacagtaga
    28561 ttattttttg ctttgttttg tctttttttc actcgtctat tttaccatct attaagcttt
    28621 attacaagtg aatataagaa tactcttcga aaatctcttc aaaccacgtc agctttatct
    28681 gcaacctcaa agctgtgctt tgagcaacca attctatttc tcccttcaaa caaaaccgat
    28741 tttgaaagtg aaacagttct tactttttca gtcacaaatg attagagttt ccgaaatttt
    28801 acaattttca aataaactct gagcaaattt cttgcaagtt cttttgtttt gttgtaatat
    28861 attttataac aacgagagag ttctcgaaat tttaagaaaa aggagacaca tcatgtctaa
    28921 aaaagtatta tttatcgtcg gatcactacg tcaaggttct ttcaaccacc aaatggcgct
    28981 cgaagctgag aaagcacttg ctggtaaagc ggaagttagc taccttgatt attcagccct
    29041 tcctctcttc agccaagatt tggaagttcc aacacatcca gctgtagctg ctgctcgtga
    29101 agcagttctc gttgcggatg ctatctggat tttctctcca gtctacaact tctctatccc
    29161 tggtacagtg aaaaacttgc ttgactggct atctcgtgcc cttgacttgt ctgatacacg
    29221 tggcgtttct gcccttcaag acaagtttgt cacagtatca tctgtagcca atgcagggca
    29281 cgatcaactt ttcgctatct acaaagacct cttgccattt atccgtacac aaggcgttgg
    29341 tgatttcact gctgcacgtg ttaatgactc tgcctgggca gacggaaaat tggttcttga
    29401 agaaacagtc ctaaactcac ttgaaaaaca agctcaagac ttggtcgaag ctatcaagta
    29461 actaacactc aataaaaatc aaaaagcaaa ctaggaagct agccacaagc tgctcaaagc
    29521 actgctttga ggttgtagat agaactgacg aagtcagtga catatatacg gtaaggcgac
    29581 gctgacgtgg cttgaagaga ttttcgaaga gtataacata ataaaagcga acaagactac
    29641 ttttctgaca ctcagaagac tagcttgttc gctttttttc tcatttataa actaaaacag
    29701 ctgatgatac atattgccaa atacaaaata tctgatttct atacttcctt tacaaaaacc
    29761 aatccctgtg gttgtgacaa atcttctcga taaacaaatc cagcaaagtt caagcgacgt
    29821 gcttccccca cagtttgtac ttgattttct attaaagctg ttagaaaggc cccgcgcgct
    29881 ttcttggaga tagttgagtg aatcttcagc tgaccgcctc tatcctccat gaatttgaag
    29941 gtcaccatct ttgctctgat ttccttagaa aatacagtct caaactctga tgacaagaga
    30001 gagaaaatca cttcttcctt cttcagagct tcatcataga ctgctttcca atggctcttc
    30061 aaagtcttac cagcgacttt taatttcatc aaaaaatcca aacggtgagg agccatgagt
    30121 gacaaggctg gaacaacacc gtacaaagcc gaggtaatga agacatgatt ttcaagataa
    30181 tcttgttccg cctcggtcag cttatctctc ttaatgttgc ggtacataag cccatcaaaa
    30241 agtttcaagg ctggatagtg ttgagcagtt tgccttttca aagcttggat attttgaaat
    30301 tcttccgccg ctttctcagc tgataccttg tagaaactct ccaattgact ggcagaatag
    30361 agagccaagg catcaagcac ggcctgactt tctggtttta aaggaattgc ctcgatactt
    30421 ggcaagtctg tgttcatttc ttttgctgtt gggattaaaa ttttcatatt gatagtgtag
    30481 catatttttt agccacaacc aagaaattca tttgaaaaac ctcggtttga ccgaggtttt
    30541 tctatttatt tgggccatcc taaccagaca gccacgagaa caagggctgt gccagctaaa
    30601 cttgttaaga tagataagaa tttatctttt ttctccttga actgagaaaa acctatcttc
    30661 aaagcgagca gtccgagtag cattgaagca accatcaaat aaaaacccat ttctttgtcc
    30721 tccattaggc ttaatttacc ttattataac atatatttct taaataaacc ttttttatac
    30781 tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag gctgctcaaa acactgtttt
    30841 gaggttgcag atagagctga cgtagtttga agagattttc gaagagtatt attgtacttt
    30901 aaaggtcttg agatagttgt cttttcctac ttgaccttcg aaggttttac cattttcaag
    30961 gtaaggaagg tcatcggata ctgaagcctt taccttgtat atcttgctat caactttaaa
    31021 gaagtagaca gtgtctccct tgataacagc tgatttgagg tctgctacta ctcccttgat
    31081 gctttctgtc gttgcattgt caatttcaag gtcgttttta ttggcatact tgctgagcat
    31141 ctcttccact gtagtagcaa cgataacatt ttggtactcg actgcgtcta ccagggcgta
    31201 ctctttgacc aagccagcat tgtcctttaa gcccatgatg tagagaggct tgtcattgag
    31261 gttgatgagg attgggaagg ttgctttgta ggatttctcc tgaacagcac cttctgctga
    31321 ttcacgggct gattcttctg tcgcagaagc caagctatac ttagtaattt ctcctgttcg
    31381 catattttca aggatgaaac caagattact ctcatccgca ttagccgacg tcacacctgt
    31441 gtagagatag atgtcattac cgatagacaa gtaattatag ccattggtag tctgggtcac
    31501 gtttttcttg gaaatcatgg cattcaagaa accgtccttg tacttgccgt tgtagttgat
    31561 ttgctcaatg gtttcctctg ctggatagat cctgtccacc cattctggaa catctgataa
    31621 gctgtattcc ttggtttctc catttgtagc atccaagata atgactgaag caggacgagg
    31681 aacagcaagt ccaaattgct tttggtaaac cgttgctaca tagaaaggat tgccctcatc
    31741 gtccacctca aaagatggag ttttaaagat tttggtcggg tacttcaagc gcaggtgacg
    31801 tttgacatca cggttaaaat actccgagtc tgaatacttg attggtgtct tcaagtccac
    31861 caaatccgca tttccagtta ccatgtccac cttgatatac tcaccgattc ccttggcttg
    31921 attgttaaac catttgatag ggtctgcata ttctagtggt gtgacccgat aaggtttccc
    31981 atcaattgtc aattgggtat aggtatctgc cgctacgtat tgcgacacct tatcggttag
    32041 ggaacccaag tagcggtctc caattttttc agcagtactt ctatctagga taggaacctt
    32101 actggtgtca ctcttaggaa attcagtaaa gtctttttcc gtaaccgtga ctacattggc
    32161 ataattttta gcctgaaaca tgctggaagt taccaaggaa accaaagctg ccaagagaag
    32221 aattcctcca atcgaagcta acagaatttt ccctaaccga ttgattttga aaccctcaag
    32281 atttaaggca gcttccgcct taccgtggcg cacatgaacc gttttgacaa ggtttatccc
    32341 cttgccaaag ccaaataata ttgccacaac taacaaatgc ccacagagga agaagagaaa
    32401 ttcccagctg gtcaggttaa ggggcggtaa aaagatatac caggtcgttg cgataaaaat
    32461 aagttcaaag actattcgtt tcatttgctt tcctcctaaa tgattcgtcc ttccaagtga
    32521 tccagctcat gctggcaaat ctgagctggg aagcctgtca aggtaatggt ctgttcctgc
    32581 cacttgctgt cacgataggc aagccttatg gtttcataac gcttagttga tctcacacct
    32641 accaaggaca aacagccttc ttctgcctca taggatcctt caaaggacag aagcactggg
    32701 ttaaacatga ccacgggaac caagccaaga ttaaagataa tcacgcgctt ctgcacccca
    32761 atcatattgg cagctagacc aacacaggta tcacgatttg ctaagagtgt atcctgcaaa
    32821 tctctggcaa gataaaggtc ctcctgactt gccggcttag acacttgaga taaaaataag
    32881 atatccttca caattttctt ttccacttcc tcacactcct cttgcttttt actatattat
    32941 agcaattata gcacaaaagc cgataactgc aaaccctttc cctcaactgt agcaaaaagc
    33001 catccgaaga tgactttttt gctatttaat ttctgtataa gttacttcca agccacgctt
    33061 aacagctgga cgattggcaa ttttttctgc ccattttact agattttgat aacttgaggc
    33121 atccaagaat tttgcagaac cttggtaaag atttccttga actaactgtc cataccaaga
    33181 ccagatagca atatctgcaa tcgtatagtc attgcctgca atataaggtt tctgagccaa
    33241 ttccttatcc aataaatcca actggcgttt cacttccatc gtaaaacggt taataggata
    33301 ttccaatttt tcaggagcat aattgaagaa atgtccaaat cccccaccta gaaaaggtgc
    33361 tgcacctgct tgccagaata gccaattcaa aacttctacc ttttccacag gattacttgg
    33421 taaaaaggct ccaaatttct cagcaaggta aagaagaata tgagcagact caaagactct
    33481 tacgttttca gtacctgact ggtccaataa ggctggaatc ttggaatttg gattgagctt
    33541 cacaaagtct gagccgaatt gatccccatc catgatagca atcttataca agtcgtaagc
    33601 cgcttcctta aaaccagctt ctagtaattc ttccaataag atagtaacct tcacaccatt
    33661 tggtgttccc agtgaataaa gctgaaaagc ttgttctcct tttggcaagt tttgttcgaa
    33721 acgggcacct gctgttggtc tgtttagccc cgtaaaagct ccttgattac tagcttcatc
    33781 ctgccataca gtcggtaatt gatatgctga catccgaaac ctcccttaaa tcgcattctt
    33841 gtcaaaaccg agtttgcgtt gaataaactt aacgatttcg acgatgataa tcattgagaa
    33901 gcttccagcc ataacaattc cccattgtga caagtctagt ttggttacgt ggaagattcc
    33961 ttcaagcggt tctacaacga ttgttgccat gagaaggata aaggatacca agatggacca
    34021 gttaaaggtc ttagacttga atgggccaac tgtcaagatg gattggtaga cagacttgac
    34081 attgtaggca tggaagagct gaatcaaacc aagggttgca aaggccatcg ttagggcatc
    34141 tgcatgaata gcatgattgt cacccacatg aactgggtaa gcaatcgcaa ggccataaac
    34201 actcataaca agagctgctt ggagtacacc ttgataaatg atagaactca aaacaccacc
    34261 tgagaagaag cttgccttgc gtccacgtgg tttatgattc atgacaccag gctccgcagg
    34321 ttcaacacca agagcgatag ctgggaaggt atccgttacc aagttgatcc acaaaagatg
    34381 aaccggctgc aagacatccc aaccaaacaa ggttgatagg aagatggtta atacttcagc
    34441 agtattagca gaaagtaggt actgaatagt cttttgaatg tttgagaaga ccttacgtcc
    34501 ttcttccact gcgacgataa tagtcgcaaa gttatcatct gcaagaatca tgtcagaagc
    34561 ccccttagaa acttctgtac cagtgattcc cataccgata ccgatatcgg ctgttttcag
    34621 agctggcgcg tcattgacac catcacctgt catggcaacg actttacctt gtttttgcca
    34681 agccttgacg atacgaacct tgtgttctgg agacacacgg gcataaacag agtattgacc
    34741 aacgactttt tcaaattctt catctgacag ttcattgagt tcagcaccag ttaaaacgtg
    34801 accttctgta tcgtttgcgt caatgattcc caaacgtttg gcaatggctt ccgctgtgtc
    34861 ttggtggtca cctgtaatca taattggacg gattcccgct tccttagcca cacgaacagc
    34921 ctcagcggct tcaggacgtt cagggtcaat catcccaatc aaaccagtaa aaattaaatc
    34981 attttcaagc tcttcagaag tgagattttc tggaatacta tcgataatct tataagcacc
    35041 tgcaaggaca cgcaaggctt gatgagccat ttcagaattg tttgtatgaa tgagatttgt
    35101 aaccttctca tcaatcggag caatatcccc agccttatca cgaagaagac aacgctttaa
    35161 gagttggtct ggcgcaccct tgactgctac aaggaaacga ccatctggca atgggtgaac
    35221 tgttgacatg agcttacggt cagagtcaaa tggcaattca gctacacgag gatatttctc
    35281 taagaaacct ttgacatcat agcccttgtc caaggcatat tggataaagg ctgtttcggt
    35341 tgggtcacca atcaagttac cttccacatc gattttcgta tcattggcca agacaactga
    35401 acgaagtagt ggcatttcaa gacctagttc aatatcatca gctgagtcat gtagaaccgc
    35461 atcgtagaag actttttcga ctgtcatctt gttcatagtc agcgtaccag tcttatcaga
    35521 agcgatgatt tcagttgaac caagtgtttc aactgctggc aacttacgaa cgatggaatg
    35581 tcgtttggcc aaaacttgag taccaagaga aagaacgatg gtaacgatag caggaagtcc
    35641 ttctggaatg gctgcaacgg caagggcaac agaagtcaac aactcaccaa gtggattttt
    35701 cccttgaatg aagacaccca ctacaaaagt aacaagggca atgaccaaga tagcataggt
    35761 caagacctta gaaaggttgt tcaagttttg tttgagtggt gtatcagtct catccgcatc
    35821 ttgaagcata ccagcaatat gaccaacttc agtatacata cctgtattga caacaacacc
    35881 catcccacga ccataggtta cgtttgagtt ttggaaggcc atgttgacac ggtcaccaat
    35941 accagcatct gtcgcaagct cgactgacaa gtctttttcg actggtacag attcacctgt
    36001 caaggctgct tcttcaattt taagagagtt ggcttctagc aaacgtaggt ccgctggtac
    36061 cacgtcacct gcttcaaggg caacgatatc gcctggtacc aattctttag agtcaatctc
    36121 tgccatgtgt ccatcacgaa gaacgcgggc aactggacta gacatggatt tgagggcttc
    36181 gatagcttct tcagcttttc cttcttggta aacaccaaag gcagcgttga tgataaccac
    36241 agctaggatg ataatggcat ctgcgatatc ttccccacca gaagtcacga ctgacaagat
    36301 tgctgccgca actaggatga taatcatcaa atccttaaat tgctcgatga atttgaccaa
    36361 gattgatcgt ttctcgcctt cttcgagttc attgtgccca aattcggcaa ggcgcttttc
    36421 cgcctcactt gatgacaaac cttgctcggt cgcatccaca gcctgcaaga cctcttcagg
    36481 gctctgagta taaaacgctt ggcgtttttg ttcttttgac atgtgtctcc tccttgacat
    36541 tgtgtgcaaa acagactctc tttctgtcat atcttttcac gacaaacaaa aagagacctg
    36601 ttaatcataa caagtctcgc tgtttaagat agggccggaa agcatacttt tcagcataaa
    36661 attcggaatg acgacactat cacaggtttc tgccagctac tcccttgagt agtactatta
    36721 taccaaattt tggggagttt tcaaagagta aaaactacct tatttgaatt tttccttgaa
    36781 aaccagtata atggtagaat gctatgtgac tagaaaggaa gttgaatgaa gcaatctatc
    36841 tcaaatctca agttagctga gcgtggagct attatcagta tttcgaccta tttgatcttg
    36901 tctgcagcca aattagcagc tggtcatctc cttcattcat ccagtttggt ggccgatggt
    36961 tttaataacg tatcggacat cattggaaat gtggccctct taatcgggat tcggatggcg
    37021 cgccagcctg cagaccgtga ccaccgtttt ggtcattgga agattgaaga tttggcaagc
    37081 ttgatcactt ctatcatcat gttctatgtc ggtttcgatg ttctaagaga taccattcaa
    37141 aagattctca gtcgggaaga aacggtcatt gatcctcttg gtgcaactct aggaatcatt
    37201 tctgcagcga ttatgtttgt ggtctatctc tacaatactc gcctcagtaa gaaatccaac
    37261 tccaaggcgc tgaaggcagc tgctaaggac aatctttctg acgctgttac ctcacttgga
    37321 accgccattg ccatcctagc tagtagtttc aattatccga ttgtggataa actggttgct
    37381 atcatcatca ctttctttat cttgaagact gcctatgata tcttcatcga gtcttccttt
    37441 agtctttcag atggctttga cgaccgcctg ctcgaggact accaaaaggc tatcatggaa
    37501 attcctaaaa tcagcaaggt caaatcgcaa agaggtcgca cctacggtag caacatctac
    37561 ctggatatta cactagagat gaatcctgac ttgtctgttt ttgaaagcca tgaaatcgcg
    37621 gatcaggtcg agtctatgct ggaggatcgt tttggcgtct ttgataccga tgtccatatc
    37681 gaaccagcac ctatccctga ggatgaaatt ttagacaatg tctataaaaa attgcttatg
    37741 cgtgaacaat tgattgacca aggaaaccaa ctagaagaac tcttgactga tgattttgtc
    37801 tatattcgcc aagatggaga gcagatggat aaagaggctt ataagaccaa aaaagagtta
    37861 aattctgcta tcaaggacat tcaaattact tccatcagtc aaaaaaccaa actcatctgc
    37921 tatgagttag atggtatcat ccataccagt atctggcgtc gccacgaaac ctggcaaaat
    37981 atctttcatc aagaaaccaa aaaagaatag agaaatcctt tcatgagacg ggatttttct
    38041 attcttttat actcaataaa aatcaaagtg caaattagga agccggtcac aggctgtact
    38101 tgagtcggca atgtgaagcc gacatagttt gcactttgat tttcgaatag tcttaactat
    38161 caaattcact gagatactca tagcgttcgt atttttcaag gagtgcttca tttttctcat
    38221 ccaattcttt ttggagagta gccagcttac caaagtcaga gccgttagcc tgcatttcct
    38281 cttcaatagc agcgatacgt ttttccaagg tttcaatatc accttcaata cttgcccact
    38341 cctgcttttc ttggtaggtc atgcgtttct tgtcttctcg aaccttgacc actttttcct
    38401 tttcggcctt ttgcacttga ttggccatat ctgtttcaaa agctttttca tcaagatagt
    38461 cggtgtaatg accaaagaaa ggacgaatct tgccatcctc aaaagcgaga atcttggtcg
    38521 ctaccttatc caagaaatag cggtcgtgac tgactgttaa aacgggacct gcaaaacctt
    38581 gcaagaaatt ctccaagact gtcaaagttg caatatccaa gtcattggtt ggctcgtcta
    38641 aaagaagaac atttggtttt tccaagagca gtttgaggag ataaagacgt tttttctcac
    38701 caccagataa tttctcaatc aaggttccat gcgtcgaacg tgggaaaagg aactgctcca
    38761 gcaactctgc aatcgaagtc gtagaaccgc cactggtctt gacctcctct gccacttcct
    38821 gcaggtaatt gataactctc ttgctttcat ccaaaccctc aatttgctga gagaaatagg
    38881 cgatgcgaac agtttcccca atcacaactt gtcctttagt tgactcaaga cttcctgcaa
    38941 ttaagttgag taaggttgat tttccaacac cattgtcccc aacaattcca atacggtctt
    39001 tagcctgaac taagagatta aaattttgca aaatgggctt attttcatag gcaaaggaaa
    39061 catcctgaaa ctcgatgact ttcttcccaa tccgactggt ttcaaagttc atagtcaagt
    39121 ctgtctcagc actactgcct gaaacttcct ttttcagatc atggaaacga ttgatacgag
    39181 cttgttgctt ggtcgcacgt gcctgcggtt gtctgcgcat ccaggccagt tcttgtttgt
    39241 agagttgttc ttttttatga agtagagctg catcgcgctc gtcctgttct gccttaaggc
    39301 gaacatagtc ctggtaattg ccctgatatt ctgtcaagcc tgctcgctcc aactcgaaaa
    39361 tccgtgttga caaagcgtct aagaaataac gatcgtgagt gataaaaagg acggtcttct
    39421 tagaattttt caaaaagagg gtcagccact caataatcgc aatatccaga tggttggtcg
    39481 gctcatccaa aagcaaaagg tcgtggttgc caagtaagac ttgtgccaac tgtacccgtc
    39541 ttctcagacc acctgacaat tccccaacag gagtagataa gtcttgaatg cccaatttgc
    39601 taagaacggt cttgacctga ctttcgattt cccaagcttg gagagagtcc atctctgcca
    39661 tgacacgttc caaacgcgcc tgcttgtcct cactatagtc gagcataatc aattcatact
    39721 cacgaatgag ctggatttcc ttgagttcac tagatagaac cgtatccaaa actgtctttc
    39781 tatcatcaaa atcaggatcc tgagtcaagt aaccaatctg gtaatcattt ttagctgaaa
    39841 aaggactgac atccccatca aatccagaaa caccagaaag gacgtccaaa agggtggtct
    39901 tgccagtccc attgacaccg attaaaccaa ttctgtctaa gtcatggata ataaaggaaa
    39961 tatccctaaa aacggtcttg tcaccaacgg atttacttag tttttcaacg ataaaatcac
    40021 tcattttttc tccctcaggt aagcatggat ggcttcacga ttattctcca attctccatc
    40081 gacaatggca aactcaatct ctgttaaaat ctctcccaag tctgggcctg gctgatagcc
    40141 atattccttg atcaaaatac cgccattaat ctgaatatct ttcttgtcat ggatagtcaa
    40201 gctttggtat ttttctgtga tggcttgtgg gttgacttct tttccttgag cttgacgaag
    40261 attttcagcc tgtaaaagca aatctatgtc aaagcgataa caatctcgct tgctcaattc
    40321 tccattttca cgcagagcca aaataatcag caaatcctga acttgcttgg caaactggcg
    40381 tgaggtcttc caagatttca aaaatgactg cgcattttca atctccaaag cccatagtaa
    40441 agccgcccag gcttgttcag aggattcaaa agtaaaatca gtctccaaat caaacagtct
    40501 gttgagcttg tcctggctag atgccatatc agggagatag tcataagctt gactctcaat
    40561 catggaagcc aagccccttc tccaaaatgg agccagcaag agtttatcaa actcgacgaa
    40621 ggtacgctct acagaaattt tctccaaaag cggcgtcaag gtcttcatag ctttaaatgt
    40681 ttctggctca agtgcaaaac caagactagc ctgaaaacgg aaaccacgca taatccgtaa
    40741 agcatcttcg ttgaaacgct cactagccac tccaactgct cgcaagactt gcttttccaa
    40801 atcttctaaa ccatggaaca agtcaacgat ttctcctgtc tcatccaagg caaaggcgtt
    40861 gactgtgaaa tcacggcgtt tgaggtcttc ttctagcgag cgcacaaagg aaaccgcact
    40921 gggtctgcga tagtccacat agacatcctc tgtccgaaag gttgttacct catactcctc
    40981 atccccatct aagaccaaga cggttccatg ctcgattccg atatcggctg ttcgcggaaa
    41041 aatctgcttg gtctcttctg gataagaaga cgtcgcaata tccacatcgt ggatagggct
    41101 atggagaagg gcatctcgaa cagagccccc aacaaaataa gcctcaaagc ctgcttcttt
    41161 aattttttct aatactggta aagccttctg aaattcagaa ggcatttgcg ttaatctcat
    41221 aataagtgtt ctaatccata gacaagctca tgacgcttga caacttcttt aattcccaaa
    41281 ttgactcctg tcatgaagga gatgcgatca taggagtcat gacggagggt caacccttct
    41341 ccctgattgc caaagatgac ttcttgatga gctaccaagc ctggcaaacg aactgagtgg
    41401 atgcgcatac catcaaagtc agcaccacga gcaccagcaa tcagctcttc ctcatctgct
    41461 gcgccttgct gaatggactc tcgaacctct gccatcaact cagctgtttt aatggctgtt
    41521 ccactcggag catccttttt cttgtcatga tggagctcaa taatctccac atttgggaaa
    41581 tatttggcag cctgcgtcgc aaattgcatg agtaagacag cacccaaggc aaagttaggg
    41641 gcaatcaggc cacccaagtc ttgggcacga gaaaattctt ttagctctgc aatttcttca
    41701 ctcgtgaaac cagtcgttcc aactactgga gcaaagccat tttcaagagc aaaacgtgta
    41761 ttttcgtagg caacagctgg agtagtaaag tctacccaga catccgcttc aaaaccagct
    41821 aaatcagcct tatccttgaa aacaggaata ccctgccatt ctgactcaga ctcaaaagga
    41881 tccaaaactg ctaccaagtc caaatctgaa tcagtcaaga ccatctggca agcagcttga
    41941 cccatctttc ccttaaaacc ggcaataatt actcgaatac tcatctctac tcctgtctaa
    42001 gatacaaagc ctgtaagaac acaaagtgaa aataggaatt ctgatcaaga agtgtctact
    42061 ccttggaaga actatctttt tcacacaggg ttccaggcgt gttcaattat caagatacaa
    42121 aggatcttag ccacccatga aaaataggga atggcactga ctttccacga aaggcaagac
    42181 agacatcttt tttcaagagg caggtagtcc gtgttcaatt gctaagatta actagcctag
    42241 aagtgcctac taaatcactg gaatataacc cagagcaata cttcctgctc ctaggtgcgt
    42301 tccaatgaca ctaccaaatg tagcaagtga aacatccgaa cccaagccaa aatcaagcaa
    42361 atgctgacgc aattcttcag ccttttcagg agcattccca tgaatgacaa tgacccggta
    42421 ttgacctgaa gccgttgttt ccttgataat ttcaattaag cgtttggtgg ccttcttttc
    42481 agtacgaact ttttcgtaaa cttcaatcac accttgatcg ttaaaataaa ggattggctt
    42541 aatgctaagc aaattgccca aaatggcagc cccatttgaa aggcgtccac cttttaccaa
    42601 atgatccaag tcatctacca tgataaaggc tgacgtacgg ctgatttgaa tggctagctt
    42661 atcctgaatg ctggcaaaat catcgccctg atcacgccaa ttaaagacgc tttcaaccat
    42721 gatgcctagg ggagcacttg taatcaaagt gtctgggaaa gcaatggtta agccctcata
    42781 gtcatcgacc atatactgga tattttggta aaaacctgaa attccagaag ataggaaaag
    42841 ccccaaggca tgtgtatagc cttgttcttt gagcgaagtt aagatttcat ctaacttggc
    42901 aatacttggt tgactggtct taggcaattc agaagcctga gccatttttg ggtaaaattc
    42961 ctcagcagac agattgatgc cttcgacata ttcctcacca tcaatattga caggaatatc
    43021 caagacaaac aagtcttctc tttgcaagat ctctgcactg agataagcag aggaatctgt
    43081 gaaaacagct aatttcatat tagaactcca aattaattcc tggtaagtct aatgcaattt
    43141 cagtcacttc gtaagtcaaa cgattgagca tgttcaaaca tggacgagcc aaggtttcca
    43201 cctcttcttg gttcaattca cttggttcat tgacaatacg gccatcgata tggtttactt
    43261 gtgagattgt tccactaatg acaaacttat caaatacaat cataaagctc aagatgacaa
    43321 tcaaggaagt cacttgattt tcttggtcat gttggagcaa ttggaaattc acatccacct
    43381 tggtttcagg agctccattt tcattttccc attcaaaatt acgcgcatca aaatgatact
    43441 gactaacaaa ttcttgttca cgtttaagat tcatgtcttt ctccatcagc tacaatatta
    43501 taagctattg taccataatt ttttattttc atctagtttt ctaggattta gtcaatccca
    43561 atttcagcac gaactacatc tgtgatggta tcaacatagt agtctacttc ttctgttgta
    43621 ggcgcttctg ccataacacg caagaggggt tctgttccac ttggacgaac aaggatacgg
    43681 ccgttccccg ccatttcttc ttccatcttc tcgatgatgg ccttgatagc tggcacttcc
    43741 atggcctttt ccttcatgac gttttccact cggatattaa ctaatttttg tggataaatc
    43801 gttacttctg ccgccaactc tgataagctc ttaccagttt ccttcatgat tttagtcaat
    43861 tgaactgctg ataattgacc atcacctgtg gtattgtaat ccatcaagat aacgtgacca
    43921 gactgttcac caccaaggtt gtaacctgat tttctcattt cttcaacaac gtagcggtca
    43981 ccaactgcag taactgcctt gttaatacct tcgcgattca aggccttgtg gaaaccaagg
    44041 ttagacataa cagttgtcac aattgtattt tgagccaatt gtcctttttc agaaaggtat
    44101 tttccgatga tgtacataat cttgtcacca tcgacgatgt caccattctc atcaacagca
    44161 atcaagcggt cactgtctcc atcaaaggcc aaaccaatag ctgacccact ttctttgacc
    44221 acttcttgaa gggcttctgg atgtgttgaa ccaacattaa ggttgatgtt aagaccgtct
    44281 ggtgtttccc cgataaccgt caattgggca ccaaggtctg caaagatttg acgggcactg
    44341 gtagaagctg ctccattagc tgtatccaag gcaaccttca ttccatcaag aggagttcca
    44401 gttgaaacaa ggtatccttc atacttacgc aagccttctg gataatctac caaaattcct
    44461 aagccttctg cacttggacg aggaagagtg tcttcctcag catctagcaa ggcttcaatt
    44521 tctgcttctt tttcatcatc tagtttgaag ccatcaccac caaagaactt gattccgtta
    44581 tcaagggctg ggttgtggct agcagaaatc atgacaccgg cacttgctcc ttcagtttca
    44641 accaagtaag ctactgctgg tgttgcaagg acaccaagtt tgtatacgtg aatccctact
    44701 gaaaggagac ctgccaccaa ggccgattcc agcatttccc ctgaaatacg tgtgtcacgt
    44761 cctacaaaga ctttcggcgc ttccgtttca tgttgactaa gaacatagcc tccaaaacgt
    44821 cctagtttaa aggctaattc tggtgttagt tctaggttag cttctccacg gactccatca
    44881 gtcccaaaat atttacccat tgttataaaa tccttttcta tttttaattc gtttttgaac
    44941 tagttgcttt cgttgacgaa gatgtctccg atgaactgct tgtacttgaa tttgatgtgc
    45001 ttgaacttgg tgctactggt tttgtagtca ccttcattat tgtatcaaac ggagtgataa
    45061 ctgccggtaa gacaacacca ttgcggtcga ttgcctgcaa aggtactgaa ccactgtaat
    45121 tacctgttat gcgttcgcta gttggcaaga cagcgataat cttatcaatt ctatccaatg
    45181 tctcttggtc actcgtaata gacacttctt tatctgacac catgacattt tcaatttgta
    45241 cccgactatc aatttgacta gggtcaatct ctggtacaat ctttacctta tccttctgag
    45301 ccttcttacc aatcttgact gtaatttttt gcggagtcgc cacagcggtc agcccattgg
    45361 gtaaatcttc aatgctcaaa ggaatttcaa tcgttccaac accggcatct gttaggtcag
    45421 cagtaacctt gaatttacgt gtactttctt gcatttcact agctagcgat aggcgatttg
    45481 caccagtcaa gaccactgat acttctgaag caaaaccgct aataaaatac ttatcactat
    45541 tatagcgtat gtcaataggg acatttgtta ctgtattagt ataggtttcc gtttttacct
    45601 gcctagcact ggtactgttt tgaaaattcg tcgccgtagc atagacaaat aagacacaag
    45661 caaaaaagag tgaggatatg atatataaac tatttttttt catgtttcca tcctcctagc
    45721 aatcgttctt taaaactaag acccacttcc tcttttggaa gtaagatttc acgtaattct
    45781 gtttcaaatt catcaagtgt taggttgtgc ttaaaccttc cattataggt tatcgaaatt
    45841 cctcccgttt cctctgatac gacaaaagtc aaggcatctg agacttctga taaaccgata
    45901 gccgcccggt gtctggtccc aaattccttg gaaatccctg tgttttttgt caagggcaga
    45961 taggcagacg tcacagcgat acgttcttct ttgataatca ccgcaccatc atgtagggga
    46021 gtgttgggaa taaaaatgtt aatgagaagt tctgcagaaa tcttagcatc caagggaatt
    46081 cctgtcgaaa tatactcctg caaggtacgt acacgctgaa tagcaaccaa ggccccgatt
    46141 ttacgaggac tcatgtattc aacagactta acaaaggcac gaatcatctg ttcctcagca
    46201 ctaatagggg cattggaaaa gaaatctgtc gctcttccca aacgttccaa accagtccga
    46261 atctctggag agaagataac aaccgccgca ataaccccat aagtaataat ttgattgatt
    46321 aaccaagaaa tcgtagtcaa accaatcata tttgcaagga tttgagctaa aataaacacc
    46381 aaaactccac gtaccaaaat cataatcttg gttcctgcaa tagcttttgt aaaatggtat
    46441 aaaatataag caacaatcaa aatatcaatc agattgatag ctatcgtcca tggacttgca
    46501 aacaaactgg tccaatattg cagattggat aattgttgaa aattcatccc tgatatcctc
    46561 cctatcaaaa cactttcgtc ctattatacc attttctggc atttttttcc ctatcctagt
    46621 ccattttaca ttgaacaaaa atatgataaa ataaactgac tagaaaaaac aaaggagaaa
    46681 ctatgtctca actctatgat attaccattg tgggtggtgg tcctgtcggg ctttttgcag
    46741 ccttttatgc ccacctacgc caagccaagg ttcaaatcat cgactctctt ccccagctag
    46801 gtggacaacc tgctattctc taccctgaaa aggaaatcct agacgtacca ggcttcccaa
    46861 acctgactgg agaagagttg actaaccgct tgattgaaca gctaaatgga tttgataccc
    46921 ctattcatct caatgaaacg gttcttgaga ttgacaaaca agaagaagaa tttgccatca
    46981 caacttctaa aggaagtcac ctgactaaaa cagttatcat cgctatgggt ggcggtgcct
    47041 tcaaaccacg tccgctggaa cttgaagggg ttgagggcta tgaaaatatc cactaccacg
    47101 tttctaacat tcagcaatac gctggtaaga aagtgacgat tcttggtggg ggagactcgg
    47161 ctgtggattg ggctttggct tttgaaaaaa tcgcaccaac tacccttgtt caccgcagag
    47221 ataatttccg tgccttggaa cacagtgttc aagccttgca agaatcatct gtaaccatca
    47281 agacaccatt cgcccctagc caactccttg gaaatggaaa aacacttgat aaacttgaaa
    47341 tcacaaaagt caaatctgat gaaactgaaa ccattgacct agaccacctc tttgtcaact
    47401 atggtttcaa atcttctgtc ggtaacctta aaaactgggg gctcgacctc aaccgtcaca
    47461 agattatcgt caacagcaaa caggaatcca gccaagcagg tatctatgct atcggtgact
    47521 gctgctacta tgacggaaaa attgatctga ttgcgacagg cctcggagaa gctccaactg
    47581 ctgtcaacaa cgctatcaac tacattgacc ctgaacaaaa agtacaacca aaacactcta
    47641 ctagtttata aaaaagaacc acgagtcaca taggattcgt ggttttataa ttcatccgct
    47701 atcttattga tttttctgag tctgtgattg acaccacttt tggtcagagg ggtgctgaga
    47761 ctatctgcta actgctggat agagtagtct gggtgctgaa tcctcagttg cgccacttcc
    47821 tgcaaatcta ctggcaaatt ttctaagccc atgatatctt tgattttact gatattgtta
    47881 atggtcttca tgctggcaga aactgtccga gcgatattag ctgtctcggc attattagcc
    47941 cgattgaggt cgttacgggt ttctcgcaaa atcttaaccc gctcaaaatc atcacgtgcc
    48001 tgcatggctc ctattactat caagaagtcc ataatgtctt ctgctcgctg gagataggtc
    48061 acagccccct tcttgcgctc aagcaccttg gcatccagta aaaactgttg gagaagggag
    48121 gcaattcctt gcgcgtggtc cagataaaca gaactgattt ccaactggta cttgcctgac
    48181 tcagggtcac gaatgctccc atttgccaag aaagcgccac agagataggc acgacctgct
    48241 tcctcatccg ataaaatcgc ctcatcaata cctgtttcca ggccaaagaa agagtctgcc
    48301 aagtgcaaat cacttaacaa atcctgcacc ttttcatctg taaaaacggt atagacgcga
    48361 ttcttgcgaa gattgctccg ttggtggtga cgaatttcag atttgatttc atagagatgg
    48421 agaaaggact catagaggtg acgggccagt ttggcatttt ctgtcacaac tgacaaagtc
    48481 aagcccgaag tcgagagacc gatgctacca gacattttga taatggcaga taattcatgc
    48541 cagctcagat ggtgttggcc caggatttct tcttttactg ctactgtgaa actcattttt
    48601 tcacctgtat aatgcgcatc aactcgtcca caatcaaatc tccatcgtgg aaggcaccgc
    48661 cattttccag acgaaggaag ttagatgaaa tcacgcgcga aacttgctta caaagaccta
    48721 caaaatcgtg ttccacttgc actaagtatt catcaaaacg gttggaattc atgtattcct
    48781 gaggcacttt ttcaatattc accaagacag tgtcgataaa agggcgacca aggtgacgat
    48841 gcaagacttc cacgtggtcg ctatctgtaa agtgttccgt ctccccacgt tgggtcatga
    48901 tattgcagac ataggcaatt tctgccttgg tttccaaaag agcccgccca atttccttaa
    48961 tcacgatatt gggcaaaata gaggtaaaga gggaacctgg ccctaggaca atcatgtcac
    49021 tttcaaggat ggtctgcact actcgacggc tggccagagg cgtatcatcg tttagggcat
    49081 tggtcacata gacattgtca attatgcctc gatggtctac aatatgactc tctccagcca
    49141 cttctgtccc atcctgaaag actgcatgaa gggtcaaagg atggtcactg gaaggataaa
    49201 ttttccctgt tgtatggaaa aatttgctca ataactgcat ggcattatag gttgaaccct
    49261 gcatttctga caagccagca atgatgagat ttcccaatgg atggccagca aaggctccgg
    49321 catcctcaga gaaccgatac tgaaagacct tctcataaaa cttaggcata tccgacatgg
    49381 ccacaaggac attacgaaga tcacctggcg gtgtcaactg ttgcatattt tttcggagtt
    49441 cacctgaaga accatcatca tctgccaccg tcacgatagc tgcgatttcc acatcttttt
    49501 cccgcagact ttttagaatg acgggaattc cagtccctcc accaatcacc gttatctttg
    49561 gttttctcat gaacggttta ccgtttcctt tctgcggtct ttgtcgcgat gcccttcatt
    49621 aacagaccaa ttcttggata agtcctgcgc caagcgttta gcaaatgcca cactacggtg
    49681 ttgtccaccc gtacatccca tagcaatggt caaaacggac ttaccttcct tttggtaact
    49741 tggcagaatc ggctcaatca aggccaataa atgttgataa aagtcttctg actcaggatg
    49801 gttcatgaca taatcataaa caggttcatc cacacccgtt tggtttctca gttctggtag
    49861 ataataggga tttggcaaga aacggacatc aaagaccaag tccgcatcaa tcgggattcc
    49921 atacttaaat ccgaaagaca tgacttcgat acggaaagac tgggcttgtt cttggtctga
    49981 aaactgctct gcaagggttt tgcgcagttc acgtggagtg agttcagtcg tatccaccac
    50041 attttggctc atatttttca aaggtgccaa gagttcacgt tccaacttga ttccatctaa
    50101 aatacgaccg tctgctgcta gtgggtgact ccgtctggtt tccttgtaac gagcgaccaa
    50161 ttccttatca gccgcatcca aaaagaggat tttgaaatcc aaaccatctt gattttccaa
    50221 ctcatccaaa acagcttgaa tctctgaaaa gaaagaacgg ctacgcatat ccactaccaa
    50281 agccaactta ggattatctt ccttaatttc aaccagctgc aaaaacttag gcaagagagc
    50341 tggcggcata ttatcaatgg tgaaataacc tagatcctcg aaggactgaa tggctacagt
    50401 tttccctgcg ccactcatcc ctgtcacaat caccaagtga agttgtttct ttgtcatctt
    50461 tttctcctta tatcaaaaga agtttggcaa caccaaactt caactagctt atccaatctc
    50521 tgcgatgact tcaatttcga cttttacatc acgaggaaga cgagctacct ccacagctga
    50581 acgagctggg aattcctctt tgaaggccgt ttggtaaacc tcattaaaag gaacaaagtc
    50641 gttcatatcg ctcaagaagc aagttgtttt gacaacatgg tcaaagtctg ttcctgcttc
    50701 tgccaaaata gcaccgatgt ttttcaagac ttgctctgtc tgttcttgga tattctctcc
    50761 tacaatttcc ccagtttcag gggatagggg aacttgaccg ctagcaaaca aaaggttgcc
    50821 aacgattttt ccttgaacat agggtccgat agcctttggg gccttatctg tatgaattgt
    50881 ttttgccatt ttcttttcct cacaattttt ctaagattgc atcccaagcc tcatccatcc
    50941 ctgccttgct gacagatgaa aagaggatga aatcgtcact tgggtcaaag tttaatttct
    51001 ttttgattgc tgattcatgc ttgttccatt taccacgagg aatcttgtcc gccttggtcg
    51061 ccacaatgat gactggaatc tcataatact tgagaaattc gtacatctgc acatcatctg
    51121 ctgacgggtc atgacgaagg tcaactagac tgacaaccgc acggagattt tcccgagtcg
    51181 ttaagtactc ctcaatcatg cacccccact tttcacgttc ctttttagaa acacgagcat
    51241 agccataacc aggcacatcc acaaagcgca tcttgtcatc aatgttaaaa aagttcagga
    51301 gctgggtttt accaggtttt cctgatgtac gggcgagatt cttacggttc aacatagtgt
    51361 tgataaagct ggatttacca acatttgaac gccctgctag ggcaatctct ggcagttcat
    51421 cctgcggata gtgggactta ttagctgcac tgagcaagat ttcagcattg tgtgtattaa
    51481 gttccatagt cacctctagg ctgtttctag gatcggttta tccgttccat cgacagtttc
    51541 tttagtgatg cgaaccaatt tcacattttc ctgactcggc acctcaaaca taacatctag
    51601 catggtttct tcgataatgg agcgaagtcc acgcgcccct gtcttccgtt cgattgcttt
    51661 attagcaatc tcttgaaggg cttcgtcgtc aaattccaac tcaacatcat cataagaaag
    51721 caaggtttgg tactgtttca ccaaggcatt tcttggctct ttcaagatgc gaaccaagtc
    51781 atcaacggtc aattgctcaa gagccgcaaa aacaggcaag cgtccaatca actcagggat
    51841 aataccaaat ttttgaatgt cttcagcgat gatttcttgc atgtatgagc tgttttcgtc
    51901 aatcgcctta ttgttttgac caaatccgat aactttttca cccagacgtt gtttgacaat
    51961 ttcttcaata ccatcaaaag caccacccac gatgaagagg atattttttg tatccacttg
    52021 aatcatctct tgttgtggat gtttgcgtcc accttgaggc ggcacgctag caacagttcc
    52081 ctcaataatc ttgagaaggg cttgttgcac cccttcacca gaaacatcac gtgtgataga
    52141 cacattctca ctcttcttgg caatcttgtc aatttcatcc acatagataa tgccacgctc
    52201 tgcacgttcg atgttaaagt cagcaacctg caagagtttg aggaggatat tttccacgtc
    52261 ctcacccaca taaccagcct ccgtcagagc tgtcgcatcc gcaatagcaa aaggtacatt
    52321 caagctctta gccaaggtct gggcaaggaa agttttccct gaaccagttg ggccaatcat
    52381 caaaatgttt gacttctgca aatccacatc ttctgactct tcgcgtgtat cgtggaaatt
    52441 gatgcgtttg tagtggttat aaaccgccac tgccaaggca cgcttggcac gatcttgacc
    52501 aattacatag tggttcaaga tatggaggag ttcaattggt tttggcacct cagacaagtc
    52561 tgccaagact tcctcaacca attcttctcg aatgatttcc tgagctaact ccacgcattc
    52621 attacaaata aaagcattgt tgccagcaat tattttttgt acttcttctt ggtttttgcc
    52681 acaaaatgag caataaacca tcatatcatt ttttctattt gtagacatga tttccttcca
    52741 ttctatactg tcattctatc taaaataagg tcatgtaaaa agcatgaata ctattgacca
    52801 gattggtaaa ggcatttaac caaaggagga tagaaagccc gtaacgcttt ttacgaaaag
    52861 cctgtgctcc tgccagaaag cagatgaaac acagaaaagc cgtgaataga ccaaataaac
    52921 tccgttccat tagacttcct ttctcttgcg gtattggatg gtaaaatcat aaggattctt
    52981 ctcatctttg gcgtaaaatt tgcttgaaac tgtctcaaaa agagacaagt caagctcttc
    53041 agggaaatag gtatctcctt ccacccgagc atgaatgtga gtgacaatca cttcatcaag
    53101 gtaaggttca aaagcctgaa aaatttgctt cccaccgata atgtagagat tcttttcttg
    53161 agcctgatac cagtcaagaa cagactggac gtcctgaaaa gtagcaaccc catctatctt
    53221 ttcttccgga ttacgcgtca aaatcaaggt ttcccgtttt ggaagcaagc gacgccccat
    53281 cccatcaaag gtcacacgcc ccatcaagat agcatgattc agagttgttt ctttaaagtg
    53341 ctgcaattct gctggcaaat gccaaggcag acgattttcc ttaccaatca caccctcttc
    53401 atcctgggcc caaatagcta cgattttctt agtcatgctt ccatcctttt cactgatagt
    53461 actattttat caaaaaactc aaaaaaagac tggtttggaa tagcttacaa aatagaaaaa
    53521 atctgtaaga aatttcctac agatttatct atgtttcctt atttcttaca aaccaggtgc
    53581 ttgtccaagt tcggctgcaa gcatccaaat tgttttatct gtttcagttt tagcgcctgc
    53641 aaagataccg tttgtcacat cgtcaccttc ttcatcagtg acatccaaac ctttttggaa
    53701 aagttctgac aagtaacggt agataacaag aacacgttcc aagctttctt caacattacg
    53761 gtattcacca gcttcttctt cgatttcact attttgaagg aactctgtca atgtagagaa
    53821 tgggcttcca ccgagtgtaa tcaagcgttc gctgatttca tccaattgac cgtcaagagc
    53881 ttccatgtac tcatccattt ttggatgcca tacaaggaaa ccacgaccat gcatatacca
    53941 gtgcacttgg tgcaaagcaa cgtgagctac atacaaatca gcaacagctt ggttcaagac
    54001 ttcctttgtt tttgccaatg ctactggcgc tgcttttgtc aatgatgtta cgtcttttac
    54061 tgcttctttt ttcaattcta ccattttctt tacctcattc attatttttt gtaaccactt
    54121 cttaatgatt actaccttag tatactacta aggaaaacca atagcaagac aaagaactta
    54181 tatgagaaaa gttgcaatag actgataatt taagaattct ttagaagaca aaaagagggt
    54241 tggatgctta tagtcaatgg aaatccatca gcaaactagg aaactaaacc cagcttgacc
    54301 aaagcacaag ttttgaggtc gcaggtagaa ctgaccaagc tgatgtggtt tgaagaaatt
    54361 ccccaatact ataatagatt gaaataagat gaaaccaagt cgattaggaa aggtaaatga
    54421 atttctaaaa tgttttacca atcacaaggt atttgtctat attcaatcta ctatataagc
    54481 ttcatttccg agcaagatct tgaatttact cgaggatgaa ctatcataaa acaaaaaaaa
    54541 agagggtgct actatcacat ccctctttca aatcattgct taataccaaa cgctgacatc
    54601 tacgcgccct tggattcctt tcatgtattc agaagaggta tattgccaac ctttttctcc
    54661 tgaataataa gggttttccc attctaaagc attcgtatag gccgctaccc agtttacatg
    54721 ttttaaaata tctgggtgtt ttaaacgcgt ctgtaataaa ctacgatagc tatagacata
    54781 cacattttga taacccgcct gcttcatcgt gtccatgtac ttgttgatga ttttaaccca
    54841 agtgcctgta tcacttggag ctctcttgct cttatttaca tattcccagt tctcaacatc
    54901 ataatagata gggtaagaca ggttcatatt gtatttcttt ataagttcaa tggtctgttt
    54961 agcgtcattc tcagcatcgg tctcattttc agcataggta tagagataga caccataagg
    55021 aattcccaga cggtttaact ccttaatgtt atgcgccaat tccttgtctt ctttgccgct
    55081 ataacctaga cgaacaatga caccatccac ctcgttctca tcaataacct ttttccaatc
    55141 attgatacga ccattgtgct cactaatatc aatgattttc ttagcatgtt cggttcccac
    55201 ttgttcttct ctattattaa agaaatagcg tttaccatct ctgtgaaccc agccgacatt
    55261 caaatctttc ttttctttga gctcaccaga ggccgcaaag atatagcgag caccatccat
    55321 aatcacttcg tcagtcgcca tggcaccact tccagtcaaa tagtagttgc cttgccactc
    55381 attccgagcc atatagcccc acttcttgaa atagtaccat ttgccgccca ctttttgcca
    55441 ctcttggtta gcataagttc catcggattt tagataaaaa taagcagaat aagctggatc
    55501 atagagccat tcattttgta tcatagctcc ttgaccattc aagaaataac ttccttgcca
    55561 ttggctttta gccatgtaac cccacttctt gaagtagtac cacttatttc caatcaattg
    55621 ccattcttga tgagcataag ccccatctga cttgagataa aaccaactct tgtaattact
    55681 gtcatagatc cactcgtttt gggccatata tccacctgat ttcaggtagt aatttccatg
    55741 ccattcattc tgcgagtaac gaccatctga attaatataa aaccaagcct tatagtagtt
    55801 gtcaaaaatc cattcacttt gagctttaga accatcatcc tttacataat aatccccatc
    55861 ccagtaggca gcagcattag tctgtacttc tgcgctcgtt tgcgttttat tagaagactg
    55921 attttgctct gaactacttg aagctgtcgt tgtatcctgc gaagtttttg ctacttcagt
    55981 ttcatttgca gcgacatgac tagttgccaa gcctagtaaa cagatacttg ctaatccaat
    56041 ttttattttc aatctttcct ctcctataaa aaatgtaaca gacatctgaa tgctgttcca
    56101 cctagctttt gctacttact gattatttta caaagtcaag caaagccaag aagctttcag
    56161 cttcaagtga cgcaccacct acaagggcac cgtcaacgtc tgggcaagcc atgtatgaag
    56221 caacattttc aggtttaaca gaaccaccgt attgaacacg aactttgtct gcgacttctt
    56281 gaccaaagtc agcagctaca acgtcacgaa caactttaca cattttttgt gcatcgtctt
    56341 gtgaagctga tttaccagta ccgatagccc agattggctc ataagcgata actgaggcag
    56401 caacttgttc agcagtcaat ccagccaatg cagcagatac ttgagcacct acgaattcag
    56461 cagctttacc agcttcgtaa gtttcaagtg attcaccaca acagatgatt ggaagcatac
    56521 cgttcgcaaa gattgctttt gcttttttgt tgatatcttc atcagtttca tggaagtagt
    56581 cacggcgttc tgagtgaccg ataacaacgt agtcagtacc gatttctttc aaaacttgtg
    56641 ggctagtttc accagtgaaa gcacctgcat tttcaaagta gcagttttga gcagcaactt
    56701 taaggtttga gccttttgca acagcaagaa cagttgtcaa atcaagagct ggagcagcga
    56761 tacctgcttc aacaagatct gatgaaggaa gttttgatgc aactgcttca acgaatgctt
    56821 tagcttcttc tggatttttg ttcattttcc agttaccagc gataaatggt ttacgtgaca
    56881 tttcacatac ctcttttttc aatttatttt ctattttatt ctatcacaat tatacacagc
    56941 ttgcaaatct tactcggatt tcaagcctgc ttgcatggat taatccttcc agagatccat
    57001 ggcatttctg aaatctgcag atacctgtgt caactgagga ttgcttgctt ctctttctgc
    57061 tctcttggcc tcaatttgag ccacactctt gattccttca tggcgccagt ttctcaaaat
    57121 cgcctgaatg tacttccagt ttggttttcc attcaaaaca gcttcacgaa gagcctcctt
    57181 aatcaagtca gcactggttc catcttcctt tagtgtcttg gtcaaatcct caatctcaaa
    57241 aggcgtcaac aatcgtccca actcctgctg gaaggtttcc accaaatcct tgagctggtt
    57301 ttgaggtgtt agctggtctg aacttgaacg aactgctcca aacaggtcat ccaaacgttc
    57361 caaggccaaa ctagcatcaa agaacaattc aatttcgcca tttaattcga tagtacgata
    57421 ctggagcagt cccctttccg tcagattaga aatggactgg ttgacatccg aaatttcctt
    57481 gccaatcctt tcagcaatct ggcttggcga catttcttct aagcctgtcg tattttgcaa
    57541 atagaaaaat tgccaaacca gaaaatcgtc gctagaagga aagagttcct taaaatgcaa
    57601 gagcagggca ctcggtaaaa ccaaggtacc tgatttaaaa gcgtctaaat atgtcataat
    57661 tcctcttata aatacccata tgcagatgca tcatcttcta tctttctcca atcaaaaggc
    57721 gtctcctgat agaccgcatg gtttacccaa ttactgaaaa agagggctgc agatgaagac
    57781 caacaaagac aaggtacctg attaacatca tcatctttaa agtaattttc tggaatatgt
    57841 gggtcgaaac ctgcatcacg atctcgaaaa tactcttttg ccaaggtatc acggtcatac
    57901 tccaaatgac caaaactata aatttctcgt aaatcacgac tggccaaaat agaaacccca
    57961 acctgaggtc cttctgataa aatctcgaga ttggtcttgt ttaagacctc ttccttagaa
    58021 atctccgtgt gccgtgaatg aggggataca tagctatcat caaagcctct aaatagaagg
    58081 tgaccctctt ttagggtgtc ctgaggataa atacctgata gcttactgtc catctggtat
    58141 ttttctacac catagcgcag ataaagccca gcctgagccc cccaacagat atgaagggtc
    58201 gaatagacat gagtcttaga ccactcaagc atctgtctaa attcctccca atagtccact
    58261 tcctcaaatg gtaaatgctc aactggagca cccgtgatga tcatcccatc aaaatactca
    58321 tccttgactt caggaaaagt tttatagaag gtctccatgt gctctgaacg agttgtttta
    58381 gaacggtggc tctccatata gagaaaatca atatccagtt gtaggggtgt attagccaag
    58441 tggcgcaaca actgggtctc tgtgaccatt ttctgtggca tgagatttaa aattaaaatc
    58501 ttcaaaggac ggatatcttg gtgggcagca cgttgatcat ccatgacaaa gatattctct
    58561 gtccgtaaaa tctcaacagc tggcaatttt ttatcaattc gaatcggcat aaccctctcc
    58621 taactgtact ctttcaggaa taattgcata tgtttgaaga caaatctcaa acacttagtc
    58681 cttttattat actgcaagaa gatatagttt tcaattatag tttttctcta actagttata
    58741 gtctattttt atatcctagt gtagagaaaa cagccctggg gactgttttc attaataatg
    58801 cataagaact ttgtagtcgt agtcaccgat tttttcacgg ccgttcaatt catccaattc
    58861 aacaaggaag gcacaacctg ccataacacc accaagtttt tcaatcatct cgatagttgc
    58921 cttaacagtt ccacctgtcg ccaaaaggtc atctacaata agaacacgtt gacctggctt
    58981 aatggcatcc gcgtgcatag tcaaggtatc gacaccgtac tctttttcat agtcagcaga
    59041 aataacttcg cgtggcaatt tacctggctt acgaacaggc gcaaaaccaa ttcccaactc
    59101 aaaggcaact ggacaaccca cgataaatcc acgagcttca ggtcccacga tcatgtcgac
    59161 tttcttgtca gtagcatact gaacgatttc acgaacagcg tagctataag catttccatc
    59221 agccatcaaa ggactaatat cacggaaggt aatgccttcc tttggataat tttcaattgt
    59281 tgcaatgtaa tcttttaaat tcatcttttt ctttctttca aagtttttta ctctctatta
    59341 tagcatattt tttaagaaag aaaaaaggaa aagttaactt caataattat ctaacgtttt
    59401 gacgatttat aactagccat cgcaataaag cccaatttct gtttattctt agcaaacatt
    59461 ttatacatag ttaaaaactg ctttctattc tcctttttac aagcatttac acaaattttc
    59521 aaagttccta gcaaaccttc gtcataaatc atacccgata atttcattaa tgtcatttca
    59581 ccagtcaatg ctttcacatc acaataacct gattctatca tcacctgttc ccaaccatct
    59641 tgagttaaag gacctacatt tacatgaatt gcttgtgata attcctgtct gatagactct
    59701 ttagcttcct taagaagcac atcatgtgtc aagagaagac ctccaggttt taataccctt
    59761 agatattcca ttacacattt tttcttagct tgatcggctt gcatagtcag catagcttca
    59821 tttataacaa tatcaaaact agcatcttga taaggaagtt tcattgcatt tgctctttca
    59881 aaactgatta aatgagcaac acctgccgtt ccagcagatt ttttagccac ttctaaagct
    59941 tgagcatcca tatcaacagc agttatcttg caaccaaaac gctgtgccaa ctcaattgct
    60001 gtagttcccc tattacacgc aacctctagt attctctttt cttttgaaaa tcctccttct
    60061 gcaattaacc aatctgtggc acgctttcca cctggacgta agcgtttttt ccccaatttt
    60121 gctaaaaact tatgacctgc ttctgacatt tgcacacctc tgttttttct tcattataac
    60181 acaaaatgat attatctgac aattctaatc tattatttga taaactagaa tcaaaagcat
    60241 acaagtcacc ataactatag cataaattta ttattacctc tctagttcga attcaattac
    60301 tcacgtagtt tacgcatata gcttcacttg tagatggtac ccacaaataa tactcaatgg
    60361 aaatcaaaga gcaaactagg aaactagccg taagctgctc aaagtacagc tttgaggttg
    60421 cagataaaac tgacgaagtc agtaatcata cgtacggcaa ggcgacgttg acgtggtttg
    60481 aagagatttt cgaagagtat taaagagcat cacaatatag atgcataata tgacttccct
    60541 agcaaaaagg agagaagcat tttgtttctc tccctagatt aactgatatc tctccactac
    60601 aattgataaa gagatatctt ttcttgtagt gctttgaatt ttatttattt tagtagattg
    60661 ttttttcagt ttctacatcg aagaagtgtg ctttgttcaa gtcaaatcca agctcaactg
    60721 ttgcacctgt ttgcaagtag tcacgagcat caacttttgc aacaaactcg tctttaccaa
    60781 cttggcagta aaggtgagat tctgaaccaa gcagttctga tacagagata gtcgctttta
    60841 caacacagtc tgggaatgtt tcaaggaaag caggttctgc attcacgtct tctggacgga
    60901 taccaaagat caattctttt ccttcgtagc ctttttcacg aagaactttc aatgctcctt
    60961 ctggcacttt caaacggaaa ccgtcagaaa caatttcgct accaaccaat ttcacgttga
    61021 tgaagttcat agctgggctt ccgatgaatc ctgcaacgaa tttgttaact ggatttttgt
    61081 aaacttcttg aggagtaccg atttgttcta cacgtccgat agtacctgta ccagcagggt
    61141 tcttagtagc tgacataata acgatacggt ctgcaagtgt catcgcttct gtttggtcgt
    61201 gagttacata gatagttgta gctccgatac gacggtgaat tttagcgatt tcagcacgca
    61261 ttgatacacg aagtttggca tccaagtttg acaaaggttc gtccatcaag aatactttcg
    61321 catcacggac aatcgcacgc cccatggcaa cacgttgacg ttgaccacct gaaaggtcag
    61381 ctggtttacg ttccaagaat tctttcaatc caagtatttc agctgcttct tgaacacgtt
    61441 tgttaatgtc ttctttgctg tatttacgca atttcaaacc gaaagccatg ttgtcataaa
    61501 cagtcatgtg tgggtaaaga gcgtagtttt ggaataccat ggcgatatca cggtcttttg
    61561 gagctacgtc gttgacaacc acgccatcga tagatgcagt accttctgtg atgtcttcaa
    61621 gaccagcaat catacggagt gtagttgatt taccacatcc tgaaggtcct acgaaaacaa
    61681 taaattcttt atctttgatg ttcaagttga aatcttcaac tgaatagtgt tcgctgtttg
    61741 gatatttttt gtaaatattt ttaagattca attctaccat gaggtgaact ccttttgtct
    61801 tttgataatt atattataaa tgaaaacgct ttatatttct atggcaagat gaccaaaaaa
    61861 ataaacaagt tctgtgcaac ttgcacaaaa ctttagagaa tatcggagaa tttgaagaag
    61921 ataatcttta ttattcttct atagacaaaa gcagaaacaa ggatcagttt tcccatattt
    61981 tcgctgattc tccactacat ttgactggat tctaattttt tagagaaata caaaagagct
    62041 agctttagct agctcttttc ctatgcggag agagggactt gaaccctcac gacctaaagc
    62101 ggtcacagga tccttagtcc tgcgcgtctg ccaattccgc catccccgcg tcgattactt
    62161 tactagtata tcaacttttg ggatgcttgt caacactttt tttcaaattt tttcattttc
    62221 accaaccagg ttactcagaa agttcattta gattttcatc tactaactta gctccgagtg
    62281 tatttttgaa atgacctagg gcaaattgat gattttcagg ccagatggaa gcaacagctg
    62341 gtttaacaat ctcgatgtca tatcctagat tataggcatc tatagctgta tgtaggacac
    62401 agatatccgt caagacacct gttaagataa cggtagacac tctacgctct ctcaaacgaa
    62461 tatctaggtc agtccctgaa aaagctgagt aatggcgttt atccatccaa aagacacgac
    62521 tgtctgaacc atgctcttga taaaagatcc ccaaatctcc atataaattc cgtccactcg
    62581 tcccaatcag attatgagga ggaaataact tactttccgg atggaaacaa tcgttttctt
    62641 catgagcatc aatagtaaag aagatataat ctcctcgttc aaaagctaat cgagttacct
    62701 tgctgatggc atccgaaatc gcctgagctg gagcacctgc tgttagtttc ccactatcag
    62761 caacaaaatc ttctgtataa tcaatcgaaa ttaaagcctt tgtcattagt aatctctttt
    62821 cttcacttct tcaaaaatat ctgaaatcaa gaccttaaga taggttccct tcattccaag
    62881 tgagcgactt tcaataatcc ccgcagactc aagtttacga agagcattga caatcacaga
    62941 gcgagtgatt ccgatacgat ctgcaatcac tgacgcagtc aacttccctt catttccatt
    63001 taattcccct aaaattgctg aaacagcacg gagttcggag taagaaaggg tattgaccgc
    63061 catggtgaca gcagtacgac gacgaatatt tttctcatct tcttcacgtt ggaagttaag
    63121 aagctgaatc ccaacaacgg tactggcaat ctcaacaaga accaagtcct catcttcgaa
    63181 ttttttatca ttacgccaaa taatcaaaga accaaggcga atccccgata catgaatcgg
    63241 tgcaatagtc gtcaagccat ctggaaaatc atctctactc tcaacaggga aaatactcat
    63301 atcatgctca acaggcaagt ttgcttctgt ttcgtaaatc atattagccc cttgaacgta
    63361 gtcatctggg aaaatcttag tttggaagaa ttgctctacg cgatctgtat ttgttttata
    63421 acgcataaaa tagccaagca gacgtccctt actattgata atgcaggcat tgcaatgaat
    63481 aatatccgct aactgacgcg taatagcgtt gtaaggaagc tcatcctgca actgctcctc
    63541 tgagcgtttc aaaattgatg taatttttct agttttttct aataaatgtg ccatttttca
    63601 cctcgaattt aatcgctatc attataacat aaaaacgtct ctttttcaat aattatctga
    63661 aaattcctta ttgacttgca ttgacttaca atttaattaa aaaccagaat atttttaatt
    63721 aaattgttcc ttttctattg acaagttgcc tatttttgtg tatcataata ttataaaaga
    63781 taatataata attttatttg tctttttcac attcggtctc cttatataaa aaagcgattc
    63841 attttgaacc gctttttctt atttatcacc tttgttacga ataacaaagc ctgtttgctt
    63901 ttcgcttaaa gtattgcgtg gttttttatt atccttacgg taacgttttt ccttatcaaa
    63961 acgatcgttg ccacgacttc cttttttgaa ctcatcacgg cgaccattgc cacggcgatc
    64021 acgctctcga cggtcgtccc cacgacggcc tccacgacct cccttagctt taccaccgaa
    64081 accattacct gatggtttaa acggtagtgg tttttcacgt gcaatctcca cttctggaag
    64141 gctatctggg tcttggactg tcagactcaa gatatacatt gccaattctt ctggagtaaa
    64201 ctcagcagcc aatttgcgag catccttacc aaatttctca aagttggcac gaatggtttc
    64261 atctgcaaaa tcacgttcga ttttcttgag agctacctgt ttttttgatt ggaaggattc
    64321 ttctacactt gcaggtttga gacctttcat gcgtttctta gtcaagtttt caatgatttg
    64381 aaggtaaccc atttcgtttg gagcaacaaa agtaatagat tgacctgact taccagcacg
    64441 acctgtacga ccgatacggt gaacataact ctcaggatct tgtggaatat cgtagttgta
    64501 gacatgggtc acacctgaaa tatccaaacc acgcgctgca acgtctgtcg caaccaaaac
    64561 atcaagattg ccatttttaa agtcacgaag gacacgaaga cgtttgtttt ggtctaggtc
    64621 gccatgaatt ccttctgcac ggaagccacg aattttcaaa ccacgagtca attcatccac
    64681 acggcgtttg gtacgaccaa atacaatagc gagttctggt tgtgccacat ccatgagacg
    64741 agtcatggtg tcaaattttt cttgttcctt aacacggata tagtactggt caaccaattc
    64801 tgttgtcaat tccttagccg caatcttgac atgttcaggg gctttcataa actgaacacc
    64861 gatacgtttg atggcatctg gcatagttgc tgagaaaagc aaagtttgac ggttctcagg
    64921 tacacgggaa ataatggctt cgatgtcttc aaggaagccc atgttaagca tttcatccgc
    64981 ttcgtcaagg ataagggttt caatgttttg taatttcaag gccttgcgtt taatcaagtc
    65041 caagaggcga cctggagttc ccaccacgat atgggcacca gatttaagag ccttaatttg
    65101 tttttcaatg cttgatccgc catatactga acggactttg actcccttac tacgaccaaa
    65161 gcggaagagt tcttcttgac tttggacagc tagttcacga gttggagcga tgaccaaggc
    65221 ttgaatagtc gcttcttctg tacggatttt ttcaagggta ggcaagccaa aggctgcagt
    65281 ttttcctgta ccagtctgag cttgaccgat aacatccttg ccttcaaggg ccaaaggaat
    65341 agtttgttct tggataggac tagcttctac aaaaccagct ttttcaattt ctgccagcaa
    65401 atcagcagac aagtttaatt cattaaattt cacgttattc ttctttctaa aggtggtgcg
    65461 aagccaccct atagggctta gtttatactt ttctttttat gacgtatttt catataacta
    65521 gatataaaat cgtgttgctt cttttccaca aaagaaaagt actgttttct ttgcaaccta
    65581 tctagtataa cataagacca gagcaaaaga tagccccatt tctacagaaa atcatgtaag
    65641 cggtttttga ctttcttttt tgattgaacg acctagataa taagacaaag ccaaggcgat
    65701 actgtataaa atgagaaaaa cgaacaaggt ttgtgtgtac gaatgagcca ttttataagt
    65761 ctctgctaat aaaataggtc ccgctaaacc agccattgcc caagctgtta aaatataacc
    65821 atgcagagcg gccaattcct tggttccaaa aatatcactg agataagctg gaatcaaaga
    65881 aaaaccagct ccatagcaag tcatcaaaat agacatagcg actacaaata aaacggaatc
    65941 tgtaaagagc caaagtgaga gagaaaagaa aagattaaca agcagtaata tactaaaggt
    66001 tagagggcga ccgatatagt cagataagct cgcccagagc aagcgaccaa atccattgaa
    66061 aatccctaaa acgcccacca ttactgctgc atgacttgta gacaagccag ccatctcctg
    66121 tgccattggc gatgccgctg aaattaagcc taaaccacaa gctatgttga taaagaaaat
    66181 aatccaaagt atataaaacc gattgctttt tagagcctga tttgcagtca tcccttgcgt
    66241 cagagagtct gttttttctt tccctgaagc agataaaatt gcaagctctt gctcatttgg
    66301 acgcttaatg aattgtgaag ctaggagcat gataataaag taacttgcac ctaaaatata
    66361 aaaagtttct acaagcccta cccctgcgat gagatgttgc gctatgggac tagtcaataa
    66421 agaagcaaaa ccaaacccca taatcgctaa acctgttgcg agaccacgtt tatcaggaaa
    66481 ccattttata atcgttgaca caggggtaat atagcctgct cccaaaccaa gcccacctaa
    66541 aatgccataa gctagataca acaaccacag ttcctgacgg tctattgcaa atcctgttaa
    66601 gatatttcca cctgcgtata gaaaagcaga tagactcccc atgactctcg gaccaaattt
    66661 ttctaccaaa cgccccataa atgcagccga taagcccaaa caaaagattg ctagactaaa
    66721 ggcaaaggca acagaagcct gatcccatcc cgttttttca ataatagggt tacgataaac
    66781 actccaagca taagtcgaac ccagcattaa gtgtaaaatg accccagcaa aggcaataat
    66841 ataacgattc gatttcataa aacctcctat tttcgaacat tttttctatc ttatataaaa
    66901 atagatagga ttttagttta tcaagcttgt caaaaaatta ctagtttttt gtctggaaag
    66961 cgtttttatc tttttctgtc ttttccgtag cagaattgtg caaaagtttt tttcttgtgc
    67021 tagaatgaaa tgcgaatagg aggaactcta aatgttaact tatgatttaa tcgttatcgg
    67081 atttggtaaa gctggtaaaa cactagcagg taaattggct tcagctggca aaaaagttgc
    67141 cctcgttgaa cgtagcaaag ctatgtacgg tggaacttgt atcaacatcg gttgtatccc
    67201 aactaaaact ttgctggttg ctgctgagaa agacttgtct tttgaagaag tcattgctac
    67261 caaaaacacg atcactggtc gcctcaacgg taaaaactat acgactgttg ctggtactgg
    67321 cgtcaatatc tttgatgctg aagctcactt cctttcaaat aaagtcatcg aaatccaagc
    67381 tggtgatgaa aaacaagaat tgactgctga aactatcgtc atcaacactg gtgctgtttc
    67441 aaacgtcttg ccaatccctg gacttgctac aagcaaaaac gtctttgact caacaggtat
    67501 ccaaagcttg gataaattgc ctgaaaaact tggagtcctt ggtggcggaa atatcggtct
    67561 tgaatttgct ggcctttaca ataaactagg aagcaaggtt acagtcctag atgccttgga
    67621 tacattccta cctcgtgcag aaccttccat cgcagctctt gctaaacaat acatggaaga
    67681 agacggtatt gaattgcttc aaaatatcca tactactgaa attaaaaacg acggtgacca
    67741 agtgcttgtc gtaactgaag acgaaactta ccgtttcgac gcccttctct acgcaactgg
    67801 acgcaaacca aatgtagaac cacttcaact tgaaaataca gatattgaac taactgaacg
    67861 tggcgctatt aaagtagata aacactgtca aacaaacgtt cctggtgtct ttgcagttgg
    67921 agatgtcaac ggtggtcttc aatttactta catttcactt gatgacttcc gtgttgttta
    67981 cagctacctt gctggagatg gcagctacac acttgaggac cgtctcaatg tgccaaatac
    68041 tatgttcatc acacctgcac tttcacaagt tggtttgact gaaagccaag cagctgattt
    68101 gaaacttcca tacgcagtga aagaaatccc tgttgcagcc atgcctcgtg gtcacgtaaa
    68161 tggagacctt cgcggagctt tcaaagctgt tgttaatact gaaacaaaag aaattcttgg
    68221 tgcaagcatc ttctcagaag gttctcaaga aatcatcaac atcattactg ttgctatgga
    68281 caacaagatt ccttacactt acttcacaaa acaaatcttc actcacccaa ccttggctga
    68341 gaacttgaat gacttgtttg cgatttaagt tgaaatctca tcttaactga cagccctctt
    68401 tgggctgttt ttacttctac gaaacaccaa atctgtcttt tccctctttt gtgatataat
    68461 agaaacatga acttaaaaac tactttgggc cttcttgctg ggcgttcttc ccacttcgtt
    68521 ttaagccgtc ttggacgtgg aagtacgctc ccaggtaaag tcgcccttca atttgataaa
    68581 gatattttac aaaacctagc taagaactac gagatggtcg ttgtcactgg aacaaatgga
    68641 aaaaccctga caactgccct cactgtcggc attttaaaag aggtttatgg tcaagttcta
    68701 accaacccaa gcggtgccaa catgattaca gggattgcaa caaccttcct aacagccaaa
    68761 tcttctaaaa ctggaaaaaa tattgccgtc ctcgaaattg acgaagccag tctatctcgt
    68821 atctgtgact atatccagcc tagtcttttt gtcattacta atatcttccg tgaccagatg
    68881 gaccgtttcg gtgaaatcta tactacctat aacatgatat tggatgccat tcggaaagtt
    68941 ccaactgcta ctgttctcct taacggagac agtccacttt tctacaagcc aactattcca
    69001 aaccctatag agtattttgg ttttgacttg gaaaaaggac cagcccaact ggctcactac
    69061 aataccgaag ggattctctg tcctgactgc caaggcatcc tcaaatatga gcataatacc
    69121 tatgcaaact tgggtgccta tatctgtgaa ggttgtggat gtaaacgtcc tgatctcgac
    69181 tatcgtttga caaaattggt tgagttgacc aacaatcgct ctcgctttgt catagacggc
    69241 caagaatacg gtatccaaat cggcgggctc tataatatat ataacgccct agctgctgtg
    69301 gccatcgccc gtttcctagg tgccgattcg caactcatca aacagggatt tgacaagagc
    69361 cgtgctgtct ttggacgcca agaaaccttt catatcggtg acaaggaatg tacccttgtc
    69421 ttgattaaaa atccagtcgg tgcaacccaa gctatcgaaa tgatcaaact agcaccttat
    69481 ccatttagcc tatctgtcct ccttaatgcc aactatgcag atggaattga cactagctgg
    69541 atctgggatg cagactttga gcaaatcact gacatggaca ttcctgaaat caacgctggc
    69601 ggtgttcgtc attctgaaat cgctcgtcgc ctccgagtga ctggctatcc agctgagaaa
    69661 atcactgaaa cgagtaatct ggagcaagtt ctcaagacca ttgagaatca agactgcaag
    69721 catgcctata ttctggcaac ttatactgcc atgctggaat ttcgtgaact gctggctagt
    69781 cgtcagattg ttagaaagga gatgaactaa tggtttatac ttcactttcc tcaaaagatg
    69841 gcaattaccc ctatcagctc aacattgccc acctctacgg aaatctcatg aatacctacg
    69901 gggacaatgg aaacatcctc atgctcaagt atgtggctga aaaactggga gcccatgtga
    69961 ccgttgacat cgtttctctc catgatgact ttgatgaaaa tcactacgac atcgcctttt
    70021 tcggtggtgg tcaagacttt gaacaaagta tcattgcaga cgacctacct gctaaaaaag
    70081 agagcattga caactacatc caaaacgacg gtgtagttct ggctatctgc ggtggtttcc
    70141 aactattggg tcaatattat gttgaagctt caggaaaacg tatcgaaggg ctaggggtca
    70201 tgggacacta cacgctcaac cagaccaata accgttttat cggtgacatc aagattcaca
    70261 atgaagattt cgatgaaacc tactatggat ttgaaaatca ccaaggccgt accttcctct
    70321 ctgatgacca aaaaccgctg ggacaggttg tctatggaaa tggaaacaac gaagaaaagg
    70381 tcggtgaagg ggttcattat aagaatgtct ttggttccta cttccacggg cctatcctct
    70441 ctcgtaatgc caatctggct tatcgcctag ttactactgc cctcaagaag aaatatggtc
    70501 aggatatcca actccctgcc tatgaggata tcctcagcca agaaatcgct gaagagtaca
    70561 gtgacgtcaa aagcaaggct gacttttctt aaacaaagga aaatgatatc aaagaactcc
    70621 gttatcttgt cggagttttt tgtcttttct tttacccttc tcccttgcat tttctctcat
    70681 tttttgccaa aatagagggg tagaaagaag gtagcatatg tctaaattac aacaaatcct
    70741 aacatatctt gaatcagaaa aactagacgt cgctgtcgta tctgaccccg tcacaatcaa
    70801 ttacctcact ggtttttaca gtgatcccca tgaacgccaa atgttcctct ttgtcctagc
    70861 ggatcaggaa cctctcctct ttgtcccagc tcttgaagta gaacgtgcaa gtagcaccgt
    70921 ttccttccca gtagtgggct atgtcgattc tgaaaatcca tggcaaaaaa tcaaacatgc
    70981 tcttccacaa cttgacttca aacgtgtcgc tgttgagttt gacaatctca tcttgaccaa
    71041 ataccatggt ttgaaaacaa tttttgaaac tgctgagttt gaaaacctca ctcctcgtat
    71101 ccaacgcatg cgcctcatca aatcagctga tgaagtacaa aaaatgatgg ttgcaggtct
    71161 ttatgctgac aaggctgttc atgttggttt tgacaatatt tctcttgata agactgagac
    71221 agatatcatc gcacaaattg actttgccat gaaacgtgaa ggttacgaaa tgagctttga
    71281 taccatggtc ttgactggtg ataatgctgc gaatccacac ggcattccag cagctaataa
    71341 ggttgaaaat gatgctcttc tcctctttga cctgggggtt ctggtcaatg gctatgcgtc
    71401 agatatgact cgtacagtcg ctgtcggcaa accagaccaa ttcaagaaag atatttacaa
    71461 cttgactctt gaagcccaac aagctgctct tgactttatc aagccaggtg tgactgctca
    71521 tgaagtggac cgcgctgccc gtgagatcat cgaaaaagct ggttatggtg agtacttcaa
    71581 ccaccgtctc gggcatggta tcggtatgga tgtccatgaa ttcccatcta tcatggaagg
    71641 aaacgacatg gtcatcgaag aaggcatgtg cttctctgtt gaaccaggta tctatatccc
    71701 tggtaaagtc ggtgttcgta ttgaagactg cggtgttgtt accaaggatg gcttcgacct
    71761 ctttacaagc accagcaaag atttgcttta ttttgattaa actatatagc ccctatgctt
    71821 tcctttcaaa atatctaggg gctattttat tgtcattttt ctgctattat gctaaagaaa
    71881 ttggctgcaa taatctaacc ctaagtgtct ggaatgataa cgagggtgct ctccgctttt
    71941 atcaaagaca agggatgaaa ccccaagaaa caacaatgga aatgataatt gattaagaag
    72001 tcatctatca aaagatgtta gaaaaagttc aatttcacta gaaaatgagg aaaatcttcc
    72061 cacaataaaa cgcatattat caagtgttaa aatgtaccgc cccccaaaag ttagacaatt
    72121 aatttatcca aaggatttag ttctgtactg cacaggacta agtcctttta gttttacctt
    72181 aattcgttta ttgttgtagt aatcaatata gtctacaata gcttgttcca attgattaag
    72241 tgatttaaat gttttctcat agccataaat ttcagaatcc caaagaagga ctccatcata
    72301 ccgttgtctt ggctgtttcc cttgcgtgac atggatgctt gaattccctt actctctaag
    72361 aaccgatgat aagaatcgtg ttgatattgc cagccttggt cactatggag aatcgtattc
    72421 tcgtagtact tctctgtgaa tgcctgttcc aacattgttt gtacttgttc taagttgggt
    72481 gaagttgaaa gattataggc gataatttcg ctgttaaaac catctaaaac tggtgataag
    72541 taaagctttt gagtacttgc tggaatggca aattctgtca tatctgtgta gcacttttcc
    72601 attgttttag agccttcaaa ttggccttga atgagattct ctgccttctt accaacgtct
    72661 cctttatgag aagaatattt tcgtttctgt cgcattttag tttgtaaatt gagtactttc
    72721 atcaagcctt gaactctttt atgatttacc agataagcac gatttcttag ttctaaatga
    72781 acccggcgat aagcataatt tcccttgtgt tcgataaaaa tggattgaat ttcagcttta
    72841 agctcttggt ccttatctgg tttgtctagc tgtttcaagt gatagtagta ggtcgaacga
    72901 gctagtttaa tggcttttag aagaagatct aacgaaaact cagtcattaa ttcttgaaca
    72961 atttctgtct ttcttctttc tctttttcct cct
//
LOCUS       DBERPV010000008        64335 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.08, whole genome shotgun sequence.
ACCESSION   DBERPV010000008 DBERPV010000000
VERSION     DBERPV010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 64335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64335
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.08"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(149..496)
                     /locus_tag="ACL8C7_000694"
     CDS             complement(149..496)
                     /locus_tag="ACL8C7_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGS1394945.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(607..2382)
                     /gene="spxB"
                     /locus_tag="ACL8C7_000695"
     CDS             complement(607..2382)
                     /gene="spxB"
                     /locus_tag="ACL8C7_000695"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HGS1394946.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAISKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNDEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(2589..4832)
                     /locus_tag="ACL8C7_000696"
     CDS             complement(2589..4832)
                     /locus_tag="ACL8C7_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGS1394947.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSVTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDVIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQTLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QAAGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(4842..5213)
                     /locus_tag="ACL8C7_000697"
     CDS             complement(4842..5213)
                     /locus_tag="ACL8C7_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HGS1394948.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            complement(5224..5619)
                     /locus_tag="ACL8C7_000698"
     CDS             complement(5224..5619)
                     /locus_tag="ACL8C7_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HGS1394949.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKFFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      5803..5901
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            5985..6776
                     /gene="thiD"
                     /locus_tag="ACL8C7_000699"
     CDS             5985..6776
                     /gene="thiD"
                     /locus_tag="ACL8C7_000699"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HGS1394950.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFIKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(6985..7617)
                     /gene="thiE"
                     /locus_tag="ACL8C7_000700"
     CDS             complement(6985..7617)
                     /gene="thiE"
                     /locus_tag="ACL8C7_000700"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HGS1394951.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(7610..8413)
                     /locus_tag="ACL8C7_000701"
     CDS             complement(7610..8413)
                     /locus_tag="ACL8C7_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HGS1394952.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVIKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLVVSKNQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEAYE"
     gene            complement(8413..8937)
                     /gene="thiW"
                     /locus_tag="ACL8C7_000702"
     CDS             complement(8413..8937)
                     /gene="thiW"
                     /locus_tag="ACL8C7_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HGS1394953.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            complement(8942..9634)
                     /gene="tenA"
                     /locus_tag="ACL8C7_000703"
     CDS             complement(8942..9634)
                     /gene="tenA"
                     /locus_tag="ACL8C7_000703"
                     /EC_number="3.5.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050334 - thiaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HGS1394954.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(9645..10295)
                     /locus_tag="ACL8C7_000704"
     CDS             complement(9645..10295)
                     /locus_tag="ACL8C7_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T"
                     /protein_id="HGS1394955.1"
                     /translation="MVKVATQPPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQKLHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(10297..11682)
                     /locus_tag="ACL8C7_000705"
     CDS             complement(10297..11682)
                     /locus_tag="ACL8C7_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS1394956.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIVERVQTVGILLQNPNHQFTMESLFEELVFTMENI
                     GYHLQEIDSKIAEVVQQCRCKDILHRLIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELVYDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGSITWKGSVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(11683..12243)
                     /locus_tag="ACL8C7_000706"
     CDS             complement(11683..12243)
                     /locus_tag="ACL8C7_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGS1394957.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGFVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(12505..12593)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(12802..13431)
                     /gene="thiE"
                     /locus_tag="ACL8C7_000707"
     CDS             complement(12802..13431)
                     /gene="thiE"
                     /locus_tag="ACL8C7_000707"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HGS1394958.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFGTQSKNDAGGTIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(13433..14215)
                     /gene="thiM"
                     /locus_tag="ACL8C7_000708"
     CDS             complement(13433..14215)
                     /gene="thiM"
                     /locus_tag="ACL8C7_000708"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004417 - hydroxyethylthiazole kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HGS1394959.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVMIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            complement(14458..15126)
                     /locus_tag="ACL8C7_000709"
     CDS             complement(14458..15126)
                     /locus_tag="ACL8C7_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HGS1394960.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVDKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     regulatory      complement(15341..15429)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(15683..16819)
                     /gene="lctO"
                     /locus_tag="ACL8C7_000710"
     CDS             complement(15683..16819)
                     /gene="lctO"
                     /locus_tag="ACL8C7_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HGS1394961.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCNVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(17443..18933)
                     /gene="lysS"
                     /locus_tag="ACL8C7_000711"
     CDS             complement(17443..18933)
                     /gene="lysS"
                     /locus_tag="ACL8C7_000711"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HGS1394962.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLITKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINKPFKRVHMVDAIKEITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(19073..19207)
                     /locus_tag="ACL8C7_000712"
                     /pseudo
     CDS             complement(19073..19207)
                     /locus_tag="ACL8C7_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            19423..20103
                     /locus_tag="ACL8C7_000713"
     CDS             19423..20103
                     /locus_tag="ACL8C7_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS1394963.1"
                     /translation="MDWSIVEQYLPLYQKAFFLTLHIAVWRILGSFLLGLIVSIIRHY
                     RIPVLAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMA
                     ESFRSGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVELPSFSANVIFLIKETSV
                     FSAVALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRFRHAGFG
                     NPSTLSGK"
     gene            20063..20740
                     /locus_tag="ACL8C7_000714"
     CDS             20063..20740
                     /locus_tag="ACL8C7_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS1394964.1"
                     /translation="MQDSEIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTH
                     LEKHWRN"
     gene            20741..21499
                     /locus_tag="ACL8C7_000715"
     CDS             20741..21499
                     /locus_tag="ACL8C7_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS1394965.1"
                     /translation="MSETILEIKELKKSFGDNPILQGLSLEIKKGEVVVILGPSGCGK
                     STLLRCLNGLESIQGGDILLDGQSIVENKKDFHLVRQKIGMVFQSYELFPHLDVLQNL
                     ILGPIKAQGRDKKEVTEEALQLLERVGLLDKQHSFARQLSGGQKQRVAIVRALLMHPE
                     IILFDEVTASLDPEMVREVLELINDLAQEGRTMILVTHEMQFAQAIADQIIFLDQGKI
                     AEEGTAQAFFTNPQTKRAQEFLNVFDFSQFGSYL"
     gene            21511..21753
                     /locus_tag="ACL8C7_000716"
     CDS             21511..21753
                     /locus_tag="ACL8C7_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HGS1394966.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGSSSGKTTAKARTID
                     EIKKSGELRIAVFGDKKPFGYVDNDGSYQGYATILN"
     gene            21795..22376
                     /locus_tag="ACL8C7_000717"
     CDS             21795..22376
                     /locus_tag="ACL8C7_000717"
                     /inference="COORDINATES: protein motif:HMM:NF012707.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HGS1394967.1"
                     /translation="MSVDADNRAEYLISNKVDITLANFTVTDERKKQVDFALPYMKVS
                     LGVVSPKTGLITDVKQLEGKTLIVTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLD
                     GRGDAFSTDNTEVLAWALENKGFEVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKL
                     GKENFFHKAYEKTLHPTYGDAAKADDLVVEGGH"
     gene            complement(22456..23103)
                     /locus_tag="ACL8C7_000718"
     CDS             complement(22456..23103)
                     /locus_tag="ACL8C7_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1394968.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(23100..23798)
                     /locus_tag="ACL8C7_000719"
     CDS             complement(23100..23798)
                     /locus_tag="ACL8C7_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394969.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            complement(23808..24560)
                     /locus_tag="ACL8C7_000720"
     CDS             complement(23808..24560)
                     /locus_tag="ACL8C7_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394970.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(24560..25324)
                     /locus_tag="ACL8C7_000721"
     CDS             complement(24560..25324)
                     /locus_tag="ACL8C7_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394971.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKLGAIFIPVAYMMVGGILWAILGLSYLEPVTTLALGY
                     QKDISLSLVSAHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(25420..25824)
                     /locus_tag="ACL8C7_000722"
     CDS             complement(25420..25824)
                     /locus_tag="ACL8C7_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394972.1"
                     /translation="MKRRKIYSLFCVVTIASSLFLPTVLARQIGDYDLTLPRWGSDTT
                     SELEKENASAGINNNDSTGGGKTLNTSIRSAYSGSDITPVYSLGSGSRIVMYYNGGGD
                     NYIGSGTRLAMAPQFGNHVRIHTSGSWSPDSY"
     gene            complement(26004..26636)
                     /gene="pyrE"
                     /locus_tag="ACL8C7_000723"
     CDS             complement(26004..26636)
                     /gene="pyrE"
                     /locus_tag="ACL8C7_000723"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HGS1394973.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSDLIHLAQEEGYITPEGLYLLKRFKEDQENWQEG"
     gene            complement(26670..27371)
                     /gene="pyrF"
                     /locus_tag="ACL8C7_000724"
     CDS             complement(26670..27371)
                     /gene="pyrF"
                     /locus_tag="ACL8C7_000724"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HGS1394974.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKILSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEEPV
                     AAYHAIKDEWTQDWN"
     gene            27686..27784
                     /locus_tag="ACL8C7_000725"
                     /pseudo
     CDS             27686..27784
                     /locus_tag="ACL8C7_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612010.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(28106..28819)
                     /locus_tag="ACL8C7_000726"
     CDS             complement(28106..28819)
                     /locus_tag="ACL8C7_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1394975.1"
                     /translation="MLKRFLALVWLRCQIILSNKSILLQVLVPFAFTYFYKYLMETQG
                     KVNDQQALVLLMMCLPFSLALAVGSPITIILSEEKEKYNLQTLLLSGVKGSEYILSTM
                     FLPFLLTFVIMGTTPLILGVTIVHTFNYITIVLLTSLSIILFYLLIGLTAKSQVVAQV
                     ISLPAMILVAFLPMLSGLDKTVAKITDYSFMGLFTKFFTKWEGFSWNETLIPNLTLLI
                     WIVLLLTLITITIRKKKIS"
     gene            complement(28812..29651)
                     /locus_tag="ACL8C7_000727"
                     /pseudo
     CDS             complement(28812..29651)
                     /locus_tag="ACL8C7_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061739.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(29855..31039)
                     /locus_tag="ACL8C7_000728"
     CDS             complement(29855..31039)
                     /locus_tag="ACL8C7_000728"
                     /inference="COORDINATES: protein motif:HMM:NF013094.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HGS1394976.1"
                     /translation="MNEQILISDEIDIDSRYSRTKGYYSLFYNEEYNKIQNKTVLVLG
                     AGALGCYISLSLSMYGVRKLIVADYDIIEPSNLNRQILYTESNVGKEKINVLSEKIHK
                     YNSDVQVVPISIKVSSVEELEKIVAEYGSIDFIVKAIDTPIDIIKIVNQFAVSHKISY
                     ISGGFNGCYLIIDNIYIPTIGSCFGCRNINKDINKYTLSDKTKWPTTPEMPAILGGIM
                     TNLIIKIFLGCYNEILIDNAYVYNMRNHALSQEKYVLENGECPICKKNNKVKDNNIRA
                     KTFIRSVCFCLLSGGVAFLSAIGQFTVIGTQLIVLFLGIIFAIYYAYYNKNIQTSLEN
                     IVWLFSSFEILFLLVNFRTFIQLPVDIFICMIIFLMLWIFIMLGIVCLSYYITLLFGK
                     EA"
     gene            complement(31211..32008)
                     /locus_tag="ACL8C7_000729"
     CDS             complement(31211..32008)
                     /locus_tag="ACL8C7_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M50 family protein"
                     /protein_id="HGS1394977.1"
                     /translation="MGLIDSMKSRKKINIFKISWDFNITLSEKLNYKRFNKNFEKILF
                     GIFPLALILQCFIMYIYRADILTNFQNFPITLNILLFWLLVVIISATIHEFSHAIIAN
                     NYQIEIPNCGIMLLLFNLAFFVDLSGVQFLKNKKQFLKIMLAGIASNSILSLTGLLVL
                     LFTSYKLLGLLFFIINLGMIFINSIPFFQYDSGIILRYLNSNNNNLNFQYIVQLLIAF
                     VIIYFPLSQLLQFLTPNIIVRSIGGVVVSILLSILYMIGRTKYVLRK"
     gene            complement(32400..32522)
                     /locus_tag="ACL8C7_000730"
     CDS             complement(32400..32522)
                     /locus_tag="ACL8C7_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394978.1"
                     /translation="MQDNFLFEEIEEISVPVSDFSAGLATGIGFGLAILALAGC"
     gene            complement(32543..32668)
                     /locus_tag="ACL8C7_000731"
     CDS             complement(32543..32668)
                     /locus_tag="ACL8C7_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394979.1"
                     /translation="MSDEVFLFEEIEEIVAPTDGEFLGEVLLGTGVVLLIGVACC"
     gene            complement(32799..33998)
                     /gene="divIB"
                     /locus_tag="ACL8C7_000732"
     CDS             complement(32799..33998)
                     /gene="divIB"
                     /locus_tag="ACL8C7_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HGS1394980.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEESES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     NQRSSRR"
     gene            complement(34008..35066)
                     /locus_tag="ACL8C7_000733"
     CDS             complement(34008..35066)
                     /locus_tag="ACL8C7_000733"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_function: GO:0051991 -
                     UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-
                     glutamyl-meso-2,
                     6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol
                     4-beta-N-acetylglucosaminlytransferase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0007049 - cell cycle [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0030259 - lipid glycosylation [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HGS1394981.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(35068..36420)
                     /gene="murD"
                     /locus_tag="ACL8C7_000734"
     CDS             complement(35068..36420)
                     /gene="murD"
                     /locus_tag="ACL8C7_000734"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HGS1394982.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQCLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYSNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIATD
                     KNTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLASKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(36524..37165)
                     /locus_tag="ACL8C7_000735"
     CDS             complement(36524..37165)
                     /locus_tag="ACL8C7_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1394983.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDSKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(37167..39188)
                     /locus_tag="ACL8C7_000736"
     CDS             complement(37167..39188)
                     /locus_tag="ACL8C7_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HGS1394984.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLSYKALVPVIKGR
                     LPLKRLMALTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEEGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGIKLLKNAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            complement(39259..39558)
                     /locus_tag="ACL8C7_000737"
     CDS             complement(39259..39558)
                     /locus_tag="ACL8C7_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HGS1394985.1"
                     /translation="MKTKKHRLLALALISNFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSLVSRWNSHSDKGEASAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            complement(39922..40176)
                     /locus_tag="ACL8C7_000738"
     CDS             complement(39922..40176)
                     /locus_tag="ACL8C7_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HGS1394986.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(40196..42037)
                     /gene="typA"
                     /locus_tag="ACL8C7_000739"
     CDS             complement(40196..42037)
                     /gene="typA"
                     /locus_tag="ACL8C7_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HGS1394987.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            42199..42924
                     /locus_tag="ACL8C7_000740"
     CDS             42199..42924
                     /locus_tag="ACL8C7_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016866 - intramolecular transferase
                     activity [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGS1394988.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVQVNGLLTPDHIQTFQKGIVFLDGTIC
                     KPARLEILSASPSFSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     ESNYRPLNQKELQIIKNYLEMSR"
     gene            complement(42964..43191)
                     /locus_tag="ACL8C7_000741"
     CDS             complement(42964..43191)
                     /locus_tag="ACL8C7_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1394989.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(43280..43660)
                     /locus_tag="ACL8C7_000742"
     CDS             complement(43280..43660)
                     /locus_tag="ACL8C7_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGS1394990.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(43660..43929)
                     /locus_tag="ACL8C7_000743"
     CDS             complement(43660..43929)
                     /locus_tag="ACL8C7_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HGS1394991.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            43993..44901
                     /locus_tag="ACL8C7_000744"
     CDS             43993..44901
                     /locus_tag="ACL8C7_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGS1394992.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(44955..45710)
                     /locus_tag="ACL8C7_000745"
     CDS             complement(44955..45710)
                     /locus_tag="ACL8C7_000745"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGS1394993.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEPDAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(45731..46660)
                     /gene="rnz"
                     /locus_tag="ACL8C7_000746"
     CDS             complement(45731..46660)
                     /gene="rnz"
                     /locus_tag="ACL8C7_000746"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HGS1394994.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTGASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(46675..47298)
                     /locus_tag="ACL8C7_000747"
     CDS             complement(46675..47298)
                     /locus_tag="ACL8C7_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HGS1394995.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTDQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGLGRIFFENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKLVEDEEVISLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(47291..48529)
                     /gene="hflX"
                     /locus_tag="ACL8C7_000748"
     CDS             complement(47291..48529)
                     /gene="hflX"
                     /locus_tag="ACL8C7_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HGS1394996.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPNLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(48522..49406)
                     /gene="miaA"
                     /locus_tag="ACL8C7_000749"
     CDS             complement(48522..49406)
                     /gene="miaA"
                     /locus_tag="ACL8C7_000749"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HGS1394997.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIQSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            49527..49697
                     /locus_tag="ACL8C7_000750"
     CDS             49527..49697
                     /locus_tag="ACL8C7_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HGS1394998.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(49745..50584)
                     /locus_tag="ACL8C7_000751"
     CDS             complement(49745..50584)
                     /locus_tag="ACL8C7_000751"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HGS1394999.1"
                     /translation="MTKADTIFKENIECILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(50681..51640)
                     /locus_tag="ACL8C7_000752"
     CDS             complement(50681..51640)
                     /locus_tag="ACL8C7_000752"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HGS1395000.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTFGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(51767..52765)
                     /locus_tag="ACL8C7_000753"
     CDS             complement(51767..52765)
                     /locus_tag="ACL8C7_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ltp family lipoprotein"
                     /protein_id="HGS1395001.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DIHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQSTAIQINTSSATTSGWVKQDGA
                     WYYFDGNGNLVKNAWQGSYYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYAKNAWQGA
                     YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDA
                     TYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTA
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDD"
     gene            complement(52815..53432)
                     /locus_tag="ACL8C7_000754"
     CDS             complement(52815..53432)
                     /locus_tag="ACL8C7_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HGS1395002.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRDLILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCPYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPYGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            complement(53433..55154)
                     /gene="pabB"
                     /locus_tag="ACL8C7_000755"
     CDS             complement(53433..55154)
                     /gene="pabB"
                     /locus_tag="ACL8C7_000755"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008153 - para-aminobenzoic acid
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HGS1395003.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLTVHKVPLLGEYLLYFTVHDRVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRSHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(55215..61064)
                     /locus_tag="ACL8C7_000756"
     CDS             complement(55215..61064)
                     /locus_tag="ACL8C7_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HGS1395004.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAEAVDPVVTLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAQPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEIKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPTEEP
                     KVEQVGEPVEPSEDEQAPTAPVEPEKQPEAPEEEKAVEETPKPEDKIKGIGTKEPVDK
                     SELNNQIDKASSVSPTDYSTASYNDLGPVLETAKGVYASEPVKQPEVNSETNKLKTAI
                     DALNVDKTELNNTIADAKTKVKEHYSDRSWQNLQTGVTEAEKVAANTDAKQSEVNSET
                     ASLKTAISRLNTDKVELENQLKIAQGKTETDFSMESWTVLSTAKNKAQEVKDNGTATQ
                     EQINEAEKSLKTALADLSVDKTALGSAIDTATKKNKENYTNQTWAELETALTAAKSVN
                     TNESKQSEVNEAVEKLTATMEKLVELSEKPRLTLSIEKRDIDRKATVTYTLENPANTQ
                     IKSITATLKKGEEVVKDFVLTEENLKTNHLTALFEKLDYYKEYTLSTDMVYNRGNDDE
                     TESISEELIQLNLKKLELKDIQTVSLMKFENGQESQVTHLSDKPTDLSKLYLKVTSST
                     SKDAVLAVSSIEEEIVENKKIFKIHADTPELVVRKKDGSLSKGFDYYMERVIPHDGDI
                     YYDFKDLISAMTSNPTGTFILGRDISSRNVKPDGNGKSYIKGEFKGKLLGTNDNVRHS
                     IFDLEYPLFDTIKSGVVKDIDFKHVNMVFPDSNQGDNVATIARVIKDKTKIENVNVEG
                     YLEGRDHVAGLVNNLEGNSEIENVSFTGKIKSKGGNSITAGIAGRNILSRVKRAYVNA
                     DIEVHRSSNSSMLVAVNGINADASGGWGTWGRLTESVAKGTLETKQGGQAGGASSTVW
                     PYGAIDNVVSYAKVTKGKELFGSDGDLNYDWFMKKISNIFGVQGISSGDSGSDSKFTR
                     ISEEEANQKVASYNITAPNLMSDSSLLVDRLNESWKNTDQFESIQDYQAQNQLIYQNL
                     TKFTPYYNKEFIVHEGNALTPEQEILKTKKIKSIVGLKGTEFVVDGSDIDTIMLHFED
                     GSQKRYKVTSTGKFSITNLPEYQVEDLNVVYTSEHIVHPLDSSLINNLVEELKKVELY
                     TESTYQVLGIDKDNANKLNRTKRLFLDESLDAVKTQLPTFVKTMFENEWLHINGESSG
                     AVAALRQKIMDNKTAILLALTYINRYYDVKFSDYNIKKLMLFKPTFHGEKIDLLDRLI
                     RLGSSGENRLKGSENAETFKQLFASETKQKDLVTYLDYNRSLLTNYQTTGEWFKETTK
                     DYIQFEERPSLVEEIKDAKYRVYDNLTAPYYQGYILPLLTLKNTHLAILSNYSTMTFV
                     SREKRPNWKNEDFDKWVKYVATAHRNHVDTWYKILPDNIKGKMVKENVTAVWEGLSIP
                     GSEWVDQNAVDRKGRDYAPAREFFNLVGGPMGGWYAYHGYGAHAGGRNRVNYEVFDVL
                     SEYGISVFTHELTHVNDTWIYLGGYGRRENMGPEAYAQGLFQSPVPGQPGWGALGLNM
                     AFERKNDGDLIYNASPTQFENRKELDSYMKNYNDTLMMVDYLEGDAVISKGKEAITKW
                     FKKVEPKVVSQTAQYDTVRQLTAEEKEKLSVSSVDDLVDQGLMSDRAVGNNTYNPADF
                     ETSYIAIDYMTGIYGGGKNSVGSPGALMFKHNTFRMWGYYGFEEGVLGYASNKFKQAS
                     RDEGHAGLSDNFIISKISKGEFLTMEAFKKGYFKKVVEELKTKGIRPVTINQKTYSTF
                     EELQEGFKQAVERDLKKNQLDERETRNFKFQVFRQLLQQTDSFKTSIFR"
     gene            complement(61086..61649)
                     /locus_tag="ACL8C7_000757"
     CDS             complement(61086..61649)
                     /locus_tag="ACL8C7_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HGS1395005.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALANRPKLIGGARAHYPQDAIRKS"
     gene            complement(61765..63456)
                     /locus_tag="ACL8C7_000758"
     CDS             complement(61765..63456)
                     /locus_tag="ACL8C7_000758"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGS1395006.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            complement(63453..64190)
                     /locus_tag="ACL8C7_000759"
     CDS             complement(63453..64190)
                     /locus_tag="ACL8C7_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGS1395007.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
BASE COUNT        19415 a        13986 c        11284 g        19650 t
ORIGIN      
        1 gatggactag aatgcttttt gaaagcagat gagtattata tgcaatttct ttatataaaa
       61 agaccggatt gctccgatct ttcaatagtt catattctca atttctattt taaaaatagc
      121 taaggttaac gtcaaatgac tacgcgacct atttcatacg ataaaaatca agcactagac
      181 cagcaggtcc ttgaactaat aaggactctg ttccccaatc ggttacagtt ggtccgtgta
      241 aaacctttat accaagctcg ttcaaccgtt tgtagttctg gtctacatcc tcaacctcga
      301 tatgaataat gattcctgac tgaaagtttt ccaaaggaac caaatgattt tgtgacaaca
      361 taaggcagtg actaccaatc gtaaactgag caaaaccatc atcagcataa tctgcctttt
      421 tatccaagat atgctccaag tcagcacaga cttggggaac atttgaaacg ataatatcta
      481 attgatttaa attcatttac tctcctccat aaaaagaccg gattgctccg atcttttaaa
      541 gttctgctct atgaaaatca aagaataaag tctacaagtt tcatatttga ttttcggcga
      601 gaggaattat ttaattgcgc gtgattgcaa tccttcttct tccaagaaga gacggaatgg
      661 tacgagttct tctgcttcgt atttttcctt gaaggctttg atagcttctt ctgagtgaag
      721 ttttggatcc aattcaagta cttctactgg aagtggacgg tgttgagtga tgcgagcatc
      781 gatgacaaca gttttacctt ctttgttcaa tttaacagct tctgcaacaa ctgcatcgat
      841 gtcttcgata cggtcaactg tgaatccaac agctccttga gcttccgcaa ttttagcgta
      901 gtcagcgttt gtgaagtcta caccaaacaa gtgtttgttt gtatcttcgt atttgttctt
      961 gatgaagccg tactcatcat ttgagaagac aaggttgata actggaaggt cgtattgaac
     1021 gtttgtgata acgtctgggt agcacatgtt gaatgctccg tcacccatga tgttccatac
     1081 ttggcgatct ggattgtctt tcttagcagc gataccacca ggaagggcaa tacccattgt
     1141 cgcaaagagc ggagatgtac gccacatgtt cttaggtgtc atgtgaaggt gacgagtaga
     1201 tgtttgagta gtgttaccta cgtcgattga gtagatagcg tcttgatcag catgtttgtt
     1261 gattgcattg taaacttgat acaattgcaa ttcaccctca gttttacctt cgagtttgtt
     1321 catgtaatca cgccagtttt ggttgttctt aacgtttgca cgccaccatg gagttgattc
     1381 aactgggttt actttgtcaa ggatagcttt agctgcttga ccagcatcac caaggattga
     1441 agcgtcaagg gcatgacgtt taccaagttt gtaagggtcg atatcaactt ggatgaattt
     1501 ttcagtgttc ttgaatgctt cgtaaacttc agcaaatggg aagtttgaac caaggaaaag
     1561 aactgtgtct gcttcaaaga ccacttcgtt ggctggtttc caaccaacac ggtaagcaga
     1621 acctgtcaaa ccttcatagt tccattcgaa agcttcaaag tttttaccag ttgtgataat
     1681 tggtgctttg attttacgtg acaattcagt aatcacttca ccagctttaa caccaccaaa
     1741 tccagcatag ataactgggc gttcagcatt gttcaagatt tcaacagctt tgtcgatttc
     1801 aacttcgttc aaagcaggag cgatgaatga gcgttcgtat gaacctgaac cgtagtatga
     1861 gttttcgtcg atttcttgga aaccgaagtt tactggaatt tcaacaacag ctggaccttt
     1921 tttagaaatt gcagcacggc aggcttcgtc aattactttt ggcaattgct cagcgtaagc
     1981 tacacgtttg ttgtaaacag cgataccgtt gtacattggg ttttggttaa gctcttggaa
     2041 agcatccatg ttcaattcgt taactggacg tgatccaagg atcgctagga atggagtgtt
     2101 atccatagct gcatcgtaaa caccgttaat caagtgagtc gcacctggac cacctgaacc
     2161 aactgcaacc ccgattgagc cgccgaattt agcttgcata accgctgcaa gagcacctgt
     2221 ctcttcgtgg cgaacttgta agaaacggat atctttgtct tcagccaaag cgtccatcaa
     2281 tgagctgagt gttcctgatg ggataccgta gattgtatct acgccccatg ttttcaatac
     2341 gttaagcatt gctgcagatg cagtaatttt cccttgagtc ataatgataa ctctccttca
     2401 atttttttaa acttggagaa tacgattaca tagaattgga aacgttctcc aaatttttac
     2461 tattccactg tatcatattt atgctgactt ttctaaaaat ctgctcaaaa ctctctattc
     2521 tctattctaa tacagttttg aaagtgttgt catttctgtt ttataacaaa gaaatctagt
     2581 cattactttt agtctatttt actaaaattt aacagaaggg aactggtcag aacagataca
     2641 gaactaaagg ccatggctag acctgccaat tctgggttga gagccagtcc aacacctgaa
     2701 aagactcctg ctgcaatcgg aattccgaca acattgtaga taaaagccca gaaaagattg
     2761 agtagaattc gatgaaaggt tttcttactc atatcaaagg cacgaaccac tcctaaaaga
     2821 ttattggttg tcaacaccaa atctgctgac tcgatggcga tatctgttcc agcacccata
     2881 gcaattccca catctgctac actaagggca ggagcgtcat tgataccgtc cccaacaaag
     2941 gctactttgc cagccgcttg cagtttatgg atttcatggg ctttttcttc tggcaagacg
     3001 cctgcaatga cctcttcaat tccgatttga tctgcaatag cacgcgccac accagcattg
     3061 tctcctgtca gcatgactgt tcggagacca cgttttttta gctgactgat ggctagctta
     3121 gcattttcct taggaatatc ttgcaaagca agcaagcctt tgatttcatt gtcaacagct
     3181 aagaacacaa ctgtcttagc ttctttttct agttcttcta gtttatcttg ataagtatta
     3241 gaaatatcca tgccatccag cattttagca tttccaagta aaacttgttt tccattgatt
     3301 cgccctgaaa cacctttccc gtgcaaggtc tgaaaatttt caacagtttg aaactcaagt
     3361 ccagcttcac tcgctcgctt aacgatagcc tcagccagtg ggtgttgaga agcatcttcc
     3421 aaggaggctg ccaacccaaa cacttctact tcgtcgccga tgacatctgt taccacaggt
     3481 ttcccttccg tcaaagtccc ggtcttatca aagacaagag tttgaacttt ctggatttcc
     3541 tgtaagacag ttccattttt gaggagaacc cccatcttgg cactacgtcc tgtccccacc
     3601 ataagggctg tcggtgttgc aagtcccaag gcacaaggac aggcgataat caaaaccgcc
     3661 actccgtaga gaagagagga cacaaagcta gctccaagca caaccacact atccctgagc
     3721 aagacgaacc aaacccaaaa ggtcatgatt cctaaaatga caactactgg gacaaaaatc
     3781 cctgaaatct tatccgtcaa gtcctgaatc ggcgcacgac ttgtctgagc tttcttcaca
     3841 aaatccacaa tctgagccaa aacagtctct gagccaactt tttctgctct aaagacaagc
     3901 gttacactat gattgatggt tgagccaatg acagtatctc caactgtctt gtccacaggc
     3961 agactctcac ctgtcaccat ggattcgtca atactagaga caccttctac tacgacacca
     4021 tcaacagcaa tcttttcacc gggacgcact cgaatcaggt cgcctacctt gacttgttcc
     4081 aaaggaactt ggacataact atcatcactc aagacttctg cggttttagc ttgcaagtcc
     4141 agtaatttct ccacagcttg ggacgtattt tttctcattt tttcctcaaa aactgctccc
     4201 aaaagaacga aaaagaggat aaatccagca ctttcgaagt aaacagggag accagcaaag
     4261 agagcaacta ggctatagaa ataagccact agagttccca gcgcaaccaa ggtatccatg
     4321 ttggcattgt gctttttaaa actggcccaa gcactctgga tatatggctt acctgcaact
     4381 aacataatag gcgttgttgc taaaaaggtt ccccaatgca tgacttgatg actaatgcta
     4441 cctgtcaaca tcccaatcat gagaatcaca agaggcacag taaagatact agtaatccaa
     4501 aaacgttgca ggagagatag agattttcga gtcttctcaa cgactgtata gcttcccttt
     4561 tgcatcttca tgccacaaga aaattcatgt cgccctaatt cttgaggcgt aaaacgaatg
     4621 actttctcct catctacgcc gattggttcc aagatacctt cttcttcaaa cagaatttcc
     4681 ttataacagt ttgaaggagt agcacgatga aaggtaatct cagctggaat tcccttttga
     4741 agctggatat gggctggatg atagcctttt tcagctcgga tacggatttt ttgaatgcca
     4801 ttttctaagc ttgctttcac aatttctgtc atagtctcca cctactctac aatcatcttg
     4861 ccgtgcatca tgttcatacc acaagcaaag ccaaactctc cagcctgttc aggcgtgatt
     4921 tccactacat actcttcccc cattggcagg ttcgcatgta caccaaaatc tggaaaaaca
     4981 atttgatcca gacatggtga aggatccttg cggtcaaaga caatgcgggc tggcactgat
     5041 ttcttgagga caatcaactc aggagtatag cctcccatga cttccactcg aatctcttgg
     5101 tatccgtttt tttgctgggc tttttgtcca gatttttcag gctttttgaa aaaccaaaac
     5161 aagataaacg cgataagggc aatacaaata atggttacaa tactatttaa catggcgtct
     5221 cctttacata caattacatc ttacttctgt tacagcactt gatttcttct ctgaaatcac
     5281 agcttccaag tcttccaagt cagtctgagt aaattcacat tctacaatca agtcagccaa
     5341 caaattccta atcctacggg aacaaacctt gtctttgata tcttggacaa gtaaatcccg
     5401 actttggtct agagttaaaa gcgctgaata aacaaagaac ttgccttctt ttttccgagt
     5461 caaacactct ttctcaacta gacgagccaa aagtgtctga accgtggact tggaccagtc
     5521 aaaccgctct gccaaaaccc taattaaatc tgtactggtc tgctccccct gcatccaaat
     5581 aatcttcatg acctgccatt ctgcatctga aatctgcatt accatacctc caaaatctac
     5641 atttgtcaat tacactcatc agtatactct taaaatctac atttgtcaat tatagaaata
     5701 atattttctt cgaaaaatag aattttaatc atttgaaaaa cgatttgcag tcaaatatta
     5761 ctatataaac aataaaaata tgctatacta aagaaaaaag aaaacaacca ctaggggtgc
     5821 gtaaagctga gattaacgac tgttagatcc ctctgactca atctaggtaa tgctagctga
     5881 tggaagtgga aatgataatg gggactagca gtcttctatt gcctttctaa aacagactag
     5941 cttgttctta agaatacaaa cttcagttgg ttgggaggtt ttagatgact tatttacccg
     6001 ttgctttgac cattgcaggg actgacccta gtggtggtgc tggcattatg gcagatttaa
     6061 agtcattcca agcgagagat gtctatggaa tggctgttgt aaccagtctt gtcgctcaaa
     6121 ataccagagg tgttcagcta atcgagcacg tttctcctca aatgttgaaa gcccaattgg
     6181 agagtgtctt ttctgatatt ccacctcagg ctgtaaaaac tggaatgttg gctactactg
     6241 aaatcatgga aatcatccaa ccctatctta aaaaactgga ttgtccctat gtccttgatc
     6301 ctgttatggt tgctacaagt ggagatgcct tgattgactc aagtgctaga gactatctca
     6361 aaacaaactt actacctcta gcaactatta ttacgccaaa tcttcctgaa gcagaagaga
     6421 ttgttggttt ttcaatccat gaccccgaag acatgcagcg tgctggtcgc ctgattttaa
     6481 aagaatttgg tcctcagtct gtggttatca aaggcggaca tctcaaaggt ggtgctaaag
     6541 atttcctctt tatcaagaat gaacaatttg tctgggaaag cccacgaatt caaacctgtc
     6601 acacccatgg tactggatgt acctttgctg cagtgattac tgctgaacta gccaagggca
     6661 agagtcttta ccaggcagtt gataaggcca aggcctttat cacaaaagct attcaagatg
     6721 cccctcaact cggtcatggt tctggtccag tcaaccatac aacttttaaa gattaagaaa
     6781 aaaactctct agttcccact ttaagggaat tagagagttt ttatactctt cgaaaatctc
     6841 ttcaaactac gtcagcttcc atctgcaacc tcaaaacact gttttgagct gacttcgtca
     6901 gtcttatcta aaacctcaag gcagtacttt gagcaacctg cgactagctt tctagtttac
     6961 tctttgattt tcattgagta ttaattagga aagaatgtca tgcaactttg ttaaaaaggc
     7021 ttgcgttttt gcctcaatat cttctgcttg catcaaatca cgtacaacag ctacaccagc
     7081 tatgccagtg cccataagct gatcaatatt ctccgaagtc aagcctccaa tagcaactac
     7141 tggaatggca accgtttggc aaattgtttt caaggtcgat atcagagtaa tgggcgcatt
     7201 ttccttggtg gtggttggga aaatggctcc tgtacccaag taatctgcac ctgatttctc
     7261 cgcttccaga gctcttttaa ccgttttagc ggtgacaccg aggatttttt caggacccaa
     7321 gacttgtcgg gcaaccgaaa ctggtaattc atcatctccg atatgcagac ctgctgcatc
     7381 aaccgcaaga caaacatcca accgatcatc gattatcaag ggtacctgat aagcatctgt
     7441 tatttccttg acttgttttg ccagttgata atattgattg gttgtgagat ttttttctcg
     7501 caattggact atggtaaccc ctgaacggca ggccgtctca acttttgcaa gaaagctttc
     7561 cacggaatct tgatagcgat tggttaccag atatagtcta agtgcttctc tattcataag
     7621 cctctccttt gatggtatct agccaatttt catctcttct taggagcgaa agctgattga
     7681 gtacttggta acgaaattct tccaatccca ttccttgaac aactattttc tcagcagcga
     7741 tattgagata agagactgct aagcaagaag cttcaaaacc agtctttcct tggctgagaa
     7801 aaacggctgt taaggctcca accaaatctc ctgtccctgt tatccagtct aattcagtac
     7861 agccattctc cagtacagcg acctgatttt tcgaaacgac gaggtccttg gggccagtaa
     7921 ctaagaatga cataccagga taggtctgac accagtcttt caagacttga agcaaatcct
     7981 ccgtttcttg atctttagca ctcgcatcga ccccaacgcc gtggtgcttt aatccaacaa
     8041 gacttcgaat ttctgacatg tttcctttaa tgaccgtagg tctatagtct aaaaggtctt
     8101 taactaagct cttacgaatg gatgaagtcg ttacgccaac cgcatctact accatcggga
     8161 gagaagattg gtttgcatac gaagctgcca tgcggattgc tttttccttc tcagctgaca
     8221 aatgccccaa attgatgaag agagcctgac tttgcttagt aaaatcaaga acctcacggg
     8281 gatcatctgc catgacaggt ttgcatccca gagccaaaat cccatttgcc agcatctcac
     8341 aagaaatctc attggtcata cagtgaatta gggaactaga gcctatagga aagggatttg
     8401 taaattcctg catcagtcta tcctttcact aaagaaatat ccctgcactt ttttaaagaa
     8461 ttcctgcttg attaaaaatc gaaaggcaat aaaggaaatc gctgtaccaa tcaaggttgc
     8521 tccgaaaaat cgaggcgtgt agataaacca gctaagctta gcagctgatc ctgtaaagag
     8581 taccataaca ggataggaaa caatagaacc aataatacct gttcccacaa tttctcccaa
     8641 ggcagaaaag taaaattttc gaccgtactt ataaaagaga cctgctagaa gggctccaaa
     8701 agtcgctcct gtgagagcta aaggcggaat cccttgagtc gtcatacgga taaaggctgt
     8761 cactgtagcc atagccaagg cataaacagg tcccatcatg attcccgcta gaatattgac
     8821 tacactggac atcggtgcca ttccctcaat tcgaaagata ggtgtaagga ctacatcaag
     8881 ggcaatcatc atagataaaa tggtcaattt gtgaacttgt agttggtgct ttctcatgtt
     8941 tctattcttc tcctttttct aaagactgta aatcgctctt ccatgtctgg tgttggtaag
     9001 ccatctccca aaacttggct tccatatgaa cactgatgtg gaaggcatct agcatttttt
     9061 gcttatctgt ctcatcactt tctcgataga gctgattgac cagtgctccc tcctctctga
     9121 tctgttgctc taactcatcc gtaatataag tttcaatcca ttgttgatag agaggatttg
     9181 gtgatggttt aagattaagt gatttgccta tatcatggta taaccaagga caaggaagca
     9241 agcttgcaaa agcgatggct aagttcggct ctgcaaattg cctataaata tgagaaatgt
     9301 aatgataaca ggttggagcg attggatgtt gctccatttc ctggtcgctg atttccaatt
     9361 ccttgaaaaa ttgttggcga ataaataact caccctccac taaaccctga gcattttgtt
     9421 tcaagagtct tttcatctct tggtttgaag tcttatcagc caaaagatga tagatttctg
     9481 agaaggcctt cagatagtag gcatcctgaa tcaggtaata gcggaaaatg gcaggttcta
     9541 aattcccctc ttgtaattgt aaaataaagg gatgatgaaa ggaagcctgc caagctttct
     9601 tggataattc catcgcaata tctgtaaatt ccataataac tcctttataa aaatagactg
     9661 gtttgaagca ataaaaagaa aagcaggtag attaattttg tttttttagg aatataaaaa
     9721 gtccgatagc tattcttcaa ctgtgcatgt tcgtcatatc cgtgagcaga tagagctctc
     9781 aggtaaagat ggcgccacct aaagactgtc atcagaacct tactgtaaat caagggcgac
     9841 caaaaatgta gtttttgacc acgtaatagg caagcttctt tgagggactt gatttcttgc
     9901 tgaatgagag gaaaagaatt gaataccaca atcaaggcat aggaccaaga gcgtgatagc
     9961 cccttttgag ccaagtacaa gagaagctct tttagtgaaa tagaggaaac aaagacaagg
    10021 ccgatacaaa ctgtcacaaa ggccctcgtt ccaagcatga ctgcctgtga agcatctccg
    10081 tgtaactgaa ctgcccagta gttggcaaaa gatggtaaaa tggcaagtat gatcatccaa
    10141 gctaacattt taaatcgacg gtaatagagc ataaagagaa tacaaaatgc gactaccgaa
    10201 agattcagag caatcgaagg aatgaaagat gtttccaagg ataaaatcag caagaagaga
    10261 ctgataatcg gtggctgggt tgctactttg accatactat ctcacctccc cttgggtatt
    10321 gctactctga gatgtaagtg gtttggtaat ggtcacttct ttcacatgcc gaagaccctg
    10381 actagtcatc tcaatccaat aatcaaccac agaaatcaaa gggtctaaac gatgactaat
    10441 gagcagaaaa cttcttcctt gattcctctc ctccacaatc cacttgcaaa aataatggca
    10501 ggctctatca tccaaacctg caaaaggttc atctagcaag atcacggaag ccttactggt
    10561 caagatggtc aggagctgaa gaattttttg ctgaccacca cttaattgat agggactctt
    10621 atcgactgcc tgctccaaat caaaatatcg taaagcttga aaaatccgct gatttctttc
    10681 agaatcaggt ccatctaatt gaagctcctc tcgcagactg actcggataa actgcttctc
    10741 agcttcctga acaacaccag tcagatcacg atacaaactc tttttctttt tcaggaccga
    10801 acccttccaa gtaatgctcc ccttatactt ttgaaattga agaatagacc gaaagagggt
    10861 tgatttcccg acaccattgt cacccaggat acaggaaatc ccttgataga atgtgaaatc
    10921 agcaattgaa aagagggggc gattaccaag ctcaccagtc acacggttca tatggaatag
    10981 ttccgggcta gaagcaactt cctttgaagc aacctgtgtc atctcatagg aagggatttg
    11041 aaacacttcc cttagttttc cgtctcttag ctccaccata tggtcgatat aggctttata
    11101 gtcagataaa tcatggtcgc acaaaataac tgtcttccca tcatagacca actcttttag
    11161 aatctccaat atctcgattc tgctcttgcg gtcaatggaa gcgaagggct catccaagag
    11221 atagacccta ggattcatgg caaagaggac agccagcgct gctttttgct tttccccacc
    11281 tgataagtga tggatgagac ggtgcaagat gtccttgcaa cgacattgct ggacaacctc
    11341 tgctatttta gaatcaattt cctgaaggtg atagccgata ttttccatgg taaaaaccaa
    11401 ctcctcaaac aagctctcca tggtaaattg atgattagga ttttgcaaga gaataccaac
    11461 cgtctggaca cgttcgacga tagaaagctg actgacctcg ctcccatcta tcaggacttg
    11521 accgctatag ggaagagaac taacttgggc aatcatttga aagaggctgg attttccaga
    11581 cccactactc ccaactaaca aggtaaaggc ttgcgcatga aaagtaaaat caaacggctc
    11641 agagaagatt ggggactgaa tcgctcgtag ttccagaccc atctatgctt ttcctccagt
    11701 tgcaaactga tgatagagtt tgacaatggc acgaaccaag atggtacaga agaaataaac
    11761 agaaataaaa cgtaccacaa gcaaggaaag gacaaacgga agggaaaagg cgtagtaacc
    11821 taacttaatg tattcataga caaagctaac aagcgtaatc ccaatactat tagcagttag
    11881 agagagccaa ctttcatagc gattcttagt tacgataaaa ccaaattcac ttcccaaacc
    11941 ttgaacaaag ccagacaaaa gagctcctag accaaattgg ctaccataaa ggacttcagc
    12001 aagcgcagct agcacttctc caatcgttgc acttccgact ctcggaacaa agatggcagc
    12061 aatgggcgca gccatacacc agagaccgaa gaggatttca ttggcaaagg cctgcaaacc
    12121 aagaggtgtt aagagtagac tgagaatatt atacacatat cctgaaccaa cgaaaacccc
    12181 accaaaaaag atagacaaga aagcaagcaa gataacatct tttaactgcc attttttcaa
    12241 cataaaaaac tccttttttt aaagaaaagt ggggcactca agaagaccga cctaaatact
    12301 ttgtatagca gactgaattt agaacagtac acaagaacac taaaatattt ctagaaatta
    12361 atttgaattt tctaattgat ttgttcgcat cttatttcaa tctactatat catcttcatc
    12421 cagtttcgta aaagaaaaaa ctctaattac agatacaaat tagagttcag cttacaagat
    12481 tagacagttc ttttcgacat acgaaaaaaa catttcacat ttcccttcgc cagtcttaac
    12541 tgtatcaggt tcaatgggta tcatctcagc ctaaagcacc ccaaatgtct ttattattta
    12601 attatgtgat tattataaca cacattttat actagttcaa gaaattgaac tggaaataca
    12661 gccttgcact cacaaagaca gcagatcttt cttttgcaaa aaacaaatga cctgtttgat
    12721 gaattagcca ttcaagctga atctggacat agctttttaa aaaaggaaaa tcctacttac
    12781 ttagaatcca aggatagata tctattgttc actcatttcc cgaacagttt tttctatatt
    12841 ttttgcatac gatattgccg aaatgattga aacgccatcc atattggtct ttataatgtc
    12901 tttaatatgt ttcgtctgta tcccaccaat tgcaactaaa ggcatttgtg gcaatagttt
    12961 tctcatcaat tcaagacctt cataacctat agtaccacca gcatcattct ttgactgggt
    13021 accaaataca ggcccaacac ctacataatc tacatattca acttttgatt gttgaaattc
    13081 ttcttcgttt cttatagaaa gaccaattat tttatctggc atcaattttc taatttcatc
    13141 aacaccaata tcatcttgac ctacatgtac gccatcggcg tcaatttcca ttgctaaatc
    13201 tatatcgtca ttaacgataa atggaacatt gtatttttta caaagttctt taatttggat
    13261 agctagctca agtttttcta agccttctaa agcaccctca cctttttctc gaaattgaaa
    13321 taaggttata ccacctttta aggcttcctc aacgactgta tatagatttt ttccttggca
    13381 agtagtcgtt ccacaaataa aatatagttt tagtaattct ttatgaaaca tcttacttca
    13441 ctcttttgaa ttcctttaca tcttcatctg taatctcgta taaggcattt ataaattcaa
    13501 ctttaaatgt cccaggaaga tgtccatttg gacgtttttc tgccatttct ccagcgatat
    13561 tgtaaaccaa cattgctgtt tctaatgatt tcaattcttg acctttttct agtccgataa
    13621 agcttgctac tacagctcct aataagcatc ctgtcccaat gactttcggc atcatagcac
    13681 taccattatg aatcattacc acttctccat taacagcaat ggcatccact tcacctgtta
    13741 ctactattgg aatattgaac ttctcatttg ctgctagagc aatttcgtca atattatcta
    13801 cgcccgcact atctactcct ttagatgcca catctattcc tactaaagag gcaatctcgc
    13861 cagcatttcc tctaatcgct gctagtttat aattgttgat tagatcatct gctacttttt
    13921 ttctatattc tcctgctcca caggctacag gatctaaaac tgctgggaca ttatatttct
    13981 ctgcaatttt cagagcagct tggtataatt tccaattttc atctgtcaat gttcctatgt
    14041 ttattaataa accaccagca tactttaaca aatcctctaa atctgctgga aactcactca
    14101 tggctggtga ggcgcccagt gctactaatc catttgctgt gaaatttttt actacatcat
    14161 tggttataca aatgaccaat ggtgcttttt cttttaataa ttttaaactt gtcatattga
    14221 aatccttcct tttcacttta tacgatctac tgatttcgat ttatttctat ctttcgttaa
    14281 gaattttttt catttacatt gaatgattta tactcaatga aaatcaaaga gcaaactagg
    14341 aggctaaccg caggttgctc aaaacactgt tttgaggttg tggatagaac tgacgtggtt
    14401 tgaagagatt ttcgaagagt cttacctcat caaatttgta aatatcatga gccttctcta
    14461 gacatcgtaa ccaatatcaa aaaaagctaa ttctaaagcg actgcttgat tccagcgttg
    14521 ctgaagttct gtcaaatctt ctcgattttt atcgacacga ttgagttcgt caaccagaaa
    14581 ttgaacccac tctgcaaaga aaggacctct gtggagattg atccattccg aatgaatata
    14641 gacttcaggt aaagccaaat ctttagaacc ccagtctaaa tagagacctt ctgcaatgac
    14701 cagcatgacc aaaagatggg catagtctga tgaagccacc gccgaataca ttagatcctg
    14761 aaaggctttt gttacagggt gcaaagtcac ttctagatag tcattctctg ctacttttaa
    14821 ctctttaaaa gccttttgga aataaccatc ttcatctgct tcaagaaagc ctagttgctt
    14881 ggcaaaacga agcttggatt caagtttatc tgcgtgagct acgcaggcac ccagcatgga
    14941 taagaaggca tcaaagaagt gataatcttg aatcagatag tcctttaaga ccttattctc
    15001 aattgtcccc gcaaaaagtt ccttaacaaa acgatgattg attgcagcct gccaatcctt
    15061 ctgactgctt tttaataatt ctccaacagt caaacctggc tgaaatgcat agtcttgtgt
    15121 ttccatattt acttctcctc tctttacttg ttagtaatta ataaaacacc aagaaatatc
    15181 aagcaaaatc gtaattccac ttgatccttt taaagcacat cgagagcatt tgcagagagc
    15241 taactaaaca agcctatcca gtttatataa acaaaaaact ccaattacaa tcaagaatta
    15301 gagttgactt acaagattag atcgttcatt tcgccatacg aaaaaacgtt tcacatttcc
    15361 cttcgccagt cttaactgta tcaggttcaa tgggtattat ctcagcctaa agcaccccaa
    15421 atgtctctat tatttaatta ctgaaccagt atagcaaaaa atgaaagccc tagcaagata
    15481 tttgaccgaa aaatatcttt atatataata tattgaaact agaatagtag acctctactt
    15541 ctaaaacatt gttagaaatc gatttaactg tcctgattaa tttgtcctat tcttatttca
    15601 ttttattata gttttcgata gcgatttatt cttccaatac acgaagaaaa acctccacat
    15661 tcagtggagg caatctgttt tatcaataca attttaagtc acgagggtca actgggaagg
    15721 ttgggttgta tggattgtga cggagcttaa agtgtttgac atcttcaatg gtctgagctc
    15781 cagacaattg cataactgtc ttcaattccg cattcaagtg ttcaaagact tgacgcacac
    15841 cgacactacc accgagagcc aagccataaa taacagggcg accaatagct accaagtctg
    15901 ctcctgaagc caaggcttta aagacgtgtt gaccacgacg aacaccagag tcaaagacaa
    15961 tcggcacacg tctatcaact gcttctgcca cttcttgaag cgagtcaaag gcagctggtc
    16021 caccgtcgat ttgacgacca ccgtggttgg ttacccagat accagaagct cctgcagcaa
    16081 gtgaacgttc aacgtcctca cggcattgtg gtcccttgac atacacagga agaccagagt
    16141 attcagcgat aaattctaca tcgcgtggag acaagcgttg tttagctgat ttgtaaacaa
    16201 agtccattga tttaccagca ccttctggca ggtattcttc aacaatcggc atgccaactg
    16261 ggaagacaaa accattacgc ttatccactt cacgattccc ccctacagta gcatctgccg
    16321 tcaagacaat cgctttataa ccttcagcct tcacacggtc catgatgtgg cggttgatac
    16381 cgtcatcctt actaaagtaa aattgaaacc aatgaggtgt cccttgaagg gcttcagaaa
    16441 tctctggaag gtcaacagta gagtaagaac tggttgtata aagagaacca aactcatgca
    16501 caccacgcgc agtcgccact tccccctgtt catttgccaa tttatgagcc gcaacaggtg
    16561 ccataatgat tggtgaagat agtttttcac ctgcaaattc aatctctgta cttggatttt
    16621 ctacattgca aagtgtatga ggaacgatga gcttgtggtt aaaggcacgg atattctctc
    16681 ttaaagtgaa agtatcttcc gccccactag cgatatagcc aaatgctgct ttaggaataa
    16741 cttgttgcgc cattggctcc aaatcatagg tattgatgaa gtctacatga ccttctgcat
    16801 tgcttgtttt gtatgacata aactgtcctc ctcgattaag taagcgtttg ctttttacta
    16861 tacaactata ataactcttt tttcaatcat tttcaagagt tttgcttaaa aaccatctta
    16921 ttttttcata caatatacta gccctacttt ccttaaactc taaaccttag tctatattaa
    16981 gtgaatcgtt gagatttttt gctgccaggc atttgaacta cttttttatt tgctgattct
    17041 atctactaat actataaaaa acaagtgaat aagacaccag aacatcctct aataggacct
    17101 atggacttat atcagtccca tatatactgt ttaagcaaga tactatccta gttgacgcta
    17161 acttcctatc ccacttatta attttttatt tatagtgaat ctgaacaaat caattgggga
    17221 atccaagtca atttctagta ctttttgaaa agtttcagcg tactatcgta aaatgaaata
    17281 aaacatgcac aaattgatta gggaatttaa accaatttct aacagtgtct tagaaatcaa
    17341 agtgtactat ttcaacttca atatactaca cttcattttc tccttaaatt cagtctcttt
    17401 ttgaatcaaa aaatcctctg gtaagaggca gaggataaga atttatttca ttgttgggaa
    17461 gagcaataca tcacggatag ttgttgtatc agtgaggagc atgcagagac ggtcgatacc
    17521 gattcccaaa ccacctgttg gtggcatacc gtattcaaga gcttcaatgt agtcatagtc
    17581 gattcctgtc gcttcatcat caccaagttc tttggcttta gcttgggctt caaaacggct
    17641 aagttggtcg attgggtcgt tcaactcagt aaaggcatta ccgtactcct tagtcatgat
    17701 aaagagctcg aaacggtcag taaagcgttg gtcttcagga tttttcttag cgagtggaga
    17761 tacagctact ggatgtccat agacaaaggt tggttggatt aaagtttctt caacaaactc
    17821 ttcaaagaag gcattgatga tgtgaccaac ctcagtgtag tgtttctcaa ctggaacttt
    17881 cttctcagca gcgatagctt tagcttcttc caaagtcatg tcttgccaga aatcgacacc
    17941 agtaatttct ttgatagcat ccaccatatg aacacgctta aatggtttgt taatcttgat
    18001 ttcagtacct tggtagttga ctgggccatc acctttgact gatttagcag cgtgttggat
    18061 aatgccttcc gtcaagtcca tgatgtcttg gaaatctgca taagcttggt aaacttcgat
    18121 agaagtaaac tcagggttat gagtagcgtc cattccttcg ttacggaaga tacggccaat
    18181 ttcatagaca cgttccatac cacccacaat aaggcgtttc aagtgaagct cagttgcgat
    18241 acgaagcacc atgtcaatgt tttgggcatt gtggtgggtg ataaatggac gggcagcagc
    18301 accaccggct tcattatgaa gaacaggtgt ttccacttca aggaatcctt tttggtcaag
    18361 gtaacgacgg atttcagaga tgatttttga acgagtgaca aagcgttcaa agctttcacg
    18421 attagaaatc aagtcaaggt aacgtttacg gtaaattgtt tcaacgtctg tcaaaccatg
    18481 gaatttctca ggaagaggac gaagagcctt agacaagtgt gtgatgtggg ttgccttgat
    18541 agagagttct cccatatccg tacgcatcac ttcaccttcg acaccaagga agtcaccaag
    18601 atctgctttt ttgaagattt cgtagttttc ttcaccgaca gcatccttac gaacgtagat
    18661 ctgaatctgg ccttcgcggt cttgaaggtg ggcaaaacca acttttcctt taccacgttt
    18721 ggttatcaag cgtcctgcga tagtagctgt ttcgttttta tcgtgtaatt gttctttatc
    18781 gaggttggca tatttatctt ttaattcttg tgaatttgca gtacgttcaa aacgttttcc
    18841 gaaaggatcg attccttgtt cgcggagcgc agccattttt tcacggcgaa cgatctgctg
    18901 gtcatttagt tcttccatat gttctgtaga catgggatcc tcctagtttt actcaaaatt
    18961 gaatacgatg agtcattttt tgcgataccc ccattttatc ataaataagc aagaaattca
    19021 cggataatct ttaaaaacta aaaagaacct gacgctaaaa tcactggaaa gaagtgaaag
    19081 tatctcccgc cccactagcg atatagccaa atgctgcttt aggaataact tgttgcgcca
    19141 ttggctccaa atcataggta ttgatgaaat ctacatgacc ttctgcattg cttgttttgt
    19201 atgacataaa atgtcctcct taataagtaa gcgtttactt tgtatattat aaaaatatct
    19261 taactctttt ttcaaaactt ttcaaatatt ttgtttggaa atttcagaaa ttttatgtct
    19321 atggtaaaaa atccttataa cggcaataaa aaatagatat tatccaaaga agattttaag
    19381 tgctacaata actgtattat ttctagatgg gaggttctat ttttggattg gtccattgtt
    19441 gaacaatatc taccactata tcaaaaggca ttctttctga ccttgcatat tgcagtttgg
    19501 agaattttgg gatcctttct gctcggttta atcgttagta tcatccgaca ttatcgaatc
    19561 cctgttttgg cgcaagtagc gacagcctac attgaattgt cacgtaatac gccccttttg
    19621 attcaactct tctttctcta cttcggtctt ccccgaatcg ggattgtcct atcttcagaa
    19681 gtctgtgcaa cgcttgggct tgtcttttta ggaggctcct atatggcaga atctttccga
    19741 agtgggctgg aagccatcag tcaaacccag caggagattg gcctcgctat tggtctgaca
    19801 cctctacagg tctttcgcta tgtggttctt ccgcaagcaa cagcggtgga actcccctcc
    19861 tttagtgcca atgtcatttt ccttatcaag gaaacctctg ttttctcagc agtggctttg
    19921 gccgacctca tgtacgtcgc caaggatttg attggtctct actatgagac agacattgcg
    19981 ctagctatgt tggtagttgc ttatctgatc atgctgctac ccatctcact ggtctttagc
    20041 tggatagaaa ggaggttccg ccatgcagga ttcggaaatc caagtactct ttcagggaaa
    20101 taatctcctg agaatcttac agggattggg cgttacgatt gggatatcca tcctgtctgt
    20161 cctcttatcc atgatgttcg gaacagtcat gggaatcatc atgacctccc attctagaat
    20221 catacgattt ttaacacgat tgtatctgga atttatccgt atcatgcccc agctggtgct
    20281 actcttcatc gtttactttg gcttggctcg aaactttaat atcaatatct caggtgagac
    20341 ttcagctatt atcgttttta ccctctgggg aacagctgaa atgggagact tggtacgtgg
    20401 agctatcact tctctcccta aacatcagtt tgaaagtgga caagcactcg gcttgactaa
    20461 tgttcaactt tactaccaca tcatcatccc acaagtcttg agaagactgc taccgcaggc
    20521 tatcaatctt gtcactcgga tgattaaaac cacttcatta gttgttttga ttggggttgt
    20581 ggaagtgacc aaagttggac aacaaatcat cgatagcaat cgcctgacca tcccaactgc
    20641 ttcattttgg atttatggaa ccattctagt cttatatttc gcagtttgct accctatttc
    20701 caaactatcc actcacttag aaaaacattg gagaaactaa atgtctgaaa ctatcttaga
    20761 aatcaaggaa ctaaaaaaat ccttcggaga caatcccatc ctccaaggac tttctctaga
    20821 aattaaaaaa ggggaagttg ttgtcatcct agggccatct ggttgtggga aaagtaccct
    20881 ccttcgttgc ctcaacggct tagaaagtat tcaaggtgga gatattcttc tggatggtca
    20941 gtctatcgtt gaaaataaaa aagattttca cctagttcgc caaaagattg gcatggtctt
    21001 tcaaagttat gaactctttc cccatctgga tgtcttacaa aacctcatcc taggccctat
    21061 caaagctcaa ggaagggaca agaaagaagt aacggaagaa gctttgcaat tactagagcg
    21121 tgtcggtttg ctggataaac aacatagctt tgcccgtcaa ttatctggtg gacagaagca
    21181 acgtgttgca attgtccgtg ccctcctaat gcatccagaa atcatccttt ttgacgaggt
    21241 gactgcttcg ctggatccag aaatggtgcg tgaggtgctg gaacttatca atgatttggc
    21301 ccaagaaggc cgtaccatga ttttagtaac ccacgaaatg cagtttgccc aagccattgc
    21361 tgaccagatt atcttcctcg accaagggaa aatcgctgaa gaaggaacag ctcaagcctt
    21421 ctttaccaat ccgcaaacca aacgagccca ggaattttta aacgtctttg actttagcca
    21481 attcggctca tatctataaa ggagattctt atgaaactat tcaaaccact cttaactgtt
    21541 ttagcacttg cctttgccct tatctttatc actgcttgta gctcaggtgg aaacgctggt
    21601 tcatcctctg gaaaaacaac tgccaaagct cgcactatcg atgaaatcaa aaaaagcggt
    21661 gaactgcgaa tcgccgtgtt tggagataaa aaaccgtttg gctacgttga caatgatggt
    21721 tcttaccaag gctacgctac gatattgaac tagggaacca actagctcaa gaccttggtg
    21781 tcaaggttaa atacatttca gtcgatgctg acaaccgtgc ggaatacttg atttcaaaca
    21841 aggtagatat tactcttgct aactttacag taactgacga acgtaagaaa caagttgatt
    21901 ttgcccttcc atatatgaaa gtttctctgg gtgtcgtatc acctaagact ggtctcatta
    21961 cagacgtcaa acaacttgaa ggtaaaacct taattgtcac aaaaggaacg actgctgaga
    22021 cttattttga aaagaatcat ccagaaatca aactccaaaa atacgaccaa tacagtgact
    22081 cttaccaagc tcttcttgac ggacgtggag atgccttttc aactgacaat acggaagttc
    22141 tagcttgggc gcttgaaaat aaaggatttg aagtaggaat tacttccctc ggtgatcccg
    22201 ataccattgc ggcagcagtt caaaaaggca accaagaatt gctagacttc atcaataaag
    22261 atattgaaaa attaggcaag gaaaacttct tccacaaggc ctatgaaaaa acacttcacc
    22321 caacctacgg tgacgctgct aaagcagatg acctggttgt tgaaggtggc cattaactct
    22381 taaaagggac tggattttaa gctccaatcc ctttttaaga ttttacctat aacatcctga
    22441 gtctatctaa gatgttcaat ctgaacacag tgtacatact ttatcttcta ttgcatatac
    22501 tttatcacat aagatacgaa tatcctcttc actgtgacta gcaatcaaaa ttgttgtccc
    22561 tttttcacta gagagctttc taaacaatgt tctcatattt tctacacttg atttatccaa
    22621 ggcattcata ggttcatcta gtaaaagaat agagggattc tccataattg cttgagcaat
    22681 ccctagcttt ttcctcatac ctagcgaata agttttaact ttctggtctt tttgctcata
    22741 tagaccaact attttcagtg tatcattgat ttcctgatta ccaactactc ctcgtatgct
    22801 tgccaaatat tgtaaattct taaagccact ataataattt ataaaaccag gttcttcaat
    22861 caaagctccc aaattagctg gaatttttct ctcaggaaca atattttccc cattgattaa
    22921 cacttctcca taagacggac tatataaacc agctattaat ttaaacaata cacttttccc
    22981 tgagccattc gcaccagtaa ttcctataat ttccccctgt ttacaactaa aattaaggtt
    23041 ttgaaaaaca catgtttttt ttaatttcaa ctcaatattt tttaatatga ttatttcatt
    23101 cattctataa acctcctctt ttgacgagtg aaatagaaaa tacttttaaa aagaaagact
    23161 aaaaatagca actgaagaaa taaatctcgt cctatatctc cattccctcg attcaaaata
    23221 taaaatagat aattagttcg atttcctaca aatagaccac caaacacaat catgagtaaa
    23281 aagaaactaa cgcaagcaaa gttcatttgt acattcgctc ctagtgcgta taacataaag
    23341 caaaacaaga ctaacacaca agcattcaaa gaatcaacta taaacaaaac tcctatatcc
    23401 cagtttggta actgtaacat aaattgaatc actagaactt ttaccatgat taaaatgagt
    23461 ccataaagaa aacaggtcca aatctgatac ctaatccaga gcttaataga agaaaatcga
    23521 atcacttcca taaagaaatc ggatgctctt ctacgatata caactgctag aaaaaatgta
    23581 tgaataataa accaatgaag caaccatata gataagacta aaaaagagtt ttgactcaga
    23641 ttaggccctt ttaaaatttc tataacaagt ctatcatttc cttctaacca ataccataat
    23701 cctaaacaaa tcaatatcca aaaaagaaca taaccccaaa agtacttggt atagattatc
    23761 tgattcaacc tccacatgtg actacttaac tttcccattt ccaactttta cactctcctc
    23821 cagtttctat gaacagaaaa tacagtcaat ggaattatga tagatagtaa tgtaagccaa
    23881 taaatcaatg catacggatt ggaatttacc atatactgaa aaattggcaa taatccaatt
    23941 atcccattgt ccaactgata aatccagaat aaggattcta caaataaaaa agtaaacaga
    24001 aatactaagc tcatgtttga ttttttaaac caagaaaaac tgctaatagt aagtaaggat
    24061 aaaaagaaat agtatgctat ataagagaaa aaaaatccta taaagaaact agcattgttt
    24121 gcaatactta taccataaaa ttctcttaaa aaatcaacct cctttatctc caaagagaag
    24181 ctaaaaccat tactaaatgc aattagaaaa atcaataaaa ataaagtcgc cgtccaaatc
    24241 cccgtactaa gagctgctaa tttgaaacta aaactggtaa agtgcttaat tgatttcaga
    24301 cgaatgcgac actccaacct attaaaatag ttattcatca aataaaaaaa gaacaatata
    24361 tatgtgaacg gaaagcaata tactccagtc gtcatatctt gaagtaaaac taagatccat
    24421 tctaatacat ttggatggat tgaatattgg cgacagcgca ataaatatac tgtactagat
    24481 aaaacacagg atagcagtaa tataaaataa accaatactg ctaagaaatc ttttttataa
    24541 aattgaacaa attgtttcat tatacatagt cctctgaatg tagaaaaaat gtaccataaa
    24601 caaccaaaca actaacaaat aaaataaaag caagatgagc actaactaag gaaagactga
    24661 tatctttctg atatcccaaa gctagcgttg tcacaggttc taagtaagat agccctaaaa
    24721 tagcccataa aataccacca accatcatat aggcaactgg gatgaaaata gctcctaatt
    24781 ttttcttcac tagcaaagca ctagctagtc caaaaataga gaacacagcg ccccaaactc
    24841 cataccagag agtcgtcaca agactataga gcaactgatt ggaatcaaat aattctttta
    24901 aggcaccact ataatctcca atataaattt cctgataagg agtcactaaa agattaattc
    24961 ctaataataa taaatagggg agaaaaaaga ctagaaaaga agaaataatt gcagtactac
    25021 ctacaatagc tagatacctc tttttagaaa ttcggcacaa ttgtgctgtt agaaaatgac
    25081 tctcagcatc ctctattatc tgactagaat agggcagtgt acagataagt gcagctacta
    25141 ggctaatcgg tgaaaatcct cgaatagaag aagcggcaaa aaaaatcgat aaaccttcaa
    25201 ttttataaat accattgaaa gcaaggaaat ttcctaaact catgcaaaga agggtcaaaa
    25261 ataaagacat ataaaatcga ggtgattgaa cgactcgtac aagattacaa atgaaaaatt
    25321 ccatccttac tcctccttat aataaaaata gggtgtagca ttcttttttc atgctacacc
    25381 cacaatcaac catctttaag gcttactctg acaagtaagt taataagaat ctggactcca
    25441 agaacctgaa gtatgaattc ttacatgatt tccaaattgt ggcgccatag ctaatctagt
    25501 accagaacca atataattgt caccacctcc attatagtac atgacaatcc tagagccaga
    25561 ccccaatgaa tataccggag taatatctga cccactatag gcgctacgaa tagaggtatt
    25621 taatgtttta ccgccaccag tactgtcatt attattaatt ccagcagagg cgttttcttt
    25681 ctcaagctca ctagttgtat ccgaacccca acgtggcaac gttaaatcat aatctccaat
    25741 ctgtctagct aaaactgtag ggagaaacaa actagatgca attgtaacta cgcaaaaaag
    25801 ggaatatatt tttcttcttt tcatgacatc gtcctcctaa gaagtgataa ataagatagt
    25861 tgattgatca atttgataca tattatattt tcattatatc aacaaaagaa agcgttgtca
    25921 attattttgt ttaaaatatt gtcatatttt aaacaaaatg gtaaaagagg ctcggtagcc
    25981 tcgtctctct ttatcttact gacctaacct tcttgccaat tttcttggtc ttctttaaag
    26041 cgttttagaa gataaaggcc ctctggcgtg atgtaacctt cttcttgggc tagatggata
    26101 agatcgctat agtttgaaag cgtcacaagt ttaacaccag catctgcaaa gttcttatct
    26161 gcttttggca attggtagct gaaaatcgct acaactccaa gcacatctgc tccttctcgc
    26221 ttggctgctg ctacagcttc aagaactgaa ccacccgttg aaataaggtc ttcaaccact
    26281 accatttttt gaccttgagc tacgcgacct tcgatttgat taccagctcc gtggtctttt
    26341 ggtttgctac ggatgtaggc aaaaggcaag tccatcttat cagcaataat ggctccgtgt
    26401 ggaatccctg ctgttgcagt tcctgcaatc acttctactt caggaaaggc ttctttgata
    26461 gcttccacaa aaccattttc aattagggta cgagtttctg gataggctag tgtcacacga
    26521 ttatcagtgt aaatcggtga cttgatacca gatgcccaag tgaagggttc ctctggtttg
    26581 aggtaaacgg cttggatttt caagaggtgg ctagcgatat ctttagcaag tgtcatggta
    26641 ttctcctttt atttttctaa tctagttctt taattccagt cctgtgtcca ttcatccttg
    26701 atggcatgat aagctgcaac aggctcctca gcttgggtaa tgggacgtcc cactacgata
    26761 tagtcactgc cgatttgata ggcatcagca ggtgtcatga ctcgtttttg atctccaact
    26821 gcaacaccag ctggacgaat ccctggtgtc agacagataa aatctggatt ggtagcctgc
    26881 ttgatgactt gtacttcctg agccgagcaa acaacaccat ccaagccagc ttcagctgtc
    26941 ttcttggcat agtgaatcac agactcttgc agactggttt ggatattttg aaactcctgc
    27001 atctgagctt ctgacgttga tgtgagctga gttacagcga tcaatttagc ttgacttcca
    27061 agaccttcac gcgcagcctt catcatctct acaccaccag ccgcatgaac attggtcata
    27121 tccacaccaa gctgagatag gatcttcatg gctgacttga ctgtattagg aatgtcatga
    27181 agtttgagat ccaaaaagac actatgaccc aaacctttta agtaggacac aatctcaggc
    27241 cccgctgcgt aataaagctc catccctacc ttgagataaa ggctttcttc tgctgggaaa
    27301 agagctaaaa attccttgac cgcctcaaaa ctaggaaaat caagagcaat gattggacga
    27361 tgttctcgca taggtttctc cttttacctt tactagtgag agagtctggc caacagaagc
    27421 cacgaaaaaa ggaacctgcc aacagcaagg ttccacgaaa aatgggtagt ctccaccctt
    27481 tcaccgtcta accttagctg cctctctgga ctgctttaaa ggttttttac tattctatta
    27541 tttctactag cacttgtcaa gtaaaaacat ggtcacgtat gtgttgactg ctattgaaca
    27601 cctcacaaga ctctttccaa aagaatagtt aaagactttc acttaggaca gagaaaaaga
    27661 gtttgcttgt taccctttaa ttgaacaaat gggaattctg ttttattttg cggatgccta
    27721 ttcatcttgg caaaggggaa gtaatgagaa tgcgaatgga cttcttcgtg agtattttct
    27781 taaaccgatt tggcaacaat taccgaaaaa atccttaatg gtgctttgct agcttattaa
    27841 tcaccgtccc caaaaatact tggattacaa gacaggtttt gaagcactta tagaggagat
    27901 ttaaaaatgt tgcatttttt attgcaattt atcagttatc ttatcaccca aaacttctgc
    27961 aattagtatg agcactattg ttatttttct tttttcgtac actcaaatca aaatatagca
    28021 ataagactat tctgtagaat tgctgtcaaa aagatcagtt catttttcct tcccacttgt
    28081 gtttataatc attaaaataa ctcaattaag aaattttctt tttcctaata gttatcgtaa
    28141 ttaaagttaa tagaagaaca atccaaataa gtagtgttag attaggaatt agagtttcat
    28201 tccatgaaaa tccctcccat tttgtgaaaa acttagtaaa cagtcccata aaactataat
    28261 ctgttatctt cgcaactgtc ttatccaaac cagatagcat cggtaagaaa gcaactaaaa
    28321 tcatagcagg aagactgata acctgagcta ctacttggct cttcgcggtt aaacctatca
    28381 ataaatagaa taaaatgatg gataaagagg ttagaagaac gattgtaata taattaaaag
    28441 tatgtacaat tgtaactcct aaaataagag gagtagttcc cataatcaca aaagttagca
    28501 aaaaaggaag aaacatcgtt gataaaatgt attcggatcc tttaacacca ctcaacagaa
    28561 gagtttgtaa attgtacttt tctttttctt cagacaagat aatagttata ggacttccaa
    28621 cagccaaagc caaagaaaaa ggtaaacaca tcatcaaaag aactaatgcc tgttgatcgt
    28681 tgaccttccc ctgtgtttcc ataagatatt tataaaaata tgtgaaagca aaaggcacta
    28741 aaacttgcaa taaaatactc ttattggaaa ggataatttg acaacgcaac cataccaaag
    28801 ccagaaaccg tttaagcatt tagctttcct cctgttaatg tgataaaaat atcttctaaa
    28861 gtaggctcac atgaatgaat tgaaaaaata ttttccagat cagcctgaga tacctgttct
    28921 agtgatgtaa aatcaaaagt tatctaattc ccattataat ctgtcaactt aatcttttta
    28981 tctttattat atctttgaat gagttcagaa ggagctcctt gctcaactaa tttcccttta
    29041 tttaataagg caacataatc acataaaaga gttgcttcat tcatatcatg agtcgttaga
    29101 aaaatcgttg tccctgctgt tttcaattct aaaattaact catgaattgt tcgagaagtt
    29161 gtgggatcta gacctgaggt cggttcatcc agaaagagta cagcgggttt gttgataaga
    29221 gctcgtgcta aaagcattcg ttgcctcatt ccagtggata attttcctgc taccatcttg
    29281 cgactatcat ataatcctac tcgctttaac aaattatcaa cacgtgattt actaatatta
    29341 taaaatttac tataaaaaag aagattgtta tacagagaca ttttctcata aaatccactt
    29401 gtatcgctaa ccaatccaat tctctttaat tcaccgcttg ttaaattttg agatttttgt
    29461 cccaaaataa tagattgtcc tttatcggca aggaactgcc cagtcagaat attaatcgtt
    29521 gtggtctttc cagaaccaga tggtcctaaa aatccaaaaa tctaaccttc tttaacagtg
    29581 aagcttatat tatttaaagc tattttatca ccaaaacttt ttgataaatg gctaacttca
    29641 atcatactca ttgcacctcc tttatattct acatttttac ttaacatcta tttacttatc
    29701 tttatcaaat aaacgtctta aaaaaaacaa taacattaag catataaccg ttagcaagat
    29761 tgtttcaata ttattgataa tatgatacat tctcaagcag tataaaataa ttatatatat
    29821 gcaaatgctc attataccta tttttttaaa catactaagc ctccttgcca aataataaag
    29881 ttatataata actaagacac actataccta acataataaa tatccacagc attaaaaata
    29941 ttatcataca aataaaaata tccactggta actgaataaa tgttctaaaa ttaacaagca
    30001 aaaataaaat ctcaaacgat gaaaaaagcc atactatatt ttccaatgat gtttgaatat
    30061 ttttattgta gtaagcataa tatatagcaa aaataatacc caagaacaat actattaatt
    30121 gtgttcctat aacagtgaac tgcccaatag cagataaaaa agctactcct cctgataata
    30181 agcaaaaaca aactgaacga ataaatgttt tcgctctaat attgttatct ttcactttat
    30241 tatttttttt acaaattgga cattctccgt tttccagaac atatttttct tgacttagag
    30301 catgatttct catattataa acgtaagcgt tatctattag gatttcatta taacatccca
    30361 gaaatatttt aattattaaa ttagtcatta tccctcccaa aatagcaggc atctctggtg
    30421 tagtcggcca ctttgtctta tcagataaag tgtacttatt tatatctttg tttatattcc
    30481 gacaaccaaa gcaagaaccg atggtaggga tatatatatt atcaataata agatagcatc
    30541 cattaaaccc tcctgatatg taggatatct tatgcgatac agcaaattga ttgacaattt
    30601 ttataatatc aatgggcgta tcaattgctt taacgataaa atctatactc ccatattccg
    30661 caacaatttt ttctaattct tctactgaag aaactttaat agaaataggt actacctgaa
    30721 catctgaatt atacttgtgt attttttcag aaagaacatt aatcttctcc ttaccaacat
    30781 tcgactctgt ataaagaatt tgcctattta aatttgatgg ttctattata tcgtaatcag
    30841 cgacaataag tttcctcact ccatacatac ttagacttag agatatataa catcctaagg
    30901 ctcctgctcc taatactaat actgttttat tctgtatttt attatactct tcattataaa
    30961 ataacgaata gtaaccttta gttctagaat atctactatc aatatctatc tcatccgaaa
    31021 ttaaaatttg ttcatttata gttcaaatgt tagtttactg cctaatactt cttctatctc
    31081 taatagttcc ttacaactat taaatagatc gttgataaat tcttgcgaaa tttgaggttc
    31141 tatagctatt tcccgcatac tccgaccacg taaatacatt ataccttctt ttttataagc
    31201 aaaaacataa ctatttacgt agaacatatt tcgtccttcc tatcatatat aatatagaaa
    31261 gcagtataga aacaaccacc cctcctatac tacgaacaat aatattgggt gtcaaaaact
    31321 gtaatagttg actcaaaggg aaataaataa taacaaatgc tattaaaagt tgaactatat
    31381 attgaaaatt caagttatta ttgttagaat tcaagtatct taaaataata ccactatcat
    31441 actgaaaaaa aggaattgaa ttaataaaaa tcatacctaa gttaatgata aaaaataaga
    31501 gtccaagcaa tttatacgat gtgaacaata aaacaagtaa acctgtaagt gataaaatcg
    31561 aatttgaagc aattcctgct aacataattt tcaaaaattg ttttttattt tttaggaatt
    31621 gcaccccact taaatctaca aaaaaagcca aattaaacaa aagtagcatt attccacaat
    31681 ttgggatctc aatttgataa ttattagcaa ttattgcatg actaaattca tgtatcgttg
    31741 cagatataat aacaacaagc aaccaaaata aaagaatgtt tagcgttatt ggaaagtttt
    31801 ggaaattagt caaaatatcc gccctataaa tatacataat aaaacattgc aaaataagag
    31861 ccaatgggaa aataccaaat aggatttttt caaaattctt attaaatctt ttatagttta
    31921 atttttcaga taatgttata ttaaagtccc aagatatttt aaaaatattt atcttttttc
    31981 gtgatttcat agaatctata agtcccattt tactaagaac aatataaaat cttaaataat
    32041 atttcttccc tactaacact aataagtccg atatggtaaa ttcttgacct attagttgct
    32101 ctaaccattt ttttcctgtt tcccaactaa tacatgtttc ttactggatg gtatatatag
    32161 atgatactgt ccctcataag gagtaggtaa tatcttaatc ttatcaacaa ttctcataac
    32221 aaacctaacc tttaataaat aaaagagggg ctaagtaaaa catactctag tccctcagtc
    32281 cgcaatcaat aaaataatga ctaattctat taatctcttg ctgcaagact aatacggaaa
    32341 attcaaatga ctgtctaaaa tgaaattgaa aaagcttgat gttagtaaat gaacaaactt
    32401 caacaaccag caagagcaag gattgctaaa ccaaatccga tacctgttgc aagtccagct
    32461 gaaaaatcac taactggtac tgaaatttct tcaatttcct caaataaaaa gttatcttgc
    32521 atgattatca ctccctatct ttttaacaac aggctactcc aattaagaga actaccccag
    32581 ttccaagtaa aacttccccc aaaaattcac catctgtagg ggctacgatt tcttcaattt
    32641 cttcaaataa gaatacttca tctgacatat gtgttacctt cttcatcaaa aattattttg
    32701 taatcgatta catttcagat gtaacataaa gaaaaacaaa tgtcaaatat taaacgtaaa
    32761 aacatggtca ctaaagaact ataagagaaa aggtaaacct agcgacgcga tgaacgctga
    32821 tttgtttgat ttcgattgct ctcttcctct tgttttttct gttcttcttc ttgttttttc
    32881 tcagcttcct tggcctcttg tttggctttt tcctcagcct ccataattaa tttatccgcc
    32941 acagtgtaac tgtaaattcc agcttccatg tcgaccacac tcggttctga caattgtggc
    33001 ttaatcttac tgtaatatgg cagtttctta ctcatttcag atagaggaac caagacttcg
    33061 tccgaatcat tcatggtcaa tcgaattaaa tcggatgtca ccttgcttgg ggctaattcc
    33121 accttttgga tagccgcctt gagttctggg ctaatttgag caagttctga gacaaaaacc
    33181 ttgatttgtt cactatcatt aaagagaact gataaataag tttctggtaa actgttcaga
    33241 ctcacagaac tagtctcaag ctgaccactg gaaagaatag gataatgatt ttcaccagaa
    33301 atatagtagg ccacaatatc atattccttg accttaatag tgaacttagt tggaaattga
    33361 tagacaagtt gagctgattc aacccaatag ttagacttaa tctgcttttc atattttgcc
    33421 ttgtctagca gaaggttaat cgtataatcc gaatcctgaa tgcctgaagc ctgtcgaata
    33481 tcatcagctg tagtttgcac cgttccctca acacgaatat ctttcatggt cgcataagga
    33541 ctgagcaagt aggcagagac aatcaataaa agcagacttg gaaataaaat cgtgaaggct
    33601 cgcaagatat ggataccagg aatctttgct ttggctggtt tttcctttgt agccttttta
    33661 gcaagctttt tatcctgttc ctccttctct ttagactctg attcttcttt ctcttctttc
    33721 tctttgtcag cctctgagga tgctactttt tcttcagact cttccttagc tgattctgaa
    33781 tcttcctggt ctgtttcact ctcctggtcc tgtttgtcct ctgacttctc agattcttct
    33841 cccatccgag cttgtctttc cttttccttc tcctcagcta gagccgcttc ttcttcagcc
    33901 ttctttttta gatattcttg gtttcgtttc tgccattctg ataactcttt caattcttcg
    33961 aggatttctt tgtcctcatt tttcttatct tttgacattt actttcctta tgataaatct
    34021 tttttcaaca attgataaaa atctgctaga gatttcaatt ccttagaagc tttcatctta
    34081 gcttggtaat cttccttgtg acttagtaag tgagaaagct tctcttccaa actatccaag
    34141 gtcaaatcgc tttcttgaag gtcttctgca tagcctttct taacaaagta agctgcattt
    34201 tcaatctggt caccacgact agcttcacga ccaagtggca caatgacatg caattttgct
    34261 atcgccaaga gctcaaaaat cgtattggca ccaccacgtg tcacaacaat atcagccaat
    34321 tccatcaagg gttgatagag atcggtcaca tagtcaacac gaaaaagatt ttggctcaac
    34381 tcattcaggc tagaatctcc agttagattg ataatattgt agcgctctgt tagttctttc
    34441 ttatggtctg tcaccaattg gttaaagaca cgagcacctg cagaaccacc aacaaacaat
    34501 acagtcggca atttatgatt aaagtggctt tgaatatcca ccaattcatc tggttctgga
    34561 tttttttgat ctgaaacctt ggtcactgct cccacatgct caaccttaga caaactcgaa
    34621 gcttgctcaa aggttgaata catcttagtc gcaaacttat aggcgatttt attggccaag
    34681 cccatagaca ggtcagattc gtgaataaag acaggcactc ctgacacacg cgcagcgata
    34741 acaggcggta ctgagacaaa gccccccttt gaaaaaaggg tctgtggacg aagtcgcaac
    34801 atgataaaga gcgattggac gattccccag ccaactttga agacgtccag catattttgc
    34861 caagagaaat agcgacgcaa ttttccagtc gcaatagaat ggaaggtgac atccaaacct
    34921 gacttaagga tttcttggtg ttcaatacca cgcttgtccc cgatatagtg gacttcccaa
    34981 ccatcttcga tgaacttggg cattaacaaa agattgaggg taacgtgtcc aaccgtcccc
    35041 ccacctgtaa agacaatttt tttcatatta ttcttttaac tccgctactg tgtcgataaa
    35101 gaggtcgcca cgtacttcaa agttagcata catatcccag ctggcattgg caggactaag
    35161 aagaaccaca tctccttgag tcgcaagctc ataggccttg cgggtcgcat ctgcaatatc
    35221 tgtcgcctcc acataagcga caccagcctt gtctgctgcc cgtttgacac gttctgcaga
    35281 ttgacccagg atgaccatct tcttgagtcc agtaatgtct ggcaccaatt cgtcaaactc
    35341 attgccacgg tccaaaccac ctgcaatcaa gacgaccttg ctgttgtcaa atcctgataa
    35401 ggctttttga gtagccaaga tattagttga tttactgtcg ttatagaatt taacaccctt
    35461 gatgtcatcc acaaactgga gacggtgttt gacaccaccg aaggctgaaa gagtttcctt
    35521 gatggtttga ttgtccacat cacgaagctt ggctacagca atagtcgcaa gggcattttc
    35581 cacattgtgg ctacctggaa caccgatttc attcgctgcc atgactactt caccacggaa
    35641 gtagagttga ccatcttcca gataagctcc atcaaccttt tcaagtgttg aaaatggtac
    35701 aacagtggct tctgtcttgg aagccaagtc ttttgccaag tcttgattaa agttcaagac
    35761 aaggaaatca gctgctgtca tcttgttctg gatattccac ttggctgcta catattcctc
    35821 aaataatcca tgataatcga tatgagttgg cataaggtta gtaataaccg caatctcagg
    35881 atggaattct tgaacaccca tgagttggaa agaagaaagt tccataacaa gcgtgttctt
    35941 gtctgtcgct atttgagcaa cctgactggc aggatagccg atattccctg ataaaagacc
    36001 atgttggcca gcagcagtca aaacttcccc aatcatagtc gttgtggttg tcttaccgtt
    36061 cgatcctgtg ataccaataa tcggtgcttc tgaaatcaaa taagccaatt ccacctcagt
    36121 caagactgga attcccttgg ccaaagcctt ttcaatcatg ggattgctgt aggggatacc
    36181 tggatttttt accatgaggg cgaactcttc atccaagagt tccaaaggat ggccacctgt
    36241 aatgaccttg atcccttctt ccagcaaaca ttgcgcagct ggattgtcct cgaatggttt
    36301 cccatcattt actgtcacaa tggcacctaa cttgtccaac aaacgagccg cagattcacc
    36361 agacttggcc aaacctaaaa caagaacttt cttattttta aattgatcta ttactttcat
    36421 gtctcgaact ccatttctac tcctactatt ttaccatttt tatggaaata aaaaagccac
    36481 aaagtgtgtt tgtgactctt tcttctaact gaatcttacc atatcatcta tgtgataaat
    36541 cggtaactcg aatgacctga tccacttgct cccaaatcag aggattgtgg gtcgcaataa
    36601 taatggtccg attcggattt tttaaagatt ctaggatgga aagtaattcc tcagagtttt
    36661 tggagtctag tgaagcggtt ggttcatctg cgaggatcaa aggtggatcc tttaaaatta
    36721 tcttcgctag tgcaacacgt tgtgcttctc ctcctgataa ctcaaatata ggttgcttca
    36781 aatccaaata agagaggttt acacggttta gagcttgttt catcaaagag attttctctt
    36841 tttccttcaa ctttttacca actaaaccca gattgagatt ctctttgacg gtttggcttt
    36901 caattaagcc aaaatcttga aataagtatc ccaagtaatc tctaaagaaa acagaaggct
    36961 tgatgtcctt aagagaagtg ccatcataga tgatttgccc tttgtcatat ggctctaatc
    37021 gtccaatcat attcaagagt gttgtcttac cacagccact tgtaccgatt aaggcataaa
    37081 ttttcccacc ttcaaaatga agattcgtat ctgaaaatag ctgacggctt ccaaattttt
    37141 tagatatatt ctttagttca atcatcctat tttcctttca taattgtcat agaaacacga
    37201 gattctttct gcgcttgacg gtaaagcgtc aaaactgcac tagctagaaa gaccaataaa
    37261 gtgagcaagc caatcaccaa gtctcgactg cttaaaataa agagactagc accaaataca
    37321 aaactggcaa attggctaac catatactga gcatgtgttt caaaaaatcg taaacctgaa
    37381 attcgtttaa tcaagatatc tcggcggaat tgctcgaaat atagaagatt gacagaataa
    37441 aagagtaaca aggaactggc tattccaaca atagctccta ggattaaagt tgctgtttca
    37501 gtttgaactt cattataacg agttagataa acacttcttc cttctttaag ataggatact
    37561 tgctcataaa ttcctgcatt tttcaagagt ttaatcccac tctcatatcc tttgataaag
    37621 agttgttttc cagcattgat agaccaacta gataaggata taaaactatc acctgtagaa
    37681 gtcggcgtga ataccactaa aatcggatca gtcaaatact gagtagatac gggattctca
    37741 ccgttattat aaacaaaccg cttttctccc attgaaagat aactaacgtg cgctttcatc
    37801 tcataatcca aaggagcact tgcctcctca ccagattttc cataataact caatctttct
    37861 tcaaaaactt tcttaagttc tgcttctcga gagcgcaaat gttctgggag caagaggata
    37921 aactcacctt tttggagatg ggctaacttc tgtttggtct cagcatctac cacgaccttt
    37981 tccttgtcca aataactggg actaacatag agcgtattag catctggact ataggtatcc
    38041 agtgtctctc cctcttcatt ttttccttgt ggattggcaa aatggagcag attatccttt
    38101 acataaagag cttgttcttc ttcgattgct tccttggcaa aggcatacca cttgctctga
    38161 ttttctgtat cttttcctct atcacctaag ccaaaggaaa tctggtaata gtctgctcta
    38221 tcctgccatg cttgttttga aatttcaagt tctttcaatc gttggtaaga cgtcaaacct
    38281 gtcttaacag cgtagcctac tgtaaaaaca gctactaact gacacaatag ggttaaagcc
    38341 atcaagcgtt taaggggtaa tcttccctta ataacgggaa ctaatgcttt gtaactcaaa
    38401 ctcattaggt aaaggagcat tagtaaaatt gaaatcgcca ataaaaacaa cagatagaaa
    38461 ctaatcccaa aaccataggt ggctaacaag ataggataaa acaaaccttg actaaaaaga
    38521 acgactcccc cacctaggaa ggaaaggagg gctgatagaa ggagccattt gatatcagta
    38581 gataaagaat gccccatgat ggataagaga gtctgaccag aaaagagttt tatacctgct
    38641 gctctcattt ccttaatccg agtgataatc actaaagcaa agaaagataa gccaaatatt
    38701 gctaaactaa ttaaaataag gggatttagt aatattcgaa aagcaagaaa atagggcggt
    38761 atctttcggt cagcacttgc tttataaccc aaatctccta atttatcggc aagcttttct
    38821 ttcgtcaagg agcctgacaa aaggagataa ctatttagcg gatcactacg ttcacgactt
    38881 tcttggctag cttcttggaa ttcttttggt aaagttccct gaccataagt tgcataagta
    38941 aagtgagtcg tcccatcctt actcggctct acaattcttc tagctattaa actctgttct
    39001 gagtttgcaa aattctccaa ttcctgttca aatacctcac gcgtcggttc ctgagtatct
    39061 tttttgacac gaagtaaaga aacggaatca tagcttgcat ataaatattg tggcgcacgt
    39121 aagacaataa tccaagcaag gaaaaagctg agaaaaaaag ttgataataa tatgaatagt
    39181 ttcttcatag tagactcctt gtaaacaaaa ttccccctgt aatttcttac aaggggaacg
    39241 atttaaatca atgaacgatt agtcataatc acagtaaaat gctacttgtt ctccccattt
    39301 agtccaaatc catgcatagg aggtttttcc agcagaagct tctcctttat ctgaatgact
    39361 attccatcta cttacaagag aagaataatg atatttttta ccatgatagt aatttgaaaa
    39421 agcccaacca cctcctgaac cttctccata tgtccatact cctccatctg gatattgtac
    39481 agcagctgat gcagctccca ataatgtaaa atttgaaata agagctagag caagtaatct
    39541 atgttttttc gttttcattt tattttttct ttcaaaaaaa gcacaccttg agcaacaatg
    39601 caacaaaata aatcctcctc tatcttttat tgaaaccgct ttcttatgtg ataagaataa
    39661 cttttttatt atttgttgtc aaggaaaaaa tcgaattttt tagatatttt actatattac
    39721 ctctgtgaat aatattatat agtagtttta tttcaaaata atatgcaacc agtactaacc
    39781 aaatataaaa tagatgccat taacgaattt tattcaagtt tttcccattc atactataca
    39841 agtaaaagag atggtgttaa ctaaaaagca attcaaacta ttgtaaaatt cctagcaaaa
    39901 agagagccga aactctcttt tttatcttct tttacttttt ttgactggca tgagtgtgat
    39961 gtctctaaca ctaaagtaag ctaggatcaa catggctatt gctaggaata tttctgttgg
    40021 taattgaaaa attttcagaa aagatagaac caataaaatc aagagtgcca ctaaaataca
    40081 taccatagcg acgatattga cagtcccttt aatgctttct ggtgtcgcaa atacatagag
    40141 taggagcagt aaaattccta ggactaaata gaccatcttt ctctctttct agctcttatt
    40201 cagctgattt tttcttcttg ttagctttct cacgctctgc tttgttaagg atttgtttac
    40261 gcaaacggat agactcaggc gttacttcca tgtactcatc gtcgttcaag aactcaagag
    40321 actcttcaag tgtcaagata cgaggcgtct tgataacagc tgtttggtcc ttagtagctg
    40381 aacgaacgtt ggtcatttgt tttgccttcg tgatgttaac tgtcaagtca ttttcacgag
    40441 agttttcacc gatgatcatt ccttcataaa cctcagtacc tgggttgaca aagatcgtac
    40501 cacgttcttc gatagacatg attgagtaag ttgtagcctt accagcatcg atagaaacaa
    40561 gggcaccacg gtgacgtcca ccaatttccc ctggaatcaa tggcaagtat tggtcgaagg
    40621 tatggttcat gataccgtaa ccacgagtca ttgacaagaa ctcagttgag tatccaatca
    40681 aaccacgcgc tggaacaagg aagaccaaac gagtttgacc attaccagtt gaaatcatat
    40741 ccaacatttc acctttacgt tcagaaaggc tttggataac agacccttgg tattcttctg
    40801 gagtgtcgat ttgtacacgt tcaaatggtt cacatttaac accgtcgatt tcttttacga
    40861 taacttctgg acgagatact tgaagttcat agccctcacg acgcattgtt tcgataagga
    40921 ttgacaagtg caattctcca cgtcctgaaa cagtccattt atctggtgaa tcagttgggt
    40981 caacacgaag ggaaacgtct gtttgcaatt ctgcctgcaa gcgttcttcc accttacgag
    41041 aagttaccca tttaccttct ttaccagcaa atggtgagtt gttgaccaag aaagtcattt
    41101 gaagagttgg ctcatcgatg tgtaggattg gaagagcttc tactgcatct gtcggagtga
    41161 tggtttcacc gacaaagatg tcttccatac ctgaaacggc aatcaagtca cccgctttgg
    41221 cttcttggat ttcacgacgt tccaaaccaa agaaaccgaa gagttttgta acacggaagt
    41281 ttttagttgt accgtcaagt ttagaaaggg taacttggtc cccaacctta actgtaccac
    41341 ggaagacacg accgataccg atacgtccaa cgaagtcatt gtagtccaaa agtgacactt
    41401 ggaactgcaa aggctcatct gagttatcta ctggagctgg gatatggtcg ataatcgtgt
    41461 caaagattgg tgccatagtc gcttcttggt cagctggatc atctgacaat gaagaagttc
    41521 cgttgatcgc tgaagcataa accactggga aatcaagctg gtcgtcatct gcaccaagct
    41581 cgatgaaaag ttccaagact tcatccacta cttctgctgg acgagctgat ggcttatcga
    41641 ttttgttaac aaccacgatt gggacaaggt cttgttccaa ggcttttttc aatacgaaac
    41701 gagtttgtgg catggttcct tcataggcat ctacgaccaa gacaacaccg tcaaccattt
    41761 tcatgatacg ctcaacttct ccaccaaagt ccgcgtgtcc tggtgtgtcc ataatgttga
    41821 tacgagttcc gttgtaagca acggcagtat ttttagcaag gatggtaatc ccacgctctt
    41881 tttcgatatc gtttgagtcc atagcacgct ctgccaattc agtacgtgca tcaagcgttt
    41941 ctgattgttt caataattcg tcaaccaggg ttgttttacc gtggtcaacg tgggcgataa
    42001 tcgcaatgtt acggatatct tctcttaatt ttgtcatgat ttcctctata atattcaaaa
    42061 tttattttct aactgaacga ttataccata atttcaagta aataacataa ctcaagcaag
    42121 tgtaaatgtt ttcactctgc ttttcttttc acgtcaagcc ttttcaaagc gagcgactta
    42181 tgataagata ggcacagtat gcgtttagat aatttattag cccaagaaaa aatcagccga
    42241 aaggccatga agcaagcact cctcagaggg gaaattctag tcgatggttg cccagcccgc
    42301 tccctagctc aaaatatcga tacaggacta caagaactcc tttttcagga tcgaatcatt
    42361 caaggctatg aacacaccta tcttatgctt cataaacctg ctggtgtcgt tacagccaac
    42421 aaagacaagg aacttccgac cgtcatggac ctgcttccat ctgacatcca gtctgacaag
    42481 ctctatgccg tcggccgact ggaccgagat acaacaggac tccttctctt gaccgataac
    42541 ggtcccttgg gcttccaact cctccatccc caatatcatg tcgataagac ttaccaagtc
    42601 caggttaatg gacttctaac acctgaccat atccaaacct ttcaaaaagg aattgtcttt
    42661 ttagatggca ctatctgtaa acctgcaaga ctagagattc tatcagcaag tccttccttc
    42721 agtcaagcct ctatcaccat ttcagaagga aaatttcatc aaatcaagaa aatgttcctc
    42781 tcggttggtg ttaaggtgac tagcctcaag agaatccaat ttggggactt cacattgaac
    42841 ccagatttag cagaaagtaa ctaccgccct ttgaaccaaa aagagttaca aatcattaaa
    42901 aactatttag agatgagtcg ataaaacaaa aaaagcttta aaactaaagc ttttttcttt
    42961 tatttaccga aaaattaagg cgattgctac aatccagtta actacagaaa tcacaattcc
    43021 taagatatta agaatctttt ctattttata gtctaattgt gactcttttt ggtatgaaat
    43081 agccaagacc aatcctatga tacccaaaat caggcctaca attggaaata acaaaccaag
    43141 aataatcgac aagataccca caaaaagtgg atttttcttc ttttctttta tgttctaaga
    43201 actccttaaa ttttatacaa attaattata ctataaaaca atagcttcat cctatcattc
    43261 gactaatttg gaaataaggt tagctagtct tcactttccc tttccaagaa tccaagccat
    43321 aagaaaggat ataaatctca gaaaaacctt gttttttcaa gtaaagagct gcatttgtaa
    43381 ctcgttgcgc acgttggttt tcgtagagaa ggacaggttt atctttacga agggctgcaa
    43441 gactagtttt caactgactt gaaggaatat tgcgtgcacc aaggatatgt tttctgtgga
    43501 attctgctgg gtcgcgcaaa tcaatcaatt gacccgtacg aatcaaggct tcaaactcct
    43561 cattgtccac aattttagcc gcacggcgaa tacgaagata gttaaagccc atccacgcca
    43621 acattgctag tataagtgcc cacaaaatcc aagtaaccat tagttctttt ctccattttt
    43681 ctcaatataa tccaattcta ccttgtgctc tctgcgaaga actgcttctg cctctagata
    43741 gtctaattta tccatcaacc ctgcatcgta aatccgagat agttccaact tcatcagttc
    43801 aatatcatat aagcgttttc ccatgtaaac aataatacca aatcgtttga ggaattgctg
    43861 cacatcatag aatgttttca taagactcat tctagcaaaa ttttgtgttt ttttcaagaa
    43921 gagactcaca caatgctcct tattttccta tcttctttag cgattctaag gcaagtatgg
    43981 tacaataaaa acatgagaat tcaacaatta cattatatta tcaaaatcgt cgaaactggc
    44041 tccatgaatg aggcagccaa gcaactcttt atcactcagc caagtctctc caatgcagtg
    44101 cgagatttgg aaaatgaaat gggcattgag atctttatcc gcaatcccaa gggaatcacc
    44161 ttgacccgtg atgggatgga gtttctctct tatgcccgtc aggttgtcga gcagacccag
    44221 cttctggagg aacgctataa aaatcctgtc gcccaccgcg aactctttag cgtttcgtct
    44281 caacactatg cctttgtggt caatgccttt gtctctttgc tcaagaaaag cgatatggag
    44341 aaatacgaac tcttccttcg tgaaactcgg acttgggaga ttatcgacga cgtcaagaac
    44401 ttccgcagtg aggtcggggt cctcttctta aacagttaca accgtgatgt tttaaccaag
    44461 atgctggatg acaatcacct gctagcccac catctcttca cagcgcaacc gcatatcttt
    44521 gtcagcaaga ccaaccctct ggcaaagaaa gacaaggtga aactgtctga tttggagaat
    44581 ttcccttacc tcagctatga ccaagggacg cacaactcct tctacttttc agaagagatt
    44641 ctttctcaag aacaccacaa gaaatccatt gtggtcagtg accgtgccac cctctttaat
    44701 ctcttgattg gtttggatgg ttataccatt gcgacaggga ttttgaacag caacctaaac
    44761 ggagacaata tcgtttctat cccactggat attgatgacc cgattgagct ggtctatatc
    44821 cagcatgaga aaaccagcct atctaagatg ggcgaacgct ttatagacta tctcctagaa
    44881 gaagttcagt ttgatagttg agaaatgata agaaccaata tgtaggctag caacaacctg
    44941 cacattggtt ctttttactt ataattaaaa gtttcccctg ccaacttatc agctagctta
    45001 ggaaagaggg tataaaactt atgagctagg ttcaacaaaa tcgggagatt gagttctcgt
    45061 ttgttttttc ctataatctt gacaatcttt ttagccactg catctggttc tagcaggaag
    45121 cgatcaaccg atttaagata agttccatct gggtcggctt ggtcgaaaaa tcctgtacgg
    45181 attggtcctg gattgactgt tgtcacatag actccatagg gcataagttc gagtcgcaga
    45241 gcatttgaaa aaccaatagc cgcaaacttg gtcgctgagt aaagactaga cttgccagta
    45301 gctattagac ctgccatgct gacgatgttg atgatatgcc ctttgctgct ttccttcata
    45361 cgagccgcaa ggtgacgaga cagattcatc agggcaaagg tattgacctc aaacatctgg
    45421 tgaatatctt tatcagcaat ctggtcaaat ccctcaaaaa tcccgtaacc agcgttgtta
    45481 atcaagacat caatcttgcc atagcggaga taaagatcag ttaccagagc ttctagggct
    45541 gaatcgtcgg taatatcaat ttcaatcaat tctgcatggg aataatttcc gtagagttgg
    45601 gctaattttt ccttatttct accaagcaag atgagttggt cattgggcag gagtttgacc
    45661 atttcttgag ctagaccacc gctagctccg gtaatgagaa tagtaggcat acttatcctt
    45721 tctgtgactg ctagatttcc acttcttcca agtctttgac cacatggaca ttttcaaaaa
    45781 ttgtggcagc gtctttcttg agtttgctaa tatcttttga gaggaaacgg gcactgatat
    45841 ggttgagtag gaggcgtttg gcacctgctt ctaccgctac ttgtgcagct tgcatattag
    45901 ttgagtgacc atggttacga gcaatttttt catcaccctt gccataagtg gactcatgaa
    45961 ctaggacatc tgcattgaca gccagacgca cactggcacc cgtttttcga gtgtctccta
    46021 aaatagtgat aatcttacct ggacgtggcg ctgagatata gtctgctgcc ttgatttcag
    46081 ttccgtcttc caaaacaaga tcctggccgt ttttgatttt accaaaaagc gggccgaacg
    46141 gaacaccagc agccttgagt ttttcagcat ccagcgtccc ttctagatcc ttttgcatga
    46201 cacgatagcc aacacagaaa atagtgtggt ccagctcctc tgcatacaca gtgaatttat
    46261 cggtttcaag aattttaccc agagaatctt ggtcaaactc atggaaatga atgcggtagg
    46321 gcagacgaga acctgacaca cgaaggctgg ttaagacaaa tgacttgatt ccttgaggtc
    46381 cgtagatttc caaatctgtc tgctcttcat tggcctgaaa ggcacggcta gaaaggaaac
    46441 ctggcaaacc aaaaatgtgg tctccatgca gatgggtaat aaagattttg ctgaccttac
    46501 gtggtcgaat tgtggtttcc agaatgcgat tttgcgtacc ttctccacag tcaaagagcc
    46561 aaacttcgtt aatctcatcc aaaagtttca gggcgagact tgaaacgttg cgggctttag
    46621 agggctgacc agcccccgtt cctaaaaatt gaatatccat tcgatacttt ctaattaatc
    46681 aatatataac atggctgtgc ggttttccga tcggaaatag cgtttgccag aaaaagcagc
    46741 agcttcttgc aataaatcct cttggctgta gcctttgaga cgttttcgac catcagccaa
    46801 tctttccaaa tcagtcaaag ctgtgagact ttctaggctg ataacttcct cgtcctcgac
    46861 aagcttcatg taaatcttac cagactcttc aaagactaat tgatggggga aaatttgcgc
    46921 aatttcaaag agcaagtcat ccgagatttt ctcctcattt tcaaagaaaa tccgaccaag
    46981 gccgtcactc tcataacaaa aaccaaagga tttaccagac agattaagcc gaataaaagg
    47041 cttattttct agagtgaaac ttggctcagt attgtaaaga ttcagttcct gactgagttc
    47101 tgcaaaataa tccgtcgcag cctgaggact ctttttctga tagagttctg caaagtaggc
    47161 attaacaaca cttggcggag gtgtaataag tgttaactgc tcctgatctg ttttaccagc
    47221 tagaagctga tccagataga ccttgtccag acttgtataa cctccatact ttagagccaa
    47281 agttttaata tcagtcataa aattcttcta acctccattt atttttctcg gaaatgtagc
    47341 ctgtaatcac ttcgccgtct tcctgataat cacgttcttc cagaattgca acactctcta
    47401 aatcatgaat cttgtaggac tttgaaaaag gcactcgcag ggtaaatgct tcaaaaattt
    47461 ccttaatctt atctagcaat aatgcttgca agttttcacg actgtcctca gacttggcag
    47521 aaatgagggt atatggcgtt tgggtaggcg tgaaatcctc caccaaatcc gctttattat
    47581 aaagcgtcaa gttaggaata tcttccatgt ccaggtcttt catgatggag agaaccgttt
    47641 tttcatgctc ctcgtggtaa ggattgctag catcgataac atgaaccaga aggtccacat
    47701 gcttgctttc ttccaaggtt gacttgaaac tggacaccaa ctctgtcggc aaatcttgga
    47761 taaagccaac ggtatctgtc aaagttactt ggagattgcc tcccagatga atactcttgg
    47821 ttgtcgcatc cagagtcgca aagagctcat ctgcttcata ctgggtctta ctggtcaaga
    47881 tgttcatgat agttgatttc ccagcattag tataaccaat caaaccaatc ttaaaagtgc
    47941 tagactccaa acgtttttct ctgacagtcg cacgattttt ctcaaccacc ttgagctggc
    48001 gctcaatatc cgtgatttga ttgcgaacgc tacgacggtt cagctccagc tggctttcac
    48061 caggaccacg ggaaccaatt ccccctgcct gacggctgag cataatcccc tgaccaacca
    48121 agcgaggcaa gaggtatttg agttgggcta ggtggacttg gagcttccct tcatggcttc
    48181 gagcccgcat ggcaaagata tccaaaatca actgcatacg gtcaatgacc ttaacaccca
    48241 gaacttcctc tagattgaca ttctgccttg gggtcagacg gttgttgacg atgacagtag
    48301 tgatttcttc tgcatccacc ataagcgcaa tctcttccaa cttaccagag ccgacgaagg
    48361 tcttggaatc atatttttca cgtttttgtc tgtagctatc tacaacgact gcccctgccg
    48421 ttttcgctaa actagccaat tcttccatgg agaggtcaaa actgtccata ccctgcaatt
    48481 ccacaccaat cagcaggact cgctcctctt ttttctccgt ttcaatcatc taaaaactcc
    48541 tctatctggc ttaaaatgcg gtcttgtaca ccagattctc caatctgata aaaggtgacc
    48601 tgcatgcgat tacggaacca ggtcagctga cgcttggcaa aacgacgggt cgcctgttta
    48661 agactctcac gagcttcctc aaaggtctgc tctccacgga aataaggaaa gagttcctta
    48721 tagccaattc ctttagcagc ctgtacatta ggggaatggt caaacagcca cttggcctca
    48781 tccaaaagcc cagcctcaaa catcaaatcc actcggtggt tgatacgctc ataaagttga
    48841 ctacgttcat catccaagca gataatcagc ggttcataca agatctcttg attttccaaa
    48901 tcctgaccaa aatgggcaat ttctaaggca cgcatagcac gacgacgatt aaactgggga
    48961 atctcaaggc ctgcttgctc caccaaatgg gctaattcct catctgaata tggctccaaa
    49021 ctagctcgat aagctaaaat ctcctcatga ggagtctccc cacctaggtg gtaaccttct
    49081 agcaagctct ggatataaag tccagtccca ccggcgataa tggctagctt gccacggctc
    49141 tgaatatcct caatagtcat cttagcttct gaaacaaaat caaaagccga gtaagactcg
    49201 gttatctctc taacatcgat taaatgatga ggaacagctg cctgctcttc tggactagcc
    49261 ttggccgtcc caatatcaag tcctcgatag acttgctggc tatctccact aaccacttcg
    49321 ccattaaagc gctttgcaac ttcaatagct agagccgtct ttccaacagc agtcggtcca
    49381 acaatcacaa ttatttttgt tttcatcttt tttccttgaa aaattcccat tttttcgtta
    49441 ctattattat aacacaaaaa ggtcagtcag aaaaatgtga cctcttgagg aggctggctg
    49501 attgagaata taaaggagga agactcatgg ctaaaggatt cgctaaaggt cttgtaacag
    49561 gtgtcgcagg aactgtcgct gccgttgcag gtgcagtata cgcatttaaa aagaaagtaa
    49621 tcgaaccaga agagcaaaaa gcagctttca tcgaagaaaa tcgtaaaaaa gcagctcgtc
    49681 gccgcgtatc acgttaagaa acaaaagaag ttgggattat tctcaacttc ttttttctat
    49741 tcttttaaat agctaggtca aacttcaact gtggcttaac agggtcataa tccaccaact
    49801 caaaatcttc tgctttgata tcaaagaaat tagtcccatc aggaacattt aaaaccaagc
    49861 gtggttggca gtttgacggc tcccgacgga gcaattcctg agcttgttca aattgattat
    49921 catagatatg gaggttgttg atgaaataga agaacttccc aaccttccaa ccaaaatgtt
    49981 tggcaatcat catctgtaaa gccacatact gcatagcgtt gatgtggtgg gccaccagca
    50041 tatcattgga gcgctgggtc aaggtcgcat ccagatagat ttccccatca acacgccgga
    50101 catcaaacat ggtctgaaag gcgcacggga gcagcccatc tgtttcttcg aaagcttggt
    50161 aatcccagag cgaaataata ttgcggcggt tccaaggatt ggtttccaac tgtttgagaa
    50221 gcttattgat aatgtcgtgt ttcttaacaa cggcaccata gcgctcacca atggttcccg
    50281 tgtctccaac ttcccagtca ttccagtagt gaacattgta cttgtcatta agcacttcta
    50341 agctatttga ctggtcttgg taaatccaga gaacttcttt gatggcggat ttgattgcaa
    50401 tgggacgcaa ggttgtgata ggaaattctc ctttagataa gtcgtactcg gaaaaggcac
    50461 cagttacata cttggaatta gcaacagtcc catccttgta cttaggacga gcctgctctg
    50521 agaaaacacc ttcctttaga atgcattcaa tattctcttt aaaaatcgta tctgcttttg
    50581 tcatttcgtt tcacctcatt cattgtccta actagtatag cataaaaaat aaaagaggaa
    50641 cattactaac tctaggttag cattttcctc tctcattatc ttattgcaat acaagtgatg
    50701 ctgctccgat aactccagcg tcatttccta gagttgcaag agctaattta gtagatgtgc
    50761 gtacttgtgg gaaactattt tcatcgtaaa ctttttgaac accttgtaga aggaattctc
    50821 ccgcagctga cacaccacca ccgatgacga ttgttgatgg gtttaggatt gaaccaatgt
    50881 tagcacaagc gattcccaag taacgtgaga agttacggta aacaatcaaa gcaaggtcgt
    50941 ctccttcttt tgcgagatca aagacagtct tagcagttac ttcttctccg ttatcaatca
    51001 agcgtttcaa ggctgcatcg ccttcgtatt catcggcata gcgacgagtc aagttgacaa
    51061 tccctgttgc tgaagcaact gtctcaaggc agcctttttt accacaagta catgagattg
    51121 gttggtcaaa gtcaacagtg atatgaccaa gttcacctgc tgcaccagca acaccatgaa
    51181 gcaatttgcc ttctgcgaca ataccaccac caacaccagt accgaatgtc ataaagacaa
    51241 cgtctggttg gttatctcca gcacccatcc agcgctcacc aagagctgct acgttggcat
    51301 cattatcgat gaaaaatgga atgcccaaag ctttttcaat cttttgtttg attggttgaa
    51361 gggttttcca gttcaagttg taggcaccga taacagtccc tttgtcacgg tcaaccacac
    51421 ctggtgatcc cattccaatg ccttggaagt ccgctgctgc caatccaagc aagtccaaac
    51481 gatgttgaat agactcaatc atatcatcaa cgatatgact tccctcatcc aaaatgttgg
    51541 tcttgattga ccattttcct tggatttctc ctgctgttgt taagattgca aatttgatag
    51601 aagttccacc aaggtcaatc ccaataatct tttgactcat catattctcc tttttcattg
    51661 tgtagtaatt gaaaatgctt acagtactag tatatcaaaa tccattcact tatgcaaagg
    51721 tttgcgtaaa tgaattataa ggaatttttt cgcctaccag tatctgttaa tcatctaaat
    51781 gatcaatggc atattgagct gcatcatttg aaaatttatc aaaatcagaa gttaattgtc
    51841 tatacatacg tttttttgac atgtggaata acgaattata actttttgcc tttcctaaag
    51901 cagcagaata ttcactattg ctatcattac tagaagaagc tgtacttgct tgaccttcct
    51961 tccaaactcc gtcagcgcca acataataac gtccaccatc aacccattca ttgacagcca
    52021 ttttaccatc cgattttaga tagtaatttc cttgccatgt actgtaagca taagaaccat
    52081 ctgatgtcaa ataataccaa gcttgatagg tggcatcata aacccattca cctttagcca
    52141 ttttaccatc tgatttcaaa tagtagtttc cttgccatgc attgcgagca tatgaaccat
    52201 ctgatttcaa gtaataccat gcttggtaag aagaatcata aacccactca ccttgtgcca
    52261 ttttaccgtt tgatttaagg taataagctc cttgccatgc attttttgca taagaaccat
    52321 ctgatttcaa ataataccaa gcttgataag aagagtcata aatccattca ctctgtgcca
    52381 ttttaccatc agctttcagg taatagcttc cctgccatgc atttttcact agatttccat
    52441 ttccatcaaa gtagtaccaa gcgccgtcct gcttaaccca accacttgtt gttgctgaac
    52501 ttgtgttgat ttgaatagcc gttgactgtt ttgctttaaa agcaccctta ggagcatttt
    52561 tcaattcgca agccacacca tcatgatcac ggtctaactt ggcagaataa ccaggttctc
    52621 cctcgtgaat atccgaatag ccattcgccc aagcttcctt acagctcgaa aaatggatgt
    52681 tttcttccgc caaaactggt tgtgaaaaca aggctaaaat tggcaacgtc accagactca
    52741 tttttaaaaa tagacgttta ttcatttctt tctcccataa ttatgatatc gatttcaata
    52801 ttattttatc aaacttattt cagcaattca aggaaacttc tggtcttttc tacaaactcc
    52861 tttggttttg ccttattcaa gacatgaggg ccataaggaa tgatctgaaa ctgcgaatct
    52921 gttaacagtc tatggagagc tttcatagaa ctaagattcg gtttatcttt gctgccacaa
    52981 attagtaagg ttggataagg gcaagttcct gctatatccg ttaaatcaag tgtcttcaac
    53041 tcctcagaaa ctccgaccat aagagtcttg tctgctccct gtttttcaaa tactcttttg
    53101 ggaagtagtt taaaaatcag caactgaaga taaaatagga tattccctgc taatttaagc
    53161 gggcatcctg acagaatcaa atctcgaaga tttggtaaat cgtaactgga aagttctagt
    53221 gtcagggcag cacctaagga caatccaatc aaaacaaaag gttctgtctc ttgagctagg
    53281 tgctgataaa ctcgctcttt agcttgttga tagttactaa ctccagaagg aaataactcg
    53341 atagcctcag aaggataatc tgtcagtaga ttccgaactt ctttccaaga ctctgctgac
    53401 tgccctaacc catgcaaaaa tatcaatttc atctagttct cctcaaggct tagttcatac
    53461 aagcctctca ctgcattaca gccgtaaata gcttctgctt gggttaaatc tgccaaggtc
    53521 aagactttct cttctacctg tcctgtttct agcaaatgct gacggtaaat tcctggcaag
    53581 attccaagtc ggataggcgg tgtgtagagt tttccagcga ttttcagaac caaatttcct
    53641 atagaggttt caagcagttc tcctgactta ttgtggtaaa tcttctcttg ttctcctagg
    53701 ctcaaatgcg atcggtgagt ggttttaaag taggtaaagg attgattcaa agcagcttcc
    53761 tgaagacaga cttgggcctg acaaaagctt gtactgagag gggttaatac ttgacgattg
    53821 acttctatct ctccagattt gctaaggctg attcgcaagc ggtaatctcg attagcttca
    53881 caatcctgac actcttcctc aatcttgtgt cccaagtctt ctgcatcaaa aggaaaggca
    53941 aaataacgac tggcttttct cagtctttcc agatgttgat cttcaaacag caggttcttc
    54001 tggctgattt cccctgtcgt aatcagttgg aagcgggctt gtttacgata aagaactgct
    54061 gccttttgat gaacctctcg gtattcagat tcccatgtgc tatcccaagt aatccctccg
    54121 ccaactccat aaatggcttg acctttgtga agttgaatgg tacgaatggc cacattaaaa
    54181 atccgtcgtc catttggaag caagagacca atcgttccac agtagactcc acgcggttga
    54241 ggctccaagt ccttgataat ctccattgtc gcaattttcg gtgcacccgt tatggaacca
    54301 caaggaaaga gtgagcggaa gatttcaaca aggtccacat cctctcgcaa ctgactcttg
    54361 atggtcgaag tcatctgcca aacagttgaa tactgctcta cctgacacag acgctccacg
    54421 tgctcgctcc caacttcaga aatacggttc atatcattgc gcaagaggtc cacaatcatc
    54481 atattttcag agcgattttt gggatcctgt tccaaccaac tggcctgttc aagatcttct
    54541 tggtcagtta ccccacgctg agtcgtcccc ttcattggtc gtgttgtcaa ctcgcgatca
    54601 ttttgctcaa aaaagagctc tgggctcatg gaaatcactg ccatctcgtc atgttccacg
    54661 taggcattgt agcccgcctc ctgctctacc accatacgat tgtagatggc aaaaggattg
    54721 gcacttaact tttgcttgag ttggacggtg tagttgacct gataggtgtc tccctgcctc
    54781 aagtgatggt gtatctgggc aatggccttt tcatagtctg ctgcagacgt cacttcctgc
    54841 caatttgagg gcaaatcaat atcctcataa gtcagaggaa taggggaggt ctctacccta
    54901 tcgtgaacag taaagtaaag caagtactcg cccagtagag gaaccttgtg aactgttaat
    54961 ttctcctcaa aagcaggtgc agcctcgtag ctgacatacc ccaccacata ataaccttgc
    55021 tcttggtagc tttccacttg tgccagcaaa tctgccactt cttctacatt tctcgttttc
    55081 aactctttaa taggctgggt aaaggtatat ctctccccca aagtcctaaa atcaatcact
    55141 gtttttctat gcatacttta agtatagcat aaaataagaa aaccctcatc cgcaaagcag
    55201 atgagagatt tcgattatct aaagatagaa gttttaaagc tatctgtttg ttgaagaagt
    55261 tgtctgaaaa cttggaattt gaagtttctt gtttccctct catctaactg atttttcttc
    55321 aaatctcttt caacagcctg cttaaatcct tcttgcaatt cttcaaaggt gctatatgtt
    55381 ttttgattga tagtaacagg acgaatacct ttagttttta actcttctac tactttctta
    55441 aaatatccct ttttaaatgc ttccatagtt aaaaattccc ctttggaaat cttagaaata
    55501 ataaagttat cactaagtcc agcatgacct tcatctctag atgcttgctt aaatttatta
    55561 gaagcatatc ctagaacacc ttcttcaaaa ccatagtagc cccacatacg gaaagtatta
    55621 tgtttaaaca tcaaggcacc tggtgaacct acactattct ttcctccacc ataaatacca
    55681 gtcatataat ctatcgcaat ataacttgtt tcaaaatcag ctggattata ggtattattt
    55741 cctacagctc tgtctgacat taatccttga tcaactaaat catcaacact agaaacagaa
    55801 agtttttctt tctcttcagc agtcaactga cgaaccgtat catactgagc tgtttgacta
    55861 acaaccttag gttcaacttt tttaaaccat ttagtaatag cttctttacc tttagagata
    55921 actgcatctc cttccaagta gtccaccatc atgagagtat cgttataatt tttcatataa
    55981 ctatctaact ctttcctatt ttcaaattga gttggggagg cattataaat tagatcacca
    56041 tcgttttttc tttcaaatgc catattgaga cccagtgccc cccaacccgg ctgacctgga
    56101 acaggagact ggaataatcc ctgagcataa gcttcaggtc ccatattttc acgtctacca
    56161 taccctccta agtaaatcca agtatcatta acgtgagtca attcatgagt gaagacagat
    56221 ataccatact cacttaatac atcaaacacc tcataattaa cccgatttct tcctccagca
    56281 tgcgcaccat aaccatggta agcataccaa cctcccatag gaccacctac aagattaaag
    56341 aattctcgag ctggggcgta atctcttcct tttctatcta cagcattctg gtctacccat
    56401 tcacttcctg ggatgctcag tccttcccaa acagcagtaa cattctcttt aaccatttta
    56461 cctttgatat tatcaggtaa aatcttatac caagtatcaa catggtttct atgagcagtt
    56521 gctacatatt tcacccactt atcaaaatct tcatttttcc aattagggcg tttttcacgg
    56581 ctgacaaatg tcatagtact atagttcgat aaaattgcta aatgagtatt cttcaacgtt
    56641 aagagaggta ggatatatcc ttgataatac ggtgcggtta aattatcgta aactcgatat
    56701 ttggcatctt taatctcctc tactaaggat ggacgttcct caaattgaat ataatcctta
    56761 gtcgtttctt taaaccattc ccctgttgtt tgataattag tcaacaaaga gcgattgtag
    56821 tctaaataag tcaccaaatc cttctgcttc gtttcgctag caaataactg cttgaacgtt
    56881 tctgcatttt ctgaaccttt taatctattt tctccagatg atcctagtcg gattaatcga
    56941 tctaatagat caatcttttc accatggaaa gttggtttaa agagcatcag ttttttaata
    57001 ttatagtctg agaatttaac atcataataa cgattgatat aagtcaaagc aagcaatata
    57061 gccgtcttat tatccatgat tttttgtcgt aaagcagcga cagctccact agattctcca
    57121 ttgatgtgca accactcatt ttcaaacatt gtttttacaa aggtaggcaa ttgtgtttta
    57181 acagcatcta atgactcatc taagaataat ctcttagttc tattcaattt gttagcatta
    57241 tctttatcaa tacctagaac ttggtaagta gactctgtat acaattctac ttttttcaat
    57301 tcttcaacaa ggttatttat cagtgacgaa tctagtggat gtactatatg ttctgatgta
    57361 tacaccacat ttaaatcttc aacctgatat tccggtaaat tagttatcga aaacttacca
    57421 gtagaggtta ccttatatcg cttctgacta ccatcctcaa aatgaagcat gatagtatca
    57481 atatcactgc catctacaac gaactctgtt cctttcaacc ctacaatcga tttgattttc
    57541 ttagtcttca atatttcctg ttcaggagtg agagcatttc cttcatgaac aataaattct
    57601 ttattgtaat aaggagtaaa tttagtcaag ttctggtaaa ttaattggtt ttgggcttga
    57661 taatcctgta tactttcaaa ttgatcagta tttttccaac tttcattgag tctgtctacc
    57721 aaaagacttg agtcactcat caagttggga gctgtaatat tataagaagc aactttttga
    57781 tttgcttctt cctcagaaat acgcgtaaat ttagaatcac tacccgaatc gcctgagctg
    57841 atgccttgaa caccaaaaat attactaatt tttttcataa accaatcata atttaaatca
    57901 ccatctgatc caaataattc tttccctttg gtcacttttg catagctgac aacattatca
    57961 attgctccat aaggccagac tgtagaagag gctcctccag cttgccctcc ttgcttggtt
    58021 tctaatgttc ctttagcaac tgactcagta agtctacccc aggttcccca accaccactt
    58081 gcatctgcgt ttattccatt tactgcaaca agcatgctag aattagatga tcgatgtacc
    58141 tctatatctg catttacata ggcacgttta acacgagata agatatttct acctgcaata
    58201 cctgctgtaa tagaattacc acctttagac ttaatctttc ctgtaaagga tacattttca
    58261 atttcggaat taccttcaag attattaact aaaccagcta catgatctcg accctcgaga
    58321 taaccttcaa cattaacatt ctcaattttt gtcttatctt tgattactct tgcaattgtt
    58381 gctacgttat ctccttgatt gctatctggg aataccatat tgacatgctt gaaatcaata
    58441 tctttcacga ctcctgattt tatagtatca aacaatggat attctaagtc aaagatcgag
    58501 tgtctaacat tatcatttgt accaagtagt tttcctttaa attcaccttt gatataagat
    58561 tttccatttc catccggttt tacattacgc gaggaaatat ctctccctaa aataaacgta
    58621 cctgtaggat tagatgtcat agctgaaatc aagtctttaa aatcataata aatatcacca
    58681 tcatgaggga taactctctc catgtaatag tcaaatccct tagaaagact gccatctttc
    58741 ttacgaacta ctaattctgg tgtatctgca tgaattttaa agattttttt attttcaaca
    58801 atctcttctt ctatagagct aacggctaac acagcatcct tagacgttga cgatgtaact
    58861 tttaagtata atttactcaa atcggtcggt ttatcagaca agtgtgtaac ctgactttct
    58921 tgaccatttt caaatttcat cagagagact gtctggatat ctttcaattc tagtttctta
    58981 agattcagct gaattagttc ttctgaaata ctctccgtct catcatcatt tcctctgtta
    59041 tataccatat ccgtagatag agtgtattct ttgtagtagt ctagcttttc aaacaaagca
    59101 gttaaatgat tagttttaag attttcttct gttaaaacaa aatccttaac aacttcctct
    59161 ccttttttca gagttgcagt tattgatttt atttgagtat ttgctggatt ttccaaagta
    59221 tacgtgaccg tagcttttcg atctatgtct ctcttttcaa tagatagagt caaacgtggc
    59281 ttttcagaca attcaaccaa tttttccata gttgcagtta atttttcaac agcttcatta
    59341 acttcacttt gtttagactc gttagtattt acagattttg ctgctgtaag cgctgtttct
    59401 aactctgccc atgtttgatt tgtatagttc tctttatttt tcttggtagc tgtatcgata
    59461 gcgcttccca aagctgtttt gtcaacagat aagtcagcaa gggctgtttt caaacttttc
    59521 tctgcttcgt ttatttgttc ttgggtcgct gttccgttat cttttacttc ctgagcttta
    59581 tttttagctg tactcaaaac agtccaagat tccatgctga aatcagtttc agtttttccc
    59641 tgtgcaatct taagttgatt ttcgagttca actttatctg tatttaatct agaaattgct
    59701 gttttaagac ttgcagtctc agaatttact tcactttgtt tagcatctgt attagctgca
    59761 actttttcag cttctgtaac cccagtttgg aggttttgcc aacttctatc actgtaatgt
    59821 tcttttacct ttgtttttgc atctgcaatc gtattgttta attcagtttt atcaacgttt
    59881 agagcgtcaa tagccgtttt aagtttattt gtctcactat ttacctcagg ctgttttaca
    59941 ggctctgaag catagacacc ttttgcagtt tctaaaacag gtccaagatc attgtaactt
    60001 gctgtagaat aatcagtagg agaaactgaa ctagctttat caatttgatt atttaactca
    60061 cttttatcaa ctggttcttt agtaccaata ccctttattt tatcttctgg tttcggtgtt
    60121 tcctctacag ccttctcttc ttcaggagct tctggttgct tttctggctc aactggtgcc
    60181 gttggtgcct gttcgtcttc acttggctcg actggttcac ctacttgttc aacttttggt
    60241 tcctctgttg gtttgtctga tggttgactt tctggcttaa ctgctacttt ttcctctggt
    60301 tttgactcaa cttctccacc tacttcttca actggagctg gttctgctga atcttctttc
    60361 ccctcttcta ctttaggaag ggtgtcgtca gtaggtttta tctccgattt tggttcttcc
    60421 tttggacttt cttctgtttt aggtgcttct tcttttggag cttcctctgt ctctactact
    60481 tggttttctg tcctagcttg ctcctgattt gttgttgatt gaggagtctc aacttcgact
    60541 acagtcacct ctccaggttg tgctgaggtt tcttctaaaa cagtgtccaa gccaagcgtt
    60601 ttgaggatgt cacctgatag ataaccaaca tagcgatagc catccatttc aacaacaccc
    60661 tctcgactag ccagcgctag ggtcacaact gggtctacag cctctgcact aggaagaact
    60721 accaatccca tagctccaac tagaaagacg ctagcaattt tctttctctt gtagattaaa
    60781 agcaagctcc caacagtcag caaaccaaaa gctgtcaaaa cagatgcttc tgtccctgtt
    60841 tgaggcaact gatctttttg atacaccaaa ccatatacaa cttcattcct gtcaggcttt
    60901 cctgtctgaa ttaaatcttt agcttcttgt gaaataatct ctttatttac atagtgatag
    60961 gtggctgcgt ccactacaga aggagccatc aaaaggcttc caagaaatac agagcctaca
    61021 actcccttaa tcttacgaat tgaaaaacgg tcttttttaa acacttttat ctcctttatt
    61081 cattctcaag actttctaat agcgtcttgc ggatagtgcg cacgcgcacc tccgattaat
    61141 tttggacgat tagccagtgc cgttacatgg gcatgaccaa tctctctcaa aatagggcga
    61201 atcggaacct gaacatgctt gacatgcatg ccaattgcag tgtctccgat atccaatcca
    61261 gcatgagcct tgataaattc aacctcaact ggatcctgca taaacttaaa ggctgccaac
    61321 tgccccgaac ctcctgcatg aagagtagga tggacactga caatttccag atcaaactgc
    61381 tctgccacct gacgttcaac aacgagagcc cgattgacat gctcacaacc ttgaactgct
    61441 aaatggatac ctctactacc tagaataccc aagatagtct ccactatcag ctcaccaatc
    61501 tcttgactgg attctttccc aatctgacca cctagcacct cactagaaga tagacctaaa
    61561 acaaaaaggg ccccctgctt caaattggtc ttttctaaaa catcttccac tacctgacgt
    61621 gtttctcttt gaatctgtgt ctcgttcatc tctgttacct ctgttgtcac tcttctatca
    61681 taccgttttt tcttgttttt agcaagatag acaacctaga aagtttgccc aattacgcat
    61741 aaaactccca gaattgactg ggagttagct agtttctatt ctatttatat atatttcaac
    61801 tttcgtccct ttttggggtc tagaatcaat cttcatctgg taattggctc caaaatgaag
    61861 tttgagccgt tgatcgacat tttgaagacc aactccccca cgtttgagtt gactttgact
    61921 actatcacca gcatcttgga agccaacgcc atcatcctca atacggatga ccaatcccga
    61981 atcctgtttc tggacagaaa gtttaatatg gccctgacct tccttttcct taatgccatg
    62041 gtaaagagca ttttctacaa ggggttgtag gaccagcttg ggtaagacta aattatcaaa
    62101 ggcaacattt tcattaattt cgtattccag cttatctcca tagcgttgtt tctggataaa
    62161 gagatactgg cggacatgat tgatttcgtc agagagacaa atcaagtcct tgccttgatt
    62221 gagcgccaag cggaaatagg ttgccaagga cttggtcacc tgcaccactc gctgactatc
    62281 atgaaattca gccatccaga tgatggtgtc caaagtgtta tagaggaaat gtggattaat
    62341 ctggctcgaa agggcttgaa gttggtactg acgggtcgtt tcttcctggc tacgaatagc
    62401 taccatcaac tgatcaatct gatccaacat ggcattaaat tggcgagtta cttctctcag
    62461 ttcataggca ccaacttcct tggcacgaag attttgagca ccagaagcaa tttccaacat
    62521 ggtttctctc aaatccttca aaggagcaat ccagcgttta agactgaacc acactaagca
    62581 gagacagaca agaagagatg tgacactggc cccaagcaag gtccacaaga gctgactccg
    62641 aacctggtct aacttttcca atgatgacac gccaagtacc gtccaatcag ttcctgcaat
    62701 cttctcttga ctgacgtagg atttgtgacc aggagtataa ccctgacctg tctcgatgta
    62761 gggtttcata gcctccattt tgctagacga actataaact gtgtgttgag gatggtagac
    62821 aaattcatgg ttttcattga taatgaaggc aaagccctgc tgccccaact ggagttgatt
    62881 gagataggct tccagagttt cataagaaat atccaaacga agcacaccaa gattggctcc
    62941 ctttgcatca acaagttctt gagtgacaga aatgacccac tgactatctg atttacgagc
    63001 tggagtcaaa acaggcatag ctccctgatg aatagccttt tggtaccaat cctcagccat
    63061 catatcagag gaagttttca tctgcacact gtcatctgta gaaatgacct gaccagattt
    63121 ggtcaccagc acaacagttt tcaagtcctt atctgacttc aagatggtca aaaacaaatc
    63181 tcggattccc tcgaccttgt cttgactggg attctcagca taggccagaa catccgtctg
    63241 ctgggtcaaa ccagtcgagg tggtttctag ttttttgata taagactgaa taaagtggct
    63301 agtctggctg atggtcgttt ggctgttgcc ctcaatggtg gcctcaatgg ctgaagaact
    63361 tgattgatag tagaaagttc caaccagagc taggagaatg agaaagacca gaaagatgga
    63421 aataaccatt ctaactaaaa gagaagaacg cttcatcggt cttctccctt cttaaactga
    63481 cgaggtgtca cacctgcaat ctgcttaaaa cgttgggtaa aatagttcat atcttcaaaa
    63541 ccaaccttct ctgcgatctc ataaatcttc agatctgtag ttaaaagcaa gagcttggct
    63601 tgtttaacac gttctctcac cagataatcc tgaaaaggca agcccaactc tttcttaatc
    63661 aaggaactca gataggtcgg actaaaacct aagtcactgg ctaaagactt taaactaaat
    63721 tggctatcag ccagatgaga ctggattttc tgggccatgt ttccttcaaa cctattagtc
    63781 aataaatctt gtaactgctc ttctttctct tccttgtcta gtttttgttt gattttcccc
    63841 aacatttcct caatatcctg acgagaaaag ggtttgagca ggtagtcgtc cacacctagt
    63901 ttgacagcag acaaggcata atcaaaatca tcgtaacctg ttaaaaagac caaatgaacc
    63961 tgaggatagg tttctcgtac cagactggcc aactggatgc catttagatg aggcatgttg
    64021 atatcggtta aaatgatatc tggcacctgc ttttggatca actcccaagc ctgccttcca
    64081 ttttcagcct gaccgatgat ttccatatcg taggctgcta cattgaccag tttagtcaaa
    64141 ccttgtctta ccagatattc atcttctacg attaagattg tgtaggtcat gctctgctcc
    64201 tttaccactt actagtatca gtatagcaaa attctcctct aactgcttag gaaagacctc
    64261 ttatactcaa taaaaatcaa aaagtaaact aggaagatag ccacaggttt ctcaaagtat
    64321 agctttgagg ttgta
//
LOCUS       DBERPV010000009        57424 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.09, whole genome shotgun sequence.
ACCESSION   DBERPV010000009 DBERPV010000000
VERSION     DBERPV010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 57424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57424
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.09"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..646)
                     /locus_tag="ACL8C7_000760"
     CDS             complement(<1..646)
                     /locus_tag="ACL8C7_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1395008.1"
                     /translation="MIKLEFLKQKKSILWFVLIFPIILNALLYIDLTFRYRGYLLVHQ
                     NELALSNWQLIFKEQTIFYFSELFYLVLSLIIYEVFAVEFKNDAWLTVISLPFRNKYT
                     INSKLLITVVYTFTFWLSDYISLYVIGKAIDNSLEIGLIFFLKTFTIQLISSLMIMLL
                     YFLTLVLIRKISGIIPIGIIMMILTISIYYNDYNFKIYLPFTYLSHAFRVTESQF"
     gene            complement(639..1367)
                     /locus_tag="ACL8C7_000761"
     CDS             complement(639..1367)
                     /locus_tag="ACL8C7_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1395009.1"
                     /translation="MAIVEIINLTKSFKDIEVIHNTSFYLNKGKVYGFVGPNGAGKTT
                     IIKMILGILKPDSGKITIFNQTVEQNSENILSRIGLVLGPSFYGHLDAYKNLKLIANM
                     KGLSLDTERLNEYLSMVGLKDVKKKKVKNFSMGMKQRLSIAASLLGSPEILIWDEPIN
                     GLDPQGVIEIRSLIRFLQEKKGITFLISSHILSELDKVISDIIIINYGKVEFFGSCHY
                     LLQKYNCRNLEEAYLACLAGGEYD"
     gene            complement(1401..1571)
                     /locus_tag="ACL8C7_000762"
     CDS             complement(1401..1571)
                     /locus_tag="ACL8C7_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395010.1"
                     /translation="MKKVNEYVISTAASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIFYKNNKN"
     gene            complement(1584..3395)
                     /locus_tag="ACL8C7_000763"
     CDS             complement(1584..3395)
                     /locus_tag="ACL8C7_000763"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HGS1395011.1"
                     /translation="MDPSKGYINYEFKEFSKHFSNIVLLSFPNENYQSLKSQFPSPWI
                     RVFSSFSKVKGRLILTLLFSIISYLIILSVPVMTSKFINSALGNTFSFQTSFLILFSL
                     LCLYLISILARSMGILFSNIFFSRDIESFTFKHLLKLPYSFFELRAKGDILYRISSLS
                     GFRELFTNQVVGGVVDIGTILSVVIYMFLSSKTLSIIALILSLINFLFLFSTRKIMYD
                     TVNRELQEQSLIYSVETEALNTISSIKISGLEDEIYENWSKYLKNVLTKYKKRSIVHI
                     LYNSATNVFQLFAPIIILIFGLDNVLNGKILLGEVVAFQTMASILFSSEISIFNAYTQ
                     YILAAGYLNRVNDIWLENEENVENGLKKCSLEGRIDIKDLSFSYSKDSAPVIENLNLT
                     IEPGQRIALVGQSGSGKSTLSKILSGLYKIDTGKVLFDGVNINQIDKKILSQNLGVVP
                     QDSFLLNRSILDNITLKNEVTSQKIEEVCKAVQIYDEIMAMPMKFNTIISEMGSNISG
                     GQRQRIALARALINNPSIVILDEATSALDTINEERITKYIQSQGCTQIIIAHRLSTIK
                     DADIIFVMKGGKIVESGNHKYLMDLGGEYYSLYTKRK"
     gene            complement(3395..3757)
                     /locus_tag="ACL8C7_000764"
     CDS             complement(3395..3757)
                     /locus_tag="ACL8C7_000764"
                     /inference="COORDINATES: protein motif:HMM:NF015377.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine peptidase family C39 domain-containing
                     protein"
                     /protein_id="HGS1395012.1"
                     /translation="MFITGVKEDMMTRKVPNIEQMSQIECGLCCCLSILHFYKSKETL
                     LDLRRDIEKGRDGYSIGDLKQLLNKRNFDTDSYQVKDVNKISELPLPLIAFWDNQHYV
                     VIYKVKKNKVYIKRIRSI"
     gene            complement(3738..4268)
                     /locus_tag="ACL8C7_000765"
     CDS             complement(3738..4268)
                     /locus_tag="ACL8C7_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000059557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="HGS1395013.1"
                     /translation="MSLSYYYEINPSTDILKCIEELLYKEDKCFNNILKNWKDIRRNH
                     NDSFPNFWCYGAPGILLARKEIFDKTNIGNNDLSIIENVLTNVEKIRELNLCHDSVGT
                     ISCLDAILKDEENLLIKESIDFYFDNVVSQVIKPELSTDLNTMNTFSFMLGVSGVVYE
                     ISRKQDDRLLNVYYWS"
     gene            complement(4349..4411)
                     /locus_tag="ACL8C7_000766"
     CDS             complement(4349..4411)
                     /locus_tag="ACL8C7_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HGS1395014.1"
                     /translation="MKKISKFLPILVLVMDIIII"
     gene            4491..5345
                     /locus_tag="ACL8C7_000767"
     CDS             4491..5345
                     /locus_tag="ACL8C7_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HGS1395015.1"
                     /translation="MKSKLGITLRKVRKGKQISLCSVADEHLSKSQISRFERGESEIS
                     CIRLINILDKLHITLDEFLVLYNDDYTSSESFANLVQYIRKQYSSQSINNIACLLSDT
                     SDYTLNSFEKTMVKSILHTMDSNIIPSDEELLHLTDYLFKVEKWGYYEIILLGNCVRT
                     INYNSYFLLTKEMLNNYIYSSLNKTNKQIVSQLAINCFILSIDKEEFSNCSYLISKIK
                     TLLDNELNFYEQTVFLYATGYFEFKRCQSTSGIEKMKQAIQVFDILGEDKLKLHYTDH
                     FNKLVNKK"
     gene            complement(5390..7255)
                     /locus_tag="ACL8C7_000768"
                     /pseudo
     CDS             complement(5390..7255)
                     /locus_tag="ACL8C7_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261806.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1250 family conjugative relaxase"
     gene            complement(7242..7607)
                     /gene="mobC"
                     /locus_tag="ACL8C7_000769"
     CDS             complement(7242..7607)
                     /gene="mobC"
                     /locus_tag="ACL8C7_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HGS1395016.1"
                     /translation="MVYRYRTNLKKVFLTDSELHQLNERIAKSNCQNFSVYARKVLLN
                     PNMSFVTINTDTYDQLVFELRRIGNNINQIARAINQSHLISQDQLQELSKGVGELIKE
                     VDKEFQVEVKRLKEFHGSY"
     gene            complement(7617..7976)
                     /locus_tag="ACL8C7_000770"
     CDS             complement(7617..7976)
                     /locus_tag="ACL8C7_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1252 family conjugative relaxosome accessory
                     protein"
                     /protein_id="HGS1395017.1"
                     /translation="MSEQYRDIRKEVNLTADELKQIEKMMEVDNYRHFSPFVRDKILM
                     IDDKQLAAKEWFSLWQSQKFEQISRDVHLVLIIARENHQVTQEHVSILLTCVQELIAE
                     VNQVQSLSRGFREKYMR"
     gene            complement(8781..11279)
                     /locus_tag="ACL8C7_000771"
     CDS             complement(8781..11279)
                     /locus_tag="ACL8C7_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001213956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spaf_1101 family AAA-like ATPase"
                     /protein_id="HGS1395018.1"
                     /translation="MRGFNNKIKSVYQELTNSKEKFGSFHKTLIHLHTPVSYDYKLFS
                     NWTATKYRKITEDELYDIFFENKKIKVDKTIFFSNFDKVVFSSSKEYISFLMLAEAII
                     KNGIEIVVVTDHNTTKGIKKLQMAVSIIMKNYPIYDIHPHILHGVEISAADKLHIVCI
                     YDYEQESWVNQWLSENIISEKDGSYQHSLTIMKDFNNQKIVNYIAHFNSYDILKKGSH
                     LSGAYKRKIFSKENTRFIGVKNINSIEGSRKKLLADFNCEPNFLLDNDSHEIDSLGKN
                     NLWLKGGKISFKMFQEALFDYNVSVSLCKPSFKQKSYIKGLYIENRGENRSFLAGDKL
                     KKDKDFFLTFSPSMNCLIGGRGTGKSTLIDMLQFVLSQDCDKQSKLEFLCNHANAFVL
                     YVLEETEYIIEVSLPDVKQENKDNILQYYGQNRENKFGYPYRFNSDTIKEWTRSQYTT
                     VYKVEGNHFKLVDKTRILEKMFDRRYSVNELVKTADGEKITEFISNLMIKNKKLPRPD
                     YGLRTQTLKSFEVKLKELDEYLKQRKQLILKIIEDFNETQIGKLRICYEQIDRWEEPH
                     FENYLFKNNRSSFDNYRISMQDVADVLYLIYRELGMKEFVKVIVRQNIPNKYFMLLKS
                     ISEDNFAKQENNWRDKSEINEYNITHLKKSIYSLIENSSLLNEFKRVLKEHVANERLF
                     LEFNINSKESSQQLDILYKEVGVLSLGQKVVAMLDFLLAYSDYSKDFRPLIIDQPEDN
                     LDNRYIYRHLVQQFRDVKAQRQIILATHNATIVTNSMTDQVVIMESDGVNGWIESQGY
                     VSEKYIKNHIINQLEGGKDSFKHKMSIYETALSE"
     gene            complement(11307..12068)
                     /gene="pezT"
                     /locus_tag="ACL8C7_000772"
     CDS             complement(11307..12068)
                     /gene="pezT"
                     /locus_tag="ACL8C7_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin PezT"
                     /protein_id="HGS1395019.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TELSHLGYNLLIEGTLRTIDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAADVLHELLFGEWSQVEKEMLQVGEKRLNELLEK"
     gene            complement(12068..12544)
                     /gene="pezA"
                     /locus_tag="ACL8C7_000773"
     CDS             complement(12068..12544)
                     /gene="pezA"
                     /locus_tag="ACL8C7_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin PezA"
                     /protein_id="HGS1395020.1"
                     /translation="MIGKNIKFLRKTYDLTQPEFARIVGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIQTNIYLVENFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            complement(12989..13444)
                     /locus_tag="ACL8C7_000774"
     CDS             complement(12989..13444)
                     /locus_tag="ACL8C7_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395021.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNAIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
     gene            complement(13719..15458)
                     /locus_tag="ACL8C7_000775"
                     /pseudo
     CDS             complement(13719..15458)
                     /locus_tag="ACL8C7_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
     gene            complement(15621..16505)
                     /locus_tag="ACL8C7_000776"
     CDS             complement(15621..16505)
                     /locus_tag="ACL8C7_000776"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGS1395022.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKTRNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            complement(16617..17471)
                     /locus_tag="ACL8C7_000777"
     CDS             complement(16617..17471)
                     /locus_tag="ACL8C7_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HGS1395023.1"
                     /translation="MLGAIIGDIVDSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(17529..18287)
                     /locus_tag="ACL8C7_000778"
     CDS             complement(17529..18287)
                     /locus_tag="ACL8C7_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HGS1395024.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGACLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            complement(18349..18537)
                     /locus_tag="ACL8C7_000779"
     CDS             complement(18349..18537)
                     /locus_tag="ACL8C7_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HGS1395025.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(18858..19424)
                     /locus_tag="ACL8C7_000780"
     CDS             complement(18858..19424)
                     /locus_tag="ACL8C7_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395026.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(19692..21372)
                     /locus_tag="ACL8C7_000781"
                     /pseudo
     CDS             complement(19692..21372)
                     /locus_tag="ACL8C7_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(21464..21625)
                     /locus_tag="ACL8C7_000782"
     CDS             complement(21464..21625)
                     /locus_tag="ACL8C7_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395027.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            complement(22309..23037)
                     /locus_tag="ACL8C7_000783"
     CDS             complement(22309..23037)
                     /locus_tag="ACL8C7_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HGS1395028.1"
                     /translation="MATNKRYYWIKLKEEFFTDKRIKRLRRISGGDTYTIIYLKLLLL
                     SLKDEGKLYYDGVESDFIKELALTIDETDDDVMVTVNYLINQGLLEVVTENDEYYLTE
                     IPNLIGSETAWAEKNRRYRQNKQRTLSLMSPTHVRQEIEIEKDIEIDKEREGEIDKKS
                     TPIFYGEFKNVRLSKEEYKNLKEKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWY
                     EEDKDKLRQKGLNKKMNYDVGESL"
     gene            complement(23164..23691)
                     /locus_tag="ACL8C7_000784"
     CDS             complement(23164..23691)
                     /locus_tag="ACL8C7_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HGS1395029.1"
                     /translation="MINEEISKEAGQAAQTIISYTIKATKESINLEKEIRKKMNETLE
                     KANGNLKSLMGDEMKIKDLYKKGQLENISIDQIDLKDLKKELNKLGVSFSVMKNKESK
                     NYEIFFQAKDIKVMEYAFKQVIAKENKKEKESILKQIKKYKDLSKNKDKTKEKGKRKV
                     KEKVKPNKKDMTREI"
     gene            complement(23877..24050)
                     /locus_tag="ACL8C7_000785"
     CDS             complement(23877..24050)
                     /locus_tag="ACL8C7_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019118552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395030.1"
                     /translation="MNKRQELIDELIKANEDGTYKTYKSTEEIKAMNNEEIQIIYSNM
                     KNYLSDKRTHINY"
     gene            complement(24124..25763)
                     /gene="mobQ"
                     /locus_tag="ACL8C7_000786"
                     /pseudo
     CDS             complement(24124..25763)
                     /gene="mobQ"
                     /locus_tag="ACL8C7_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019213953.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MobQ family relaxase"
     gene            complement(26077..26409)
                     /locus_tag="ACL8C7_000787"
     CDS             complement(26077..26409)
                     /locus_tag="ACL8C7_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000968321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HGS1395031.1"
                     /translation="MMASKRLSIEEQIEKKEESIKQLQNQKRQLKKKLNEQERKARNK
                     RLIEKGAVFESIFEESIFEESIDLTKDEFYKLIKTLNDEEIRLNIMEILEERIDDNVE
                     KSSKDEIT"
     gene            complement(26465..26944)
                     /locus_tag="ACL8C7_000788"
     CDS             complement(26465..26944)
                     /locus_tag="ACL8C7_000788"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: protein motif:HMM:NF013579.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS1395032.1"
                     /translation="MFITEKKRKSSQVPTGSSIPKRYLLDGKTPRISATNIDNGILGY
                     YEDIDDKNYRVFENFISVSFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSI
                     IRQALKNTEYKDQISSTVLPDIKIKLPIDSRGTPDWNYMERYIEDLKLKCNIANYNI"
     gene            complement(26943..27127)
                     /locus_tag="ACL8C7_000789"
                     /pseudo
     CDS             complement(26943..27127)
                     /locus_tag="ACL8C7_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612340.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(27278..28072)
                     /locus_tag="ACL8C7_000790"
     CDS             complement(27278..28072)
                     /locus_tag="ACL8C7_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1395033.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVENLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
     gene            complement(28072..29079)
                     /locus_tag="ACL8C7_000791"
     CDS             complement(28072..29079)
                     /locus_tag="ACL8C7_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HGS1395034.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(29079..30086)
                     /locus_tag="ACL8C7_000792"
     CDS             complement(29079..30086)
                     /locus_tag="ACL8C7_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HGS1395035.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(30076..31101)
                     /locus_tag="ACL8C7_000793"
     CDS             complement(30076..31101)
                     /locus_tag="ACL8C7_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HGS1395036.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNILG
                     NACKNAK"
     gene            complement(31222..31491)
                     /locus_tag="ACL8C7_000794"
     CDS             complement(31222..31491)
                     /locus_tag="ACL8C7_000794"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395037.1"
                     /translation="MTLRTEDQVRDYAREVLGFNEVEENINQGTGQITTFNQLGFKGY
                     SDKPDGWYLPKNMNDVAIILETKSEERDISKQIFIDELMKNIDII"
     gene            complement(31495..31713)
                     /locus_tag="ACL8C7_000795"
     CDS             complement(31495..31713)
                     /locus_tag="ACL8C7_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS1395038.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(32004..32237)
                     /locus_tag="ACL8C7_000796"
     CDS             complement(32004..32237)
                     /locus_tag="ACL8C7_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit M"
                     /protein_id="HGS1395039.1"
                     /translation="MKKDKEVYDNVCEYLSPHLNKDMEVLELACWFRVIIVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYSIHFNNGYCN"
     gene            complement(32451..34081)
                     /gene="rlmD"
                     /locus_tag="ACL8C7_000797"
                     /pseudo
     CDS             complement(32451..34081)
                     /gene="rlmD"
                     /locus_tag="ACL8C7_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
     gene            complement(34155..35129)
                     /locus_tag="ACL8C7_000798"
     CDS             complement(34155..35129)
                     /locus_tag="ACL8C7_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HGS1395040.1"
                     /translation="MRKKLFLTSAAILWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKGFGS"
     gene            complement(35203..35817)
                     /gene="pmp23"
                     /locus_tag="ACL8C7_000799"
     CDS             complement(35203..35817)
                     /gene="pmp23"
                     /locus_tag="ACL8C7_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HGS1395041.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNRTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(35817..36791)
                     /locus_tag="ACL8C7_000800"
     CDS             complement(35817..36791)
                     /locus_tag="ACL8C7_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HGS1395042.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(36799..38055)
                     /gene="glyA"
                     /locus_tag="ACL8C7_000801"
     CDS             complement(36799..38055)
                     /gene="glyA"
                     /locus_tag="ACL8C7_000801"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HGS1395043.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYED"
     gene            complement(38117..38548)
                     /locus_tag="ACL8C7_000802"
     CDS             complement(38117..38548)
                     /locus_tag="ACL8C7_000802"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1395044.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEEEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIC"
     gene            complement(38550..39149)
                     /locus_tag="ACL8C7_000803"
     CDS             complement(38550..39149)
                     /locus_tag="ACL8C7_000803"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HGS1395045.1"
                     /translation="MDRIRQELENGGAVILPTETVYGLFSKALDEKAVDHVYQLKRRP
                     RDKALNLNIASFEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLAT
                     IGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFLT
                     GQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(39136..39975)
                     /gene="prmC"
                     /locus_tag="ACL8C7_000804"
     CDS             complement(39136..39975)
                     /gene="prmC"
                     /locus_tag="ACL8C7_000804"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HGS1395046.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPAWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDATDYLKDSGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQDRMVVVDD
                     GQD"
     gene            complement(39975..41054)
                     /gene="prfA"
                     /locus_tag="ACL8C7_000805"
     CDS             complement(39975..41054)
                     /gene="prfA"
                     /locus_tag="ACL8C7_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HGS1395047.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(41064..41543)
                     /locus_tag="ACL8C7_000806"
     CDS             complement(41064..41543)
                     /locus_tag="ACL8C7_000806"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1395048.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKEYQKQFIATNAISLAEAYVYTK
                     NGDFVAPLAVYDNDVIIGFVMIAYDKKIGISSGNYLLFRFMIDKNFQNQGYFKPIMDK
                     VLDYVRTAPAGLSNKLWLSYEPENEQARFCYLSYGFKETGEISENEVVAIYDLTIEK"
     gene            complement(41533..42132)
                     /locus_tag="ACL8C7_000807"
     CDS             complement(41533..42132)
                     /locus_tag="ACL8C7_000807"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HGS1395049.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPMITSNKEQNYDN"
     gene            42255..42437
                     /locus_tag="ACL8C7_000808"
     CDS             42255..42437
                     /locus_tag="ACL8C7_000808"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HGS1395050.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            42574..43947
                     /gene="mnmE"
                     /locus_tag="ACL8C7_000809"
     CDS             42574..43947
                     /gene="mnmE"
                     /locus_tag="ACL8C7_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HGS1395051.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQETNRII
                     LLNKTDLPETIETSELPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(43994..44929)
                     /gene="dapA"
                     /locus_tag="ACL8C7_000810"
     CDS             complement(43994..44929)
                     /gene="dapA"
                     /locus_tag="ACL8C7_000810"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HGS1395052.1"
                     /translation="MSYQDLKKCKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAVLNYMGFEAGPTRLPL
                     IPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(44985..46061)
                     /locus_tag="ACL8C7_000811"
     CDS             complement(44985..46061)
                     /locus_tag="ACL8C7_000811"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HGS1395053.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(46403..46475)
                     /locus_tag="ACL8C7_000812"
     tRNA            complement(46403..46475)
                     /locus_tag="ACL8C7_000812"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(46440..46442),aa:Thr,seq:ggt)
     gene            complement(46575..47084)
                     /locus_tag="ACL8C7_000813"
     CDS             complement(46575..47084)
                     /locus_tag="ACL8C7_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HGS1395054.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(47082..47178)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            47207..47638
                     /locus_tag="ACL8C7_000814"
     CDS             47207..47638
                     /locus_tag="ACL8C7_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HGS1395055.1"
                     /translation="MKIPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            47720..48097
                     /gene="mscL"
                     /locus_tag="ACL8C7_000815"
     CDS             47720..48097
                     /gene="mscL"
                     /locus_tag="ACL8C7_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HGS1395056.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKEE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(48139..49233)
                     /gene="hemH"
                     /locus_tag="ACL8C7_000816"
     CDS             complement(48139..49233)
                     /gene="hemH"
                     /locus_tag="ACL8C7_000816"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004325 - ferrochelatase activity
                     [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HGS1395057.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSKQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            49388..50608
                     /gene="pepT"
                     /locus_tag="ACL8C7_000817"
     CDS             49388..50608
                     /gene="pepT"
                     /locus_tag="ACL8C7_000817"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HGS1395058.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTSLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSNRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVRSL"
     gene            complement(50651..51304)
                     /locus_tag="ACL8C7_000818"
                     /pseudo
     CDS             complement(50651..51304)
                     /locus_tag="ACL8C7_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672614.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family hydrolase"
     gene            51302..51466
                     /locus_tag="ACL8C7_000819"
                     /pseudo
     CDS             51302..51466
                     /locus_tag="ACL8C7_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057566.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(51756..52854)
                     /locus_tag="ACL8C7_000820"
                     /pseudo
     CDS             complement(51756..52854)
                     /locus_tag="ACL8C7_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(53080..56199)
                     /gene="phtE"
                     /locus_tag="ACL8C7_000821"
     CDS             complement(53080..56199)
                     /gene="phtE"
                     /locus_tag="ACL8C7_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HGS1395059.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGISHEKHEEDGYGFDANRII
                     AEDESGFIMSHGNHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPGN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
     gene            complement(56409..>57424)
                     /gene="phtD"
                     /locus_tag="ACL8C7_000822"
     CDS             complement(56409..>57424)
                     /gene="phtD"
                     /locus_tag="ACL8C7_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HGS1395060.1"
                     /translation="QITYTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHM
                     THSHWIKKDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKK
                     VPLDRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVK
                     YYVEHPNERPHSDNGFGNASDHVQRNKNGQADTNQTEKPNEEKPQTEKPEEDKEHDEV
                     SEPTHPESDEKENHAGLNPSADNLYKPSTDTEETEEEAEDTTDEAEIPQVEHSVINAK
                     IAEAEALLEKVTDSSIRQNAVETLTGLKSSLLLGTKDNNTISAEVDSLLALLKESQPT
                     PIQ"
BASE COUNT        16904 a        11185 c         8880 g        20455 t
ORIGIN      
        1 aaaattgact ttcagtcact ctaaaagcat gagaaagata agtaaatggt aagtaaatct
       61 taaaattata atcgttgtag tatatgctaa ttgttaaaat catcattata ataccaattg
      121 gtattattcc agaaattttc cttataagta ctaaagttag aaaatataat aacattatca
      181 tcaacgagga aattaattga atggtaaatg tttttaaaaa gaaaatcaaa ccaatctcta
      241 aactgttatc aatagccttc ccaataacgt ataagctaat ataatcagac aaccaaaaag
      301 taaatgtgta aaccactgta atgagtaatt tagaatttat tgtgtacttg tttctaaatg
      361 gcaatgaaat tacggttaac catgcatcat ttttaaattc tactgcaaac acttcgtaaa
      421 ttattaaaga tagaactaaa taaaatagtt cagaaaaata aaatattgtt tgttctttaa
      481 aaattaactg ccaattagat aaagcaagtt cattttgatg caccaataaa taacctcgat
      541 acctaaaagt taagtctata tataacaaag cattcagaat tattggaaaa ataagaacaa
      601 accataagat gctttttttc tgctttagaa actctaattt aatcatattc acctccagct
      661 aaacaagcta agtaggcttc ttccagattt cgacaattat acttttgtaa aaggtagtgg
      721 caagaaccaa aaaattcaac tttcccataa tttataatta taatatcaga tatcacttta
      781 tccagttcac taagaatatg acttgatatt aaaaatgtaa tacctttttt ctcctgtaga
      841 aaacggatta aacttctaat ttcaattaca ccctgtggat caagtccatt gattggttca
      901 tcccaaatta atatttctgg actacctaac aatgatgcag ctatacttag acgttgtttc
      961 atgcccattg aaaaattttt cacttttttc tttttaacat cttttaatcc taccattgat
     1021 agatattcat taagtctttc agtatctaaa ctaagccctt tcatatttgc tattaacttc
     1081 aaatttttat aagcatcaag atgaccataa aatgaaggtc ccaaaactaa tcctatccta
     1141 gataatatat tttcggaatt ctgttctacg gtttgattaa aaatagttat tttcccagaa
     1201 tctggtttta aaatccctag aatcattttg ataattgtag tttttccagc cccatttggt
     1261 ccaacaaaac catatacttt tcccttattt aaataaaatg aagtgttatg aataacttca
     1321 atatctttaa agctttttgt tagatttata atttcaacta tagccatctc tactccttag
     1381 tttacagcaa aaaattatgc ttaattctta ttgtttttgt aaaaaatcag cgaacctaat
     1441 actattccat tcaacaaacc taaagaaata ccatattcaa ctggaaaatc taaaaaaatt
     1501 gcaaatacta ttccaatcat cacccctagt gaggctgctg ttgaaattac atattcattt
     1561 actttcttca ttttctttac acctcatttc ctttttgtat ataagctgta gtactctcca
     1621 ccaagatcca ttaagtactt atgatttcct gactcaacaa tcttaccacc tttcattaca
     1681 aaaataatat ccgcatcctt aatcgttgac aatctatgag ctataattat ttgagtacaa
     1741 ccctgacttt gtatatactt tgttattctt tcctcattaa tagtgtctaa tgcactagtt
     1801 gcttcatcta aaattacaat actaggatta tttattaatg cacgtgccag tgctatccgt
     1861 tgcctttgcc cacctgaaat atttgacccc atctctgaga tgatagtatt aaatttcatc
     1921 ggcatagcca tgatttcatc atagatttga actgctttac aaacttcctc tatcttttgt
     1981 gaagtaactt cgttctttaa agttatatta tcaagaatac ttcggttcaa taaaaatgaa
     2041 tcctgtggaa ctactcctaa attttgactt aatatttttt tatctatttg attaatattt
     2101 acaccatcaa ataaaacttt tcctgtatca atcttatata atcctgatag tatttttgat
     2161 aacgtacttt ttcctgaccc cgattgaccg actagtgcaa ttctctgtcc tggctcaata
     2221 gtcaaattta aattttctat tacaggagct gagtctttgg aataagagaa agataggtcc
     2281 ttaatatcta ttctaccttc taaagaacac tttttaagac cattttcaac attctcttca
     2341 ttttcaagcc agatatcatt tactctattt aagtatcctg ctgccaaaat atactgcgta
     2401 taagcattaa atattgagat ttctgaacta aataaaattg atgccatggt ttgaaatgcg
     2461 acaacctcac ccaataaaat ttttccattt aaaacattat caagtccaaa aatcaatata
     2521 attataggag cgaacaattg aaatacatta gtagctgaat tgtataaaat atgcacaata
     2581 cttcgttttt tatactttgt caatacgttt tttaaatact tagaccagtt ttcatatatt
     2641 tcatcttcta atcccgatat ttttattgaa gaaatagtat ttaatgcttc tgtttctact
     2701 gagtaaatca atgattgttc ttgtaattct ctattaaccg tatcatacat tatttttcta
     2761 gtactaaaca gaaacaaaaa attaattaaa ctcaatataa gagctataat tgataatgtt
     2821 tttgaactaa gaaacatata tattacaaca cttagaatag tcccgatatc tactactccc
     2881 ccaacaactt ggttagtaaa tagctcccta aaaccactaa gactagaaat tctgtataaa
     2941 atatctcctt ttgccctgag ttcaaaaaaa ctatatggta gtttaagcaa atgcttaaat
     3001 gtaaaacttt caatatctct actaaaaaat atattagaaa atagaattcc catactccta
     3061 gccaagatag aaataaggta caaacaaagt agagaaaata aaattaaaaa cgaggtttga
     3121 aaagaaaatg tattccctaa tgcagaatta ataaactttg aagtcattac tggtacggaa
     3181 agtattatta agtaacttat tattgaaaat agtaacgtca aaatcaatcg accttttacc
     3241 tttgaaaaac tagagaatac tcttatccat ggagaaggaa actgcgactt caaagattga
     3301 taattttcgt taggaaatga tagcagtact atattactaa aatgttttga aaactcctta
     3361 aactcataat ttatatatcc tttagaagga tccattatat agaccttatt ctttttatat
     3421 agaccttatt cttttttact ttgtaaataa ctacataatg ttgattatcc cagaatgcta
     3481 ttaatggtaa cggaagttca ctaattttat ttacatcttt aacttgatat gagtcagtat
     3541 caaaatttcg tttattcaat aactgtttca agtcacctat actataacca tctctccctt
     3601 tttctatatc acgtcttaaa tctagtaatg tctctttgct tttatagaaa tgtagtatgg
     3661 acaagcagca acataaacca cattctattt gagacatttg ctcaatatta ggtacttttc
     3721 tagtcatcat gtcctcttta actccagtaa taaacattaa gtaatctatc atcttgtttt
     3781 cgagatattt catagacaac tccagatact cctagcataa aagaaaatgt attcatagta
     3841 ttcaaatccg tacttaattc tggtttgata acctgagaaa cgacattatc aaaataaaaa
     3901 tctatagatt cttttattaa taggttttct tcatctttca atattgcatc aagacaactg
     3961 atagtaccta cagaatcgtg acataaattc aattctctta ttttttctac attagttaat
     4021 acattttcaa ttattgataa atcattattc ccaatattag ttttatcgaa aatttctttt
     4081 ctagctaata aaatgcccgg agctccataa caccaaaaat taggaaagga atcattatga
     4141 tttcttctta tgtctttcca attttttaat atattattga aacatttatc ttctttatat
     4201 agtaattcct ctatacattt taatatatct gtactaggat taatttcata ataatatgat
     4261 aatgacattg ctactccaga ataaccgtgt gttaaacctg ttactgttat attatctaat
     4321 tgtgaaatac aataattaat acactttttt aaatgatgat aatatccatc accaaaacca
     4381 aaatcggtaa aaattttgaa attttcttca tacttggact tcctttccgt ttttatttat
     4441 tgtacaataa ataaaaacgg atttaatttt tgttgggaaa atgggaaatt atgaaatcaa
     4501 aacttggcat cacacttaga aaagttcgta aaggaaaaca aattagtcta tgctctgtag
     4561 cagatgaaca tctttcaaaa tcacaaatat ctcgttttga acgtggggag tcagagatat
     4621 cttgtattcg actaatcaat attttagaca aattacatat tactttggat gagttccttg
     4681 ttttatacaa tgacgactat accagttccg aatcatttgc taatctagta cagtacattc
     4741 gtaagcaata ttcatcacaa agtatcaata atatagcatg tctactttct gatacttctg
     4801 attacactct aaattctttt gagaaaacaa tggtaaaatc tattttacac acaatggatt
     4861 cgaacatcat tccatcagat gaagagcttc ttcatctgac agactatctt ttcaaagttg
     4921 aaaaatgggg ctattatgaa atcattttat taggtaactg tgtacgcaca attaactaca
     4981 actcctactt cttattaact aaagagatgt taaataacta tatttactca tctctgaata
     5041 aaactaataa gcagattgtc tctcagcttg ctattaattg cttcattcta agcattgata
     5101 aggaagaatt ttctaattgc tcctatttaa ttagtaagat aaagacattg ttggacaatg
     5161 aactaaactt ttatgaacaa acagtttttc tctatgcaac tggttacttt gaatttaaac
     5221 gttgccaatc aaccagtgga attgaaaaaa tgaaacaagc catacaagtc ttcgatattt
     5281 taggagaaga taagttaaaa ttacactata ctgaccattt taataaacta gtaaataaaa
     5341 aataaatgaa attattctct atcttttaac taattagtcg taaataatat tattctagta
     5401 aggcattctc gtgaaatttt agaactgtaa atttattggt attaataatt ttcacaaaca
     5461 aatccaatct tctagctatc tcctcatatt tattaatttc attaccaagt tcctgttgta
     5521 attttaaaat atccgtattg agtcgatcta acattattga ttccgtcatg ttcatttggt
     5581 caaaatcata cttagctaat tttctagtct catgatcttc actcttcaaa ttgataagga
     5641 cttccgccat cttgtttaag gtggcgattt tttcttgggt ttcttctagc tgcatatcaa
     5701 tctctgcaat ttctaataca agctcatctt tgatttcttg gtattgtttg ttcgtgttag
     5761 atagttcaat cataagatta atttcagaaa tcttctcttt aagacttttt aaagttggtc
     5821 gtctatatgg gagtttttgg ctatcgttgc tcaattgtct gattaaggtc ctacccttga
     5881 tgaaacaatt attatccctg ttttctttat tataaacaaa gtaagaagac gtttctcgaa
     5941 tgtagacttt atatttttta tgattttatt cttccataat atccaattga tagttgggaa
     6001 tgaaaataag accgctctgt ttgacaccga aagacacctt gatatagacg cccttatcaa
     6061 ctagcttctc tatttggttc tctgcaagtt ccacttcaaa ttcacgaaca gcatctctct
     6121 ttttcttaaa tgtctcaaag gcttcctcga tttcttcagc ggagactttc tccttatgct
     6181 gctcctctcg aaaagtctga aaatcttcct gaagattttc taatgcttga atatctctaa
     6241 cttctctatc ttcaaaataa cgattaaaaa attgaacatc gtacaatttc ttctcactta
     6301 tttttttatg actcaggctt atctttttgc catcttcttc tagggtaaac atcacatttt
     6361 tctgttttaa ctcgatggtt agattcaact ctttagcttt tacatgcaat tcttctaatg
     6421 aataaacaga ctttagtaaa aattttaaac gactttcaat ctcttgtttg gcaaaatatg
     6481 ttttaaaaaa gtcttcatca tataaatctc gtttactaag ttggcgacct cgaattggtt
     6541 ttatcatcgt tctatctgtc atcaaaaaac ggctatgctt ttgactaaaa tcaatctgaa
     6601 catgcaactg ctttgctttc tctaaaaaat catcaaacga tttagattgc tgtagcaaaa
     6661 aataaagacg ttgtttcaat tcaaatttat aactagactg cctatatttt taatagtcac
     6721 ggtaggaata acgcttcccg ataatttttg cccctgccat tttagaaata cgatctgaaa
     6781 tcatacgtaa atttcgttct aaggcataat tccatatcaa ttttttatct gaattactgt
     6841 ctatggcatt gattaggatg tagttgtgaa catgatcttt gtctgtatga gttgctacga
     6901 taaacttaaa gcgacctcca gtcaattcca tcatggtctc ataaccaatg cggttaattt
     6961 cttcaggtgt cagattatct tcaggagaaa atgattggat gagatgatgg gcatgaatag
     7021 tttgttggtg tttttcttgt cggtcatttc tggactcgta caacttgtcg ttattagtaa
     7081 agttaacatt gtacatttct accatttctg catggctagg aaaatctaag taattactca
     7141 tgccaaaatc agatactaat tttagattat ctgttttatc tggattgagg atatatttaa
     7201 tcaaacgcct acgatatttt tttccgtgcg tcgcaaagtg tttagtaact accatgaaac
     7261 tccttcagtc ttttcacctc cacttgaaat tctttgtcca cttccttaat taactctccg
     7321 actcctttac tcaattcttg taattggtcc tgagaaatca gatggctttg attgatcgca
     7381 cgcgcaattt gattgatgtt atttccaata cgtctcaatt caaaaactaa ctggtcataa
     7441 gtatccgtgt taatcgtgac aaatgacata ttgggattaa gcaaaacttt tctggcatag
     7501 actgaaaaat tttgacaatt gctcttagca atccgttcat tcaattggtg taattctgaa
     7561 tctgttagaa atactttttt gagattggta cgataacgat aaaccatagt agcctcctat
     7621 ctcatgtatt tttcacgaaa cccacgactg agtgactgta cttgattgac ttccgcaatc
     7681 aattcttgaa cgcaggtcaa taagattgac acgtgttctt gagtcacttg gtgattctct
     7741 cttgcgataa tcaaaaccaa atgcacatct cgactgatct gttcaaactt ttgagactgc
     7801 caaagggaaa accattcttt ggcagctaac tgtttgtcat caatcatcaa aattttatcc
     7861 ctgacgaatg gtgaaaagtg acgataatta tcaacctcca tcattttttc aatctgtttt
     7921 agctcatctg cggttagatt tacctctttt cgaatgtcac ggtactgttc agacatctct
     7981 tttcctcact ttcatccttt ctcgggtaaa ccccgacccc gtgtgtcata cgggaaattt
     8041 cttaaagtcc ttgttcggtc tttgcgagct caggcattgt ggtcacaata cccaaaaaat
     8101 catatcgcca gctaaccaaa accttccagt tttgacagcc aacgataaga taacttggtg
     8161 gcttcgcccc caaaccccca ggtaaaattc ttagttggat ttttaaaagt tgagaaaagt
     8221 atagcagaag aaatttgggg aagttatcac aaatcaaata gggactaatc tctaacacca
     8281 ctgcatgtac cgtcctatat ttatgatcag ctcccatcgt cactgtcttt tcataccagg
     8341 aattagaatt gacaaattta attagagagg tattcattta attgttcact tcttcgctcc
     8401 atttccatta cagaaatttc ttcaatacta tgtgttcagc tgactcccat gattcgttgt
     8461 actacgtcct aaacgctcac ggaataagcc gtacatcttt cctagtttac tctcgtaatt
     8521 tacgtatata ggttacgaca cctatttgga ttttagagtt cctcatccgc tatatatggc
     8581 ttcaagtcac gattctgttt gtagaacctt gatttcgcta attccttcct atccccccta
     8641 cctcacgata ttcaggctta ggagtcgcta ttggtttcat ctgcagcaaa catccacaga
     8701 ggacttggac ctcagatgta cactatgcct gtcggacaaa gaaaaaagta ggctaaattt
     8761 ctaacctact ttttctgact ctactctgat aaagccgtct catatataga cattttatgc
     8821 ttgaaggaat cttttcctcc ctctaattga ttgatgatat gattttttat atatttttca
     8881 ctaacatatc cctgtgattc aatccatccg ttaactccat ctgactccat aataacaact
     8941 tgatctgtca tagaatttgt tacaattgta gcattatgtg ttgctaaaat aatttgacgt
     9001 tgagctttca catctctaaa ctgctgaact aaatgcctgt aaatataacg attgtctaga
     9061 ttgtcttcag gctgatcaat aatcaatggt ctgaagtctt tagaataatc actatatgct
     9121 aataaaaaat caagcatggc tacaactttt tgtcccaaac ttaatacacc aacttcttta
     9181 tagagaatat caagttgttg cgaagattct ttcgagttaa tattaaactc caaaaataac
     9241 ctttcattag ctacatgctc ttttaaaact cttttaaact catttaataa actactattt
     9301 tcaattaaag agtagatact cttttttaaa tgcgtaatgt tgtattcatt aatttcagat
     9361 ttatctctcc aattattttc ttgttttgca aaattatctt cagagatact ttttaaaagc
     9421 ataaaatact tattagggat attttgtctt acaatgactt taacaaattc tttcattcct
     9481 aattcccgat agataagata taaaacgtct gctacatctt gcatactaat tctataatta
     9541 tcaaacgaag aacgattatt cttgaaaaga taattttcga aatgcggttc ttcccatcta
     9601 tcaatttgtt cataacaaat tcttaactta ccaatctgag tttcattaaa atcctcaata
     9661 attttgagta ttaattgctt ccgctgtttt aaatattcat caagttcctt caattttact
     9721 tcaaacgatt tgagtgtctg agttcttagc ccatagtctg gtctcggtaa ttttttattt
     9781 ttaatcatta aattagaaat aaattctgta attttttcac cgtcagctgt tttaactaac
     9841 tcattaacag aatatctcct atcaaacatt ttctctaaaa ttctagtttt atcaactaat
     9901 ttaaaatggt taccttcaac tttataaact gttgtgtact gagaccgtgt ccattcttta
     9961 atagtgtcag aattaaatct ataaggatag ccaaacttat tctctcgatt ttgcccataa
    10021 tattgtaaaa tattatcctt attttcttgt ttgacatctg gtaaactgac ttcaataata
    10081 tattcagttt cttctaaaac atagagtaca aaagcatttg catggttaca tagaaattcc
    10141 aatttgcttt gcttatcaca atcttgagaa agtacaaatt gtaacatatc aattaatgtg
    10201 cttttccctg tacctctccc tccaattaaa caattcatag atggtgaaaa tgttaaaaag
    10261 aagtctttat ctttttttaa tttatcacct gcaagaaagc ttctattttc cccacgattt
    10321 tctatatata atccttttat ataagacttt tgtttaaagc ttggcttaca taaactaact
    10381 gatacgttat aatcaaacaa tgcttcttga aacatcttga aagaaatttt tccacctttc
    10441 aaccacagat tgttcttccc gagtgaatca atttcgtgag aatcattatc taatagaaag
    10501 ttgggctcac aattaaaatc tgctaatagt ttttttctag aaccttcaat agaatttata
    10561 tttttaactc caataaatcg tgtattttct ttagaaaaaa tttttcgttt atatgcacct
    10621 gataagtgag aacctttttt caaaatgtca taactattga aatgagcaat atagttaact
    10681 attttttgat tattgaaatc cttcattata gtcagtgaat gttgataact tccatctttc
    10741 tcacttataa tattttcact taaccattga ttaacccatg attcttgttc ataatcatat
    10801 atacatacaa tatgcaattt atctgctgca ctaatttcta ctccatgtaa aatatgagga
    10861 tgtatatcat aaatcggata atttttcatt atgattgaga ctgccatttg taacttttta
    10921 atacctttgg tagtattatg atcagttact acaactattt ctattccatt ttttatgatt
    10981 gcctctgcta acataagaaa actaatatat tcttttgaac tagaaaaaac aaccttatca
    11041 aaattactaa aaaaaattgt cttatcaact tttattttct tattttcaaa aaatatatca
    11101 tatagttcat cttcagtaat ttttctatat ttcgttgcag tccaattaga aaatagcttg
    11161 taatcataag aaacaggtgt atgcaaatga attaaagtct tgtgaaagct accgaatttc
    11221 tctttggaat ttgttagttc ttgataaaca gactttatct tgttattaaa ccctctcatt
    11281 tctattctcc taaaaatatc aattgtttat ttttcaagta attcattaag tctcttttcc
    11341 cccacctgca acatctcctt ttctacctga ctccactctc caaacaataa ctcatgaaga
    11401 acatctgctg ctgaagttgt attttctttt gaatcatata cacaacttct atctcgttgg
    11461 taaatttgaa ttctttcaaa aatagctagt tcttccaatt gtcgtgtatt atcaactaga
    11521 tgatttacaa tgaaatcatg atgttctttt ggagttgcgc gtgcttgatt tggattgata
    11581 atgtacagtt cttcataacg gataagagta cttagatacg acaattcagg ctttgtcgca
    11641 attaaggcca attgtacttc atatccctta tttttcaaga gttgtgctgt tttctttgga
    11701 acgtcaatcg ttcgtaaagt tccctctatc aaaagattgt atcccaaatg actcaattcg
    11761 gttactaaag actctaccat ttttcctgca aaatctttgg tgtattctac actgtctttg
    11821 ccatattctt gctgcagttc taaatagtgt ggatgctgag aacgaaaact atcaccatct
    11881 atgataacaa tatttccttg aaattctttc tgtttaatac gatgaattgt agtcttaccg
    11941 gcaccacttt gacctccaag caaaatcgct ataggttgtt tactggactt ttttcctctt
    12001 gtcagtgaac gaagattcct tgctaaagca tgtttgaatt cactatcagt ataatcttgg
    12061 atttccatta agctaccatc cgcttttcag atatctctaa catgcgctca attccatcca
    12121 aatagccgct atatctctct atttcatcaa aattttctac taaatagata tttgtctgaa
    12181 tcaagtcaga tagatcatca ctcattaaaa tccaaggatt agattcatca tcaatgctaa
    12241 ttccctgact atcttgataa cgatagagtc gagataatag attagcacct ctttctttca
    12301 caatttcaat tttcaaagtc aattcataat cttcaacagg attgagcatt ttatcttctc
    12361 ctacgatatc gacataagat acattaaact tctgacaaat gatgtctatt aattcggtag
    12421 agactgaact cgttccattt tcataacgac tcagactatt tcgtgaaata cctacaatcc
    12481 ttgcaaattc gggttgtgtt aagtcatatg ttttacgtaa gaattttatg ttctttccaa
    12541 tcatagcaaa ctcctttatt tttataaatc cattatagca taaaaaagca taacgcacca
    12601 aaaatggtgc gttatttctt gtttttctat cctaaacttt acttctataa aagtcaccta
    12661 aagagccata aatatttatt cttgtattaa ttttttcgat gcgcaaacga tatctacaaa
    12721 tacatctata acgattcacc ttttaggatt tttattgtca aaattgcctt tatctacaaa
    12781 gacaaaatgc ttataaaata gcttgaaatc aaggattatc acctttttcg ttgtagcaac
    12841 actccacatg tgattattag gctattagca aagcgtatcc aatacctcaa taaagtgttg
    12901 tttttactga tattttaact atattgtata gtctactatt taaatctcaa ttaggatatt
    12961 ttatagaata cccaaaattc aacaataact aaaagtaaga ttccattgta tttccttgtt
    13021 ggtctttcat atcacgaatt ttatttttca gaatattaaa gttacaaatt tcatctctaa
    13081 tatcgttatc cgctctgtag ccattaatca tctcagtcag agttttccct ttactaccat
    13141 tctttatagt agtatttact ctttttatac tgctttcaaa aggctcatat gttttatact
    13201 taattacttc gtctttaaaa ttaaataaag gtgtatccgg cttagcattc cataaaataa
    13261 tcaaccacat tatagcatta taaagctgct ttgcagtttc attccacttt tcaggttgta
    13321 aatttccact ccctgtattg tcatattctt gtctattatt tacatgagaa tcacctacaa
    13381 gcggattaaa aagaggtagc cctttgtgat taattagttc taaaaaatcc cttgccgcac
    13441 ccatgcaaca ctgaataact tccttcttgc catcaatttt actctcagcg ataaatacat
    13501 aatattcatc ttcaatagtt gctcctgcat cactatgttt ttgttgattt gctaacagct
    13561 taatatgtgc tttaggctaa acttcaaaat ctctaacaat tctttgtctt gtttcatgtc
    13621 ctctacaatt catttaagtt ctcctttaca agtttagtaa ctagccttat tatactatat
    13681 aagatatgaa atgtaccata atcttcatca actagttttt agaaaatcac aaatccatct
    13741 ggagagatga caagctgatt ctccaattct tggcaattgc ttgctagtgc tactgcttct
    13801 ttctctaaaa gataatcttc tgttgattgg ttgaatattg ctttgaggat ccgtccttcg
    13861 tatttccatt ccagagctac tagatcagat ttgatttctt gaaggctata cttgccatgc
    13921 gaaatgatta ctgacgcgta tttccgaatc ttaatcagcc tcttcataaa gttcagcata
    13981 tcattgtcac ttgatacacg ttcccaaggc atacaacgac gacaatctgg atctggtcct
    14041 ccagtcaagg ctagctcggt tccgtaataa atgcacggtg ttcctttttg taaaaagaga
    14101 aaggctaagg ctgatttaac cagttgaaca tcttcattgg ccgtccacag gattcgctct
    14161 gtatcatgtg aatccaagag attaaacatg acctctgaaa tctgctgctt gtaatacata
    14221 gactctcaat tgatttcatc gatgaactgg tctgtcttct taattcctcg taagaaatag
    14281 tccttgatac tattagataa aggataattc atgacggcat ggaactcatc tccatttagc
    14341 caaggctgag atgtatgcca gacttctcct aggatataaa gatcaggatt tttagctaaa
    14401 actgccttac gaaaatcctt ccagaactga tggtcaatct cattagccac atccaaacgc
    14461 caagcatcga tattaaactc ttcaatccaa taagtcgcaa cctttaaaag ataattcttg
    14521 acctctggat tggctgtatt tagcttaggc atatagtcct cgaaaccaaa aacatgatag
    14581 ggtaagtctc tcttattaac tagcttttca gttgtcactg ggaattgttg aatatggaac
    14641 caatccttat aagcagactg ttcaccattt ttgacgacat ttttccattg aagagattgc
    14701 gaaccaatat gattaaatac cgcatccagc atgactttca tgccacgatg atgcgcttga
    14761 tccaccagtt cccgaaaggt ctccttgtct ccaaaatgac ggtcaatttc aaagtaatct
    14821 gtcgtattgt acttgtgatt gcttgtagat tcaaagatgg gacaaagata tagtccagta
    14881 atacccaagt cttgcaagta atccatatga tcaataatcc cctgtaaatc accaccaaag
    14941 aaatcatcgc tcttaggtgt gacagatgaa tcccagtcta aagtcccttc tgggtttaat
    15001 agagcattgc cattggcaaa tctttcagga aatatctgat accataccgt atttgaaacc
    15061 cagtcaggaa ccttgcaggc atcaatctca tgaagataag gcaacttaaa tccattccca
    15121 attgcatgaa gattttctag agaattttcc acacaccctt tatcgccata caaaatattt
    15181 tgaccttctg tatctctgag ctcaaagaga tactggatac gtgcaaagtc aactgacact
    15241 tcaacctgcc aatggtcaaa taaggtacca gaagttatct tgaccatttc ttttgtatcc
    15301 tgataaaact cctccataaa gataaaaggg tccccatagt gcaagttgat gctttcaatg
    15361 tcccctttct tagttcgaat tcgaatatgg agtttcttat ccttataaag ataggcatac
    15421 tccgactcag gcctatggta aatagcactc aattccatca atttgtctcc taaagtattc
    15481 attcaaattt tacgcaaacg ttttcaaact caatgaatcc agtatactat ttttgtaaac
    15541 tatttgcaag gaatgtccgt tgttaaagga actatctttt aaagtataca aaaagcctta
    15601 aaaaaggctt tctctatata ctaatcctct ttcggttttg aaaatacttc tactcgctga
    15661 gctaggactt tgatttctac aggtaggtta tctgatttat ctccgtcaac atctgactcc
    15721 aattcactat ctgaagagat tttaatatta cgcgttttga tatactcgat attatcattt
    15781 gcgacaacat ccccttttaa taaatcagga atgacggata atttggagaa tatagaggca
    15841 tctttcagaa tcaaaatgtt ggcatagccg tccttgtttt cttcaaagat tttcttatca
    15901 gcgaagtaat ttgtcaaaag gaccaaaaca tggctagctt caccaacata atttccattt
    15961 tctgtctcaa ccttaatgtt aaagacctga tctgtcatga cagacttcat ggtatttaca
    16021 gcataggtta aaataccgaa ttttgttttg tcctctattt caacattgtg aatcgcctca
    16081 ggcagagaac cgatactaaa gatataacca aaatagttgt catttgcttt accgatatca
    16141 atcttattgg ttaaatcaaa atccagttcg tcaattgcgc catcgatgtc ttgattgatt
    16201 tccaaaagtt ttgtaatgag gttacccgta ccgcctggga taatccctaa cttaggaatg
    16261 tagtctctct catcaatacc tgaaatgact tcattgacag ttccatctcc accaaacaca
    16321 accactgcat catactgctc acgagaagct tcttcagcaa aatgtgttgc atccagcgct
    16381 ttttcggtaa ttttggtttc aacatattca aagtattctt ttgctttatt ctccagtttt
    16441 tctttgtaat ccaaagcctt ctcgccacca gaagtagggt tgataattac cattgctttt
    16501 ttcattgatt ttatccttaa ttttaaatag aaatgtttac atttcgtcgt atgcaagtaa
    16561 atgtaatcct attatacaat gaaaatacat aaaagagaaa tctgatgtac tggaaattaa
    16621 tacgctttta ttctattttc ccatcgccta actacatcct ttaagggttc atccaagtaa
    16681 gaataggcct tatccttgat ccaatcagga ataccgtaag ctgcctctgc tatgctacaa
    16741 gtgattgctg cgagagtatc actgtcgcca ccaagtgaga tggcatttct tatcgcatct
    16801 tcgaagtctc tactttcaag aaaggcgata atggcttgag ggacagtttc ctgacatgtt
    16861 tcgttaaaac gatagttagg acggatttca tctaaagttt gagatagatt gtaatcgtat
    16921 tctttttcta tataatcctt aattcgtctt ttacactctg taggattgtc gttaattgat
    16981 tgctcgtact ctctacaata accaccaaag taaaaacgac atagaaagat agcatcagct
    17041 gtagccatag cgcctttgac accttctgga tgattatgag ttacctctgc agaaagactc
    17101 gtaagtcctc tagatgatgg ccatatacca gttttcgcat aaaaaccaca gtccatgatc
    17161 caagcacatg gagaaatacg catagctgat ccattcccaa agctattata aggctcacgg
    17221 ttatcgctgt ttagccatgc attaaaccga gcaccgtaat cagcattcgg atacattctg
    17281 ccatatttct tcatcgcgtc aatgaagtcg tctttttgtc caccattcat aattgcttct
    17341 gcaacagcac aggtcataac cgtgtcatct gtaaaaaagc agtccttccg aaataaagga
    17401 aagtcctttg ttttgatatt gttccattcg taaacagaat cgacaatatc tccaataatt
    17461 gctccaagca tcagattcct ccttgttcat tttgatgctt tttatattgg ttatctacca
    17521 tatttatttt agaaaataac atcctgttgg attttaaaaa tttcattttt ttcaaaatag
    17581 ggttttacca tttctttcca cctagctcta tgaaaattga ttgattttaa aggagatagg
    17641 ccataatttc ccaatgcata accatcattt acttcaacaa caagtgttct gccatcgcga
    17701 gtaacaccga tatctagtcc ataagctatt ggcgcatctt tccaacatga tatcgcttca
    17761 tcaattacac ttgcatcaaa ttgtgcatga taatcacctg tatagggtcg aacatctaat
    17821 acgcgaccat ctaacacaaa acaacgccat tcagctatga attctacaac ctcactaatc
    17881 catataggat agtcgaaagg tagaccaata cctattaaat catgggttcc attaacaacc
    17941 cttccagtaa agacttttga accagcttta ggcttaataa attttcccca attatcaggt
    18001 atattcacaa tctctcctaa aataccagca taaatctttc gaccataaaa ctctttaagc
    18061 tcaataggat agtcataaac cggaacgttt aagcccatca tttttagtaa tgctctagtc
    18121 tccattatat aatctacaac tatatcttca cttgttaact cttttatttc agaaaaagat
    18181 tgatataaaa taacttcttc tccttgtaag caggcaccta cttgagcatt gtatttatta
    18241 attgaaacct cacttggtaa tttactttgt ctaatataaa caaccatttc atcactccta
    18301 tatcactagt gttacaccaa tttgtaaaaa ataatagcaa ttttgctctt atttttttga
    18361 gtaaatagcc cccataatat catcgaaata atcaacggta tttaggagta attcaataac
    18421 ctgggacttt gttagtcgca ttccccttct atctctagca tcttctacta aattttcaag
    18481 tttctctaga tttttatcat ccaagctaat cattattcta tttttatcgg ttgccatttt
    18541 catcacctca agttaattct atcacaggtg taacacttgt gtcaactggc ttttataata
    18601 cattagttta aaagtggaga ggatttttaa cacagtaact ttaaatcttt ggtattaaaa
    18661 aattttcaca atatttatag aaataaaatc tgtctcaaat cagttatcaa atctagtata
    18721 aattatgagc ggctactcta atactttccc tctaaacaag aaaaagactt acactcaagg
    18781 gttttcttcc ccccttcgtt ataacgtttt gactctttta ctagcaaagg tatatactca
    18841 caaggaactt tggttgacta ttgaatctct ccaacttctt ctttaacata tccttctaca
    18901 tcttcaatct ctacaaacat tgggtctaag tgacacaaga aatgccaaac ttcgatccct
    18961 ttttttctgt aaagaatcgc ttcaccgtct tcacttccga aaaagcttct gtcgatttca
    19021 tatccgcggc tttctaagaa gtcttttgct ttacgatagt tcgtttctct tgtttcgaca
    19081 taggctttaa cttcatggtt gttaacgaca tatgcatcaa tttttgaata tccttcgatc
    19141 actctatcat ttttgaggga taaatttgaa atctctttcc aaataatgtt tacattttcc
    19201 tcaggatcga acataaattt agataaagga acaatatttc cgttaaaaat aatttccata
    19261 taatccggta tgtttttagg attaaaatac tccacttcaa aaccatcttc tgtttccaga
    19321 gtgtatcccg ggatttgagc tacaaaggct ttcccatctt ctatggaatc aaatgctact
    19381 aaatctttag aataatcatt ttggtacaat tccaatataa ccatcgataa tctctccatt
    19441 ttcattatca ggctaatgta aataagcacg tcacctgacc aattcaggct ctctgtatca
    19501 tctcatcata tttcctactt actttacgag tcctataccc agaacacacc ttatcgacct
    19561 tcggtctcac ctcgtcgcat tggctgaaca tctactttta cttcgctgat gcttcaactc
    19621 gtacaagcag tgataccgcc tcagcgtgat gcgtcagtgg gactcaaaaa gtttggggaa
    19681 ccttttgagg attaactacg tttctctaat aaacttacac attcaacttg ttcatcattg
    19741 tccaaatcta tgttgagatt ttcttctata attggtagct taaaagtaat ggattttagc
    19801 cattgtccgt tagattgttt ttcttcataa acttgaattt cagaaatcaa agctgaaatt
    19861 aactgcctac gctctacatc attcatgact ttatagagct tatcaaaata gatcagaacc
    19921 ttatatatgt tatctcctgt aagcttttca gcttcaatag tctgtttctt tgctttcgca
    19981 tcaattagtg atgattctaa ttcatctatt ttgtcataca tacgatatag tctatcatct
    20041 aaatcctgtt tccttctctt ataatgctta tcttcaacat ctaaattatc tatttcctca
    20101 attagcttaa actttgtaga atgactcttt ctcaattcct tttggtaatt atctatttct
    20161 ttttctattt cagaggtatc caccttcatg ttgatttttt cttgcatcat agaagcaaat
    20221 ttcggattac ttactatctt gacaatcacc tctgcaacag catcatctaa caattcttct
    20281 ctaatttgct tactgaatgt acacttatga cctcttatca tctgcctatg tttacaacca
    20341 tagtaataaa aatctttata ctttgtgcca tctttctttt tcttgataca cttgttccca
    20401 aacattccca ctccacatat cgggcatttt acaattccag aaagcaagtg tgtgcgtgta
    20461 tcttttcctt tattcacatg ctcatatttc tttgcttgag attttagctt aacctgagca
    20521 gcttgccaaa cttcatcgga aactatagct tcatgtatcc cttcagatat tagatattca
    20581 tcttgttcaa cctgcttata ttcatttctt gtaccatgaa ctttttctaa agttcttctt
    20641 ccaaatgcta ttttcccatt atatacagga ttctttaata tctttcttat aagacctgca
    20701 tcaaacaaag gattcttacc attctgtctt gggatttttc taattccatg attctctaag
    20761 tatttagata tcccattggc tcctatcgta gtatttacat actggtcgaa aatcgttctt
    20821 attgcaactg cctcttcttc atttataaac agcttgccgt cttcaagttt atatccatac
    20881 ggagccaaag ccaccattcc attttccttc ccttgctttt tgaatgcgac cttccattgt
    20941 ttgaatacgg atgttttctc tttctatttc agccacagct gataaaacag aaatcattag
    21001 tttcccagca tctttagatg aatcaatgcc atcttcaacg cagataagat taactccata
    21061 atcctgcatt atctgaagtg tagaaagaac atcagcggca tttcttgcaa atcttgataa
    21121 cttaaacaca agaacaaaag atactccatc ttttccagat tttatatctt ccatcattcg
    21181 attgaactgt attctacctt caatagactt gccagacttc ccggcatctt catactctcc
    21241 aacaatttca taatcgttgt aaatagcaaa agctttcatt cgtgattttt gtgcctctaa
    21301 cgaatacccc tctatctgta ttgacgtaga tactcgtgta tagaggtata cttttatttt
    21361 ttcttttgac atagtattaa cctcaatata atttttctat atcatatata atttttttaa
    21421 tttaactttg gactatcatt tcaagtatat tataacactt ttattagtcc gtctcaattt
    21481 gtgtttttgc catgtcaaaa ctatttttca tctcttgatt ttttgctggc gttggatcgg
    21541 gtagattatc taaatctaaa gcaccagcat attttgcaat cagatttgct attaaatcag
    21601 ccaatccatt ccagtcattg tccaatatat acctcctcta aagttttata tctaataatt
    21661 atttgtttaa ttaagttttt tgacattgac aagtgctttg gattagcaac ataggaatct
    21721 cacctccgcc tctattccgg atgagccggc ttcaacctta gaagtatcat tatcctcatt
    21781 ttcttcatag cggatagggt atccctccct atattcaaac tcttacttat cgctcacttt
    21841 ctttttgctt agcagaactt tttttgtcga attattcagc cgaaagatct tgacggatag
    21901 gttattacgc tccaaaaata attaacgtct tgtcttggtc tattcaattg ttaaggttca
    21961 aaatttatcg agagttatta atctttttaa aatttgacca tcagaaaata tttatcttga
    22021 tgtaacaaaa ttctataaat taccctctta tacttaacag tgaaaagaag tctttcttgg
    22081 taactaattt tgaaatagaa tttgcttata taaaaaggtc caattcccac tgcataagta
    22141 gcagtgaaaa ttagaccctc ttggtaactg tcatctaaaa gtcttctagc atttctttaa
    22201 ttttctaatc gcctttaaag tgtcatattt atattttttt atctctggca tactttgata
    22261 cctttttaga cttaaagtct ttaatagtgc ctttccacct ctttttatct ataaagattc
    22321 tcctacatca taattcattt ttttatttaa acctttctgt cttagtttgt ctttatcttc
    22381 ttcataccat tttaagattg tcacatagtg gttttgatag gtcttaccac tgctttccat
    22441 gtatctggat agtttattta tcattatatc tgtgtgtgag tttaattttt cttttagatt
    22501 tttatattct tctttgctta accttacatt tttgaattct ccataaaaaa tgggggtgga
    22561 ctttttatct atctctccct ctctctcttt atctatctct atatctttct ctatctctat
    22621 ctcttgtcgg acatgggttg gactcattaa ggacaatgtc ctctgtttat tttgtctgta
    22681 tcttctgttt ttctctgccc aggctgtttc tgatccgatt aagtttggta tttcagttag
    22741 gtagtattca tcattttctg ttacaacttc taataagcct tgattgatta aataatttac
    22801 tgttaccatt acatcatcgt ctgtttcatc tatggttagt gctaactctt ttataaaatc
    22861 actttctact ccgtcataat agagtttgcc ctcatctttt aggcttagta gtagaagttt
    22921 taggtagatt atcgtatagg tatctcctcc agatattctc cttaaccttt ttatcctttt
    22981 gtctgtgaaa aattcttctt ttaattttat ccaatagtat cttttgtttg ttgccatatc
    23041 tgctcctttc ttgattttcg ataatcgaaa ttcttgattt ccgattttcg gaattctgga
    23101 cttctgtttt tcggaagtct tgttattatg gttatttaag ggtgtaactt ttcgttactc
    23161 cctttagatt tctctggtca tatctttttt gtttggtttt actttttctt ttactttcct
    23221 ttttcctttt tcttttgtct tatctttgtt tttggatagg tctttgtatt tctttatttg
    23281 ttttaggata ctttcttttt cttttttatt ttccttggct atgacttgct taaaggcata
    23341 ttccattact tttatgtctt tggcttggaa gaatatttca tagtttttgc tttctttgtt
    23401 tttcattact gagaaactta ctccaagttt gtttagttct ttttttaagt ctttgaggtc
    23461 gatttgatct atgcttatat tttctagttg tcctttcttg tagaggtctt ttattttcat
    23521 ttcatcgccc ataagacttt ttaagtttcc atttgctttt tctaaagttt cattcatctt
    23581 ttttcttatt tctttttcta aattgattga ttcttttgtt gcctttattg tgtatgatat
    23641 tatggtttgt gctgcttgac ctgcttcctt gcttatttct tcgtttatca tgcttttctc
    23701 tcctttgttt gaattaaaaa agggaagtat aggttttaat ttttctatac ttccctttgc
    23761 ttgtttttat tttattgttc ttggtggtgg aatactttat tttgatgttt ttatatattt
    23821 cttaggtctt tgtacctttt atacttttaa aaatagctta cactaccttt ccacctttaa
    23881 tagtttatgt gtgttctttt gtctgataga tagtttttca tgttagaata tataatctgt
    23941 atttcttcat tgttcattgc ttttatttct tctgtgcttt tataggtttt gtatgttcca
    24001 tcttcatttg cttttatgag ttcatctatt agctcttgcc ttttattcat ctctattacc
    24061 tcctagatct gactttagtt gtttggtcat attatagctt ggataagata tttttaccag
    24121 gtcttatctt tcttgatcca ttttcttgtt tttcatcatt tctctgtatt cattatcttt
    24181 attgacttgg tcttggaact ttttaatctg tgctattaca cttggttttt ctccctgttt
    24241 tattagctta tctatttcta tggataaatc tataccaagt tctttgttta caaaatctac
    24301 tgaatatttt atatgattaa tttcctggta ttcatctttt atcttgtctt tttctttatt
    24361 tatttcttca agatttgaca ttaaaagaat tttttcttca ttccactttt taggacttag
    24421 tttttcctta tctgatagga gtttttttaa tttcccactt actactttat attggtctat
    24481 atctttctta tgtttgttat aaaatgcttc ttttgtgaat atatttttct tttgatattc
    24541 ttcataaact tcttttttgg ctttgtagat ttcatagtat agaattttct tttctacatc
    24601 ttccatttct ttatggattg tctttgcttt tttatttagc ctataactat tagactttaa
    24661 agtttctatt tttgtttgta actgacctat ggtttctatg ttgttttttc ttaaataact
    24721 atatgcactt gttagctttt tgaagtcata tttttcttta ttagtttttg catatccttt
    24781 tagatattta cttttttctt tttgaatttc tgaataagtt aatagataat ttgttagatt
    24841 aaaaagttta gggttgtcta ttaccttatc tctttctata tccttaaatt tttcataagc
    24901 agtagataag ttatctaata aatttcctat ccaacccttt aatgttttta tctcttcttt
    24961 tattgttttt acaagttgat tatattttct tatttctcta ttatagtttc ccttgtcagt
    25021 ttctattccc tttctttcca ttgcacttgc tgctgatcct aaatggattg tcggtagata
    25081 atctgaattt tgtcttttaa aactcctatg gtctactctt ttttctgctc ctgctctttc
    25141 taaatatttg ttacaaagat ctgaaaaatt ttctctccat ttttctatat tgcctgtatc
    25201 gttccaggtt gttagttcta cttttcttgt ctttggtttt ccatttttgt ttaatacttt
    25261 tctccttttt catctaggat atattctttt tttgacttgg ctaagaactc tcctttttcg
    25321 tttattggtc gcattatggt cattatatga caatggatat ttccattttt atcttgactc
    25381 tcatcatgaa ttgcataatc tactatcatt ccttgtgatg ttaaattttc ttttatatat
    25441 ctttcaacca ggtttttatt ttcacttaaa gataactctt ttggtagtcc tattatgaat
    25501 tgtcttgcta gttgtgcatt agaatttttt tctgccattt ctactttatt ccataaggta
    25561 gacctatcat taaattcttt tggtatatga tcaggcaata ttatattttt tactaatatt
    25621 ttttcttttc ttgtgtagtc atgggttact ccgtcccatt cattttttat tttttctcca
    25681 cttatatatg ctgcacttgc tactgcactt ttgccttttc ctcttgatat tatgtttact
    25741 gaaaaatgaa aactgtctgc catttttatc acttcctttc tttctttgtt gttttaggtg
    25801 gaggcttaat agttttttta tatcctcttt gtgaatgagc gttttgaaat gataaaatta
    25861 aaaaagccga ctactgaatt aatttttgtt gtttcagtat gtcggcttaa ttgttacttt
    25921 catttcaaat tttaaaagtc aagggcgagc cttagcgagt ttatttaccc ttgactttta
    25981 aaaagcgaat ggttgttgct ccctgcaagg gtttgactcc gcaggacgca agcacccttt
    26041 agggtgtata attgcgccct tgtaaccaag ggacaattat gttatttcat ctttagatga
    26101 tttttctaca ttatcatcta ttctttcttc taaaatttcc attatgttta atcttatttc
    26161 ttcatcattt aacgttttta ttaacttata aaattcatct tttgttaaat caatactttc
    26221 ttcaaaaata ctttcttcaa aaatactttc aaacactgca cctttttcta taagtctttt
    26281 gtttcttgct tttctttctt gttcattaag ttttttcttc aactgtcttt tttgattttg
    26341 taattgctta atgctttctt ctttcttttc aatctgttct tcaatactta atcttttact
    26401 tgccatcatg tatcctttct taaaataaaa aacgactaga tttttatttc taatcgttct
    26461 tgttttaaat attataattt gctatattgc attttaattt taagtcttct atatatcttt
    26521 ccatgtaatt ccaatctgga gtacctctac tgtctatcgg taatttaatt ttgatatctg
    26581 gcaatactgt gctagatatt tgatctttat attcagtatt ttttaaagct tgcctaataa
    26641 ttgaagttaa atagaatgct acttctttat tcaattcttt attttttaat tttaaacaat
    26701 gaattttcat atctaggctt gctttatatt tatgataaaa gactgctcct aaaaatgaaa
    26761 cagatataaa attttcaaaa actctataat ttttatcatc tatatcttcg tagtaaccta
    26821 agataccatt gtcaatattt gtagcactaa ttctaggagt ttttccatcg agtaaatatc
    26881 tttttggaat agatgagcct gttggtactt gactcgattt cctctttttt tcggtaataa
    26941 atatttcttt ttattttgtt gtctgatatt tttcctacct gtcctttgta ggatgagtat
    27001 tttctagatt ttcttgaata actttttact tgaagtttta gcttttgaac tagtcgttgt
    27061 actttctttt tgtttattat cagtcctgat ctttttaata ttgctgttat tctctatatc
    27121 ctatttttca ttcatgatat tcttttacta attttatctt aaattctgtg ctgtatttgc
    27181 cattaaaaaa ctgacctcct ttagttagtt ttttggccta acttttgagg gtcagttcaa
    27241 aatttgcgac ttttaaatga attccgatat tcaattatta agagctaaca tggtgcttgc
    27301 caataggaat cattagaggc gaattggaaa tagggtcacg tataattttt gcttcaagat
    27361 taaagatatc tttaactagt ttatcattta gtatatcttc aggctttccc tctgcaacaa
    27421 gtttaccttc tttaattgca aataggtaat cagcgtatct tgctgttaga tttatatcgt
    27481 gcaaaatcat gcaaatggtt gtcttatatt tttggtttag atcagtcaag aggtctaata
    27541 gttctatttg atatgagata tccaagtaag tagttggctc atctaaaagt aggatacttg
    27601 tatcttgggc tagggctaga gctatccata ctctttgcct ttgaccccca gaaagttctt
    27661 caactaggtt atttgctaga ttttcaacat tggccttaac cattgatctg tttattattt
    27721 caaggtcatc ttttccaaga ctcttaaaag gctttctgta ggggaaacga ccacggctta
    27781 caagatcagc tactgttatt gattcaggga ttattggaga ttgaggtaat atagctatgt
    27841 gttttgctaa atctttttct ttataagaat taattgattt attatcaagc aatacttctc
    27901 cctctaatgg ctttataagt cgagacaagg ttttaatgag tgttgatttc ccacaaccat
    27961 ttgacccaat aataactgat attttttctt caggtatttt tatatttata ttttccaaga
    28021 ttattttttc atcataaccg caggtaagat tatttgacca cagacctttc attatatatt
    28081 cctcctgttc atttttatta gtaagtatat taagtatggt gaacctaaca agccagttac
    28141 aacacctact ggatatctag ctggtaaaat attttgagag aatatgtctg ataacaaaac
    28201 tagtaaaatt ccaaccaatc cagctaatat tgggcttctt ttcttgccaa tatttaaggc
    28261 tatgggacca gctaaaaaag atatacaagc tattggtcct gtaattgaag tagaaaaagc
    28321 agttaaagat acagcgcaaa aaattaaaac aagccttgaa agctcgggat ttgctccaag
    28381 tccgattgct atttcttcac caagttcaat aatttctagt cttttattaa aaaataaaac
    28441 taatatagta gcaataatac ttactattag aacaagaggt atgtcatcta actttgtaaa
    28501 agataaagag ccactgagcc atctcataac ttcttgtaat tcatatcttg ctactttcaa
    28561 caataaaaat gaggtgcctg ctcttgtgac agcttgaaaa ccaataccta atattatcag
    28621 tcttgctgct gaaaaaccat cttttttagc tagtaaaaat aatattaaag atgatgttag
    28681 tccacaagtt attgaaataa ttccagtagt taaactattt gtttttaata ccaatatgca
    28741 aaagaccgct gcaatagatg aagaacttgt gacaccgatt atatcaggac ttgcaagagg
    28801 atttcttaac atagtttgaa agataaatcc tgccaatcca aaagaccagc cagctataat
    28861 tcctgctaat aattttggta atctaatttc cataatcgaa aaactagctc caggaacagt
    28921 ttcactattt aagactttaa tcaaagttga aaaagaataa ctttcatctc cgataagtaa
    28981 aatgaaaaat gatagactga ttattattaa taaaaatagt gaggaaaata gtgttattct
    29041 attttttctt ttttgaatac ctataattaa attttgcatt agttattaac ccctctattt
    29101 ttcatagtta cataaataag tactggaccc ccgattattg cagtaattat ccctacttca
    29161 atttcacctg gtttacctaa catacggccg attatatcac atataagcaa gagctctgca
    29221 cctataaaag atgaagaaat ggtcattgtg cgtatatctt tgcttataaa taagccacaa
    29281 aagtgaggaa ctataagacc tacgaagcca ataggtccac caattgcagt aatacttgaa
    29341 cataaaagca cacttgcaat tattgcaagt gatcttatcc tattaacatt aactccaaga
    29401 ccaacagcca tttcatcacc catagctaaa gcgtttaaat ctgatgaaat aaatatagct
    29461 atcaagtgac ctaaaattat aaaaggtagt agtgtagata tagaagataa tgtagctgct
    29521 ccaaggctac ctatttgcca aaatctaaat ttgtctaaga cgttattatt cggtaaaatt
    29581 aaaaaactta caaaactgct taaagccata ctaacacaag ttcctgataa ggctagtttt
    29641 ataggggtaa ggcctgcttt tccgcttaca gcaatcgcgt atacaaaaat tgcacttact
    29701 aagccaccaa tgattgcaaa acttatatgg cttatgcttg atgaaattcc taaaaaagaa
    29761 agaccaatta ctacactaag acttgctcct gtgtttatac cgagtatacc tggatcagct
    29821 attgggtttc tagtaactga ttgcatcaat acaccgctta tggcaagact agaacctgct
    29881 aaaattgcaa aaatagttct aggtattctt ttatatataa ttgatttaat aaaatcatca
    29941 tttgtattgc ccattccaaa agctgctaaa aaatctctga tattaatttc ttttgttcca
    30001 agctttaatg acaaaaatat tgtaataaga agacctaggc agattacaaa aattatgcct
    30061 aggtttattt gttttttatt tcgcattttt gcatgcattt cctaaaatat ttaggtattc
    30121 ttcaatagta tagtttattg aaagtggtgt tggagtgcat gaggctgcta acggtgtatt
    30181 atctggaatt acagcaacgg caccattttt aattgcattt attttaccta aaagaggatc
    30241 tttttgtaaa gcttcaagag ttttatcatc accataagtt atgattacat cagcatcatt
    30301 tatcttattt gcttcttctg cagaaatttc ctttgcaaaa ctatcttcac tctcaaattc
    30361 ttttaatgat tcagggaaaa ctagacctaa atctgttaaa taatttgctc ttggatcttt
    30421 gctagtataa atccagaatt ttgatgtatc tgcagcatta atcatagtaa ataatacttt
    30481 ttttcctttg atttttcctt tgatttctgg atgtttttct aattctttgg atatacgagc
    30541 ttcagtattt ttgattaact catcaccttc tttttccata cctaaggctt ttgaatcaat
    30601 tttaatcata tctctccata aagtttgcca aggtttagat ttgtatgctg ctacaggagc
    30661 aatttttgat agagtgtcat aatcttcttt agttatacca gaataacctg ctaagataac
    30721 atctggttta gaatttgata ttgcttcaaa gttaagtcca tccaaatcgt caaataggtt
    30781 agctttacca tttagttctt tgattttttc ttctgtccat ggtaaaactc ctttatcagc
    30841 acttacaccg taatttgctt ttgaaaatcc aacaggaact attcctaaag ctaatgctac
    30901 atcatgattt ccccaagcaa tagttgcaac tctttcaggt tttttatcta atatagtttg
    30961 accgaaagca tgatctaaaa ctattttatc aggcgcatgc tctttagaag tattttcttc
    31021 atttttaaca gaattagaag aacaagcgct aaaaactata cacatagcta aaatagctat
    31081 tagaaaaaat ttgtttttca taaaaactcc ttaaacatat ttcaagtcta ttgtatcgat
    31141 aataattatc attgtcaata gatgcagtta caaatttaat aatataattt tttcaaaaaa
    31201 ggatctagtt tttattttta gttaaattat gtctatattt ttcattaact catcaataaa
    31261 aatttgtttg ctaatatctc tttcttctga ttttgtttca aggattattg ctacatcatt
    31321 catattttta ggtaaatacc aaccatctgg cttatctgaa tatcccttga agcctaattg
    31381 attaaaagta gttatttgac cagtaccttg attgatgttt tcttcaactt cattaaagcc
    31441 taatacttct cttgcataat ccctaacttg atcttctgtc cttaaagtca ttttctattc
    31501 ctcgtcacta aaattatctt caaaactaat aatatcatta ggagtgcaag ataaagcctt
    31561 acatattctt tctaaattct taaatgtaat tggtttatcc tttcccattt gtgccataac
    31621 atttgttgta agtcctgcca tagctattac atctgttttc tttagtcctt tttttgctaa
    31681 ctgtatccat aatggtttat agttaagtgc cataatatcc ctcttttttt cttcattaga
    31741 tttatttaat tatagcataa atattgattt cattcaatct tacattgatt tagtgatttg
    31801 ttttagagaa tttgttgtgt tattccgtcc ttattttgcc ataaattgtt ttaagtggga
    31861 cctcttatcc ttaccatttt tacctcctaa ttttgagtat aaaaaagacg atagagtttt
    31921 taatttctat catctgagat ttacatatta aattttcatc acaaaataag actctttaaa
    31981 gaatctttaa attcattggt atgctaatta caatatccat tattaaaatg gatactataa
    32041 gcagcacacc aactatttat tttttgagtt ttaaactttg gtagaagtct tgaactcctt
    32101 atatttacat aactatttgc ctctataact attatgacac gaaaccaaca agcaagttca
    32161 agcacctcca tatctttatt caaatgagga ctaagatatt cacaaacatt atcataaact
    32221 tctttatctt ttttcataaa agaggcatac aacttagcaa atttatccta aaattttttg
    32281 ttgcctttat caatcatttc aacgctcctt taaatataaa aatgatccta tcaatcttta
    32341 tattgagcct attttctaat tgataccttg caagaaagga ataatagctg ttcctatacc
    32401 aagtaggaat gtaataaatg cagaaagtca tatactgtca ttcttttcta ttaaatcatt
    32461 ttgaagtgtc tcaaagcatc catgatggct tcttcttttt caggtgtaca ctgtggaata
    32521 atttgtttat cctttttaga cttgttgtaa tgttctcgta attctattcc acatttcttt
    32581 tttatctgtg caatatataa tgtcgaaact tttaattcaa atttattcca aacatattct
    32641 ttgatttgag catatgttgc tttgctctcc gcacttgtca aatccatctc atccagctca
    32701 atttcaacac ttatgtgctt atcgacatcg agtttggaca aaagtgctac cgtctcgacg
    32761 tgatgcgttt gaggaaatag atccaccggc tggactttct tcaattcata tcccaactct
    32821 tggtatagtt taatatcacg cgccatggtt gcgacattgc aggagatata ggcgatgcga
    32881 tcggctcctg tttgggcgct tgctttgata aagctttctg tcaagccctt gcgtggagga
    32941 tcaaccaaga taacggttgg ttgaatccca tctttaagcc aattcttcat agcattttca
    33001 gctgtgtcac agacatagtg ggcgtttgaa atattgttca gctgagcatt tttttactat
    33061 tctcaaccgc ttctggaatc agttcaacac cgtagacttc tttgacatgc ttggcgactg
    33121 ataaaccaat ggttccaata ccagaataag catcaataac cacgtcatct ttttttaact
    33181 ctgcaaagtc aatggctgtt tgatagagtt tctccgccat ttcagtattg acttggtaaa
    33241 aggctgggcc agcgatttgg aagtcatttc ccaacatctg gtccgtaata tagtcttgac
    33301 cataaagagt gcgccactcc ttaccaaaaa tcgcattggt attctggtcg ttgatatttt
    33361 gcatgacaga cacaatctct gggaactgct tgataacttg ttcaatcaat tggtcaacac
    33421 gaaaaacttt tggacgagtt gtcaccaaaa cgaccatgat ttgtcctgaa tagtgaccac
    33481 gacgcaccac aagattccga atcaatccag actgttcctt ttcgtcataa ggttttaaat
    33541 caaaacgacg gagcaggtct cgaagagcta ctacgacttg gtcaatgaca ggatcctgga
    33601 taaagaaatc ttcaaggggc atgaggttgt gcgaattctt acggaaaaat cctgtttcca
    33661 agacaccatt cactcgacga acgggcacct gcgccttatt gcgatacttg actggatgtt
    33721 ccataccaag cgtttcagca acttctacat ctgcaattcc agcaatcttg tagagactgt
    33781 ccttgacttg cttggtttta aacttgagct gttctggata agaaaggtgt cctaaatccg
    33841 cgattcctga acgcaggtaa gccaaatcta gatcttgatt acggtgtggt gactggacaa
    33901 ggtatttttc aacttttcca aagccaatct ttttattgac cttgaggaca cgcatgagaa
    33961 ttttttcact cggtaaagca ttctctacaa aaaagaccaa accatctacc ttggcaactc
    34021 ctgccccttc atgggtcaaa tcaacaattt caacttctac aatatcattt ttctttaaca
    34081 ttcttttctc tttctattgg ccgacaaaaa agacggcaac gttacggtta ccatccatta
    34141 taccatgaaa tttcttaaga accaaaaccc ttgaagaagt tgacaagggc ttgccagagg
    34201 gagcttaaga agttaccacc gtcctctagc gccttatccg catcaaagtt aaggttgata
    34261 tttttaaaac tgtcgccagc ttgtgatacg atgctttgtt taaggtcatt tagggtttta
    34321 gtgaaatctg cattgctgag gatatcactc tttgagagat tcaaggcaaa attgatgatg
    34381 atattgatct ggtttcctgt tatgacctga tcaagtttgt aattttttaa ggtatcttca
    34441 acaatcttgc ggatatcttc ttctgtcaga tttcccttgc tttctttagc tttggcgagt
    34501 cctgacttga tatcagctag ggcaacgttt aatttattag catcataacc tgatttgtcc
    34561 ttgttttcag cattgatatc tgacaaagcc tttagctctt cttgagccaa atctttattg
    34621 gcttgcggca ccttggctcc attagcttct agcgaatagt agatcccagc caaagcactc
    34681 tcacctgtaa ctggaatggg tgctgctaca gtgattttgg cgtgttccac acccaaagtt
    34741 acggctgcat ttcggtacat atcctgagtt accttagtga tgttttcagg tgtttcaatc
    34801 ttgacctcaa gtggcgattt gtcacctagc ttttgaatct tggctgatga atacaactgt
    34861 aagctagagt cattggccac attcatgatt ttagaataaa catcaggtgt catggtcttg
    34921 agttctttgg tatctgttga ggcattgtag cccagttttt taagagtttg atttttttgg
    34981 tcttcagata gggaagaacc taggacatat tcaggttgga cataggtttc atcgataact
    35041 ttttgaacat ctgttgctgc atggacgcta ttcatagctg ttactgccca caagatcgca
    35101 gcgctagtca gaaagagttt ctttctcata gggaatttcc tcctttactt ctttagagta
    35161 atatatctat cttaaagaaa acttataaca aaaacacctg gtctagccag atgttgaaaa
    35221 gagagtgaaa catttgatga tgtaaaggtt aagtcgtacc tgtctagaat aataatagtt
    35281 tcctccattt acatagagtt cagcaccgtg aaaaatggaa atggggtgaa tataactata
    35341 agtctttcca gtcctattac caagcaaggg ggcaacagtc tcacgagagt actgtttggc
    35401 tagagccaag gtattttcct tgccattttg ggcgataaaa tcgatatagg caggtccaaa
    35461 attataggct tgaacagctg tccagatatc tacacccttc ttctgcgcca gatagagatt
    35521 gcctgtcaga gtttgaatgc cttgccgaat gctagaggca ttatcattga tggtgttggt
    35581 ggaaccactt gcagactcac tagactgcat aacatcgcct tcttttcctt ttgtttcagt
    35641 ataaatcata gcaagcacaa gctcttcgtt tgctggggtg tctttttcac tcaatatttc
    35701 tcgcaccatg ggttgatagg tcatgacttg tttgacatct tgatgaacgc ggtaagcttt
    35761 atagccagca aaaaggaaga ctgctagtac aagcactctt cgaattcgtt taaacattat
    35821 ttactttgga tatcctcgat atttttgatt aagatagagt aggttccatt ttcgttttgg
    35881 ataaactcaa cagactcggc gtcttgatag acgttattgg gaacgatgag ctcaattcca
    35941 tttgataagg agagtttttg gttttcaaat ttctttaatt ggcgactggc atcaatttca
    36001 tcaaattgaa caggttctgg tacggcttct ttgacttggt caataaagct caaacgagcc
    36061 gtcagattgt tgtcaaaaag gtcattagcc aatttctcag gtgacaattc attgctttct
    36121 tctaggttgt tgaaaatagc tgatttgacc ttggattgaa attgaaaatc atctgtgtta
    36181 aaagattcag caattctctg ggctgttttt tccagttcct tgatagattt tttaggagaa
    36241 atcttaggag cgacagcaag aagattatct gaaaaatagt tcaaaaaagt cccgttgtac
    36301 ttgattcgtt tttcaatcag gtgatacttg cgactctgaa gattgaccac caaggcctca
    36361 tcagctcccg ttccaaatcc aggcaggtta ttctgagtca gcttgattgg attatcaact
    36421 tctcctccga ggtgggtcaa ggtctcccgc agggcaattc gcaagaaagc gaaatgttct
    36481 acaccttctt tagaaaattg aacaaaaatc aagtcattgg tcttgagatt ttcagaaatg
    36541 ctaaactcct ctttccagag attagccagc gttactgatg tctccaacaa atcgtctgta
    36601 atatgattga agaagggatt ttcttcttcg aaaatcccag tcttggcttc atctgaatac
    36661 acatgttcaa tttttttacg taggtattct tcgatttttg gagtaatatt gagaaactta
    36721 tctgctaaga acagctcggt atcatccgga ctgaactggt gaataatggc tttcttaata
    36781 taaatatcca taaaagtttt agtcctcgta taatgggaag gcatctgtca attctttgac
    36841 tgcacttctc acttcttcta atacagcctc attttctgaa ttcttaaggg ttttaatgat
    36901 gagttcagcc actttgcgac tttcttcttc accaaatcca cgtgcagtaa tagctgctgc
    36961 tccgatacga atcccacttg tcttgaatgg cgacaaggtt tcgtaaggga ttgaattttt
    37021 atttagggta atattgactt catccagcaa gttttgagca acttttccgt tttctacaac
    37081 cttagtcaca tcaacaagga agagatggtt ttcagttcca cctgaaataa tacggaaatc
    37141 agggtcttgc aagaagacat ctgccatagc cttgctgttc ttaattacat tggcagcata
    37201 ttccttgaag gctggatcca aaacttcttt gaaagaaact gctttagccg ccacaacatg
    37261 ctctaaagga ccgccctgaa tacctgggaa aatagctgaa ttgatttttt tagcaagttc
    37321 ttcgtcattg gtcaaaatca aaccaccacg aggtccacga agggttttgt gggtcgttgt
    37381 tgttgtgata tgagcgtatg gaactgggct tggatgaagg ccagccgcaa ccaaaccagc
    37441 gatatgggcc atgtccacca tgagcttcgc accgacagca tctgcgattt cacggaattt
    37501 tgaaaaatcg ataatttgag aatatgctga agcaccagct acaatcagtt ttggttttac
    37561 ttcttgggct tgtttcaaga tagcatcaaa gtctaagagt tccgtttcag gatcaacact
    37621 ataagaaaca aagttgtagg tttgaccaga gaagctaaca ggagccccat gagtcaaatg
    37681 accacctgat gccaaatcca ttcccataac cgtatcacct ggctcaatca aggacatgta
    37741 agccgcacag ttagcttggc ttcctgaatg tggttggaca ttggcaaatt tagcaccgaa
    37801 aatttctttt gcgcgttcaa tagcaagagt ctctacaacg tctactacat cagttccacc
    37861 ataataacgg cgtcctgggt aaccctcggc atatttattt gtcaagatag acccttgagc
    37921 tgccataaca gccttggaaa ctacgttttc cgaagcaatt aactcgatat tattttgttg
    37981 gcgttcttct tctttggcaa tagcattcca gagatcagca tcatatgctt taaaatcatc
    38041 tttgtcaaaa atcataggtc ttctccttta ttgtgtgact agtccattag tttgatttta
    38101 caataagaaa atcaaactaa cagatgcgaa taaaccgttt ctgcatttta tcacaagtat
    38161 agccaacttt ttcataaaat gcatgagcac ccagacgatg attggcagaa tttaagcgga
    38221 taaacccata accacatctt tttgcttctt cttccaaccc ttgtagtaaa cttttaccaa
    38281 taccttgacc ttgcgcttga ggtgaaactg ctaaagctaa gatattaaat cctgctttag
    38341 aatagagtga ttcgtaaact tcagcgtgga catatccaag taagacatga ttagctgcat
    38401 cctcatagcc aagtaggaaa tgatgggaat cctgagacag tctagctagt tggctagccg
    38461 tttcctctgg actaaaagta taacccaaag cctcttggtt gatgtcacat atcgctttca
    38521 catctgtttc ttgcaaatct cttagcattt caagcctcct caaaagaaat ctctggcaac
    38581 cgagcaagaa tatcttctcg tttaattgcg ccttggcgta agattttcac cttgtctcca
    38641 gacaaatcca caatagttga atcctgtcca gttagaaaag catcgtcttc cagacccaga
    38701 acctcttggt caaaatcctt cagaatttgt tcaaaggtta caccacttgc ctgacctgag
    38761 atattggcag acggcccaat caagggacct gtctctcgaa ttaaatccag tgtgataggg
    38821 tgactgggca tccgaaatcc aatagttgca aggtcagaat ttacccaata gggaactcgg
    38881 tcattggctt cgagaataat ggtcaaggga cctggcaaaa aggtctctac aagtttttgt
    38941 agataagctg gctgattctt tgaaaagtgc aagatgtcct cgaaagaggc gatattgaga
    39001 ttgagtgcct tatctctagg acgacgtttg agttggtaaa catggtcaac tgctttttca
    39061 tctaaggcct tggaaaaaag accataaacc gtctctgtag gcagaatgac agctccacca
    39121 ttttccaact cttgtctaat cctgtccatc atcaaccacg accatcctat cttgaccaaa
    39181 ttggtccttg agtgttcgaa ctcttttttc aggaagatgt ttcctaaaaa gttcgggaac
    39241 actttgacct tgcttgtatc caatttcaag gtaaatctta ccactatctt tgagatagtc
    39301 tgttgcatct tccgcaattc tacagtaaat agctaggcca tcctcgtctg caaagagagc
    39361 tagatgaggc tccgaatgca aaacattcaa gcctacctct gactcatctt cacgagagat
    39421 atagggtgga ttggatacaa ttatatcata tttttcagaa atttctgcaa aacaatcaga
    39481 ttttttaaaa aatatattaa gattttgatc gctagcattc tctgatgcaa gctctaaggc
    39541 ctcttgagaa acatctgctg ctgtcactga ccaagctggt ctattttttg ctagagcgag
    39601 agcaatagct ccactacctg ttccaatatc cagaactgag agattcgtct caagattttc
    39661 agttagaata agctccacta actcctctgt ttctggacga ggaatcaaaa cccgttcatc
    39721 cacctttaaa tgcattccat aaaaatctgc ctgtccaatg atgtactgag ctggcttgtg
    39781 agctgctagt tgctggtaaa tatcttctac aaattgtttt tcttcctctg ttgtcacctc
    39841 ctgctggagg gcaaaaataa agtctgtaaa agatagattt ttcagactac gatagacaaa
    39901 agagaggctt tccgcttcct ctccttgtct tatcaactct tcttcaaaat ttgaaaataa
    39961 ttgagctaat ttcattattt gtttaattct tctagttttt gtgtttggtc ataaagcacc
    40021 aaggcatcca caacttcgtc caatttacca gacaaaatcg tatctagttt ttggagggtc
    40081 aagccgatac ggtggtctgt gacacggttt tgtgggaagt tataagttcg gatccgttct
    40141 gaacggtcac cagtaccgat tgtcgactta cgctcagcgt cttgttcatc ctgagcaatc
    40201 tgagcaaagt ggtcagcgac gcgtgcacgg ataatcttca tagccttctc gcggttcttc
    40261 tgctgggtac gttcttcctg catctcaacc ttgatattgg ttggcaagtg aacgatacga
    40321 acggcagtcg caaccttatt gacgttctgt ccaccagcac cagaggcgtg atagatgtcg
    40381 acacgaaggt cttttggatc aatgtcgtat tcaacctctt caacttctgg cataacaaga
    40441 actgtcgctg tcgaagtatg aacacggcct tggctttctg tcacaggaac acgttgcaca
    40501 cggtgggcac ctgattcata cttaagctta gagtatacag actgacctga aaccatagca
    40561 accacttctt taaaaccacc gacaccattc atagaggctt ccatgacttc aaagcgccaa
    40621 ccttgggctt ccgcatactt ttggtacata gttagcaaat ctccagcgaa aagtgccgct
    40681 tcgtctccac cagctgctcc acggatttca aggatgatat tcttgtcatc gtttggatcc
    40741 tttggaagga gcaaaatttt cagtttttct tcatattctt ctttttcagc cttggcatct
    40801 ttgagttctt gcttggccat ttcttccaag tccgcatctc cgcctgattc cttaatcatc
    40861 tcttcggcat cgacgatatt ttgaaggact tgtttatact cacggtaggc tattacggtg
    40921 tcacgattgg aagcttcttc ttttgaaagc tccataaaac gcttggtgtc tgaaacgaca
    40981 tcagggtcac tcagcaattc tcctagttct tcataacggt cttctacagc ttgtagttga
    41041 tcatagatgt tcattttttc tccttatttc tcaattgtta aatcatagat tgctactact
    41101 tcattctcgg atatttcccc agtttcttta aatccataac tgagataaca aaatcttgcc
    41161 tgttcatttt ctggttcata agacaaccaa agtttattgc ttaaacctgc tggcgctgtt
    41221 cgaacatagt ctagtacttt atccataatt ggtttaaaat atccttgatt ttgaaaattc
    41281 ttatcaatca taaaacgaaa tagtaaataa tttccactac taattccgat ctttttatca
    41341 taagctatca tcacaaaacc tataattaca tcattatcat aaactgccaa tggagctaca
    41401 aaatctccat ttttagtgta gacgtatgct tcagctaaac taattgcgtt ggttgcaatg
    41461 aattgttttt gatattcctt gacatccaaa tttaaaacat caaaataatt ttccattgta
    41521 acatctctta gttcaattgt catagttttg ctccttgtta gaggttatca ttggcgcaaa
    41581 ataatgttta cggcaaaccg agatataggt ttcattacca ccaatctgga tctgttctcc
    41641 atcgtaaacg ggcagtccat cctgtgttcg caacaccatg gtcgcctttt tcttgcaata
    41701 ctgacagatg gtcttgattt cgtcaatctt gtccgctaaa agcaagagat atttggaacc
    41761 ttcgaacaat tcattgcgaa agtcattttt caagccaaaa gccatgacgg gtatgtctaa
    41821 ctcgtccaca acacgagcta ggtcgtaaac atggtggcgt ttaagaaact gggcttcatc
    41881 gaccaaaaca cagtaaggtt tttctggtag gtctcggata tagccaaaga tatccgttgt
    41941 ttcctcaatc gcaagggcag ggcgtttcat gccaattcga ctcgacacat agccaacacc
    42001 gtcacgcgta tccagagccg aggtcataat gacaacacct tttccttgct cctcgtagtt
    42061 ataggccact ttgagaatct caatcgtttt accagagttc atggtcccat aacgatagta
    42121 caactgtgcc atgtttcttg cttcacgtcc atttctaaat ttttgctaca ttctagtata
    42181 tcataatttt cttaagcttt aaacggcaaa atgtggtaaa atggaagaaa tcaaaactag
    42241 tggaggaagc tattatgcca tttgtacgca tcgatttatt tgaaggacgc acgctcgagc
    42301 aaaagaaagc tcttgctaag gaagtaacgg aagcagttgt ccgcaacact ggagcccctc
    42361 aatctgctgt ccatgtcatc atcaacgaca tgccagaagg aacttacttc ccacaagggg
    42421 aaatgcgtac taaataagct agcttaagca gaattgctta ggctttttca atctccaagt
    42481 agcattcatt gaagaaatat cctaaatttg ttacaatttg aaaagaaact tggagaattt
    42541 ccaagaaaag agctattaat taaaggaaac attatgatta cacgtgaatt tgataccatc
    42601 gctgctatct ctactccact aggtgaaggg gctattggta ttgtccgcct gagcggaaca
    42661 gacagttttg ctattgcgca aaagattttt aaaggaaaag acttgaacaa ggttgccagc
    42721 cacactctca actacggtca cattattgat cctctgactg gtaaagtcat ggacgaggtt
    42781 atggttgggg ctatgaagtc tccaaagacc ttcactcgtg aggatattat cgagattaac
    42841 acccacggtg ggattgcggt gaccaatgaa attctccagc tagctattcg tgaaggggct
    42901 cggttggcag aacctggtga atttaccaaa cgtgcttttt taaacggtcg cgtagacttg
    42961 acacaggcag aggctgtgat ggatatcatc cgtgccaaga ctgacaaggc catgaacatt
    43021 gcggtcaaac aattagacgg ctccctttct gacctcatta acaatacccg tcaagaaatc
    43081 ctcaatacac ttgcccaagt tgaggtcaat atcgactatc ctgagtatga cgatgttgag
    43141 gaagccacta ctgctgttgt ccgagagaag acaatggagt ttgagcaatt actaaccaaa
    43201 ctccttagga cagcacgtcg tggtaaaatc cttcgtgaag gaatttcaac ggctatcatt
    43261 ggacgtccca acgttgggaa atcaagcctt ctcaacaacc tcttgcgtga ggacaaggct
    43321 atcgtaacag atatcgctgg gacaacacga gatgtcatcg aagagtacgt caacatcaat
    43381 ggtgtacctc tcaaattgat tgatacagcc ggtattcgtg aaacagatga catagtggaa
    43441 caaatcggtg ttgagcgttc gaaaaaagcc ctcaaggaag ccgacttggt tctactagtg
    43501 ctaaatgcta gtgaaccact aaccgcccaa gatcgccaac tcctagaaat cagtcaggag
    43561 actaatcgca ttattcttct taacaaaact gacctgcctg aaacgattga aacttcggaa
    43621 ctacctgaag atgtcatccg catttcagtt cttaaaaatc aaaacatcga taaaatcgaa
    43681 gagagaatca acaacctctt ctttgaaaat gctggtttgg ttgagcaaga tgctacctac
    43741 ttgtcaaacg cccgtcacat ttccttgatt gagaaggccg ttgaaagcct acaagctgtt
    43801 aaccaaggtc ttgaactagg gatgccagtt gacttgcttc aagttgactt gacccgtact
    43861 tgggaaattc taggagaaat cactggagat gctgctccag atgaactcat cacccaactc
    43921 tttagccaat tctgtttagg aaaataagaa aaatccatga tccttcattc ggtcatggat
    43981 tttattgtct ttattagtaa tctggtctta agacccctgt tacagttgcc ttagttgctt
    44041 cgtagtcgcc atctacgaca accttgataa tgcgtttggc atcttcttct ggtgctggaa
    44101 taagaggtag acgagtgggt ccagcttcaa atcccatata gttaagaact gccttaactg
    44161 gagcaggact tggataagag aagagagcat taaccttagg aatgaattta cgctgaatag
    44221 ctgcggcttt cttcatatcg ctttctgcaa tggcagtaaa catctcgtgc atttcatccc
    44281 catttgtatg agaggcaaca gaaataaccc catccgcccc aaggttcatg gcatggaaag
    44341 catctccatc ctcacctgta taaatcaaga actcttcagg cttgtgctca atcaagtaag
    44401 ccatattagc caagctagta cattctttga caccgataat atttggatgg tcagccaaac
    44461 gaagcatggt ttctggagtc aattcgacaa ctacacgccc tggaatgtta tagataataa
    44521 ttggtaggtc agaagcatct gcaatagcct taaagtgctg atacatccct tcttgagaag
    44581 gtttgttgta gtaaggaaca atagcaagcc cagctgcgaa accaccaaat tccgctactt
    44641 ctttgacaaa ctcaatagag tcacgcgtat cattagtacc tacacccgca atcaaaggaa
    44701 cgcgtccatt gacaaccttt tgtacagccg caaacaactc caactcctca tcgtgggtca
    44761 aagttggact ctcagcagtc gttcctgcga gaagaattcc atccgtatga tgggccaata
    44821 aatgctcaat caaggctgga atagcatcaa agttaatgga accatcctca tggaaggggg
    44881 taataaaggc tgtaatgatt ttacattttt ttaaatcttg ataagacacg aaaacacctc
    44941 tctatttcaa agaaggagtt catctgaact cctaaacgat atgactattt taattcaaat
    45001 ttcaattcgg ctgttggacg aaccaatcca cgttcatgaa gagtttcagc aatctgaact
    45061 gagttccaag cagcaccttt gagaaggtta tctgaaacaa cccacatgtg aattcctttt
    45121 tctgcatcca agtctttacg gatacgacca acaaaggtat cacgcgaacc aactgcattg
    45181 atagcttgag gatagatttg atgagctaca tcatcttcaa gaacagcacc tgggaaggct
    45241 gcgatagctg cttttacttc ttcgattgga gccacttctt ttgtttcgat ataaacagac
    45301 tcagagtgag ctgacaagac tggaatacgc acacatgttg cagatactgc aatgctatca
    45361 tcttccataa ttttcttagt ttccttggtc atcttcatct cttcgtacgt gtaatcatta
    45421 tcagtgaaaa catcaatttg tggaagagcg ttaaaggcga taggataatg tttcttgtca
    45481 ccacctgaag gcaagatttc cgcatgcaaa tcacgtggtt tcacaccatc attcaagact
    45541 tcacgaagtt cacgttgtgt ctcaagaatt gctcccatac cagcacctga aacggcttga
    45601 taagttgaaa caatgatacg gtccaagccc catttttggc gaaccggctc aagagccacc
    45661 atcatttgaa ttgttgaaca attagggcag gcaatgattc cgttgtgagc atcaagtgca
    45721 tgagcattga cctctggaac aaccaaagga acatctggat tttgacggaa ataagatgta
    45781 ttatctacta ctaccacgcc agcttttact gcgtatggtg catacttagc tgatgtagaa
    45841 ctacctgctg aaaagagagc aatatcaact ccttcaaaag ctgtttcagt cgtttcttca
    45901 attgtaatat cttgatcttt aaatttcaat gacttacctg ctgaacgtgc agaagcaagg
    45961 taacgaattt tatcgattgg aagtgttgat tcttccaaca tttttatcat ctgagcaccg
    46021 acagcacctg tcgcgccgac tacagcaact gtatatccca taaataacct ctttcggaat
    46081 tttctaaaaa tttctataat agaagtatta tactactttt tccatgaatt gcaaagcttt
    46141 ttcatcattt tttggaaaat aaaaatccca gtcgctagac tagggactaa gaggcatctt
    46201 catgtgatga gcaggttcac acaactcatc aaggtccgct cctgcgttat gacctcctta
    46261 tgctcaatag tagtccgaag actacctatc gactcatcgc atattctata ttactagaga
    46321 tacttgattt tgtcaataag aaattttttc gatcgagtat aacaaaaaac tctcgtattc
    46381 aagagtttcc ctatacatat catgctaatt gccgggattg aaccggcgac ctcatcctta
    46441 ccatggatgc gctctgccaa ctgagctaaa tcagcttact taagaagtat actatattca
    46501 gaaaaacttg tcaagtttcc ttagaaattt tccataggaa aaagccaggt aagaactacc
    46561 tagcttatct tcttctattt acttaaatca attcgacgac caattttacc aataataatc
    46621 gccccaataa tcaatgaagc aaattcaccg attcctgttg taaaccaagt aaggaagaat
    46681 ggtaattctg ctacaatatt taactctgca gcgatagtaa acatggaaat tgaaaagagg
    46741 attgaaaaga agaaatgatc ttttcgaatc aatccgttaa agaggtaatc cttgctatat
    46801 tttgcaaaaa gccaaacacc taaactgagg aatactaagg ttgaaccacc accaacaaag
    46861 acatctagca gtccgaagct aaagaaatta gcaatcatac aaccgatggt aactccgatg
    46921 atgtacttag gattgtaaaa agccataaag ttcatcattt ctgaaatacg aaactgataa
    46981 gcaccatagc tgatggcatt taggggcggt gtgacagtca aaacgacgta gatagcagcg
    47041 acgattgcaa tatctgcaac atcacgaata gttaattttt tcatcttttc tcctttggcg
    47101 gttgcccgcg tgtaatatgc ttggtgaaag aagataagca ccaagggttg ctttattcaa
    47161 ccctactagt atagcacaat agcctgcttt atgctatact taacacatga aaattcctat
    47221 tcaaaaattt tttaacaatg aaatcttagc ctatctcttt tttggccttg cgacaactct
    47281 agtttcgatt ctctcacgac tagtcattta tcaactaagt catcaggaac tcctggctac
    47341 tgccctagca aatattatcg gtatcctatt tgcctttatc acaaatgata cgattgtatt
    47401 taagcaaaaa aagaaaaata gacttatccg tttagtgaaa ttttctcttg ctcgcctttc
    47461 tacttttctg ttagacttgt ttttaacttt tctctttgta acccaatttc ctcacatcat
    47521 agggcaattc gtaactgaaa acattgataa gataaatgct attgaaacaa taattgcaca
    47581 aatattcatt attatcatca attatatctt gagcaaggtc tatattttta gaaaataatg
    47641 ctccatttat gagcctttta attgccttct ataatgattt aggatacaat gaaacacgaa
    47701 acattgaaag gaaaacagta tgttaaaaaa tctaaaatcg ttcttgcttc gaggaaatgt
    47761 tattgacctt gctgtcggtg ttgtaattgc ctctgctttt ggtgctatcg ttacttcact
    47821 tgtaaacgac attatcactc ctcttatttt aaatcccgct ttgaaagctg ctaaagttga
    47881 acgtatcgct caactttctt ggcatggagt cggctatggt aacttcttaa gtgctattat
    47941 caattttatc tttgtgggta ccgccctctt ctttattatc aagggcattg aaaaagcaca
    48001 gaaactgact ggcataaagg aagaaaaaac tgccgaaaaa aaaccaaccg aattggaagt
    48061 ccttcaagaa ataaaagctc tccttgagaa aaaataatcg attaaaagga tctagcgcaa
    48121 agctaaatcc ttttttcttt actctttggg taacttgcct gctttttcaa gcattttttt
    48181 gataagataa ggcatcttaa cattctcccg cccttttttc tcaatcagtt ttttcacaaa
    48241 ttctggcatt tgtaaatctt cagattcagc caaaatgttt tttgtctcgt ctgaaggaac
    48301 taactcatca aaggtctctt cttctgggag aaattcctta aactcttgat tttcattgac
    48361 tctaactgta ttgaccaaag catcaatcaa acgagaatct gtatttggca ttggtggacg
    48421 atggtagttt accccaaatt cctgacataa atcataacat tccacatcat tgtcaaacaa
    48481 gacctcaata tgctcactga tgaaactaat aggtacaaaa atataatggt ctggatgttc
    48541 tgtctgttct ctgagatact ccaaaacatc tggtttaatc catggaatac caatatcact
    48601 ctcactctgc caagtgttag tatattgttt tgaactcaag cccagttttt cagcgactag
    48661 cttgctattt tcgaaaattt ggtctatata aggatcacca aagtccaagg caaaaatagg
    48721 cacactatgg gctgaaaaga tgactttaaa gctgtcttgc tttacttctt cttttaaaat
    48781 cttagcaatt tcatctgccc aatagtttaa gagcgcttct tcctgatacc agtccttaat
    48841 gaccaaaaat tgaatttgtt tgctttctaa aaatttttca tagcccatga cagagtagaa
    48901 agaataatgg ggctccaaaa tcaagcaaat acactgttca attccgtctg cttccatttg
    48961 accgatcaca tctggaataa agggactgga aaacttatta gcaaagtaga cactgtattc
    49021 attccccagc ctagcttcta ccaaggcaac ctcttgacgg gtaatttttt gcagaggcgt
    49081 gcctccaatt cgtacataat tatcatagag agtctgaatc tcgtggtctt ggggtctcac
    49141 cccacgacga atatttgtga aaaaatcagc tacaccttca aaggtaatct cttctggtga
    49201 accgaaggtc atcattaaaa ttgctttttt catgactgct tccttgtgat gtttttatca
    49261 agtttatttt atcattaatt catcgataag taaacgctaa cataggggca ttctcaatct
    49321 tctgtctttt gtttttctct tctttctatg atacaatgga aaaaataaat tcaaaaggag
    49381 tttttttatg acttatccaa atctcttgga ccgcttctta acctatgtta aggtcaacac
    49441 gcgctctgat gaacactcta ctactactcc aagtacacag agtcaggttg acttcgcaac
    49501 aaatgtccta attcctgaaa tgaaacgtgt tggactgcaa aatgtttact atctaccgaa
    49561 tggttttgct attggaacct tgccagccaa cgatccgtct ttaacacgta agattggttt
    49621 tatatcgcac atggatactg ctgattttaa tgctgaagga gtcaatccac aggtaattga
    49681 aaactacgat ggtggtgtga ttgaactagg gaattctggt ttcaaactcg acccagctga
    49741 cttcaagagt cttgaaaaat atccaggaca aacgctcatc acaacagatg gaacaagctt
    49801 gctaggtgct gatgacaaat caggaattgc tgaaattatg acagccattg aatatctaac
    49861 tgctcatcct gaaattaagc actgtgagat tcgtgttggt tttggtccag atgaagaaat
    49921 cggtgttggt gccaataaat ttgatgcaga agattttgat gtggattttg cctacactgt
    49981 tgatggtggt ccactaggtg aacttcagta cgagactttc tcagccgctg gtgctgaatt
    50041 gcatttccaa ggccgtaatg tccaccctgg tactgccaaa gggcagatgg tcaatgccct
    50101 tcagctagca attgattttc ataatcaact tccagaaaat gaccgacctg agttaactga
    50161 aggttaccaa ggtttttacc atctaatgga tgtgacaggt agtgttgagg aggcgcgtgc
    50221 aagctacatc attcgtgatt ttgaaaaaga tgcctttgaa gcgcgtaaag catccatgca
    50281 atctatcgct gataagatga atgaagaact tgggagcaac cgtgtcactc tcaacttgac
    50341 agaccagtac tacaatatga aagaagtcat tgaaaaagat atgactccaa ttaccattgc
    50401 taaagccgtt atggaagatc taggtatcac gcctattatc gaaccaatcc gaggtggaac
    50461 agacggctct aagatttcct ttatgggaat cccaactccg aatatctttg caggtggcga
    50521 aaatatgcac ggacgttttg aatacgttag ccttcagact atggaacgtg cagttgatac
    50581 catcattggc atcgtacgta gcttataaaa gctaaaaaga cgaggtagct cagctacttc
    50641 gcctttcttt ttattctact ggtttttctt gatttccagt agttgtagaa gattctgttg
    50701 ttttattttc tgaagttgat tcagcaggtc tagaatctct tgtattgctt ggtttgtttt
    50761 cgtcgctagc agtttcaatg ttagattctg cagttgcgtt tggttggttc tcagcactgg
    50821 tgttatcacc atttgcttca gcatttcttg ctggacttgt ttcttcactt gcgctagctt
    50881 ttgactggat ttgatgattc aaaactagaa tagcttttgt cgattcaagt aaagctgttt
    50941 tgtctttact cttagcagaa agttgatcta ataatgcatc caccttatca aagtccgcat
    51001 cagatccatt attactttct aaataagagt gaagcgacat gagaatatcg tagagttttt
    51061 gatagagtac aagtgtctga ggatcttgct cagcattttc cttttcttgt tgaagggcgc
    51121 tagcgatacg agtcaagaca tcttttacct gactgtttac ttcatccaag tctgcatcag
    51181 ccttgtttgt ggcagctttt agattttcta cttcttctgc caaggattgt ctgattcctt
    51241 cttcatggat ttgttccaag agttgatttg ccttgctcaa aagactttct acttcttcct
    51301 tgctatctgt cgcagattat tggttgctat ctaccatgta ttcctaaaac aggagagtta
    51361 taatccaaga ttacaaggcc ttacagaaat aagaaatcca gataagacaa tgtccgtcca
    51421 agacgctatt cgcttcgcac agcagcgcgg attcaatatg ctttaatttt aaagtttagg
    51481 tgtcaagacc tctttttagt gtgcccaaaa tttagagaag taatcaatca actaactttt
    51541 atttttttca aactttcagt aaactgacct aaagctaact caatctgtct ttgttcgata
    51601 ggcttgtctt tgtagatgct tctgctatca gctagaagtt gatctacttt tgccaagact
    51661 gccttctcat caaaagttcc aggtggatag ttggattgca gggatggaat cttgtttttc
    51721 aaagccgctt catatccctt agtttgaacc ttgatgtagt gattgtggtc gccatgagga
    51781 atcacaaaac cttctgaatc ttcacttata attcgattgg catcaaaacc atgaccatct
    51841 tcttcctcat ggtggacatg tagtgacgga ttacttaata cagaactaga agaacttcct
    51901 acctcttccg tgttagagtg tgatggggga ttgttaagag atgacttagg aatatagtga
    51961 tagtgatccc catgtcttac tatataagca tcacctgtat ctctgacaat atcattaggg
    52021 ttaaagacat aaccatcatc tactgcagaa acaccattat tcggtgtcac cggcaaagat
    52081 tgactgagag ctgtagtatt ccctgataat tatacttttg cgactgctaa ttcacctgcc
    52141 gacaagtcac tctcaggaat gaaatgatag tgaccaccat gtggtactat cgtagattga
    52201 aatagaatat gagcaaattg ataaggggat tttaaagtaa tttctaacaa tgatttagaa
    52261 actatgatgt gctattctaa attcaactca ctatatataa ccatcatcgg tagtataacg
    52321 tccctgtaat tttgctacag atacttctgc actagctcct ttatcgtctt taccatgttc
    52381 ttgtttttgg cgattgattt catcttttgt tcgtacattt tctgcatgag cttgatcttt
    52441 aaggtaaaca taatactttc catctccctt aataatatat cctcccttaa cctaactgac
    52501 gatatcttga tctttcggct gatagttggg ggctttcatt agtagctctt cactaaagag
    52561 cgcatcaaaa ggaactttac cattatagta gtgataatga tcgccatgag aagttacata
    52621 accttgatct gtaatcttaa taacaatttg ttttgcttga attccttctt tttgactaac
    52681 ctagtctgga gtcaaatttt cagtcttctt agtgtcttta ttactgttta catatgaaac
    52741 acgattttta tctgtattgg cctgttagct atgttggttc agagcataaa cacacagact
    52801 taaggaaagg ataacaacag atccagctgc tatatatttc tttttaaatt tcataattac
    52861 ctcatttcta taattattta tatgatgtct tcattattaa atgattaaat aaattaatta
    52921 accagttaat taattagtaa atattccacc tctttttaag ttgtatgtca agaaatttta
    52981 tatattaata ataaaatgaa attctcccaa agtcagagtt ttatttctaa cttttgagag
    53041 aacttcattt ttgattcaga ctttttctac tgctattcct tacgctatga gatcagataa
    53101 attctttttt atcacttctc cacttggcaa tcttaattca atcgttccat ccatattgaa
    53161 tataacacta tctaagccta atccgtaact agctgtaaat ttttctaatt tttcttgtac
    53221 aggatctact gctggagctt cctctaatgc tggatctaac atagggtcac tccccacatt
    53281 cccttctgga ttcaacattc cattatccgt tgagttttct ggttttacag gtttttcgtt
    53341 tggtgcctct ggtaaagaat ctgctggttt attttctgtt ggttggttct caactgttcc
    53401 agtagatact tttccatttt cagatggttt attttcacca tttccttgag gtgcttctcc
    53461 tgtaaaatct gccatattct ttttaatgac ttctcccgat ggtaaatata attcaattgt
    53521 tccgtccata ttaaacaaga cattttctag cttcatccca taactttcag caaattttgc
    53581 tactttttct tgtacaggat ccactgtagg aacttcttct aacgttgaat tactagtact
    53641 attcccagtt tcagaaagtt tttctttttc taccttctca ctagtctttg gttcttctac
    53701 cttttcatca agttttgagt tttcttgtgc tttattcctt ttaaattgtg gtagaatact
    53761 tggtttatca gtttgatttt ctttttccaa gataggtact tccacaatat aagtcgattg
    53821 attgtccaaa taagcatttg ccatgaaggt tacaggaatt ttatttccgg ccgttctggt
    53881 tgttccttgg tttaatttcg gaatcggtaa tttgatttca ccaactttat agttattttc
    53941 taaataagca tttccatgaa attcatcaaa cactctgact aaagcatcag ttcctttagg
    54001 cactgcaaat tgagggttca ctcttaaata agtatcccct gcatggaaag gatagaaaat
    54061 cgtttgactg gccattttgt aagctaaaga ggttggaact gtaaatgtac catcataact
    54121 tacttctgga taatcttttg aagcgatagt atacttaaat gtttgtcctg gtaaataagg
    54181 ctgatctaat tcaaagtttg caatattccc tactccttct ccaaatactt taccagatac
    54241 tttctccaat acttttccat ctggtgttat taattttact agcatattga tacctaattt
    54301 tttctccaat tcaggcggaa aactaaaaga aacgcgtttt tgaccattgg ctagagtaaa
    54361 gttttgatta ttaaacgtac tattttttaa caaattaaca acattcgtta attcttctcc
    54421 agtataaact ttattccctt cttttttagc aactccttct tcgggtttaa acagttcata
    54481 gttactgtga gaatgaccaa ttccaaccgg tttatgttca tcaatcggat ctgcatgatg
    54541 atgatctcca tgcggataaa taatcgcatt tttttcttta ttcacgacaa tactttcacg
    54601 tttgacacca tattgtttca taatgccagc aattttttct tcgatttttt tatctaaatc
    54661 tttcatttct ttggcattac ctggataatc ctgttcatga gatgacaaag aatctaatcc
    54721 attatgacta gttttaactt cctctaaatg tttttgcgca gctttaattt gctcttctgt
    54781 caagtccttc ttgaagaagt aatgattatg attaccgtga ctcatgataa atcctgattc
    54841 atcttcagcg ataatacgat tagcatcaaa tccgtatcca tcttcttcat gtttctcatg
    54901 tgaaattcct ggattgattg gaagagatgg agaaggtgtt gctagactat tgtttggaag
    54961 agtcggttgc ccaatttgat ttgattttgg aatataatgg aaatgatcac catgtcttac
    55021 aatataagct gtagccgttt cttcaacgat atcttttgga ttaaaaatat aaccatcaga
    55081 tgctgaagag agctccttac ttgtcgttaa agaagaagga ttgcttgaaa gactgcctag
    55141 actagacact acttcattag gttttgcatt tgtagaaact gtagaaccag ttccactgat
    55201 aggcaccatt ctggcaatct tttcttctaa ggcagaaagc ttgctgtaag gaataaagtg
    55261 gtaatggtcg ccatgcggaa tcgcaactcc atttggtgta cgactgataa tcttagcagg
    55321 gtcaaagacc aggccatctg attcactgta acgttgggcg ctaggtgaat catagagttc
    55381 cttcaaaaga ctctggagat tttcagattt atttgctggc ttgctagttg atccttttgc
    55441 tacagattgc gtgttattgt cactagctgt tgaagaatag cttaactgac tcggttgcat
    55501 attttttcca gccagatgtg ctttagctgc tgctaattca ctagcagata aatcgctttt
    55561 gggaatgtag tgatagtgac ctccatgagg aacgatataa gcattacccg tatcttcgat
    55621 aatatcagct ggattaaaga cataaccatc atttgtcgta tatcgtccct gagaccttgc
    55681 tacagcaaca ttagagttaa ccttctcatt atctttgaca tgttcttgtt tttgacgatt
    55741 gatttcatct ttagttcgaa cattatcagc atgagctgca tctttcaggt agacataata
    55801 ttttccatcg accttgatga tataaccacc cttgacttca ttgacaatat cagcgtcttt
    55861 aagttgatag tttggatcct tcatcaagag ttcttcacta aagagggcat cataaggaac
    55921 tttcccatta tagtaatgat agtggtcacc gtgtgacgtt acatagccct gatctgtaat
    55981 tttgattaca atttgctcgg cctgaattcc ttctttctgg ctaacctggt ctggtgtcaa
    56041 gttttcactt ttctgacttg actggctgcc atctacataa gagacacgat tattgtcctt
    56101 attttcctgc gaacgatgct ggtttagtgc ataggcacat agactcaagg atacgataac
    56161 agctgatcca gctgctatat attttttact gaatttcata aatccctcat ttcaataaat
    56221 gatgaagttt tttctcaact tcttttactt tattaaatag ttttctaaac cggttattta
    56281 accatttaat taaccagtaa atagtttact atttaaaatt acttttgtca agtttctgtt
    56341 acgtttttct aaaaaagaga agtaacacga aaggttactt ctccataaaa tatgctccat
    56401 tcattttact actgtatagg agtcggttga ctttctttta acaaagccaa gagactatct
    56461 acttctgctg aaatagtgtt attatctttc gttccgagaa gaagactact ttttagacca
    56521 gtcaatgtct ccacagcatt ttgtctaata ctagaatctg ttactttttc tagcaaggcc
    56581 tccgcctctg ctatcttagc gttaataaca gaatgctcta cttgaggaat ttcagcctca
    56641 tctgtagtat cttcagcttc ttcctctgtc tcttccgtat cagtgcttgg tttataaaga
    56701 ttatctgctg aaggatttaa accagcgtga ttctcttttt catcagattc agggtgagtt
    56761 ggctcactta cttcatcatg ttccttatct tcctcaggtt tttctgtctg aggtttctcc
    56821 tcgtttggtt tttccgtttg attggtatca gcttgaccat ttttgtttct ttgaacatgg
    56881 tcgctagcgt taccaaaacc attatctgaa tgcggacgtt cgtttggatg ttcgacatag
    56941 tacttgacag tcgccaaaag atcctcaaga gtatacccct taggtgcctc ataaaggcct
    57001 tcgtcaaacc actcaaattt gatgttatgg taatggtcat aatgaggtat gattaaacta
    57061 ccgtttttga cttctacagt atattgaaga ttgtaaggca tacgatcaag cggcaccttc
    57121 ttagctgctt tcacgcggtt gtagatagct tctgctcctt ttgcctcagt atttcctgaa
    57181 tcctgatggt ctgtcgaagg aggggtcaaa cctttctctt tagcataagc ctgggctgcc
    57241 gctctctcag cttcagacaa actatctttt ttaatccagt ggctatgggt catatgtgga
    57301 gttacatagg catccccctc atcactggtt atatcacgag gatcaaagat ataaccgtct
    57361 tctgttgtgt acttgcctgc caacttggct acttgaatct catcatcagt gtaggtaatt
    57421 tgcg
//
LOCUS       DBERPV010000010        57040 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.10, whole genome shotgun sequence.
ACCESSION   DBERPV010000010 DBERPV010000000
VERSION     DBERPV010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 57040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57040
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.10"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..463)
                     /locus_tag="ACL8C7_000823"
     CDS             complement(<1..463)
                     /locus_tag="ACL8C7_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395061.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCG"
     gene            complement(453..1448)
                     /locus_tag="ACL8C7_000824"
     CDS             complement(453..1448)
                     /locus_tag="ACL8C7_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395062.1"
                     /translation="MNVKKIMLIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLTKGQKVVDVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYSGAYALSHSTFLAETDENTSYVIWQRKFNQLSLPLSQHILKGKMLEIWKYRPF
                     VSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRIEEESEALENMILQYLGEDDAS"
     gene            complement(1857..2282)
                     /locus_tag="ACL8C7_000825"
     CDS             complement(1857..2282)
                     /locus_tag="ACL8C7_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395063.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVTKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEVASISLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(2411..2770)
                     /locus_tag="ACL8C7_000826"
     CDS             complement(2411..2770)
                     /locus_tag="ACL8C7_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HGS1395064.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKETVLG"
     gene            complement(2816..3022)
                     /locus_tag="ACL8C7_000827"
     CDS             complement(2816..3022)
                     /locus_tag="ACL8C7_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395065.1"
                     /translation="MDLSNKAPNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMSLGR"
     gene            complement(3009..3170)
                     /locus_tag="ACL8C7_000828"
     CDS             complement(3009..3170)
                     /locus_tag="ACL8C7_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS1395066.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(3529..4485)
                     /gene="lytA"
                     /locus_tag="ACL8C7_000829"
     CDS             complement(3529..4485)
                     /gene="lytA"
                     /locus_tag="ACL8C7_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HGS1395067.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKYDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(4861..6231)
                     /locus_tag="ACL8C7_000830"
     CDS             complement(4861..6231)
                     /locus_tag="ACL8C7_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGS1395068.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFAFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLEVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPRFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMIVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            complement(6537..7703)
                     /gene="recA"
                     /locus_tag="ACL8C7_000831"
     CDS             complement(6537..7703)
                     /gene="recA"
                     /locus_tag="ACL8C7_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HGS1395069.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEGAVNEEVTLDLGDELEIEIEE"
     gene            complement(7758..9014)
                     /locus_tag="ACL8C7_000832"
     CDS             complement(7758..9014)
                     /locus_tag="ACL8C7_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HGS1395070.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(9098..10114)
                     /locus_tag="ACL8C7_000833"
     CDS             complement(9098..10114)
                     /locus_tag="ACL8C7_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HGS1395071.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(10122..10640)
                     /locus_tag="ACL8C7_000834"
     CDS             complement(10122..10640)
                     /locus_tag="ACL8C7_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HGS1395072.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(10630..11073)
                     /gene="tsaE"
                     /locus_tag="ACL8C7_000835"
     CDS             complement(10630..11073)
                     /gene="tsaE"
                     /locus_tag="ACL8C7_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HGS1395073.1"
                     /translation="MYIKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(11159..11779)
                     /locus_tag="ACL8C7_000836"
     CDS             complement(11159..11779)
                     /locus_tag="ACL8C7_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395074.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(12162..13025)
                     /locus_tag="ACL8C7_000837"
     CDS             complement(12162..13025)
                     /locus_tag="ACL8C7_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS1395075.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            13214..13384
                     /locus_tag="ACL8C7_000838"
     CDS             13214..13384
                     /locus_tag="ACL8C7_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhrA family quorum-sensing system peptide"
                     /protein_id="HGS1395076.1"
                     /translation="MKKNRGIQKLAILVLLGVFMLSNTIPYQQFIQKNRQLEIRVQSQ
                     KKSNGLDVGKAD"
     gene            13529..15544
                     /locus_tag="ACL8C7_000839"
     CDS             13529..15544
                     /locus_tag="ACL8C7_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HGS1395077.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSYYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDSNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMNLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEVGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            15546..16178
                     /locus_tag="ACL8C7_000840"
     CDS             15546..16178
                     /locus_tag="ACL8C7_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1395078.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            16319..16597
                     /locus_tag="ACL8C7_000841"
     CDS             16319..16597
                     /locus_tag="ACL8C7_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComA"
                     /protein_id="HGS1395079.1"
                     /translation="MKKFDNYIIEKPCDSNSDKLQKILIIENLVDDILQFPLRINNSV
                     GEIFLLQPFQKKTIFIPCYFEEDIVKVKDDDKVEWNLLEFQKFRAFLA"
     gene            complement(17107..17520)
                     /gene="ndk"
                     /locus_tag="ACL8C7_000842"
     CDS             complement(17107..17520)
                     /gene="ndk"
                     /locus_tag="ACL8C7_000842"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HGS1395080.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYLPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(17631..21308)
                     /gene="rpoC"
                     /locus_tag="ACL8C7_000843"
     CDS             complement(17631..21308)
                     /gene="rpoC"
                     /locus_tag="ACL8C7_000843"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HGS1395081.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKTEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPTVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(21341..24952)
                     /gene="rpoB"
                     /locus_tag="ACL8C7_000844"
     CDS             complement(21341..24952)
                     /gene="rpoB"
                     /locus_tag="ACL8C7_000844"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGS1395082.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVIAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            25368..25438
                     /locus_tag="ACL8C7_000845"
     tRNA            25368..25438
                     /locus_tag="ACL8C7_000845"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:25400..25402,aa:Cys,seq:gca)
     gene            complement(25636..26967)
                     /locus_tag="ACL8C7_000846"
     CDS             complement(25636..26967)
                     /locus_tag="ACL8C7_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HGS1395083.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(27258..28082)
                     /gene="endA"
                     /locus_tag="ACL8C7_000847"
     CDS             complement(27258..28082)
                     /gene="endA"
                     /locus_tag="ACL8C7_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HGS1395084.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSLKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(28121..28309)
                     /locus_tag="ACL8C7_000848"
     CDS             complement(28121..28309)
                     /locus_tag="ACL8C7_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGS1395085.1"
                     /translation="MNKKSSYVINRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(28302..29585)
                     /gene="murA"
                     /locus_tag="ACL8C7_000849"
     CDS             complement(28302..29585)
                     /gene="murA"
                     /locus_tag="ACL8C7_000849"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGS1395086.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(29609..29839)
                     /locus_tag="ACL8C7_000850"
     CDS             complement(29609..29839)
                     /locus_tag="ACL8C7_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HGS1395087.1"
                     /translation="MVQLLFTLSSHMFFIYVSFYLLKDLVRWEKVLKVTDENTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(29897..30934)
                     /locus_tag="ACL8C7_000851"
     CDS             complement(29897..30934)
                     /locus_tag="ACL8C7_000851"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HGS1395088.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(30918..31406)
                     /gene="coaD"
                     /locus_tag="ACL8C7_000852"
     CDS             complement(30918..31406)
                     /gene="coaD"
                     /locus_tag="ACL8C7_000852"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HGS1395089.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDKLVVDVAKRLGATFLVRGLRNAADLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACHVPESILEEIRNEK
                     KD"
     gene            complement(31396..31935)
                     /gene="rsmD"
                     /locus_tag="ACL8C7_000853"
     CDS             complement(31396..31935)
                     /gene="rsmD"
                     /locus_tag="ACL8C7_000853"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HGS1395090.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEVGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(32000..32992)
                     /gene="asnA"
                     /locus_tag="ACL8C7_000854"
     CDS             complement(32000..32992)
                     /gene="asnA"
                     /locus_tag="ACL8C7_000854"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004071 - aspartate-ammonia ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HGS1395091.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(33104..33787)
                     /locus_tag="ACL8C7_000855"
     CDS             complement(33104..33787)
                     /locus_tag="ACL8C7_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HGS1395092.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(33843..34583)
                     /locus_tag="ACL8C7_000856"
     CDS             complement(33843..34583)
                     /locus_tag="ACL8C7_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HGS1395093.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSPALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            34617..34895
                     /locus_tag="ACL8C7_000857"
     CDS             34617..34895
                     /locus_tag="ACL8C7_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HGS1395094.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            34973..35899
                     /gene="yidC"
                     /locus_tag="ACL8C7_000858"
     CDS             34973..35899
                     /gene="yidC"
                     /locus_tag="ACL8C7_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HGS1395095.1"
                     /translation="MKSIKRFALSAMGAAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPSKASAFST
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(35974..36768)
                     /gene="pflA"
                     /locus_tag="ACL8C7_000859"
     CDS             complement(35974..36768)
                     /gene="pflA"
                     /locus_tag="ACL8C7_000859"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HGS1395096.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(36894..38144)
                     /locus_tag="ACL8C7_000860"
     CDS             complement(36894..38144)
                     /locus_tag="ACL8C7_000860"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HGS1395097.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     IWLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(38211..39038)
                     /gene="purR"
                     /locus_tag="ACL8C7_000861"
     CDS             complement(38211..39038)
                     /gene="purR"
                     /locus_tag="ACL8C7_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HGS1395098.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(39305..40246)
                     /locus_tag="ACL8C7_000862"
     CDS             complement(39305..40246)
                     /locus_tag="ACL8C7_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HGS1395099.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMSNKIFAMDNRSFYKPDLD"
     gene            complement(40236..41492)
                     /gene="rmuC"
                     /locus_tag="ACL8C7_000863"
     CDS             complement(40236..41492)
                     /gene="rmuC"
                     /locus_tag="ACL8C7_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HGS1395100.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYEVGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(41494..42156)
                     /locus_tag="ACL8C7_000864"
     CDS             complement(41494..42156)
                     /locus_tag="ACL8C7_000864"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HGS1395101.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQHFVQARPEKDDTDLELALLTIFEKNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(42119..42775)
                     /gene="rpe"
                     /locus_tag="ACL8C7_000865"
     CDS             complement(42119..42775)
                     /gene="rpe"
                     /locus_tag="ACL8C7_000865"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HGS1395102.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTSVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(42786..43664)
                     /gene="rsgA"
                     /locus_tag="ACL8C7_000866"
     CDS             complement(42786..43664)
                     /gene="rsgA"
                     /locus_tag="ACL8C7_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HGS1395103.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYRQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKLAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(43666..44538)
                     /gene="rsmA"
                     /locus_tag="ACL8C7_000867"
     CDS             complement(43666..44538)
                     /gene="rsmA"
                     /locus_tag="ACL8C7_000867"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HGS1395104.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFIHRRKTLWNNLTGYFGKTEEVKDKLTKALNQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(44789..45082)
                     /locus_tag="ACL8C7_000868"
                     /pseudo
     CDS             complement(44789..45082)
                     /locus_tag="ACL8C7_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333255.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(45075..45716)
                     /locus_tag="ACL8C7_000869"
     CDS             complement(45075..45716)
                     /locus_tag="ACL8C7_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1395105.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(45718..47748)
                     /locus_tag="ACL8C7_000870"
     CDS             complement(45718..47748)
                     /locus_tag="ACL8C7_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HGS1395106.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMTN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSVYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(47825..48121)
                     /locus_tag="ACL8C7_000871"
     CDS             complement(47825..48121)
                     /locus_tag="ACL8C7_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HGS1395107.1"
                     /translation="MKQTVKKLALVASIAATLGGSVAVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(48441..49352)
                     /locus_tag="ACL8C7_000872"
     CDS             complement(48441..49352)
                     /locus_tag="ACL8C7_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HGS1395108.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYDKEEEYDKKEACLEEI
                     EDLFYEQLPNEEKVWFEATRATIDVIRSGQPEYGETVLDDYFKTIYDKELFLINELEV
                     INLYFAIVLTKIKQGQNQIEEINRIHSFLVRLTNHVELIAPEYLFALSNTLFSGLACL
                     DNLSSYDSLGAYIFSLNHIMEKTQDFQKKPIILMLEWKLSLIINNDYVSAEQFYQKSK
                     LFADIIENSYLVTMLEKQWQEDLKKYL"
     gene            complement(49424..49984)
                     /gene="rnmV"
                     /locus_tag="ACL8C7_000873"
     CDS             complement(49424..49984)
                     /gene="rnmV"
                     /locus_tag="ACL8C7_000873"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HGS1395109.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(49984..50757)
                     /locus_tag="ACL8C7_000874"
     CDS             complement(49984..50757)
                     /locus_tag="ACL8C7_000874"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HGS1395110.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALADEMGVTQMNIVGFDKPTIE
                     RALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(51062..51802)
                     /locus_tag="ACL8C7_000875"
     CDS             complement(51062..51802)
                     /locus_tag="ACL8C7_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HGS1395111.1"
                     /translation="MCPVIILFYYKVEVAGDGTATITFPDGSVVTILGKDTVQQSAKG
                     ESVTQEATPEYKPETTPGGDKGGNTGNSDANANAGGGSQAGGPAHTGSQNSAQSQASK
                     QLATEKESAKNAIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTM
                     EDVKEAETIGVQAIAMVTVPKRPVAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSA
                     SSAALASLGLVVATSGFALLGRKTRRRK"
     gene            complement(51978..52112)
                     /gene="rpmH"
                     /locus_tag="ACL8C7_000876"
     CDS             complement(51978..52112)
                     /gene="rpmH"
                     /locus_tag="ACL8C7_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HGS1395112.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(52257..53471)
                     /locus_tag="ACL8C7_000877"
     CDS             complement(52257..53471)
                     /locus_tag="ACL8C7_000877"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGS1395113.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(53627..53920)
                     /locus_tag="ACL8C7_000878"
     CDS             complement(53627..53920)
                     /locus_tag="ACL8C7_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395114.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMIWQLESLVPLLYPGFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            54082..54534
                     /locus_tag="ACL8C7_000879"
     CDS             54082..54534
                     /locus_tag="ACL8C7_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HGS1395115.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(54569..55957)
                     /locus_tag="ACL8C7_000880"
     CDS             complement(54569..55957)
                     /locus_tag="ACL8C7_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGS1395116.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     SASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            56023..56985
                     /locus_tag="ACL8C7_000881"
     CDS             56023..56985
                     /locus_tag="ACL8C7_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HGS1395117.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLEHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
BASE COUNT        16527 a        12903 c        10592 g        17018 t
ORIGIN      
        1 aaccacaatt actcaatacc gaatacccct gaatggtttc tttttcatgc accaatatat
       61 tataataatc ttcatccaat aataaggctg ataaactagc atcttggtca aaatgtaagg
      121 gaatttctcg accgtccttc tttaatggat attctggtaa gatactaaat agttcaatca
      181 tagaaggaaa ctcaggatta gttgttgtaa atcgaaaaag ctgcgctttc tcatctttct
      241 gacttccttg atactctccc aattctaaaa aatgattcaa ggtagtataa aattccttat
      301 tttttacttc atcaatgatg accatatcat aatcttttgt tgtgcgactt ttaaatcctt
      361 gcgaatccaa tacgatagag gtagcagttc ccccaatcag aacataatag ttctgaaaat
      421 ccgcaaacat ttcttgaaaa ataactttcg tattagctgg catcatcttc tcccagatac
      481 tgtaatatca tattttctag tgcttcactc tcttcctcta tacgtgggtc atcatcatct
      541 tttaaggtca aataaagaga aatcggatct acaaattgtt tatcatgatt atttttaaaa
      601 tcattccaaa actcagatac aaaaggacga tatttccata tctctagcat ctttcctttt
      661 aaaatatgct gagaaagtgg caaggataac tgattgaatt ttctctgcca tatgacatag
      721 ctagtatttt catccgtttc agctaaaaaa gttgaatgcg acaaagcata agcaccacta
      781 tatagaaggt tagaaacaga ttttatctgc tttatatcgc catctggcaa taaaatccgt
      841 tttttgatgg gattaaataa acatgacacg gattttaaga ataattcttt ctttgacacc
      901 gtatatgtgt aaagcttatt ttgcttgttt aaccaatata aagctttaaa agtcctcaaa
      961 cacctataaa ttgttgagtt tggaagtcca gtgacttgtg aaagcaaatc aacatctact
     1021 actttttgac cttttgtcaa taaaaaggca atccacgtta attgttcgct aggtgttaat
     1081 tccttaggga cttcagtatc attcgcattc agtactagtc ccaatggagg gaagaagagg
     1141 tttcccttaa agtctacaaa cggaactcta gcttgaagta attgcttttt ttcactgtct
     1201 gataacttcg aaaacaccaa aacaacatcc atattggctt tttcacccat agtgcgagcc
     1261 tgagtaacaa atgaactcaa actccccctt ctcttttctt taatcaataa aaatgattcc
     1321 ttatgaaaag tcatttgagt atactcaaac ctttttacaa aactgattgg taaagtcaaa
     1381 gttagttcct caatactgac atcaacataa aaggattgaa aaattaacat tatctttttg
     1441 acattcatgt tttttcctta ttctatcatt tttattatat tttatcattc ggtataataa
     1501 aatataagtt ttttgataaa ataaccaaaa actactcgct atcccctctc acattaccct
     1561 acatatcgtt tgacatgcga ctgatagttc aggaaaactt caaggagaac ttttctctca
     1621 tccactatgc aggacttact atttcacttc tacatcctat aggctcaatt tgacactttt
     1681 ctttttcgaa ttgctcatat gcctcctgaa tagtgagttc gatttatcca aatttatttt
     1741 tgtctatttt gatgaatact tccacgaaga tagtctgaaa atgaatttgc accaattttc
     1801 cttctctttt taagcatatt attccagata tgattgccct cttgttcagt aataaattac
     1861 gctttaaacg cttcaatcag tatatctcct gttgtcatat gttctaaaga aaattcttct
     1921 acatatggtt taacatctct taggttatta cttcctaata tcccattatg ctttttcgct
     1981 aaggaaatag aagccacttc tcccttacca ataatcttgt tactatcatg atttcttgtt
     2041 aaatctctat ataatgcgta ttcttcagtt ccaatgtcta tgctcacaat ctcagctgaa
     2101 cccttagtta ccaactggtc tatcctagat tttaaatggg gaattgtagg tatattgatt
     2161 tcatcataca cctcttgtgg aataacaatt ttacccgaat agagcttttc taaaagatgt
     2221 tcagtgccaa cccataaaaa tactgaaata caatctgcat caataaatac acgactagtc
     2281 aaacgacaac tcccccctct tcatatagcc catatacaat atcatatctg aaagcatcta
     2341 gtaacagttc ctcatacttc ccttgcgaaa ttctgttatt ttctaaaagt tgttcagttg
     2401 aattaatata ttatcctaac accgtttcct ttttactttc tgacaaagga cgatataaac
     2461 ttgtatcata gcctaatctt gaagctgtct ctataacact aatatccata tttttaattt
     2521 cttctgcatc aaggtatcca tcattcctca atctatataa catagcttta tgactgatac
     2581 cataaaactg acccaatttt ataatatctt ctacttcaag atgagttcta ttggcatttt
     2641 ctctaatttc ctcaaccatc ctatacagtg aagatgggaa aattaaaaaa taagaagcaa
     2701 actgatccgc ttttctttca gtttcatctc cttcaccaat caagataaga ctgactgaac
     2761 tcttcttcac ctcatcataa taaagatgat acagttcatg tgctaaagaa aatctttacc
     2821 ttcctaatga catgtctgaa ttgactgcaa tgagactgaa ctgagttcct ttataacaga
     2881 ctccgctaat attctttccg agtccataaa ataccagcgt caaattttct atcttttgta
     2941 ccaatttaaa aatatctatc ggcgattcac catcagctcc caactttttt ctaagatttg
     3001 gagctttatt acttaaatcc attcgtgata ttcctttcac ctttttccat tttggcaatc
     3061 atgctttgat tcaaagacaa atactcagca atcttatctt gagtaagatt tgaagatatt
     3121 ctaagttctt ttattctttt tccaacatca catacattta tcacatacat ttatcatatt
     3181 catacacctc tcataaaaag aatagcacac tcttgtcata attttttaaa taaaaaaatt
     3241 atgacaaaac aaggaagcaa tttattgatg ctgcttaaaa atctaaaatt gatgagttcc
     3301 tatcaaaaat cgtatcttca acctcaaaac agtacttaaa gctatccgac tcggtttaca
     3361 ttgtcaaatt tagattttat ttgagcataa ctttctagtt tgctttctga tttttgttta
     3421 atatagtagc aaacattgaa ggaaatatct ccacaaaaaa acgcatacta ttaagctttt
     3481 tcaagaccta ataatatgcg ctgttctgat ttgaaagaca ttccattatt attttactgt
     3541 aatcaagcca tctggctcta ctgtgaattc tggcttgtct gccagtgttc cgtctggttt
     3601 gaggtagtac cagcctgttc cgtccgctga ctggataaag gcatttgata ccatggcgcc
     3661 ttctttagcg tctaagtagt accaagtgtc cttgtacttg acccagcctg tcttcatggc
     3721 accttcttcg ttgaaatagt accacttatc agcgattttc ttccagcctg tagccatttc
     3781 gcctgagttg tcgaaccagt accagttgcc gtctgtgtgc ttcctccagc ggtctgcaag
     3841 catatagcct gaactgtcaa agtagtacca agtgccattg attttctcaa acttgtcttt
     3901 tggataagag ccgtctgaat gtacgtacca gtagccagtg tcattcttct gccagcctgt
     3961 ttcaatcgtc aagccgttct caatatcata cttaaactgc tcacggctaa tgccccattt
     4021 tgccaagtaa gggtatggat ccacatggtc tgagtggttg tttggttggt tattcgtgca
     4081 atactcgtgc gttttaattc cagctaaact ccctgtatca agcgttttcg gcaaacctgc
     4141 ttcatctgct agattgcgta agagttcgat ataaaggcgg tagtccgtca tgaactcttc
     4201 tttagttgaa tggctttcaa tcagttcaac cgctgcatag gtctcagcat tccaaccgcc
     4261 cccaacgtcc caggcaccat tatcaacagg tcctacctgc atgatgcaac cgttcccaac
     4321 aatgtgcgag aaaaaaccta attctgggtc tttccgccag tgataatccg cttcattctg
     4381 tacggttgaa tgcggattcc cagttgagtg tgcgtgtact tgcctatatg gttgcacgcc
     4441 gacttgaggc aaatctgttc ttaatttact cacattaatt tccatattct actccttatc
     4501 aattaaaaca actcattttt tacaatccag aaccagaaac tcctttattt ctaccttaca
     4561 aagaagacaa tcttagtcac gattaggctt gtagatagaa cctcaaaacg cactattttg
     4621 acactgtaaa taggactgac aaggtctgca ttctatctac aataacaccc cagactaaaa
     4681 agcttttcaa aagtatattt ttacagtctc tatatatcct tttcataaat actatacttt
     4741 attatatcat ataaaagaag tcaaaagtct gttaaactat tttcaacacc aaactaaaga
     4801 agagaacaca agttttttcg atgttcacta gaggaaatgg attttattca gtaaatccaa
     4861 ctaggattgc actttggttg ccaaaattgc ctttccttct tttatcaagg gatgacggaa
     4921 tagtgagaag tacagttgaa ctatcatggc aacccagata agaggttcac aaaggataac
     4981 acccttatat cctgcccaag gaataatcaa aaccacaaaa acgatttttc cgattagttc
     5041 aataaagcta gaaactagag gaaggatctt ctgccccaag ccctgcaagc aattgcgata
     5101 aatcaacaag aggctcaaaa tgggataaaa ggctgaactg atttgcagat agagacttcc
     5161 attttctatc aagtaaccat ctgtcgaact agccaagaag gaaaccaagg ctggactggc
     5221 aaaaaagagg aaaatacaaa caaaaactgc ccaggatata cttaaacgac tgccgattcg
     5281 aagaccttga acaatgcggt caggtcgctt agctcctaga ttctgagaag caaaggtcgt
     5341 cattgatgca gaaatagcgg tcataggaag aagggcaaag gtcataatgc gtcgagctgc
     5401 cgtctgggca ctaataatca ctgcaccaaa tgtattaaca gaaaactgta aaatcacact
     5461 gccgatagat acaattgaac tcatcaagcc catagccaaa ccttgctcca agagatccgc
     5521 gtacaagctt ttgtcccatt tgaaatgttt aaaccgtggc aagagttctg gcacactttt
     5581 acgaatataa taaaagcaga gaaccgctga taaaccttgc gaaataatgg tagcaagtcc
     5641 tgcggattga acttccagat gcaattgcgt aataaaatag agatccagaa ccacattaac
     5701 caaggcagag aaaatcagaa atcccagggc tgctagactg tcaccaatag accgcaacaa
     5761 gcctgcaaaa agattataag caaagctgac acctacacag gtcacaatca tagaaatata
     5821 ttgataagat tgaggaagaa tttctgcagg agtatctaag tattgcaaga gaggatacaa
     5881 gccaagaaag cccagcaaca taactagaat gctcaaaaga gcacctaaaa tccaggtggc
     5941 tgctactgct tccttgattt tagtgaaatt cctagcccca taataacgag caatgacaat
     6001 ccccatgcca ttgccaacac caagtgtaaa acctacaatc aggtcaaaaa tcgctgtcgt
     6061 cgctcctact gcagccaagg attcttgacc aagaaatcgt ccaacaatca agacatcagc
     6121 agtgttatag agctgttgaa aaatatttga tagcaagatt gggaaggcga agcttaagag
     6181 cgagggaaga atcggaccat gtatcaggtc cactgttcgt tttttattca taaagctatt
     6241 atatcagctt tccagaggag cgacaagaaa cagcaaacta tatatagcgg aatgaaataa
     6301 ggacagtcaa atcgattttt aacaatgttt tagaagtaga tgtgtactat tctagtttcg
     6361 atctattata attggttgag tttggaatag tacgctgtag ctgctaaaac atttctagaa
     6421 attaatttga ctttcctaat aaagttgttc atatcttatt tcaagctact atatataatc
     6481 taaaaacttg aatcaaaaat cgaaaaagta gcggatttct ccactgcttt aacagcttat
     6541 tcttcaattt cgatttcaag ttcatcgcct aagtcaagcg taacttcttc attcactgct
     6601 ccttctttct ttggctcatc ttttttgttt tcagtatctt gttctgaaac ttcttctcca
     6661 tcaatcaagc caaatttaga acggacttgc ttatcaattt catcaaagat ttctgggtgc
     6721 tctgccaagt atttcttagc attctcagaa ccttgcccaa ttttttcatc tttgtaagaa
     6781 taccaagccc ctgctttttt gataatatcc aaatcgcttg caatcttcaa aagctcacca
     6841 gtcttagaaa ttccttctcc gtacataatt tcaactacgg cttccttaaa cggtggagct
     6901 accttatttt ttacaacctt aatcttagtt tctttaccga cattggtttc tttttggtca
     6961 ccagttccct taatttgtgt attaccacga acatccaagc ggactgaagc atagaatttc
     7021 aaagcacgtc cgcccggtgt tgtttctgga tttccaaaca tcactccaac tttttcacgc
     7081 aattggttga taaaaatggc aattgttttg gttttattga tagaggcgcc aagtttacgc
     7141 atggcctggc tcatcatacg agcctgcaaa ccaacatggc tatctccgat atctccatca
     7201 atttccgcac gaggaacaag ggcagcaact gagtcgacta cgacaagatc aactgcacct
     7261 gagtcaatca attttcccgc aatctcaaga ccttgctctc ctgagtctgg ttgagacaag
     7321 agcaattcgt caatattgac accaagggcc gcagcataag ctggatcaag ggcatgttcc
     7381 gcatcgataa aggcagcaat cccaccttct ttttgcgctt gtgcaactgc atgaagggca
     7441 accgttgtct taccagatga ctctgggcca tagatttcga tgatacgtcc cttaggataa
     7501 ccacctgagc caagggcaat gtcaagagct aaagaacctg agctcatcac ttgcaccttt
     7561 tgctccgcac gttcacccaa acgcatgatt gatcctttac caaagtcttt ctcaatcaat
     7621 ttaagagcgt cattcaaggc cttttcacgt tctgccccaa atttttttga aatttcttct
     7681 aatttttttg gttttttcgc cattctattc tcctacattc taatgatcct cagacctatc
     7741 tactattata tcaaaagtta gtcacttaat aaagccttgc gaactaggtt aaaggcatgc
     7801 ataaccgcaa tgtgacgtac atctgctcgg cttctgcctc caatattaac cttgataacc
     7861 tcagttcctt gatcttgcgc caagcctatg aagactgtcc caactgggtg tccttctagg
     7921 ctatctggtc ctgccactcc agtcaaacta attccaaaat cagactgggt cttgcttcgt
     7981 gcctgctcag ccatcttctg agctgtaaat tcagacacca caccatgttc ttccaaattc
     8041 ttggcaggaa tatccaacat ccttgatttt tcctccaagc tataggtcac aaaaccaccc
     8101 ttaaatatac ttgaaactcc agaaaaattc gccacggtag cttggaaaag acctgccgtc
     8161 aaactctctg cagccgcgat ggttttccct tgccttttca gttcttctac cacaatgctg
     8221 gctaaactag tttcttcccc ataaccatag caaaagtctc gtaaagaaat tccttcgaaa
     8281 gtctggcagt ccaagatttg attttccaag atatccagcg cttgattcgc ctcttcttga
     8341 ctgctagcct ttgttgacag acgtagagtg acttctcctg tcttggcata aggggccaag
     8401 gtaggatcga tctgattatc aattaaatca gccaaaatcg taaccagctg gctctcgcca
     8461 atcccaaaga aacgaagaac tcgggaatac agcttgctcc ctgtcatcaa cttgggtaga
     8521 agttggttta agaccatggg tttcaattca cttggcggac ctggaaggac gacataggtc
     8581 actccgtcta cttctaattt tcctccaaca gccagtcctg tttcgtttgg cagtggaatc
     8641 gctccttcta caatttgagc ttgtctttcg ttattcggtg ttcgggcata gtctggtcgc
     8701 agggcaaaaa agatatccaa cttctcctga gcctgaggat caaagactaa tgctttccct
     8761 aaaaatttag ctagggtttg tttggttagg tcgtcctcag ttggccccaa accgcctgtc
     8821 aaaatcacca gactgctacg ttgactggca atctcaagca aagacaagag acgaacttca
     8881 ttgtctccta cagccgtctg aaaatataca tctaccccaa tctcagctag tttttccgac
     8941 aaaaactggg cattggtgtt gacaatctgt cctgtcaaaa tctctgttcc aacagcaatg
     9001 atttctgctt tcatgtttcc tcctacctat ctattcgtat ttttttgaaa aaatcgcagg
     9061 aattttccta cgattgattt tttatttgta tcaaaagtta attatcttca tcaccaacag
     9121 gtgctctgcc aaataaatct tcaaataaaa ccgcattggt ttcaagctga gtaacttctt
     9181 cttgtcccaa agaacgtcgg agtatatttt gcatttccaa catatgtgct ctcgaaacaa
     9241 tctggtaaga aacaccttga agtatctctc cttcaccctg caactgctga gtttcaatgg
     9301 ttttaaatga atctttatag cctagcaagt tagggatact ttttgcagac aaatcaatat
     9361 tggtctgcat attgtcactc aaagctttta gaatctcttg ataatgacca atgctattta
     9421 aactgagagc tttttccatg actttttgaa taacttcacg ttgacgtttt tgacgaccat
     9481 aatccccctc aggatcttgg taacgcattc gtgcatagac tagggcttct tctcccccaa
     9541 tatgttgctc cccaacaccg atagaaatag tattaaattc ttcttggtca ctgatagaaa
     9601 ttgggaaacc taggatatta ttgactgtaa tacctcctac tgcatccact agtttttgca
     9661 accctctcat attgaccatc acatagcgat caatatggat attcatcatt ttttgaatgg
     9721 tttctatagc aagctctgct ccaccatctg catatgctga gttcagtttc gcttcatgag
     9781 cctgaccatt ccctgattca atgcgcgtca gaatatcccg ctctaaactc atcattgttg
     9841 tttttttcgt tttaggattc actgtcatca agatcatgct atcacttcta ccgacccaag
     9901 tttcagttcg ttcaacattt ccggtgtcca ctcccattaa cagaatggtt agaggttcag
     9961 tcgcttcaat aaccttggtt tcttcgccga tttttttata ggttttagct aaggtttctg
    10021 tcccttgttg ataaatagta taagcaaaaa cacctactcc tactacagtt acagaaagta
    10081 aagctagcac cattccaata atttttttaa ccatatttct actaacctat cagtttaccc
    10141 atcaagtaaa catcgataaa tttcccttct tctatatatg ccccacgctc ttggctacct
    10201 tcaatgacaa agccatgctt ttgataaaga tggactgctg cttgattacg agtttggaca
    10261 gtcagttgga gacgacgcag aatgccactt gcttgtgccc actctatcgc ttcttctagc
    10321 aacaaacttc ccaagccatt attccaatat ctttttccaa tcacaatgaa gagatctcca
    10381 atatgacgga ctctcttacg ctgatcagct gtaatattta caataccagc aattttgcca
    10441 tttaagaatg caagtaaggt tatctgattg tccgaactag cttgcttgtt gaggaatatt
    10501 tccatctcct cactagtcaa gagaatacca tctccgtcta ggctggtaaa gtctgtctcc
    10561 aaactcacac gatttaaaaa ggccactaat tcagctgcat ctttgggctc tgcttcccta
    10621 atgagcaatt catactccat attgaagctc ctctaacaat ttctcagcac gcaaaccctt
    10681 tgcctgaaaa tttaaacggc gtccatctgc ttcttttaga atttccaatt ctaaataagc
    10741 atctggcaag gcatctccta agagatttcc ccactcaata acagtcacgc caccaccaaa
    10801 gataaactca tccaagtcga tagaatcagc atctccttca atacgataaa catctaggtg
    10861 ataaagtgga agtcgacctt catactctct cacgatagta taggtgggac ttttaatcat
    10921 ttgagaaatc tgtaatcctt ttgcaagtcc tttagtaaag gtcgttttac ctgcacccag
    10981 ttctccagtt aagattaaaa catcattctt tgctaataga tggcccaaac gctcccctaa
    11041 ggcttgcaac tcttcttcat tttttatgta catactctta ttataccaaa aacttttctt
    11101 ttgtgtctat tttcctacta aacttatcat cataacatcc ataaaaaaca ggctttctct
    11161 aaaagaaaat gagcgtaaca atgaccaata caagatctcg gaaaatatga ccataaaagg
    11221 aaacttcctt cttaaccgaa tttgggacaa gataggctgc aaaaaacaag cccagtccaa
    11281 tataaatcag aagtgagaca atggtcattg gatttcttaa gaaaagaagt gttgctaaaa
    11341 tagtcaccaa cactgtcttt tttctgtcca gcatagcaag aaaatcgcgc acgtattttt
    11401 tcaagggtaa aaaaatcagc aaatctagcc caaataggaa aaagaaggat ggcaataaaa
    11461 agtcaactaa ttcttgctgc agcgtatttt tgatgaacaa gttatctgac aaaacaagaa
    11521 cagctcctaa caaattaatt aagagtaaca tactgtaaaa aagcttcacc gacttcttac
    11581 tggctaggac actatggact tcttgcttac gagtataaag ataatttact ccagcacaga
    11641 ttcctgaaac gaaaaccatg cttccgatga aaaaagctgt actttgttta aaggacaaga
    11701 tgcattcctt ccataggaaa cagctactca aactgatttg aattaaagct aacaaaaata
    11761 agattctcat tgatttcatc ttctctctcc cttcctacca atcattatac taggagaaaa
    11821 gagagaactg tttctaatct tctcaaatgt ctctttaaga cgctaaacaa acactagaga
    11881 ctaatactca atgaaaatca aagagcaaac taggtagcta gccacaggtt gctcaaaaca
    11941 ctgttttgag attgcagata gagctgacgt ggtttgaaga gatttacgaa gaatataaat
    12001 ttgaaatcat gaaaatccgt caaacgggtg gttgttttgt ctcgcacctc acggagcgag
    12061 acggactcag agtcacataa ttataaggct gatagtatta atctaactat cagccttaca
    12121 ggttatttaa cgtttcagaa aaactataat gtcaagatta actaaacagt atctagttcc
    12181 ttcaaataat tttctatctt catcaacatt aaaggattgt tataaatctt acataactct
    12241 cttgcttcta tataataatt tttgacttgt tctctgtcta gaaatttggc tccagcattt
    12301 cctacaagaa taagtagagg agccaattgg tagcttgtct gtctttgttt acagagttca
    12361 atcgtttcaa gagcttcttg gatggcttca ttatattttt cctttgatac taggtagtga
    12421 gcgtagttgt aacgaactct gatgtagcca aataaaaact cttgatggtc caaatttttt
    12481 gtctgataca actctattaa atgagagtag tttgcctcat attcttgttc acgacccact
    12541 aaggaataga aattagatag agtattcaac gcctttaaat aaatcagagt atttgaagag
    12601 acttttaata atatattttc caatgaagaa attgcctcac acttactgtc atattgatag
    12661 aagtcaataa tagctttaat ccattcaagg taagttcggt cttctagtgt tagaaaagta
    12721 cttcgttcaa tctctattct ataaatatat tccaaatcgt cataatttct atcgtctaat
    12781 agtcgagcag acaattgctt gaaattagag aggttagatt taatttcaat ttgttcatta
    12841 aaaaaataat ctaatggtac ttcaagtcgt tgagagagtt tgaacaaaag gtctgcggag
    12901 ggaatgaaat gccctctctc aattttacta atctgacttt gttcacaaat tccttctgca
    12961 agagtttgtt gggagagtct caactctttt cttttcaatc tgaatttctc tgcgagtgta
    13021 ttcattaaag ataataaacc ttcctatttg cttaattgca ttataaaatt tttagttcaa
    13081 aatagcaagt taaaagaata aataattctt tatggtaata aactaaaaaa agtcaaaaat
    13141 tacataaaaa tgcttgaccg aataatatat atatattaaa ataaaaacaa ggaaaaagaa
    13201 aagggtttca cgaatgaaga aaaatcgtgg aattcaaaaa ttagctatat tagtattact
    13261 aggtgttttt atgcttagta acacaattcc ttaccaacag tttattcaga agaatagaca
    13321 attggagatt cgagtccaat cacaaaagaa gtccaatggt cttgatgttg ggaaggctga
    13381 ttgatttcgt attactttaa aattcaacta tttagagaaa ggtattctga tgagagcttg
    13441 taacaatacc agatagatat tagtaagctt gttagtttat agagggcagg ggtatttctg
    13501 ccctctgttt tagaataagg aatgcactat gaaaaaatta tttatactca tatccaacct
    13561 gcttgctagt ttgttctttg tttgggtatt taccatttgg actgatacat atgtctccta
    13621 ttattacccc aacgttgttg tacatgattc ttcccctgaa acaacttttc agcatgttgc
    13681 tacacgcttg gaaaaactag cagaagaaac agatagcttt attgcgattc aacaccaaga
    13741 ttctaactca gaaggtacta cagttttttc ttatacgacc tttggggacg gaaagttgcc
    13801 tgatgggctt caggaaaaaa aactagaaga tgctcaaagt agtagtgttg aaacaaacta
    13861 ttttgtattc gatggacacc tagatattca cttgctaagg gaggagctaa gtcaacttgg
    13921 cttgactaac atgaacctga caattccatc taaactatct acgttaatgg ctatctttag
    13981 taacggattt cagttaatca gtctattgat tttcatctta acctttgtag cactgacttt
    14041 aattagtcaa attagccaat tacggtcgtc gggcattcgc ctcatttcag gagagaaacg
    14101 gtggtccatt ttccttagac cagttggtga ggatttgaaa gggatagctg ttggtttcag
    14161 tttagctggc gtgctcgcca ttcttatgca aaaaattctg tcgcttccaa cgcaatccct
    14221 aatgaccata ggagcaggct tgctcagtta taatctcatc ttgttgtcga tctccctgtt
    14281 tttcgctcaa ctcttcgcag ttgggataaa aaagatacac ctgatgcaga ttataaaagg
    14341 gcaagtgcct gtcagaggaa tcattagttt gattttaatc ggtcaactat tagcgattat
    14401 tattgtaacg ctgggaatag ggagtagctt aaagtattcc caagcctggc aacagcatcg
    14461 gattggacaa gaggcttgga gtcaggaaag gcaactgatt accctatcaa tcagccgtga
    14521 aggaacgagt cctggttttg atgaacaagc tcaaaggaaa ctcagaactt ggtatcaatt
    14581 gatggatctg gctgtttcag aacaaaaggc tttcttatct agacaccagt taattgaccg
    14641 tactttgcaa aatggcatgg cttcctccaa aaacttgata acctctacag aatggcacga
    14701 ttacaacccg aatggcaatg tccttatcgt cacaccgcaa tacttggagc gtcaaaacat
    14761 tcctgtagat acaactattg agcaaaagat gaatcacctt gatgtagggg agtttgtctt
    14821 attgctgcct gaacacctcc gttcagagga agaacattat aaatctgttt ttgaagacga
    14881 cttaaccagt cgcatgtcta gtcaagatga acgacagcaa atgactgcta cggtaggtta
    14941 tttagaatca ggtcaggatc gttttgtgta taatacgacc cctatttctt accagcagtt
    15001 tttgaaagat ccaatcatca ttgttataac accccaatca actggtccac agtccatttt
    15061 gttttggata gacgcagtac agaactacgt tctctttaat caattgtctg atgcccagga
    15121 gcttatccag agacaaggca ttgaaaattg ggtctcagaa atgcaaacag gttaccacaa
    15181 ctacatcaca ttattggata atatccagag ggaacgttgg gtaatgctag caggagctgt
    15241 gcttgggatt gcaacttcaa tcttgttgtt taacactatg aataggctct actttgaaga
    15301 atttagacgt gccattttta tcaaacgcat tgcaggtctc aggttcttag aaatccatcg
    15361 cacttatctc tttgctcaac tgggtgtgtt tttactggga tttgttgcga gtgtatttct
    15421 tcaggtagag gtaggagttg ctttcttagt cttgttactc tttactggtc tatctctttt
    15481 acagttacat gtccaaatgc agaaagaaaa caagatgtcc atgcttgttt tgaagggagg
    15541 ttaatatgat tgaacttaaa caggtgagta aatcttttgg agaacgagag ttattttcga
    15601 atctttcaat gacatttgag gctggaaaag tctatgcctt aattggttca agtggtagcg
    15661 gaaaaacaac cttgatgaac atgattggga aattagaacc ttatgatggg acgatttttt
    15721 accgaggtaa agacttggcc aattataaat cgagtgattt tttccgtcac gaattgggct
    15781 acctcttcca gaactttggc ttaattgaaa accaaagtat tgaagaaaac cttaagctag
    15841 gtctcattgg tcaaaagttg agtcggtcgg aacagcggtt gaggcagaag caggctttag
    15901 aacaggtcgg cctggcttat cttgacctag ataagcgcat ctttgagtta tcgggcggag
    15961 aatcgcaacg agttgccttg gcaaaaatta tcttaaagaa tccacccttt attctggcag
    16021 atgagccaac agcttcaata gacccagcaa cctctcagtt gattatggag attttgctat
    16081 ctcttcgaga tgataatagg ctaatcatta tcgcaacaca taatccggca atttgggaga
    16141 tggctgatga agtgttcacg atggatcatc tgaaataaaa atccttgttt ttaattgcac
    16201 gatgagttac tgaaatatta tcatgaatca agaattggag ttaatttaga attgtacttt
    16261 attaatattg aggtaacttt ttcttgataa aggaggaaat agtggagagg aagttagaat
    16321 gaaaaaattc gacaattata ttattgagaa gccttgcgat tctaattcag ataaactgca
    16381 aaaaatctta ataattgaaa atttggtaga tgatattttg caatttcctc tcagaatcaa
    16441 taatagtgta ggagagattt tcctcctaca accgtttcaa aagaaaacta tctttattcc
    16501 atgttatttt gaggaagata ttgtgaaagt caaggatgat gataaagttg agtggaattt
    16561 gttagaattt caaaaattta gagcattttt ggcttagtaa tctgtgttga aggctcaaaa
    16621 cctatggtaa aaaagtcgct ttgaaaacgt attgcctcca aagatttagt taaataatga
    16681 tttaacacaa aaagaaatta ttgaagttct ggaaagatgt tgtttcagta ttgagaaaag
    16741 gtgggaaaaa cttgcgattt tcacagagaa aggaagaaaa agtatagaaa tatagtcaat
    16801 tgaaacaaga acaggacaaa agaacctttt gtgccatatt tttctccttt cgctttacaa
    16861 ttggcttgaa cacctttatt gtatcgcgtt tggagttttt ttggtataac cttcgacgcg
    16921 cacccgcata gcgggtgttt ttttgtctcg cacctaacgg agcgagacga actaatagtc
    16981 acttaatcaa aaaaacgcac catatcaaaa actaaaaagt ttgatatcat gcgtcatgtc
    17041 ttaaactaat tgactatact ttctattcaa atgagctttt aaccaattga ttgagccaat
    17101 ccactcttaa aaccaaagag caatttctcg cttagctgac tcttctgaat ctgaaccatg
    17161 tacaacattt tggataacct cattttctcc agcagctttt gcaaagtcac ctcgaatagt
    17221 gcctggtaaa gcttcttctg gacgagttgc acccatcatg gtccgccaag tttcgattac
    17281 tttgggacca gaaatgacac ccacaagaac tggacctgaa gtcatgaatt cacgaatcgg
    17341 taggtaaaaa ctctgaccaa ccaagtcctg atagtgctgg tcaatcaact cttctgaaac
    17401 ctgtgaacga aactccaatt tttcgattgt aaatccacgt tgttcgatgc gctttaacac
    17461 ttcacccact agccctcttt ttacaccatc tggtttgatg ataaagaatg tttgttccat
    17521 acccgtctcc tttgtcagct tctttctttt attttaccac atttcgtgga aaaatggaga
    17581 aagttttcag aagagagaat gagagaaccc gagggttctc tcattctctc ttattctact
    17641 gtttcttcca cagtttcaac ggcagtatcc acaactactt ctgttgtttc ttcatttcct
    17701 tcttcctcta ctgtaggatt aaggtattct tcttcgttga cagcatgtgg ttcaaggtta
    17761 cggtaacggg ccataccagt accagctggg atgatcttac cgatgataac attttcttta
    17821 agtccaagga gatggtcttt cttaccacgg atagctgcgt cagtaaggac acgagttgtt
    17881 tcttggaagg aagctgctga caagaaactg tttgtttcaa gtgaggcttt ggtaattccc
    17941 ataaggactg ggcgacctgt cgctggaact ccacctgcga taaggacatc tttgttggca
    18001 tctgtaaagt cattgatatc catgagggta cccatgagaa gatctgtatc acctggatcc
    18061 atgacacgga ctttacggat catttgacga accattacct cgatgtgttt gtcaccgatt
    18121 tctacccctt ggctacggta aactttttgt acttcaccga gaaggtacgt ttcaactgac
    18181 aagacatcac gaactgcaag gagacgtttt ggttggatag aaccttctgt cagagcagca
    18241 ccacgcgcta cttggccccc aacttcgaca cgcatacgag ctgtaaatgg aacgacatat
    18301 tcaccttcgc cagtttcacc cttaacaaag actttcttgg tacgagttga tgcatcttct
    18361 tcgatagcag taacttgtcc tttaacctct gtgataaccg cttccccttt aggattacgg
    18421 gcttcaaaga tttcttggac acgaggaaga ccctgagtga tatcggtatt tgaggcaacc
    18481 ccacctgtgt ggaaggtacg cattgtaagc tgtgtaccag gttccccgat agattgggca
    18541 gcaattgtac caactgcttc accaacttca accgcatcac cagtcgccaa gttgataccg
    18601 taacagtgac ggcagacacc gtgacgagtg ttacatgtaa atacagaacg gatagtcact
    18661 tcttccacac cagcattgac aatttcacgc gccttgtctt ctgtaatcaa ttcatttgga
    18721 ccaataatca ctgcaccagt ttctggatgt ttaacagttt tcttagtgta acgaccgttg
    18781 agacgctctt cgagagactc gatcatctct tttccttctg cgatagaacg gatcaagaga
    18841 ccacggtcag ttccacagtc gtcctcacgg atgataacgt cttgggcaac gtcgaccaaa
    18901 cgacgagtca agtaacctga gtcggctgtc ttaagggccg tatcggtcat acctttacga
    18961 gcaccgtgag ttgagaagaa catttccaat accgacaaac cttcgcggaa gtttgaaagg
    19021 attggcaatt ccatgatacg tccattcgga gcagccatca gaccacgcat accggcaagc
    19081 tgtgagaagt ttgagatgtt accacgggct ccagagtcca tcatcataac gattgggttc
    19141 ttaggatctt ggttagcaat caagcgtttc tcaagttttt cacgggcagc acgccattca
    19201 gctgtaacag cattgtaacg ctcgtcgtct gtgatcatac cacgacggaa ttgtttggtg
    19261 atttgttcga cacgtttgtg tgattcttca atgatttcag tcttgtcatc aacgactggg
    19321 atatcggcaa tacccactgt caatcctgca agagttgagt ggtggtaacc gaggttcttc
    19381 atgcggtcaa gtagggcaga agtttctgtc gtacggaaac gtttgaagat ttcagcgatg
    19441 atatttccaa ggtttttctt cttgaatgga gggttgagct caagattgct gatagcttcc
    19501 ttgatatctc caccaagtgg caagaagtat ttagctggaa caccttctgt caagttggca
    19561 ttgtttggtt cttgcaagta tggtagcccc tctggcatga tatcgttgaa gagaatttta
    19621 ccaactgttg taagcaagac cttatgtctt tgctcttctg tccaaggctt gttgaggctg
    19681 tctgttgcga taccaacacg tgagtggagg tgaacataac cattgcggta agccataacc
    19741 gcttcgtcac ggtctttgaa gaccattcct tcaccttcgc gaccagcttc ttccatggtc
    19801 aagtagtagt tacccaaaac catgtcctga gatggagtaa ctaccggttt cccatctttc
    19861 gggttcaaga tgtgctcagc agctagcatg aggatacgag cttctgcttg tgcttcttct
    19921 gaaagtggta cgtggatggc catttggtcc ccgtcaaagt cagcattgta ggcttcacag
    19981 acaagtgggt gcaagcgaag agccttacca tcaattaaga ctggctcgaa ggcttggata
    20041 cccaaacggt gaagggtcgg tgcgcggttc aaaagcactg ggtgttcttt aatcacttct
    20101 tcaaggatat cccagatacg ctcatctccg cgttccacca agcgtttagc tgctttgacg
    20161 ttttgcacga tatcacgggc aacgatttca cgcataacaa atggtttaaa gagttcaatc
    20221 gccatttcac gtggcacacc acattggtac atcttaagag ttggaccaac ggcgataacg
    20281 gaacgtcctg agaagtcaac acgtttaccg agcaagtttt gacggaagcg tccttgttta
    20341 cctttaagca tgtggctcaa tgatttcaat ggacggctac ctggtcctgt gattggacga
    20401 ccacgacgac cattgtcaat caaagcgtca actgcttctt gaagcatacg cttctcattt
    20461 tgaacgatga tacctggtgc atttaactca agcaaacgag ccaaacggtt gttacggttg
    20521 ataacacggc ggtaaaggtc attcaagtca gatgaggcaa aacggccacc atccaactgc
    20581 aacattggac gaagatctgg tgggataacc ggaaggatgt taagaatcat ccattcaggt
    20641 ttgtttccag acttgtaaaa ggcatccaaa acatccaaac gacggatggc tttgacacgt
    20701 ttttgtccag tagctgtttt caattcttct ttgagttcag caatttcttt ttcaagatct
    20761 acttgcttca aaaggtcttg gatggcttcc gcacccatct tggcaacaaa tgaaccataa
    20821 ccatattcgc gcaagcgctc tcggtattcg cgctctgtca tgatagactt gtgctcaagt
    20881 ggtgtatcct taggatcaat caccacataa gccgcaaaat agataacttc ctcgagggca
    20941 cgagggctca tatcaagggt caagcccata cggcttggaa tccccttgaa gtaccagatg
    21001 tgagatacag gagctttcaa ttcgatatgt cccatacgct cacgacgaac tttcgtacgc
    21061 gttacttcaa ccccacagcg gtcacaaaca attcctctgt aacgaatgcg tttgtactta
    21121 ccacaagcac attcccagtc ttttgtagga ccaaagatca cttcatcaaa gagtccttca
    21181 cgttctggtt tcaaggtacg gtaattgatt gtttcaggtt ttttgacttc tccataagac
    21241 catgaacgga ctttacttgg agaagctagg gtgatttgca tacttttaaa acgatttaca
    21301 tcaaccacta tttcttccct ttctattcta agtgaactgc ttattcttgt tcagcagctt
    21361 cttctgttgc ttccgctttt gttgctttct cagcttcttc agcttcaaag gctgctttag
    21421 cctcttgggc tgctttttcg cgggcttttt caaggtcatc tacgtggatg acatcttcgt
    21481 ccattccttc atccaagtcg cgaagttcca cttcttggtc atcttcgtct aggacacgca
    21541 tgtcaagacc aagagattgc aattctttga caagaactcg gaaggattct ggaacacctg
    21601 gttttggaat tggtttgcct tttgtaatag cttcataggc tttcaaacgt ccgttgatat
    21661 cgtccgactt gtaagtcaag atttcttgaa ggacatttga cgcaccgtag gcttcaagag
    21721 cccaaacctc catctcaccg aaacgttgtc caccaaactg agctttacct ccgagtggtt
    21781 gttgggtaac agttgagtaa ggtccgactg aacgcgcgtg caatttatcg tcaaccatgt
    21841 ggtggagttt gatcatgtac atgactccaa cagaaacacg gttatcaaat ggttcacctg
    21901 tacgtccatc gtaaaggatt gtcttggcat cgctatccat acctgcttct ttaacagttg
    21961 accaaagatc ttcagaactt gctccatcaa agactggtgt cgcaatgtga ataccaagag
    22021 tacgagctgc cataccaagg tgaagctcca taacctgacc gatattcata cgtgatggca
    22081 ccccaagtgg gttcaacatg atgtcgactg gagttccgtc tggaaggtaa ggcatgtctt
    22141 ctacaggaac gatacgagag acaacccctt tgtttccgtg acgtccggcc attttatctc
    22201 cgaccttaat cttacgtttt tgagcgatgt aaacacgaac caacatgtta acacctgatt
    22261 gcaactcatc tccatttaca cgtgtaaaga tcttaacatc acgaacgaca ccatcggcac
    22321 cgtgtggtac acgaagagaa gtatcacgca cttcacgaga cttgtctcca aagatagcgt
    22381 gcaagagacg ttcttcagct gaaagatctt tctcaccctt aggtgttact ttacctacaa
    22441 gaatatcacc ttctttaacc tcagcaccaa tacggataat ccccatttcg tcaaggtctt
    22501 tgagggcatc ttcaccaacg tttggaattt cgcgagtgat ttcttcaggc ccaagctttg
    22561 tatcgcgcgt ttctgattcg tattcttcaa ggtgaacaga tgtgtagaca tcgtccttca
    22621 ccaagcgttc gctcatgata acggcatcct cgaagttgta accttcccaa gtcatgtagg
    22681 caacgattgg gttttgtcca agcgccattt ctccattttc catagaaggt ccgtcagcga
    22741 tgaaatcgcc tttttcaacg acatcaccaa cttttacgag agtgcgttgg ttgtaagcag
    22801 tacctgagtt tgaacgacgg aatttttgga tgtggtaaac atccaatgaa ccatcttcac
    22861 gacgaacttc taccttgtca gcatctgcgt aagtaacttt accatcatac tgagcaatca
    22921 cagccgcacc agaatcgtgg gctgcttggt attccatacc agtaccaacg taaggtgcct
    22981 gaggattaat caatggcaca gcctgacgtt gcatattggc tcccatgagg gcacggttgg
    23041 agtcatcgtt ttccaagaaa ggaatacatg ctgtcgcaac ggcaactacc tgttttggtg
    23101 aaacgtccat gtagtcaaca atattagctg gatactcttg gttgacccct tggtgacgtc
    23161 ccatgacaat cttctcagca aaggttccat cttcattcag acgagagtta gcctgagcta
    23221 cagtatattc atcttcttca tcagctgtca accaaacaat ttcgttcgtg acaacacctg
    23281 tttcacggtc aaccttacgg tatggtgttt gaacaaaacc atatttgttc aagtgtccgt
    23341 aagatgacaa gttattgatc aaaccgatgt taggtccttc aggtgtctcg attggacaca
    23401 tacgaccata gtgagtgtag tgcacgtcac gcacttcata tccagcacgg tcacgagtca
    23461 aaccaccagg tcctaaggct gacaaacggc gtttgtgaga caactcagaa agcgggttgt
    23521 gttggtccat gaactgtgac aactgtgatg aaccaaagaa ttctttaact gcagctgtta
    23581 caggacgaat attgataatt tgttgtggtg tcaagacttc attgtcctga acagacatac
    23641 gttcacggac attacgttcc atacgagaaa gtcccaaacg tacttggttg gcaagcaatt
    23701 caccaaccgc acggatacga cgatttccaa ggtggtcgat atcatctaca cggccaagtc
    23761 cttcagccaa gttgaggaag tagctcatct cagcaaggat atctgcagga gtcaccgtac
    23821 gaaccttgtc atctgggtta gcattaccaa tgatcgttac gacgcgatct ggatcagttg
    23881 gagcaataac cttgaatttt tgaagaacaa caggctcagt cacaacggct gcatcgtttg
    23941 ggatgtagac aatcttgttc aagtcgccat ccaaatggct ttcaatgctt tcaatcacgc
    24001 tacgagtcat aatcgtacca gcttctacca agatttctcc agtttcaggg tctaccaatg
    24061 gctctgcaat ggtttggttg agcaaacgtg ttttaacatt gagtttttta ttgattttgt
    24121 aacgaccaac tgctgccaag tcataacgac gtgggtcaaa gaagcgagct acaagcaagc
    24181 tacgtgagct ttcagccgtc ttaggctcac ctggacgaag gcgttcgtaa atttctttca
    24241 aggcttcgtc tgtacgagag tccattggat tcttgtggat atctttttca acagtgttgc
    24301 gaaccaattc gctgtctcca aagatatcaa agatttcatc atcacctgag aaaccaagag
    24361 cacgaaccaa ggttgtaaat ggaatcttac gagtacggtc gatacgagtg taggtgatat
    24421 cttttgagtc gctttcaagt tccaaccaag ctccacggtt agggataaca gttgaaccat
    24481 agcccacctt accatttttg tctactttgt cgttaaagta aacacctggt gagcggacca
    24541 actgagaaac gataatacgt tcaccaccat tgatgatgaa agtacccatt tctgtcatga
    24601 ttgggaaatc accaaagaaa acttcttggg tcttgatttc gcctgtttct ttattgatca
    24661 aacggaaggt tacaaaaatt ggtgctgagt agctagcatc gtggatacga gcttcttcta
    24721 gcgtgtattt tggttccttg atttcatatc caacaaattc caactccatt gtgtctgtga
    24781 agtttgaaat tggcaataca tcttcaaaca cttccttaag accgtggtct aggaaagctt
    24841 tgaatgagtc agtttgaatt tcaatcaaat ttggtaagtc aagaacttct ttgattcttg
    24901 aaaaactacg acgggtacga tgtttcccgt attgaacgtc atgtcctgcc aagatgattc
    24961 tcctttgtaa ataagttcca agccttgtca atcaggcttt tctaatcgtc atatggttgt
    25021 aaacccctta tcaccgtgtc ctcttgacga attttcagaa tctttaagcc tctgttacaa
    25081 atgctcataa tcttgaaaaa aagcacaaaa agagcagcta aatctgactt tttcagaaga
    25141 tttaactgct gtgagccttg tctggacaat atttcagaca aaacctacga caaatgatta
    25201 cccatattat accctattta gctagatttt tcaaggggtt tcagtaggtt tttggtaaat
    25261 tttttcccat agaaaacttg gcatcacatt cgaatcacgc tatggtacaa aaaactgaaa
    25321 aaactattga ctgaaaatca ttttcaaggt ataataataa acgttaaggc ggtatagcca
    25381 agtggtaagg cacggctctg caaaagcttg atcgtcggtt caaatccgtc taccgccttc
    25441 tataacttga tttatcaggt ttcaaatgaa cagaaagccc aatttgaagg gcttttttta
    25501 ttttccctcg aataaatacg tataacttta aaaacttttg gagcgagttt gtggcagagt
    25561 tctttccata gcataattcc cttttgaaat caattgaaaa aagcttcgtc acgcctggtg
    25621 acaaaagcct ctagtttatt ctgtttcttc ttctatttcg acttctgtga tttggacttt
    25681 taccttggta acacgtccat tcttcacttt atcattggtt aagataaact gtttgttttg
    25741 gctgaccaat tcatagctga gtttctcagt cgttggaatg gttcccactc ctgtcaaata
    25801 ataaccagcg atggtatcaa cgtcatcact ttccagctca acatcaaagt aattattgaa
    25861 atcattgagg gtcatagttc cttgaacaat gtaggtatcc tcgccaatct gatgaacatc
    25921 tattgctgct ttgtccgttt catcatcaat ttcaccaaca atttcctcta agaggtcttc
    25981 caaagtcact aaaccagcca taccaccgta ttcatccagc aagattgcca tttgtctttg
    26041 ggtatttcgc agttctttta gcaagtcatc cacaaaaata gtttcaggta caaaaagtgg
    26101 atcttgtaaa attctcttcc aaacaatatt gtcaaaaccg tccacaaagc ctgccttaag
    26161 gagactcttg gtgtgaatga ttccaattac attgtcctta tccccatcat aaaccgggat
    26221 acgagaataa ttttgtttta aaatactttg gataatggct tgactatcat cctgaatatc
    26281 caccataaag gcatccgttc gaggaaccat aacctctcgt gccatcagtt catcgagcga
    26341 aaagacacct tgtagcatct caatctcatc agcatccaat gtttcttcac tatttgtcag
    26401 catataggca atttcatcac gggtcatttt ttcatccgca tcatcgaatg acataggagt
    26461 caaatggctc aagaaattgg tcgaagcagc taaaagccaa acaaaaggac tgactagttt
    26521 tccgatccca atgataaccg gcgctgtacg aattgccaag gcatccttta gattaagagc
    26581 gattctctta ggatataatt ccccaaaaac gatggaaata taggtcaaaa atgccaagga
    26641 tagaaaagtt gccacggctt gtgctgtttc gccattccca agccaagagg caatcacacg
    26701 tcctagagta tcagttaaac tcgcccctga taagattgta atcagggtga ttcctacctg
    26761 aatggttgat aaaaagtggt taggattttc tagtaccttc agcaggcgga tgtagcgtct
    26821 gtctccttct tccgcctttt gttcaactcg ggcacgatta agagaaacca tggccatttc
    26881 tgtggctgag aaaaaggcat ttaataccgt caagataaac aataaaacaa attgtagcaa
    26941 caaattctga ctacttgggt cttccatagt tcttctccta aaatagtatc ttatccttta
    27001 ttatatcaca aaatttaatc caatacatat tatttttttc ttagcgtaac ttccatctct
    27061 ctcccaaaac tggaagttag tctaagacgg atttccactg atttcacgcg tttttctcat
    27121 actaaaagct aggttgtggg aaactggaag ttagttttag aagttactat tttttcttag
    27181 tacctattct agccctgctt aaactagtaa aaagaactcc tacatccata agtgacatag
    27241 gagtttaggc ttatctttta ctgagttaca gttacttctc cagttcggta atccagttga
    27301 agtccctttt gaacattggg aactagaaca ttgaattcca attctccatc cgaagacttg
    27361 gcttcaatct gtgaagctga gggaactaaa tcctcgtttg aagcgtagta aagggttaca
    27421 cggtaacgga cacgcttgtt ttggtccaag gctttacgca ccttgctttc atagtagttt
    27481 tgaccagtcg aatactcggc ttgtgcctga tttgcccagg ctgtctgaac agcaatgttt
    27541 ttaggattgc ttgttgaggc atcaaaacca tccaaaccac cgattaaggc atagcctaac
    27601 aaatgacctc tatcgactgc atgggtataa gagcccttta gattcttgac ctgatgccaa
    27661 cctggaggag tccaagaagt tgaaccattc ccagtttctt tacgattctt gtactgacga
    27721 gtggccttag acaagagggc attagctacg gttggaacag tttccttgcc cactgtcttt
    27781 gttttattgt cagcgtaggg cttacttgaa accttggcat ctagatttgt tttattacca
    27841 ttgacgataa aagcacctga gccattccac tccagactcc cctttatttg actcttgact
    27901 gcgtctgtta agacactctc tgccaatgct tgactaggag cttcagacgc ttgttttttc
    27961 tgactaagat tggttttgag actattaggt gccgactgca tctgcttgat ataatagctc
    28021 cctgtagaca aaagcaataa cactagcagt ccgattagtg tctgtcttgt ttttttgttc
    28081 atatttctcc ttatctttag aaaaaggctg gttctccagc ctaatttcct gtaaatttat
    28141 gaatcaattc ctgccatttt gctggagaca ggatagccca tggatcttga cccttgccca
    28201 agattccata acctaccatt agaccgattc ctagagccag agtacctaaa atcagtacta
    28261 tgatgactaa aagtaaacga ttgattacgt agcttgattt cttattcatc ttcatcgctt
    28321 gcctcaatcc gctgaatctt agcacctagc tgcgccaact tctcatggaa accgtagtaa
    28381 cctctatcca agtgaaccaa tttaccgacc acagtttctc cctgtgctac caaacctgtc
    28441 aaaatcaagg ctgcactggc acgaaggtca gttgaaagaa cttctgctcc ctgcaaaggc
    28501 tgtccaccaa caatacgagc tgtatcacgg ataatctcag aatgcaagcc catgcggcgc
    28561 atctcttcta ggtgttggaa acgattttcg aaaactgtct ccaccatggt tgattcgcct
    28621 tttgcaactg tcatcaaggc tgtaaattga gcctgcatat ctgttggaaa tcctgggtgg
    28681 ggcaaggttt tcacatgaac agcttttaga ttttctagtt gagaacgaac acgaattcct
    28741 tcgtcttctt caattacttc aacacccatt tcaagtaact tggcaatcaa gggacggttg
    28801 tgctcccaga cagcgtctcg aatcaagaca tcaccaccag tcatggcagc agctaccata
    28861 aaggttcctg cttcgatacg gtcttggact acattgtgag tcgtaccatg aagtttctca
    28921 acaccagtaa tggttatagt ctctgtacca gcacctttga ccttggctcc catttcatta
    28981 aggagaatgg ctaagtcaac aatctcaggc tcacgcgcag cattctcaat cactgtcacc
    29041 ccatcagcca gagtcgctgc catcatcaag ttctgcgttg caccaacact tggaaagtcc
    29101 atatatatat gagcaccatg caagcgttct gccttggctt cgatgtaacc agctgtctga
    29161 ctaatcttaa cccccatagc ttccagacct ttcaaatgaa gatcaatagg acggctacca
    29221 atcgtacaac cacctggcat ggataccttg gcatgaccca cacgggcaag gattggccct
    29281 aatacaacga tggaggcgcg catcttgctg acatacttgt aaggggcttc ctcagtgatg
    29341 tcgccagtag catccacctt gacaagatga gcttcctcat caaagtcaac cttggcattc
    29401 aaaccaccaa ctacctgatt cataataaag acatccgaca aaatcggaac attctgcaag
    29461 acggtctttc cttcacttgc tagaatagtc gctgccaaca agggtaagac tgcatttttt
    29521 gctccctcga tcgtcacgct tcctaccaga cgattatcgc caccttgaac cacaatttta
    29581 tccatactcg tttcctttac tcttgatttc ataataatcc tctaagcgct tcttgccaca
    29641 aatgatacag gctaataaag aaagaactca ggatgtagcc tatgacaatg ctaaaaaagg
    29701 ctactaataa acgaactttt cttgtattct catctgtcac ttttaaaacc ttctcccatc
    29761 taacaagatc ctttaaaagg taaaaactca cataaataaa gaacatatga ctacttagag
    29821 tgaataataa ttgaaccatt tgactattat accatcttct ctgtttgtgc gctagtttgg
    29881 aaacttcact caaaaattag ggattgtttt tcaagtaatc aatcgcatct tgtagggttt
    29941 taacgggcac gattttcata tccgtcttga ttgttttagc cgcttctagg gctgtttggt
    30001 agttgttttt cgcgtccgga tgcgcctttt gttcttcttc gctaacaggg ttatcaggag
    30061 caaagaaaat agcagcacct gccctagccg aagctacaac cttcttatca atacctccaa
    30121 tgtctcccac attaccatcg cggtcaatgg tacctgtacc ggcaacaata cgaccattac
    30181 gaagatctgg gtgagctatt tgagtataga tagctagact aaacatgaga ccagcacttg
    30241 gaccgccaat accagctgtt gaaaagctaa ttgggacatt gctgattacc tctgtacggt
    30301 caatcaagcc gattccaatt ccatttttgc cattttccaa ggtgataatc tttccttctg
    30361 cagacttggt ttgcccatcc tcttcatagg tgaccttgac ggaatcccct aatttttgag
    30421 aactgacgta atcaatcaag tctttggaac tatcaaaggt ctgatcattg actgctgtga
    30481 ctgtatcaga gatattgaga atccctttaa aggttgaatt atccgtcaca ttcaaaacat
    30541 aaactccaaa gtacttgagt tcgatatcct taccagctgt ttttagtcct tgatacttgg
    30601 ccatattttg cgatgtttgc atgtagaatt gattgattcg cataaattca acatcggaag
    30661 aaccacctgt agtctcctga gcactacgaa tatctgtaaa aggtgtcaac caagcataaa
    30721 tcatatgagc taaagtagca tgttgaacac caaccgtaac gaattgatag gcaccagctt
    30781 ccttatcttc tgtgtcattt actttaagga cttggcgaat atcttccgaa ccacctggaa
    30841 cctctatata gtagggcaaa ggcaccacaa atgccaagaa ggtcacaatc aaggccgcaa
    30901 tgacatacaa aggccatcta atcttttttt tcatttctta tttcctccaa aatactctcg
    30961 ggaacatggc aggcaatatc ctgaccaaac ttcaaaagct ctcgaacacc tgatgaactg
    31021 atatagagat gttcaggccg gctatgtaaa taaatagtct ctatatcaga agacagctga
    31081 tgattgtagt aatcaaaact agcttcatat tgcaaatccg ccgcattcct caacccccgt
    31141 actaggaaag tagcccccag tctttttgca acatcgacca ccaatttatc atgagaagcc
    31201 acgacttcaa cattttccaa atgtcccaaa gccttttcta gcccccgttt acgattttca
    31261 agagggagaa atccttgttt gtggggatta aaaaaaatac ccacataaag cttatcaaaa
    31321 agtctgctcg cccgttcaat gatatccaga tgcccatttg tcatcggatc aaatgagcct
    31381 gtgaataagc caatcttatc tgacatagac tgtcacctta ctaattccat aaatcttttc
    31441 cttccagata cccagacagg caatctcttc tggaagttca acggctttat ccgtctcgca
    31501 cacaaccata acatcttcag aaaaaagctc tctctcagcc attttttcaa tatctgctac
    31561 gatttgttcc ttggcatagg gagggtctaa gaaaacgagg tcaaattccc cagatacctg
    31621 ttccaatgcc ctttctgcat ccatcttgag gagttgaaat tttccaactt ccttggtcat
    31681 ctggatattt tcagccacga tggtctgagc cttacggtct cgctccacca aaacagcact
    31741 ggacatgcca cgcgatactg cttcgataga taaaccacca ctacctgcat aaaggtccaa
    31801 gactcgtccc acttcaaagt agggaccaat catgttaaaa atggctcccc taaccttatc
    31861 cgaagtaggt cttgtcgtct tgccttctag tgtcttgagg ggacgtcccc catagattcc
    31921 tgatacgatt ttcatactgt ttattatacc aaattataga caaaaagaga aagaaaaccg
    31981 aaccttgcgg ttcgattctc tacaaaatat tttcgtaagt atcgcggact tcttgaggcc
    32041 aaacacttgt ttgcacttct ccgatgtgtc tcttgcgaag taggaacatg gccatacgag
    32101 attgtccaat tcctccaccg attgtcaatg ggaatagacc attcaacaaa gacttgtgcc
    32161 attccaattc caagcggtct tcatcacctg taatttccac ctgacgtcta agagtttctt
    32221 catctacacg aattcccata gaagacaact caaaggctcc acctaaagac tcattccaga
    32281 caagaatatc accatttaga cccttgtagc cattctcaga ctcgcttgtc cagtcatcat
    32341 agtctggtgc acgtccatcg tgcggtttac catctggcaa ctcgccaccg ataccaatca
    32401 aaaagacggc tccaaattct ttacaaatcg cattttcacg ttctttcggt gtcaagtctg
    32461 ggtagcgttc taccaattct tctgtatgga taaaggtgat ttgttttggc aagatagact
    32521 cgatgtcata gcgggcttca acagctagct cagtcaggcg aatagcctta taaatcttct
    32581 caactgtttc ttttagataa acgatgttac gcttaccatt tgggataacc ttctcccagt
    32641 cccactggtc aacataaaca gagtgggttg catccaagga atcctcatct ggacgaaggg
    32701 ctttcatgtg gacaaagaga ccctctcctt caccaaagcc aaaacgagcc aaggtgtggc
    32761 gtttccattt agcaagtgag tgcaccactt cataagtagc atcagggatt tggagaacct
    32821 tgaccgatac tggattttcc acaccagaca ggttgtcctg cattccgtca ccgaccttac
    32881 tcaagatagg accttgaact tcgacaactt ctagcttatc tttcaaatac tgggtaaaag
    32941 tgtttttgac aaaggaaatt tcttcttgtt gatggataaa acttttcttc atagacaact
    33001 cctcaaaaat ttaataaacg tattatacac ctatttccaa gaaaagaaaa gagaaaattt
    33061 aaaaaaaatc agtgtcactc aaaacactga tttcatagac cttttagtca ttgcgaccaa
    33121 agatacgtag aatacttagg aaaagattga taaaatcaag atagatgctg agagccattg
    33181 acaccaccca gcctgtcgct acacgacctt gtgattgttc ataggcgagg cgaatctttt
    33241 ggttatccca agcaatcaac cctgaaaaaa ccaaaaccat ggctacgcta atcatataat
    33301 caaagaagcc actagccaag aaaatattga ctaccatagc aatcagtaaa ccaatgagag
    33361 ctgccatcat tgctcgacca atcccactca agtctttctt ggtaaagata ccaactgccg
    33421 ccatgacaaa gaagagaagg gcgctcgata caaaggcaga taaaactgta cccggagtat
    33481 agaaagccac cacaaaacta agggtaaagc cgtttaaaac ggagtaaagt aaaaatactg
    33541 gaagagcagc tggactattt cttgaagcca tgctactggc aacgaaaacc aaagccaact
    33601 ccgcaaaagt agcaatggtc aaccagagac gcccctgcat caacaagtaa accaactgag
    33661 actgaaagac cgtcaacata aggcctgata ccaaagcaga tagtccgatt cccagaccaa
    33721 caaaggcata aaccttagcg taaaattgat tgagacctgc acggtcatgt ataatagtgt
    33781 gattcatcct tttctccttt tctgtgaaca tctttccttg attataacaa aaaaagttaa
    33841 aattagctta aatggaagat taaaataccg gctgcaactg caacattcaa actctcggcc
    33901 tgccccttca tgctaatatg gaccaactgg tctgcacttt cagccataag gggactaatt
    33961 ccttgaccct catttcccat aactagtaca aaattttcta tagaaggcag ttctctgtaa
    34021 tcaacagaat ctttagatag ggttgttgct agcactggga tagctacctt tttagtttcg
    34081 tcaagaagcg ctggactagt catccggtaa atgggcagat ggaaatgact accttgcatg
    34141 gaacgtaggg ttttgagact gtagatgtct gccgacttat ctgaaacaat cactcctgta
    34201 aagcctgctg catccgcagt tcgaatgata gttcctacat taccgggatc ttgcacatct
    34261 tccaaaaaca agaacttgcc ctgactcaaa tcagcttgtc ctacttcttc tttttgaacc
    34321 accgccacaa ttccctgtgg agtctgagaa tccgccaaat ctagcaaaat atcctctgaa
    34381 atccagacag tttgcggaaa agcagctaac tgatctcgat aattttctag ggcaaagatt
    34441 ttctcaatcg tcactccagc ttggacagct tcttcaaaca agtgccagcc ttcaatcaaa
    34501 taggcagact tgcggtattt tttttggtgt aatttcttgg cattttttac cacagaattg
    34561 gcttttgagg ttataatagt catagaaata ttataacaca atcaaagggg tttggtatgc
    34621 aaaaggttag aatgattgcc caaggtaggg tacagggagt cggctttcgt tggggtgttt
    34681 acagcttggc acttgaaatt ggtggcatca caggtcgagt atggaataac gacgatggca
    34741 cagtggaaat cttagcccaa gcagactcat ctgctatcat ggcaaaattt atccaagaaa
    34801 tccgaaaagg accgacacct ttttcaaaag taagctactt agatgtcaaa ctaagcaact
    34861 ttcctcccta ctctgacttt aaaatcgcaa attaggtctc cagaactatt gtatattttg
    34921 taaaaaaaca gtagaataga aaggtataat ttttaaagaa ggaataaaaa cagtgaaatc
    34981 tattaaacgt tttgcactct cagctatggg agcggctatg ttgcttgtct tgactggttg
    35041 tgtcaatgtc gataaaacca caggtcagcc aacaggattt atttggaata ccatcggagc
    35101 ccctatggct gaagctatca agtacttcgc tactgataaa ggtctaggct ttggtgtcgc
    35161 tatcatcatc gtaaccatta tcgtgcgctt gattatcttg ccacttggta tctaccaatc
    35221 atggaaggca acgcttcact ctgaaaagat gaacgccctc aagcacgtcc ttgagccaca
    35281 ccaaacgcgt ctcaaagaag cgactactca agaagaaaaa ctcgaagccc aacaagctct
    35341 ctttgctgct caaaaagagc acggtatcag catgtttggc ggtgtaggat gtttccctat
    35401 cctccttcaa atgcctttct tctctgctat ctactttgct gcccaacata ctgaaggggt
    35461 tgctcaagca agctacctag gcattcctct aggttctcca agtatgattt tggttgcctg
    35521 tgctggtgtc ctttactatc ttcaatcgct cctttcactt cacggagtag aagatgaaat
    35581 gcaaagagaa caaatcaaga aaatgattta catgagccca ctcatgatcg tcgtcttctc
    35641 cctcttctca ccagctagtg tcacacttta ctgggttgtc ggtggtttca tgatgattct
    35701 ccagcaattt atcgtcaact atatcgttcg tccaaaactt cgcaaaaaag tccgtgaaga
    35761 actggcaaag aacccatcaa aagcaagtgc tttctcaaca ccaagtggac gaaaagacgt
    35821 tacccctgaa caaccaactg ctattacaag caagaaaaaa cacaaaaatc gcaacgctgg
    35881 aaaacaacgt tcgagataag aagaaaaagg cttagctgat ttgctaagtc tttttgcaag
    35941 tcaaaagccc gatgtttcca tcaggcttct tttctatcca tgtacacgtt tcatataatc
    36001 ttgataactt tcggtatcca tgagtttttt agcgttcttg acgcgatctg ctgttggtgg
    36061 tttgactcct tcgagggaat atggaattcc aagttcacgc cacttgaact cacccatggt
    36121 gtgataaggt agaatttcaa acttatcaac atttttgagg gtcttgacga acttaccaag
    36181 ttcaatcaag tcatcatctc tgtctgtcaa tcctggaact agcacgtggc gaatccagac
    36241 aggttttcca atatctgata gatactgggc acaagccaag atatttttat tggtttggct
    36301 agtgacaatc ttgtgctgtt cttcgttgat ttccttgata tccaaaagaa ccaagtcagt
    36361 gacagccatg agtttgtcaa acttctcaag gtaacgcggt ttattacgga aaggaagagc
    36421 acaggtgtcc aaggtacagt ggattccttg ttccttagcc ttggtgaaga gagcaatcag
    36481 gaaatcaatc tgcaagagag cttctcctcc actgactgta atcccaccct tatttcccca
    36541 gaaaccacgg tagcgcaagg cctctgtcaa gacatcatct accgtccgtt cacgtgactt
    36601 attggactcc atagcccaag tgtctgggtt gtggcaatac tggcaacgca tgtgacagcc
    36661 ctgcaaaaag acaataaagc gaataccagg cccatctact gacccaaagc tttctgtcga
    36721 atgcaccatc cctgtcactt gtccataatc aattgtttct tcagacatat cgttaccttc
    36781 cttgaaaacg ttttatagtt ttattatatc acgacttgaa ggaaaaacaa gatttttgcc
    36841 tattttttag aaagcaatct gtttttcaat ttcattttca atctatcatc agattattct
    36901 tcaaaatcaa agccatataa ggttgcaaaa tagtcctcgg ggcgctctgc acggcggatt
    36961 tgacgggctt taccttcttc ggtatagagg atttccgcag aacgtaattt ggcattatac
    37021 tggtagccca ttgaaaatcc gtgggcacct gtatcatgaa ttaccagcaa atcaccgatt
    37081 tctgtatgag gcagttcgcg attgactgca aatttatcat tgttttcaca gagtgaacca
    37141 accacatcta ccgcttcagc tggtccatct ggatgggtca cgttgctaat atgatggtaa
    37201 gctccgtaca tagctggacg catgaggttg actgctgagg catccacacc tagataggta
    37261 cggtaggttt ccttcttatg agtgactctt gtgactagag caccgtgagg tgccagcata
    37321 aaacgaccca attcggtgaa aatcttgacc tgaccaagac ctgctgacgt aagaacttct
    37381 tcatacacct tacgaactcc ctcaccaatc aaggcgatat cgttcggctc ctggtctgga
    37441 cgataattaa caccaatacc gccagaaaga ttgataaagt ctagccaaat gcccaacttt
    37501 tccttgattt caacagccag ttcaaagagc tgacgagcca actctggata atagagatgg
    37561 gtcacggtat tggacgctag gaaggagtga atcccaaaag tcttggctcc tttttccttc
    37621 aagatagcaa aggcttcaaa gagctggtcc ttggtcatgc caaacttagc ctccccagga
    37681 ttgtccataa tgtctgtccc cagttcaaaa acgcctccag gattataacg acaagagatg
    37741 atttctggaa tgcctgctac tctctccaga tgttcaatat cttcaaaggc atccaagtta
    37801 atggtcgcac ccaattcacg tgcataggcg tattccttgt ctggcgtgtt gttggaagag
    37861 aacataatct cagaacccag aaagtccagt ttatggctca tcaaaagctc tacataacta
    37921 gagcagtcca caccacaacc ttcttcttgg agaattttca aaatagctgg agttggagta
    37981 gccttaactg caaaatattc cttaaagccc ttgttccacg aaaaagcttg gttgacggct
    38041 cttgccttct cacgaatccc cttctcatca tacaagtgaa agggagtcgg gaactcggca
    38101 acaatcgctt ctaactcttc tctattgata aatggtgttt tcataagctt ccttctattc
    38161 tgtttgcaaa gaaaggctgg gacaatcgtt ccaaccttta gttctatctc ttatttatct
    38221 tcgtcaaaga tattgccaac ctcaacatcg atggcttggt tcttgacatc aatattggtt
    38281 accttcaaga gtgacttgta gtcaaactgc ttttcacgtt cttcttgggc attgtccgca
    38341 aagaccgcta cacctgccag ttctgagtcg aactcgcgca agagactaat cataccattg
    38401 accgttccgc cacctttcaa gaagtcatcc acaatcaaga cacggctgcc tgccttaaga
    38461 ctacgttttg aaaggaacat tttctcgata cggtcaccac ttgaacctga aacatagttg
    38521 acgctaacag ttgaaccttc ggtaattttc aggtcacggc gcacaatgac aaaagagaca
    38581 ttgaggacat tggcaactgc atttgcaagt ggcacaccct tagttgctac ggtcataacc
    38641 gcgtcaattt tttggtccat aaagcttttg gcaataatac gaccaatatt tttcaagatg
    38701 gctggtgtgc taagcaaatc agacagatag atataaccac ctggcaagat acggtcactt
    38761 tctgacaact tggtacgcaa gtcttcaacc atttccttag catcctgact cgagatagac
    38821 ggtgtgaaga tgacacctcc gccagcccca gtcactgtct ggatatgacc gatttcaatt
    38881 tcctcaaagg cgcgtttgat aatgacgata tcttctgaga tggatgattt agcagactca
    38941 tacttttcag caaaagtatt gagactagtt agtttataag gattattaat caaatagttg
    39001 gaaatgacaa ccatccgatc acttcttctt aatttcattt ctatttccta ttccattttt
    39061 attcaaaaaa tcaaaaagca aactagaaag ctggtcgctg gtggttcaaa acactgcttt
    39121 gagattgtcg atagaactga caaaccctgt aatatacctg catatataca tacgacaagg
    39181 cgatactacc ctagtttgaa gagattttcg aagagtattc atttttgtct tttacttatt
    39241 ataccatatt cacataaaaa aacgaacatt cttatcctaa aaaatgctca tttttcttaa
    39301 attattaatc taaatctggt ttatagaagg aacgattatc catagcgaag attttattgg
    39361 acatctctcc tttatccacc aaagccagag ctgttgacat catcatcatg cttgcatcca
    39421 gattgtcaat catatggata atctctgcct ccataatacg tggacggact ggacttccat
    39481 attcaagcaa gccgtggtga ctgaggatga catgacgaag caaaacgact tcttccttgg
    39541 tatcatcgat gccgagttcc ataactgtct tggtaatttc gctatcaatg agagcgatat
    39601 gtccaagaag attgcctctg accgtgtact cggtctggtc tggtcccgtc aactcgatga
    39661 ccttagccaa gtcgtgcaac ataatccccg catagagcag actcttattg agctgaggat
    39721 aaacttcgct aatagcgtct gccaaacgta ccatggtcgc cgtatgataa gccaaccccg
    39781 tttcaaaggc atggtggttg gtcttggcag ctggatagga gtagaattcc ttatcatact
    39841 tggtgtagag atttcggaca atccgttgcc agacaggatt ttcaattttg aaaatcattt
    39901 gcgacatgta gtcacgaatt tccttgacat caactggtga cttgaccttg aaatcggctg
    39961 ggtcattggg ttcaccagct tgaggcaggc ggagagtaat ttgattgact tgaggggtat
    40021 tgttataaac ttctcggcgt cctttcatgt ggacaacctt acctgcggta aaggcctcaa
    40081 tgttatgagg ttgggcatcc cagagcttcc catcaatctc gccactatca tcttggaagg
    40141 taaaggctag gtagtttttc ccagctcgag tttgcctcag gtcagctgat ttgattaggt
    40201 aaaagccttc aaatagctca tcttttttca tgtgactaat cttcatattc ttcctcattt
    40261 tcttgaaaat ggagtagatc aagcgcaggc tcgccttctg acaactcaat gtgacggagc
    40321 gtccgctcga tagctatggt acgacggttt aataattcat caatattgcc agaggcatgt
    40381 tggagatgtt tttgtgcctt gaccagaata ccaccaaact tgccaaactc ggtcttgaca
    40441 ctggcaagag tcttgctgat atggtcggca ctcttttgga tattaagggt cttgaaacca
    40501 actgataggg agttaagaag ggctgatagg gtacttggtc ctgcaacaat aatctgttct
    40561 tcccgtctca aatcatcaaa gaagaccgga ttgcggacga tttctgagta gagaccttct
    40621 gtcggaacaa acaaaactcc aaaattggtc gtccgaggtg gtgctatgta cttgttccta
    40681 atatccctag caaaacgctt gacacttgct aggagtgact tacgacagcg ttcgatttca
    40741 tccttgtcac ctacttcata ggcttcttcc aagcggtaat aatctgccag tggaaactta
    40801 gagtcaattg gtaggtagac gtattcttgg tcgccttgtc cgggtaactt gatggcatac
    40861 tccactcgtt cactagagtt ttcaaccgtt gcgtattctc gttcgtactg ggcaggtgtc
    40921 atgatgtctt caataatttg ccccagttgc aattctccca gaatccctcg cgtcttggtt
    40981 ccagagagaa ccttgttaag agctccgaca tcacgggcaa ctgtctgcat ttctccaaga
    41041 ccacgattga cagactccag ttgtttagaa actgtctcaa aggaagcctg taagcgtgtc
    41101 tgcaaggtct tttctagttt ttcctcgacc gtctggcgca tttgttccaa acgttgctca
    41161 tttgattcct gcaaggcttg gagacgttgg tctgtcttgt ctctagtttg gaggagatta
    41221 tctgtcattt cttgacggac ttgggtcagg ccttggtgca attcaatccg cacttcttgc
    41281 aaacggtcgc tgacagccac ttccaaatct ttttggtcta actggctggc ttgtctggct
    41341 tggtcaaagc ggtaatccaa ctggtctgac aaatgatctg cctgatcctc caagctctta
    41401 cttaagtgtt tctcctgcct atcctgcctt tgccaaatca gaaagagacc agctaggttg
    41461 gcaattaata atagaataag taaactttcc atcctacctc ctatccttgc tatgcagtac
    41521 gaccacataa ccatctgggc aagttaccga cacttcccta tctatatatt cgttagaagc
    41581 gtacactttt ttaaagaaaa aattttcctc tgtcaactca tacttggctc caagaatagt
    41641 cagctggcta tcccgaactg gcataaaggc tagatagtcg tagtctgaac gaggttctag
    41701 ctgactggtc ccttctggac aataagtaat caagttttgc ccatcctcaa tttctatttg
    41761 atgcatatag ggtgccaact taggattgct aggcagaaag acattggcca acatatggtc
    41821 aatacggcca cccaaggcac cgaaaatagt aacctgagcc tgaggatttt tctcaaagat
    41881 ggttaagaga gccaattcca aatcggtatc atctttttct ggtcgggctt ggacaaaatg
    41941 ctgggcacgt ttttgaatca cctgtcgctc ttcttcggtc acagaatcaa aatccccaac
    42001 tgctagagca agaggcaagt cttcttccaa gacccagagc gagcctcgat ccaccccaac
    42061 aaaagcatca aaatctgtcc gataatgacc gcggtctccg cctgcaaaaa cggcaaccct
    42121 agtccagttg ttttctgaga gtttgtactc gctcattgac atctccctta aagacatagg
    42181 aacctgctac aaaaacggtc gcaccagctt ctttggcttg agcaatagtt tggtcatcaa
    42241 tcccaccatc cacttcgatt tcaaagttca aacctttttc ctcacgaaga gcaaccaact
    42301 cacgaacctt atccatggtt tctggcagaa aggcttgccc accaaaacct ggattaaccg
    42361 tcatgactaa aacttggtca actagatgaa ggacgtgctt gatggcttca actgatgtgc
    42421 caggattgat aacgactgaa ggcttaactc cgagtgaacg aattttttgg agggcgccat
    42481 gaatatgagg cgttgcttct acatggatac tgatgatgtc tgcacctgca cgcgcaaaat
    42541 cttccagatg atgctcaggg tttgacacca tcaagtggca atcgaaaacc atcttactat
    42601 gaggacgaag gctctcgacc acacctgcac caaaactgat ttgcggtaca aaatgactgt
    42661 ccatgatatc gatatgggca tattctgccc cagttgcttc tagacgtttg atttcacgtt
    42721 caaagttggc ataatctgct gccagaattg acggagcaat cttgtattga gacataggtt
    42781 tctccttatt ttggaatttt tttgctgact tttttatagg tttctctacg attttcaatt
    42841 tcactaagga attgcaggta attatcaaaa cggaaggttg caataacacc ctcttcaaca
    42901 gctggtttga cggcacaaga cggctcatgg gtatgggtac aagtacggaa cttacaatct
    42961 cggctaacag tagcaatctc tgggaaagcc tgattgaggt cttcagccct tgatacttca
    43021 tagtccaagg atgaaaatcc tggtgtatct gcgattttac ccccgttgag attgtaaaaa
    43081 ctaacagctc gagtggtatg gcgaccgcga cctagactgt ctgaaatttc tcccgtttca
    43141 agattgaggt ctggtgcgag tttattgaga agagttgact tcccaacacc tgtctgcccc
    43201 ataaagaccg taaccttgcc tgttaacaaa gacaggagtt cctctttact ggtcacaaag
    43261 tcatagccga tgtcaccata ggtctgccgg taaaaatcca gttctcccct atcttccaac
    43321 aaatccattt tggaaatata gacaatggga tggatgccct tgtgctccaa aagaaccaag
    43381 aaacgatcca gcaaattgct gttaaaatca ggttccttga cggacatgat tactacagct
    43441 tgatcgatat tgacaatagg cggacgaacc agactgtttt tccgttcgtg aatttttagg
    43501 atatagcctt ctgaattttc ctcggcagag aaatctaccc agtccccaac ataaggggta
    43561 tggccttttt tacggaaatt cccacgcgcg cgtgtttgat aaacctggcc atcactctcc
    43621 acatagtaga aacctgccaa ggctttaatg atttgtccct gcatcttaga gtccttgccc
    43681 tttaagtgcg tctgctagac cggcaaattc tgccaagctg agagcttccc cacgcacact
    43741 tggtgacaag cctgcctggt tcaaagcctt ggtcagcttg tccttgacct cttcagtctt
    43801 accaaagtaa cctgtcaagt tattccacaa ggtcttacgg cgatggataa aactagcctt
    43861 ggaaacctta aagaagaagt tctcatcttc cactgctaca gctggctctg gacggcgcac
    43921 cattttcaag atggctgaat ccacatttgg cgctggcaca aagaccgtac gaggcacgat
    43981 aaaggcaacc ttggctgtca tgtaatactg cacggcgata gacaagctac cgtaagcctt
    44041 ggtgttaggc tgggctgaaa tgcggtccgc tacttctttc tgcatcatga ccacaaactc
    44101 actaaaagga atgccactct caatcaagtg catgagaata ggcgtcgtga tgtagtaagg
    44161 caaattagcc actaccttga ttggcaggtt aggattttta aaattttgga tatgttgcgc
    44221 caaatcaacc ttgagaatat cttcgttaac tacggtcaca ttatcaaaat cacgcagagt
    44281 atctgccaaa attggcacca aacggtggtc aatctcaaaa gccatgactt gggctgcacg
    44341 ctcagccaaa aattctgtca aggcaccaat acctggcccg atttcgatga cattgacctg
    44401 atcatcaatt tcagccgtat ccacaatttt ttgaaggata ttggtatccg tcaagaaatt
    44461 ttgcccaaag gactttttaa aggtaaaacc gtgacgctcc aacactgcct tggtcacgct
    44521 ataatctgca attctcatct attctctttt ctattatctg ttactactat tgtaacacat
    44581 tccccttgta ttttgggaat gaaaatcata ccaaaaaact atctttcctc atgaagaaag
    44641 atagtcttgg aaatctttaa agagggactt agcgcttctc tcgaaacata cgttcatact
    44701 cttcgaaaat ctcttcaaac cacgtcagct tcaccttgcc gtactcaagt acagcctgcg
    44761 gctagcttcc tagtttgctc tttgattttc attgagtatc aaaaaaatca gcttcttgat
    44821 aacttcgatt ttcgggtagg gtcaaatcca catcctcctc cacatcatcc actgtcagtt
    44881 caaccgtttg aggtaaattt ttcaaacgat aatgcttttg cctttaccct tcaatactag
    44941 caaaatcaag caaatagcca tgcactcgga tttgaaccaa aaggagatga ttggtcatat
    45001 tttccatgat gaggatatct tctaaaccac ctctgacact aggataatca gataccctgc
    45061 gaatacggat tttttcacac atgagcaagt ttcctcatat caatgatttc atcagcctta
    45121 ttccagacta ggggattatg ggtcgcaatg atgataattc gattttcatc tttcaaatcc
    45181 accaagagat tcataacctc ctctgaattt tcaggatcaa gagctgctgt tggttcatct
    45241 gccaaaatca agggtggatt tttcaaaata gtcttagcaa gggcaactcg ttgggcctct
    45301 cctccagata aagtatagat tttttgttct aaatccaaat accctagatt aactttttct
    45361 aaagccccca cttgcctttc caaacgttct acttttgaga ttttctgacc aacaaaaccc
    45421 aaatccaaat tttctttgat tgattggttt tctaagaggc cgaaattttg aaagagatag
    45481 cccatctggt ctcgaaaata ctcacgagtg ggaatggttt ttaaatcttt cccctgatag
    45541 agaacccttc caccatctat cttttctagc tttcccaaga tattcagcag cgtcgtcttt
    45601 ccgcttccac tctttccgat taaggcataa accttgccct tctccagctt gagattcaaa
    45661 ccagagaaaa tcgcgcggtc attaaatttc ttttccaatc cttgaatatc aatcatctta
    45721 ttttcctttc aatactgcca tgctaccagc ttcttctttt ttgtcctgcc ttactaaaat
    45781 caagagggcg ttaagcgtaa acaaagctac aactagagcg ctaatcaaac catctcttgt
    45841 caaaatacta gataggacta ggccaagcaa gagaactcct ccttgcgcca gtaaatactt
    45901 gccatgaagc tcatagattg tcataccagc aagacgttta atcataagct cccgtctgaa
    45961 ctgctcaaaa tagagaagat tcatggaatc aaataacaag atagccgtag acagggtcaa
    46021 aatcgtccca ataaggagag agtaaaactc cacccgtttg tcatttagta ccttggcaaa
    46081 aaatagctgg ctttttacca agtaagaaac cttgtgatac agaccttgct cttttagagc
    46141 tgtgatgctg tctccatatc gatctagttt caaggcacta ttagccgtag ttccccacaa
    46201 catccctgca acaggtcttg ttccagtcgc ttgcggcgtt agaactacaa taatcggatc
    46261 ttttaggtac tggcgtgttg tcttgtaccc atcattatag aggaaacgtt cctgtcctgt
    46321 ttctgtaaaa gctagcctta cctgtgggag gtagtgtttc tgactcgtca cttctacact
    46381 ttcagatgaa aagttttgca ggtaatctgt aaacaatcct tggtagtaga cagactgctc
    46441 tcgcaagctc tcaggcaaga tcagcccaaa ctctccctca gacaagtttt gcatcttgtc
    46501 cataaactct gaagaaacgg taatcttttc ttctatcaga tagcgtggtg agacatagat
    46561 aacattccct gacggtgtgt agtcactgag acgattgcca tctaggtcca cttctgctcc
    46621 atctgagaaa ttgtcaacat tgctcataat ataaaaagag tctgtattgg ctaaccgttc
    46681 ttcagtaaat gtctgccact cacgattatc cttacgcgtt ccttcttcat cggcaaatgc
    46741 actagaccaa ccaaaggata gacggtaacg gtctgaggac tggctccatt tattgctagc
    46801 tctctccatt tcctgcattt cacggtagtg gggtaggaga gctgtcgcac tcgatccgac
    46861 caccaataca gctaagagtt gccccaccat catcaatgtc atcatacgtt tgagagggag
    46921 tttccctttc aatagatcca ccagactatt ttcctgtaaa ccaagtagat agacgacact
    46981 tagtaaggta gaaatccctg ccaaggtcaa tccataaagt agaagagcaa tgatgaccag
    47041 ttgcaccgtt gccataaaca aggcaccttg ataccagaga atccccaatc ccaaaagact
    47101 ggataccagc actgagcaga taagctgtct cacatcttct aacactggtc tgagagcaac
    47161 tccaaacaag ctctcaccag ctattaagcg aatccctgcc tgacgaaggg atttgatccg
    47221 ataaatcagg gtcagactca taaaggtcag cagaaaaata gctaaactca gtagcaccat
    47281 aggggtggcc gtcaatagta agactatcga aaatggatct tctccattcg aaacaaagcc
    47341 ttgataacca agctctttca aggtggtctg taagctcact ccatccaaac ttcctgatac
    47401 aatcaagtaa gaccctaata aatcactcgt ttctgcactc tccttggagg aaatggtcag
    47461 accttctgga agctttccct caccataagt ggcataggta aagcgtgttt ctccagcttc
    47521 atttggctca acgattcgac gagcaatgag actattgtgc tctaccgcca agtgactcaa
    47581 agcctctgtc acctcttcgc gactagctac tggttgattt gtcatcattc ctgtcacatc
    47641 aacagaagga tagttaccaa ataaaatctc ttctcgatgg tcaacggaag ttatcaccat
    47701 ataaagcgat actaatacca ttgaaatcaa aataaataaa cgtttcatca tttcctccaa
    47761 aaagttactt ggtcacttag tgagaaggtg accaagtaaa gctaaacaat agggctatac
    47821 cattctaaac attatagtag aatgcaactt tctctcccca agaagtacga atccatgcac
    47881 gagaagtccc tccagcacca gcatatccct tgtcagatga accagttttt ctgctaacaa
    47941 ctgttgaact atggtatttt gaagggtgat agtagtttga gtaagcacca ccgttacctg
    48001 aaccataagt ccaaacacca ccttctgggt attgaacggc tgcagaggca actgctacac
    48061 ttccacctaa tgttgctgca atgctcgcta caagagctaa ttttttaact gtttgtttca
    48121 tattgatact cctctatttt tgattacaag attgttgagt tacttgctcc tctttccatt
    48181 atcaacgttg atactattat attaccaaat gatattctaa aattatttgt ttttctctaa
    48241 attgtcaaaa tagcaccctg aaatgaactt ttatagtcat tatactccat ctttatcaca
    48301 ctatcaagga catcaatgtc cttaaaatct aactatttca tattattttt agcttatatc
    48361 taaaaaaaca gttctaaaga cgaactttag aactgttttg atacgaggac aaggacattt
    48421 ttgtcactga ttcactatgt ttataaatat ttttttaaat cttcttgcca ttgtttttct
    48481 aacatagtaa ctaaataaga attttctatt atatcagcaa atagcttcga tttctgatag
    48541 aactgttcgg cagaaacata atcattgttt attattagag ataatttcca ctccaacatt
    48601 aatataattg gtttcttctg gaaatcttgt gttttttcca ttatatgatt aaggctaaag
    48661 atataagctc ctagtgaatc ataagacgac aaattatcca aacaggctag acccgaaaac
    48721 aaagtgttac ttaaagcaaa cagatattct ggtgcaatta attctacatg atttgtcaaa
    48781 cgaactaaaa acgaatgaat tctgttaatt tcttcaatct gattttgacc ttgttttatc
    48841 tttgtaagca ctatagcaaa atataagttg ataacttcta attcatttat caaaaacaat
    48901 tccttatcat aaattgtttt aaaataatcg tccagtacgg tttccccgta ttctggttgt
    48961 ccgcttcgaa taacatctat cgttgctcta gtagcttcaa accatacttt ctcctcatta
    49021 ggaagttgct cataaaataa atcctctatc tcttccaaac acgcttcttt cttatcatac
    49081 tcctcttctt tatcatagat tggttcacgt aaaatctggt atttcaattc taaataagca
    49141 gaaggaagag ctgaaaaatc cggcataagg ctataaactg gaactcctag ccggcgagca
    49201 atatagtcta acttgggcaa actcggttgc gaagctccac tttcaattcg cgacagttga
    49261 cgaactgtca gttcttgctc atctccacaa aaatctggac gactaattcc tttttctatc
    49321 cgaatctctt taattttttg accaattaac atcagacgcc tcctcttcta cctgcttcga
    49381 aaaatactgt gaaacttaaa aaattgtaac ggctacatct ttcctactca taagatttca
    49441 tagcttcttc cacttctgcc aaagtaaccc caaacaactc taggcgtttg aggagttgct
    49501 tgccgttaga atagccgatt cggagagtct ctccgagata ttctctacgc ttacggctgt
    49561 ctgcccctgc tagaaaacca aggcgaatca aatcgctacg actaatgtca aactgactct
    49621 catgttcaaa ttgttctgtc acctgagcta gagccgtttt caggtcttca tagctggcat
    49681 gctcaattcc cagagaacgc cccttggtct tggacttggg aacagcttca tctcgcttga
    49741 gaaaggcatg ctgaactgtt ggaatggccg tcataatcat gcgccgaatc cgctccccat
    49801 taaaatctgg gtctgtaaag acaatgactc catgacgttg gtgtagacgc tgaattcgct
    49861 ctatatcctg atcattgatg gcagaacctc gtgtctcata ggtctccaca tcgaaataac
    49921 gcttgagatt gaccgtatca tcgcgacctt caaccacgat aacttgagaa attttctctt
    49981 tcattacttg ctgtccaatc caaaaattcg ttctgcattt gcagtcgttg ctaccgccag
    50041 ctcttctgtc gtcataccac gcaagtcagc gataaagtcg accacatagc gagtataggc
    50101 tgttttattt tcacgaccac gcttgggtac aggtgctaag taaggcgcat ctgtttccac
    50161 caacatcttg tccaaaggta actctttagc tgcttcttgg aggtcagttg ccttcttgaa
    50221 agtcaccact cctgagaagg aaatggtcat accaagatcc acaaacttct ctgcccactc
    50281 aagcgtccct gaaaatgaat gcatgatacc accacgagga ccaacgccct cactcttgat
    50341 aatctcatag gtatcttcca gcgcatcacg ggtatggaca acaaaaggca aatccaagtc
    50401 cttagatagc tgaatctgac ggcgaaaaac ctgctcctgc acctctttgg gcgctgtcat
    50461 ccaatggtag tctaagccaa tttcacctaa agccacaacc ttgggatgtt ttaacttatc
    50521 caacaagtaa gcctcaactt cctctgtata agtaccagct tctgtaggat gccaaccaat
    50581 agtcgcatag agctgctcat actcatctac caactccaag gcacgctcaa tcgtcggttt
    50641 atcaaaacca acaatattca tctgtgtcac acccatctca tcagccaagg caatttcttc
    50701 tgcctcacga cctgcaaatt cttctacatt caagtgtgta tgtgtatcaa aaatcatctc
    50761 ttctaacctc gttttctatc ttctattata ccaaaaaaga ggaggggcac ctaatttttc
    50821 ggtttcccct cctctcttca atagagagct attctgctat cttttctatc cgatattgcc
    50881 catctcctat tccacagtta gagacagaag agattggcta cattgataga atattcctat
    50941 tcagctaaag tatgtgatta tcttgggttc tcacttttct cacccatcac taggattgat
    51001 gacttctcaa aatccccctt ataatctaac tttaagtaga gaatagaatt ttctagctgt
    51061 tctattttct acgtctagtc tttcttccta gcaaagcaaa accacttgtt gccaccacta
    51121 gaccaagact agcaagtgct gcacttgatg ctgaacctgt gttaggtaat tgtttgccag
    51181 caggtgactg gtaggtaaca tcttgcattg ttcctgcagt tgcttgcggt gcacttgttg
    51241 tcttaggagc cactggtctc ttaggaactg taaccatggc aatggcttgc actccaatcg
    51301 tttctgcttc cttcacatct tccatagttt tcgcattttc aatctctttg agagctgctt
    51361 gtttttctgc ttccactctt gctaaaagtt ctgctttttc tttatcagaa agcggtgcgc
    51421 ctttgatttc atcctgcttg tccttggctg ctttttcaat ggcattttta gctgattctt
    51481 tttcagtagc taattgctta gaagcttgtg attgagctga gttttgtgaa cctgtgtgag
    51541 ctggtccacc tgcctggcta ccaccgcctg cattcgcatt agcatctgag tttccagtat
    51601 tgcctccctt atctccacct ggtgtagttt ctggcttata ctctggtgta gcttcttgag
    51661 ttacagattc acctttcgca gattgttgaa ctgtatcttt tcctagaatc gtcactactg
    51721 aaccatctgg gaatgtgatt gttgctgtgc catctccagc tacttcaact ttatagtaaa
    51781 ataaaataat aacaggacaa atcgatcagg acagtcaaat cgatttctaa caatgtttta
    51841 gaaacagagg tgtactattc tagtttcaat ctactataac atcgcttccg aatccatttg
    51901 catctactga acttttttac aaaaataaaa atcagtagac tcgagttcct actgattttt
    51961 gatagaattc gtttggatta tgcagccaaa actttgcgtc ctttacgacg acgagctgcc
    52021 aatacgcgac gaccattttt agttgacata cggttacgga atccgtgttt gcgcgcacga
    52081 cgaagtttac ttggttgata agtacgtttc acgatgaata cctcctcata gattttgtat
    52141 tcgtttagcc ggctataaag tgatcagtta ctaaacatac tttactattc tatctgattc
    52201 tttcactttt gtcaatagct ctaggcaaat gtttccagct ttttcgaatg caagccctat
    52261 ctacgatact gtttcaagaa acgagtcatc ttttcttgga tttgggctaa ctcatcaaca
    52321 cgaggaaggt aaacgatacg gaagtggtct ggttcctgcc agttaaagcc tcgaccatga
    52381 accaagagaa ccttttcctg cttcaagaaa tcaaggacaa actgctcatc atcatcgata
    52441 cggtacatat tgcggtcgat ttttgggaag atatagagcc ccgccttggg tttaacggca
    52501 gacaaacctg gaatatcttg aatggcatta tagatgaaat ttctttgctc gtagattcgt
    52561 ccaccaggaa gaagcaattc atcgactgat tggtgacccc ccaaggaagt ttgtacgact
    52621 tgttgggcca aaacgttaga gcaaaggcgc atattggaca gcatattgag cccttcgata
    52681 tagcccttaa catgagtctt agggccagac aagaccatcc aacccacacg gaaacctgct
    52741 atgcggtggg attttgacag accattcatg ctgacacaga agacatctgg tgccaagctc
    52801 gccacaggcg tatgcacatg tccgtccatt accatgcggt catagatttc atccgcaaag
    52861 ataatcaaat cgttttgacg ggcaatctca ataatctcca gcaagagttc cttaggataa
    52921 agggctccag ttgggttatt tggattgata aggacaattg ccttggtatt ggaagtgatt
    52981 tttgacttga tatcgtcaat atctgggtac cattccacag cttcatcaca gatatagtga
    53041 acggcatttc ctccagctag gctgacagcc gccgtccata gaggatagtc tggcattggc
    53101 actaagacct catccccatt gtccaaaagc ccctgcatgg acatgacaat caactcactg
    53161 acaccatttc caaggtaaat atcatcaata tctacgtttg ggaatttctt cagctggcaa
    53221 tactgcatga tggccttacg ggctgagaaa atccctttgg agtcagaata gccttcacta
    53281 tcacgtgcat tcataatcaa gtcatgaatg acctcgtctg gcgctgtaaa gccaaattct
    53341 gctggatttc ctgtattcag acgtaaaatc ttttctccat tcgctcgcat ccgcatggct
    53401 tcttccaata caggaccacg gatatcataa gcaacatgct ctaacttact agacttatta
    53461 tattctttca tcttgtttcc tcaattcatc aggatagtaa cattatacca ctagaaagag
    53521 aatgcgacaa gtttactgaa atgtgttact agtttcgtat agaaaaaaaa ccttgctaaa
    53581 agcgaggtta agaacgtaga gatagcaggt attttgcaaa gacacatcac ataccaaaag
    53641 ataaacctag aaaaagcaag cctagaaagg agtcataaag aagattaaac atgaggaaaa
    53701 gcccccatat catcaagtaa tcccaacgcc cacttcgttt tgcaactaga aataagatta
    53761 gatggtagag tacatgaaag actaaaaatc caataaaacc tggataaaga agcggtacca
    53821 gactctctaa ttgccagatc atgatcactt ctaccaagac tgaaactagg ataattccat
    53881 aatacaggaa atttgatttt tgaaaagagt ttttcatcat tctcccttcc ttcacttctt
    53941 tcctgctatc ctttctttta ttttatcata tatttatata gattttaagc cctaatattc
    54001 ttttgaaaaa tacttttttt gctttacttc tatagtgaaa aggtttacaa ttatagtaag
    54061 aaaattgcag gaggtttcat tatggcacaa cgttaccaaa atatcatggt cgcaatcgat
    54121 ggttctaagg aagcggactt ggcttttgtc aagggagttc attctgctct acgaaacgac
    54181 gctaaactca ccatcgcaca tgtcattgac acacgcgctc tccaaagcgt atccaccttt
    54241 gatgctgaag tttacgaaga actccaagtc gacgctgaaa gtctgatgaa agagtacgaa
    54301 aaacgtgcta aagatgctgg ggtagcagat gttcatatcg tcattgaaat gggaaatcca
    54361 aagaccctgc tagcacgtac tattccagat gccgaggaag tggacctcat cctcgttggc
    54421 gcaactggtc tcaacgcctt tgaacgcctc ttggtcggct cttcatctga atacatactc
    54481 cgccatgcta aggtcgattt gctggttgtg agagaacaag aaaaaacctt ataatcacaa
    54541 agaaaaggag cccctagctc ctttttgttt acgatttatt tctctcttta tggcgttcgt
    54601 aagccttgag ctggcgctgc agttcctttt taatagcagg ttctggagca tatttttctt
    54661 cccaattatc tggttttaag attttatggg tcactggatc aaaatgagcc ttaccatctg
    54721 gaaaaatttt ccccatattg gcctgatgga caatatcaaa aatacgttct gggtccaccc
    54781 ccatcaagac aaaactgccg taggtgaagt aaagcgtgtc aatcaaggca tccacttgcc
    54841 ctatcaaatc ttgctgagca ggtgtcttct tggctacttt acctgctgcc ttatcaaggg
    54901 cctgatgaag ttgcgataca gcttgaccaa aatcttcttc agaaggactg gctgatcgaa
    54961 caaactccac caattcttct attttaaaac cagccctatg ggttgcaccc tctaaatccc
    55021 aagctcgagg ttcttcttgg gttcgttcat ccatcatgtg gtggaaggtc ttgaccttat
    55081 tgaaatgata gtcacggctg acaaagactt tttctgaaga caaaacacca aaatgttcca
    55141 aggccttgtg gatcccatct tgttgattgc tagtggtaat gtgcttggca gcttccttga
    55201 cactgctact accatttccc atagcgaccg acataccgac gccagccagc atttcaaggt
    55261 cattatctga gtcaccaaaa gccatgactt ggttgaggtc aaagccatat tctttcccaa
    55321 ctcggcgaat gccttctaat ttagaatttc cctgattgat gacatccgat gcaaaaggat
    55381 tgctacgtgt caatttcaag tcttcaaaat cagctgccgc cttctcagat tcttctggtg
    55441 tcatcagcat caaaacttgg tagataggct gattcatcag gtgaagcagg tcctcttcct
    55501 tttggggaac aaccttgctg accatgcgat taaaagactg actcaccgtc cgagttaaaa
    55561 cagagggaac gaagcgacta attcgttggg aaaaagaacc cagaccaaag gacatgattt
    55621 tagaacccaa catggcatcc ttggtcccta gagcaatctc cgtgccctct tttttagcat
    55681 agctaattag atggcgcaaa tgtaacttgg aaatagggct cgtgaacaag actctgtctt
    55741 tactaaagat atactggcca ttataggtta ccgcaaaatc cagatccaaa tcgtccatca
    55801 attccttaac aaaaaaaggt cctcgccctg tcgctacgcc aactagtacc ccttgttctt
    55861 tgacaatctt aatcgcgtcc ttagtggatt tcaaaacact cttgcgattg ttgaccaagg
    55921 ttccatcgat atcaaaaaaa acagctttga cttccatcct attccaatct ccccttttgt
    55981 gatacaatga ttataccaca tttcagaaag agttagtaaa tcatgcctaa gaaaatcctt
    56041 gttttacata cgggtggaac tatttccatg caggccgatg cttctggcgc tgttgtgacg
    56101 agttcagata atcccatgaa ccatgtgtcc aacccacttg aaggaatcca agtccacgcc
    56161 ttggactttt ttaaccttcc aagtccccat atcaaaccca aacatatgct ggtcctctac
    56221 cagaaaatta aagaggaagc agataactac gatggagtgg tgatcacaca cggaaccgat
    56281 actttagagg aaacagccta tttccttgat accatggaag ttccccatat gcctatcgtt
    56341 ctaacaggag ccatgcgtag ctccaatgag ctcggtagtg atggtgttta taattaccta
    56401 agtgctttac gagtggccag cgatgacagg gctgctgaca aaggagtttt ggtcgttatg
    56461 aacgatgaaa tccacgctgc caagtatgtc accaaaacac atacgactaa tgtcagcacc
    56521 ttccagactc caacacatgg ccccctcggt ctcatcatga aacaggaaat cctctacttc
    56581 aaaacagctg aacctcgtgt tcgctttgac cttgaacaca tacaaggttt agtccctatc
    56641 atctcggctt atgctggtat gacagatgag ctgattgata tgctggattt agaacacttg
    56701 gacggtttga ttatccaagc cttcggagct ggtaatattc ccaaagaaac ggctcaaaaa
    56761 ttagaaagcc ttctgcaaaa aggaatccca gtcgctctgg tatcacgatg ctttaacggt
    56821 attgccgagc ctgtttatgc ctaccagggt gggggcgtac agttgcaaaa agcaggcgtt
    56881 ttctttgtta aagaactcaa cgcccaaaaa gcccgcttga aactcctcat cgccctcaat
    56941 gccggactaa caggacaggc tttgaaagac tatatggaag gctaatactc ttcgaaaatc
    57001 tctgcaaacc acgtcacgtc gccttaccgt atgtatggtt
//
LOCUS       DBERPV010000011        51865 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.11, whole genome shotgun sequence.
ACCESSION   DBERPV010000011 DBERPV010000000
VERSION     DBERPV010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 51865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51865
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.11"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(240..602)
                     /locus_tag="ACL8C7_000882"
     CDS             complement(240..602)
                     /locus_tag="ACL8C7_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HGS1395118.1"
                     /translation="MLEVGLNSLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYPYLRSIVSTVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
     gene            complement(1504..2193)
                     /gene="rplA"
                     /locus_tag="ACL8C7_000883"
     CDS             complement(1504..2193)
                     /gene="rplA"
                     /locus_tag="ACL8C7_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HGS1395119.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVTLAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(2401..2826)
                     /gene="rplK"
                     /locus_tag="ACL8C7_000884"
     CDS             complement(2401..2826)
                     /gene="rplK"
                     /locus_tag="ACL8C7_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HGS1395120.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            complement(3135..3851)
                     /gene="ldcB"
                     /locus_tag="ACL8C7_000885"
     CDS             complement(3135..3851)
                     /gene="ldcB"
                     /locus_tag="ACL8C7_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase LdcB/DacB"
                     /protein_id="HGS1395121.1"
                     /translation="MKKRYLVVTALLALSLAACSQEKAKNEDGTAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(3854..4324)
                     /locus_tag="ACL8C7_000886"
     CDS             complement(3854..4324)
                     /locus_tag="ACL8C7_000886"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGS1395122.1"
                     /translation="MCLICQRIELIKKGENPYFVKELETGYLVIGDHQYFAGYSLFLA
                     KEHVTELHHLEKETRLRFLEEMSLVQEAVAKAFTAEKMNIELLGNGDAHLHWHLFPRR
                     TGDMNGHGLKGRGPVWWVPFEEMTAETCQAKPDEIKRLVKRLSSEVDKLLEIKE"
     gene            complement(4326..5363)
                     /locus_tag="ACL8C7_000887"
     CDS             complement(4326..5363)
                     /locus_tag="ACL8C7_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HGS1395123.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDGQQTDEYTVSICVKDASGPYHYDFRQHLVTLA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYIKSALVD"
     gene            complement(5461..6786)
                     /gene="brnQ"
                     /locus_tag="ACL8C7_000888"
     CDS             complement(5461..6786)
                     /gene="brnQ"
                     /locus_tag="ACL8C7_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HGS1395124.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(6957..7244)
                     /locus_tag="ACL8C7_000889"
                     /pseudo
     CDS             complement(6957..7244)
                     /locus_tag="ACL8C7_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658232.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(7404..7583)
                     /locus_tag="ACL8C7_000890"
                     /pseudo
     CDS             complement(7404..7583)
                     /locus_tag="ACL8C7_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520460.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
     gene            complement(7702..9102)
                     /gene="pepV"
                     /locus_tag="ACL8C7_000891"
     CDS             complement(7702..9102)
                     /gene="pepV"
                     /locus_tag="ACL8C7_000891"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HGS1395125.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNIYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(9115..9720)
                     /locus_tag="ACL8C7_000892"
     CDS             complement(9115..9720)
                     /locus_tag="ACL8C7_000892"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HGS1395126.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            9891..10691
                     /locus_tag="ACL8C7_000893"
     CDS             9891..10691
                     /locus_tag="ACL8C7_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS1395127.1"
                     /translation="MKKLSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(10873..11706)
                     /locus_tag="ACL8C7_000894"
     CDS             complement(10873..11706)
                     /locus_tag="ACL8C7_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGS1395128.1"
                     /translation="MNHKIAILSDVHSNATALEAVIADAKNQGASEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEVLDGEYGLEYPKEIQSMRMTQFLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINTGSIGMPYFNWEALKNHRAQYAVIEVEDGELLNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDF
                     L"
     gene            complement(11696..13540)
                     /gene="uvrC"
                     /locus_tag="ACL8C7_000895"
     CDS             complement(11696..13540)
                     /gene="uvrC"
                     /locus_tag="ACL8C7_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HGS1395129.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVAAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(13579..14280)
                     /locus_tag="ACL8C7_000896"
     CDS             complement(13579..14280)
                     /locus_tag="ACL8C7_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M57 family metalloprotease"
                     /protein_id="HGS1395130.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(14359..15591)
                     /gene="murN"
                     /locus_tag="ACL8C7_000897"
     CDS             complement(14359..15591)
                     /gene="murN"
                     /locus_tag="ACL8C7_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HGS1395131.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(15596..16816)
                     /gene="murM"
                     /locus_tag="ACL8C7_000898"
     CDS             complement(15596..16816)
                     /gene="murM"
                     /locus_tag="ACL8C7_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HGS1395132.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRVV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(16928..17707)
                     /locus_tag="ACL8C7_000899"
     CDS             complement(16928..17707)
                     /locus_tag="ACL8C7_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGS1395133.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(17776..19437)
                     /locus_tag="ACL8C7_000900"
     CDS             complement(17776..19437)
                     /locus_tag="ACL8C7_000900"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGS1395134.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(19612..21834)
                     /gene="recJ"
                     /locus_tag="ACL8C7_000901"
     CDS             complement(19612..21834)
                     /gene="recJ"
                     /locus_tag="ACL8C7_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HGS1395135.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQNQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            22111..22869
                     /locus_tag="ACL8C7_000902"
     CDS             22111..22869
                     /locus_tag="ACL8C7_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS1395136.1"
                     /translation="MALVEFKNVEKYYGDYHAFRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLETVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKAVLENVT
                     LAPIEVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            22880..23674
                     /locus_tag="ACL8C7_000903"
     CDS             22880..23674
                     /locus_tag="ACL8C7_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HGS1395137.1"
                     /translation="MKKKFFLSALLISLFGLAAAKPVQANTSIADIQKRGELVVGVKQ
                     DVPNFGYKDPKTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRDPLLDNEQVDMDIA
                     TFTITDERKKLYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQSSITQRLITE
                     LGKKKGLTFKFVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTALLDDSFKPSD
                     YGIVTKKSNTELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            23687..24364
                     /locus_tag="ACL8C7_000904"
     CDS             23687..24364
                     /locus_tag="ACL8C7_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS1395138.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAVGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHTIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQSFTYISAMRLITLPQAFRIILPPLTNQIVN
                     LIKNTSTVAIVSGVDLMFVTKSWSALNGNYIPGFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            24374..25033
                     /locus_tag="ACL8C7_000905"
     CDS             24374..25033
                     /locus_tag="ACL8C7_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS1395139.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVRNVPNLLWIFTIFLVFKIKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            25291..26481
                     /locus_tag="ACL8C7_000906"
     CDS             25291..26481
                     /locus_tag="ACL8C7_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HGS1395140.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHSLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKTSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(26802..27683)
                     /locus_tag="ACL8C7_000907"
     CDS             complement(26802..27683)
                     /locus_tag="ACL8C7_000907"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HGS1395141.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(27824..29152)
                     /gene="vncS"
                     /locus_tag="ACL8C7_000908"
     CDS             complement(27824..29152)
                     /gene="vncS"
                     /locus_tag="ACL8C7_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HGS1395142.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGATMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(29149..29805)
                     /gene="vncR"
                     /locus_tag="ACL8C7_000909"
     CDS             complement(29149..29805)
                     /gene="vncR"
                     /locus_tag="ACL8C7_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HGS1395143.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASIAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(29854..29937)
                     /gene="pep27"
                     /locus_tag="ACL8C7_000910"
     CDS             complement(29854..29937)
                     /gene="pep27"
                     /locus_tag="ACL8C7_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HGS1395144.1"
                     /translation="MRKEFHNVLSSGQLLTDKRPARDYNRK"
     gene            complement(30117..31496)
                     /gene="vex3"
                     /locus_tag="ACL8C7_000911"
     CDS             complement(30117..31496)
                     /gene="vex3"
                     /locus_tag="ACL8C7_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HGS1395145.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(31548..32195)
                     /gene="vex2"
                     /locus_tag="ACL8C7_000912"
     CDS             complement(31548..32195)
                     /gene="vex2"
                     /locus_tag="ACL8C7_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HGS1395146.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKDTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(32208..33485)
                     /locus_tag="ACL8C7_000913"
     CDS             complement(32208..33485)
                     /locus_tag="ACL8C7_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1395147.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
     gene            complement(33842..34012)
                     /locus_tag="ACL8C7_000914"
                     /pseudo
     CDS             complement(33842..34012)
                     /locus_tag="ACL8C7_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron maturase-specific
                     domain-containing protein"
     gene            complement(34155..34754)
                     /locus_tag="ACL8C7_000915"
     CDS             complement(34155..34754)
                     /locus_tag="ACL8C7_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395148.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNSSLYTTIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEVTVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNHP
                     AGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVTKYAR"
     gene            complement(34891..35775)
                     /locus_tag="ACL8C7_000916"
     CDS             complement(34891..35775)
                     /locus_tag="ACL8C7_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS1395149.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGSQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(35779..36165)
                     /locus_tag="ACL8C7_000917"
     CDS             complement(35779..36165)
                     /locus_tag="ACL8C7_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HGS1395150.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            complement(36158..37501)
                     /gene="cysS"
                     /locus_tag="ACL8C7_000918"
     CDS             complement(36158..37501)
                     /gene="cysS"
                     /locus_tag="ACL8C7_000918"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HGS1395151.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVAA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKDFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            complement(37583..38467)
                     /locus_tag="ACL8C7_000919"
     CDS             complement(37583..38467)
                     /locus_tag="ACL8C7_000919"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1395152.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGKLVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEILLADSLY
                     QDQISQLKFQAFSEGHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            complement(38479..39096)
                     /gene="cysE"
                     /locus_tag="ACL8C7_000920"
     CDS             complement(38479..39096)
                     /gene="cysE"
                     /locus_tag="ACL8C7_000920"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HGS1395153.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KYDFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            complement(39112..41325)
                     /gene="pnp"
                     /locus_tag="ACL8C7_000921"
     CDS             complement(39112..41325)
                     /gene="pnp"
                     /locus_tag="ACL8C7_000921"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HGS1395154.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRLELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEAYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            complement(42012..42878)
                     /gene="metF"
                     /locus_tag="ACL8C7_000922"
     CDS             complement(42012..42878)
                     /gene="metF"
                     /locus_tag="ACL8C7_000922"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HGS1395155.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNSISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            complement(42942..45191)
                     /gene="metE"
                     /locus_tag="ACL8C7_000923"
     CDS             complement(42942..45191)
                     /gene="metE"
                     /locus_tag="ACL8C7_000923"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HGS1395156.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLDTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSFVAAYQEVFAKLADLGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLFQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYAGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            complement(45452..45718)
                     /locus_tag="ACL8C7_000924"
     CDS             complement(45452..45718)
                     /locus_tag="ACL8C7_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS1395157.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAVVRLEQGKS"
     gene            complement(45802..46290)
                     /locus_tag="ACL8C7_000925"
                     /pseudo
     CDS             complement(45802..46290)
                     /locus_tag="ACL8C7_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            46446..47447
                     /locus_tag="ACL8C7_000926"
     CDS             46446..47447
                     /locus_tag="ACL8C7_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGS1395158.1"
                     /translation="MIKTFLSALSVILFSIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFLFFFLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            complement(47515..49920)
                     /gene="pheT"
                     /locus_tag="ACL8C7_000927"
     CDS             complement(47515..49920)
                     /gene="pheT"
                     /locus_tag="ACL8C7_000927"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HGS1395159.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVESVESPAADLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEEARQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPENAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNESAADALSVSIGTDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDN
                     FEGTDIRVREARDGEKLVTLDGEERDLAETDLVITVADKPVALAGVMGGQATEISEKS
                     SRVILEAAIFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASMIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVTQKLRRQVRTIAE
                     GVGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNFALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLQVTYTATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEAALQPATPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(49997..50506)
                     /locus_tag="ACL8C7_000928"
     CDS             complement(49997..50506)
                     /locus_tag="ACL8C7_000928"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1395160.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            complement(50506..51552)
                     /gene="pheS"
                     /locus_tag="ACL8C7_000929"
     CDS             complement(50506..51552)
                     /gene="pheS"
                     /locus_tag="ACL8C7_000929"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HGS1395161.1"
                     /translation="MSTIEEQLKALREETLTSLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
BASE COUNT        14651 a        11812 c         9774 g        15628 t
ORIGIN      
        1 attcagtcta ctatacataa actaacctcc tcattattag caaggcttct actgattata
       61 acctaattct tagactactt caagactaac tgtccaataa taatctacag ataaatcatc
      121 cactcttaat caaattttat tcaatccatc tactcattcc caaaaggttg ctgtataatg
      181 caagacattt ttcttactgc ttttactttt ccttaccctc aatttagtga gctaataaat
      241 tattcttctt caaaaggttg agatttatct agtaactcta aaacattaat ggtaggtagc
      301 aacattgctt cactgctatc aattgccgaa actgttgaaa caatagaacg taaataagga
      361 taaagaatag cagtaccatt tacgtataga atatcggtga tattttcatc tatatttatt
      421 tcaaaatatc ctattacagt tacagatatt tttttcatgg catctttgtc aactaaagaa
      481 acactaagtt ttacggctcc atgactataa tcatctgtat gaccaacctt aactatggga
      541 tataatatat cgaaggtaaa tgtgaacaaa ctgattaggg aatttaaacc aacttctaac
      601 aatgtgttat actcaatgaa aaccaaagag caaactagga aactagccgc aggttgctca
      661 aaacactgtt ttgaggttgt agatggaact gacgtagtca gctcaaaaca ctgttttgag
      721 gttgtggata gaactgacga agtcagtaac catacgcacg gcaaggcgac gttgacgtgg
      781 tttgaagaga ttttcgaaga gtattagaaa gctcgatgga ctattccaga ttcattccac
      841 tagatttcga aatcgagtag gggataatct ctagcccctc tcacaccacc gtacgtgccg
      901 ttcggcatac ggcggttcaa ctaactgtta acgcatgtcg ttcaaggtaa taatccaaac
      961 acgaaaccag tccacgtttt tcaaggactg gttttgatat agcacgttta agtaccgact
     1021 tctgagctac tatagtagat tgaaactaga atagtacatc tcttcttcta aaacattgtt
     1081 agaaatcgat ttggctgccc tgatcgattc gtcctactct tatttcattt tactataatt
     1141 gatagtggtc gccccagcca gataccttat ccgctatata ggccttatta tcatgttcct
     1201 gttcgtagag ccacgatttc gctatccctt cctctgacga ttcttatttc ctgcgtcaga
     1261 cttgggaatc gctattgggt tcaccggtag caggtgccca ccgaggactt acacctcaaa
     1321 tatataataa aatgaaataa gagtaggacg aatcgatcag gacagtcaaa tcaatttcta
     1381 acaatgtttt agaagaagag atgtactatt ctagtttcaa tctactatac aacatgcccg
     1441 tcgtacatca aaaaaagttg agacatagcg tcttcaactt ttttacatta ctttaactac
     1501 tgattaaagt gagtttacgt caactttgat accaacacct tgagtagttg tgatagtcaa
     1561 gtttgttacg taagttcctt tagctgtagc tggttttgct ttttggattg tttcgttgaa
     1621 agctttaaag ttttcaacca atttttcagc ttcaaatgat actttaccga tgattgcttg
     1681 aacgttacct gcacggtcag cacggtaagt gattttacca cctttagact cttcaactgc
     1741 tttagcaaca tccattgtta cagtaccagt tttagggttt ggcatcaagt tacgtggtcc
     1801 aaggacacgt ccaagacgtc caacaagagc catcatatca ggtgtagcga taactacgtc
     1861 gaagtccaac caaccgtcgt tgattttagc aacaaggtca tcttcaccaa caaagtctgc
     1921 accagcagct tttgcttctt cagcttttgc accacgtgcg aaaacaagaa cacgtgaagt
     1981 tttaccagta ccgtttggca ataccattgc tccacggatt tgttggtcag cttttttaac
     2041 gtcgatgttc aagttgtaag caacttctac agttgcatca aattttgcaa agttagtttc
     2101 ttttgcaagt gttacagctt cttctacact gtatgctttt gtgctgtcga ttttctcaag
     2161 agcagcacga agttgtttgc tttttttagc cattttctat tctccttgta agtggttcaa
     2221 tcgattttca tctcccacgt cacttctcga aatgatgaag tcttgcgggt tttcagtcta
     2281 ctatttttct cttcctacgg ccttaagctc ccttgctgta cccaagtaca agcctcagtc
     2341 acttgcctag tatgaaaagc aactaataga ctgctgtgag attttctact gtgttattga
     2401 ttagtcaaca acagtgaatc ccatagaacg agcagtacct tcgatcatac gcattgcaga
     2461 ctctacgttt gctgcgttca aatctggcat cttagtttct gcaatttctt gtacttgtgc
     2521 acgagtaact gtagcaactt tagttttatt aggtgtacct gatccttttt caacacctgc
     2581 agcttttttc aaaagaacag cagctggtgg tgttttcgta acgaaagtaa atgatttatc
     2641 ttcgtaaact gagataacaa ctggaatgat cataccagct tggtcagctg tacgagcgtt
     2701 gaactctttt gtgaatccca tgatgttgat accagcttga ccaagagcag gtccaaccgg
     2761 tggagctggt gtagctttac cagcagggat ttgcaatttt acaagttttt cgactttttt
     2821 agccattttt aaatcctcct ttgtggtttt ggcggtaatt agagattttt acctcccaca
     2881 agtatgtttt tcacataccc atccattata cactatttat ctggaattgc aagagaaaag
     2941 tttatttttt atactcaatg aaaatcaaag agcaaactag gaagctagcc gcaggctgct
     3001 caaaatacag ctttgaggtt gcagataaaa ctgacgaagt cagctcaaaa cactgttttg
     3061 aggttgtgaa tagaaccgac gcagtcagta ggtaaggcga cgctgacgtg gtctgaagag
     3121 attttcgaag agtattaatc gacgtagtct ccgccttcaa agccatagta ttcttccaaa
     3181 ctgagaccgc ttgcagcaat ttctttagct tcttttccta cataacgcag gtgccattcc
     3241 tcagccatat agcctgtttc cttttccttg cctttgagat aacggacaac aaagccataa
     3301 tcagctgcat ggtccaagag ccattgggct gctttttctt ctgtcaccaa atcaccatca
     3361 gtcccaatca catcaaaggc caagcctgtc tggtgttcgc tatagccagg acgggcagag
     3421 taacggtcag ctgctgcctt tccatcttgg ttgacataat cttgatagag cttggtctga
     3481 gtttcataac ttctaaaacc actgtaatga tcactaatag ggaaacctgc ctcttgcatg
     3541 gctttgatga gtttgaccaa ctcagccttg gctgttggat tttccccggg attatagtct
     3601 ttcgacaaag gataatgttt attggctacg atgatttcgt cgtattttcc ttggatgctg
     3661 tagtaatcac ctttattgac cacttctgct tttttctggg cagccccttg agacttactg
     3721 ccgactgtcc catcagcttt ggctgtctgt tctgtcttag ctgtaccatc ttcatttttt
     3781 gctttttctt gtgaacaagc tgctagactc aaggctagca aggctgtcac gacaaggtat
     3841 cttttcttca tttctactcc tttatttcta atagtttatc tacttctgat gataaacgtt
     3901 tgactaatct tttgatctca tccggttttg cttggcaggt ttctgctgtc atttcttcaa
     3961 aaggaaccca ccaaactgga ccacgtccct tgagaccgtg accattcata tcacctgtcc
     4021 gtcgtggaaa cagatgccaa tgaagatggg catcgccatt tcctaaaagt tcaatattca
     4081 ttttctcagc agtaaaggcc ttagcaactg cctcttggac tagactcatt tcttcgagaa
     4141 aacgtagtct tgtttccttt tctaaatggt gcaattccgt gacgtgttcc ttggctagaa
     4201 agagactata gcctgcaaaa tactggtgat ctccaatcac aagatagcct gtttccaact
     4261 ctttgacaaa atagggattt tctcccttct tgatgagctc aattctctgg catataagac
     4321 acatattagt ctaccaacgc gctcttaatg taagcatcaa ccatacgctc tgttgcgacc
     4381 accgagtcaa tatgagtacg ctcataagaa tgactagact cgatacccgc gccaaggagg
     4441 gcgtgtttga cctctgcccc tgcggacatg gccgctgaag catccgaacc ataaaatgga
     4501 tagatgtcca gcttaaaagg aatatcttgc tctttcgcca aggtcaccaa gtgttgacgg
     4561 aagtcatagt gataagggcc tgaggcatcc ttgacacaga tagacactgt gtactcatct
     4621 gtttgctggc catcgcccat agctcccata tcaacagcca gatattcgac tacctgagca
     4681 ggaatgttag aattagcacc atgtcctact tcttcaaaaa ctgaaaaagc aaaatgagtt
     4741 gttactggca attcaatctt ctctttctta taaatacgaa gcaggttgag caaaatcgct
     4801 gcgctgacct tatcatccaa atgacgagac ttgataaaac ctgtatcagt cacaacagtt
     4861 cgtggatcga agctgataaa atcaccgacc tcaatcccaa gagcacgagt ttctttttca
     4921 ttgcttactt ttacatccaa acgcacttcc atattgtcct gcgtgcgttc tgcagttcct
     4981 gcatccttgt agacatggca agaagtttgg tggatgagga tggttcctga taccttttga
     5041 cctgtgctag ccacatgaac ggtacagttt tcaccttcaa tcatgttcca aggaaaacca
     5101 ccgatacggt ccaatttaag acgaccatct ggtttgacag cacgaacaat agcacccagc
     5161 gtgtccacat gggcagtcac atagcgatgt tgctcatcat tttgaccttt gatggtcaca
     5221 ttgacaccac ccttggctgt gcgaactggc tggtaaccaa aaccttctag agtcttgact
     5281 aaataattcg aaatttcacg agtgaagccc gttggcgatg cgatggctgt cagttctttg
     5341 atatattcta ctgtttgatt catttcttca cctctttcgc tacctattat aacacattta
     5401 tcatcggata aaaaaagaaa atcactcctg tagacttggc tacaaaagtg atttaagtga
     5461 ttattccatt tcaaaaacat cgctttcttg cttgtttggt agaaccaatg agagcaagat
     5521 tccaacaatg gctggcacca accatgggag agatgccttg gcaaaaggaa gaacgctaac
     5581 aagatttgca agaaactcaa ccttaaacga gcttcctagt acgcttgcaa tggcaataac
     5641 tgtaaccaca gcaattgtca actgcatacc tggttttgaa agggcaacaa atttgttgac
     5701 aatgacaatc ataacgatag caatcgtgat tgggtacaag ataaccagta ctggaattga
     5761 gtacttgata atcgcatcaa gacccaaatt ggcaatagca aatccaatca aggtaaaggc
     5821 tgtcgcataa accttgtagc tgatttgtgg gaagcgctca ttaaagaact cagctgttga
     5881 cacaatcaaa ccaacagtcg ttgtgaagca ggttacggta accatagctg caaggaagag
     5941 ttgagctgtt gagccaaaga tttcttgagt ggcttgtgac aagatgtaaa cacctggtgt
     6001 tccacccttc atcgcttcag ctggtactgg gaaatgattt ccaagaaaac ctaaaccgat
     6061 gtaaagagcg ctgaaggcaa gggcaacaac gataccaaca acccaaatag ttgaaatgta
     6121 ttctttctta cttgaaaatc caagttgttt caaggtttga actgcgatta cgctaaaggc
     6181 cactgaggca agggcgtcca aggtattata accttctagg aaacctgtac caaaggcaga
     6241 agcttgataa gcagctgaag cagcttgagg acttgttcca ccatatttga tagctcccag
     6301 aacgaccaag ataacaatca aaattgcaaa gactggcgtt aaaatacgtc caatgcggtc
     6361 taagattttt gatggattaa gcgaaatcaa ataggctgcc gcaaaataca gaaccgtaaa
     6421 tacaatcaag ccaagtcctt tatttgcatc cgacaaaagg gggctaatcc ctacttcgta
     6481 agctgttgta gcagtacgtg gggtagcaaa gaatggaccg attgacaagt aaagaactga
     6541 gaggtaaaga gtcgcaaacc aaggcgctat cttcgttgaa atctcgtaga tatatccttt
     6601 aggatttagc gttccaataa taagggtcaa gacggcgata ccaacgcctg aaaagacaaa
     6661 acctgcgatg gcaggaagaa aatgttctcc agatagagca cctagagaag gcggaaaaat
     6721 caagttcccc gcaccaaaaa atattccaaa caggagcaaa cctgttaggg tacctttttt
     6781 agccataaaa atctccttta tatttataaa atactgacct agtataccac gattaggagt
     6841 ctgaaaaaag catcacgagg caaatattaa atgttttcaa ttttcttaaa aataagaatt
     6901 atctaaaaat aaaactctcc tacccagtcc acaccaagta ggagaaatgc aaaattttaa
     6961 agttcttcaa aggctaacat gccaccctgg acattgataa cattataacc ttgttctaac
     7021 aggaattggc aagcacgcgc cgatctcatt ccagatttgc aaataatata atgcaagcga
     7081 tctttgtcca attaatcata actatcagcc aattgactaa gcggtaggtt gtgggcacat
     7141 tctaaatgaa gagctgcaaa ctcatccact tctctcacat ccactagaga aagctggtcg
     7201 ttttggtaaa gctggtaaaa tgcgtcaaag gctatttctt tcattctttt tcttctaata
     7261 ctcttcgaaa atctcttcaa accacgtcag cgtcgcctta ccgtgcgtat gttaccgact
     7321 tcgtcagttt tatctgcaac ctcaaagctg tactttgagc agcctacgac tagcttccta
     7381 gtttgctctt tgattttcat tgactataaa atggttttaa ttcttttttt caaatctggc
     7441 actacttctg cctcaaacca aggatttttg gccatccaga tttgatttcg tggtgatggg
     7501 tgaactagcg gaaaataggc tggcagatag tctttatagt gtttcaccct ctccgttacc
     7561 ttcccactga ttttctcctg taatctgtat agctggcatt ctgtgaatcc gccatgatag
     7621 cctgtttgat tctttcgatt tgagacatct actttccctc caaaaagaag tccaagcata
     7681 agatctcaga cttctatcgt tttatttgat caattcgtaa atagcttcgg cataaattgc
     7741 tgctgctcgg aaaagatcat ccaaggcgat aaattcattg gcttggtgca tggtatcaat
     7801 cgagtctggg aacatagcac cgtaggcaac tccgcgttct agcaagcgac caaaggttcc
     7861 accaccgatg acttgttcat gacctttaag gccagtttgt ttttcataga tattcaacaa
     7921 ggtttgcaca agtggatctt ccattggcac atagtgaggc gtgtgaccgt gttcagacag
     7981 gctaacagaa acaactggca agttttcaag gattgacttg atttgttctg gacttgttcc
     8041 ttttggatag cggatgttga gggcaatggt attatcagca cttgtttcat cgaagcggaa
     8101 gacgccggca ttcatagaaa gagcacccat cttttcatcc acatgagcaa tcttaagatt
     8161 ttcaccctca tgatcgttca agagaatttt acctgcgatg tcaaggtagt ctttggctgg
     8221 accagcaaag ccaaactggc tgaggaagag ggcaaggtaa gttgcgccat tgacacctga
     8281 agcaggcata gcaccgtggg ctgatttacc aatgatcgtc accttgtatt tgccagcttc
     8341 ttcttggagt tctcctctaa gtttgtgttc tgcaacaaag gcatctagtt tagcttgcaa
     8401 gtcagccaaa tcacctgaaa cgactgctgt tgctgattct ggtaccatat tttcacgtaa
     8461 accacctgta aagctgtgaa gacgggcagc acctgtattt tctcctgcaa agtggaggta
     8521 ttccgtgata tttccttttt caccattgat gattggaaat tcagcatctg gagagaaacc
     8581 gaaatctggt ttggcaagtc ctacgtgctc aaagtagtag tccatgtctg cccagcctga
     8641 ttcttcgtct gttccaacga tgaagcgaac tttcttagaa gttggaagac ccaattcttt
     8701 gatgattttc aaaccatagt aacaagctgt tgtaggaccc ttatcgtccg aagccccgcg
     8761 cgcataaagg cgaccatctt tgatagttgg tgtgtaagga tctgtgtccc aaccgctacc
     8821 agcaggcacc acatccatat gggcaaagat tccgagaact tcttctccat caccaaactc
     8881 aaaatgtcct gcgtagttat cgacattctt agttgggtag ccatcgcggt ctgcgatttc
     8941 aaggaatttc tccaaggctt ttactggacc aggtccaaat ggatgctggg catcagcctt
     9001 gctatcatca cgttctgagt tgatttccaa aaggctaaac aagtcagcca agaggtcttc
     9061 tttgcgtttt tctacttctg ctgtaaaatc aattgctgtc attttttctt ctttctatct
     9121 tttctcgatg atttcatcta ctggcaagcg gtagcttggt tccaatttgt cgtctgtgta
     9181 acccactgtg atcaagagtt ctgggcggaa acggtcttcg atttccaaaa cttcattaac
     9241 ttttgatttg tcaaaaccaa ggataatatt ggaaccaatt ccttggtctg taagagcgag
     9301 aaccaagttc atagcaacca aacctgcatt gagtgctagg tagtcgctga cttgttgttc
     9361 attgtagcgt gcaaattcag ctggcaaatt tttcatgaag tattgaagtt gttcttctga
     9421 gaaattgtta gcaccaccaa ctcgggcaat cttacgagcg cgtttggcaa ggtctgtatc
     9481 tgtaaatagg gcaatggtta caggtgctga tgatacctgc tcaaagtttg aaccataagc
     9541 caactttgcc agttcagcat ttttctcacg aacaactaca aatttccaag gctggctgtt
     9601 gtgggcgctt ggcgccaagg ttgcaatttc gatagccgta cgcacatctt ttggatcaac
     9661 aggcttatca gtgaaatgct tggtcgcatg acgtttttta tttaattcaa gaaatttcat
     9721 aatcgatttc cttttctaat tctactgctt ccattctacc ataatttgaa agagcttgca
     9781 gggatttttc atgattaagt ttttctatca cagacataaa agatatatat tggtttatta
     9841 ggaaagtttc tgataaacta gcaagtactt tacatttgaa tggagacagt atgaaaaaac
     9901 ttagcctatt actagctatc ctaccatttt tggttgcctg tgggaatcaa gctacaccca
     9961 aagagactag cgctcaaaag acaatcgtcc ttgctacagc tggcgacgtg ccaccatttg
    10021 actacgaaga caagggcaat ctgacaggct tcgatatcga agttttaaag gcagtagatg
    10081 aaaaactcag cgactacgag attcaattcc aaagaaccgc ctgggagagc atcttcccag
    10141 gacttgattc tggtcactat caggctgcgg ccaataactt gagttacaca aaagagcgtg
    10201 ctgaaaaata cctttactcg cttccaattt ccaacaatcc cctcgtcctt gtcagcaaca
    10261 agaaaaatcc tttgacttct cttgaccaga tcgctggtaa aacaacacaa gaggataccg
    10321 gaacttctaa cgctcaattc atcaataact ggaatcagaa acacactgat aatcccgcta
    10381 caattaattt ttctggtgag gatattggta aacgaatcct agaccttgct aacggagagt
    10441 ttgatttcct agtttttgac aaggtatccg ttcaaaagat tatcaaggac cgtggtttag
    10501 acctctcagt cgttgattta ccttctgcag atagccccag caattatatc attttctcaa
    10561 gcgaccaaaa agagtttaaa gagcaatttg ataaagcgct caaagaactc tatcaagacg
    10621 gaacccttga aaaactcagc aatacctatc taggtggttc ttacctccca gatcaatctc
    10681 agttacaata acactcttcg aaaatctctt caaaccacgt cagctttatc tgcaacctca
    10741 aagctgtgct ttgagcaacc tacggctagc ttcctagttt gctctttgat tttcattgag
    10801 tataagatat actaaaagcg attggaccag ccaatcgctt ttttagtttg cattggctat
    10861 tttaggaaac tcttacaaaa aatcaaaaaa attcttcaca tcctctacat acccatgctt
    10921 ttctattaag ctggctaata attccagatt gtgcccctga tagttatcgt cacgacgcag
    10981 ttcttcatac atttcgataa agggaagccc cttggacttg gccaattcta actcagcttc
    11041 gtaatcataa gcaactttac gaaattggat attgagtaat tccccatctt caacttctat
    11101 cacggcatac tgggcacggt gattttttaa cgcctcccaa ttaaaatagg gcatgccaat
    11161 cgaccctgta ttgatgattt gttgcccttg acttccataa cgaagcaact gcttgtgaac
    11221 atgaccataa actgccacgt ccgtttccgc atctagcagc tggtcaaatt tctctgtatc
    11281 attctcaact agcaagtcac caccatagtt tttgtcaggt aaattatgag agatagaaaa
    11341 gcgcaatccg tcaatttctt tcttttccag caaaggcaag cttcgtagcc agacaatcgt
    11401 tgcaggatcc attcgctcca tcaaaaactg ggtcatgcgc attgactgga tttctttcgg
    11461 atattccaaa ccatattcgc catccaagac ctcaaggaca cgatcatccc aattgcctcg
    11521 aacacttgct gtgataggaa ggtcctttag cagggcgact aagtcatttg cgcctggacc
    11581 aggaagaaaa atatctccca gaagccaata ttcactggcc ccttgatttt tagcatctgc
    11641 aatcactgct tctagcgccg tcgcattgct atgaacatct gataaaattg cgattttatg
    11701 gttcattgtg gtttccttcc gtttggtaat ctactctttc ttctgctact tgaggcaagg
    11761 cttctccctg cgggttcaac tttctttgca cagcctctgc aacgactcta ggtaccccaa
    11821 cttcgacaat ctcatccaca ctggcttcct tgattttggt caaagacttg aaatgcttca
    11881 taagattctg cttgcgttta ggtcccagac cgtcaatccc atccaattga gatgagaaag
    11941 aatttttgga gcgcagttgg cggtggaaag tgatagcaaa gcggtgcacc tcatcttgga
    12001 tgcgttggag gaggaaaaat tcctgagaat tgcgagacaa gtccaccacc tcaagcggat
    12061 ctccaaagag caattcatgg gtttggtgct tatcattctt ttgcagccca gcaattggaa
    12121 tatccaagcc cagttcctct tggataacct gcttagcgat attgacttga ccttgccccc
    12181 catcaatgac aatcaaatct ggaggagtca aagcctcacg ctgtactcga ccatagcgtc
    12241 tgcgaatgac ctctctcatg ctggcatagt cgtctggtcc aacaaccgtt tttatcttgt
    12301 acttacggta atccttctta ctcggtttac cgttgacaaa gaccaccata gccgaaacag
    12361 ggctagttcc catgatatta gagttatcga aggactcgat acgtactggg gtcgggattt
    12421 ggagcaaacg ccctagattt tcaatagctc cttgagtctt ttcgacagat ttttctagca
    12481 gattgaactt ctgctctaga ctaacacgag cattttttat ggctagattg accagttgtt
    12541 ttttctctcc acgttgaggc ttaagaatct tggaatccac caaggccttg acagcctctt
    12601 cgtcaatatc ctgcggaatc agtacctcat tgggaactag atgagatttt tcttgataga
    12661 attgtcctac ataggtcaaa aaatcctcat ctggatcatt gaagtagggg aagagattga
    12721 catcgcgctc gataagctta ccctgacgga caaagaaaac ctgcacacac atccagccct
    12781 tatccacata gtagccaaag acatcgcgat tttgcaaatc tttcgccatg acccgttgct
    12841 tggttcgaag cgttccaata gcctgaatca ggtcacggta ttccgccgca cgttcaaact
    12901 ccatactttg tgctgctact gccattttac tcttgagatc atcgatgatt ttgtcatcct
    12961 gacctttcag aaaatcagac acctcctgag ccatagactt gaaataagcc tcatccttct
    13021 tacagatggt gtgggccatg cattgaccga tatggtaata aaaacagacc ttagagggcg
    13081 ggttggtaca cttacgaaaa gggaatatcc gatccagcaa ccgcttgatt tcattggctg
    13141 cccccacatc gggatagggt ccaaaataaa gacctccgtc ctttttgacc tgacgagtga
    13201 taatcaagcg tggatagcgc tcattggtga ttttgatgaa aggataggac ttgtcatcct
    13261 tgagcatgat attgtacttg ggcttgtttt ccttgatcag gttgatttct aggagaagtg
    13321 cctcaatatt agactccgta acaataaatt caaaatccac aatttcagac accagagcct
    13381 ctgtcttggt atcatgactt ccacgaaaat aggaccgtac tcgattacgc agatttttag
    13441 cctttcctac atagataatg gtgccatttt tatccttatg aatgtagcaa ccagggctgg
    13501 tcggcaagag ctctagtttt gatttaatca agttgttcat agttccatta tagcaaaaaa
    13561 gtagggaaag atagtaccct actcactagt ctcatatatt tttcggaggt ttgcaacatc
    13621 ctcttcctgg ataccataaa aggaacctgc tggttgcatg acagacttct catctgtatg
    13681 gtccaagcca atcgcatgac ctaactcatg ttctgccgta tggacaaggc gttcatagga
    13741 gtagccatag tatggattgg acaaataata atgattcaac cgcaccgtta cggacaagaa
    13801 ttgccctgtt aagagattag tttgactttc cgcctctcct gccacaggag tgcctccgtc
    13861 gttcatctcc gtagccgtaa tatccgcctt actagactca gtcacgagtt caaagttaaa
    13921 agcaccagtt tgattccagt tctggattgc ttctaaataa gcctcttgaa agcgtgaatc
    13981 catctgcgga tccaggtaaa tacgagcaga ggcctgtgcc caccttcctt cagaatgctg
    14041 gtgactatct gtctggctta acttaggcag ttgccctgtt ttctcccatt ggtcaatact
    14101 ttgttgacca atttttactg accgttctgc ttgctttagc gctccttgaa aatccccgtt
    14161 cagataccag agaagtccga aagcaagcac acataagagc acaactatcc aaaccagacg
    14221 ccaaaacaaa cgccacacaa aagaaaagaa agcccctatc aaacgaaaaa gccagcgcat
    14281 gtctctccac ctttctagca aataagaatt attttactaa aagaagctaa aagaaatcta
    14341 aatactgact ttttcatctt aacgtcctac tatttttttg agtaactgga tagctttgta
    14401 ttttaaaggc gatggatggt aacggaaagt acccgctttg cgtacaatat agccattaaa
    14461 attctgttta aaacgcaaaa caccatcact tccatcaaaa atcccttgaa tgcctaggaa
    14521 gttgtattta ggtattccac gttttatgct ttccaacata acatattttt gaagcagggc
    14581 aggggcatag aacttattaa actcagtgta ggaaccacta aagagataag tcgtttcctg
    14641 aggcatataa acaaataaac tcccagctaa aacaatatct tcttctccat atttttcaat
    14701 caagtctcgc gcttctgctt ttcgaacttc aaacgtttca aattgactag aatattctct
    14761 cagttgattt tgtttttttt cagaatgagg atttttactc aaatcaagtc gcaacttgtc
    14821 caagttttct tctagtttac tttgttcacc ttgcaatttg ctcatatact ccgaaaaatt
    14881 caagcttgct atgagaaact ccgcttgttc tccaaaagta tcataaaaat gctcataata
    14941 ttctaaactt ttatcactat attctctacg ttcagaggtt tcttttgtta tattcttaaa
    15001 aatcgatagt tcttcacgtt ttaacttttt caaccgaatg ccaaaggttt cagccttttt
    15061 caccaagggt ttaccctttt tgctaaaact tttaagcaaa ctcttttcag ttaattcagt
    15121 taaatcttta tagtataacc aatctggttc tccacctggg taacctgttg ttaagccatc
    15181 aaattgataa cctaaatcag tcaaaccttg aataatactt tttttctcag catctattgg
    15241 attaccttgg ctatcaaaag tttgataagt ttcataaggt tttacaagca actctaatac
    15301 accattttgc ttggcatatt cttttaactc tgcataaaaa actggaagag catcttgttg
    15361 ggtataaatc ggccccgaat tgagttccat atgcagacca cccagcatgg gcaagctata
    15421 aaccagagct gcaacttgaa tttctccttc ttgtttcaaa gcaagataaa caattcgagc
    15481 ccctcttttt tctagcaaat cccccatctg gacagattgc ataaaggaac gagaagaaac
    15541 ctgatcagaa taagtctgaa actcttcttt cgtgagtgtt gttagtgcca tatacttact
    15601 ttctatgttt ttttcttaat gttttacgga aatcaagagc aagtcttaac agaggataga
    15661 gaggatgagt gggcattgta aattcaccca agtattcttc aatcgttgga ttaaattttt
    15721 ccttaaaatg ataaagtcca ccattgagag agttttcaac accacctaaa ttttgccaga
    15781 ccatacctcg ctcaaaggca tagcgagccg tttcatacca tgttaaaatt ggtgcattgt
    15841 aacgtttaaa atcatcatcc ataccagcat atatattgac agaggtagta ccaaattcca
    15901 aactcaaagt agccgctaaa ggaactctcg cttgacctac atctatatat tcctgcaaga
    15961 aggtcaattc ctctaacaaa cgttcttttt ccttcttctg cgcttctact tttgaagttc
    16021 gagtcgactc agtaaaggtc tcttccaagg ctctattttt cgctaactgt tcttctaatt
    16081 cttgcgaacg tttagaaaca tccaaggtgg ccaaggtgat ataggccttg tccttaaaat
    16141 tatctaacaa ttttttataa taggcttcat tcctcaaatg aatctctttt cgcttctcag
    16201 tttttttcat caactccgaa aatgaatcta atagttccag tccaccatat tgaatctcaa
    16261 gccctttgtt tcgtgctgtt cgaatagcct gttttgttga cttggaaagt ttatcttctt
    16321 caaaattttc cttgtatatt ttcgcctgaa tacgaggttg aatggtgtct cccatttcct
    16381 ccgtttttcc tgaccacctt actcccattt gttgcaaact atcaataata gccagatttt
    16441 caggaaattc tgtcttttcc tgattgatta aactttgaga taggcaaata cttgggtcaa
    16501 aagtcacaaa aaccactctc ttactgcgag cataggactt aatagactga atggcaaaat
    16561 tcaagagttc tttatcccca taatccaata taggtcctct tgggatgtaa aacattttat
    16621 agcctagcgg aagagttcta atcaaaatac tagctgtcgc cagtaatttt tcttccctgt
    16681 aaacaccaaa cttctcatgt tgccaattag acttaacttc ctcccaagca ctactttgta
    16741 atacattggc taattcatgt tctttgacaa actgatcata ttctaatgtg ggaatgccaa
    16801 tttgataacg gtacatttcc tactctcttt cctccagtat tttattacta ttctactact
    16861 ttcgtttgaa aagtctagtg aaaacatatt ttatttcagt tctactcccc ctatgctgaa
    16921 gttcaaacta agtcagtctc tcttctaatt tgaaatcaat tggtagggtt gttaaaaaaa
    16981 cttccaattg tttttcccag tagtaccact cgtgagttcc agcgctatgg ctataggtca
    17041 catcaaaacc tagttttttg agatttttca ctgcgagatt attggcttcg tacaagaaat
    17101 cctgttcgcc acaccacgcc caaagtttgg tctttttatc cgatttttta gccagacttt
    17161 caagagaata gggactagtt gtccagtctc taatctctcc aaaaacacct ctccagtagg
    17221 ctggacttcc cagattttga ctttcaggag aaaagttttg aaagctgagg gcacctgaaa
    17281 aactagctgc atgagaaaaa cgatttgtcg taagagccag tttgaagcag ccgtagcctc
    17341 ccatagaaag accagcgata aaggtctttt cacgcttgct cgtcatatta gggaagaagc
    17401 gtttcagaac ctgtggcaat tcctctgcta gagccgtgta gtagtcaaaa ccatactggg
    17461 tatcggtgta ccaaccattg ctggtattgg gcataacaac gatgagatta gttcctcgaa
    17521 gcaagcgttc tacattggtc cgcttaagcc aactattatg atttccagac atcccgtgca
    17581 aaaggtacaa gacgggaata tcttcacact ctggttcttc cactcgattg gcatcagggt
    17641 agaggacatt caccccccac tccatatcca atacttgtga gtaatactcg attttcatta
    17701 ctgccatgat tttctccttc tatttttcta taagaaaaag ccgaaactcg actttctctc
    17761 tgtttatttc aacgattatt ttgcttccat gactactggt aaaatggctg ggcgacgctt
    17821 ggtttgatca aagaggtact tggtcagatt gtcacgaacc ttacctttaa gatctgccca
    17881 gtcaaagtca tctccttgaa gataatcttc taccgtttgg ttaatcaatt ctgaactttc
    17941 acggagaata tcgcgactct tcttgagata aacaaatcca cgcgtgtgaa cacgagccct
    18001 agccacaatt ttcttctcac gacggttgac tgtaatagcc acgatgaaaa ttccatcctc
    18061 tgacaagacc ttacggtcac gaagaacaac atttccaaca tcaccaatgg cattcccatc
    18121 aatcaagata tctcctgctg aaaccgatcc agctggaaca aagtctccat tctcgtaagc
    18181 catggtcgtc ccctttttag gaatgaaaat gcgttctggc aacatcccaa ctgccatggc
    18241 agccttagcg tgagcatcca actcacgata ctccccttgg acagggaaga ggtacttagg
    18301 ttgcaaaaga ttgatcatca gctgcaaatc acgcacattt ccgtgccctg atacatgtaa
    18361 actttgggta atcaatttga caaccccacc tgcctgataa atcatatttt ccacacgcgc
    18421 aacaaaggct tctttagcaa tagacggagc cgtagcaata tagaccaggt ccccatcctt
    18481 gatttctaca taacgatggc gaccaatcga catcttacga agtccattga taggttcacc
    18541 catacgacct gtctcaagaa taatcaactc atggtcttca aagcgagaca tatctttagg
    18601 cttaatcaag agaatttcgt tggctaaaga caacttctta agacgaatcg ctgtgcggac
    18661 gatattttca atatcaaatc ctgtcaagac gatacgtcga cctgttttat ccgcagcgtc
    18721 aaaaatctgc tgaatacgag aaagattact ggaaacagct gcaacgatga tgcgaccttc
    18781 ccagtcagca atagtttggg taatttcatc cctaacttca ctttcactag ccacctgaat
    18841 attgctgtct gcattggccg aatcactgag gagagccagg acgccgtcac gaccaatctc
    18901 tgccaaacga gcaaaatcag ttgcataaga ttcactagcc gtttggtcaa atttgaagtc
    18961 acctgtataa acgatgcttc cttccgatgt cttcaagaca attcccagac tctctggaac
    19021 ggagtaagtc gtagggaaga aggaaaccac tgtcccacca aaatcaatct ccgtattctc
    19081 atcaatgaca tggaaatcat taaatttctt aacggcatca tttcctttga caaagagctt
    19141 tgccaactca atggtcaact cagacccaaa tacaggaact ttagcctctg ccaagagata
    19201 aggtagagca ccaatggcat ccgcatgccc gtgggtcaag aaaaccccag caatacggtc
    19261 gctattttca aaaaggtaat ccatgtttgg aatcaccaca tcgaccccta attgttcatt
    19321 ttcaggatat tttaacccta cattcaaaac aaaaatggac tctccaattt cagcaatgta
    19381 catatttttt ccattctcac gcacaccacc aagtgttgtt aaactgatat tactcatttt
    19441 tcctccaaaa tcttagttta tcttgattat agggcaattc taccctctta ttctaaaagt
    19501 tctgatactt tcagccgaat cttttcctac cattatacca tttttttgat gattttcaaa
    19561 atgaaggtct gttttcaaaa aagagttgat ttcccaactc tttcctaact tctactcttt
    19621 ttccatcaaa aaatcataaa tttcttgcac cgtacccagc gccatcattt cttggtcttt
    19681 aacggtttgt ttgagatttt ggtaaatttg actttctcct atctcccgct ttggcgcctc
    19741 tttattgact gtcatcacac catcttttat cgtcacaaag cctagttctt caaatacttg
    19801 aatcatcttg accagcaaga tttgttgaat attaagatat gcagccaaat ctttcagctt
    19861 gtagcgaata tcaaactctg ggaactggta aatagtcttg tacaatttgg caaactgatc
    19921 tctagtccca taacctgtca gataataagc cttgtcaata tcatttttga aatagacagc
    19981 agagaaatgc tgttcctgaa aaatggtctt cagctgagta atatcctctg gaatgttttt
    20041 tacgacaaca gcttcactag ccgcaagatt tggcagttct ccaggaaaat ccaagactgg
    20101 aacaccttct ggcaagactg cattttttcc acgaatgtta aaaagttgaa caccttccac
    20161 tcgcgcatcc accatcatca actggagggc agtttggcca ttccattggt tgacagacaa
    20221 tttaaccgct aactctagat tcttggtttg agaaaactct gtcgcccatc tgccttgacc
    20281 aaaggctacc acttcaaaac tcgcctcacc cttggaaatt ttcagcttta gatgggcatt
    20341 acctgccccc atagtacgag cactttcgac ctgaaaattc ttgatataaa aaataggttt
    20401 ctgattatcc attccaaaag gagctaaacg ttcaaaactt ttgaccgttt ccaagctaag
    20461 tgcctccaaa tccaactctt catctaggtt taacttattc ttgccaccag catctgcacc
    20521 tttttcacga acataatctt ccaaaacctg agataaatct gagagttgct caacttccag
    20581 cgtcataccc gctgcacctg catgacctcc aaaggcgatg aagaggtctc gatggggatc
    20641 cagagcttca aaaatatcga ccgcttccac actacgagca ctgcccttgg cacgaccgtc
    20701 ttctatatta agaacaatga ctgtctgtcc caattcttcc aataaacgac cagccacgat
    20761 tcctagaacc ccaggattcc agccttcctt ggccaagacc tgaaccttct tctcaggatc
    20821 caccatggtc ttggcttctt catagataga ctgaacgatt tccttgcgct cttcgttttt
    20881 ctggtgaatc ataagggcaa tctcatgcgc ttcctcatca tcaaatccag tcaacaaatc
    20941 aatggcagga ttgggatcat ccaagcgacc caaggcattc aaacgaggag caatctggaa
    21001 accaaccgtt tcttctgtta cttcgttggc agcaatccca gccatgtcca gcatttcttg
    21061 cagaccaatg cgctgggtat gacccaacat ttccagacca tattgaacta agatacgatt
    21121 ttcatccgtc agactcacca tatctgcaat agttccaata gcgaccaaat caagcaattc
    21181 cacttgcact tcttctaaca gggcacaagc caacttgaaa gcaactccac aaccagccaa
    21241 atatttaaaa ggataatccg catctggatg ttcaggatgg acaatagcat aagcatctgg
    21301 cagggtttca ggcatggaat gatggtctgt cacaatgaca tctactccca tagactgagc
    21361 caatgcaata gcctcatgac cagcaacccc attgtccacc gtcacaatca aggaaatccc
    21421 ttcttgctcg ataaagtatt tataaacact agcattaggg ccatagccat cggtaaaacg
    21481 atttggcagg taaactcggc actcagcacc aagttgttcc aaactttcct tcacaataga
    21541 agccgaagtc atgccatccg catcatagtc tccataaaca agaatatttt ccccttcttc
    21601 aatagcctga cgaatccgct ccactgcctt gtccatatca tggagcagat aagcatcatg
    21661 taagtcctcc aaggaaggtt ctaaaaactt cttcagactt tcttggttct gaatccctct
    21721 ctcaaacaat aaccgagcca cctcaggacc cagtccagcc ttcttggcta tctttgtaaa
    21781 atccgcatct tctacctgca gggcaaactg ccattcataa gtaggtgtta tcaaaaagac
    21841 atccactctt tctaagaatt ctattgcttc attataacat gatttagacg ttttctctat
    21901 ccagattgct tttttataac attttatagt atattgaaac tagaatagta cacctctact
    21961 tctaaaatat tgttagaaat cgatttgact gtcccgatcg atttttcctg ttcttatttc
    22021 actatagtga attttttcag atatggtttg acaagaacat tcttttattg tagaaccgtg
    22081 ttataaaata taacacaaca gagatctctc atggctttag tagaatttaa aaacgtcgaa
    22141 aaatattacg gagactacca cgcattccgc aacatcaatc tccgttttga aaaaggacaa
    22201 gttgttgtcc tgcttggacc ttctggctct gggaagtcca ctcttatccg tacgatcaat
    22261 ggtttagaga ctgttgacaa aggaagtctc ctagtcaatg ggcaccaagt tgctggtgcc
    22321 agccagaaag atttggtacc tcttcgcaag gaagtcggca tggtttttca acattttaac
    22381 ctttatccac acaaagctgt gttagaaaac gtaacgcttg cacccattga agttctagga
    22441 attgataaaa aagaagctga aaaaaccgcc caaaaatatc tggaatttgt aaatatgtgg
    22501 gacaagaaag attcctatcc cgccatgcta tctggtggac aaaaacagcg gatcgccatc
    22561 gctcgtggtc ttgctatgca tccggaactc ctcctctttg atgaaccaac atctgctctt
    22621 gatcctgaga ctatcggaga tgttctagca gttatgcaga aactggcgca tgatgggatg
    22681 aacatgatca tcgttaccca cgaaatgggc tttgctcgag aggttgcgga ccgcattatc
    22741 tttatggccg acggagaagt tttagtagat acgacagatg tcgataactt ttttgacaat
    22801 ccaagcgaac ctcgtgccca acaattcctc agcaaaatta tcaaccacga aagtgacaaa
    22861 gtcaaataag gaggcgccta tgaaaaaaaa attcttttta tcagcattat tgattagcct
    22921 tttcggcctt gctgctgcca aaccagtcca ggctaatact agtatcgcag acattcaaaa
    22981 aagaggcgaa ctggttgtcg gtgtcaaaca agacgttccc aattttggtt acaaagatcc
    23041 caagaccggt acttattctg gtatcgaaac cgacttggcc aagatggtag ctgatgaact
    23101 caaggtaaag attcgctatg tgccggttac agcacaaacc cgcgaccccc ttctagacaa
    23161 tgaacaggtc gatatggata tcgcgacctt taccatcacg gacgaacgca aaaaactcta
    23221 caactttacc agtccctact acacagacgc ttctggattt ttggtcaata aatctgccaa
    23281 aatcaaaaag attgaggacc taaacggcaa aaccatcgga gtcgcccaaa gttctatcac
    23341 ccaacgcctg attactgaac tgggtaaaaa gaaaggtctg acctttaaat ttgtcgaact
    23401 tggttcctac ccagaattga ttacttccct gcacgctcat cgtatcgatg ccttttccgt
    23461 tgaccgctct attctatctg gctacactag taaacggaca gcactactag atgatagttt
    23521 caagccatct gactacggta ttgttaccaa gaaatcaaat accgagctca acgactatct
    23581 tgataacttg gttactaaat ggagcaagga tggtagtttg cagaaacttt atgaccgtta
    23641 caagctcaaa ccatctagcc atactgcaga ttaaggagga caccccatga cagatttatc
    23701 atcttggaca gcctattttc aggattttgg acaatttttc aatggtttcc tcttcaccct
    23761 tgccctagcg gttggttcct ttatcctcgc tatggttttg ggcatcttct ttggagccat
    23821 gtcaaccagt aaacgtccga ttttgcgaat cttagctcgc atcttcgtgg aattttacca
    23881 aaacactccc ctcttggtgc agtttgttat tgttttttat ggcctacctc ttatcagtga
    23941 ccatactatc atgattccaa tttattggac agctgttctc tgcgtgggac tctatcacgg
    24001 cgcttatatc gctgaggtta ttcgttcagg gattcagtct attcctagtg gtcagatgga
    24061 ggccgccttg tcgcaaagtt ttacctatat cagtgccatg cgcttgatta ccttgcctca
    24121 ggccttccgc atcattctcc ctccattgac caaccaaatt gttaacctca tcaagaacac
    24181 ctctactgta gctatcgtct ctggagtaga cttgatgttt gtgactaagt cttggtcggc
    24241 tctcaacgga aactatatcc caggcttttt aggtgctgct cttctctact ttgccctatg
    24301 cttccctgtt gcccagtttg gtcgcaagat ggagcaagcc aacaaaaaag cctattcact
    24361 ttaggaggtt actatggaat ctattttaga agttttaacc ccagataacc tagtctttat
    24421 atttaaagga tttggcttga ccctctatat ttctctgatt gccatcatcc tctctactat
    24481 catcggtacg gtgctagctg tcatgagaaa tggcaaaaat cctatcttac gcattatttc
    24541 cagtatttat atcgagtttg tgcgcaacgt tcccaacctt ctctggattt ttactatctt
    24601 tttggtgttc aaaataaagt ccacaccagc aggtattaca gcctttactc tctttacatc
    24661 agcagccttg gctgagatta ttcgaggcgg tctcaatgcc gtagacaagg gacaatacga
    24721 agcaggaatg tcacaaggct tcacctcagc ccaaatcctc tactacatca ttctcccaca
    24781 agccatccgc aaaatgctac cagccatcat ttctcagttt gttaccgtga ttaaggatac
    24841 cagtctcctc tactctgtta tcgccctaca agaactcttt ggagccagcc aaattctcat
    24901 gggccgttat ttcgaaccag agcaggtctt cagtctttac atcctgattg ccctcatcta
    24961 cttcagcttt aacctagcaa tttctagcct gtctcatatg ctagccaaac gttggcaaca
    25021 agctgcagaa taacactctt cgaaaatctc ttcaaaccac gtcagctcta tctgcaacct
    25081 caaaacagtg ttttgagcaa cttgcggcta gcttcctagt ttgctctttg attttcattg
    25141 agtataaaca gccactctcc agttcaattg gagagttttt tgatgagagt agatatttat
    25201 agacctcaat ttgacaccat acattttcta tgataaaatg taacaaattt atttacaaca
    25261 aatcgaaatc taaatgaaat ggaattttct atgaaatcag tcaaaggact actctttatc
    25321 atagctagtt ttatcttgac tcttttgact tggatgaaca cttctcccca attcatgatt
    25381 ccaggactag ctttaacaag cctatctctg acttttatcc tagccactcg tctcccacta
    25441 ctagaaagct ggtttcacag tttggagaag gtctacaccg tccacaaatt cacagccttt
    25501 ctctccatca tcctactaat ctttcataac tttagtatgg gcggtttgtg gggctctcgc
    25561 ttagctgctc agtttggcaa tcttgccatc tatatctttg ccagcatcat ccttgtcgcc
    25621 tatttaggca aatacatcca atacgaagct tggcgatgga ttcaccgcct ggtttaccta
    25681 gcctatattt taggactctt tcacatctac atgataatgg gcaatcgtct ccttacattt
    25741 aatcttctaa gttttcttgt tggtagctat gcccttttag gcttactagc tggtttttat
    25801 atcatttttc tatatcaaaa gatttccttc ccctatctag ggaaaattac ccatctcaaa
    25861 cgcttaaatc acgatactag agaaattcaa atccatctta gcagaccttt caactatcaa
    25921 tcaggacaat ttgcctttct aaagattttc caagaaggct ttgaaagtgc tccgcatccc
    25981 ttttctatct caggaggtca tggtcaaact ctttacttta ctgttaaaac ttcaggcgac
    26041 cataccaaga atatctatga taatcttcaa gccggcagca aagtaaccct agacagagct
    26101 tacggacaca tgatcataga agaaggacga gaaaatcagg tttggattgc tggaggtatt
    26161 gggattaccc ccttcatctc ttacatccgt gaacatccta ttttagataa acaggttcac
    26221 ttctactata gcttccgtgg agatgaaaat gcagtctacc tagatttact ccgtaactat
    26281 gctcagaaaa atcctaattt tgaactccat ctaatcgaca gtacgaaaga cggctatctt
    26341 aattttgaac aaaaagaagt gcccgaacat gcaaccgtct atatgtgtgg tcctatttct
    26401 atgatgaagg cacttgccaa acagattaag aaacaaaatc caaaaacaga gcttatttac
    26461 gaaggattca agttcaaata agtaatcata ctctcctggg atttcccagg agagtttttt
    26521 atagccaaat gaaataagac cggaacgatg gaattttggc attcaaatca attgataaga
    26581 atattttata gtggagtgaa ataggatacg aacaaattga ttaggaaaat caaatgaatt
    26641 tatagaaatc ttttagcagt tatgttgtcc tgttctagtt tcaaaacgct atagaaacag
    26701 cattgtgcta gtctagattc agtttactat actaaaacga gtagcttgaa atcaaaaaac
    26761 ccaccctcac aggcaggttt tatctgtatt attcagctag attatgcttt accttctgaa
    26821 ccgaatacgt cgatacgttc ttcaaccgat gcttggatag cttttacacc gtcagccaag
    26881 aatttacgtg ggtcgaagag ttttttcttg tcgtattctg cttcgtttgc ttcgtagtca
    26941 cgagcaaatt tacgagttgc gttagcgaat gcgatttggc attctgtgtt aacgttaact
    27001 ttggcaacac caagtttgat agctgcttgg atttgctcat caggaatacc tgatccaccg
    27061 tgcaatacga ttgggaatcc tggaagagct tctgtcaatt tttgcaagtg gtcaaggtca
    27121 agaccttccc agtttactgg gtaagggccg tggatgttac cgataccagc tgccaagaag
    27181 tcgataccag tttcaaccat tgctttagcg tcttcgattg gagccaattc acctttaccg
    27241 atgattccgt cttcttcacc accgatagta ccaacttcag cttctactga gataccttta
    27301 gcgtgtgctt tttcaacaac ttctttagcc aatttaaggt tttcttcaac tggaaggtgt
    27361 gaaccgtcaa acatgattga agtataacca acttcgatac actcaagtgc atcttcgtag
    27421 tgaccgtggt caaggtggat agctactggt acagtgatac ccattgattc aacaaggtta
    27481 gcgatcaagt tgcgagcaac tttgtaacca cccatgtatt tagcagcacc cattgaagtt
    27541 tggatcaaaa ctggagcttt tttagcttct gctgcgcgca agatagcttg agtccactca
    27601 aggttgtttg tgttaaatcc accaactgca taaccgttgt cacgggctgc ttggacaaat
    27661 ttttctgctg aaacgattgc cattttatca ggcctcctgt atatttttat gggtcatccc
    27721 atttacattg ttcattttat cactttttgc caaaaaaatc tagtttttcc cgcagtttcg
    27781 attgattttc ttctaactcc atctatgtaa accctttctc tccctagtct tggacgactt
    27841 ttggaaaatc tataaagaag gttaaacgat tctcctccat ctcgaaacga taagctaatt
    27901 tttcatgttc taatagactc ttaaccacaa agagccccat accagacccc ttgaccttgc
    27961 gactagcatt gtcagaaaaa gactgggcta gtttttcttg ttcctctgag ctacagctat
    28021 tttcgataaa aagttctcct tctctttctc caattcgaac taagccacct ggaacagagt
    28081 gcttaatggc attgctgatg agattagaaa gaatcaactt cataactgat gggtttagat
    28141 aagcctgctg atgggtcaaa ctattgtcta tctggagctc tctttccttg gctagcaagg
    28201 cataatcttt gaccagattt tgcgtcatct ggaggaggtc aattgtttcc ctatcatctc
    28261 gcaattcctg cacagaagag agggaaagta tctgcagaac atggtgattg agttcatcca
    28321 caatccccaa ggcaactccc agatactggt ctctatcctt ataacgaccg atattctctc
    28381 tcatattttc gattaggatt ttcaaactag ccagcggtgt tttcaattca tgagaagctc
    28441 ctcgtaggaa ttcgaccttc atcttctcca gctggagaat ggcttcattc ttttcatgca
    28501 agtccgcaat aacagtcaag agatgctggt agaggctatt gatttgttcc ttgagattac
    28561 ctatctcatc cttagaatcc acgcgcaatc gcacttggga atccaggtcc atcatccgac
    28621 gggtcacccg cttgatttcc aaaatcggtg caacaatagt ccgagcgtag atgtaggcca
    28681 ccaagaggga aatcagaaag gaggccagca aggtataggg aagaaactgg agactgattt
    28741 gctccgcttc cttttgtaaa tccatggaag ctagaaactg gagaatcata gtagcaccgt
    28801 cttgcgtttt cacctcgcgc tcctcaataa agagagaggt tgtctggcgg tctgtgtcca
    28861 gaggaagact gtccttgact tctaacttgt cctcggtcat ctcacctttg acggtcccct
    28921 tgatatcact agtctgggaa tacaagtcta acacttgctc gatactctgc ctatctttcc
    28981 cttctaggga ctgggcaatg gctgttgcct tttgaccaat ggtttcctga cgatgactca
    29041 gataagtcga aggaaaaaga aaataaatag ctaaatgaag gcagataacc agaacactaa
    29101 atatcgagaa ggtatagata aatatctttg caaataaacc tgttcgtttc attttcgctc
    29161 caatttataa ccaacattgc gcacagtgag gatacaatcc aagtctagct ttttccgcaa
    29221 ttccttgata taaacatcaa taacacggtc aaagggaacc tcatctgtcg ctttccagac
    29281 ggcatcgata atctgagatc gagtcaaggc ccggccttca tttttcacta gatagtccag
    29341 aatttccaac tctttggcat tgataggcac ttcttgacct gcgatgcttg cactgtagct
    29401 ttcaaagtcc accttggtat ccttgtaaga aaagattcgt cctgtatcgt agtagcgctt
    29461 gaaaatcgcg tccaccctca cttttaagag ggagagggag aaaggttttt ccagatagcc
    29521 atctgccaaa gaggcaaagg cactcatctt gtattcctca tcctgaaaag ctgtcaacat
    29581 caagacagga acctgactgg ttttacgaat ctcagctagg acttctaagc cgttgagctt
    29641 gggcatctgg atatccagta aaaccagggc cacctcatag ctagaaaatt gctccagagc
    29701 ttcctgaccg tccgctgcct caatagtttc atagccacaa tccgtcaaat aatcactgac
    29761 cccctcacgg atcatctctt catcttctac aattaaaatt ttcatacttt aactgctctc
    29821 tattttttat ttttcttaga ataaatacct actctatttt ctattatagt ctcttgctgg
    29881 ccttttgtct gtaagcaact gaccactaga taaaacgttg tgaaattcct ttctcataaa
    29941 ttccataact ttagtatatt atatttaagc actaaagtac aaagaaagca actgaaagca
    30001 atgattttca ccactgcttt cggatttatt ttgaattgtt aaatagccat tcctatccac
    30061 tattcttgaa tagaaacaca agatgcaatc tttattccag actcattttt tcaaatttat
    30121 tcaccatcca gcaagagctc ttttggttgt tttctaagga gattgcttga agcaagcgcc
    30181 ataacgagaa ccactagaac caaggcaagg acaaaaatga tgataaagtc tgatgtctga
    30241 atggaaatgt ctaggctcga caaggtcttg ctaaagccat ctacttctgc accaccacca
    30301 aggttagagg cttgagccgc cttactagcc tgtttggcaa cacctgaagt cacattggca
    30361 aggacagtgt ttccaattgc acgggcagtg taattagcta ggaagtaagc agaaactaga
    30421 gcagggatag caatcaagat agattcggtg atgaattgac ccaagatact tgcctgcttg
    30481 aggccgatag agaggagaat tcccacttcc ttgcgacggg cgttgatcca aaggctgagc
    30541 aagagggcaa ggaggagaac tgagaagctc aagctacccc agaagaggag gttagccatc
    30601 ttgtacatac cagagataga ttgctcaaga gctgggtagt tagaggagct cttgacgagt
    30661 gtgtagctct tccagttgat accactgatg ccattcaact ctttcataac atcatccaag
    30721 ttcttgtctg ctgttacaaa gaaggttgcg tccccataaa tggctgtgtc ttctgtgtat
    30781 ccataaagtt ttgcagcagt gtgaatgtct gtaatagctg tgttttcgta aagttcttgt
    30841 gagtaggtta ctgctgactt attatgacca tcaaagagtc ccttgattgt cacttcaact
    30901 gtttccttgg ctcctttttc attatctgca tcgtagatat tagagtccag tttaaccttg
    30961 tcccctactt tccagccgtg tttggctgcc aagtccttgt gcaagaggat tttatccttg
    31021 tcgtcgttgg ttaagtgctc tccttcgact agtttataag aaccagagac aaacttgtct
    31081 tctttagagg agtcattgac acctgtaatc atcaagctac ttccaaaacg tttggcacga
    31141 tcagcagtga gattcttctt ggtttctggc gtttcaatga ggtcatatcc agtcaaatct
    31201 ccgatagcgt tgatacgttt gacataagac tcgatggcct tgttttcggt gatttttttg
    31261 atgtcttcac ccttgatatt cccagcacca cgaggcgttc cttggttgac gcgacgattg
    31321 atttgcatgg agaagctatt ggtgatattt ttaaaggtct cctgagaagc cttggcagta
    31381 gctcccttga ttgacaagcc gaccaaactc aagctcgcca tgaggagaat aatcaggaag
    31441 atgacaatcg atttgaaaaa cttccttgta acataggcaa atgcgttgtg taacatagat
    31501 tccctttcta gattttgttt taatcattct attaaaataa gctcaaatta tttactagta
    31561 ttgcgcgttt cagtcagttt cttatccttt aattcaagtg taatatctga cgcttgtgcc
    31621 acttctttac tgtgagttac gacaatcaca catttacctg ttttctgggc aagtgatttg
    31681 agtagttcga caatatctcc agcagtttta ggatccagat ttcctgttgg ctcatcagct
    31741 agaataactg gagcttctga gaccaaactg cgagcaatgg caacacgttg ctgttgacca
    31801 cctgataact ggagaacatt ccgcttgatc tggctttcat ccaaaccaag ctcaagaagt
    31861 gtatccttgc ttgccttttt gttgaccaag cggatatttt ccagcggaga aagataatct
    31921 atcaagttat aattttgaaa gaccagggaa atatggtgca tgcgatggta agaatagccc
    31981 ttcttacgaa tatcctctcc ttgaaaaagg atagaacctt caacaggact atctagacca
    32041 gcaagtaggg acaagagtgt ggattttcct gctcctgact ccccaataat actgtaaaat
    32101 tttccgggtt caaaattata atcgatctga tataggactg cttcagcagt attcttataa
    32161 cggtaggtaa catcttgtaa ttgtaataaa gtcatgattt ctccttctta actaatagat
    32221 gataaaattt ctttcggtga ttttctaaat aaaaatagga aacaaagggc tacagataag
    32281 caactaagca gaactagaaa aacataggat tctgcaaaag ataagatgct agttgataaa
    32341 ctgcttgctt tggctagtgt atcttgtaag cttgcctgat ctccacttgc tagtagagtt
    32401 tggagtaggt aagttgtgat tccgtttcct gcaacaaatg ctggaagcaa agctccaaga
    32461 gataccaaaa ctacctctaa acagaattgt aggaagatcg agctcttgcc ttttccaagt
    32521 gcaagtaaaa tccccacttc atagacccgt tctctcaacc agagagacaa aaccagaatt
    32581 aaggctccag ctcctgctat caacatccca taaaggaaga tggtcaggaa ggtttggaaa
    32641 gttgcaactg agtctttgat ttgttcaaaa gccttgtttt ccttttcgac ttggtagcct
    32701 tgattttcca aggccaagtt ttctacctgc ttcatgagtc cgtccatttc cttaggattt
    32761 tctacataga agcgtgctgc actgacttga gcttcactat tgcccaaaag ggtttggcta
    32821 ctttcatagt ctgtaaagac ttgattttca ctgaagtcag aagacaagcc tgtgaatttc
    32881 tcttgttttt taccagaaaa gatgccgata atctcaaact ctactgtttg tccttttcca
    32941 gattcagact gaccagcatc caagccaatc ttgtcatgaa gtgaaagacc gttcttctta
    33001 gccaattctt cgtggataag gattttcttg gaatcccctt tttgaaggtg tcgcccttct
    33061 tttagattga aagccgaact ggtaaaggtt acatccttgg atgaatcctc aagagccgtt
    33121 aagctaacca agttattgtc tgcagctgat aaatcatcac gctccacgct ctgctcgcca
    33181 gtcactgctt ccttgtcttt tagttttgcg accgtctcaa gttcaggaga gacattttcc
    33241 agccccttaa tcttgcttac agatgctagg tctgacaact tgaatgtctg accattctct
    33301 atcttcttaa tagaaaaaga tgtattgagt gatttataaa gattgctttc tactgttttg
    33361 ttggacttca tcagagtcaa acaggctgaa attccggcca ataagaccaa taaaatcaga
    33421 aataaaataa aacttctcag tcgctttctg ctgacataag cccaagatct ttggattgga
    33481 ttcatttgtc acctccatat ttgtaagact attataaaac ccaaatatga aatgtttatg
    33541 aaatacgaaa aaaaaatatc gagtagggga taatctctag cccctctcac accaccgtac
    33601 gtgccgttcg gcatacggcg gttcaactaa cttttaacgc atgtcgttca aggtaataat
    33661 ccaaacacga aaccagtcca cgtttttcaa ggactggttt tgatatagca cgtttaagta
    33721 ccgacttctg agctactata gtagattgaa actagaatag tacacctcta cttctaaaat
    33781 attgttagaa atcgatttga ctgtcctgat tgattcgtcc tattcttatt tcattttaat
    33841 ataattgata gtggtcgccc cagccagata ccttatctgc tatccattta ggaaccccta
    33901 acttaagcaa tccccataat cgtctcgatt tcttcttcca ttgcttccag ataatcactc
    33961 gtaggcgagt acgcaagcgc tcatctatgt tagtgactat acttttcata tttataattc
    34021 attcctttcg tttcactcaa ggcacaacac agaatgaaaa agtgttgtga tctttatttt
    34081 gttttataat aatagtgaga aagcctatca ctactacaaa tcacggggag gtgaataagt
    34141 gagtggtaca gccactacct cgcatatttt gtcacatcat ttaacggtac ataataagtt
    34201 gtaccatctg aataagttgc tacaatatca tttgcatgct ctccttcacc tttagcaaag
    34261 gttggagctc ctgctggatg atttttattt gcctctttca atttttcaat aatggcattt
    34321 ttttctgtat cttttatatt atcaggattt ttcactaaaa ttttgtctgg atatgtcggt
    34381 ttagcagaaa caatttttac tgttacttct tttttattcg aagcacttgt ccagtttcca
    34441 gcattatctt tagcatttaa ttttacagta attcctgaac taggaacttc agtagcaggt
    34501 tgattatcaa cattattcaa ctttaatttc aaaagagctg ttgcatcaga cgttttatca
    34561 atcgttgtat ataatgatga attgttatta taaccagttt cttcatattt agctgtttgt
    34621 gagctacttg agacagaact gaaattatgc ccactacctc cctgattatc ttcaatgctt
    34681 acgtctaaat gaacttcccc actattattt ggcttagcaa caactgttat agtaaaataa
    34741 cataaaattt gcataaatag attagggaaa tcaaagcaac ttctaggaat gttttagcag
    34801 tcacagtgta ctttcccagc atcaagccac tataactctg cacataaaaa tggagaagat
    34861 ggccatcctc ttctccaaat attaacttct ttacaaacca actatagttg acaaagaacc
    34921 taaaatcaat tgataacaca aggtcaggtc ggtcaactct ttcaactgaa gccctgtcaa
    34981 ctcttcccat ttatcaatct tgtattggag agaattgcgg tgcagataga gttgctgagc
    35041 tgttttagtg agaacagcac tattttccca aagagagaga atgatttcct gaatctgatc
    35101 ttgatccaaa atcatctggt gtagacattc cttgattggc ttcaagtcca cgagtctttc
    35161 tcccatactc caaagataga gctgagaaaa agtatgaaca ccttggtgac cctgacgcca
    35221 ccatgtcttg aacaaatccc gctcagcttt gattaagtct gatagggctt gatgtcccgt
    35281 ctgagaccaa acctgaccca acatgataga aagacgaagt ccaaagtcat actcaaccgc
    35341 ttcaatcgta tcacttaaaa tatctcttac agaagtgtat ttgtcttgtt gaagcacgaa
    35401 aacataatcc tgagatccga cctgtagcac tgtctgacaa ttcggaaaaa gagtccgcat
    35461 catatctagc caagaagcca gattttcctg ctgaaaataa gaaagatggc aataaaccaa
    35521 ctgaatcttt ttaaaaactt gcggtgcctg tcccttgcct tcaaccagat aggaatacca
    35581 agggtttagc gaacgagcct gctcctgctg ggtcaaaagg gcaaccaact gcttttcacg
    35641 ctcgctgagc ccagcttcct ccagcaaaat ccactgctga gaagctaaag ggagcgtgag
    35701 atagccctct ttctctactg gttggtctga aatccgagcc tcaggaaacc agtcttgtag
    35761 ttctttttcc ctcatgttct agccctccac tttttggatg caccatgaaa ccaaactctc
    35821 aagacgttcc agattctcag tcatatggag atagcccata accgcttcaa atcccgtgga
    35881 catacgataa gtcacgacat ctgcattttt agcctttgtg tggctattgg tattgcggcc
    35941 acgtttgtag atttcttctt ctttttccgt taggacctgc tcctccaaca tgagagcaat
    36001 caggcgagcc tgagccttgg ctgacacata cttggttgct tcttgatgga gtttattggg
    36061 tttggtcata cctttgagga tgaggtgacg gcgaatatac atagaataca ccgcatcccc
    36121 ctcaaaggct agcgcaatcc cgttaatgag attgacatca atcacgtgtc cacctcactc
    36181 catccttggt atcaaggagc ttaattcctt gagtaaccaa ttggtcacgg atttggtctg
    36241 ctgtctcaaa gtctcgattg gcacgcgcct cttggcgttt ttgaatcaag tcttcaatct
    36301 ctgcatccaa aacttcctca acaaagacaa ttccaaaaat ttctaacata tctgcaagag
    36361 cttgcttgac acttgcatca tagttccctg agttgatcca tttggccatt tcaaagacaa
    36421 ctgtgatacc gttggcagca ttaaaatctt catccatagc tgctacaaac ttatctttaa
    36481 agttttgtaa ctcttgggca tccacgtttc ctgtaaatgg ttgttcgtaa gtattcttca
    36541 gatacttgag attggtctcg gcatcgcgaa ctgccttttc cgtgaagttg ataggcttac
    36601 ggtagtgctg ggtcgcaaag aagaaacgaa gtacttgccc atcaagagtt ttaagggcat
    36661 cgtgtaccgt aatgaagtta cccaaggact tagacatttt gacattgtcg atattgacaa
    36721 agccattgtg catccagtag ttagcaaaag ccttgcctgt tttagcttca gactgggcaa
    36781 tttcattggt gtggtgtgga aactctaggt cagctccacc accgtggata tcaatggtat
    36841 cacctaaaat ctctgtcgac atgactgaac actcaatatg ccaacccgga cgtccaggtc
    36901 cccaaggact atcccaagaa atctcacctg gtttggaaga tttccataga gcaaagtcta
    36961 caggattttc cttacgagcc gtttcttcat cggtacgacc tgaagcacct agctccaaat
    37021 cttccaaggt tttattagcc aatttagcat agttgtggga tttttctaca cggaaataga
    37081 catccccttg actctcatag gcaaagtctt tctcgatcaa gtcttccaca aaacggatga
    37141 tgtctgccat aaactccact acacgcggat ggcgagtcgc aggtttcacg cccaaggccg
    37201 ccacatcctc acgaaaggca gcgatgtact tatccgcaac ctcctgaggc gtgatacctt
    37261 cttccctggc acggttgata atcttatcat ccacatctgt aaaattggaa atataggcaa
    37321 ccttataccc acggtactca aaatagcgac gaatcgtatc aaaagctacc gtcgaacggg
    37381 cgtttcccac gtggatatag ttgtacaccg ttggcccaca aacatacatc ttgatcttgc
    37441 cgtcctcaat cgggacaaat tcgcgcaaat cacgagacat ggtgtcatag attttaatca
    37501 taaatcataa tcaagaaagc tgaaatccaa gaacaattag tttcatcact aaaagttcaa
    37561 gtaaatttca gtccgaatat ctctacactt cggaatccct tgctcctttc tcattcagat
    37621 aaaccacctg agtctgtttg acaaagccaa ttttttcata caaacgtttg gcacctacat
    37681 tgctatcttc cactgcaatc tgaaattcct tgtcattttg ctcaattagt tggttgacga
    37741 gggattttgc taagtagctt ccatagcctt tcccacgttc aggttccgat attgctaaac
    37801 cgtagaagta attcgtatta gtcgataaat ctaccgtgca agtcccaata acctgaccgt
    37861 cttttaacaa aatatataag cgactttctg gatccttcag agcttcagcg acatatctat
    37921 ccacaacttc tctcgattca tgtccctctg aaaatgcctg aaattttaat tgactaattt
    37981 gatcctgata caaactatct gctaacaaaa tttcaagatg ggaaacattt gctaacggat
    38041 aaggtcttct atccttacct aaccaagttt ctgtctcttc atcctcgatt agtccccagt
    38101 tactggcaaa gtcaggatga ttctctaaaa aaatacgttc tgtctgaaaa gtgactgacc
    38161 gaatggggaa agaagctgtt tctctctcaa aactagtaaa caatgcacgc gcaatcccct
    38221 gacggcgatg acctggatga accagtatcg tcacttctac atcttggtca tctgcataga
    38281 cagttaataa accaacaagt ttgccttttt cataataaag gaaaaaggcg ggcatgtttg
    38341 ggtcaaaatt aagcatgtta gagagatagg gatcgcgata ggtaccgtca tagttttggc
    38401 aacagttaat tacttttttc gcctcagata gctcttcttg gcttaacttg tttcttgctt
    38461 gaatcatata ggtatcctct acaaaccaga cgatctgtga ctggcatctt tagcctgctc
    38521 gagtttattg acataatact cccgtttttc ttcgacttcg tgaatgacag gctcatcttt
    38581 cttaccatga agacggacaa tcttggccgg aataccgaca accgtcacat cactaggtac
    38641 atctgctacg acaactgctg cagcaccgac cttggcattt tcaccaattt ccacaggccc
    38701 gataacttgg gcatgggctg atatgagggc tccctttcgt acagtcggat ggcgtttgcc
    38761 acagtctttc cctgttcccc cgagagtcac tccgtgatag agaagaacgc ctttttcaac
    38821 aatcgctgtc tctccaatca ccagaccaga accatggtca ataaagacac ctgaatcaat
    38881 ctgggctcct ggatgaatct caatctgagt ccaaaagcgc caaaactgac tgtgcatacg
    38941 agctaagagt ttgaagtcgt acttccagag aaaatgcgag agacggtggg ccgccaaggc
    39001 cttgacacct ggataagtca gcaaaacctc caaagtggtg cgggccgctg gatcattttc
    39061 ttttacgata tcaatggttt cgcgccacca ccccatacat ttctcctttt cttactctga
    39121 atcttttggt gtttctgtaa attctttctt aggtttgtga tccttgtgat gacgtgggcg
    39181 gtgagggcgc tcagactttt cacctttttc atcatgctca ggttttggcg gacgaggtag
    39241 aagagccttc atagaggcat cgatacggcc tttttcatca atcttgataa ccttaacatc
    39301 aacttcatcc ccgatttcta ccaaatcctc tacacgattg gtacgagtcc aagccatctc
    39361 agagatatga acaagggcat ctgtcttatc aaagaggtta acaaaggcac caaatttctc
    39421 gatacgaacg actttagcac ggtaagcttc atccactttg gcttcacgaa ccaaaccagc
    39481 aataatttct ttggcacggt taatagcatc ttggtcacta gagtagatag acacatttcc
    39541 ttcttcgtct atatcaatct taacacctgt ttcagcgata atcttgtcga tggtttctcc
    39601 acccttaccg atgacaatct taatcttgtc cacatcaatc ttgatcgtat caattttcgg
    39661 agcagttgga gccaattcta gacgaacttc tggaatggtt gcttcaatga catcaaggat
    39721 ttcaaaacgc gctttcttgg cttgagcaag agcctccgtc aagatttctg cagtaatccc
    39781 ttgaatcttg atatccattt gaagggctgt aatcccatca cgagtacctg caaccttgaa
    39841 gtccatatct ccaaagtgat cttccaaacc ttggatatct gtcaatactg tgtagttatt
    39901 tccatctgag ataagtccca tagcaatacc agctactggc gccttgattg gcacaccacc
    39961 agccataagg gcaagagttc ccgcacagat agaagcttga gatgaagaac cgtttgattc
    40021 caaaacttct gctactagac ggatagcgta tgggaattct tccaagcttg gcaagacttg
    40081 agcaagagca cgctcaccaa gggcaccgtg accgatttca cgacgacctg gcgcaccgta
    40141 acgacctgtt tcccctacag aatattgagg gaagttatag tggtgcataa agcgtttctt
    40201 gtactctgga tccaaaccat caatgatttg agtttctccc atcggagcca aggtcaagac
    40261 tgaaagagct tgagtttgcc cacgagtaaa gagacctgaa ccatgtacac gaggaaggaa
    40321 gtcaacaacc gcatccaaag gacggatttc atcgacctta cgaccatcag gacgcacctt
    40381 gtcttctgta attaaacgtc gcacttctgc gtgttccatt tgttccaaga tttcagccac
    40441 atcacgcata atacggtcaa attcttcgtg gtccgcatat ttttcttcgt aaacggcagt
    40501 cacttggtct ttcactgctt gagttgcagc ttcacgggcc aatttctctt ctacttgaac
    40561 tgccttttgg aggtcactgt tgtaggctgc aatgatttca gcttgcaatt cagcatccac
    40621 gtgaagcaat tccacttctg ctttttcttt accgacagca gcaacgattt cttcttggaa
    40681 ggcaatcaat tctttgacag cttcgtgccc tttaaggagc gcttccaaca tgatttcttc
    40741 tgacaattct ttggcaccag actctaccat gttgatagcg tgcttggttc cagctactgt
    40801 caattcaaga agagattgct ctgcttgttc ttgacttggg ttgatgatga tttggccatc
    40861 tacatatccc acttgtaccc cagcaattgg tccgtcaaat ggaatatctg aaatagacag
    40921 tgccaaagat gaaccaaaca tagcagccat tggtgcagat gcattttcat cataagaaag
    40981 cactgtattg atgacttgga cttcattacg gaaaccttcc gcaaacatag gacgaatcgg
    41041 acggtcaatc aaacgcgctg tcaaggtcgc atctgttgaa ggacgtcctt cacgtttcat
    41101 aaagccacca ggaaacttcc cagccgcata cattttttct tcgtagttga cttggagtgg
    41161 gaagaaatcc ccagttgcca ttttcttaga cataacggca gcagtcaaga cagttgactc
    41221 accgtaacgt acgacaacag atccatttgc ttgcttagca acctgaccag tctctacaat
    41281 taactcacga cccgcaaaag tcgtttgaaa cacttgtttt gccattttaa tcccctttgg
    41341 attgatgaaa ttatacgcct tgcctacaaa gatcaagata ccaaggacgt caaaagcaaa
    41401 gtaaaaatag gaaactgacg aagtcttcga tgaagacaag acagtttatc ttttttacac
    41461 agcttttcgg ccgtgttcaa ttacacaaga tattttggac ggttcggctt gccgaacatt
    41521 tctgtagaaa aataggaagg tgacgtcgca ctcgacgagt gctaggaagc ttatcttttt
    41581 tcctaagaaa tgagaccaaa attcaattac tcaagatact aagccgtcaa gcaactcaaa
    41641 ggaaaatagg aaatcgaacg acggagcgac tgctcctagg gagatttatc tttttccaca
    41701 gagttgtagg cgagttcaat tttcaagata taaatcatta gaaaggttta atactaaagt
    41761 atctaaagct ttcacgctaa tcgctatcgg gcgattagct aaatgcttta ctaactctct
    41821 cgtcaaataa catcgatttg actcactcgt gtcgttaaat cttacagttt aaatgcattg
    41881 tattatttaa taccttcatc tttgtatcaa gtacgtacag aatctatttt atcatatttt
    41941 tcttaaaaag tgaggtcttt accattaaaa aggaaccatt cccctcacct gagaagaatg
    42001 gtttgctttt attatcctag agactggtga ttaaacaagg catgggttgc ttgatggatg
    42061 tattttgctg tatcagcatt attcatcgta tagagatgca caccggcaac atcctgagtt
    42121 accaagtcca cgatttggtc cactgcatag gcaagtcctg ctgctctgag cgactcaggg
    42181 tcatgctcat acttgtctaa gatggcttta aatttgcgtg gaagatggat attctcacaa
    42241 gtcttcaaga gtcggagagc ctgatttcga ttcagaattg gcataattcc tgcatgaatg
    42301 ggaacatcaa tcccagccaa gatacacttg tcctgaaaat catagaagcg ctcattgtca
    42361 aagaagagct gagttacgag gctcgaacag cctgcatcca ctttcttctt aagattttga
    42421 atatctgaaa tctgatttgg cgaatctgga tgcccttctg gatagcaagc tccaataata
    42481 tcaaagtgag gggcttgttc cttgataaac tcaatcaagt cggttgcata gcggaaatcc
    42541 ttttgtggtt ctacgtctgg aataatatcc ccacgaagag ccaagatttt ctgaacccca
    42601 actttgtcca agtcagcaat agtttcagca accttgtcct tagttagata aatagctggc
    42661 aagtgggcaa tggtcggaat cgccaagtca ttttggataa agtcagccaa acgaaccgtc
    42721 gtttccttga tattaaattt attattgctg gcagttacac tgataaaatg gggagccaac
    42781 tcctgcatat cctgcaaggc tgaaatactg ttaccattac ccacggctgg gtttggaggg
    42841 aacacttcaa atgagagtga cggtgtttgg cgtgacatat gtaataacct tttctagttg
    42901 atttcttttt gaacaaccac tgtatggaga gaaatccaat cttacaattt ctcacgcgca
    42961 gctttagctg cttcaacaag gcggatcaag ctttcttttg tttctgggat accacgtgtt
    43021 ttcaaaccac agtcagggtt gatccaaact ttcttgcttg gcactttagc aaggatggct
    43081 tcgattgtgt tgtcgatttc gccttcattt ggtacacgag gtgagtggat atcgtaaacc
    43141 ccaggtccca cttctgtttg gaagtttttc gctttgagtt cgtccaagat ttcaaggttt
    43201 gaacggctag cttcaaagga aataacgtct gcatccatgt tatcgatagc tgggatgata
    43261 tctgtaaatt ctgagtaaca catgtgagtg tggatttgtg tgtctggcgc tactgttgag
    43321 tgtaccaagc ggaaggcagg aatagcccag tcaaggtagt cttcgtacca gtcgctacgg
    43381 cggagtggca atttttcacg aagagcagcc tcgtcgattt ggatgatttt cacaccagca
    43441 gcttcaaggt caagtacttc atccttgata gcaagggcga tttggagagt tgaatccttg
    43501 atagagatgt cttcacgtgg gaatgaccag ttaaggatgg taacaggtcc agtcaacata
    43561 cctttaacag gtttgtttgt acgactttgt gcatagctag accatttaac agtgataggg
    43621 ttaagacgag tgacatcacc ccagatgatt ggtggtttta ccccacgcat accgtatgat
    43681 tgtacccatc catttttaga gaagaggtat cctgacaagt tttgaccgaa gtactcaacc
    43741 atgtcattac gctcaaattc accgtgaaca aggacatcaa agtcaatatc ttcttgccac
    43801 ttgatccatt cgtcaatcgt ttcagcaagg aaagcgtcgt actctttttg agacaattca
    43861 cctttacggt aagccaaacg tttggcacga acttcttttg tttgagggaa tgaaccaatc
    43921 gttgttgttg gaagagctgg aagtttgaaa gcttcttctt ggatagcttc acgttctgca
    43981 aaggctggca aacgagtgta gtctgcgtct gtcaagccag cgatacgcgc acgaagttca
    44041 gcattttcac caacacgctc agtcgcaaag agttctttgt tggctgcaag agcttctgaa
    44101 ccttgaccat tgcggatagc atccaagtca cggatttcat ccaatttttc aactgcaaag
    44161 gcaaagtggt tcaagagtgc tggttcaaat tcttcattag cagttgtaaa tggcacatga
    44221 agaagtgagc aagagcttgt caaaacgatg ttttcagctg ggatttgctc aagaacagcc
    44281 aagctctttt cgtagttgtt gcgccagatg tttttaccat tgacaatacc tgcatagaga
    44341 gtcttgtcag ctgggaagcc acctttaacg agttcaagag ttttcttacc ttcaacaaag
    44401 tcaagaccga tagcatctac tggcaagttt acaaggtcag cgtatacgtc acgaacatca
    44461 ccgaaataag tttgaaacaa gacttcaaga ccttttttgt cagccaagag tttgttgtaa
    44521 aggttcaaga agagagcttt ttcttcagct gtcaagtctt ttacaagagc cgcttcatcc
    44581 aattggatgc gagtcgcacc aaggtcagcc aatttagcaa aaacttcttg gtaagcagcc
    44641 acaaagctat ctacgaagtc gtctgctttc acgccttctt caaagtctga caattgaagg
    44701 aaagtgaatg gacctacaag aacaggacga gtgtccaatc caagttcttt tgcttcttgg
    44761 aactcatcga aaatcttgtg accagccaat tttacttgag tgtctttttc aaatttagga
    44821 acgatgtagt ggtagttagt gttgaaccat ttcttcattg gaagggcgcg aacgtcccct
    44881 ttttctccct ggtaaccacg tcccaaagcg aagtagcgct caaggtcaga caagtccaag
    44941 ttttgaacgg atgcaggcac cacgttgaaa aggaaagccg catctaggaa gttatcatag
    45001 tgagaaaagt catttgatgg aatttcagtg atgccttttt ctttgacaat gttccagtgt
    45061 ttagcacgca agtcttttgc tgctgctaaa agttcttctt ctgagatttc ttttctaaag
    45121 tatttttcag ttgtaaattt taattcacgg aattcgccca aacgagggaa accgatgatt
    45181 gtagttgaca tgatgtgtcc tccaaaattt gttgttgaaa ctatcttaac agaaaagaaa
    45241 gcgtctgtat aattgtaaaa aattagggtt tgatatagtt tgaaactata tatctgtttc
    45301 ggacaaaaga aaaagacttg aagcaaacgt ctcaaatcct ttgtatagct tgttttatag
    45361 ctttatttca gttagacggt tcaaacgcgt tattagtaat tcttataagt gactatggct
    45421 tgttattaga aaagactata actgattcta gtcaactttt tccctgttca agtcggacga
    45481 ctgctagtgt ctttcctaaa ctggctagga cttttaagac tgtatccaac tgaggactag
    45541 tctttcctgt ctccatccta gctatgacag gctggcttat tccactgact tcttccagct
    45601 ttttctgact gattccttgt tcatacctag cctcaatcaa ctcgctcatg atagccactc
    45661 gcatatcact ttcaaggatt tcctccttgc taaagagctc agatggacat ccttccaatt
    45721 actcccaata gcactattct tcatcactta accctctttc ttttacgtct atgtattttt
    45781 gaaaaaatga gcgaattatg attcgataga ctgaccagca ggtttaaaat tgggactagc
    45841 ttgtttctta agcgcttttc cttttctagg ataaagcaaa tcctgtttgc ttaaccccaa
    45901 ttttccatga tgaatccaat agtaaatggt tgaaattccc acgttaaccc ctttagccat
    45961 caccatcatt tcaggcgaaa atttttggtt atgatagtgg agaatctttt cctttagttc
    46021 cttggtcaag cttgatttct tgaccgagcg cttgcgattg ttttcataag actgttgagc
    46081 atagtcggca gaataaacct ctttgaagcg cccttttcca agacattgtc ggactgtccc
    46141 acgcttgatt tcagtgtgga tagtttgagg agcttttcca agtagagagg caatttctct
    46201 atttgatttc ccttcttttt tccatctttc gattaagcga cggctatcga ttgtcaaatg
    46261 tttggctttt gtagtataat tgtcttgcat ctctgtgcct tttaatcatt tcaatcttaa
    46321 attggacttt ttttacttgg gttgtactta atctatgagg aagacaagaa aaagaatatc
    46381 aatcaagtaa agtcacaaag tcacattagc tccgagcaac cattgcaaat tgaggtactc
    46441 acacaatgat taaaacattt ctctctgccc tttcggtcat tctcttttct atccctatca
    46501 taacttattc ttttttccca tcttctaatc ttaacatttg gctatctacc caacctatct
    46561 tggcacagat ttatgccttc cccttagcta ctgcaactat ggctgctatt ttaagtttct
    46621 tatttttttt cctatctttt tacaagaaaa ataaacaaat acggttttac tctggcattt
    46681 tgctcttact atcgctcata ttactattat tcggaacaga taaaaccctt tcttctgcat
    46741 caaataagac taaaacctta aaattagtaa cttggaacgt cgctaatcaa atagaagcac
    46801 aacatattga gcgaattttt agccattttg acgccgatat ggctatattc cctgaactag
    46861 ctaccaatat cagaggtgag caagaaaacc agagaatcaa actattgttt catcaagttg
    46921 gactttctat ggccaactat gatattttca cttctccacc taccaatagt ggaatagctc
    46981 ctgtgactgt gattgtcaag aaaagttatg gtttctatac agaagctaaa acttttcata
    47041 caacacggtt cgggacaatt gtattacatt cgagaaaaca aaatatacca gatatcattg
    47101 ccttgcatac tgctcctcct ctgccaggtt taatggaaat ctggaagcaa gacttaaaca
    47161 tcattcataa tcaattggct tcaaaatatc caaaggctat tattgcaggt gattttaatg
    47221 caactatgcg tcatggagca cttgcaaaaa taagctctca tagggacgca ttaaatgtac
    47281 tgccaccttt tgaaagagga acttggaata gccaaagtcc aaaacttttt aatgcaacaa
    47341 tagatcatat tttattgcct aaaaaccact actatgttaa agatttagac attgtaagtt
    47401 ttcaaaactc tgatcataga tgtattttta cagaaatcac attttaatta ttttatataa
    47461 aatcacccct ctagtgttca taaactagag ggggaatttg tatcatacta tcgtttaacg
    47521 cacttctgca ttcacttttt cttcgagcga tgcttggatt ttttccatat agcgtgcgac
    47581 ttcttcgtcc gttaagctat cttctggatt ttggaaggtc aagctataag ccattgactt
    47641 cataccaagt cccaatttct cacctgagaa gacgtcaaag agtttgatat ctgtcaaacg
    47701 tttcacgccg gcagcttgga tagcatctac aacttcttga tgagtcactt ctgccttgag
    47761 gagaagggca acgtcacggc tgactgccgg gaatttggtg atttctacaa atggagtcgc
    47821 tggctgaagc gcagcttcga tagctgaaag gttaagctca gctacatacg tttctggaat
    47881 atcgtaagcc ttggcagtga ctggatgcac ttggccaagg aaaccaagaa cttggtcacc
    47941 gagtgaaatc acggctgtac gacctggatg aaggctagcg atttcagatg ttgctgtata
    48001 ggttacttgg agtcccaaac gagtaaatag ggcttcaagg attcccttag catagaagaa
    48061 atcaactgga actgctgctg tttggaaatc tttttcagca accaagcctg tcaaggcaaa
    48121 ggcaaagctg ttgatctcat ttggaagttc ttcttttgga ttacctgttt gttcaaagac
    48181 ttttccaatc tcataaaggg caaagttttt attcttacga gccacgttgt aggcaacggt
    48241 atcaaggatc cctgaaatca tattttgacg gaggactgaa cgatccacag tcattggcca
    48301 catgagttca gtaaggttac tcggttgagc tgtgaactca actgcttttt caggagttgt
    48361 cagagcatag gtgatgattt ctgtcaaacc tactccttca gcaatggtac gaacttgacg
    48421 gcggagtttt tgtgtcacag tcaattcacc agctgtacca tcgtcttttg gaaggctggt
    48481 tggcaagcgg tcatatccat agatacgagc gatttcttca aagagatcag cttcgattgt
    48541 gatatcccaa cgacgacgtg gtacgctgac tgtaaagctg tctgcatttc cagaaagacc
    48601 aaagccaaga cgacggaaga cgtcttctac atcagcataa gacagctcag ttccgaggac
    48661 acggttaaca tcagcaaggg ttgaagaaac ttccacatca gaggtatcaa gctcacccgc
    48721 tgaaacgata cccttacgca ccgtcgcgcc tgcaagctct gcaatcatgc tagctgccgc
    48781 atcaagggct tcattaactg ttgccacatt aattcctttt tcaaagcgag aagatgactc
    48841 agaacgaagg ttcaggcgac cacttgtctt acggatagat ttgccattaa aaatagcagc
    48901 ttcaaggata acacgactag atttttcaga aatttctgta gcctgaccac ccataacacc
    48961 ggcaagggct actggtttgt cagcaactgt aatcacgagg tctgtctcag ccaagtctcg
    49021 ttcttcaccg tccagggtca ctaatttttc accatcacgc gcttcacgca cacggatgtc
    49081 agtcccttca aagttatcca agtcaaaggc atgcattggt tgaccaaaat agagcaggat
    49141 gtagttggtc acgtccacta cgttattgat gggacggatg ccttcgttca tgagaaggtt
    49201 ttgcaaccat tgtggacttg gtgcgatggt cacattgtcc aagatacgag ctgcatagta
    49261 aggcgccttg tctgtcccaa tgctgacaga aagggcatct gccgcagatt cattagtttc
    49321 tgttagagta aattctttaa agttgactgc cttgtcatag atggctgcca cttcgtgagc
    49381 cactccacac atagaaaggg catctgcacg gtttggtgtg atggaaagtt cgatgatttc
    49441 atcatccaag tctaggtaag aaaagacttc ctcacctggc acggcatttt ctggcaagat
    49501 ttggatgcca tctgcgaatt ccttaggcac aactgagtca gaaattccca attcaccaag
    49561 tgaacagatc attccaagtg actccaaacc acggattttt ccttttttga ttttgtagtt
    49621 atcagcaata cgagctcctg gaagagccac catgaccttg atcccagcac gcacatttgg
    49681 ggcaccacaa acgatctgac gggcttcttc ttcgccaacg ttaacctgac aaacatggag
    49741 gtgagtctct ggcacatctt cgcaagacaa gacctcaccg acaacaattt ttgagagatc
    49801 agcagctggt gattcgacac tctctacctc gatccctgtg gttgacattt tttcagccaa
    49861 ctcctgtgat ggcacatcaa tgtccaccaa ttcttttaac catttataag atacaagcat
    49921 aatttagttc tccagaatga ccattgccac actggttctt ttcctttcct atcatttcaa
    49981 tagaagaatt ctcttcttac cttaatttct ttctcagtaa ccaatccgta tctacttttt
    50041 gaccaaccat aaaatgatgt tggctaaatt tttcaaaacc atatcggtta taaaacgctt
    50101 gagcttttgt attatgctcc caaacaccta gccaagccca agaaaaacta ttttttgtag
    50161 caagttcaag tgcgaattca aacagttgct tacctagtcc aaatccttgg aatttttgta
    50221 gcacatagag gcgttgaatt tcaaaagcgt cctctaattc tctctcagtt tgagcacttc
    50281 cccagttgac tttgagaaaa ccagctatct cctcctcatg cataatgaaa taggtttcag
    50341 agtcaggatt tcccaactca gttgacaaag ttttcagact ataagcctct tcaaagtatt
    50401 cctgtaactg ctcttccgta ttatcatacg caaaggtttc acgaaaggct tgtttggcaa
    50461 ttttagccaa cacctcaaca tctgccattt ctacttttct aatcattatt taaactgttc
    50521 tgagaagcgg acatctcctt ggtagaatcc acggatatcg ttgattccat aacggagcat
    50581 agctacacgc tcttgtccaa gaccaaaggc aaagccagag tatacagtcg catcgatacc
    50641 actcatttca aggacacgtg ggtgaaccat accggccccc ataatttcga tccaacctgt
    50701 tttcttacat acattacagc cttctccacc acacttgaag caagaaacat ccacctcaac
    50761 agatggctct gtgaatggga agtaagatgg acgcaaacga atttgacgct cttcaccaaa
    50821 cattttttgg acaatcaact gaagcgttcc ttgaagatca gccatagaga tatttttccc
    50881 aactaccaag ccttcgattt ggtggaattg gtgactgtgg gtcgcatcgt ccgtatcgcg
    50941 acggaagaca cgccctggcg agatcatctt caaaggacct ttagaaaaat catgggcatc
    51001 catagcacgc gcctgaactg gagacgtgtg ggtacggagc aagatttctt cagtgatata
    51061 gaaagtatcc tgcatatcac gagctgggtg gtcttttgga aggttcatac gttcaaagtt
    51121 atagtagtct tgctccactt caaaaccatc cacgacttga taacccatac cgatgaagat
    51181 atcttcgatt tcttcactgg tttgtgtcaa aacgtgacgg tgaccagtcg caactggacg
    51241 acctggaagc gtcacatcga tactctcgct agccagttga gccgcgactt tcttttcttc
    51301 caagagctta gctgtttctt caaaagcagc tgtcaagaca tcacgagctt cattgacgtg
    51361 tttcccgatg attggacgca tctcagcaga aacatctttc atccctttga ggatttcagt
    51421 gagcgaaccc tttttaccaa ggacagagac acgcaaatct tgcatctctt tttcatttcc
    51481 agcagtaatc tgcttcaagc tagtcagcgt ttcttcgcga agcgctttta attgttcttc
    51541 aatagttgac atatttcctc catcagtctc tcgtagataa aaagaaaacc acatgccaaa
    51601 aactccactc ggagcgttga cacgcggtac catccgtttt catctgacaa gtcagacctt
    51661 catttctaaa tccatgcgca agtgaattca cccagctttc atatagagaa cttgcagtca
    51721 cggctctcct ccctgatata cttcccttgg gctactagtc tttcagattc ctattcaatt
    51781 actacttagt ttatcagatt tttaccattc ttgcaagacc tatcttactt ctgcttgtta
    51841 gcttattctt atctaacttt atagc
//
LOCUS       DBERPV010000012        51555 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.12, whole genome shotgun sequence.
ACCESSION   DBERPV010000012 DBERPV010000000
VERSION     DBERPV010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 51555)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51555)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51555
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.12"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            633..1910
                     /gene="ltrA"
                     /locus_tag="ACL8C7_000930"
     CDS             633..1910
                     /gene="ltrA"
                     /locus_tag="ACL8C7_000930"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HGS1395162.1"
                     /translation="MSKLLDKILSRDNMLEAYNQVKSNKGSAGIDGMTIEEMDGYLRQ
                     NWRLTKELIKQRKYKPQPVLRVEIPKPNGGIRQLGIPTVMDRMIQQAIVQVISPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAASKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKFKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSLGNMK
                     SIVASIDERLRTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGWGDHYQLVAQK
                     SVLKRAISKPVLEKRGLVSCLDYYLERHALKVS"
     gene            2366..3544
                     /locus_tag="ACL8C7_000931"
     CDS             2366..3544
                     /locus_tag="ACL8C7_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ryptide export MFS transporter"
                     /protein_id="HGS1395163.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTCINLVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            3858..3989
                     /locus_tag="ACL8C7_000932"
     CDS             3858..3989
                     /locus_tag="ACL8C7_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HGS1395164.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            4010..5560
                     /gene="dltA"
                     /locus_tag="ACL8C7_000933"
     CDS             4010..5560
                     /gene="dltA"
                     /locus_tag="ACL8C7_000933"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HGS1395165.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGVTHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQSLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            5557..6801
                     /gene="dltB"
                     /locus_tag="ACL8C7_000934"
     CDS             5557..6801
                     /gene="dltB"
                     /locus_tag="ACL8C7_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HGS1395166.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMRGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            6815..7054
                     /gene="dltC"
                     /locus_tag="ACL8C7_000935"
     CDS             6815..7054
                     /gene="dltC"
                     /locus_tag="ACL8C7_000935"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HGS1395167.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVIEFGRDDWNTANKIIAGIVELQNA"
     gene            7047..8315
                     /gene="dltD"
                     /locus_tag="ACL8C7_000936"
     CDS             7047..8315
                     /gene="dltD"
                     /locus_tag="ACL8C7_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HGS1395168.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            8470..8910
                     /gene="adcR"
                     /locus_tag="ACL8C7_000937"
     CDS             8470..8910
                     /gene="adcR"
                     /locus_tag="ACL8C7_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HGS1395169.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            8910..9614
                     /locus_tag="ACL8C7_000938"
     CDS             8910..9614
                     /locus_tag="ACL8C7_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGS1395170.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            9607..10413
                     /locus_tag="ACL8C7_000939"
     CDS             9607..10413
                     /locus_tag="ACL8C7_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HGS1395171.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            10423..11928
                     /gene="adcA"
                     /locus_tag="ACL8C7_000940"
     CDS             10423..11928
                     /gene="adcA"
                     /locus_tag="ACL8C7_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HGS1395172.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGKEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISIMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(13056..13829)
                     /locus_tag="ACL8C7_000941"
     CDS             complement(13056..13829)
                     /locus_tag="ACL8C7_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGS1395173.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCVYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTLPDQKLLDAVELFDGEWVSDIQ"
     gene            14005..15408
                     /locus_tag="ACL8C7_000942"
     CDS             14005..15408
                     /locus_tag="ACL8C7_000942"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase family protein"
                     /protein_id="HGS1395174.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGEITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            15523..16161
                     /locus_tag="ACL8C7_000943"
     CDS             15523..16161
                     /locus_tag="ACL8C7_000943"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HGS1395175.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK"
     gene            16173..16613
                     /locus_tag="ACL8C7_000944"
     CDS             16173..16613
                     /locus_tag="ACL8C7_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HGS1395176.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            16606..17037
                     /locus_tag="ACL8C7_000945"
     CDS             16606..17037
                     /locus_tag="ACL8C7_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGS1395177.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVHNAQNSLFNVKQQLNVEEEEDLCL"
     gene            17028..17498
                     /locus_tag="ACL8C7_000946"
     CDS             17028..17498
                     /locus_tag="ACL8C7_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS1395178.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            17523..18296
                     /locus_tag="ACL8C7_000947"
     CDS             17523..18296
                     /locus_tag="ACL8C7_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGS1395179.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            18293..19093
                     /locus_tag="ACL8C7_000948"
     CDS             18293..19093
                     /locus_tag="ACL8C7_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGS1395180.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            19152..21445
                     /locus_tag="ACL8C7_000949"
                     /pseudo
     CDS             19152..21445
                     /locus_tag="ACL8C7_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase N-terminal domain-containing
                     protein"
     gene            21455..24571
                     /locus_tag="ACL8C7_000950"
     CDS             21455..24571
                     /locus_tag="ACL8C7_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 98 C-terminal
                     domain-containing protein"
                     /protein_id="HGS1395181.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGKYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYDHHSVTHTKGNSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            24628..26394
                     /locus_tag="ACL8C7_000951"
     CDS             24628..26394
                     /locus_tag="ACL8C7_000951"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008736 - L-fucose isomerase activity
                     [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0019317 - fucose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HGS1395182.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEVAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEASDTAIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRIDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVVKMFMIGRDLTQGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPVVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGCAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELDESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            26540..27691
                     /locus_tag="ACL8C7_000952"
     CDS             26540..27691
                     /locus_tag="ACL8C7_000952"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HGS1395183.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKVLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVANGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            27835..28719
                     /locus_tag="ACL8C7_000953"
     CDS             27835..28719
                     /locus_tag="ACL8C7_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGS1395184.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            29073..29324
                     /locus_tag="ACL8C7_000954"
     CDS             29073..29324
                     /locus_tag="ACL8C7_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HGS1395185.1"
                     /translation="MKEFQFERKQRFSLRPYAIGACSVLLGTSLFFAGMGDQPVQDTE
                     TSSALILSHYLDEQDLSEKLKSELQWLELENKLLNLWEH"
     gene            29312..29602
                     /locus_tag="ACL8C7_000955"
                     /pseudo
     CDS             29312..29602
                     /locus_tag="ACL8C7_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
     gene            complement(29829..29912)
                     /locus_tag="ACL8C7_000956"
                     /pseudo
     CDS             complement(29829..29912)
                     /locus_tag="ACL8C7_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(30006..31337)
                     /locus_tag="ACL8C7_000957"
     CDS             complement(30006..31337)
                     /locus_tag="ACL8C7_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HGS1395186.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNDLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(31359..32870)
                     /locus_tag="ACL8C7_000958"
     CDS             complement(31359..32870)
                     /locus_tag="ACL8C7_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HGS1395187.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            complement(33081..34028)
                     /gene="arcC"
                     /locus_tag="ACL8C7_000959"
     CDS             complement(33081..34028)
                     /gene="arcC"
                     /locus_tag="ACL8C7_000959"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HGS1395188.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIILTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            complement(34193..35209)
                     /gene="argF"
                     /locus_tag="ACL8C7_000960"
     CDS             complement(34193..35209)
                     /gene="argF"
                     /locus_tag="ACL8C7_000960"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HGS1395189.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            complement(35267..36496)
                     /gene="arcA"
                     /locus_tag="ACL8C7_000961"
     CDS             complement(35267..36496)
                     /gene="arcA"
                     /locus_tag="ACL8C7_000961"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HGS1395190.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            37251..38930
                     /locus_tag="ACL8C7_000962"
     CDS             37251..38930
                     /locus_tag="ACL8C7_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HGS1395191.1"
                     /translation="MKKIKPHRPLPSQTQLAYLGDELAAFIHFGPNTFYNQEWGTGQE
                     DPERFNPTQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPAYG
                     NGGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGNCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNLDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLAFQAGETEKSLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            complement(38970..41054)
                     /locus_tag="ACL8C7_000963"
     CDS             complement(38970..41054)
                     /locus_tag="ACL8C7_000963"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HGS1395192.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEGGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKASAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAT
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            41226..42506
                     /locus_tag="ACL8C7_000964"
     CDS             41226..42506
                     /locus_tag="ACL8C7_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HGS1395193.1"
                     /translation="MVYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            42597..45242
                     /locus_tag="ACL8C7_000965"
     CDS             42597..45242
                     /locus_tag="ACL8C7_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HGS1395194.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFELFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVQLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTACYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAYRRAKALQTSFTSLQLARQEGS
                     VVAIGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            45326..46195
                     /locus_tag="ACL8C7_000966"
     CDS             45326..46195
                     /locus_tag="ACL8C7_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGS1395195.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLTWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLTQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            46189..48069
                     /locus_tag="ACL8C7_000967"
     CDS             46189..48069
                     /locus_tag="ACL8C7_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HGS1395196.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIQGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEFYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            48395..48721
                     /locus_tag="ACL8C7_000968"
                     /pseudo
     CDS             48395..48721
                     /locus_tag="ACL8C7_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(48773..49614)
                     /locus_tag="ACL8C7_000969"
                     /pseudo
     CDS             complement(48773..49614)
                     /locus_tag="ACL8C7_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(49603..49752)
                     /locus_tag="ACL8C7_000970"
                     /pseudo
     CDS             complement(49603..49752)
                     /locus_tag="ACL8C7_000970"
                     /inference="COORDINATES: protein motif:HMM:NF016232.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            50087..>51555
                     /gene="pcpA"
                     /locus_tag="ACL8C7_000971"
     CDS             50087..>51555
                     /gene="pcpA"
                     /locus_tag="ACL8C7_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HGS1395197.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKGLWYYLNESGSMATGWVKDKG"
BASE COUNT        15805 a         9208 c        11132 g        15410 t
ORIGIN      
        1 taaaacggtc tggggataga ccgttttaag tctgacgctg gaaataagaa tcgtcagagg
       61 aagggatagc gaaatcgtgg ctctacgaat aggaacgtga taataaggcg tatatagcgg
      121 ataaggggcc tcaaactcta aagttcaaaa aggtagtcgt agcctatatg tgtaaatcac
      181 gagagtaatt gaattcggac taaggtctat gtgaaaaaga taaatcttcc tagagtctaa
      241 agactctgcg tcagatttcc tattttcatt gtaacctttt aacgtcctca tatcttgtat
      301 aaacgaggaa agatgtacga cttatcccgt gaggtttcat gagcgctgaa agcgtagtaa
      361 caacgaatca tgagaagtca gccgagccca tagtagtgag gaaacttctg tagtggaagt
      421 ggagcgaagg ggtgaatact caaacagtct ggggagagac tgtttgaggt ctgtcgctag
      481 aaagagaaaa cgacagatcg aagtaatcct acttcacttg tgtctgtaaa acgaacggtc
      541 tgatagaact ggactctgtc acgtattgac tagatgaagg ttcaccaata taagatgtcc
      601 ctcaggcacc aaaacaagaa aggaataggc acatgtcaaa attgctagat aagatattat
      661 cacgcgacaa tatgcttgaa gcctacaatc aagtaaaatc taataaaggc tcagctggga
      721 ttgatggaat gactatcgaa gagatggatg gctatctcag acaaaactgg cgcctgacta
      781 aggaactgat aaaacagaga aaatataagc ctcaaccagt tcttagagtt gagattccca
      841 aaccaaacgg aggcatccgc caactaggaa ttccaacagt tatggataga atgattcaac
      901 aggccattgt tcaagttatt agccctattt gtgaacccca tttctcagat acgagctatg
      961 gattcagacc aaataggtca tgtgaaaaag ccatcatgaa gctcttagag tacttaaatg
     1021 acggctatga gtggatagtg gacatagacc tagagaaatt tttcgataca gttcctcaag
     1081 atagattgat gtccttagta cataacatta tcgaagacgg agatacggaa tccttgattc
     1141 gtaagtatct tcattcaggt gttatcatta atggtcaacg ttataaaaca ctagttggta
     1201 caccacaggg aggaaattta tctcctctct tatccaatat catgcttaat gaattggaca
     1261 aggaattaga aaagagggga cttcgatttg tgcgctacgc agatgattgt gtgattacgg
     1321 tcggaagcga ggcagcctct aagcgtgtga tgtattcagt cagtcgtttt attgagaaac
     1381 ggctaggttt gaaagtaaac atgaccaaga ctaagattac cagaccaaga gagttgaaat
     1441 atctaggttt tgggttctgg aaatcatcag atggttggaa aagccgtcca catcaagata
     1501 gtgttcggag atttaagttt aaattgaaga aactaacaca gaggaaatgg agtatagacc
     1561 taacaagacg tattgagcaa ctgaatttgt ctattcgagg atggataaac tatttctcat
     1621 tgggaaatat gaaaagtata gtcgccagca tagatgagcg cttgcgtact cgcctacgag
     1681 tgattatctg gaagcaatgg aagaagaaat cgagacgatt atggggattg cttaagttag
     1741 gagttcctaa atggatagca gataaggtat ctggctgggg cgaccattat caattagtag
     1801 ctcagaagtc ggtacttaaa cgtgctatat caaaaccagt cctggaaaaa cgtggactgg
     1861 tttcgtgttt ggattattac cttgaacgac atgcgttaaa agttagttga accgccgtat
     1921 gccgaacggc acgtacggtg gtgtgagagg ggctagagat tatcccctac tcgattaact
     1981 cccctgaaat ttattttaat tatgcaaatt tcacgtattt ttgatgctga gacgacgatc
     2041 ctgggaactt ttcagatatt tttttgacta tctaaatcta tcattagaaa agcttagagc
     2101 gccaaaggat ttgagcgttt ttctgatttt taagactttt tccagtctct ttttcgattg
     2161 aagatgtaat tattctacta actaactaac ttcttagtac tagccaacaa cgataatcat
     2221 aattcctcct aaaattagga ataataaagg caatagtttt tgttttttca tgtaaaaaac
     2281 ctcacttttg ttttctgcta ttttatgcta aaatattaaa aatcaaattt aattccaaag
     2341 tttgtaacta aagggggagc gctacatgtc taattcattt gtcaagttgt tagtctctca
     2401 attatttgca aatttagcag atattttctt tagagtaaca atcattgcta acatatacat
     2461 tatttcaaaa tcagtaattg ccacatcact agttcctatc ttaataggaa tatcctcttt
     2521 tgttgcgagt cttttagttc cgttggttac taaaaggtta gcgctaaata gggttttatc
     2581 tttatctcaa tttggaaaga ctatattatt ggcgatactg gtaggaatgt ttaccgtaat
     2641 gcaatccgta gcgcctttgg tgacctatct atttgttgtt gcaatttcca tactagatgg
     2701 ttttgcagca cccgtttcct atgctattgt gccacgctat gcgaccgatt tgggtaaggc
     2761 taattcagcc ttatcaatga ctggtgaagc tgttcaattg ataggttggg gattaggtgg
     2821 actcttgttt gcaacaattg gtctgttacc taccacgtgt atcaatttag tcttgtatat
     2881 catttctagc tttctgatgt tatttcttcc taacgctgaa gtggaggtgt tagagtcaga
     2941 aactaatctt gaaattttgc tcaaaggttg gaagttagtt gctagaaatc ctagattaag
     3001 actttttgta tcagcaaatt tattggaaat tttttcaaat acgatttggg tttcttccat
     3061 tatacttgtt tttgtaacgg agttattaaa taaaacggaa agttactggg gatattctaa
     3121 tacagcatac tctattggta ttataattag tggcttaatt gcttttaggc tatctgaaaa
     3181 gttccttgct gctaaatggg aaagtattct ttttcctctt gtagctatgg caatagtgac
     3241 actgactatt ctatattttc caaacgcaca gatgttttta ttattttcag ctttagttgg
     3301 tatgttatcg caactaaaag aagttcctga aagtgtattt cttcaggaaa cagtagagga
     3361 aaatcattta gttaatgtct attccgttct tgaagtgatt tctacattag cattttcagt
     3421 atttgttttg ctaatgagct atattactga gagttttggt attagcatca gtttttggct
     3481 atcagccatt tgtctgatga tagaagctat tttaatttat atcagacgag attattttaa
     3541 atgagagagt ggttaaaaag tctttaaaaa tcagaaaagc gcatagtatc aggtgttgaa
     3601 aaaacttgat attgtgtgtt ttattatggg aagatttact tcattgtctc ctgaaatgga
     3661 gttttgaagc aggatcactc tatttgaaaa tatacataga aaaactgtat aatccttaaa
     3721 ataagctgaa atctattgga aacatacggt aaacaattga aaaggtacta tataaagtgg
     3781 tacaatggta gaaaaataag ctagtaagaa tcactcttat tttagcgaaa aattacagaa
     3841 atgaatggtt tttcttgatg aaacagagaa aagaattgta cctctttctt ggtcggacag
     3901 ccttgtattt tcttatcttt ctagggctgc tttacttctt tagctatctt ggtcagggtc
     3961 aaggaagctt tatctataat gaattttaac ttgaaggaga atccctattg tgtcaaataa
     4021 accaatagca gatatgattg aaaccattga gcattttgct cagacacagc ctagctatcc
     4081 tgtctataat gttttggggc aggaacacac ttatggcgat ttaaaggctg attcggatag
     4141 tttggctgca gtcattgacc aactaggctt gcctgagaag tctcctgtgg ttgtttttgg
     4201 tggccaagaa tatgaaatgt tggcaacctt tgtagcgctg actaagtcag gtcatgccta
     4261 cattccaatt gatagccatt cggccttgga gcgagtttca gctattttag aagtagcaga
     4321 gccaagtttg attattgcca tttcagcctt tcccttggag caggtttcta caccaatgat
     4381 aaatctagct caggttcaag aagcctttgc ccaagggaac aactatgaaa tcacgcatcc
     4441 agtcaaggga gatgataatt actacattat ctttacttct ggtacgactg gtaagcctaa
     4501 gggagtgcag atttcacatg ataatctcct cagctttaca aactggatga ttacggataa
     4561 ggaatttgcg acaccgagtc gtccgcaaat gctggcacag ccaccttatt cttttgactt
     4621 gtctgtcatg tattgggcac cgaccttggc acttggtggt acgcttttca ctcttccttc
     4681 agtcatcact caggacttca agcaactctt tgcggctatc ttttcattac caatcgctat
     4741 ctggacatca acaccatcct ttgcagatat ggccatgttg tctgaatact tcaacagtga
     4801 gaaaatgcct ggagtcacgc atttctactt tgatggtgaa gaattgacgg tcaaaacagc
     4861 tcaaaaactg cgcgagcgtt tcccaaatgc ccgtatcatc aatgcttacg gcccaacaga
     4921 agcgacagta gctctctcag cagttgccgt gacagacgag atgttagcga ctctcaaacg
     4981 cctaccaatc ggctatacca aggctgattc tccaaccttt atcattgacg aggaaggaaa
     5041 taaactgcca aatggcgaac agggagaaat cattgtttct gggccagctg tttcaaaagg
     5101 ttatatgaac aatcctgaaa aaacagcaga agccttcttt gagtttgaag gtctgccagc
     5161 ctatcacaca ggcgatgtgg gaaccatgac agatgagggc ttgcttctct acggcggacg
     5221 catggacttc cagattaagt ttaacggtta ccgcattgag ttagaagatg tctctcaaag
     5281 cctcaacaag tctcgcttta tcgaatctgc tgtcgcagta ccgcgctata acaaggacca
     5341 caaggtacaa aatctattgg cttatgtcat cttaaaagac ggtgttcgtg agcagtttga
     5401 gcgagatatc gatattacca aggccatcaa ggaagacctg acagacatca tgatgtccta
     5461 catgatgcca tctaaattcc tttaccgaga cagtttgcca ctaactccaa atggaaagat
     5521 tgacatcaaa ggattgatta acgaggtgaa taagagatga tggagttttt tcaacagctt
     5581 cctcatttag agccatatgg caatcctcag tattttgttt atgtgattgc tgcaaccttg
     5641 cccatcttta taggcctctt tttcaagaaa cgctttgcct ggtatgaagt gttggtaagt
     5701 ctcttcttta ttgtcaccat gttggtgggt ggaaagacca atcaactagc tgccttgggt
     5761 atttaccttt gctgggaaat attgctcctg cttttctaca agcattatcg aaaaagcaag
     5821 gatggcaagt gggtcttcta cttagttagt tttctgtccc tacttccgat tatctttgtc
     5881 aaggtgcaac cagctatcaa tggaacgcag tctttgcttg ggttcttggg aatttcttac
     5941 ctgacctttc gttcggttgg gattatcatc gagctgagag atggagtgat taaggatttt
     6001 accctctggg aattcctccg tttccttctc ttcatgccaa ctttctcgag tggtccaatc
     6061 gatcgcttta agcgatttaa tgaaaattat caggccattc ctgagcgaga tgagttgatg
     6121 gatatgctgg atgaatctgt ccgctatatc atgcggggct ttttgtataa gtttatccta
     6181 gctcatgttt taggagagac cttactacct cctctgaaga atttagcctt gcagtcaggt
     6241 ggcttcttta atctttatgc cttggcagtt atgtatactt ttggtctgga gctcttcttt
     6301 gactttgcag gttattctat gtttgctttg gccatctcaa acttgatggg aatccgtagc
     6361 cctatcaact ttaacaagcc ctttttatca agggatttaa aggagttttg gaatcgctgg
     6421 catatgagtc tgtccttctg gttccgtgac tttgtcttta tgcgaatggt gatggtgtta
     6481 accagaaaga aagtctttaa aaatcgtaat gtaacctcaa gcatggccta cattgtaaat
     6541 atgctgatta tgggattttg gcatggcgtg acctggtact atatcgccta tggactcttt
     6601 catggattag gcttggtcat caatgatgcc tgggttcgca agaaaaaaac gctcaataag
     6661 gaacggaaaa aagcagggaa ggctgcccta cctgagaatc gctggattca gttgcttggt
     6721 atggttgtca ctttccatgt tgtcatgttg tcattcttaa tcttttctgg attcttgaat
     6781 aatctatggt ttaaaaaata aaaggaaata aaatatggat atcaaatcag aagttatcga
     6841 aattattgat gagttgttta tggaagatgt ttctgacatg atggatgaag atctttttga
     6901 tgcaggtgtc ttggatagta tgggaacggt tgagttgatt gtggagattg agaaccgttt
     6961 tgacattcgt gtccctgtaa tagagtttgg tcgtgacgac tggaatacag ctaataaaat
     7021 catagctggt attgtggagc tacaaaatgc ttaaacgctt atggatgatc ttcggaccgg
     7081 tcttgatcgc tggtttgttg gtttttctgc tcattttctt ttatcctact gagatgcatc
     7141 ataatctagg agctgaaaag cgttcagcgg tggctactac tatcgatagt tttaaggagc
     7201 gaagtcaaaa agtcagagca ctatctgatc caaatgtgcg ttttgttccc ttctttggct
     7261 ctagtgaatg gcttcgtttt gacggtgctc atcctgcggt attagctgag aaatacaatc
     7321 gttcctaccg tccttatctt ttaggacagg ggggagctgc atcgcttaac caatattttg
     7381 gaatgcaaca gatgttacca cagctggaga ataaacaagt tgtgtatgtt atctcacctc
     7441 agtggttcag taaaaatggc tatgatccag cagccttcca gcagtatttt aatggagacc
     7501 agttgactag ttttctgaaa catcaatctg gggatcaggc tagtcaatat gcagcgactc
     7561 gcttactgca acagttccca aacgtagcta tgaaggacct ggttcagaag ttggcaagta
     7621 aagaagaatt gtcgacagca gataatgaaa tgattgaatt attggctcgt tttaatgaac
     7681 gccaagcctc cttttttggt cagttttcgg ttagaggcta tgttaactac gataagcatg
     7741 tagctaagta tttaaaaatc ttgccagacc agttttctta tcaagcaata gaagatgttg
     7801 tcaaagcaga tgctgaaaaa aatacttcca ataatgagat gggaatggaa aattatttct
     7861 ataatgagca gatcaagaag gatttgaaga aattaaagga ttctcagaaa agctttacct
     7921 atctcaagtc gccagagtat aatgacttgc agttggtttt aacacagttt tctaaatcta
     7981 aggtaaaccc gatttttatc attccacctg ttaataaaaa atggatggac tatgctggtc
     8041 tacgagagga tatgtaccaa caaacggtgc agaagattcg ctaccagtta gaaagtcaag
     8101 gttttaccaa tatagcagat ttttctaagg acggcgggga gcctttcttt atgaaggaca
     8161 ccattcacct tggttggttg ggttggttgg cttttgacaa ggcagttgat cctttcctat
     8221 ccaatcccac accagctccg acttaccatc tgaatgagcg ctttttcagc aaagattggg
     8281 cgacttatga tggagatgtc aaagaatttc aatagataat ataatataga agagttcaag
     8341 aatgaaacta gttttcacgt tttttcttga ctcttttttt gcttgtgata taattaactg
     8401 gtaaacaaaa tgtcaaagaa tagtattttt ctcttaaaaa agagaagtct aaaaggaaag
     8461 gagtcagata tgagacagct agcaaaggat atcaatgctt ttttgaatga ggtgattttg
     8521 caggcggaaa atcagcatga aatcctaata ggtcattgca ctagcgaggt ggccctgacc
     8581 aatactcagg agcatatcct tatgctcttg tcagaggaat ctttaacaaa ttcagaattg
     8641 gcccgtcgtc tcaatgtcag tcaggcggca gttaccaagg ccattaagtc tttggtcaag
     8701 gaagggatgt tggaaacatc taaagattct aaagatgcgc gtgtgatttt ttatcagttg
     8761 actgacttgg ctcgtccaat cgctgaggag caccaccatc accatgagca tacactttta
     8821 acctatgaac aagtggcgac tcagtttact ccaaatgaac aaaaagtgat tcagcggttt
     8881 ttgactgctt tagtaggaga aatcaaataa tgagatatat tacggtagag gatttgtcct
     8941 tctattatga taaggagcct gttcttgaac atatcaatta ttgtgttgat agtggggaat
     9001 ttgttacctt gactggggaa aatggagcgg ctaagacgac gctcatcaag gctagtcttg
     9061 gaattctgca accacgcatt ggaaaggtgg ctatttcaaa gacaaatacg caaggtaaga
     9121 aattgagaat agcctatctt cctcaacaaa ttgccagttt taatgctggt tttccaagta
     9181 cggtctatga atttgtcaag tcgggtcgct atccgagaaa aggctggttc cgtcgtttga
     9241 atgctcatga tgaggagcat atcaaggcta gtctggactc agttggcatg tgggaacatc
     9301 gagacaaacg cttggggtct ctatctgggg gacaaaagca gcgagcggta attgcgcgta
     9361 tgtttgcttc tgaccctgat gtgtttatcc tagacgagcc gacaacgggg atggatgcag
     9421 gaagtaaaaa tgaattttac gaactcatgc accatagcgc ccatcatcat ggcaaggctg
     9481 ttttgatgat tacccatgac cctgaagaag ttaaggatta tgcggatcgc aatattcatc
     9541 tagtccgtaa ccaagactcg ccatggcgtt gtttcaacgt tcatgagaat ggccaggagg
     9601 tgggccatgc ttagtttatt atcttacgac tttatacaac gcgccttttt ggcggttatt
     9661 gctatgagtc ttttctcacc ggtattggga accttcctca tcttgcgtcg tcagagtttg
     9721 atgagtgata cccttagcca cgtctcactt tcaggtgtag cctttggtct ggttttgggg
     9781 atttctccaa ctgtttctac tattgccatt gtcttgattg cggcggtctt tctggagtat
     9841 ctccgtacag tttacaagag ctttatggaa atcgggacag ctatcctcat gtcaacaggt
     9901 ctggctgttt ctctgattgt catgagcaag ggtaaaagct cgagttcaat gagtttggac
     9961 caatatctct ttggttcgat cgtgactatc agtgaagaac aggtcatttc cctctttgtc
    10021 attgcggcgg ttgttttgat tttgaccttt ctctttcttc gtcctatgta tatcttaact
    10081 tttgacgaag atacggcctt tgtggatggc ttgccagttc gtaccatgtc cattcttttt
    10141 aacatggtga caggggtggc tattgccctt atgattcctg cagcaggagc tcttctagta
    10201 tcgaccatta tggtcttgcc agctagtatt gccctgcgtc tggggaaaaa ctttaaatcg
    10261 gttatgctgc ttgccagtgc gattggcttt ttgggaatgg tagcaggact ttacatttcc
    10321 tactatgcag aaacacctgc aagtgcaagt attaccatta tttttgtaac tgtctttata
    10381 ctaatcagtt tagtaagacg ttttatcaaa taggagacga acgtgaaaaa aattagctta
    10441 ttactagcca gtctatgtgc cttgttttta gtggcttgtt ccaatcaaaa acaggcagat
    10501 ggtaaactca atatcgtgac aaccttttac cctgtctatg aatttaccaa gcaagtcgca
    10561 ggagatacgg ctaatgtaga actcctaatc ggtgctggga cagaacctca tgaatacgaa
    10621 ccatctgcca aggcagttgc caaaatccaa gatgcagata ccttcgttta tgaaaatgaa
    10681 aacatggaaa catgggtacc taaattgcta gataccttgg ataagaaaaa agtgaaaacc
    10741 atcaaggcga caggcgatat gttgctcttg ccaggtggca aggaagaaga gggagaccat
    10801 gaccatggag aagaaggtca tcaccatgag tttgaccccc atgtttggtt atcaccagtt
    10861 cgtgccatta aactagtaga gcacatccgc gacagcttgt cagcagatta tcctgataaa
    10921 aaagagacct ttgagaagaa tgcagctgcc tatatcgaaa aattgcaagc cttggataag
    10981 gcttacgcag aaggcttgtc tcaagcaaaa caaaagagct ttgtgactca acacgcagcc
    11041 tttaactatc ttgccttgga ctatggactc aaacaagtcg caatctcagg actttctcca
    11101 gatgcagagc catcagctgc tcgcttggca gaattgacag agtatgtcaa gaaaaataaa
    11161 atcgcctata tctattttga agaaaatgcc tcacaagccc ttgctaacac actttcaaaa
    11221 gaagcaggtg tcaaaactga tgtcctcaat cctttagaaa gtctgacaga agaggacacc
    11281 aaggctggag aaaattacat ctctatcatg gagaaaaacc tcaaggcttt gaaacaaaca
    11341 acagaccaag aaggcccagc gatcgagcct gaaaaggcag aggataccaa gacagtccaa
    11401 aatggttact tcgaggatgc agctgtcaag gaccgcacct tgagtgacta tgcaggtaac
    11461 tggcaatcag tttatccttt ccttgaagac ggcacgtttg accaagtctt tgactacaag
    11521 gctaagttga ctggtaagat gacccaggct gagtacaagg cttattatac aaaaggctat
    11581 cagacagatg tgactaagat taacattact gataatacta tggaatttgt tcaaggtgga
    11641 caaagcaaga aatatactta caagtatgtc ggtaagaaaa ttttgactta caagaaaggc
    11701 aatcgtggcg tgcgtttcct ctttgaagcc acagatgctg acgctggaca attcaagtat
    11761 gttcagttta gtgaccacaa tgttgcccca gttaaggcag aacatttcca tatctttttt
    11821 ggaggtacaa gccaagaagc tctatttgaa gaaatggata attggccaac ctactaccca
    11881 gataacctat ctggccaaga aatcgctcaa gaaatgttgg cgcattaatg agaaatcgac
    11941 tagttcataa gagctagtcg gtttttgggt actagatggc taacttcatt atagactttt
    12001 cagaactaag gaactttaaa aaaataaata aaactcttga aatatctgga cttatatgct
    12061 agaatgtagt tagtgtataa ggttcattag aacaccaaag cccctaacta gtgccatagt
    12121 taagggcttt tttgatgtat cttagcgatt taacgggtgt ttataggcta gtcagtcggt
    12181 ctacttctta ccatctagcc atttgcagac gaaatacaag ataattccag ctataacatc
    12241 tgctataata gtaagagcaa gctctggtat aaggctcatt agtttcacct cctctcacga
    12301 acccatagga acgtaatcgg taaccgatga caaaagtatt atatcacact aaatttagat
    12361 catcaacctc acttaatgct tgaactattg tagattatat gctaaaatgt agttaattga
    12421 taaggttcat tagaacacca aagcccctaa ctatggccgt agttaagggc ttttttgacg
    12481 tatcttagcg atttaatggg tgtttatagg ctagtcagtc ggtctactcc ttactatcta
    12541 gccatctgca gacgaaatac aagataattc cagctataac atccgctata atagtaagag
    12601 cgagctctat gataaggctc attagtttca cctcctctca cgaacccata ggaacgtaat
    12661 cggtaaccga tgacaaaaat agtataccac aatacattta gatcatcaag gtcacttaat
    12721 tcttgaaata tcagatctaa gagaaaaatc tttaaaatca gaaaaacgca taatatcagg
    12781 tgtgcaaaaa cttgatacta tgcgttttat tgtgggaagg tttactccat tttctcctga
    12841 aattgagttt ttgtccagcc tctgttttta gggttgctaa gaaaataatg tcatgtggtg
    12901 aatatttgta aatcagtcag cagacagaac gaatactctt cgaaaatctc ttcacatcat
    12961 gtcagcttcg tcttgccgtg tccatggggg acttgacttc atcagttttc aaatctgtac
    13021 tgtgagcaag ttgagactag cttcctattt gattttcatt gaatatcaga aacccattct
    13081 ccatcaaata attcgactgc gtctaataat ttttgatctg gcaaggtgtc agaaataaag
    13141 gttgtgtatt tggagagggg attaatttta aaaaatccag tcttgtaaaa tttagaacta
    13201 tcaatcagta agatggtttc atgggctttg tcaataatat tcttttttga aatagcttgg
    13261 ctgagagaag cttcataaac atattggtca tcaatacctc ttgctgaaca aaatgctaaa
    13321 tcgatattaa aatgatctaa taaagaattt tccttatcat agttgaccac ggaacaggat
    13381 tgatgtttga cctcgccaga tgtgataaag attttggagc tatctttaac agtttcagat
    13441 agggtttgtg cagtatgtaa accatttgta aaaataatca aattatcaag ttcagaaaga
    13501 tagggacaaa gttcgtagac agtcgtactg gaatccagat aaacacacat accagaccga
    13561 ataaagtctt tagcgagact agcgattagt cttttttgcc tagtactttc tccttcccgt
    13621 atttgatgag aaagttcaat tgtgttcata gaggacaggg tcacgtatcc gtgctttctt
    13681 ttgataagac cttgattttc taagaaaatt aaatcacgac gtaaggtact tgtgctggag
    13741 aaagtgattt ctgccagctc ttttacggca attctttttt tctttttgat aatttcaatc
    13801 aattcaagta cacgttcatc ttttatcata agctcctcct aatttatcat ttcaactata
    13861 ttatagcaca aattggagga atttgaatta tttttatgaa tattgggtta acatttgaac
    13921 attattcaag taagcgttca catattgaaa aaataaaatg tggggattat aataaagtta
    13981 atcaaggacg aagagagaag aaaaatggaa gcggttttag caatagattt aggtgcgact
    14041 tctggaagag caatcgttgg ttacctttct gaaaataaac tagtaatgga agaaataaat
    14101 cgcttttcta atctacctat tagagtaaaa gggcatttat cttgggatat tgactttcta
    14161 ctagctaaaa ttcttgaaag tatccgcttg gctaatacta gttacaagat tttatctatc
    14221 ggtattgaca catggggagt tgattttgga ctgattgata atgaaggtaa gctgttatca
    14281 caacctgttc attatcgtga tgaaagaaca aagggagtgt taaaggaaat atctgaaatg
    14341 actgaattag aaaaactgta ttcagagaca ggaaatcaga ttatggagat aaataccttg
    14401 tttcaactct ttaaggcacg tcaagaatct cctgactctt tctataagac caataagatt
    14461 cttttaatgc cagatttgtt taattatctc ttgacaggta agtttgctac agaaaaaagc
    14521 attgcttcaa caactcaatt atttgatcct aggagtcaaa attggaatca gaatatctta
    14581 aaactatttg aattggattc atctttactt cctgaaattg tttcagaggg aaatgttctt
    14641 ggaaggataa aaaaggagta tggtttaggc gatattcctg ttgtgaatgt ttgtagtcat
    14701 gatacagcaa gtgcgattgt ctcagtacct aagacagaag gtagtttatt tatttcatca
    14761 ggtacttggt ctttggttgg agtggaactt acttcaccga ttcttactac cgaatccttc
    14821 agttatggat ttacaaatga agtcggtaaa gatggagaga ttacatttct gaagaattgt
    14881 acagggttgt ggatcataga ggaactaaga cgttcatttg aacgaagagg gaaagcctat
    14941 tcttttgatg atattaggac aatggtggag aaagaaaaag aaaatcttcc tctgattgat
    15001 actgaatcaa ctgaatttgc aacagaatct gatatgcaca agactttgac agaatatcta
    15061 gcttatcatc atgaaactag agagtggaca gatggacaac tatttaagat tgtttatgaa
    15121 agcctagctg aaacgtatag gaaagcgata gagttattag aagaactaac tcataaggtt
    15181 tataagagga tatatgtgat tggaggaggt gctagagcca gttactttaa ccaaatgatt
    15241 gctgatagaa ctggtaaaga ggttcttaca ggttcgactg agggtacagc tgtggggaat
    15301 attgttgtgc agctcatagc tatgggacaa ttaaaaggga tggaagaagc tcaccatgtt
    15361 attgaggagt tcctacaatt agagagttat tactcccaaa agaattaaaa agattgagag
    15421 tttgtaaatt tgcctccctc ccccttctta gcttttgtgc aggaaggggg gataattggt
    15481 gaattgaaaa atatttagtg ttttgatatg aggaggacaa ggatgtcaga tgtaaaacaa
    15541 gaattaatta aatatggtaa gaagctagta gaaacagatt tgacgaaagg aacaggtggg
    15601 aatctcagcg ttttcgatcg tgaaaaacaa ttgatggcaa ttaccccgtc gggtattgat
    15661 ttctttgaaa tcaaagaatc cgatattgta gtgatggata ttaatggaaa tgttgtagag
    15721 ggagaacgct tgccatctag cgaatggtat atgcatttga ttcaatatca aactcgtgat
    15781 gatatcgatg caattatcca tgctcataca acttatgcaa cagtattagc ttgtctcaga
    15841 gaaccacttc cagcgagtca ttatatgatt gcagtggcag ggaaagatgt tcgggtagct
    15901 gagtatgcaa catatggtac gaaagaattg gctgtgaatg cagctaaagc aatggaaggt
    15961 cgtagagcag ttttactagc gaatcatgga attttagcag gtgcacaaaa tttattgaat
    16021 gcatttaata ttgttgaaga agttgaatat tgtgcaaaaa tttattgttt agctaagaat
    16081 tttggagagc cagtagttct tcctgatgag gagatggaat tgatggcaga aaaatttaaa
    16141 acatacggtc agagaaaata gggaggatat taatgttaaa acatataccg aaaaatattt
    16201 ctccagattt attgaagact ttaatggaaa tgggacatgg agatgaaata gtattagctg
    16261 acgcgaatta tccttctgcc tcatgtgcaa ataagctaat tcgttgtgat ggtgtaaata
    16321 ttccagaatt attagattcc attctgtatt taatgccatt agatagttac gtcgatagtt
    16381 caattcagtt tatgaacgtt gtttcgggtg atgatattcc taagatatgg ggtacctata
    16441 gacaaatgat tgaaggtcat ggtacagatc ttaaaacgat tacttatctt agaagagaag
    16501 acttttatga acgtagtaag aaagcttatg ctattgttgc tacaggagaa acttcacttt
    16561 atgctaatat tatccttaag aaaggagtag ttgttgaaag agaaaatgtt taatagagga
    16621 attttagttg ccagtcatgg taattttgct agcggagctc tcatgaccgc agaaatgttt
    16681 gttggtgaga caacaaatga tagagttagg acattaggtt tgatgcctgg agagaatatt
    16741 gtagagtttg aacattattt taaaaatcaa gtaaatgaac tgttagactc aaatcaagag
    16801 gttatcgttt tgactgactt gattggagga agtcctaata atgtggcttt gtcacggttt
    16861 ttaaatttgg attcagttga tattgtaaca gggtttaata tccctctcct agtggaatta
    16921 atatcaagtt atgattcaaa aatcaattta gaagaaattg ttcacaatgc tcaaaatagt
    16981 ttgtttaatg ttaaacaaca acttaacgta gaggaggaag aggatttatg tctatagagt
    17041 ttgttcgtat tgatgaccgt ctggtacatg gtcaagttgt cactacgtgg ctaaaaaagt
    17101 atgatattga gcaagttatc attgttaatg atcgcatctc agaagataaa acacgacaat
    17161 ctattttaaa gatttctgca ccggtaggtt taaaaattgt tttctttagt gtaaaacggt
    17221 ttgtggaagt tttaaactct gtgccaataa aaaagagaac aatgctgata tatacaaatc
    17281 caaaagatgt gtatgattct attgaaggaa atttaaaatt ggagtacctc aatgtaggac
    17341 agatgagtaa aacggaggaa aatgaaaagg taacgggagg tgtagctcta ggtgaagaag
    17401 acaaatatta ttttaagaaa atagttgata agggaacgag agttgaaatt caaatggttc
    17461 ctaatgataa agttacaatg ttggaaaaat ttttataaaa ataatttaag gaggtacagt
    17521 atatgctatt cacacaagca ttactggtga cattagttgg gattattgcc actattgact
    17581 ataatggacc gttatttatg attcaccgtc cgttagttac aagtgcaatg gttggcttag
    17641 tcttaggaga tttcacccaa ggtgttctta ttggttcagc tcttgaatta acttggctcg
    17701 gtgtaacagg tattggaggt tacactccac cagatactat ttcaggtgcg attattggta
    17761 ctgcatttgg tattttgtct ggtcaaggag aaactgctgg tatcgctata gcagttccaa
    17821 ttgcagttgc tactcaacag ttggatgttc ttgcaaaaac tttagatgtt tattttgtga
    17881 aaaaagctga taatgatgct aaaaacggag attattcaaa gatcggtttt tatcattatt
    17941 caagtttggt tttaatcact ttatttaaaa ttgtaccaat tttcctagct attatgcttg
    18001 gaggggaata tgtggcagac ttgtttgcta aggttccacc aatcgttatg cagggactta
    18061 actctgcagg tgctttacta ccttcaattg gttttggtat gcttttaaat atgatgctca
    18121 agaaaaatat gtgggtattc ttgttgattg gattcatttg ttctgtgtat ggaggaatgt
    18181 caaccattgg gatctcacta gttggtattg cggtagcata cttctacgat atgattggaa
    18241 gtaaaccaca agaaacaact tcaagtagtg atgttgagga ggatcttgat ctatgatgaa
    18301 taataaagta actaaagttg aacttaaaaa agttttcaaa cgaagtttta tgtatggttc
    18361 ttcatggaac tatgagagaa tgcagaacct aggttttcta tatacaattc ttccagtatt
    18421 gaaaaaacta tacccagaca aagattcagc ttctcctgca atgaaacgtc accttgagtt
    18481 tttcaatact catcaaacag cggcaccatt tattcttgga gttacttccg ctatggaaga
    18541 acaagaagga aatgaaggtg cagcttcaat tactggtatt aaagttggct tgatggggcc
    18601 actggctggt ctaggagata gtttgttctg gctgacacta gttcctatct gttttagtat
    18661 tggtgcgtct tattctaaag acggcggtgc tttaggtatc tttatcgcct taatattgtt
    18721 taatattatt aatattcctg ttaaatattt cggtttgaaa tatgggtata ctaagggttc
    18781 tagtcttatc caagaaaata atacaaaagg aacattgaat cgcgttacga gtatggcgac
    18841 agcattaggg ctagtactag tgggtggttt gattccatca atggttggta ttaattttgg
    18901 attagaattt aagcaggggg aacttgttat ttctgttcaa gaaatgatta caaaattaat
    18961 tccaggattt atccctatgg ctttgacttt attaatgtgt aaattaatta gaaaaggaaa
    19021 gaatccggtt gtactaatct ttagtgttat ggctattgga gttatcctag ttgttttagg
    19081 aattttgaag tagtagaaag tgtggaggtg gtatttggga tatcacctcc attttggaag
    19141 agaggtaaag agtgaaatta tggtataaga aagctgccgc aaattggaat gaagccttgc
    19201 cgattgggaa cggtcattta ggtggtatga tttatggttc agctacaaaa gaatgtattc
    19261 aactaaacga tgagactatt tggtatagag gaaagtcaga tagaaataat ccagactcac
    19321 tattgcatct taaaaaaatt cgggaatatc ttttagatgg agaaattcag aaagccgaag
    19381 aattgataaa gttaacaatg tttgctaccc caagagatca aagccactat gaattacttg
    19441 gggaactttg cattgagcat atagatattc agtcttgtgc tctttcattg tatgaaagag
    19501 agctagattt agatacagct atttctaatg ttgtgtttga gcctaatagt tgtaatttac
    19561 aaataaaaag agaatatttt acgagtttta ataagaatat tttatgttgc cgtatagtgt
    19621 catcagttca aaacacatta aatttaaaca ttaatttggg tagaaataaa cggtttaatg
    19681 acgaagtatc taaactggat tcaagtacaa ttttaatgtc ggcctctgct ggaggtagaa
    19741 aaggtgttca gtttaaagta gtatgtcatt ctaaggttac ggatggtgaa gtaagtgtat
    19801 tgggagagac aatagttatt cggaatgcta cagaggtatt tctttatctc aaatcaatga
    19861 cggattattg gggaaatata gatatttctt ctcttcaggg agaatttagt agtattgatt
    19921 actttacaga aaaagatgaa catgtaaaaa atatcaggag caatttaata gagttgattt
    19981 taaactagac tatagtaaag gttgtcttag cattccaacg aatctacttc ttgaaaacac
    20041 taaaaagtat agtaactact tgactaactt gttatttcat tatggaagat atctgttaat
    20101 atcgtctagt caaccgaatg gtttacctgc caatcttcaa ggaatatggt gtgatgaatt
    20161 aaatccaatt tggggttcta aatatacgat taatattaat actcaaatga attattggat
    20221 ggtaggtcca tgtgatttac cagaagtaga atatccatta tttgatatgc tcgaaagaat
    20281 gagagaaccg ggaagactaa ccgctaagaa aatgtatgga gctagaggtt ttacagcaca
    20341 tcataatacg gatggttttg gcgatacggc tccccaatct catgccatgg gggctgcaat
    20401 ttgggtatta actattccat ggttatgtac tcatatttgg gaacactatt tatatttcca
    20461 agatgagcgt attcttacgg aacattttga aatgataaaa gaagcatttc ttttctttga
    20521 agattattta tttgaggtgg atggctactt gatgacaggt ccaagtgtct caccggaaaa
    20581 taaatatcgc ttaaaaaatg gtattgaagg aaatgcttgt ctatcatcta caattgataa
    20641 tcaaatttta agatattttt gtgattcatg cattggaatt gcaaaacaat taggagacaa
    20701 ttcggatttt attagtcgtg tgaaggagtt aaaaaagaaa ttacctagaa caaaaatagg
    20761 tagtaatggg caaatacaag aatggctaga ggattatgaa gaagtagagc ctggtcatag
    20821 acacatttca cctctatttg ggctttatcc ttataatgag attgatattc ataaaactcc
    20881 ggaattagca gaagcagcta aaatcactat caataggaga ttatcaaacg ctaacttttt
    20941 atcttcacag gatagggagc aagcgattaa taattggtta gtaagtggtt tgcatgctag
    21001 tacacaaaca ggttggagtg ctgcatggct gattcatttt tttgcgagac tatatcaagg
    21061 tgaacctgct tataaccaga ttaatggttt gttaaataat gcgactcttg gcaatttatt
    21121 tcttgaccat ccaccatttc aaattgatgg taatttaggt ttggtgagtg gaatttgtga
    21181 attattagta cagagccatc ataattggtt atcactaatt ccagctttac cttctgcttg
    21241 gtcagaagga gaagtgaaag gtttcagagt aagaggagga tataaggtat cgtttgcttg
    21301 gaaaaatggg gatataacat tcctaaaatt ggaaggagga aacaaagatc aaaaagtaag
    21361 agtaagaata tatggcaaaa atactgatgt acaaaatatt gaattggtat ttaattcaga
    21421 aaaaattatt gagttaaatt tttaggtata agtcatgaat aaagaaaaaa taaaaagaaa
    21481 attaatcaca atactgtttg tatgtattgg gatgttatgt tttggattgt tagcaggagt
    21541 taaggctgat aatcgtgttc aaatgagaac gacgattaat aatgaatcgc cattgttgct
    21601 ttctccgttg tatggcaatg ataatggtaa cggattatgg tgggggaaca cattgaaggg
    21661 agcatgggaa gctattcctg aagatgtaaa gccatatgca gcgattgaac ttcatcctgc
    21721 aaaagtctgt aaaccaacaa gttgtattcc acgagatacg aaagaattga gagaatggta
    21781 tgtcaagatg ttggaggaag ctcaaagtct aaacattcca gttttcttgg ttattatgtc
    21841 ggctggagag cgtaatacag ttcctccaga gtggttagat gaacaattcc aaaagtatag
    21901 tgtgttaaaa ggtgttttaa atattgagaa ttattggatt tacaataacc agttagctcc
    21961 gcatagtgct aaatatttgg aagtttgtgc caaatatgga gcgcatttta tctggcatga
    22021 tcatgaaaaa tggttctggg aaactattat gaatgatccg acattctttg aagcgagtca
    22081 aaaatatcat aaaaatttgg tgttggcaac taaaaatacg ccaataagag atgatgcggg
    22141 tacagattct atcgttagtg gattttggtt gagtggctta tgtgataact ggggctcatc
    22201 aacagataca tggaaatggt gggaaaaaca ttatacaaac acatttgaaa ctggaagagc
    22261 tagggatatg agatcctatg catcggaacc agaatcaatg attgctatgg aaatgatgaa
    22321 tgtatatact gggggaggca cagtttataa ttttgaatgt gccgcgtata catttatgac
    22381 aaatgatgta ccaactccag catttactaa aggtattatt cctttcttta gacatgctat
    22441 acaaaatcca gctccaagta aggaagaagt tgtaaataga acaaaagctg tattttggaa
    22501 tggagaaggt aggattagtt cattaaacgg attttatcaa ggactttatt cgaatgatga
    22561 aacaatgcct ttatataata atgggaaata tcatattctt cctgtaatac atgagaaaat
    22621 tgataaggaa aagatttcat ctatattccc taatgcaaaa attttgacta aaaatagtga
    22681 ggaattgtct agtaaagtca actatttaaa ctcgctttat ccaaaacttt atgaaggaga
    22741 tgggtatgct cagcgtgtag gtaattcctg gtatatttat aatagtaatg ctaatatcaa
    22801 taaaaatcag caagtaatgt tgcctatgta tactaataat acaaagtcgt tatcgttaga
    22861 tttgacgcca catacttacg ctgttgttaa agaaaatcca aataatttac atattttatt
    22921 gaacaattac aggacagata agacagctat gtgggcatta tcaggaaatt ttgatgcatc
    22981 aaaaagttgg aagaaagaag aattagagtt agcgaactgg ataagcaaaa attattccat
    23041 caatcctgta gataatgact ttaggacaac aacacttaca ttaaaagggc atactggtca
    23101 taaacctcag ataaatataa gtggcgataa aaatcattat acttatacag aaaattggga
    23161 tgagaatacc catgtttata ccattacggt taatcataat ggaatggtag agatgtctat
    23221 aaatactgaa gggacaggcc cagtcccttt cccaacacca gataaattta atgatggtaa
    23281 tttgaatata gcatatgcaa aaccaacaac acaaagttct gtagattaca atggagaccc
    23341 taatagagct gtggatggta acagaaatgg taattttaac tctggttcgg taacacacac
    23401 tagggcagat aatccctctt ggtgggaagt cgatttgaaa aaaatggata aagttgggct
    23461 tgttaaaatt tataatcgca cagatgctga gactcaacgt ctatctaatt ttgatgtgat
    23521 tctatatgac aataatagaa acgaagttgc taagaaacat gttaataatt tgtcgggtga
    23581 atctgttagt ctagatttca aagaaaaagg agcaaggtat attaaagtta aattactaac
    23641 gagtggagtg cctttgagtt tagcagaagt agaggttttt agagaatcag atggtaagca
    23701 atctgaagag gatatagata aaataacaga agataaagta gtctctacaa ataaggtagc
    23761 tactcaaagt tcaaccaatt atgagggtgt agctgcttta gcagttgatg gtaataaaga
    23821 tggagattac ggacatcatt cggtgactca tactaaggca gattctaacg cttggtggca
    23881 ggtcgatctg ggagaagagt ttacggtttc taaagttgat atttataata gaacagatgc
    23941 cgaacctcag cgtttatcta attttgatgt tatttttcta tcttcatcag gagaagaagt
    24001 ttttagaaga cattttgata aagtagttga tggtttgtta tctttaaaag taccttctgt
    24061 aggggctaag ctagtcaaaa tagaattaaa atcagcagct attccgttaa gtttagcgga
    24121 agttgaagtc tatggttcaa agagaactcc gaagaaactt tctaatattg cattaaccaa
    24181 agaaactcga cagagttcaa cggattacaa tggtttttct cgtctagcag ttgatggaaa
    24241 taaaaacgga gattatgatc atcattcagt gactcatacc aaaggaaatt ctccttcatg
    24301 gtgggagata gatttagcac aaaccgaaga attagaaaag ttaattattt ataatagaac
    24361 agatgctgaa attcagagat tatcaaattt tgatattatt atatatgatt caaataatca
    24421 tgaagttttt aaacaacata ttgacagttt agaaagcaat aatctatcca tagacttaaa
    24481 agggctgaag ggaaaaaagg ttagaatttc tttgagaaac gcaggaattc ctttaagttt
    24541 ggcagaggta gaggtttata cttataagta attttaaaaa ttatcatcgg tagtatgaaa
    24601 gaaacagaaa aataagagga aaatagtatg attcaacatc cacgtattgg gattcgtccg
    24661 actattgatg gtcgtcgtca aggtgtacgc gaatcacttg aagtacaaac aatgaacatg
    24721 gctaaaagtg tggcagattt gatttcaagc acattgaaat atccagatgg ggaacctgtg
    24781 gaatgtgtga tttctccatc taccattggt cgtgttccag aggttgcagc ttcccatgag
    24841 ttgtttaaaa aatcaaatgt ttgcgcaaca attacagtta caccatgctg gtgttatggt
    24901 agtgaaacta tggatatgtc tccagatatt cctcatgcta tttggggatt taatgggaca
    24961 gaacgcccag gagctgtcta tcttgcagct gtactagctt cacatgctca aaaagggatt
    25021 ccagcctttg ggatttatgg tagagacgtc caggaagcta gtgatacagc tattccagaa
    25081 gatgtcaaag aaaaactttt acgctatgcg cgtgcagctc ttgcaactgg cttgatgaga
    25141 gacactgctt acctatcaat gggtagtgtt tcgatgggga ttggtggttc tattgtaaat
    25201 ccagatttct tccaagaata cttaggaatg cgaaatgaat cggtagatat gacggagttc
    25261 acgcgccgta ttgaccgtgg tatttatgac ccagaagagt tcgaacgtgc tatggtttgg
    25321 gtaaaagaac atatcaaaga aggtgttgac cgaaatcgtg aagatttgat tctttctaaa
    25381 gaagaaaaag aaaaacaatg ggaatttgtt gtaaaaatgt tcatgattgg tcgagatctt
    25441 acgcagggaa atcctcgttt agcagagctt ggttttgagg aagaagcagt tggtcaccat
    25501 gctttagtag ctggtttcca aggtcaacgt cagtggacag accattttcc aaatggagat
    25561 tttatggaaa ctttcctcaa tactcagttt gactggaatg gtattcgaaa accagttgta
    25621 tttgcgacag agaatgattc actaaatggt gtgtctatgc tctttaatta tctattaaca
    25681 aatactccac aaatctttgc tgatgtgcgt acttattgga gtccagaggc tgttaaacgt
    25741 gtaacgggac atactttaga gggttgtgct gcagctggct tcttacatct aatcaactct
    25801 ggttcttgta cattggatgg tacaggtcaa gctactcgag atggcaaacc tgttatgaaa
    25861 ccattctggg agttggatga aagtgaagtg caggctatgc ttgaaaatac agacttccca
    25921 ccagcaaacc gcgaatactt ccgtggagga ggattctcaa ctcgtttctt gacgaagggg
    25981 gatatgccag taacaatggt acgtctcaat cttctaaaag gggttggtcc agtgctacaa
    26041 attgcagaag gttatacact tgaacttcct gaagatgttc accatacttt agataatcgt
    26101 acagatccag gatggccaac tacttggttt gctccacgtt tgacaggaaa aggtgctttc
    26161 aagtctgtct atgacgtcat gaataattgg ggagctaatc acggagccat aacatatgga
    26221 cacattggag cagacttgat taccttggct tctatgttga gaattcctgt caatatgcat
    26281 aatgtacctg aggaagatat ctttagacct aaaaattggt ccttatttgg aacagaagat
    26341 ctagaatcag cagactatcg tgcatgtcag ttgttgggac cactacataa ataaaacttg
    26401 tttatatagg aggtgaactt acgtccctcc tatcctttta aaaagatttg ttaaacaatt
    26461 cacaaataat taaaaacgaa tacaaaaagt aatataatga tgttaaataa atagcgcaaa
    26521 ggcgcaggag gaaaattata tggctacatt ttatgttccg gcagttaacc ttattggtaa
    26581 aggtgttgta aatgaagtgg gtccttatat caaggaactt ggctataaaa aggcactttt
    26641 ggtgacagat aagtacatcg aaggcagtga cattttacct aaggttttaa aaccactaga
    26701 tacagaagga atcgaatatg tcatctttag cgatgtagag ccaaacccta cttgtaagaa
    26761 tgtcacggat ggggtagctg ctttgcaaga acatggctgt gactttatca tcagtcttgg
    26821 cgggggttct ccacaggatg cagctagttg tatttctatc atggctacaa atggtggaaa
    26881 accacaggat tatgaagggc ttcataagtc tgctaaaaaa ggcttgccag ttgtggctat
    26941 caatacaacg gcaggtacat cagcagaaat taccattaac tatgtgatta ctgatgaaga
    27001 acgcaaggtt aagatggtaa tggttgacaa gaatagcctt gctcttatct ctgttaatga
    27061 ccctgaactc atgctttcca aacctaaagg cctgactgct gctactggta tggatgctct
    27121 gactcacgct gttgaagctt tggtaacacc tggtgcttat gatgtaacca agaaactgtc
    27181 tattggtgct attgagctta tcaaggaata tcttcctcgt gctgtagcaa acggacatga
    27241 tattgaagcg cgtgaaggta tggtcaatgc catcttcctt ggtggtatga gctttaataa
    27301 tgctggtctt ggctatgttc actcaatggc tcaccaactc ggtgcagtat ataatttgcc
    27361 acatggtgtt tgctgtgcca tgttgctacc agttatagaa cgtgaaaatg ctaaacgtgt
    27421 accagaagct ttccgcaatg ttgccaaagc cttgggactt catgtagaag gtaaatcaga
    27481 tcaagaatgt gccgattatg cgattgctga gattgagaag ctttctgaga cagtaggtat
    27541 tcctaagaaa ctgactgaac ttggtattga agaaaaagat ttcgactttg aatacctttc
    27601 taagaatgcc ttgattgatg cctgcgcacc aggaaatcca tttatgccaa ccttagaaga
    27661 aacgattgcc ttttataaag agttatttta gcaaggatta gacgacaata ggacaattca
    27721 cctctaatta ttgacatttc aggaaaaatc gcagtaaaaa cggcacagcc ttctttaaat
    27781 gtgctataat actagaaaaa tacttgtgga ggttccatta tggcaatatt tttcatgatt
    27841 tttctgattg tttgtgtgct cctattggtg atagtcacac tgagtacagt ttatgtggtt
    27901 cgtcagcagt cggtggcgat tattgaacgc tttgggaaat accaaaaggt tgctaatagc
    27961 ggtattcata ttcgcttgcc ttttgggatt gactcgattg cagcacggat tcagttgcgc
    28021 ttgttgcaaa gtgatattgt ggttgagact aagaccaagg acaatgtgtt cgttatgatg
    28081 aatgtagcga ctcagtaccg tgtcaacgag cagagcgtga cagatgctta ctataaactc
    28141 atacgtccag aatctcagat taaatcttat atcgaagatg ctcttcgctc ttctgttcca
    28201 aaattaacct tggatgaatt gtttgagaaa aaagatgaga ttgcccttga ggttcaacac
    28261 caagtagcag aagaaatgac cacttacggt tacattatcg tgaaaacctt gattaccaag
    28321 gtcgaaccag atgcagaagt taagcaatcc atgaatgaaa tcaatgcggc gcaacgtaag
    28381 cgggtcgcag cacaagaatt ggcggaagct gacaagatta aaattgtcac tgcagctgaa
    28441 gcagaagcag aaaaagaccg ccttcatggt gtggggattg cccaacaacg taaggcgatt
    28501 gtggatggat tggcagagtc tatcaccgaa ctcaaggaag ccaatgttgg catgacagaa
    28561 gaacaaatca tgtctatcct cttgaccaac cagtatttgg ataccttgaa tacctttgcc
    28621 tctaaaggaa atcaaaccat ctttttacca aatactccaa atggtgtgga tgatatccga
    28681 acacaaatct tgtcagccct tcgcgctgag aagaaataat agactaatac tcttcgaaaa
    28741 tctcttcaaa ccacgtcagc gtcgccttgc cgtatagatg ttactgactt cgtcagttct
    28801 atctgcaacc tcaaaacagt gttttgagca acctgtggct agtttcctag tttgctcttt
    28861 gattttcatt gagtataaag agcttggcaa caggctcttt ttgtattgcg tttattaaga
    28921 aaaacaaaaa acatcgatat acatttaact aaaaattatt gtatgttatc tctcttaatt
    28981 aggaatgata agggaataac tagaaagatt tgtgaataca aactatttct gatatacaaa
    29041 atatacagta ataatgaatg atgggagatg ggatgaaaga atttcaattt gagagaaagc
    29101 agcgtttttc tttgaggcca tatgcaatag gagcttgttc ggtcttgcta ggaacgagtt
    29161 tattttttgc tggtatgggt gatcagcctg tacaggatac agaaacgagt tcagcactaa
    29221 ttttaagtca ttatttggat gagcaggatt tatctgaaaa gctgaaatct gagttgcaat
    29281 ggcttgaatt agaaaacaag cttttgaact tatgggagca ttaggttact atgaaggatt
    29341 tgttccttat gtttcaaatt aatacaaaaa ccaagctgaa gaagaagaca aaccgctatc
    29401 tgataaatat atttttgaaa aaatcttagg aaaaacatat gcagccttca aaaaagatca
    29461 aattaatgag cgtgtcgaga aattaggtaa gttaaaacct attacaataa attacaacgg
    29521 aaaatcagaa gtaattgata gtaaagaaaa attacaagag cttatgaata aagccgttaa
    29581 agacgaagtg gctcaaatat agtaaaatga aataagaaca ggacaaatcg atcaggacag
    29641 tcaaatcgat ttctaaaaat gttttagaag tagaggtgta ctattctagt ttcaatatac
    29701 tataaaatca ggcaatacca cggctaaaaa gtttgagttt atcgaaacac cagtgcaaaa
    29761 actgaaaaaa gcgatttata aagctcatct caaagattca gatgacttta gaccagaaac
    29821 atccacataa atctttttga aagctgtttg aagctttgtc cttgctttct tagttcatag
    29881 atctgaactt tatcttcata actcaatttc ataataaaac accccaaaag ttagatttat
    29941 tctgtctaac ttttggggtg cagttcatta atcggtcgat ttttttggta gaaacagttg
    30001 cctgattaag ttgcaagtcg atagacggct tcggcataaa tatccatagc acggtacaaa
    30061 tcttctagaa cggcacattc atttgcctga tgttctgtct gcttcgctcc tgggaataag
    30121 gcgccgaagg ctacacaatt tggcatggtg cgagcaaaag tggcaccacc ggatgaaata
    30181 gcaggactgt tatcgccagt cttttcttgg tagatttgca tcagtgtgct aacgagttta
    30241 ctgtcttttg cgacgtatag aggcgctaga tagtcaaact cttcgtagcg gagttggtag
    30301 ttttgtgcac atcttgtaag caactctact agttcttcct tgtcagctaa gacaggagtc
    30361 cgaatgtcaa tacggatttc agaacgttca tgattgatca tgagacctgc gacattaaag
    30421 gataggtgac cagaaggttc atctgctata tcaccaaaga tttgtcttcc tgtgccgtct
    30481 tgacctgctt gtgttgcaag aaagctgaga gcagggtgtt cttggagagg agcaagaatg
    30541 gtagctagtc ggatgacagc attgatacct tgactagcat ccttagcatg ctttggcact
    30601 ccgagaaccg ttacggtttg ttcagtggat tggtaatcat aaccagcttc tttgagatcg
    30661 ttacaaacct gttcatagag gggaccttgg tagttggcct tgtctggtac aacgttaaag
    30721 gcgcctccta cttcaagctc tagttgatcc gatccagggc catgaagttt gacctgtaga
    30781 agtccttttt cagcataggt cagaggaaaa gatgagtcag gtgcaaagcc catgctggcc
    30841 tgttcttcga tggtattgta gcgtgccatg cagcgccaga gggtctcctc atcggtacca
    30901 aagataaagc gtacgcgctt tttgaactga ataccttggt ccagcaagct ttttactgca
    30961 tagagagctg cgagcgaagg gcctttatca tcttggacac cacgtccgaa tacccagccg
    31021 tctttgatag ttgcttcaaa tggcggtgtc tgccaatctg cttcatcacc tgatggaaca
    31081 acatccaaat gacagagaat ggccagaagc tctgctccct gaccgatttc tgcatatccg
    31141 taataacctt tagggtcaag ataggtagtg aaacctatgt ctcgacaaat ctctaaagtt
    31201 ttttctagga catcttggat tgcttgtcca aaaggtgttc cattttctcc ttcattgagt
    31261 actgaaggat aggaaatcaa ggtttttaat gatataagaa attcatcttt aacttgattt
    31321 gttatatcta ttttcatgga atcacctcac tcactatttt ataggaatgg aaggaaggtt
    31381 ccaaggagaa gaagggcgat ggtcactaca ataatagcga ctacgagttt gcccatgaat
    31441 ttccaccaag taccaatgtt gatacgtcca agtgcaagag ctcccatcac aataccagat
    31501 gttggtgcaa tcaagttcaa gacacctgaa gcagattggt aagcagtgat aatcaagcta
    31561 ggacggacat ttacaaattc tccaagtgga gccatgatac ccatagttgc gctggcaaga
    31621 ccagatgaag atgggatcaa gaatgacata ggtagataga agatataagt tacaacgata
    31681 aagacttgtg aagatagacc gctcaagcct tctttacccc agttgaggat tgtatcggta
    31741 atcataccgt cgttcatgat aacttgaata ccacgagcaa tcgctacgat caaggcaaca
    31801 ctgagcaagt cagcagcacc attcatgaag gaagagataa tcttatcttc tttaagacca
    31861 taaataacac caatcaggat acccataaag gcaaagagca ttgcgccttc tgggaagtac
    31921 caagtaccta gtgcagaagt agatgaaccg acaatattgc caataactgg aagaccagtc
    31981 aaccaagcat taaagtcatc aaaaatggta acgccaaggt ctgtccatgg aatgaagctc
    32041 aataccatca agatgaatgt caacacaaat aagaagagaa ctgatttttg tttgctgcta
    32101 agtgtagatt ctacagatga agattcttct acgttaaagt gtttcaaatc ttctttgcga
    32161 gtactataaa ccagtgactt agtcggatct ttttgaatct tatccgcata acggtaaaca
    32221 aaccaagtac taagagcagt caaggtaacc cagaagatca gacgaagtac gataccgtcc
    32281 cctgtaccaa ctcccgcagt cgctgaagca atacctgtcg caaatggatt cagagtagat
    32341 gccaaacagc cgatttgaga accgagcaaa ataattgcaa caccagtcag gctatcaaaa
    32401 ccaacggcca tcataactgg cacaaggagt ggatagaagg ccattgtttc ttcacccata
    32461 ccataagttg taccaccgag ggcaaacaaa ggcatcagta ccaaaattaa cattttttcg
    32521 cggcccttat acttcttcac gatagaggca atccctacgt caagagcacc agttttgttg
    32581 acaatgccaa ggaaaccacc aaccataagg atgaagaagg ctacatcaat cgctgcgctc
    32641 gtttctttaa tgagcgaacc ttcctctgga tgagtaccta gcatagcccg aatcggtgcc
    32701 atgaggacat cccaaatccc ttgtggattt tgaggctgag tctcgtaaat accttctata
    32761 aaggcccccg cagggataaa ccaagttagc acggccataa tagcaatgat tatcaataat
    32821 acggtgtaag atgaaggcat cttaaaccct tttttagctt tttcactcat ttgtttttcc
    32881 tcctgatgtc taacaaagtg taaaaaacca actactttct taaataaaca ttcaagaaaa
    32941 cgctttctat ttatatttgt tttaccatat taaagtctaa aaaactaata tcttttgaaa
    33001 tattgtacat gttttcaaga ataatttcta atttgatata aagatactag aaatagaata
    33061 catcttatta gtaaaacaac ttatcctttt tcaataattg ttccgctttc agattcaatc
    33121 aaggcgccta gattttcaag ggaagtaata actgcttttc cttctggacg accattgaca
    33181 aaagcgatag ctgcttctac ttttggaagc atgctacctg gtgcaaactg atcttgtttg
    33241 atatattctt ccagctgggc aacattcaca tgttccaatt tttcctggtt tggcttgttg
    33301 tagttaacaa atacataatc tacacctgtc aaaatgatga agaggtctgc atcaaccaat
    33361 tctgccaaac gttgggaagc gaagtcttta tcaataaccg cttcgacacc agtcaaatgt
    33421 ccattgtttt ctttgacgac gggaataccg ccaccacctg cagctacgac gacttgacca
    33481 ttatttaaaa gagtacggat ggtttcaatt tctttgatgt caacaggttt tggtgaggca
    33541 acgaccttac gccagccacg gccagcatct tccttgaaag tcgctccgct tttttcggct
    33601 tctgcttttg cttcttcttc tgaatagaaa ggaccgattg gtttactcaa gttaacaaaa
    33661 gctggatcat ttttatctac gacaacttgc gttacaacag aggcaacatt tttttcgatg
    33721 ccttcatcca agagagcatt ttgcaaagca tttttcaacc agaaaccgat gctaccttct
    33781 gtcatagcga caagtgagtc gagtgggaag gcagggttct tttcagagtc tgatgccaaa
    33841 tgttggagca agagattccc aacttgaggt ccattaccgt gagtgataat caaatcatct
    33901 ccatttttaa tcaattttac aagatgctta gctgtttcaa ctaaagcttc ttgttgagcc
    33961 tttgctgatg ggtcagaaga aagaatcgca tttcctccca aagctactac aattttacga
    34021 tttgccataa attctccttt atcacactca atagaatgcg tttagatttc aatttaatga
    34081 tttttcacat attttataag aaataataga ttaccattac ataaaagagg accggactaa
    34141 agctattagt cgcagccctc atagctgttg gtagacggtt tattatctaa aattatactt
    34201 taggaatata aaggttacca agtgtagcag ccataacagc tttgatagtg tgcatacggt
    34261 tttctgcttg atcgaagtgg cgagcgtact tgctgcggaa gacttcgtct gttacttcca
    34321 tttcttctac accaaatttt tcagcaacgt ctttaccata aacagtgtga gtatcgtgga
    34381 atgctggcaa gcagtgtagg aagatcaagt tttcattgcc tgctttttta actaagtcca
    34441 tattgacttg gtaaggttta agaagagcta cacgttctgc gaatttgtct tcttcaccca
    34501 ttgataccca aacgtctgtg taaagaacgt ctgcatcttt aactgcttca tcagcatctt
    34561 cagtgatgag aacatgtgcg ccactttctt tagcaaatcc ttctgccaat tcaacgattt
    34621 ctttttctgg gaagagttct tttggtgaga agatgtgaac attgacacca aggatagcac
    34681 ctgttacgag caagctgttg gcaacgttgt tacgtccatc accacagtat accaatgtca
    34741 agccttccaa gcgaccgaag ttttcttgaa cagtcaagta gtcagcgagc atttgagttg
    34801 ggtgccattc gtcagttaga ccgttccata ctggaacgcc tgagaattct gccaattctt
    34861 caaccatacg ttggctgaat ccgcggaatt caatcccgtc aaacatacgt cccaatactt
    34921 tagcagtatc ttcagtagat tcttttttac ccaactgaat atcatttgct ccgaggtatt
    34981 ctgggtgagc accaaggtcg atagccgcag ttgtaaaggc tgcacgagta cgagtagatg
    35041 ttttttcaaa taggagagcg atattcttgc cagcaaggta gtggtgttga atattgcgtt
    35101 ttttcaaatc tttcaagtga gctgaaagac caataaggta ttctaactct gcacgggtaa
    35161 agtctttttc tgctaagaag ctgcgtcctt ggaatactga atttgtcatt ttattatttc
    35221 ctctttctat tttttacatt ttctattgac gaatgccgaa cagcgattac acttcttcac
    35281 gttcaaatgg catagacata caacgaggtc caccacggcc ccgaaccaat tcacttccgc
    35341 gaatcttaat caagcgaagc ccgtattctt ccaaaatctt attggtcacg gtattgcggt
    35401 cataaacaac taccacacca ggtgcgatgg tcaaagtgtt agaaccgtcg ttccattgtt
    35461 cacgcgcagc tgctacgata ttgccaccac cgcaacgaat caaatgaact ttttctacac
    35521 caaggttttg agcaagaagt tcagctaagt cacctttctc ttcaacgatt ttaagttttt
    35581 cgttttcgta agtaactgag taaacgtgaa ggtcgccttc gatttctggg tgaatagtga
    35641 atttgtcata gtctaccata gtgaagacag tatccaagtg catgaattta cggttgttag
    35701 caaattcaaa ggccaaaact ttcttgaagc caacattttt cttgaagatg ttgaccaaaa
    35761 gtttttcgat agaagctgcg tctgtacgtt gagaaatacc tactgcaagg acgtctttag
    35821 aaagaactag ctcgtctcca ccttcgatac gcgtatcttc ttcacggttg tagaccaaat
    35881 ccacttttcc gccatagatt gggtggtatt tgaagatata cttaccgtag agtgtttcac
    35941 ggttacgagt gtctgcaaac atgtggttaa gcgatacggc gtttccaatt gttgcaaatg
    36001 ggtcgcgagt gaaatagagg tttggcatcg ggtcaattgc aaatggataa tctgattcaa
    36061 ctaagtcagt tagatcttta gcttcgtcag gaatttctgg caattcaact ttttgaatcc
    36121 cagccattgt tttttcaacc aattcttggt tgtccttgat gccgtgaagc aattcacgaa
    36181 tagcaacctt ggtttgacga tcacggatgt tggcttcgtc taagtattcc tcgataaatt
    36241 gatcgcggat ttctggagag gtcaatgatt cagcagcgag ttgttctagg tagagaacct
    36301 caattccttc atcgcgaaga gcttgggcaa atgcatcatg ttctttttga gcatcttcca
    36361 agaaaggaat atcatcaaaa agaagccttt caagatagtc cggcaacaag ttttctaact
    36421 ccttgcctgg acggtgcaac ataacttttt tcagtttccc aatttctgag aagacctgaa
    36481 ttggatgtga agacatgtat tttcctcctt aaaaattttg acttggcacc attttgggta
    36541 ccgcttacat gtatgttata acgcaattcc taggtaatgt caatggctat aatttctcgg
    36601 aaaataatat aaattatgat gtttagcaca attttatgtt attatacata acataggata
    36661 gaatacatag atacaaatgt ataaacttct ataaaaagga tataaaattt ttttaaaaaa
    36721 tttttcaaaa aatatacaaa tgaccaaaaa gtgtccaatt atcatctggt tatcacttgg
    36781 atctgtataa agagaaatgt ttgtgtgaaa ggataaaaag atgcaacatt cttttgaaga
    36841 tagattttgg agaagcattt cttgttcaat tgtacaaatt atagaatctt ttctgagtat
    36901 ttaggaagag ataattatct tattgaccct ctttttattt tttgttatag tcgacgaggt
    36961 gatagtttag aataatcact tattcacaat ctgtggaaaa gtctggatag tgaatggtct
    37021 tcacacaatg acctgaaaga agcctgagaa taattatgga gagtagcatt ctgagaggtg
    37081 ttagcagaac catatgacag agctgtttga agagggaata ttgaggagaa aaatcctgag
    37141 cctaccagtt ggagttggaa agagctggct gttagatcat ggtttattat ccacaacctg
    37201 tggataacct tgtgaacaag agaagttgca aaagaaggag atatataacg atgaagaaaa
    37261 tcaaaccgca tagaccgtta ccaagtcaga ctcagctagc ttatctggga gatgaactag
    37321 cagcctttat ccattttgga cctaatactt tttataatca ggaatgggga acaggtcagg
    37381 aggatcctga acgctttaac ccgacacagt tagacgcacg tgagtgggtt cgcgtgctca
    37441 aggaaacggg cttcaaaaag ttgattttgg tggtcaagca ccatgatggc tttgtccttt
    37501 atccgacagc tcacacagat tattcggtta aggtcagtcc ttggaggaga ggaaagggcg
    37561 acttgctcct tgaagtatcc caagctgcca cagagtttga tatggatatg ggggtctacc
    37621 tgtcaccgtg ggatgcccat agtcccctct atcatgtgga ccgagaagcg gactacaatg
    37681 cctattatct ggctcagctg aaggaaatct tatcaaatcc tgcctatgga aatggaggga
    37741 aatttgctga ggtttggatg gatggtgcca gaggagaggg cgcgcaaaag gttaattatg
    37801 aatttgaaaa atggtttgaa accattcgtg acctgcaggg caattgcttg attttttcaa
    37861 cagaaggcac cagtatccgc tggattggca atgaacgagg gtatgcaggt gatccactgt
    37921 ggcaaaaggt gaatcttgat aaactaggaa cagaagcaga gctgaactat cttcagcacg
    37981 gggatccctc gggcacgatt ttttcaatcg gagaggcaga tgtttccatc cgtccaggct
    38041 ggttctacca tgaggatcag gatcctaagt ctctcgagga gttggtcgaa atctactttc
    38101 actcagtagg gcgaggaact ccactcttgc ttaatattcc gccgaatcaa gctgggctct
    38161 ttgatgcaaa ggatattgaa cgactttatg aatttgcgac ctatcgcaat gagctctata
    38221 aagaagattt ggctctggga gctgaggtat ctggtccagc tctttccgca gactttgctt
    38281 gtcgccattt gacagacggc cttgagacca gctcttgggc aagcgatgca gacttgccca
    38341 tccagttaga actcgattta ggttctccta aaacttttga tgtaattgag ttaagagaag
    38401 atttgaagct agggcaacga atcgctgctt ttcatgtgca agtagaggtg gatggtgtct
    38461 ggcaggagtt tggcaggggc ttcacagttg gtcataagcg cctcttgcga ggtccgctag
    38521 tagaggcaca aaaggtgcgc gtgatgatta ccgaggcaca atctatccct gtattgacca
    38581 agatttccct ttataaaact cctgggttat caaaaaaaga agttgttcag gaactagcat
    38641 ttgcagaaaa aagcctagct gtggcaaagg gagagactct tcattttagg attgaacgta
    38701 gtgaaagtag ctcctcttta gaggctaaga tttcgattca accggggaca ggtgtccatg
    38761 gtgtcgccta tcaggatgag attcaagtcc ttgcgtttca agctggtgag actgaaaaaa
    38821 gtctgacgct accaaccttg tatttcgcag gagataaaac cttggatttc tatctgaacc
    38881 taacggtgga tggtcagctt gtggatcaac ttcaagtcca agtttcataa aagaagaacc
    38941 tttgcgcgat gcaaaggttc ttttggttat tagtgacttg gtaaccagct gagggtgaaa
    39001 gttagttgtt cagcttttaa gaggtcttgg tgttgaatag ttgatacgag tgttttgtcc
    39061 agtcggcatt ctttgacaaa gttaaaatgg ttgtggtttt gtttagtatg gatatccagc
    39121 catttatctt ctttagctag gtagactcgt agatggtcaa agagagggat tccgaggtca
    39181 tagcttggtt ttcctggaca ggttggataa aatccgagag ctgaccagat gtaccaagca
    39241 gagagactac cattgtcttc atctccagga taggcttccc aacttgggtg aaaagctttc
    39301 tgacggagcg tcttgataag aagggcagtg tagtcagggt aatcgctgta gcggaagaga
    39361 taaggaatgt ggaaactagg ctggttggaa atggctattt gtccaaaagg agcagtagcc
    39421 atctcgctca tttcgtgaat ttcgtaacca tagcctgttg tttcaaagag gggagcatct
    39481 tgacaggctt tcaaaagata gttgctaaag gtttcttttc cacccatcag ttggattaag
    39541 ccagggatgt cgtggagaac gcctaaagta gcttgaatgg cagagcattc agcgtagtct
    39601 cgcccccaac tataaggaga gaagtcaggg tgaaagtttc cttgattgtc tcgtgctcgc
    39661 atgtaacctg tctcagcgtc aaatagctgg cggtaatttt gtgaagtagc cttgtaggtt
    39721 tcagcgattt ctatgttctc tagttttttg gcacagctgg cgatacaaaa gtcactatag
    39781 gcatagtcta gagtatggct aacactttcg tggtggtcgg tagagaggta acctagttct
    39841 tggtattggg ctagtccgtg gcggccattg atgccgagag ggtcggcttt gctggctgtt
    39901 tcgagcatgg cttggaagag ttctccttct aggtcagggg ccatgtcctt gcaggcgcta
    39961 tctgcgataa taccgtctaa aagtgtacct ggcatcatac cccgttcatc tggagccagc
    40021 cattttggaa ggaaaccagt atcgcggtag ctattgagga aaccttctaa aaagcgttga
    40081 tagtgctccg gtatgataag ggcaaagagg gggaaggtgg tgcggaaggt atcccagaaa
    40141 ccattgttgc taaagaggac accaggcttg acagtaccag tagccagatc catgtggatg
    40201 gcttgccctg actcatcaac ctcataaaaa gtctgtggga agaggaagag tctgtagaga
    40261 cagtggtcaa agaaggttcg gtcagcctct cctgtctcta taatgtcaaa acgatggagg
    40321 agattttccc aatccgcttg ggcacttgct ttacagctat caaaatcttc ttgaggtaga
    40381 ttgattagag cttgagaagg agagatgaaa gaagtggcta gttgcatctc ggtttgacta
    40441 cttgctaagt caattcgcca gtctccccct tcttggctga tagcaagaat atccgtgttc
    40501 atttgcaggg cagtgaacat cgttagcgaa tttttgttag tttcagtttt accttcttgt
    40561 cgcagggcaa gagtccgctt atctacttgc tctacggtca gttcatctgc tgcgtgaaga
    40621 tagagggaga gggctttgcc ttgcttttga ttcaaacgaa tagaagcacc atagcaagtc
    40681 ggtgtgagct gggtttcaat ctgataacgc agagaaaaga gcttcaaata gtgaggctgg
    40741 aagcaagctt tatctatatc ataagaagac tggcggtgaa agaggctgtc tccacccagt
    40801 tgactggtga caggtgtcag aaggagccaa gagtagtccc caatccaagg actgggctgg
    40861 tgagttaatc gaatcccctg aaagataggc agatgcggat caaaaaacca agatccatcc
    40921 tggtcactgg tctggggcac aaagtaattc attccaaaag gcacgcctgt gtatggcagg
    40981 gtatttcccc gagagaaggc atgcttgcta gcagtaccaa agcgggtatc gatggtttca
    41041 agtagtggtt tcatagtctt tcctttagct gtttttctac attatatcag aaaaagaggg
    41101 cctttagaaa aggagtttca aaaataacta ttttgtagaa aaatgactat catttgtgta
    41161 tgtattttct gtctcaaaag ctatatactg aacatgaaac ttgtttgaaa gaggtaaaat
    41221 ttaaaatggt ttattcgaaa gaaatcgtca gagagtggct ggatgaagta gcagagcggg
    41281 ctaaggacca tccagagtgg gtggatgttt tcgagcgttg ctacaccgat accttggaca
    41341 atacggttga aatcttagaa gatggttcaa cttttgtctt gactggggat attcctgcta
    41401 tgtggcttcg ggattcgaca gcccaactca gaccctacct tcatgtagct aaaagagatg
    41461 ccctcctgcg tcagaccatt gcaggtttgg tcaaacgtca gatgaccttg gtactcaagg
    41521 atccttatgc caattccttc aacatagagg aaaactggaa ggggcaccac gagaccgacc
    41581 acaccgacct taatggctgg atttgggaac gcaagtatga ggtggactcg ctttgctatc
    41641 ctttgcagtt ggcttatctc ctctggaaag aaactggcga gactagtcag tttgatgaga
    41701 cttttgtcgc agcgactaag gaaattcttc atctgtggac ggtagaacaa gatcataaga
    41761 actctcctta tcgttttgtc cgagatacgg accgcaagga agacaccttg gtaaatgatg
    41821 gctttggacc tgattttgca gtgacaggaa tgacttggtc agcctttcgt ccgagcgatg
    41881 actgctgtca gtatagttac ttgattccgt caaatatgtt tgctgtagta gtcttgggtt
    41941 atgtgcaaga aatcttcgca gcattaaacc tagctgatag ccagagtgtt attgctgatg
    42001 ccaagcgtct tcaggatgaa atccaagaag gaatcgaaaa ctacgcttac accaccaaca
    42061 gcaagggcga aaagatttac gcttttgaag tggatggcct aggaaatgcc agcatcatgg
    42121 atgatccaaa tgtaccaagt ctactagctg cgccctatct gggctactgt tcggtcgatg
    42181 atgaagtgta tcaagctact cgtcgtacca ttttgagctc tgaaaatcca tatttctacc
    42241 aaggagaata cgctagcggt ctcggaagtt ctcatacctt ctatcgctat atctggccaa
    42301 tcgccctttc tatccaagga ttgacaacaa gagataaggc agagaaaaaa tttttgctgg
    42361 atcagctggt tgcctgcgat ggtggtacag gtgtcatgca cgaaagcttc cacgtagatg
    42421 atccgaccct ctactctcgt gaatggttct cctgggctaa catgatgttc tgtgagttgg
    42481 tcttggatta tttagatatt cgctaagggg ctcgctttag ctcaaccgat tcttatcaga
    42541 atcacaagtt tacatttaaa acgttaaaat ttaaatttag aatgaggttt tacttcatgg
    42601 aaaatgttgt tgtacatatt atctcacata gccactggga ccgtgagtgg tacttgcctt
    42661 ttgaaagcca tcgtatgcag ttggtggaat tgtttgacaa tctctttgaa ctctttgaaa
    42721 atgaccctga gttcaagagt ttccacttgg atggacaaac tattgtcctt gatgactact
    42781 tacaaattcg ccctgaaaat cgcgacaagg tccaacgcta cattgacgag ggcaaactta
    42841 aaattggtcc cttttacatc ttgcaggatg actacttgat ctccagtgaa gccaatgtcc
    42901 gcaatacctt gattggtcaa caagaagctg ccaaatgggg taaatcaacc cagattggct
    42961 actttccaga tacctttgga aatatgggac aagcgcctca aattcttcaa aaatcaggca
    43021 ttcacgtggc ggcctttggt cgtggtgtga agccgattgg atttgacaac caagtccttg
    43081 aagatgagca gtttacatcc cagttttcag aaatgtactg gcagggtgtg gatggtagtc
    43141 gtgttttagg tattctcttt gctaactggt acagtaatgg gaatgaaatc ccagttgaca
    43201 aagatgaggc cttgaccttc tggaaacaaa aattgtcaga tgtgcgtgcc tacgcttcga
    43261 ccaaccaatg gttgatgatg aacggctgtg accaccagcc tgtacagaaa aatctgagcg
    43321 aagccattcg tgtggcaaat gaactcttcc cagatgtaat ctttgttcat agttcttttg
    43381 atgaatatgt tcaagctgta gaaggtgcgc ttcctgaaca cttatcaact gttacaggcg
    43441 agttgaccag tcaggaaaca gatggctggt acacacttgc caacacttct tcatcccgca
    43501 tttacctaaa acaagccttc caagaaaata gcaacctcct agagcaagtg gtagaaccct
    43561 tgactattat cactggtgga cataaccaca aggaccagtt gacctatgct tggaaaacac
    43621 ttttgcagaa tgcgccacat gatagtatct gtggctgtag cgtggacgaa gttcaccgcg
    43681 agatggaaac gcgttttgcc aaggtcaacc aagtaggaaa ctttgttaaa agtaatttgc
    43741 tcaacgagtg gaagggtaaa attgctacgg ataaggctca aagtgactat ctctttactg
    43801 tcattaacac aggcttgcat gataaggtcg atactgtcag cacagtgatt gatgtggcga
    43861 cttgtgattt caaggaattg cacccaacag aaggctacaa aaagatggcc gctcttatct
    43921 tgccaagtta ccgtgtggag gacttggatg gtcgtcctgt agaggctaca atcgaagacc
    43981 tcggagctaa ttttgaatac gatttaccaa aagacaagtt ccgccaagct cgtattgctc
    44041 gacaagtgcg cgtgaccatt ccagttcagc tagcgccgct ttcttggaca accttccaat
    44101 tgctggaagg aaaacaagaa caccgtgagg gtatttacca aaacggagtg attgatacac
    44161 cattcgtaac ggtgagtgtg gatgacaaca tcacagtcta tgacaagaca actcacgaag
    44221 cctatgaaga ctttatccgc tttgaagacc gtggggacat cggaaacgag tatatctatt
    44281 tccaaccaaa aggaacagag ccaatctttg cagagcttaa gggccacgag gtcttggaaa
    44341 acacagcttg ctatgctaaa atcttgctca aacatgaatt gaccgtgcct gtcagcgcgg
    44401 atgaaaagct agaagaagag caacaaggta tcatcgagtt tatgaagcgt gaggctggac
    44461 ggtcagaaga attgacaaac attcctctgg aaactgagtt gactgtcttc gttgacaatc
    44521 cacaaatccg cttcaagact cgctttacca acactgccaa ggatcaccgt atccgtctct
    44581 tggtcaagac tcataacacg cgtccaagta atgattctga aagtatctat gaggtggtga
    44641 cacgaccaaa caaaccagct gcttcatggg aaaatcctga aaatcctcaa caccaacaag
    44701 cttttgtcag tctgtatgac gatgaaaaag gggtgactgt atccaataag ggattgaatg
    44761 aatacgaaat ccttggggat aacaccattg ccgtgaccat tttgcgtgca tcaggtgagc
    44821 taggtgactg gggctacttc ccaacgccag aagcacaatg cttgcgggag tttgaagtcg
    44881 agtttgcact tgaatgccac caagcccaag aacgcttctc agcctatcgt cgtgccaaag
    44941 ccttgcagac atcgtttacc agccttcagc ttgctagaca ggaaggaagc gtggttgcga
    45001 ttggtagcct cttgagccat tctgttctca gcataccgca agtttgtcca acagccttta
    45061 aagtggcgga aaatgaagaa ggctatgtcc tccgttacta taatatgagt caagaaaatg
    45121 tgcgcatatc agaacatcaa caaaccattc ttgacttact tgagcgacca tatccagttc
    45181 attcaggact attggctcca caagagattc gtacagaatt catcaaaaaa gaagaaattt
    45241 aatttcaaaa agtaaacatc aaaagaaagg aggggcgaaa aagtaagaac taactgctga
    45301 ttcgcccctt tttatggtaa aaacaatgac cattgcaacg attgatatcg gagggactgg
    45361 gattaagttt gccagtctga ctcctgatgg gaaaatactg gataagacaa gtatttcaac
    45421 gcctgaaaac ttggaggatt tactaacgtg gctagatcaa cgcttgtcag aacaggatta
    45481 cagtgggatt gctatgagcg ttccaggtgc ggtcaatcaa gagacaggtg tgattgatgg
    45541 cttcagtgcg gtgccctata tccatggctt ttcttggtat gaggcgctta gctcttatca
    45601 gctacctgtc catttagaaa atgatgccaa ctgcgttgga ctcagtgaac tactagctca
    45661 tccagagctt gaaaatgcag cctgtgtcgt gattgggaca gggattggcg gagccatgat
    45721 tatcaatggt agacttcatc gaggtcgcca cggtctgggt ggagaatttg gctacatgac
    45781 aacccttgcc cctgctgaaa aacttaataa ctggtcgcaa ctagcatcaa ctgggaatat
    45841 ggtacgatac gtgattgaaa aatctggtca tactgattgg gacggtcgca agatttacca
    45901 agaggccgca gctggtaatg ctctttgtca agaagccatt gagcgcatga accgcaatct
    45961 gacgcaaggc ttgctcaata tccagtatct catcgatcca gatgtcatca gtctgggtgg
    46021 ctctatcagt caaaatccag attttatcca aggtgttaag aaggctgttg aagactttgt
    46081 cgatgcctac gaagaataca cggtcgcacc agttatccag gcctgcacct atcacgcaga
    46141 tgccaatctc tacggtgccc ttgtcaactg gctacaggag gaaaagcaat ggtaagattt
    46201 acaggactta gtcccaaaca aacgcaagct attgaggttt taaaaggtca catttctcta
    46261 ccagatgtgg aagtggctgt cactcagtct gaccaagcct ctatctctat ccagggtgag
    46321 gaaggtcact atcaattgac ctaccgcaaa cctcaccaac tttatcgtgc cttgtccttg
    46381 ttggtaacag ttctagcaga agctgataaa gtagagattg aggaacaagc agcttacgaa
    46441 gatttggctt acatggttga ctgttctcga aatgcggtgc tgaatgtggc ttctgccaag
    46501 cagatgattg aggtcttggc tctcatgggc tactcaacct ttgagcttta catggaagac
    46561 acttaccaga ttgaagggca gccttacttt ggctatttcc gtggagctta ttcagcagag
    46621 gagttgcagg aaatagaagc ctatgctcaa cagtttgaca tgacctttgt accatgcatc
    46681 cagaccttgg cccacttgtc ggcctttgtc aaatggggtg tcaaggaagt gcaggagctc
    46741 cgtgatgtag aggacattct tctcattggc gaagaaaagg tttatgacct gattgatggc
    46801 atgtttgcca cgttgtctaa actgaagact cgcaaggtca atatcgggat ggacgaagcc
    46861 cacttggttg gtttgggacg ctacctgatt ttgaacggtg ttgtggatcg tagtctcctc
    46921 atgtgccaac acttggagcg cgtgctggat attgctgaca aatatggttt ccactgccag
    46981 atgtggagtg atatgttctt caaactcatg tcagcggatg gccagtacga tcgtgatgtg
    47041 gaaattccag aggaaactcg tgtctaccta gaccgtctca aagaccgtgt gactctggtt
    47101 tactgggatt attatcagga tagcgaggaa aaatacaacc gtaatttccg caatcatcac
    47161 aagattagcc atgaccttgc atttgcaggg ggagcttgga agtggattgg ctttacacct
    47221 cacaaccatt ttagccgtct agtggctatc gaggctaata aagcctgccg tgccaatcag
    47281 attaaagaag tcatcgtaac gggttgggga gacaatggtg gtgaaactgc ccagttctct
    47341 atcctaccaa gcttgcaaat ctgggcagaa ctcagctatc gcaatgacct agatggtttg
    47401 tctgcgcact tcaagaccaa tactggtcta acggttgagg attttatgca gattgacctt
    47461 gccaacctct taccagacct accaggcaat ctcagcggta tcaatcccaa ccgctatgtt
    47521 ttttatcagg atattctttg tccgattctt gatcaacaca tgacacctga acaggacaaa
    47581 ccgcacttcg ctcaggctgc tgagacgctt gctaacatta aagaaaaagc tggaaactat
    47641 gcctatctct ttgaaactca ggcccagttg aatgctattt taagtagcaa agtagatgtg
    47701 ggacgacgca ttcgtcaggc ctaccaagcg gatgataaag aaagtttaca acaaatcgcc
    47761 agacaagaat taccagaact tagaagccaa attgaagact tccatgccct ctttagtcac
    47821 caatggctga aagaaaacaa ggtctttggt ttggatacag ttgacatccg tatgggcgga
    47881 ctcttgcaac gcatcaaacg agcagaaagc cgtatcgagt tttatctggc tggtcagctt
    47941 gaccgcatcg acgagctgga agttgaaatc ctaccattta ctgacttcta cgcagacaag
    48001 gatttcgcag caactacagc taaccagtgg cataccattg cgacagcttc gacgatttat
    48061 acgacttaat actcttcgaa aatctcttca aaccacgtca gcttccatct acaacctcaa
    48121 aacagtgttt tgagcagcct gcagctagct tcctagtttg ctctttgatt ttcattgagt
    48181 ataaaaacaa gaacaccttg cttggcgcag ggtgtttcgc gtgaaacaga agaattatct
    48241 ggtttcaaat gctacagtta aaattagtaa aacaagaaat agaagctgaa aagccagcat
    48301 ctgtagaagc ttggatcatt tccgtcaaat taaaaaaggt tgctaccgac atatatagat
    48361 tccaaaaaca aaaacgttag cggaactagc agatgtgatt ttatggagtt tcgattttgt
    48421 aaatgatcat gctcatgcat ttttcatgga taatgttgag tggagtcatg cagattctta
    48481 ctttcttagc tttgttagtg acgatgttga agaacgttac atagaaaatg tctatctgga
    48541 tagcctaagt gtcaaacaaa aatttaagtt tattttcgac ttcggtgatg aatggcgttt
    48601 tgaatgctaa gtgctgagag aaatcgagac agaggacgaa gaagcttatc tcgtacgttc
    48661 ggttggaacg ttgccagaac aatatccaga ttatgatggt tttgactatg aagaatggta
    48721 aaattgaaat cagtctgtgt aggcttagta tttcaataga cttcctgcaa aactagaatc
    48781 ctagttcatg attgataata ccagcactca aattcattcg taatccgaag cgtttacgat
    48841 gatttcgata ggttgttgaa aatattttaa acgtttttac tttggcaaag atgttctcaa
    48901 ccttgcttct ttccttagat agcgcatggt tataggcttt attttcagct gttagcggct
    48961 tgagtttgct ggatttacgt ggagtttgta cttgaggata tatcttcatg agcccttgat
    49021 aaccactgtc agccaagatt ttaccagctt gtccgatatt tctgcgactc attttgaaca
    49081 acttcatatc atgacaatag ttcacagtga tatccaaaga aacaatctcc cttgacttgt
    49141 gacaatcgct tgagccttca tagcgtggca tttcttttta ccagaatcat tcgctaattc
    49201 ttttttaggg cgattgattt gtacttccgt cgcatcaatc attaccgtgt cctcagaact
    49261 gagaggagtt cttgaaatcg taaaaccact ttgaacaaga gttacttcaa cccattagct
    49321 ccgacggagt aagttgcttt cgtggatacc aaaatcagcc gcaatttctt cataagttcg
    49381 atattctcgc acatattgaa gagtggccat aagaaggtct tctaggctta atttaggttt
    49441 tcgtccacct tttgcgtgtt taagttgata agctgttttt aatacagcta acatctcttc
    49501 aaaagtcgtg cgctgaacac caacaagacg cttaaatcgt gcatcagtta gttgtttact
    49561 tgcttcataa ttttgtttcg cagggagtct attgactctt tggtaggtgt caatgttttt
    49621 ttcatctatc ccgagaatta ttttcccgcc atttgtattt gcaaatgctg agtaggtttc
    49681 ccagaaagac tctggaagat tgtttttagc ttttttgtat tctaaatcaa ccccttcaaa
    49741 ttttaagtcc atatttttcc tttacatctg ttttttgtgg ttctggtatt tgttcaagtt
    49801 gagtgataat atagcgaatt gaatttcgag agtttttact cagttaattt cttttttaac
    49861 ccactttaat ttctttttta acactggtta aaaaagaaat taaagtgggt taattttcct
    49921 tgacttaaaa tttaaaaatg atatactgtg tttatggaga gatgacaatt tataaaatgt
    49981 actactctat tctactagat aatgattgaa taaaactttt tataacaacg gctagcaaag
    50041 ttataatttt atatctatta gaaaataaat atgtaaggaa atttaaatga aaaaaactac
    50101 aatattatca ttaactacag ctgcggttat tttagcagca tatgtcccta atgaaccaat
    50161 cctagcagat actcctagtt cggaagtaat caaagagact aaagttggaa gtattattca
    50221 acaaaataat atcaaatata aggttctaac tgtagaaggt aacataggaa ctgttcaagt
    50281 gggtaatgga gttactcctg tagagtttga agctggtcaa gatggaaaac cattcacgat
    50341 tcctacaaaa atcacagtag gtgataaagt atttaccgtt actgaagtag ctagtcaagc
    50401 ttttagttat tatccagatg aaacaggtag aattgtctac tatcctagct ctattactat
    50461 cccatcaagc ataaaaaaaa tacaaaaaaa aggcttccat ggaagtaaag ctaaaactat
    50521 tatttttgac aaaggcagtc agctggagaa aattgaagat agagcttttg atttttctga
    50581 attagaagag attgaattgc ctgcatctct agaatatatt ggaacaagtg cattttcttt
    50641 tagtcaaaaa ttgaaaaagc taaccttttc ctcaagttca aaattagaat taatatcaca
    50701 tgaggctttt gctaatttat caaatttaga gaaactaaca ttaccaaaat cggttaaaac
    50761 attaggaagt aatctattta gactcactac tagcttaaaa catgttgatg ttgaagaagg
    50821 aaatgaatcg tttgcctcag ttgatggtgt tttgttttca aaagataaaa ctcaattaat
    50881 ttattatcca agtcaaaaaa atgacgaaag ttataaaacg cctaaggaga caaaagaact
    50941 tgcatcatat tcgtttaata aaaattctta cttgaaaaaa ctcgaattga atgaaggttt
    51001 agaaaaaatc ggtacttttg catttgcaga tgcgattaaa cttgaagaaa ttagcttacc
    51061 aaatagttta gaaactattg aacgtttagc cttttacggt aatttagaat taaaagaact
    51121 tatattacca gataatgtta aaaattttgg taaacacgtt atgaacggtt taccaaaatt
    51181 aaaaagttta acaattggta ataatatcaa ctcattgccg tccttcttcc taagtggcgt
    51241 cttagattca ttaaaggaaa ttcatattaa gaataaaagt acagagtttt ctgtgaaaaa
    51301 agatacattt gcaattcctg aaactgttaa gttctatgta acatcagaac atataaaaga
    51361 tgttcttaaa tcaaatttat ctactagtaa tgatatcatt gttgaaaaag tagataatat
    51421 aaaacaagaa actgatgtag ctaaacctaa aaagaattct aatcagggag tagttggttg
    51481 ggttaaagac aaaggtttat ggtattactt aaacgaatca ggttcaatgg ctactggttg
    51541 ggttaaagac aaagg
//
LOCUS       DBERPV010000013        45597 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.13, whole genome shotgun sequence.
ACCESSION   DBERPV010000013 DBERPV010000000
VERSION     DBERPV010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 45597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45597
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.13"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..147)
                     /locus_tag="ACL8C7_000972"
     CDS             complement(<1..147)
                     /locus_tag="ACL8C7_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HGS1395198.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINKDTHKEIIAKLDYDAPSCP
                     ECGNQ"
     gene            340..837
                     /locus_tag="ACL8C7_000973"
     CDS             340..837
                     /locus_tag="ACL8C7_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HGS1395199.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTAWDFTM
                     FEEKS"
     gene            837..2492
                     /gene="dnaX"
                     /locus_tag="ACL8C7_000974"
     CDS             837..2492
                     /gene="dnaX"
                     /locus_tag="ACL8C7_000974"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HGS1395200.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSTLDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNAGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            2520..2714
                     /locus_tag="ACL8C7_000975"
     CDS             2520..2714
                     /locus_tag="ACL8C7_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HGS1395201.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2864..3634
                     /gene="sufC"
                     /locus_tag="ACL8C7_000976"
     CDS             2864..3634
                     /gene="sufC"
                     /locus_tag="ACL8C7_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HGS1395202.1"
                     /translation="MSVIEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3662..4924
                     /gene="sufD"
                     /locus_tag="ACL8C7_000977"
     CDS             3662..4924
                     /gene="sufD"
                     /locus_tag="ACL8C7_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HGS1395203.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4935..6161
                     /locus_tag="ACL8C7_000978"
     CDS             4935..6161
                     /locus_tag="ACL8C7_000978"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HGS1395204.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILAEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQFASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLAMALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            6148..6588
                     /gene="sufU"
                     /locus_tag="ACL8C7_000979"
     CDS             6148..6588
                     /gene="sufU"
                     /locus_tag="ACL8C7_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HGS1395205.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQGQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6641..8053
                     /gene="sufB"
                     /locus_tag="ACL8C7_000980"
     CDS             6641..8053
                     /gene="sufB"
                     /locus_tag="ACL8C7_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HGS1395206.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8284..9525)
                     /gene="pbp3"
                     /locus_tag="ACL8C7_000981"
     CDS             complement(8284..9525)
                     /gene="pbp3"
                     /locus_tag="ACL8C7_000981"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase PBP3"
                     /protein_id="HGS1395207.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9628..10737
                     /gene="cozE"
                     /locus_tag="ACL8C7_000982"
     CDS             9628..10737
                     /gene="cozE"
                     /locus_tag="ACL8C7_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell elongation protein CozE"
                     /protein_id="HGS1395208.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLVNPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            11383..11730
                     /gene="ssrA"
                     /locus_tag="ACL8C7_000983"
     tmRNA           11383..11730
                     /gene="ssrA"
                     /locus_tag="ACL8C7_000983"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(11900..11987)
                     /locus_tag="ACL8C7_000984"
     tRNA            complement(11900..11987)
                     /locus_tag="ACL8C7_000984"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11951..11953),aa:Ser,seq:gga)
     gene            12149..12889
                     /locus_tag="ACL8C7_000985"
     CDS             12149..12889
                     /locus_tag="ACL8C7_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGS1395209.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            12886..13797
                     /gene="pfkB"
                     /locus_tag="ACL8C7_000986"
     CDS             12886..13797
                     /gene="pfkB"
                     /locus_tag="ACL8C7_000986"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HGS1395210.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRVDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            13794..15746
                     /locus_tag="ACL8C7_000987"
     CDS             13794..15746
                     /locus_tag="ACL8C7_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HGS1395211.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAL
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            15883..18135
                     /locus_tag="ACL8C7_000988"
     CDS             15883..18135
                     /locus_tag="ACL8C7_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HGS1395212.1"
                     /translation="MERKEAIQRMLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGS
                     LAYLAIFGLLIYLFFFKWIRKQEGLLSGFFTIFTGLLLIFEAYLVWKYGLDKSVLKGT
                     MAQVVTDLTGFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWS
                     VYDIAEFFSRGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPP
                     ADMETGEILTEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAK
                     EALEYKLPSLQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVT
                     KYEVKPAVGVRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFR
                     ELWEQSQTKAENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASI
                     LMKARPDQVKFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYEL
                     FAKVGVRNIAGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRL
                     GQKARAAGIHMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLL
                     GRGDMLFKPIDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGE
                     FSDGDAGGDPLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAE
                     GTKPRKVLQQ"
     gene            complement(18180..18614)
                     /locus_tag="ACL8C7_000989"
     CDS             complement(18180..18614)
                     /locus_tag="ACL8C7_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6556 family protein"
                     /protein_id="HGS1395213.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNTKKEPTTSQTTTIVKEIQKESPQENTSPNKENKTSQEKTQQEETPKSSVKE
                     EKKEEQKTSTQDSSTPAPTPSKPATENEKQSNTPTSENKTNQ"
     gene            18777..20861
                     /locus_tag="ACL8C7_000990"
     CDS             18777..20861
                     /locus_tag="ACL8C7_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS1395214.1"
                     /translation="MFEIRNLSLSFAGRRLLEPTDLIFERGKVYTIYGKSGVGKSSLL
                     NKIGLLSATYPSVSYFFDGKEIDIENKKSVSVFIAEEVAFVFQGRNLINDLTVFENLR
                     LALNFYDLSPDEIESKIDTVLADLQISSLKHAYPEDLSGGEEQRVAIARALVTGKTLI
                     LADEPTSSLDKENREKVSALLIDLAHKYHKIVLIVSHDEAMIAIGDVQLHFKDHKLVG
                     NCLILNSDEGIKDSKKWSSCLSSSHTKLSVLKHRRPFLPRLLAFFISLVVAIAVTSIN
                     FQSLFADKYHQLVNNSLENGFLVINDSLHLQTTKVLDDFLSFDKEEITSISTSQNIQT
                     VNPYIEFLSLGMTFDNSKDYSQLQKNFQPTLTIDGQTRSLTRNFSIQPLYQTNTTQRQ
                     IEYFDRSNEKGIYLSEQFISDEKLPNIVSGTTVTLTFYIPISLYESSIEKEGNILKGD
                     GDLFVKVDKTYPVLGIVKKSYPFEYSPYGNTLFMNIAEMEELQNEAIQQHPMTKMALD
                     GFPLKSWMPSAIHVLLKDSGAIPEELSRIRAISSQITILSSYENYEEFNKGLTYIRQF
                     LMLLSLVLLILVIAVLSFVFFLLNRPRRFEVGILKSLGYSTQNIVWLFLKELIGYGKT
                     ISILASCLLVILSILAMQVLKLEISDVFKFYLTSVFTLIGLSVSVLIISGLLPIYTTC
                     RQTVVDTIRKNG"
     gene            20871..21248
                     /locus_tag="ACL8C7_000991"
     CDS             20871..21248
                     /locus_tag="ACL8C7_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395215.1"
                     /translation="MKHKIMKKIIVVVFAIPWLTFLSQVHADYVSKSSSLDGYSLVGL
                     NVLNVTFNASGYSDTYSGSVSNMYFTDWAWFPNTISNRSTWKSSIPYGQRANGTVHID
                     VGVNSPWGAVNLWGGQNYFSLDF"
     gene            21408..22550
                     /locus_tag="ACL8C7_000992"
     CDS             21408..22550
                     /locus_tag="ACL8C7_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGS1395216.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSVQPIEAI
                     SKLLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            22559..23773
                     /gene="thiI"
                     /locus_tag="ACL8C7_000993"
     CDS             22559..23773
                     /gene="thiI"
                     /locus_tag="ACL8C7_000993"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HGS1395217.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGGAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            23909..24733
                     /locus_tag="ACL8C7_000994"
     CDS             23909..24733
                     /locus_tag="ACL8C7_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGS1395218.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFYSKESFIGYSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIDETYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYIECQKLSPDQRIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            24755..25494
                     /locus_tag="ACL8C7_000995"
                     /pseudo
     CDS             24755..25494
                     /locus_tag="ACL8C7_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            25507..26673
                     /locus_tag="ACL8C7_000996"
     CDS             25507..26673
                     /locus_tag="ACL8C7_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HGS1395219.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMVPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASEFEPQYCLATSRRANAHYVY
                     SEENLLAKYSQQFKVKKIMPEAFAELQGDYFYMLTTPSRQEMDQMIADFGQRQE"
     gene            27181..28674
                     /locus_tag="ACL8C7_000997"
     CDS             27181..28674
                     /locus_tag="ACL8C7_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HGS1395220.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGATDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            28687..29214
                     /locus_tag="ACL8C7_000998"
                     /pseudo
     CDS             28687..29214
                     /locus_tag="ACL8C7_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818406.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
     gene            29226..30344
                     /locus_tag="ACL8C7_000999"
     CDS             29226..30344
                     /locus_tag="ACL8C7_000999"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS1395221.1"
                     /translation="MKKVKLGQVATFINGYAFKPQDWSSEGKEIIRIQNLTKTSKGIN
                     YYSGTIDKKYIVEAGDILISWSGTLGVFQWCGRSAVLNQHIFKVVFDKIDIDKSYFKY
                     VVEKGLQDAVKHTHGSTMKHLTKKYFDNIIVPYTNLGEQQRIASELDLLSKLILRRQE
                     QLEELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLNT
                     KNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLR
                     INSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLAL
                     QNEFADFVALVDKSQLAIQKSLEELETLKKSLMQEYFG"
     gene            30404..30640
                     /locus_tag="ACL8C7_001000"
     CDS             30404..30640
                     /locus_tag="ACL8C7_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HGS1395222.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLQSGEIIFTPEE
                     LGQQVSHVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            30637..31050
                     /locus_tag="ACL8C7_001001"
     CDS             30637..31050
                     /locus_tag="ACL8C7_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HGS1395223.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            31168..32133
                     /gene="xerA"
                     /locus_tag="ACL8C7_001002"
     CDS             31168..32133
                     /gene="xerA"
                     /locus_tag="ACL8C7_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008907 - integrase activity [Evidence
                     IEA];
                     GO_function: GO:0009037 - tyrosine-based site-specific
                     recombinase activity [Evidence IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase/integron
                     integrase"
                     /protein_id="HGS1395224.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            32099..32680
                     /locus_tag="ACL8C7_001003"
     CDS             32099..32680
                     /locus_tag="ACL8C7_001003"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS1395225.1"
                     /translation="MSSIHTKNSSLKSKSRFNEMFGDPLNNNKKFAVKTGQQCFKFSS
                     GKFLDKHDRVFEGYPAYGGNGIAWKSRKYLIDNPTIIIGRVGAYCGNVRTTHGKVWIS
                     DNAIYIKEFKNSDFNLVFLLELMKVIDFSKFADFSGQPKITQKPLENQKYILPPLALQ
                     NEFADFVALVDKSQFACEIAIKVWRNSLKFSII"
     gene            32710..36060
                     /locus_tag="ACL8C7_001004"
     CDS             32710..36060
                     /locus_tag="ACL8C7_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HGS1395226.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFVFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTTVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            complement(36646..37116)
                     /locus_tag="ACL8C7_001005"
     CDS             complement(36646..37116)
                     /locus_tag="ACL8C7_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGS1395227.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAKNDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(37133..39406)
                     /locus_tag="ACL8C7_001006"
     CDS             complement(37133..39406)
                     /locus_tag="ACL8C7_001006"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008239 - dipeptidyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HGS1395228.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            39753..42854
                     /locus_tag="ACL8C7_001007"
     CDS             39753..42854
                     /locus_tag="ACL8C7_001007"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HGS1395229.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDISLKLPRFNPARPAVEELRERAELGFVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVKKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLDLFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDSALEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSIEAGHTAEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNYSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKSIYIGLKSIKGLSKDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            42937..43944
                     /gene="pfkA"
                     /locus_tag="ACL8C7_001008"
     CDS             42937..43944
                     /gene="pfkA"
                     /locus_tag="ACL8C7_001008"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HGS1395230.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGGIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            44003..45508
                     /gene="pyk"
                     /locus_tag="ACL8C7_001009"
     CDS             44003..45508
                     /gene="pyk"
                     /locus_tag="ACL8C7_001009"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HGS1395231.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
BASE COUNT        14043 a         7991 c         9830 g        13733 t
ORIGIN      
        1 ttggtttccg cactcagggc aagatggggc gtcgtagtcc agtttggcga tgatttcctt
       61 gtgtgtatcc ttattgatga tgtctaaaat cttgatgttt gggtctttaa tgtctagtaa
      121 ttttgtgata aaatgtaatt gttccatatg aatctttcta atgagttgtt ttgtcgcttt
      181 tcattatagg tcatatggga cttttttcta caaaaaaata ggctccataa tatccatagg
      241 ggatttaccc actacaaata ttatagagcc caaaatcctt tgtttactaa acaagggatt
      301 tttcttttgt ctctgctcct tttttgatat aatagttcta tgttaaaatc agaaaaacaa
      361 tcacgttatc aaatgttaaa tgaagaattg tccttcctat tggaaggcga aaccaatgtt
      421 ttggctaatc tttccaacgc cagtgctctc ataaaatcac gttttcctaa taccgtattt
      481 gcaggctttt atttgttcga tggaaaggaa ttggttttag gtcccttcca aggaggtgtt
      541 tcctgcatcc gtattgcact aggcaagggt gtttgtggtg aggcagctca ctttcaggaa
      601 actgttattg ttggagatgt gacgacctat ctcaactata tttcttgtga tagtctagct
      661 aaaagtgaaa ttgtggtgcc gatgatgaag aatggtcagt tacttggagt tctggatctg
      721 gattcttcag agattgagga ttacgatgct atggatcgag attatttgga acaatttgtc
      781 gctattttgc ttgaaaagac agcatgggac tttacgatgt ttgaggaaaa atcttaatgt
      841 atcaagcact ttatcgaaaa tatagaagtc aaaacttctc ccagttagtt ggtcaagaag
      901 ttgtggctaa gactcttaaa caagcggtgg agcaagagaa aataagtcac gcttatcttt
      961 tttctggtcc tcgtggaacg ggaaaaacca gtgttgctaa aatctttgcc aaggctatga
     1021 actgtcccaa tcaagtgggt ggcgaacctt gcaataactg ctatatttgt caagcagtga
     1081 cggacggtag tttagaagat gtcattgaaa tggatgcagc ttctaataat ggggtagatg
     1141 aaattcgcga aattcgtgat aaatctacct atgcgcctag ccttgctcgt tataaggttt
     1201 atatcataga tgaggttcac atgctgtcta caggggcttt taatgccctc ctaaagacgc
     1261 tggaagaacc aacacagaat gtagtcttta ttttggccac tactgaattg cacaagattc
     1321 ctgctactat tctatcccgt gtgcaacgtt ttgagtttaa atcaattaag acacaggata
     1381 ttaaggaaca tattcactat atcttagaaa aagaaaatat cagttctgaa ccagaggctg
     1441 tggaaatcat tgccagacgg gcggaaggtg gaatgcggga cgccttgtct attttggatc
     1501 aagccctgag tttgacacag ggaaatgagc tgacgactgc tatctctgaa gaaattactg
     1561 gcaccattag cctatcaacc ttggatgatt atgtggcggc cttgtctcaa caggatgttc
     1621 ccaaagcttt gtcttgcttg aatcttcttt ttgacaatgg taagagcatg actcgttttg
     1681 tgaccgatct tttgcactat ttaagagact tgttaattgt tcaaacaggg ggagaaaata
     1741 ctcatcatag ttcagtcttt gtagaaaatt tggcacttcc tcaaaaaaat ctgtttgaaa
     1801 tgattcgctt agcaacagtg agtttagcag atattaagtc tagtttgcag cccaagattt
     1861 atgctgaaat gatgaccgtc cgtttggcgg aaatcaagcc cgaaccagct ctatcaggag
     1921 cggttgaaaa tgaaattgct acgctgagac aggaagttgc ccgtctcaaa caagagcttt
     1981 ctaatgcagg tgcggttcct aaacaagttg caccagctcc tagtcgacca gctacgggca
     2041 aaacagtcta tcgtgtcgat cgcaataaag tgcaatctat cttacaagag gccgtcgaaa
     2101 atcctgattt agcacgtcaa aatctaattc gtttgcagaa tgcctgggga gaggtaattg
     2161 aaagtctagg tgggccggac aaggctctgc tagttggttc tcaaccggtt gctgccaatg
     2221 aacaccatgc tattcttgct tttgagtcta acttcaatgc tggtcaaact atgaaacgag
     2281 acaatctcaa taccatgttt ggtaatatcc tcagtcaggc ggcaggtttt tcacctgaga
     2341 ttttagctat ttccatggag gaatggaaag aagttcgcgc agccttttca gccaaagcca
     2401 aatcttctca aactgaaaaa gaagtagaag aaagcctgat tccagaagga tttgaatttt
     2461 tggctgataa agtgaaggta gaggaagact aaagaaagat ttcatgatac aataagttta
     2521 tgaataaaca acaatttatt attatggcgc tatttacagc tgctgagacc tattttttca
     2581 atgaagcctg gatgactggc cgctatatta tggcagcctt ttgggcaatt ttactcttta
     2641 gaaatttccg agtcagttat gtgatgggta aaatcgttga tgtcatcgat cagcatttta
     2701 ataggaaaga ctagccctca gcttccagac aaaatcaaag ccttttaggc ttttttttgt
     2761 tatactagaa aagtatattt atagaatttt tgctctattt ctggggaaat cagacgtttt
     2821 tctagtaagt actgtaaaag ttttgaaaaa gaaaggaact atcatgtcag taatagagat
     2881 caaagatctt cacgttgaga ttgaaggaaa agaaatttta aaaggggtta acctgaccct
     2941 gaaaacagga gaaattgccg ctatcatggg accaaatggt acaggtaaat cgactctttc
     3001 tgccgctatc atgggaaatc caaactatga agtaactaaa ggtgaagttt tgtttgatgg
     3061 cgtaaacatc cttgagttgg aagtggatga gcgtgcgcgt atgggacttt tccttgctat
     3121 gcaataccca tcagaaatcc ctggaattac caatgctgag tttcttcgtg ccgctatgaa
     3181 tgcgggtaaa gaagatgatg agaagatttc agttcgtgag tttattacta agctagatga
     3241 aaaaatggaa ttgctcaaca tgaaagaaga aatggcagag cgttacctca acgaaggctt
     3301 ctctggtggt gagaaaaaac gcaatgaaat tcttcaactt ttgatgttgg agccaacatt
     3361 tgctcttttg gacgagattg actcaggtct tgatattgac gctcttaaag ttgtgtctaa
     3421 aggtgtcaat gccatgcgtg gtgaaggttt tggtgctatg atcatcactc actaccaacg
     3481 tcttttgaac tatatcacac ctgatgtggt acacgtgatg atggaaggtc gtgttgtcct
     3541 ttctggtggt ccagaattgg ctgcgcgttt ggaacgtgaa ggatacgcaa aattagctga
     3601 agaacttggc tacgactaca aggaagaatt gtaattccct cgtatctttt aggagaagta
     3661 aatgactaga gaaaatatta aacttttttc agaaatgcac gctgaaccaa gctggttggc
     3721 tgatctccgt caaaaagctt ttgacaagat tgagactttg gaattaccag ttattgagcg
     3781 tgtcaaattc caccgttgga atctgggtga tggaacgatt acagaaaatg agccatcagc
     3841 aaatgttcca gatttcacag ctttagatca tcacttgaag ttggtgcaag taggaactca
     3901 aactgttttc gaacaaactc cagttgagtt agctgaacag ggtgttgtct tcacagactt
     3961 tcactcagct ttagaagaaa ttccagagct gatcgaagaa ttcttcatgt catctgttaa
     4021 gtatgatgat gacaagttgg cggcttacca cacagcttac tttaacagtg gtgctgtact
     4081 ctatattcca gataacgtag aaattacaga gccaattgaa ggaattttct accaagatag
     4141 cgatagcaat gtgccgttta acaagcatat tatgattatc gctggtaaaa attctaagat
     4201 tagttatctg gagcgtttag agtcacgcgg tgaaggaagt gacaaagcaa ctgccaatat
     4261 cacagtggaa gtgattgcac gttctggtgc gcaagtcaag tttgctgcta tcgaccgtct
     4321 aggtgaaaac gtcactgcct acattagccg tcgtggtaaa ttaggcaacg atgcaagtat
     4381 tgactgggct atcggtgtca tgaacgaagg aaatgtcgtt gctgattttg atagtgactt
     4441 gattggtaat ggtagccatg ctgacctcaa ggttgtagct ctttcaagtg gtcgtcaggt
     4501 acaagggatt gatactcgtg taactaacta tggctgcaac tcaatcggaa acattctaca
     4561 acatggggtt atccttgaaa aagcaacttt gactttcaat ggtatcggcc acatcatcaa
     4621 gggtgctaag ggagcagatg cgcaacaaga gagccgtgtt ctcatgcttt cagaccaagc
     4681 gcgttcagat gctaacccaa ttcttttgat tgatgaaaat gacgtaactg caggacatgc
     4741 agcctctatt ggtcaggtag atccagaaga catgtattac ctcatgagtc gtggattgga
     4801 taaggcaact gcagagcgtt tggttgttcg tggtttcctt ggatctgtta tcgtggagat
     4861 tccagtcaag gaagttcgtg atgaaatgat tgcaactatc gaagagaaat tgtcaaaacg
     4921 ctaaggggaa gcctatgtta gatgtagaag cgattcgcaa ggattttcca attttagatc
     4981 agattgtcaa tgatgaacct ctggtctatc tggacaatgc tgcgacgaca caaaaaccac
     5041 tagtagttct gaaagctatt aacagctact atgagcagga caatgccaat gttcaccgtg
     5101 gtgtccatac cttagcggaa cgagcgacag cttcttatga agctgctcgt gaaaccattc
     5161 gtaagtttat taatgcaggc tctacaaagg aagttctctt taccagagga acgacaacca
     5221 gccttaactg ggtggcacgc tttgctgagg aaattctcgc tgagggagac caggtcttga
     5281 tttcagtaat ggaacaccat tctaatatca ttccatggca ggaagcttgt cgaaagactg
     5341 gagcagagct tgtctatgtc tatcttaaag acggtgcctt ggatatggag gatttgcgag
     5401 ctaaattgac tgataaggtt aaatttgttt ccctagctca tgcctccaat gttcttggtg
     5461 tggtcaatcc gatcaaggaa atcactcaat tagcccacca agttggggca attatggtag
     5521 tggatggtgc tcaatctaca cctcatatga agattgatgt ccaggacttg gatctggact
     5581 ttttcgcctt ttcgggtcac aagatggctg gtccgactgg tatcggtgtc ctttacggca
     5641 aagaaaagta tcttgagcaa atgtctccag tagaatttgg cggcgagatg attgattttg
     5701 tctacgagca atttgctagt tggaaggaat taccttggaa atttgaggct ggaacgccaa
     5761 atatggcagg agctattgga cttgcgactg cagttgatta tctggaaaag attggtatgg
     5821 atgccgttga agctcatgaa caggaattga ttgcgtacgt ctatccaaaa ctgcaggcaa
     5881 ttgagggatt gaccatttac ggttctcagg atttggctca acgttcgggt gttattgcct
     5941 ttaacctagg tgatctccat cctcacgatc ttgcgatggc tctggattat gaaggagtgg
     6001 ctgttcgtgc tggtcaccat tgtgcgcaac ccttgcttca gtatttggaa gtcccagcaa
     6061 cagctcgtgc aagtttttat atctacaata ccaaggcaga ttgcgacaaa ctagtcgatg
     6121 ccctacaaaa gacaaaggag tttttcaatg gcactttcta aactagatag cctttatatg
     6181 gcagtggtag cagaccattc gaaaaatcca catcaccaag ggaagttaga agatgctgag
     6241 caaatcagtc tcaacaatcc gacttgtggg gatgtcatca acctctctgt caagtttgat
     6301 gcagaggacc gtttggaaga tattgctttt ctaaattcag gatgcacgat ttcaactgct
     6361 tctgctagta tgatgacaga tgccgtttta ggaaaaacca aacaagaaat tttagaactg
     6421 gcgactattt tttctgaaat ggttcaaggg caaaaagatg agcgtcaagg ccaacttgga
     6481 gacgcggcat tcttgtcagg tgttgccaaa ttccctcaaa gaatcaagtg tgcaacccta
     6541 gcttggaatg cccttaagaa aacaattgaa aatcaagaaa aacagtagac aagtttcttt
     6601 tgtcttatga attattagaa atgaagaaag aaaggatact atggctgaag aaagagtaga
     6661 accaaaacca attgaccttg gtgaatataa atttggtttc catgacgatg tagagcctgt
     6721 cttatcgaca ggaaaaggac tcaacgaagg tgttattcgt gaattatctg ctgctaaggg
     6781 tgagcctgag tggatgttgg agttccgttt gaagtcttat gaaaccttca aaaaaatgcc
     6841 catgcaaact tggggagcag acttgtcaga gattgacttt gatgacttaa tctactacca
     6901 aaaaccatct gacaaaccag cccgttcttg ggatgatgta cctgaaaaga ttaaagaaac
     6961 ctttgaacgt atcgggattc cagaagctga acgtgcttat ttagcagggg cttctgccca
     7021 gtacgagtca gaagtggttt accacaacat gaaggaagag ttccaaaaat taggtattat
     7081 ctttacagat acagattccg cactcaagga atacccagac ttatttaaac aatactttgc
     7141 gaagttggta ccgccgacag ataacaagtt ggcagccctc aactcagcag tatggtcggg
     7201 tggaactttt atctacgtgc caaaaggtgt caaggtagat attccacttc aaacttattt
     7261 ccgtatcaat aacgaaaata taggtcagtt cgaacgtacc ttgattatcg ttgatgaggg
     7321 agcaagcgtc cactacgtag aaggatgtac agcaccaaca tattcaagca atagcttaca
     7381 cgctgccatt gtagaaattt ttgctttgga cggagcttat atgcgttata caactatcca
     7441 aaactggtct gataacgtct ataacttggt aacaaagcgt gctaaggctc aaaaggatgc
     7501 cactgttgag tggattgatg gaaacttggg tgccaaaacg actatgaaat atccatctgt
     7561 ttaccttgat ggagaaggag cgcgtggtac catgctctct atcgcctttg ctaatgcagg
     7621 gcaacaccaa gacacgggtg ctaagatgat tcacaatgct ccacatacca gctcgtctat
     7681 tgtgtctaaa tccatcgcta aaggtggagg aaaggttgac taccgtggac aagtcacctt
     7741 taacaagaac tctaagaaat ctgtttccca cattgaatgt gataccatta tcatggatga
     7801 cttgtcagca tcagatacta ttccatttaa tgaaattcac aactcgcaag tggctttgga
     7861 acacgaagcc aaagtatcta agatttcaga agagcaattg tattatctca tgagccgtgg
     7921 attgtcagaa tctgaggcaa ctgaaatgat tgtcatggga tttgtagaac cctttacaaa
     7981 agaacttcca atggaatacg cagttgagct gaaccgcttg attagctatg aaatggaggg
     8041 atcagttgga taaaatttga ttttatactc ttcgaaaatc tcttcaaacc acgtcagcat
     8101 cgccttaccg tatgtatggt tactgacttc gtcagtttca tctacaacct caaaacagtg
     8161 ttttgagcaa cctgcggcta gcttcctagt ttgttctttg attttgagta ttagatttac
     8221 tcaaaatcaa ggattttgaa gatgaacttg tatcaaaaaa tcgcggttta aaatcgcgat
     8281 tttttataat ttctcgttaa caaagcggac aaactgattc caccaaactt ttaagaagaa
     8341 ggctttttca attttcttgt ctgctaccat ttcgaaacta gggcgctctg tggtgatgta
     8401 accttgacca atcaagtcct tgtcttcata agtcaaatgg ccaaccactg ttccagcttc
     8461 aagtggtgct gggattgctt tggaatcagg tgtgaattga acagattggg aagattgatt
     8521 cccaacacgt tctattagat agatatcctc tggagccact gcagttactg tatcttcttt
     8581 tccatcttgt acaggggctt tgctatcttg ataggcatcg ccttgttgaa cgattttgcg
     8641 aagtgtaaat gtagaagaaa tataatccat tagggaagat gtagctgtaa atcgagcgta
     8701 aggattattg tcttgatgat ctgcatttaa aacaactgtg atgactctca tgcctttttc
     8761 gacagtagta ccaacaaaag actctccagc cttatctgtt gttcctgttt ttagcccatc
     8821 aaaaccacca cggtaagcag gcataccttc taacatgtag ttggttgaag tgattgtcat
     8881 cccagcaaaa gtagaagaag gttttttggt gatttctaag acttgtgggt attttttgat
     8941 gaggttgcga gcaacgatag cgacatcata agcactaagc ttattttcct catctttttt
     9001 agaacctggg taaatgttat cccctagagt ttcattgtta agacctgtcg tattgacaac
     9061 agtggcatcc tgaattcccc attccaagag ttttgcccgc atcatatcga cgaaatcttt
     9121 ttctgagcca gcaattttct cagctagggc aatagcggcg ctgttggcac tagataccag
     9181 agttgcttca agcaactctt cgacagtata attacgggcc tccataggaa tattactggc
     9241 ttcagaattt gtcgtcaatt gataaggata atcagaaata tctacaggag tggagagggt
     9301 aatacttccg ttttccaaag cttcatagac cagataaaca gtaatcaatt ttgttatgga
     9361 agcaatttcg acaggttgcg ttgcatcctt ctcatagaga attttaccag tatttgcctc
     9421 aacagcaatc gcatgtttag cggcaatggt aaaatcttga gcaacagcag tagaagcacc
     9481 ccctaaaaga gagacagtta ataaagttaa aaatattttt ttcatagtag tcttattcta
     9541 tcataaagaa aaaaaatatt cttgctttaa taattcatct gttaagcttt ttgaaaatat
     9601 ggtaaaataa agtaagggag gtaactcatg tttcgtagaa ataaattatt tttttggacc
     9661 acagaaattt tactcttaac catcatcttt tacctatgga gacagatggg gtctttggtt
     9721 aacccttttg ttagcgtgct taatacaatt atgattccat ttttattagg gggctttctt
     9781 tattatttga caaaccctat tgttactttc ttaaataaag tctgtaaact caatcgtttg
     9841 cttggtattt taattacctt gtgtactttg gtctggggaa tggtcatagg tgttgtctat
     9901 ctcttaccta ttttgattaa tcagttatct agtttgatta tatctagtca aactatttat
     9961 agtcgagtac aagacttaat catagactta tctaattatc ctgcgctcca gaatttggat
    10021 gtagaagcta caattcagca gttaaactta tcctatgtgg atattcttca aaatatccta
    10081 aatagcgtat caaatagtgt ggggagcgtc ttgtcagctc ttatcagtac tgttttgatt
    10141 ttgattatga ctccagtttt tttggtttat ttcttattag atggacataa attcttaccc
    10201 atgcttgaaa gaacgattct aaagagggat cgcttgcata ttgcaggctt attaaagaat
    10261 ttaaatgcga cgattgctcg ctatattagt ggagtttcga ttgacgcaat cattataggt
    10321 tgtttagctt atattggcta tagtattatt ggtttaaaat atgctttagt ttttgccatt
    10381 ttttctggtg tagccaattt aattccttat gtggggccaa gtattggttt gattcctatg
    10441 atcatcgcaa atatattcac tgatccccat agactgctga ttgcagtgat ttatatgctt
    10501 gttgttcagc aggtagatgg caatatctta tatcctcgaa tcgtaggaag tgttatgaag
    10561 gttcatccaa tcacgatttt agttttactt ttgttgtcaa gcaatatcta tggtgtagtt
    10621 ggaatgattg tcgcagtgcc aacctattct atcttgaaag aaatttctaa gttcttatcc
    10681 cgtttgtatg aaaatcataa aataatgaaa gaacgagaaa gagaattagc taagtaaaag
    10741 tcaggagaac cctgattttt ctttactgga agtggccttt agattagaag actgaaaata
    10801 agttaaagtc ttaaactaat tttcacagct aagaatagta gaagttaatc tgataaaaat
    10861 cgaaaaaacc agtggaattc cgtgtcaggg taagttccac tggttttcat agtctattaa
    10921 agttcgaatg aaacctattt atagtatatt gaaactagaa tagtacacct ctaattctaa
    10981 aacattgtta gaaatcgatt tgactgtcct gatctattca tcctattctt atttcatttt
    11041 actatatttt ggtgcaataa gtgaaaagta gtccgaataa tataaggatt aattttatag
    11101 tttttaaact caaatgaatt aaaataaaga gagtacgaaa attctcatct gaaagtattt
    11161 tagaataatt ctcttcgtga atttcttcaa aacagatagc ttcatcttag gtatgtgtta
    11221 attggatttc gtaagctcta tttacaatcg taaagttatg cactgagaaa gttgtagtta
    11281 gtcttccagt ttgctaaatt tctcgaatag tatctttttt aggtatgtga tttctttttg
    11341 catttttgag ttagataagg tataatggtt ttattgtctt ttggggtcgt tacggattcg
    11401 acaggcatta tgaggcatat tttgcgactc gtgtggcgac gtaaacgctc agttaaatat
    11461 aactgcaaaa aataacactt cttacgctct agctgcctaa aaaccagcag gcgtgacccg
    11521 atttggattg ctcgtgttca atgacaggtc ttattattag cgagatacga ttaagccttg
    11581 tctagcggct tgataagaga ttgatagact cgcagtttct aggcttgagt tatgtgtcga
    11641 ggggctgtta aaataataca taacctatgg ttgtagacaa atatgttggc aggtgtttgg
    11701 acgtgggttc gactcccacc ggctccatta ttcctttgca ttcttttgca ttccttggta
    11761 aaacgttgtt aaatcaacgt tttttatttt tatctttggt attcctttgc attcttttgc
    11821 taaaaaggga gtcacaaaca gaccctattt taaaaaagga tacaacattt gttgcatcct
    11881 aaaaataatc ttttttcgac ggaagacatg ggattcgaac ccacgcacgc tattacacgc
    11941 ctaccgcgtt tccaacacgg cctcttaagc ctcttgagta atcttccaat acttacttaa
    12001 atagtctacc ataaaggctc ttatcttgca ataaaaattc tagaaataag aaaaatgata
    12061 gattttgaaa gaaaatgata aaaaatgctt gacttcgaaa taaagtatgg tagaatgaat
    12121 agtgtaaacg ataacaggag gtgattcagt gttaaaaaca gaacgtaaac aactgatttt
    12181 agaggagtta aatcaacatc atgtagtttc tctagaaaaa ttagttagtt tgctagaaac
    12241 gtcagaatca acggttcgaa gagacttgga tgagttggaa gcggaaaaca agcttcgtcg
    12301 tgtgcatggt ggagcagaac tcccccactc cttacaggaa gaagaaacca ttcaagaaaa
    12361 atctgtcaaa aaccttcaag aaaagaagtt gctggctcag aaagcagcct ctctcattaa
    12421 agaaaaagat gtcatcttta tcgatgctgg aacaacaact gcttttttga ttcatgaatt
    12481 ggtcaataag aatgttacag ttgtgaccaa ctccattcac catgccgctc agttggttga
    12541 aaagcagatt ccaactgtca tggttggagg aaacgtcaag acggcgacag atgctagtat
    12601 cgggggcgtt gctcttaacc agattaacca attgcacttt gaccgtgcct ttatcggaat
    12661 gaatggtgtt gacgatggct attatacgac tcctgatatg gaggagggag ctgtgaaaag
    12721 agctattttg gagaatgcca agcagaccta cgtcttggtg gattcgtcaa aaattggaca
    12781 aacttgcttt gccaaggtag caccactcaa acgcgctatc gttatcacta gtcaagggca
    12841 tgagctcttg caggttatta aggagaaaac ggaggtaata gaagtatgat ttatacagtc
    12901 acactcaatc catccattga ctatatcgtt cgtttggacc aagtcaaagt tggtagtgta
    12961 aatcgtgtgg acagtgatga taagtttgct ggtgggaaag gaatcaatgt cagccgtgtc
    13021 ttgaaacgtt tgaatatacc aaatacagcg acgggattta tcggtggctt tactggtaaa
    13081 tttatcacag atactttagc agaggaagaa atcgagacac gttttgtcca ggtggcagaa
    13141 gatactcgta tcaatgttaa aatcaaagca gaccaagaaa cagaaatcaa cggaacgggt
    13201 ccaactgttg aaccggttca gctagaagaa ttgaaagcta ttttatctag tctgacagca
    13261 gaagatacag ttgtctttgc aggttcaagt gctaaaaatc taggcaatgt tatctataag
    13321 gatttgattt ccttgacgcg ccagactggt gcgcaagtgg tctgtgactt tgaaggacag
    13381 accttaattg atagtttgga ctaccagcct cttcttgtaa aaccaaacaa tcatgaactt
    13441 ggagcgattt ttggggttaa actcgaaagt ttagatgaaa ttgagaaata cgctcgtgag
    13501 ttactggcta agggtgctca aaatgttatt atctctatgg ctggtgatgg cgcccttctt
    13561 gtcacatctg agggagctta cttcgctaaa ccaatcaaag gaacagtcaa aaattcagtt
    13621 ggagctggtg attctatggt tgctggattc acaggtgaat ttgtcaaatc aaaagacgca
    13681 gtagaagcct tcaaatgggg agtggcttgc ggaacggcaa ctaccttctc agatgacttg
    13741 gcaacggcgg aatttattaa agaaacatat ggaaaagttg aggtagaaaa aagatgaaaa
    13801 ttcaagacct attgagaaaa gatgtcatgt tgctagattt gcaggcaact gaaaaaacag
    13861 ctgtcatcga cgagatgatt aaaaatttga cagagcacgg ttatgtaaca gattttgaaa
    13921 catttaaaga aggaattttg gcgcgtgaag ctttgacttc tactggtttg ggtgatggaa
    13981 tcgcaatgcc tcacagcaaa aacgctgctg tcaaagaagc gacagttcta tttgctaagt
    14041 caaataaggg tgttgactac gagagcttgg atggacaagc aactgacctc ttcttcatga
    14101 ttgcagctcc agaaggtgcc aatgatactc acttggcagc cttggcagaa ttgtctcaat
    14161 acttgatgaa agacggtttt gcagacaaac ttcgtcaagc aacatctgca gaccaagtta
    14221 tcgaactttt tgaccaagct tcagaaaaaa ctgaggaact tgttcaagca cttgctaatg
    14281 actctggtga ctttatcgta gctgttacag cttgtacaac aggtattgcc cacacttaca
    14341 tggcccaaga agcccttcaa aaagtagctg ctgaaatggg ggttggtatc aaggtcgaaa
    14401 ccaacggtgc tagcggtgtt ggaaatcaac taactgcaga agatatccgt aaggctaaag
    14461 ctattatcat tgcagcagac aaggccgttg aaatggatcg atttgatgga aaaccattga
    14521 tcaatcgtcc agttgctgac ggtatccgta agacagaaga gctaattaac ttggctcttt
    14581 caggagatac tgaagtctac cgtgccgcta atggtgcaaa agctgcaaca gcctctaacg
    14641 aaaaacaaag ccttggtggt gccttctaca aacacttgat gagtggtgta tctcaaatgt
    14701 taccattcgt tatcggtggt ggtatcatga ttgcccttgc cttcttgatt gacggtgctt
    14761 tgggtgttcc aaatgaaaac cttggcaatc ttggttctta ccatgagtta gcttctatgt
    14821 tcatgaaaat tggtggagct gcctttggtt tgatgcttcc agtctttgcg ggttatgttg
    14881 cctactctat tgctgaaaaa ccgggtttgg tagcaggttt cgtggctggt gctattgcca
    14941 aagaaggttt tgcctttggt aaaattcctt atgccgcagg tggtgaagca acttcaactc
    15001 ttgcaggtgt ctcatctggt ttcctaggtg cccttgttgg tggatttatc gcaggtgcct
    15061 tggttcttgc catcaagaaa tacgttaaag ttcctcgttc actcgaaggt gctaaatcaa
    15121 tccttctatt gccacttctt ggaacaatct tgacaggatt tgttatgcta gctgtgaata
    15181 tcccaatggc tgcaatcaac actgctatga atgacttcct aggcggtctt ggaggaggtt
    15241 cagctgtcct tcttggtatc gtccttggtg gaatgatggc tgttgacatg ggtggaccag
    15301 ttaataaagc agcttatgtc tttggtacag gtacgcttgc agcaactgtt tcttcaggtg
    15361 gttctgtagc catggcagca gttatggctg gaggaatggt gccaccactt gcaatctttg
    15421 tcgcaactct tcttttcaaa gataaattta ctaaggaaga acgtaactct ggtttgacaa
    15481 acatcatcat gggcttgtca tttatcactg agggagcgat tccatttggt gccgctgacc
    15541 cagctcgtgc gattccaagc ttcatccttg gttcagcagt agcaggtgga ctcgttggtc
    15601 ttactggtat caaactcatg gcgccacacg gaggaatctt cgttatcgcc cttacttcaa
    15661 atgctctcct ttacctcgtt tctgtcttgg taggagcaat cgtaagtggt gtggtttatg
    15721 gttacctacg caaaccacaa gcataaaaaa tagaaaaatg aaaagattgg accgtttggt
    15781 gcagtctttt tctcttcccg aaatgcctgt gaaatatggt ataatagaag aatggcaaac
    15841 aagaatacaa gtacaacaag acggagaccg tctaaagcag aactggaaag aaaagaagcg
    15901 attcaacgaa tgttgatttc gttaggaatt gcgattttat tgattttcgc agccttcaaa
    15961 ttaggggctg caggtataac cctttataat ttaattcgct tgctagtggg tagcctagct
    16021 tatctggcga tattcggcct attaatctat ctcttctttt tcaagtggat acgaaaacag
    16081 gaaggactct tatctggctt tttcaccata tttactggct tactcttgat ttttgaggcc
    16141 tacttggttt ggaaatatgg tttggacaag tccgttctaa aagggaccat ggctcaggtt
    16201 gtgacagatc tgactggttt tcgaacgact agctttgctg gagggggctt gatcggggtc
    16261 gctctttata ttccaacagc ctttctcttt tcaaatatcg gaacttactt tattggttct
    16321 atcttgattt tagtgggttc tctcctagtc agcccttggt ctgtttacga tattgctgaa
    16381 tttttcagta gaggctttgc caaatggtgg gaagggcacg agcgtcgaaa agaggaacgc
    16441 tttgtcaaac aagaagaaaa agctcgccaa aaggctgaga aagaggctag attagaacaa
    16501 gaagagactg aaaaagcctt actcgatttg cctcctgctg atatggaaac gggtgaaatt
    16561 ctgacagagg aagctgttca aaatcttcca cctattccag aagaaaagtg ggtggaacca
    16621 gaaatcatcc tgcctcaagc tgaacttaaa ttccctgaac aggaagatga ctcagatgac
    16681 gaagatgttc aggtcgattt ttcagccaaa gaagcccttg aatacaaact tccaagctta
    16741 caactctttg caccagataa accaaaagat cagtctaaag agaagaaaat tgtcagagaa
    16801 aatatcaaaa tcttagaagc aacctttgct agctttggta ttaaggtaac agttgaacgg
    16861 gccgaaattg ggccatcagt gaccaagtat gaagtcaagc cggctgttgg tgtaagggtc
    16921 aaccgcattt ccaatctatc agatgacctc gctctagcct tggctgccaa agatgtccga
    16981 attgaagcac caatccctgg gaaatcccta atcggaattg aagtgcccaa ctccgatatt
    17041 gccactgtat ctttccgaga actatgggaa caatcgcaaa cgaaagcaga aaatttcttg
    17101 gaaattcctt tagggaaggc tgttaatgga accgcaagag cttttgacct ttctaaaatg
    17161 ccccacttgc tagttgcagg ttcaacgggt tcagggaagt cagtagcagt taacggcatt
    17221 attgctagca ttctcatgaa ggcgagacca gatcaagtta aatttatgat ggtcgatccc
    17281 aagatggttg agttatctgt ttacaatgat attccccacc tcttgattcc agtcgtgacc
    17341 aatccacgta aagccagcaa ggctctgcaa aaggttgtgg atgaaatgga aaaccgttat
    17401 gaactctttg ccaaggtggg agttcggaat attgcaggtt ttaatgccaa ggtagaagag
    17461 ttcaattccc agtctgagta caagcaaatt ccgctaccat tcattgtcgt gattgtggat
    17521 gagttggctg acctcatgat ggtggccagc aaggaagtgg aagatgctat catccgtctt
    17581 gggcagaagg cgcgtgctgc aggtatccac atgattcttg caactcagcg tccatctgtt
    17641 gatgtcatct ctggtttgat taaggccaat gttccatctc gtgtagcatt tgcggtttca
    17701 tcaggaacag actcccgtac gattttggat gaaaatggag cagaaaaact tcttggtcga
    17761 ggagacatgc tctttaaacc gattgatgaa aatcatccag ttcgtctcca aggctccttt
    17821 atctcggatg acgatgttga gcgcattgtg aacttcatca agactcaggc agatgcagac
    17881 tacgatgaga gttttgatcc aggtgaggtt tctgaaaatg aaggagaatt ttcggatgga
    17941 gatgctggtg gtgatccgct ttttgaagaa gctaagtctt tggttatcga aacacagaaa
    18001 gccagtgcat ccatgattca gcgtcgtttg tcagttggat ttaaccgtgc gacccgtctc
    18061 atggaagagc ttgagatggc aggtgtcatt ggtccagctg aaggtaccaa accaagaaaa
    18121 gttttacaac aataaaaaaa tagcttcttt ccaagtttgg aaggaggcta ttttagtgat
    18181 tattgattag ttttattttc cgaagttggg gtattggact gtttttcgtt ttcagtagca
    18241 ggtttacttg gagtaggagc aggagtagaa gaatcctgag ttgatgtttt ctgctcttct
    18301 tttttctctt ccttgacgct ggattttggc gtttcttctt gttgtgtttt ttcttgagaa
    18361 gtcttatttt ccttattggg actagtattt tcctgagggg attccttttg aatttctttg
    18421 acaattgttg tcgtctggct tgttgtaggt tcctttttag tatttttgtt attatccaag
    18481 gcgttcataa tcgtgatact agcggtaatc aagccaagga tactagcgat agtcgcaacg
    18541 gttttttgaa agactgtaaa gccttttttg atgtgttctg tttttggttt tgaagttcta
    18601 cgataattag acatacattc tctcctttaa ttaaaattta ttatacctca tttctttaaa
    18661 aaaatcttaa aaaaagagga gatttttcta cacgaacttc agtaattagt tgaaataaaa
    18721 tatgacttat gatataacaa aataaagaaa gcgatttcaa aaaaggaggg cgttatatgt
    18781 tcgaaattag aaatttgagt ctctcttttg caggcaggcg gttgctagag ccaacagatt
    18841 tgatatttga aaggggaaaa gtatatacaa tatatgggaa gtcaggcgta ggaaagtctt
    18901 ctttactgaa taaaattggt ttgctctctg ctacgtatcc tagtgtttct tatttcttcg
    18961 atggaaaaga gattgatatc gaaaataaga aatcagtctc tgtctttata gctgaagaag
    19021 ttgcctttgt atttcagggg cgaaatctaa taaatgattt gaccgtattt gaaaatttaa
    19081 gactagcttt aaacttttat gacttgagtc cagatgaaat agaaagcaaa attgatacag
    19141 tattggcgga tttacagatt tcttctttaa agcatgctta tccagaagat ttatccggtg
    19201 gtgaagaaca acgagtggca atcgcaagag ccttagttac aggaaagact ctcatcttag
    19261 ctgatgaacc aacaagttct ttggataaag aaaatagaga aaaagtctcc gccttgttaa
    19321 ttgatttagc tcacaaatat cataaaattg tattgattgt ttcgcatgat gaggcgatga
    19381 ttgcaatagg agatgttcag cttcatttta aagaccataa attagttggg aattgtctta
    19441 ttttgaattc tgatgaaggg ataaaggatt ctaagaagtg gtcctcctgt ttgtcgtctt
    19501 ctcatacgaa gctatccgtt ttgaaacata gaaggccttt tttacctaga ttattagcgt
    19561 tttttatctc tcttgtagtt gctatagcag taacctctat taactttcag tccttatttg
    19621 cagataagta tcaccaactg gtgaacaact cactcgaaaa tggcttcttg gtgattaatg
    19681 attcgcttca tttacaaact acaaaagtgt tggatgattt tctcagtttt gataaggagg
    19741 aaatcacctc aattagcaca agtcagaata ttcaaaccgt caatccttat atagagtttc
    19801 tctctttggg tatgacgttt gataattcaa aagactattc acaacttcaa aagaactttc
    19861 agccaacttt gactattgat ggtcagacca gaagcttgac aagaaatttt tcaattcaac
    19921 ccttgtatca gacaaataca acacagaggc agatagagta ttttgatagg agcaatgaaa
    19981 aagggattta tctatctgag caattcattt cagatgaaaa attaccaaat atagtttcgg
    20041 gaactaccgt gacactgact ttttatattc caatttcttt atatgaatca agtatagaga
    20101 aagaggggaa tatattgaaa ggagatggcg atttatttgt caaagtggat aaaacatatc
    20161 ctgttttagg gattgttaaa aaaagttatc cgtttgaata ttccccttat gggaacaccc
    20221 tatttatgaa tattgctgaa atggaagaat tgcaaaatga agcaattcaa cagcatccca
    20281 tgacgaagat ggctttagat ggttttcctt tgaaatcatg gatgccgagt gcgattcatg
    20341 tgttactaaa ggatagcggt gctattcctg aagaattgag tagaataaga gcaatctctt
    20401 cacaaattac tattttatca tcatatgaaa actacgaaga atttaataaa ggactcacct
    20461 atatcaggca atttttaatg ttgctatccc tagtcttact catccttgtc attgcagtat
    20521 tgtcctttgt tttctttttg ctcaatcgtc ctcgacgctt tgaagtaggg attttaaaat
    20581 ctttgggata cagtactcaa aatattgttt ggcttttctt aaaagaatta attggttatg
    20641 gtaaaacaat ttcgatatta gcaagttgtt tactcgtcat tctttccatt ttagcaatgc
    20701 aagtgcttaa attggaaatt tcagatgttt ttaaattcta tctaacttcc gttttcacct
    20761 taattggatt atcagtctca gtactgataa taagtggctt actacctata tacacaactt
    20821 gtaggcaaac agttgtcgat actatccgaa agaatggatg aggtgatatc atgaaacata
    20881 agataatgaa aaaaataata gtggtagtgt ttgctatccc atggttaaca tttttaagtc
    20941 aagtacatgc agattatgta agtaagtcta gttctttaga cggttatagc ttggtaggct
    21001 tgaatgttct taatgtgact tttaatgctt ctggctattc tgatacttat agtggcagtg
    21061 tgtcaaatat gtatttcact gactgggctt ggtttcctaa tacgataagt aatcgttcca
    21121 cttggaaaag ttcgattcca tatggccaac gcgcaaatgg tacagtccat atagatgtag
    21181 gagtaaattc gccttgggga gcggttaatc tctggggcgg acaaaattac ttttctttag
    21241 atttttaaca gaaataatca aagttagata gaatgaataa gaatgctctt gatgatggta
    21301 tcaagagtat tttatgttat tcagattaat gcaaacattg ccctttcttg tcgcaggctc
    21361 cgtttcatga tacaatagaa ggagtgattt tagaaagcgt gagaaacatg atttactttg
    21421 ataattcggc gacgaccagg ccctatccag aagcccttga aacctatatg caggtggctt
    21481 caaaaatttt aggaaatcca tctagtctcc atcgtttggg agaccaggca acacgaattt
    21541 tagatgcttc ccgtcaacag attgcagatt taatcggtaa gaaaagtgat gaaatcttct
    21601 ttacatctgg tgggacagaa ggggataact ggatcatcaa gggagtagca tttgaaaaag
    21661 cccagtttgg caagcacatc atcgtatcag ccattgaaca tccagcagtt aaggaatcag
    21721 ccctctggtt gaaagctcaa ggttttgaag tggattttgc tccagttgat aacaaaggat
    21781 ttgtggatgt tgaggcgcta gaagatttga taagacctga tacgaccctc gtttccatca
    21841 tggcagttaa caatgaaatt ggctctgttc agcccattga ggctatttca aaactattgg
    21901 cagacaagcc aactatttcc ttccacgttg atgcggttca ggcgcttgcc aagattccga
    21961 ctgaaaagta tctgacagaa cgagtggatt tcgcgacttt ctctggtcac aagttccacg
    22021 gaatccgtgg tgttggtttt atctatatca agtctggcaa gaagattacg cctcttttaa
    22081 caggtggtgg tcaggaacgt gattaccgtt cgacaactga aaatgtggca ggaattgcag
    22141 cgaccgctaa ggctctccgt ttatctatgg aaaagctaga tatctttagg agcaagactg
    22201 ggcagatgaa ggcagtgatt cgtcaagcac ttctggacta tccggatata tttgtctttt
    22261 cagatgagga agacttcgcc cctcatattc tgacttttgg aatcaagggt gttcgtggtg
    22321 aggtcattgt tcacgccttt gaagactatg atattttcat ctcaacgacc tcggcttgtt
    22381 cgtccaaggc tgggaaacca gccggaaccc tgattgctat gggagtggac aaggataagg
    22441 ctcagtcagc tgtgcgtctt agtctagacc ttgaaaatga tatgagtcag gtcgagcagt
    22501 tcttgaccaa gctaaaatta atttacaatc aaactagaaa agtaagatag gagcattcat
    22561 gcagtattca gaaattatga ttcgctacgg tgagctgtca accaagggca aaaatcgtat
    22621 gcgtttcatc aataaacttc gcaataatat ttcagacgtt ttgtctatct atccccaagt
    22681 taaggtaaca gcagatcgcg accgtgccca cgcttacctc aatggagcag attacacagc
    22741 agtagcagaa tcgctcaaac aagtatttgg aattcaaaac ttttcccctg tttataaggt
    22801 tgaaaaatct gtagaagttc tgaagtctgc tgtccaagag attatgcagg acatctacaa
    22861 ggaaggcatg acctttaaaa tctctagcaa gcgtagcgac cacacctttg aattggacag
    22921 tcgtgaactc aaccaaacgc ttggaggggc tgtattcgaa gccattccaa acgtacaagc
    22981 tcaaatgaaa agtcctgaca tcaatcttca ggtggagata cgtgaagaag cagcctatct
    23041 ttcttatgaa accgttcgag gggcaggtgg attaccagtg ggaacttctg gtaagggcat
    23101 gctcatgttg tcagggggaa tcgattcccc tgtagctggc tatctagcgc ttaaacgagg
    23161 ggtagatata gaggcagttc actttgccag cccaccttac acgagtcctg gtgctcttaa
    23221 aaaagcccaa gatttgaccc gtaaattaac caaatttggg ggaaatatcc agtttatcga
    23281 agttcctttt acagagattc aagaggaaat caaagccaaa gcgccagaag cctaccttat
    23341 gaccttgacg cgtcgtttta tgatgcgtat tactgaccgt attcgtgagg tacgaaatgg
    23401 tttggttatc atcaatgggg aaagtctagg tcaagtagcc agccaaaccc ttgaaagtat
    23461 gaaggctatc aatgctgtta ccaacactcc catcattcgt cctgtggtta ccatggacaa
    23521 gttggaaatc attgacatcg cccaggaaat cgataccttt gacatttcaa tccaaccgtt
    23581 tgaagactgt tgtaccattt ttgcaccaga tcgtccaaaa acaaatccta aaattaagaa
    23641 tgcggagcag tacgaagcgc gtatggatgt tgaaggcttg gttgagcgag cagtggctgg
    23701 aatcatgatt actgaaatca cacctcaagc cgaaaaagat gaagttgatg acttgattga
    23761 taatctactc taattcagaa aatccaaaag aatagcgaaa atcagtaaaa aaagttagtt
    23821 ttttttctaa aaacaggtaa aaaactaact tttttctatt ttcatgatat aatgatataa
    23881 aattttgaat atagagagtt ttctgacaat gaatcaatcc tacttttatc taaaaatgaa
    23941 agaacacaaa ctcaaggttc cttatacagg taaggagcgc cgtgtacgta ttcttcttcc
    24001 taaagattat gagaaagata cagaccgttc ctatcctgtt gtatactttc atgacgggca
    24061 aaatgttttt tatagcaaag agtctttcat tggatattca tggaagatta tcccagctat
    24121 caaacgaaat ccggatatca gtcgcatgat tgtcgttgct attgacaatg atggtatggg
    24181 gcgaatgaat gagtatgcgg cttggaagtt ccaagaatct cctatcccag agcagcagtt
    24241 tggtggtaag ggtgtggagt atgctgagtt tgtcatggag gtggtcaagc cttttatcga
    24301 tgagacctat cgtacaaaag cagactgcca gcatacggct atgattggtt cctcactagg
    24361 aggcaatatt acccagttta tcggtttgga ataccaagac caaattggtt gcttgggcgt
    24421 tttttcatct gcaaactggc tccaccaaga agcctttaac cgctatatcg agtgccagaa
    24481 actatcgcct gaccagcgca tcttcatcta tgtaggaaca gaagaagcag atgatacaga
    24541 caagaccttg atggatggca atatcaaaca agcctatatc gactcgtcgc tttgctatta
    24601 ccatgatttg atagcagggg gagtacatct ggataatctt gtgctaaaag ttcagtctgg
    24661 tgccatccat agtgaaatcc cttggtcaga aaatctacca gattgtctga gattttttgc
    24721 agaaaaatgg taagttaaga aaggaaaaaa cgaaatgcat attgaacatc ttagccactg
    24781 gagtggtcat cctaaccgtg aaatgtacct taaccgttat ggacatggtg ggattccagt
    24841 tgtggtcttt gcttcatcag gtagtagtca caacgaatac tatgattttg gcatgattga
    24901 tgcctgtgct tcctttatcg aggaaggccg tgtccagttc tttaccctat ctagtttgga
    24961 tagtgagagc tggttggcta cttggaaaaa tgctcatgac caagcggaaa tgcaccgtgc
    25021 ctacgaatgt tatgtgattg aggaggccat tcttttatca agcacaagac aggttggttt
    25081 gatggcatga tgacgacagg ttgctctatg ggagcctatc atgcactcaa tttcttcctc
    25141 cagcatccag atgtctttac caaagtgatt gctctcagtg gtgtttacga cgcacgtttc
    25201 tttgtcggtg attactacaa cgatgatgct atttaccaaa actcgccagt agattatatt
    25261 tggaaccaaa acgacggctg gtttattgac cgttaccgtc aggcagagat tgtgctgtgt
    25321 acggggcttg gagcctggga acaagatggt ttgccatcct tttacaagct caaagaagcc
    25381 tttgacaaga aacaaattcc agcctggttt gctgaatggg gacatgatgt agcccatgac
    25441 tgggaatggt ggcgtaaaca aatgccttat ttcctcggta atctctattt ataaaaggag
    25501 ttacctatga attaccttgt tatttctccc tactatccac aaaactttca acagtttacc
    25561 atcgaactag ctaataaagg catcacagtc ttgggaattg gtcaagagtc ttacgagcaa
    25621 ttggatgagc ccttgcgcaa tagcttgacc gagtattttc gtgttgataa tcttgagaac
    25681 atagatgaag tcaaacgtgc agttgctttt ctcttttata aacatggtcc aattgaccgc
    25741 atcgagtctc acaatgaata ctggcttgag ctagacgcaa cactcagaga acaattcaat
    25801 gtttttggtg ccaaaccaga ggatctcaaa aagacgaaat ataagtctga aatgaagaaa
    25861 cttttcaaaa aagcaggtgt tcctgtggta cctggagctg ttatcaagac ggaagcagat
    25921 gttgatcaag cagtgaaaga aatcggtctt ccaatgattg ccaaacctga taatggagtg
    25981 ggagcagccg caacctttaa acttgagaca gaagacgata tcaatcactt caagcaagaa
    26041 tgggaccatt caacccttta tttctttgaa aaatttgtca cttccagcga aatctgtacc
    26101 tttgacgggc tcgtggacaa ggatggaaag attgtcttct caacaacctt tgactacgcc
    26161 tatacaccgc ttgacctcat gatttataag atggacaatt cctactatgt gctcaaggat
    26221 atggttccca aactacgcaa gtatggggaa gcgattgtta aggaatttgg tatgaaagaa
    26281 cggtttttcc atattgagtt cttccgtgag ggggacgatt atattaccat tgagtacaat
    26341 aaccgccctg caggtggttt caccattgat gtttataact ttgctcattc cttggacctc
    26401 tatcgtggat atgcagccat tgtcgcagga gaagagttcc cagcgtcaga gtttgaacct
    26461 cagtattgtt tggctacatc acgtcgtgca aatgctcact atgtctattc tgaggagaac
    26521 ttacttgcca aatatagcca gcagttcaag gttaaaaaaa tcatgccaga ggcttttgcg
    26581 gaacttcaag gagattactt ttatatgctg acaactccga gtcgacaaga aatggatcag
    26641 atgattgctg atttcggaca acgtcaagaa taagaactat cggattaagg aaattcactc
    26701 ccttaatcct tttgttttgt ctggtaaaaa ataagagcat cctaacaagg tagctatcat
    26761 aaaacttgtt cgataactat ttgaagcagg attaggtggt tagaaattga attttaacat
    26821 ttcaattgag tcatagtatt gtgttttcgt atccttaaat cagctaaaag gatccatgac
    26881 gacacctata cgatatagtt ttcaggatac caaacaagtc tattaatact caatgaaaat
    26941 caaagagcaa actaggaagc tagccgcagg ttgctcaaaa cactgttttg aggttgtgga
    27001 tagaactgac agagtcagta tcatatacct acggcaaggt gaagctgacg tggtttgaag
    27061 agattttcga agagtataaa atattcaggt gacgcataga tatagttaat tgaagctttg
    27121 tttgaaatct gataaaataa tgatattact aagttttaaa aactaaagaa aagggaagat
    27181 atgattacag gcgaattaaa aaataaaatc gatcagctgt gggaaattct ttggacagaa
    27241 ggaaacgcaa atcctttaac aaatattgaa cagttgactt atctcttatt tatgaaagat
    27301 ttggatagtg tcgagcttgg acgtgaaagt gatgctgaat ttctagggat tccttatgag
    27361 ggagtttttc caaaagataa acctgaatac cgttggtcaa cttttaaaaa tataggagat
    27421 gctcaggaag tttatcgttt aatgactcag gagatttttc cgtttattaa aaatctcaag
    27481 ggggatacag atgatacagc cttttcacga tatatgcgag aagctatttt tcaaataaat
    27541 aaacctgcta cgcttcaaaa ggcaatttct atcttagatg tttttccaac taggggatta
    27601 gatgtagatt ttgataatga caaacaaagt attactgata tcggagatat ctatgaatat
    27661 ctgttatcaa aattgtcgac cgcaggtaaa aatggacagt tccgtacacc tcgtcacatc
    27721 atcgatatga tggttgagtt gatgcaaccg actatcaaag atatcatctc agatcccgct
    27781 atgggttctg ctggcttctt agtatctgct agccgttact taaagcgtaa gaaagatgaa
    27841 tgggaaacca atacagataa tatcaatcat tttcataatc agatgtttca tggaaatgat
    27901 acggatacga ctatgttgag acttggggcg atgaacatga tgctacatgg agtagaaaat
    27961 ccacaaatca gttaccttga ctcgctgtct caagataatg aagaagccga taaatatact
    28021 ttggttttag caaatcctcc ttttaagggc tcacttgact acaattcaac ctctaatgac
    28081 cttcttgcaa ccgtaaaaac caaaaaaaca gaattactct ttctttctct tttcttgcga
    28141 actttaaaac caggtggacg agcagcagtt atcgtacctg atggtgtcct ttttggttcg
    28201 tctaaagctc ataaaggaat tcgtcaggaa attgtagaga atcataagct tgatgctgta
    28261 atctcaatgc ctagtggtgt tttcaagcct tatgctggag tttcaactgc cattctcatc
    28321 tttacaaaaa ctggtaatgg tgctactgac aaagtctggt tttacgatat gaaagcggat
    28381 ggtttaagtt tggatgataa gcgacaaccg attagcgaca atgatattcc agatattatc
    28441 gaacgctttc atcatcttga aaaagaagca gaacgtcaga gaacggatca atctttcttt
    28501 gttccagttg ctgagataaa ggaaaatgat tatgatttgt ctatcaataa atataaagag
    28561 attgagtatg aaaaagttga gtatgaacca acagaggtca tcttaaagaa aatcaatgat
    28621 ttagaaaaag aaattcaagc tggcttggct gaattggaaa aattactcaa gtagggaggt
    28681 ggctgtatga aaaaagtgaa gttgggggaa atcttatctc taaaaaaagg aaagaaagcc
    28741 actgtacttg ctgaacaaac aactctaagc caacgttata ttcaaataga tgatttaaga
    28801 aataataata atttaaaatt cactgaaagt ttaaatatga ctgaagcact cccagatgat
    28861 attctaatag catgggatgg tgctaatgca ggaacagttg gctatgggtt atcgggagct
    28921 gttggtagta caattacggt cttaaaaaag aatgagcgat acaaagaaaa aattatatca
    28981 gattacttgg gagtcttttt ggaaagtaaa tcgcagtatt tacgagatca ttcaacaggt
    29041 gcaactattc ctcatttaaa caagaatata ttacttgatt tacaattaga attgctaggt
    29101 atcgaagaac aagagaacat tatctgtatt cttaatacga ttaaaaggct tattactaaa
    29161 agaaaatttc agttagatga actaaacttg ctcgtcaaat cccgatattc cgaggaggtg
    29221 gttgcatgaa gaaagtgaaa ttagggcaag tggctacttt tatcaatggc tatgctttta
    29281 aacctcaaga ttggtcatct gaagggaaag agattatcag aatacagaat ctgactaaaa
    29341 cttcaaaagg gataaattat tattcgggta cgattgataa aaaatacatt gttgaagctg
    29401 gtgatattct tatttcgtgg tcgggtacat taggggtttt tcagtggtgt ggaagatccg
    29461 cagtgttaaa tcagcacatt tttaaagtgg tttttgataa gatagatata gataaatcgt
    29521 attttaaata tgttgttgaa aaaggtttac aagatgctgt aaaacatact catggttcca
    29581 caatgaaaca tttaactaaa aaatattttg ataatattat agttccatat acaaatttgg
    29641 gagagcaaca aagaattgca agtgagctgg atttgttaag caagctgatt ttaaggagac
    29701 aagaacaact tgaagagctt aatctacttg taaaatcccg atttaacgag atgtttgggg
    29761 aaaataaaat atttgaaagc attgataact tatttgatat tatagatggt gataggggca
    29821 aaaattatcc taaatcagat gagttgttta gtgaggagta ctgtttattt ttaaatacaa
    29881 agaatgttac taaaaacgga ttttcattcg atacaaagca atttatcact aaaacaaagg
    29941 ataaattact tcgaaaaggc aaacttgagc gttatgatat agtcttgaca acaagaggta
    30001 ctgttggaaa tgtagcgtac tacgatgaat taataaaata taaacattta cgtataaatt
    30061 caggtatggt aatattacgt cccaagacac caaatctaaa tcagaaattt attatccatg
    30121 ttttaaggaa taataattat agtcgagtga tatcaggaag tgctcagcct cagttaccaa
    30181 ttacaaaatt aaaaaaaata cttctccccc tccccccact agccctccaa aatgagttcg
    30241 cagactttgt agccctggtc gacaaatcac aattggcaat ccaaaaatct ctggaagaac
    30301 ttgaaacttt gaagaaatct ctgatgcagg agtattttgg ctgatattct gtcattgtaa
    30361 ttacggtaat gatttgttat aatacttcaa aggaggaaat cagatggtag taaaaacaag
    30421 aaaacaagga aattcaatca ccattacgat tccaagtgaa tttaatattc caagtggtgt
    30481 taaatacgaa gcgaaattgt tacaaagtgg tgagattatc tttactcctg aagaattggg
    30541 gcagcaggtt tctcatgtat ctgatgatgc ctttgactta aatttagata aaatatttga
    30601 cgaatacgac gatgttttca aagctttggt ggaaaaatga caatctatct gacagaaaag
    30661 caaattgaaa aaataaatgc tttagcaatt caacggtatt ctccaaatga gaaaattcaa
    30721 acagttagtt cttctgcctt aaatatgatt gtgaacttac cagaacaatt tgtctttggg
    30781 aagtctcttt atccaacaat ttttgataaa gcaacgatac tatttgtcca attgataaag
    30841 aagcatgttt ttgctaatgc taataaaaga actgctttct tcgttttggt caaattttta
    30901 caattaaacg gctatcgttt ttctgtaacg gtagaagaag cagtaaaaat gtgtgtaacc
    30961 atcgcagtag aagctttaac tgatgaaaaa atgacaagct attccaaatg ggtttctgaa
    31021 cattctgtta gagaaaaggt caaaaagtaa cctagtatgc tggatttgaa tgagcacaag
    31081 aaaataaatg aacagacaat attagaattc tgtaatgcag aaactgatat tgtctctttt
    31141 tattgatgaa taagaaagtg agaaattatg gaatcaaaag ttacaattat catgcaagaa
    31201 atgttacctc ttttaaataa tgaacaatta ctagcgttga gagagagttt agaacatcat
    31261 ctagtagacg gaaaaaagca gcagaagtat tcgaataata acctgttgca actatttatt
    31321 accgccaagc aggtagaggg ctgtagctca aaaacaattc gttattacca gaggacgatt
    31381 gaaaacttgt ttaatgctat taaagagtct gtgacacaac tcacaacaga tgatttaagg
    31441 agttatttag caaattacca gtctgaaaag gattgtagta aggcaaattt agacaatatt
    31501 aggcgtatat tgtcttcttt ttttgcttgg cttgagcaag aggaatatat cattaaaaat
    31561 cccattcgac ggataaagaa aattaagact gagcaaaatg tgaaggaaac ttatactgat
    31621 gaacatttgg aaattatgcg tgataactgt gaaaatttga gagatttggc aataatagac
    31681 ctactagcat cgacaggtat gcgtgtaggg gagcttgtac agttgaatcg ttcagatatt
    31741 gattttgaaa acagagagtg tgttgtcttt ggtaaaggaa agaaggagag accagtatat
    31801 tttgatgctc ggacgaaaat tcatttaaga aattatctta acgacagaaa agatagtcac
    31861 cctgctcttt ttgtaacgct agttggaaaa gcccagagac ttggaattgc tggtgtagag
    31921 attcgcttaa gaaagttagg agacaaactc ggcatacaaa aggttcaccc acataagttc
    31981 agaagaactt tagcgactaa ggcaattgat aaaggtatgc ctatcgaaca agtccaaaaa
    32041 ctgctaggtc atagcaagat tgacacaacc ctggcctatg ccatggtcaa tcaaaataat
    32101 gtcaagcatt cacaccaaaa attcatctct taaaagcaaa tcccgattta acgagatgtt
    32161 tggggatcct ttaaataata acaagaaatt tgcagtaaaa acgggacaac agtgttttaa
    32221 attttcaagt ggaaaatttc ttgataaaca tgatagagtt tttgaaggtt atcctgccta
    32281 tggtggaaat ggcattgctt ggaaaagtcg aaaatattta attgataatc ctactatcat
    32341 cattggtcgt gtaggtgcat attgtggtaa tgtaagaact acccacggta aggtatggat
    32401 aagtgacaat gctatatata taaaagaatt taagaattcc gatttcaatc ttgtattttt
    32461 attagaatta atgaaagtaa ttgattttag taaatttgct gatttctcag gtcaaccaaa
    32521 gataactcaa aaaccattag aaaatcagaa atatatcctc cccccactag ccctccaaaa
    32581 tgagttcgca gactttgtag ccctggtcga caaatcacaa tttgcttgtg agatagctat
    32641 aaaagtgtgg agaaatagct tgaaatttag tataatatag ctaaactatt tgtttaaagt
    32701 gagaaaaaaa tgggaaattt tagctttctt ttaaaaaatg acgaatatga atctttttca
    32761 aaaccttgca ttgaagctga aaatatgatt gctacatcaa ctgtggctac tgcctttatg
    32821 gcccgtcgtg ctttagagca ggctgtccat tggatatata gtcacgattc atatttagaa
    32881 gctccctatc gtgctactct atcttcttta gtatgggatg atgattttag ggatatcgta
    32941 gattctgaac tccacaagca gatagttctg ttgattcggt ggggaaacca tgctgctcat
    33001 ggtggtgaaa ttaaggaacg agaagcgatt ttagctttac atcatttgta tcagtttgtt
    33061 aattttatcg attattgtta cagcaatgaa tttgtggagc gttattttga tgagaagtgc
    33121 ttaccacttt cagcaaacat caaataccga gaaactccac aatctatgat aaagttacaa
    33181 gacagtttac cagaactgcc tgattttcat gaacagatgg ctgctcagtc cgtagaagtt
    33241 caagagactt atactgaaaa acgtgagact gcagcgcaac ggcaagatgt gcctttccat
    33301 attgatcaat tatctgaggc agagacaaga aagctcttta ttgatatcga tctccgttta
    33361 gcaggatgga tatttgaaga aaactgtcgt gttgagatag ccgttgatgg tctcaagcac
    33421 ggttcaggaa ttggttactg tgactatgta ctttatggta aaaatgggaa aattttagcg
    33481 attgtagagg ctaaaaaagc ctctgtcaat ccagaagtag gggaagtaca ggtcaaagaa
    33541 tatgctgaag ctcttgagaa acatatcggc tatcagccaa tttgctttat tacaaatggc
    33601 ttgaagcact atatacttga tggtccgaac cgccgccaga ttgcaggctt ttactctcaa
    33661 gaagaattgc aattagtgat ggatagacgt catcttcaaa aaccacttga ggatatttct
    33721 agtaaaatta gggacgatat ttccgggcgt cactaccaaa aacacgcgat tgcaagcgtt
    33781 tgtgaagctt tctctaatca tcgtagacag gcacttttgg ttatggcaac tggggctggg
    33841 aaaactcgta cagcagtttc tctagttgat atcttatcac gtcataactg ggtaaaaaac
    33901 gttctcttct tagccgatag aacttccttg gttaagcaag cctatgattc gtttagaaaa
    33961 ttactcccag atctttccgt ttgtaacttc ttagaagata aagaaggagc tcaatcaagt
    34021 cgcatggtct tttcaactta tccgaccatg attggagcga ttagtggtca agaagaagta
    34081 aatcaacgcc ctttcactgt tgggcatttt gaccttatca taattgacga atctcaccgt
    34141 tctatttatc agaaatacaa gtccattttt gattattttg atgcaagaat tgtaggctta
    34201 acagctactc cgcgtcaaga tttagataaa aacacctatg gattctttaa tttggagaat
    34261 ggggttccaa catatgcata tgatttggaa gaggctgtta aagacggata tttagtagcc
    34321 tatcattcta tcgaaaccaa actgaaacta cctacggatg gtctacatta tgatgatttg
    34381 tccgaagaag aaaaggaaca ttttgatagc aaatttgaag acgatagctg tgaaaaagat
    34441 attgatggga gtgtatttaa ttcctttgtt ttcaataaaa gtacagtaga aattgtttta
    34501 aatgaactca tgacaagagg aattcagaca gcctcgggtg atgaaattgg taaaactatt
    34561 atttttgcta aaaatcatga tcatgcggaa tatatcagag gtatttttaa caaccgctat
    34621 cctgaaaaag ggagcgacta tgctcaggtg attgattata gtattaagca ttatcagacc
    34681 ttgattgatg attttaaaat taaggagaag tatcctcaaa ttgcgatttc tgtcgatatg
    34741 ttagatacag gtattgatgt accagaggtt gttaatttag tcttcttcaa gaaagtacgc
    34801 tctaaaacta agttttggca gatgattggt cgaggaaccc gtctatgtaa agatttattt
    34861 ggacctgagc aggataagga aaacttcttg gtatttgatt atggggacaa ttttgattat
    34921 tttcgtgcag atccaagaga tggagagggt cgtcacattg tttcgttgac tcagcgttta
    34981 tttaatatca aagtggactt gattcgagaa cttcagggac tccaatacca agaagatcag
    35041 tttgcgagag cataccgtca gcagcttgtc tcggaacttc aaggtcgtat agagagctta
    35101 aatgagttgg acttcagggt tcgtatggtt ttagatacag tttatagcta taggaaattg
    35161 gaaagttggc agaatctaac tactgttaca agtgaaacca ttcaaaaaaa tctctctccg
    35221 cttttatttg atgaagataa agaagatgag atggccagga gatttgattt gtggttgctt
    35281 catattcagt tggggcaact gacagctaaa tcttccactg ttcatatttc ccaagtgatg
    35341 aagacggcta gagctctttc tgctattggc aatatcccgc aggtttttga gcaggctgaa
    35401 attatcagga aagtacagga gcctgaattt tggaaagaag ttaacttgtc tgatttggaa
    35461 aaaattcgtc ttgctattcg agatttatta cagtttttgg ataaaacaga ccgtaaaccc
    35521 tactatgtta actttgaaga tcgtatactc tccactgttc acgagaccac agcatttttg
    35581 caggtcaacg atcttcggtc ttacaatgaa aaagttgagc attatttgaa aactcatctg
    35641 gatgaggagt ccatttctaa gctataccat aataaaaagt tgacatctga tgatatgctt
    35701 gcacttgaaa aattgctttg ggaaaaatta ggtagtaaag cagactacca aagtcattat
    35761 gaaaataagg caattccgag attggttcgt gagattattg gcttagatag agagtctgcc
    35821 aatcgtattt tttctaaatt tttgtcggat gagaatctta atgccaggca gatttcattt
    35881 gtaaaattga ttgtagacta cattgtagaa aatggttttt tagagacgaa agtgttaacg
    35941 caagagccgt ttaaatctta tggttctgtt caactactct tccaacacca actaccagta
    36001 cttcgtaata ttgttcaaat cattgaactt atcaataatc gagctggaga agcggcttaa
    36061 attctaaagt gattgccatg ctgagactca tttaaaatta aaaagagtag aaatttatgc
    36121 tatatatgag aagttttatt aggaagaatg tcatcgtttt cctagaatac agtatcagtt
    36181 gttaagtggt tgataaattt caaagtagat acttgtacca cgatgtttgt tgatcgagtt
    36241 attaacaaaa gagctacttt gattttaaag aaatagaaaa caaaaagccg agcaagaatt
    36301 caattgcagg agaaaatgaa ataatactca ataaaaatca aagagcaaac taggaaacta
    36361 gctgcaggct gctcaaaaca ctgttttgag gttgtagata agactgacga agtcagctca
    36421 aaacatggtt ttgaggttgt agatgaaact gacgaagtca gtaaccatac ctacggcaag
    36481 gcgacgttga cgcggattga agagattttc gaagagtata aatcttccta ggataaagca
    36541 aaacgcatag tatcaagggt tttcaacact tgatactatg cgttttctga tgttaaagac
    36601 tttctaccag tttttttaag cataattgtt agttgtagtc atttattatt cttcaaagaa
    36661 aaatggtggg gcgaattttt tcagttcttc aaagcacttt tgagcagtat ctgcatcttc
    36721 acagatgata agacagacat cattaccaca aagggtagcg atagcgtcag ggaagctcaa
    36781 agtatcaatg atagaaccaa aggattgagc cagtccagga agggttttta gtaggacttg
    36841 gtgttgaact gggcgcatcc agacaagggc gtcttccatg tagagttcga gacgtttttc
    36901 ccattttgag atggaaccat tgttaagaac ataataagcg ctatcttctt cgcggacttt
    36961 tgataggttc atatttttga tgtcgcgtga gagggttgcc tgggttactt gaatgtcgtt
    37021 cttagcaaga agggcttgca actcagcctg tgtatgaatc ttgttttttg tgataagagc
    37081 gcgtataagt tggtggcggt gttctgattt attcataata atgtaactcc ttttagcaag
    37141 gtaaggtaag catggactga gcgaggtcga cagtcaagtg gtagtctgta ttgtcacgga
    37201 tggtgatttc aaagtcagta gtatagagga ctaaacggag agtgtctcct tcttttagct
    37261 tgtaaatagt tggctgcagt tcaaattgaa cgtccatcca ttcatctgca gtaatatcct
    37321 ctactaacag taaatcattt ctattttgta aattaaggta accttttgtc acgactcgtt
    37381 gtgcctctgg tctaaatggc aattcacaga gattttccaa catgtgatag cgaccgttgt
    37441 caatggttct agcacttaaa atagctggat aaggttgtag gtatttcttt tgcccaaatt
    37501 ctagcagttg ggcagataag agccccttgt ttgtactgga tttgatacga agattgagct
    37561 gagcgcgacc gtttaggtgg agatctttag tcacaggaag gttaatagta atctgattag
    37621 ctttcccttg atagagctct gtattgaagg tttggtatgt cttaccatag cgctcaaaat
    37681 ccttatctgg gtactggttt tgaatagctt gctcttcttg accaagtgag aaggtttcac
    37741 agttttcttg cccaccgaag ttatcaagtg ataaccaagt ctgtggagct gtattgtcct
    37801 gccagataac agtaggaagt tgaaagtctg tttcctgtcc tagtaatttc ttggtcaata
    37861 aggcatttat ggactcacgg aagtcaattg attgccaatt gttcatgtaa acatgagcac
    37921 cattatggaa aaagagatgc ttgtgtatat gagtaggaag agcatggaac atctggtaaa
    37981 catgaagtgg tttgacattc caatcctgag aaccatgagt aaagacaacc tctgccttta
    38041 ctttatgggc attgagcaga taattgcggt catgccaaaa ctgattgtag tccccagttt
    38101 ttcggtctag ctgagctttc actttttcta agtcagcttg gtgagcttca ttgccacgga
    38161 tatagtcgcc agctaagaga ttacgagaat aggttaactc agcaagggag tcaaagtcct
    38221 cacctggata accacctggg ctagtcacca gaccgttttc acggtagtag ttgtaccatg
    38281 atgaaattcc tgcctcggca atgataactt ctaaaccatc gactcctgta gtcgcaagac
    38341 cattggacat ggtacctaga taggaaagtc ctgttgtagc aacttttccg tttgaccaat
    38401 cagccttgac ttgacgctgg cgcgtgtgat cagtaaaggc acggcaacgg ccgttaagcc
    38461 aatcgatgac atttttataa gcctcgattt gctggtagtc tccattagtc atgaaacctg
    38521 tcgagtcttt ggtaccaaca cctgagacat agagattggc aaagcctctc ggaaggaagt
    38581 agtcgtttag tgtatagcta gagttgatgt gagttagctt ttcctcagcc tctgctataa
    38641 gctcagcttt accttggggt tggacgagat ttagttgagg tttctctagc tcaatcttgt
    38701 gaggaagctt aacctcaagc tcgccctcca tcttgtagag agccttgtca ctagccttgt
    38761 cattggttcc ctgatgataa gggctggctg tcatgatggc agggattttt ccatcaaaac
    38821 gagggcgaat aatgctaacc tttactaggt ctgatagccc tttttggtca gtatcgacac
    38881 gagactcaac gtaaacgact tcacgaatga catcctggtt agaaaaagta gccaaactct
    38941 tgccgttaaa gtagtggtag tcattatcct ccggaataag accatcacta acaagttggt
    39001 cgataagagt atttcctttt ttggtgcgag tattgagtaa ctgatagaga ttttcaatca
    39061 agtcaccata tataatggga aatccagttt ctttacgaaa aacgtcacta tcttcgaagt
    39121 caaccaaata agaaaagcct aaaagttgaa aagcaacagt ataaaaaata tctgctgtca
    39181 gttcatcttc tgattgaaaa aatgtcagca ggtctgtttt tttatcagct gctaggatag
    39241 aaagtgggta gttggtgtct tgataagtga aaaagaaacg acgtaaaaag gtttcaagtg
    39301 agtctttgtg attggctgta ttttgtaaat caaagccaca tttttttagt tcagataaga
    39361 cattttcttt tggaaaattg atataactat attgattaaa acgcatagaa cctccatata
    39421 gaatgacagt taaggttatt atatcaaaaa aaaagcagaa agggaattgt taacttcaaa
    39481 aggaaataat ccaataaaaa tgaataaagt actaaattca atatagagaa cagagtaaca
    39541 ataagaataa atagataggg tataaaagtt ctaggagatt tatattatat gctttctatt
    39601 tttatataca atatagtata aatataaaaa tgatgacaaa aatacaaatg aatagaaaat
    39661 aaattagtaa gctgatgaaa tttttctcaa gagaagccat ttataggtga aaatggtata
    39721 atatagtgag aaggatagag gagaagtgta aattgatcgc acaactagat acaaaaacag
    39781 tctatagttt tatggaaagc gtcatttcga tcgaaaagta tgtgagagca gctaaagaat
    39841 acggctacac tcatttggct atgatggata ttgacaatct ttatggcgct ttcgactttc
    39901 tagagattac aaaaaaatac ggcattcatc ctttgctagg gcttgaaatg acagtgtttg
    39961 tagatgatca ggaagtgaat ttgcgctttt tagctctatc tagtgtgggc tatcagcagt
    40021 tgatgaagct ttcgacagcc aagatgcagg gggagaaaac ttggtcagtc ctgtcccagt
    40081 acctggagga tatcgcggtc attgtgcctt attttgatag agttgagtcg ttagaactag
    40141 gctgtgatta ctatataggg gtttatccag aaacactagc aagcgaattt catcatccta
    40201 tcttacctct ttatcgggtc aacgcttttg aaagcaggga tagagaagtt cttcaagttt
    40261 taacagcgat taaagaaaat ctaccgctca gagaagttcc cttgcgttcg agacaagatg
    40321 tctttatatc agcaagttct ttagagaaac tattccaaga gcgttttccg caagctttgg
    40381 acaatttaga aaagcttatt tcaggcattt cttacgactt ggatattagt ctgaaactgc
    40441 ctcgttttaa tccagctaga ccagcagtag aggagttgag agagcgtgct gaactggggt
    40501 ttgttcagaa ggggttgact agtaaagaat atcaagatag actagaccaa gaattgtctg
    40561 ttattcatga tatgggcttt gatgattatt tcttggttgt ttgggatttg ttgcgttttg
    40621 gacgatcgaa tggctattat atgggaatgg gaaggggttc tgcagtaggc agtttggttt
    40681 cttatgcctt agacatcacg gggattgacc cagtaaagaa aaatctgatt tttgaacgct
    40741 ttcttaatcg tgaacgctat accatgcctg atattgatat tgatatccca gatatttatc
    40801 gtccagattt tatcagatat gttggtaata aatatggtag taaacatgcg gcacaaatcg
    40861 ttactttttc aacctttgga gccaagcaag ctcttcgaga tgtcttgaaa cgctttggtg
    40921 tgccagagta tgaattatct gcaattacta agaaaatcag ttttcgtgac aatcttaagt
    40981 cggcctatga gggcaatctc cagtttcgtc agcaaatcaa tagtaagtta gaataccaaa
    41041 aagcttttga gattgcttgc aagatagagg gctatccaag gcaaacctct gtccatgcgg
    41101 ctggtgttgt aattagtgac caagatttaa ccaactacat tcctctaaag tatggtgatg
    41161 aaattccact gactcagtat gatgctcatg gagttgaggc tagcggactt ttgaagatgg
    41221 actttctggg actacgaaat ttgacctttg tccagaagat gcaagagttg cttgctgaaa
    41281 cagaaggtat tcaccttaaa attgaagaaa tagatttgga agacaaagaa acgttagatt
    41341 tatttgcctc tggaaataca aaaggtatct ttcaatttga gcaacctggt gccattcgct
    41401 tgctcaaacg tgttcaacca gtctgttttg aagatgtcgt agcaactact tctctaaatc
    41461 gaccaggtgc aagtgactac atcaataatt ttgtggcaag gaagcatggg caggaagaag
    41521 tgactgttct agattcagct ctggaggata ttttggctcc aacttatggc attatgctct
    41581 atcaggagca ggttatgcag gttgctcagc gatttgctgg atttagtctt gggaaggccg
    41641 atattttgcg tcgagctatg ggtaaaaagg atgcctctgc tatgcatgag atgagggctt
    41701 cctttattca aggctccata gaagcaggcc atactgcgga aaaagcagag caggtttttg
    41761 atgttatgga gaagtttgca ggttatggat ttaatagatc tcatgcctac gcctactcag
    41821 ccttggcctt ccagttggct tatttcaaaa cgcattatcc agccattttt tatcaggtca
    41881 tgttaaatta ttccaacagt gattacttaa tagatgcact tgaagcaggt tttgaagtag
    41941 cctctctatc catcaatact attccctatc acgataaaat tgccaacaag tctatctata
    42001 taggtttgaa atcgattaag gggctcagca aggacttggc gctttggatt attgaacata
    42061 gaccttattc taacattgaa gattttatag ctaaattacc tgagaattat ctgaaacttc
    42121 ctctgctaga acctttggta aaagttggtc ttttcgattc atttgaaaaa aatcgtcaaa
    42181 aagtatttaa taacttagct aatctatttg aatttgtgaa agagttggga agtttgtttg
    42241 gagatgctat ttatagttgg caggaatcgg aagattggac ggaacaagaa aaattttata
    42301 tggaacaaga gcttttaggg ataggtgtca gcaaacatcc actacaagct attgcaagta
    42361 aggctattta cccgattacc ccaatcggaa atttgtcaga aaatagctat gctattattt
    42421 tggttgaagt tcagaaaata aaagtgattc gtaccaaaaa gggtgaaaat atggccttct
    42481 tacaggcaga tgatagtaag aaaaaattgg atgtcactct cttttcagac ttatatcgtc
    42541 aggttggaca ggaaataaaa gagggagcct tctactatgt aaaaggaaaa atacaatcac
    42601 gtgatggccg tctgcaaatg attgcacaag aaataagaga agcagttgct gaacgctttt
    42661 ggatacaggt gaaaaatcat gaatcggatc aagaaatttc acgcatttta gaacaattta
    42721 aaggcccaat cccagtcatc atccggtatg aagaggaaca gaaaaccatc gtttctcccc
    42781 atcattttgt agctaaatcc aatgaattag aggagaaatt gaatgaaatc gttatgaaaa
    42841 cgatttatcg ctaaaaatac ggaaaataga agaattttaa aatcaaatgt gatataatca
    42901 agaagaatgt taaaagaaaa aggagcataa accaatatga aacgtattgc tgttttgact
    42961 agtggcggag acgcacctgg tatgaacgct gccatccgtg cagttgttcg tcaagcaatt
    43021 tcagaaggaa tggaagtgtt tggtatctat gacggatatg ctggtatggt tgccggtgaa
    43081 attcatcccc tagatgcagc ttcagtaggg ggcatcattt ctcgtggtgg tacttttctt
    43141 cactcagctc gttatccaga gttcgctcaa cttgaagggc aacttaaagg gattgagcaa
    43201 ttgaaaaaac acggaattga aggtgtagtt gttatcggtg gtgacggatc ttaccacggc
    43261 gctatgcgtt tgactgaaca tggcttccca gctattggtc ttccaggtac aatcgataac
    43321 gatatcgttg gtactgactt tacaatcggt tttgacacag cggttactac tgccatggac
    43381 gctatcgata agattcgtga tacatcatca agtcaccgtc gtacttttgt aatcgaagtt
    43441 atgggacgta acgctggtga tatcgctctt tgggctggta ttgcaactgg tgctgatgaa
    43501 atcatcatcc ctgaagcagg cttcaagatg gaagatatcg tagcaagcat caaagctggt
    43561 tatgaatgtg gtaaaaaaca caatatcatc gtcttagctg aaggtgtgat gtcagcggct
    43621 gaatttggtc aaaaacttaa agaagctgga gatacaagcg accttcgtgt aacagaactt
    43681 ggacatattc aacgtggtgg ttctccaact gcgcgtgacc gtgttttggc gtcacgtatg
    43741 ggtgcacatg ctgttaaact tcttaaagaa ggtatcggtg gtgttgcggt tggtattcgt
    43801 aacgaaaaaa tggttgaaaa tccaattctt ggtactgcag aagaaggggc attgtttagc
    43861 cttactgcag aaggtaagat tgtggttaac aacccgcaca aagccgatat tgagctatct
    43921 agcttgaata agagcttgtc ataatttaca atttagttaa taagaccaaa aaggtcatat
    43981 atataaagga gtcacaaaaa tcatgaacaa acgtgtaaag atcgttgcaa ctttgggtcc
    44041 tgcggtagaa atccgtggtg gtaaaaaatt cggtgaggat ggatactggg gtgaaaaact
    44101 tgatgttgaa gcttcagcta aaaacattgc taaattgatt gaagctggtg ctaacacatt
    44161 ccgattcaac ttctcacacg gcgaccacca agaacaaggt gagcgtatgg caactgttaa
    44221 acttgcggaa aaaattgcag gtaaaaaagt tggtttcctt cttgatacaa aaggacctga
    44281 aatccgtaca gaattgttcg aaggtgaagc taaagaatat tcatataaaa ctggtgaaaa
    44341 aattcgtgtt gcaactaaac aaggaatcaa atcaactcgt gaagtgattg cgttgaacgt
    44401 tgctggtgct cttgatatct atgatgatgt tgaagttggt cgtcaagttt tggttgacga
    44461 tggtaaactt ggtcttcgtg tggttgctaa agatgatgca actcgtgaat ttgaagttga
    44521 agttgaaaac gatggtatca tcgctaaaca aaaaggtgtg aacatcccta acactaaaat
    44581 tcctttccca gctcttgctg aacgcgataa cgacgatatc cgtttcggtc ttgaacaagg
    44641 tatcaacttc atcgcaattt cattcgtacg tactgcaaaa gatgtgaacg aagttcgtgc
    44701 aatctgtgaa gaaactggaa acggacatgt tcaattgttc gctaaaatcg aaaaccaaca
    44761 aggtatcgat aacttagacg aaattatcga agcagctgat ggtattatga ttgctcgtgg
    44821 tgatatgggt atcgaagtac cgttcgaaat ggttccagtt tatcaaaaaa tgattatcaa
    44881 gaaagtcaat gctgcaggta aagttgttat cactgcaaca aacatgcttg aaacaatgac
    44941 tgaaaaacca cgtgcaactc gttcagaagt atcagacgta ttcaacgctg ttatcgacgg
    45001 aactgacgct acaatgctgt caggcgagtc tgcaaacggt aaatacccac tcgagtcagt
    45061 aactacaatg gctacaatcg acaagaacgc tcaagctctt cttaatgaat acggacgtct
    45121 tgattcagat tcatttgagc gtaactctaa gacagaagta atggcttctg ctgttaaaga
    45181 tgctactagc tcaatggata tcaaattggt tgtaactctt actaagacag gtcatactgc
    45241 acgtttgatt tctaaatacc gtccaaatgc tgacatctta gcattgacat ttgacgaatt
    45301 gacagaacgt ggcttgatgt tgaactgggg tgttatccca atgttgacag atgctccatc
    45361 ttcaactgac gatatgttcg aaatcgctga acgtaaagcg gtagaagcag gtctcgttga
    45421 gtcaggcgat gatatcgtta tcgttgctgg tgtgccagta ggagaagctg ttcgcacaaa
    45481 cacaatgcgt atccgcacag tacgttaaga aaaatataaa aacctatcat atctagcttt
    45541 ctagcctgta tgatgggctc tttttttgtc cagggggcaa aactttcata atggatt
//
LOCUS       DBERPV010000014        43425 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.14, whole genome shotgun sequence.
ACCESSION   DBERPV010000014 DBERPV010000000
VERSION     DBERPV010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 43425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43425
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.14"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..658)
                     /locus_tag="ACL8C7_001010"
     CDS             complement(<1..658)
                     /locus_tag="ACL8C7_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HGS1395232.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     Q"
     gene            1255..1839
                     /locus_tag="ACL8C7_001011"
                     /pseudo
     CDS             1255..1839
                     /locus_tag="ACL8C7_001011"
                     /inference="COORDINATES: protein motif:HMM:NF021048.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
     gene            1836..3014
                     /locus_tag="ACL8C7_001012"
     CDS             1836..3014
                     /locus_tag="ACL8C7_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000217311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HGS1395233.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGVDM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     "
     gene            3183..3809
                     /locus_tag="ACL8C7_001013"
                     /pseudo
     CDS             3183..3809
                     /locus_tag="ACL8C7_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_050084071.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
     gene            complement(4264..5628)
                     /locus_tag="ACL8C7_001014"
     CDS             complement(4264..5628)
                     /locus_tag="ACL8C7_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1395234.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRVAI
                     ASVMCKNSPFVFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
     gene            complement(5616..6311)
                     /locus_tag="ACL8C7_001015"
     CDS             complement(5616..6311)
                     /locus_tag="ACL8C7_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGS1395235.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGINF
                     KNPVKYLEYVSVPLLIISSNISDDIAKAAEIKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VVGLIVGGLIWLK"
     gene            complement(6311..6895)
                     /locus_tag="ACL8C7_001016"
     CDS             complement(6311..6895)
                     /locus_tag="ACL8C7_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HGS1395236.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            complement(6906..8627)
                     /locus_tag="ACL8C7_001017"
     CDS             complement(6906..8627)
                     /locus_tag="ACL8C7_001017"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1395237.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDEGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENTDKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            complement(8611..10365)
                     /locus_tag="ACL8C7_001018"
     CDS             complement(8611..10365)
                     /locus_tag="ACL8C7_001018"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1395238.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISALLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAINDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            10525..11517
                     /locus_tag="ACL8C7_001019"
     CDS             10525..11517
                     /locus_tag="ACL8C7_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS1395239.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            complement(12137..13699)
                     /gene="guaA"
                     /locus_tag="ACL8C7_001020"
     CDS             complement(12137..13699)
                     /gene="guaA"
                     /locus_tag="ACL8C7_001020"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HGS1395240.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAVEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            13841..14539
                     /locus_tag="ACL8C7_001021"
     CDS             13841..14539
                     /locus_tag="ACL8C7_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGS1395241.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(14582..15478)
                     /locus_tag="ACL8C7_001022"
     CDS             complement(14582..15478)
                     /locus_tag="ACL8C7_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGS1395242.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGTLMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLIIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAVFFAFLIMNEQFYTIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(15487..16422)
                     /locus_tag="ACL8C7_001023"
     CDS             complement(15487..16422)
                     /locus_tag="ACL8C7_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HGS1395243.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(16419..17144)
                     /locus_tag="ACL8C7_001024"
     CDS             complement(16419..17144)
                     /locus_tag="ACL8C7_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HGS1395244.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQIDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(17228..17863)
                     /locus_tag="ACL8C7_001025"
     CDS             complement(17228..17863)
                     /locus_tag="ACL8C7_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HGS1395245.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKFLKDYLY"
     gene            complement(17865..18692)
                     /locus_tag="ACL8C7_001026"
     CDS             complement(17865..18692)
                     /locus_tag="ACL8C7_001026"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGS1395246.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALTHFKVRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(18714..19049)
                     /locus_tag="ACL8C7_001027"
                     /pseudo
     CDS             complement(18714..19049)
                     /locus_tag="ACL8C7_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
     gene            complement(19050..19766)
                     /locus_tag="ACL8C7_001028"
     CDS             complement(19050..19766)
                     /locus_tag="ACL8C7_001028"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF021127.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HGS1395247.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPVEVMDAIKEAGYHVLDLAHNHILDSQIEGVISMADII
                     EKAGITPIRVYTHEPRDQAPLVIKEVNAIKVALLAYSYGFNGIEQYIFQEDYNRYLSD
                     LNEDKIKAEVERAEKEADITIIMPQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSETVEKDGDKKLIIY"
     gene            complement(19846..20037)
                     /locus_tag="ACL8C7_001029"
     CDS             complement(19846..20037)
                     /locus_tag="ACL8C7_001029"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395248.1"
                     /translation="MKIQRRQNRNQGGLAFRFMKGLVNFLGVIASGAIRDLWRYSCSQ
                     LVYQWAWSCCLKASKESLD"
     gene            20289..20900
                     /gene="def"
                     /locus_tag="ACL8C7_001030"
     CDS             20289..20900
                     /gene="def"
                     /locus_tag="ACL8C7_001030"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGS1395249.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEGIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            20945..21673
                     /gene="rlmB"
                     /locus_tag="ACL8C7_001031"
     CDS             20945..21673
                     /gene="rlmB"
                     /locus_tag="ACL8C7_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HGS1395250.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKNLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENSLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(21712..22623)
                     /gene="trxB"
                     /locus_tag="ACL8C7_001032"
     CDS             complement(21712..22623)
                     /gene="trxB"
                     /locus_tag="ACL8C7_001032"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HGS1395251.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVRKIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(22689..22913)
                     /locus_tag="ACL8C7_001033"
     CDS             complement(22689..22913)
                     /locus_tag="ACL8C7_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HGS1395252.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(22991..23734)
                     /locus_tag="ACL8C7_001034"
     CDS             complement(22991..23734)
                     /locus_tag="ACL8C7_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS1395253.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(23734..24534)
                     /locus_tag="ACL8C7_001035"
     CDS             complement(23734..24534)
                     /locus_tag="ACL8C7_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS1395254.1"
                     /translation="MNVTTILASDWYQNLMQLIPNGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(24692..25048)
                     /locus_tag="ACL8C7_001036"
     CDS             complement(24692..25048)
                     /locus_tag="ACL8C7_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HGS1395255.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(25042..25572)
                     /locus_tag="ACL8C7_001037"
     CDS             complement(25042..25572)
                     /locus_tag="ACL8C7_001037"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HGS1395256.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRSNRRRSTC"
     gene            complement(25572..26066)
                     /locus_tag="ACL8C7_001038"
     CDS             complement(25572..26066)
                     /locus_tag="ACL8C7_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HGS1395257.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            26201..26647
                     /locus_tag="ACL8C7_001039"
     CDS             26201..26647
                     /locus_tag="ACL8C7_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HGS1395258.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            26644..27291
                     /locus_tag="ACL8C7_001040"
     CDS             26644..27291
                     /locus_tag="ACL8C7_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HGS1395259.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWILMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASVLQYIAIVYYM"
     gene            complement(27312..27893)
                     /gene="pdxT"
                     /locus_tag="ACL8C7_001041"
     CDS             complement(27312..27893)
                     /gene="pdxT"
                     /locus_tag="ACL8C7_001041"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HGS1395260.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(27894..28769)
                     /gene="pdxS"
                     /locus_tag="ACL8C7_001042"
     CDS             complement(27894..28769)
                     /gene="pdxS"
                     /locus_tag="ACL8C7_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042819 - vitamin B6 biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HGS1395261.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(28921..30300)
                     /gene="nox"
                     /locus_tag="ACL8C7_001043"
     CDS             complement(28921..30300)
                     /gene="nox"
                     /locus_tag="ACL8C7_001043"
                     /EC_number="1.6.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="H2O-forming NADH oxidase"
                     /protein_id="HGS1395262.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFGRLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            30594..31517
                     /locus_tag="ACL8C7_001044"
     CDS             30594..31517
                     /locus_tag="ACL8C7_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HGS1395263.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGISPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            31577..32182
                     /locus_tag="ACL8C7_001045"
     CDS             31577..32182
                     /locus_tag="ACL8C7_001045"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HGS1395264.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEEFDWENL"
     gene            32200..33447
                     /locus_tag="ACL8C7_001046"
     CDS             32200..33447
                     /locus_tag="ACL8C7_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HGS1395265.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRNFKFKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAGGHGHGDADATS
                     GASDAGDAGGHGGGADATAGASY"
     gene            complement(33564..33821)
                     /locus_tag="ACL8C7_001047"
     CDS             complement(33564..33821)
                     /locus_tag="ACL8C7_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HGS1395266.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(33863..35899)
                     /gene="glyS"
                     /locus_tag="ACL8C7_001048"
     CDS             complement(33863..35899)
                     /gene="glyS"
                     /locus_tag="ACL8C7_001048"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HGS1395267.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQSVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(36111..37028)
                     /gene="glyQ"
                     /locus_tag="ACL8C7_001049"
     CDS             complement(36111..37028)
                     /gene="glyQ"
                     /locus_tag="ACL8C7_001049"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HGS1395268.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            complement(37047..37808)
                     /locus_tag="ACL8C7_001050"
     CDS             complement(37047..37808)
                     /locus_tag="ACL8C7_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HGS1395269.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(38081..38923)
                     /locus_tag="ACL8C7_001051"
     CDS             complement(38081..38923)
                     /locus_tag="ACL8C7_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HGS1395270.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYHAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQEEVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     VAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(39037..40428)
                     /gene="pgdA"
                     /locus_tag="ACL8C7_001052"
     CDS             complement(39037..40428)
                     /gene="pgdA"
                     /locus_tag="ACL8C7_001052"
                     /EC_number="3.5.1.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050119 - N-acetylglucosamine deacetylase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-N-acetylglucosamine deacetylase
                     PgdA"
                     /protein_id="HGS1395271.1"
                     /translation="MDKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(40666..41034)
                     /locus_tag="ACL8C7_001053"
                     /pseudo
     CDS             complement(40666..41034)
                     /locus_tag="ACL8C7_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603324.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
     gene            41273..42250
                     /locus_tag="ACL8C7_001054"
     CDS             41273..42250
                     /locus_tag="ACL8C7_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGS1395272.1"
                     /translation="MLKLGIIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLTG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            42247..43329
                     /locus_tag="ACL8C7_001055"
     CDS             42247..43329
                     /locus_tag="ACL8C7_001055"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGS1395273.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLTSDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
BASE COUNT        13432 a         9108 c         7402 g        13483 t
ORIGIN      
        1 cctgcaaact cttacgttct ttcccaaatg gcatatcgta aaggtcgtat ttccaacggc
       61 atgactgaga acatccacca cggttggcat cacgcatact catgtggttt gaaagagtac
      121 aacgtccaga gtatgaaata cacatagctc catggacaaa ggcttcaatt tcaacatctg
      181 tacgtttgcg gatctcagct aattcttcca ttgaaacctc acgcgctaaa acgacacgag
      241 tcaagcctag ctctttccag aactcaaggg tttcatagtt agtggcactg gcttgggtag
      301 aaaggtggat ttcaaggcct ggtgcttcag tcgctgcaat cataatcaag gctgggtcag
      361 atacgataac tgctgcaatc ccgatatcac gcagtttacg gaaccactca ccagcaccag
      421 cttcatttcc ttcgtgcata accatattag ccgctacata gaccttggca ccatacttgg
      481 ccgcaaactg cacgccttct tccatctgtt cgaaagtaaa gtttcccgca cggctacgaa
      541 gaccataggc ctgaccaccg ataaagacag catctgctcc atactgaaca gctaccttta
      601 gcttctctaa agtccctgca ggtgataaaa cctcaggacg ttttaatgtt tttgtcatga
      661 tttctcctat ttgcaatata aaagtttgac atttttcctt ctcattttat agtaaataaa
      721 ggataaaatc aagcctagac ggattgtttt gacaattcta atcttttaga ctttgcataa
      781 taactgttaa acagtcgaaa attaccccag ttttaacaag tagtcaaaaa gtctaaaaaa
      841 gtaaaaacca gtatcccaag atactgactc gtaaaaatac ataaattagt ccttagatga
      901 ctactcccac tctgttgctc ctataatgga aaaggattga tacagtctag aatatcgctt
      961 ttttatttat tattctgata taaaactgtt agaattgatt ttttgtttta tacccaaata
     1021 tgaatagaga cgtagctaat aagttgaata acatatttgg aaaaatgaga aatagcaata
     1081 ttactagaac ttttagaaac aatcaatatt taaaaagaaa aaagctcaaa gaatttatta
     1141 aaccatgtta taatagatat agctataatt ttatttataa caagaggata gaaatgaccg
     1201 aattagaaag aaaaaatcga aaaattagct aagaaatatt ctgataactt aaacatcaaa
     1261 gttcaagaga gagttcgtga aatggcaaat gataataaga gccattattt gatatacaga
     1321 gttttaggta tttcatttga agaaggagaa aatatcgatt tgtatcaaaa taaaggtcgt
     1381 tttttataca aatatgctgg ttaattttta gaagaagctg cagtactatg ctttaacgaa
     1441 aaatttggta cagaaaatac ttaaaaagtt aacattccta attctgaaag tacaaaacct
     1501 aagacttttg aaattgattg tttagtcgga gaaaaacacg catacgaaat aaaatggtgg
     1561 gatgcaacta cagatggaga ccatataact aaagaacaca ctagaataaa agttattcat
     1621 aacaaaggat atataccaat tcggttaatg ttctactatc caaatagaac tcaagctata
     1681 aaaattcagc aaactttaga aacattgtat aacggtattg gagggaaata ttattatgga
     1741 gattctgcct gggaacattt aagagcagtg accggtattg atttacttag tattctaaca
     1801 gatattgcaa ataaaaaaac aggggtaaaa tcaaaatgac agtattaaaa ggagataact
     1861 tagaaatatt aaaaactatt gaatcctcaa gtattgattt aatctatatg gaccctcctt
     1921 tctttacaca gaaaacccaa aaattatcta ataacaaaaa tattatgtat tcattcgaag
     1981 atacgtggac ttcgattgag gattacaaag aatttttgtc tgtaagatta gaagaatgca
     2041 aaagagtgct aaaaaatagt ggcagtattt tcgttcattg tgataaaatt gcaaatcatc
     2101 atattagatt aattttagat aatatctttg gagtagatat gtttcaaagc gaaattatat
     2161 ggaactataa acggtggtct aattcaaaaa agggattatt gaacaatcat caaaacattt
     2221 acttttattc aaagtcaaaa gattttaaat ttaatacaat ttttacagag tattcttcta
     2281 ctacaaatat cgaccaaata ctagtggaac gaaaacgaga tggaaactct aaaactatat
     2341 ataaagttga taataatggt aactatattc tagcaaaaga gaaaaatgga gttccccttt
     2401 cagatgtttg gaatatacca tttcttaatc caaaagctaa agaaagagta ggttatccta
     2461 cacaaaaacc tattctgtta ttagaacaaa ttataaagat tgctactgat aaaaatgata
     2521 tagttttaga cccgttctgt ggaagtggaa ctactttagt agcctccaag attttgaata
     2581 gaaattatat ggggattgat ttatctgagg aagctatcaa tataactcag caacgtctgg
     2641 aaaatgttat aaaaacaagt tcaaatttat tgaataaagg aatcgaagca tatagaacca
     2701 aaactgagga agaggaaaac attcttaaat tattacaggc aaaaattgtt caaagaaata
     2761 aaggaattga tggtttttta cctaaacatt ttcaaaaaaa accgatacct ataaaaattc
     2821 aaaaaaataa tgaatgtctg aatgagagta tctctttatt acagaatgct ataaactcca
     2881 aaaaacttga ttttggagta gttataaaaa ctcattcaga taatttatta tttgattttg
     2941 atacgattcc tgaaaatata atagtagttg accattttga acttacaatc gaaaaatggt
     3001 taagtaaaag ttaacagtta ctatagtttg caaattattt acagaaagaa caagaattcc
     3061 taggagatta ttctggctat gttcattgtg acatgttgcg gcagtaactt aggactttag
     3121 tcctctagtt ctgcctatgc gatagcagtc caaagtttag gagtaaggcg acgctaagct
     3181 tggtaaactg cgaacagcta gaagcttatc gtcaactgga agaagctgca cttgttggat
     3241 gttgggcgca tgtgagaagg aagttttttg aagcgacccc caagcaagca gataaatcat
     3301 ccttaggaac taaaggttta gcttattgtg atcagttatt ttccttggaa agagactggg
     3361 aggctttgcc agctgatgaa cgactacaga aacgtcaaga acatctccaa cccctactgg
     3421 aagacttctt tgcttggtgc cgtcgtcagt cagttttatc gggttcaaaa ctaggaaggg
     3481 caattgaata cagcctcaag tatgaagaaa cctttaagac cattttaaaa gacggacatc
     3541 tggtcctttc caataatcta gctgaacgcg ccattaaatc attggttatg ggacgtaaaa
     3601 attggttgtt ttctcaaagt tttgaaggag ctaaagcaag agctattatt atgagcttat
     3661 tggaaacagc taaacgtcat caactaaata gtgagaaata tctatcctat cttctagaat
     3721 gtcttccaaa cgaggaaact ctcgtaaaca aagaggtttt agaggcctat ttaccgtgga
     3781 ctaaagttgt acaagaaaag tgcaaataag aaatctccag attaggaact atatatgagt
     3841 tctctagtct ggagattttt caatatactt cgttattggg cggttacaat ttattatatg
     3901 aaaatcccat atcattctcc aattctatat tttacctttc taaatgtata gattaactac
     3961 ctaattatat catataacgc agattccttt caatcgtatg atttactgca ttaaattaag
     4021 taaaaaaata aaggcagtcc gaagactgcc gatatttatc tctcatctct ttaattatgg
     4081 taagtaaata aataatttcc ctaaagatat ggaaattatt aatactataa atacatatta
     4141 taaagtttat aaatactgta aaaatcctga agttaatttt ctaataaata tcaatatgtg
     4201 ttagtatctt ttaaattttt agacaattta ccagttctat agacatgttt aacagactct
     4261 attttacaat tcaaaaattt catctgccac ttcatttaaa aattctatat catgggaaac
     4321 aataaaaatt attttatcca tggttttata cttattaatc agttcagata tttttatcat
     4381 attggaataa tccataccac ttgaaggttc gtcaaaaaag acaaatggag aattcttgca
     4441 cataacagat gctattgcaa ccctttgctt ttgccctcct gataaactca tcggatgcct
     4501 ttcaataaat tcgtccaggc ctaaatcttt taaaatgatt ttcgcctttt cttcatcaaa
     4561 attctttact cctaatctaa gctcgttgaa tacttcatct gtgaataatt gatgatttac
     4621 atcttgcata acaagtgaag agtttttgag tctttctttt ttagatagct tctctccctt
     4681 aaaataaatt tcttcttttg attttttctc aagacctatt aaacatctta aaagcgttga
     4741 ttttcctcgt ccgttggatc ctattatgcc ataaattttc ccaagcttga acgaaatatc
     4801 ttttaagctt aaacactcat catcagtaaa tttgtagcta agatttttta tctgatactc
     4861 tccaccttct tttaaataag gaacttttaa tttacttaat tctttatctc ttaaacttaa
     4921 agcatttaat tcatttttat ctagctttaa aaattcactt ctagtataag tttttttaag
     4981 ctttccttta tctattaaaa atacacggtc aactatgtcc atcaaataat aaattctatg
     5041 ctctgcaaca attatgctta tgcctttctc ttttaatatc tttagcatct ttgccaaaac
     5101 acttatgctt ttaatatcta aattcgatga aggctcatcc ataactataa tctttgtacc
     5161 tgctatataa gaagctgcaa tgcaaagaat ttgtttttca ccgccggata gattaaatat
     5221 atttctgttc aaaagatttt ttatcgggaa tatctcaagc atatccttca aacgcctgtc
     5281 catctcttct cttgcaagac cgatattttc caaataaaat aataattcta atgtcgtatt
     5341 gacattaaaa aaatatgtct taggattttg aaaaacagtt gaaacaagca ttgagatttg
     5401 ataaagttcc aaatttttta tattcttacc atcaataatt atttcgccct ttgtctttgc
     5461 gttatcatac cttacagcta gtccattgat tgaatttatt aaagatgact taccatttcc
     5521 actttttcct gtaaatagca cgcactctcc ctcggctatg gatagtgata tatcatctaa
     5581 tatatgctct tcaccataat caagacttaa attttttatt tcaaccatat taagcctccc
     5641 acaataagtc caacaaccgc taaaacataa acaaaatcaa ttagctgtat ctttacgcga
     5701 atgtatctgg tcttggcaat tggattttct attgccttta tttctgccgc ttttgcaatg
     5761 tcatctgata tattagatga tataatgagt agtggcacag aaacatattc aagatatttg
     5821 actgggtttt taaaatttat ccctcttact ctcatagcca ttttgatgtt tttcttctcc
     5881 tccttaaaag atgggaagaa tctaaacata accgcaatag gtatggatac attctttgaa
     5941 atcttaagct tatccatcga tgaaattatt gcgcctacat ccgaggtctt tatcataaag
     6001 cttgctgcca taaatggtaa aataaacatt ctaataacaa taggtatact caaaaacatc
     6061 ttaactatag ggtttaattc agataacacc ataaaattag gcaaggagta aagtatccca
     6121 cacaatataa tccatttgaa aagtgttttt ttgtatccat tcaaataaag caaaatacca
     6181 ataagacaaa caattgccag ctcaaaacgg atgtttatgc tatgcataac agttaagcct
     6241 gtgataaata cgactaatat cttagagatc ggattgggat taaagggagc atttgaagaa
     6301 aaagtaggca ttatacaatg cctgcttttt caaagtgttt tttcaataga gccttgccta
     6361 tatatgctcc aagaattcct cctaagaaag cacctaaggc tactaaagcc atgtgaggat
     6421 aagttattaa cttttctaat acatcaacat aatcttttcc catcgtcatc aaagaccact
     6481 ccatatattt ttcttttgct aaaagcattt gcattaaaga gctacatatc catgtgctga
     6541 agattgcata agaaagcata ttgtatttaa atgaattata attaccaatc tttctaatta
     6601 attctgctat tatcattact ataagtgata aaaccacaac tacgtaggta tgaccagctg
     6661 caaacatcac aagtggtgat atcataccaa atataaatag tgcccatggc ttttgaacct
     6721 tagccataaa taacataaca acagttcctg caactatggc taatactgtc gggtatatta
     6781 agaacaatat tggaatcaag cccatcatac caactccaaa catgaaggca aaataaatta
     6841 cgccaaaaac accgatgctt actaaatctt ttacttttaa ttttttatta tccattgtag
     6901 tcctcctaat aaataaattc ttctgccatt tttgtctttt ctattaaatt tttgtaaatt
     6961 tttgattttt gtaaaagctc ttcatgctta ccttcgcttt ctactcttcc gttttgaaga
     7021 actactatct tgtctgtatt ttctatggat ttcattctat gtgaaatgat tacaacagtt
     7081 ttatctttaa ctaaattatt taaagactct tgaatctttt tctcgttgtt aacatcaagg
     7141 cttgctgtta tctcatctaa gatcaatatc ggcgcatctt ttaagaaggc tctggctatt
     7201 gataatcttt gtctttctcc tcctgatagc tcagctccgt tctcaccaat aactgtatcg
     7261 aaacctttat ccattttttc tataaaatct gtgcaatttg caagttttgc tgctctttta
     7321 acctcttcgt cacttgcatc ttgctttccg attctaatat tttccataac gctttgatta
     7381 aagagaacca catcttggaa aactatagag accttatcaa aaagagattc tgttgatatt
     7441 tcttttatat ctttgccatc gattaagatt tgtccctcgt cataatcata aagtcttgat
     7501 ataagtttca agatagttgt tttaccgcag ccacttgcac ctaccaaagc agtgacctct
     7561 ccctgcttag ctttaaaact tacaccattt aaaacttttg cgtctttatt gtaggcaaac
     7621 tcaacatctt ttagatcaat atcaaatttt tttaagctat agtcatcgcc ttcttgtaga
     7681 tcttgatttt gaatttcttt taatctttct attttgggcg ataaataaaa tatttccatc
     7741 aagccctctt tagatgcatc taaagagtct tttatcttca tagcagctag taaatatcct
     7801 ataaggtaga gagaatttat ctctttatta ataattagat ttacgccgac aaatatcaca
     7861 acagcaagag atataaagct aaatattgaa gatatagaca aagttaaaat tgtagttact
     7921 tccgccttta agtgtactct ctcactatct tccatttttt tatataagtc atctttaata
     7981 tccttcgata aattatatgc tttaatctcc atttgcattt cgatattttc ttgaaagctt
     8041 tctgagtttt ttcttaagac atcataatat ctattctgtc cattaacctg atatttttta
     8101 gataaaggta taaatataaa gcttaaaata gatggaataa ttacagctaa acccatcttg
     8161 acattgcccg ctagcatcat tacagatatt aatgggaaaa acagtaccat gccgcccacc
     8221 tttggtattg agtggctcat tgcatgctct atgccttcaa tatcagccat gattgtttgt
     8281 gaaatgtcgg aaatgtcatg tttagaaaag taagatagag gtaattttga taaattctcc
     8341 gctgtcctta ttcttaaatc tgcactttct tgataggttg tgttatataa tttatcgtat
     8401 tcgatagaaa gcaaaatata cattgctatc aaagtcaaaa ctgagaatac tatataaaag
     8461 ccattgcttt tgcccatatt ttccaaaact tcctgagcaa aaatcataag taatatggca
     8521 ggaagcatgt ttatacaata aacgaaaaat gaagccagtg ttgctttact taaatttctt
     8581 gctcctccat ctgtaagagc aaatcttttt ttataaaact ctttcatttg aaaccctcca
     8641 ttcattcgca ctgttaaaca tctcttgcag gctcttatac cttgtatctt ttgacattaa
     8701 ttctttgtca gaccctcttt ctataatttt tccactatcc ataacaataa tttcatcaag
     8761 gtctttaatt gtagatagcc tgtgtgcaat catgataact gttttatcct tcataagatt
     8821 tttgaaagct ttttgcaatt caaactcgtt atctgggtca atagatgctg atgcttcatc
     8881 cataataata attttggaat cctttaaaat tgctctagca attgcaattc tttgtttttc
     8941 tccaccggat aaataaacac cttttgagcc tatgattgta ttttctcttt ctgggaattt
     9001 gtctaatatt aaatcgcatc ctgctaattt taaggctctc ataacgtcat ctttcgtcgc
     9061 atctttatta gctaaagcta cattatcata aatgctcttc ttgaataatt ttgaatcttg
     9121 aaaaacaaag gaaatggctt taattaaggc ttcgtcagaa tattcactta ttgctatccc
     9181 gcctatcttt atgcttcctt tattaacatt gtaaaaacct gatataagtt ttgctactgt
     9241 tgatttgcct gatccagatg aaccgacaag tgcgtaggac tttccttctt ctaaattaaa
     9301 ggataaattt tcaatgacag ctttatcatt ataagcaaag ctaacattct caaattctat
     9361 attatagttt ttaaaattat tgacattacc atgcactaat ttgtcttttt gcatatcttc
     9421 gtaaagcgcc tctaaagtat ctactgcata atttccttga gaaatataca tggagtacca
     9481 catcattctc atgaatgaaa caaagagaac tcctgataaa aataaaatca tgataagctc
     9541 aagtaaaatc acctttgcgc tagctaagct agtcataaaa taaactatag gaataattaa
     9601 aattgcaatc agtccaaaaa ataaccattg atacaaaaca taaggccttt tacaagatag
     9661 ggaataatca taagcatact ttgagtaatc gtttatcgcc ttataaaagc ttttaaaaga
     9721 ctctacattt gctttaaata tttttacaac ttgcattcct ctaacgtact cgacagtctc
     9781 agcacttagt ttagataggg attcttggta tatcttcata aattcttgct cgcccatcat
     9841 tgcccctaaa attaagccac caattatagt aagagcaagc aaaattatgc caactcttat
     9901 acttactata aagccaagtg caagtacaag tacgggtgtg attattgcct gagaactatc
     9961 gggaatcatg tgtgctacca cctgatgagt ttgtgctgca ttatcatcta tgatctttct
    10021 tatttgacca gatggattta agtcaaagaa cctaaaactt gctttttcca gaccatcgat
    10081 tccccttttt cttaaatttg tttcaagcct aaatcccaag atatgtgaaa acattcctga
    10141 gacaaaataa aatatcgctc cacttgttag tgtaataaca gattttaatg ctatactctc
    10201 tgcaccggat aagtttgaat taattattaa cttatctaga aatttgtaga ttaaataata
    10261 tccatatact gtaagtagag cagatatagc agaaaaaatt atggccaaaa ccccaagata
    10321 tttcttatct tggacataag caaatagttt tttgtaaatc ttcataagca tatctccttt
    10381 ctttaatatc ccttttagat ataaattcgc ttaattgata atatctatca ttgcttttct
    10441 attatacatc tgttataatt actaatacaa tagttttgaa ttaataaggc taattggaat
    10501 attgtctaaa agggatagtg tgttatgtca tattatgatt ttgtaaaaga ttatatgaaa
    10561 gtagatgaat gtaaaaacaa tgagaagtat tcaagtgcag gtcatacatt ttgttggaaa
    10621 aaagagaatt caacttatgc agaaggccta tattggtttt atgaaggagg cagcttcatt
    10681 atcgatatac atgattttta tatcaaagag gaagtagttc aaaatagcac ttatagtatg
    10741 tcagactatg tttcaattta ttcaagttac attgtcagtg caaacggaga aaagtttaat
    10801 ccgtatcaaa ctattaccgc aaactcttta tgtacttttg attttgataa tataaaagat
    10861 gattttgttt ttttattaca cgagaattgt tgttatcttg ctgtttccat tggttttaaa
    10921 aaagagctaa tagaaaaaca tttagcatct attaacatta atccagaatc tttttattca
    10981 accttgcttc aaccgaatca aataatactt acaaaggcct tagaaagagt ggcaatggaa
    11041 atattaaatt gtaagatgga cgctcctgcc gctgattttt tctttaaagc aaaggcaaat
    11101 gaatggataa gtatagtaat tgacacatac ttaaatagaa aaaaatataa aattgaaatt
    11161 gatgatgata aagcacttga agatgtagca agattcttag atgatcattt tgcaacgaat
    11221 gtaaatcaag gcacgcttga aaaaatatct aaaatgagtg gtactaaatt aaaaaattta
    11281 tttaaggaaa aatattgtca aagcattaca gagtacactc aaagaaaaag aatgaatgta
    11341 gctgaaactc ttcttttaaa cactgaacta cctataaaag agatagcaga atctgttgga
    11401 tattcatctg ccagcaaatt ttctatctat tataaaagat acaagggaaa acttccaagt
    11461 gaagtccgta atttagcttg caaacatcac aattttaaat gcgattattg tgattaaagt
    11521 aattttttac aagccatgtt tttatatgaa tttaagtgta tatgtgcata tatagtctga
    11581 ataaatttga tttgaaaaat ggataaaaaa ataaaggcag tccgaagacc gccaatattt
    11641 atctctctgc acctttgcta tggtctttct tatttgactt agatttgtca tctgtcttaa
    11701 agctttttat ttgccctaat atggactttt tatccttgtc ttgactcttt acttgttctt
    11761 ttgcttttaa gagcttagaa gacaaaaaga gatattatat taaaacaata tttctccggt
    11821 actgggactg ggacgggact aaaaatctga aaacgtccta taattaggtg gatttagtga
    11881 tattataaaa aatagaatct agtattttga atggttttgg atatattgta cgtttggaaa
    11941 agaagaatgg gagtaatttt aaactaacaa aaaatgcttt gaaatcagtg tttcagagca
    12001 ttttttgtcc aaatgtaaat cacttggaac tattattcaa tttattcttt ttagtaaatg
    12061 ttcccgtttt aatcccagtt acagttttta atcctctgta accgttgatt ttacaaagct
    12121 tttaattttt ttgcgattac tcccactcaa ctgttgcagg tggtttactt gtaatatcgt
    12181 agacgatacg gttaacatga tccacttcat ttacgatacg tactgagatt ttttgaagta
    12241 cttcccatgg aattttggca aaatcagcag tcataccatc gatagaagtg atagcacgga
    12301 ttgcaatcgt gtagtcatac gtacgaccgt cacccataac accgactgaa cgaacgcctg
    12361 tgttaacagt gaagtattgc caaatatcgc ggtcaagtcc agctttagcg atttcttcac
    12421 gaagaatagc gtctgattca cgaacggttt caagtttctc ttcagtgatt tcacccatga
    12481 cacggatagc aagtcctggt cctgggaatg gttggcgcca tacgatatgg tctggcatac
    12541 caagctctgt accaagagca cgaacttcat ccttgtaaag agtattgagt ggttcaatca
    12601 attcaaactg catatcttct ggaagaccac ccacgttgtg gtgtgacttg atagtttgag
    12661 ctgtatccgt accagactcg ataacatctg tatataaagt accttgagca aggaatttca
    12721 catctttgag cttgcttgct tcgtcatcga atacatagac aaactcgtta ccgatgattt
    12781 tacgtttttg ttcagggtca gaaacgccag caagtttgtc aaggaaacgt ttagcagcgt
    12841 ctgctttgac aatattcaaa ccaaacttac caccgagcat gtccataact tgatcagctt
    12901 cgcctttacg aagaagaccg tggtctacga agatacagat caattgatcg ccaatcgctt
    12961 tttggagaag aaccccaacg acagatgagt caacaccacc tgatagacca agaaggacac
    13021 gtttatcacc gacggtttca cgaatttttt tgatctgcat gtcaatgaaa ttatccattg
    13081 accagtcacc tttagcctta caaatgttaa gggcaaagtt acgaaggata tcatttccgt
    13141 atacagaatg acgaacttct gggtggaatt ggataccgta aatgtgttta tctgggtttt
    13201 cgatggctgc gtatgggcag tcagctgatg tacctgtacg aacaaagtca gcaggaatct
    13261 cagtaaccgc atcaccatgg ctcatcaaaa cagtctgttc atcaggtgtt gattcaaaaa
    13321 gcgctgatgg tgtgtgagtt agggttgatt gaccgtattc acgatttcca gcatcacctg
    13381 caggaacaac ttttcctcca agtttatggg tcaataactg cataccataa cagattccca
    13441 aaattggaat tccgagttcg aagatttctg ggtcaatatc aaatgaacca tcttcatata
    13501 cagaatttgg accacctgat agaataattc ctacaggatt gacttcacga acttcaacag
    13561 ctgaaatttt atggcttttt agttctgaaa aaacaccaat ctcacggata cggcgtgaaa
    13621 tcagctggtt gtactggcta ccatagtcca atacgatgat tttttctaca tcttgcaaat
    13681 cagttgaaat gttgctcatc tttttccttt ctcaaaagaa atatcttttc tcaatattct
    13741 atcacaaata agggcgaatt accaactaaa caaggcgaag tttgactttt tctagtttat
    13801 tggggtacaa tagagaaaag atagaaatga agtgaaaaat atgctacctg cttatatgaa
    13861 aatccatgat cagataaaaa aggatattga cgagcaccgt tgggctattg gtgagaggct
    13921 tcccagtgaa agagatttag ctgagcagtt tgcggtcagt cgcatgaccc tccgccaagc
    13981 tgtatctcta ttagtcgaag aaggcgtctt agagcgccgt gtaggaagcg gcacttttgt
    14041 ttccagtact cgagtacaag aaaagatgcg agggacaacc agttttactg aaattgtcaa
    14101 atcccaaggt aaagttccct ctagccagct catttcctac aaaaaaacca ttcccaatga
    14161 gcaagaagtt gccaagctag gaatttttcc aacggacaat attatccgaa tggagcgggt
    14221 ccgctatgcc gaccaagttc ccctagttta tgaagttgct tctattcctg aaaaattcat
    14281 taaggacttt aaaaaagaag aaatcaccag tcatttcttc caaaccttgc aaaaacatgg
    14341 ctatcgtatc ggcaaatctc aacagaccat ctatgctcgc cttgctaaag aaaagattgc
    14401 ccactatttg gaagttgaaa aaggacatgc tattcttgga ttgacccagg tttcctacct
    14461 agaagatggt actgcttttg aatacgtaaa aagtcaatat gtaggcgaac gctttgaatt
    14521 ttatcttgaa aataattaga ttaccacgca aaaactctct gtcacggaca aagagtcttt
    14581 tttatttttc taagaataaa tctttcaaag aaatcaaagt tacagcaaac aatatcattg
    14641 ccataccaag aaaatcaatg gtataaaatt gttcattcat tattaagaag gcaaagaaaa
    14701 ccgccgatat tggctcaatt gaagccaaca agcttgactt gaccggtcct atcagactgg
    14761 ctcctttaag gaaagctgta taggcaaaga cagtcccgat aaggataatg cctgcaaacg
    14821 caaggagaaa atcaagacta gtcgggatat cggcctgtag aacccctgta aaaggaaggg
    14881 cgaccaaacc tgctatgacc attcccacac caatgatcaa gctgctcccc cactttttaa
    14941 tcaaggctat gggtaaaatg atatacagag cataagtcaa ggcagaaaag agaccccaga
    15001 acaggccagc aggtgtcatg gataactggt ccaactgccc atgtgttgcg atcaggaagg
    15061 ttcctccgat ggcgaatatg atggaaacta tctctcccag tgtcggtgcc accctatcct
    15121 tgatacagct ataaattaaa attccgacag gacaaacata ctgaagcacc gtcgctgttc
    15181 ccgcattggt ctcctgaata gcagacagat aggcgaattg gttgagaaaa agaccaatca
    15241 gagcaaaaat aagaagagac agcaaactct ttctatcctt taaaaagacc agtattttat
    15301 cctttgcagt agcataagcc aagagcatga gagttccacc agcgattaaa agacgcaagt
    15361 tggtcaagac cagagccgaa attccgtgtg ccatcaggta ttggccactc gttcctgaca
    15421 acccccaagc aataccagcc acaactgtta gtaaagtccc ttttaaacta tttgacatgt
    15481 ctctccttac tcttctttgc gaatcaagtt catcacttga ttgcgatcta atatccattg
    15541 agctctctcg tccttttcat aggtacgatt cgataggaaa atagtggctt cttgcttctg
    15601 acgattccac atgataaagg tacctgtata gcccgtatgg tctagccaat ctccttccaa
    15661 attccatgct aaagaacgtt ccttgtcatc caaaggagaa aaattttgat ttaagtctct
    15721 tgcaaaatca tctgctaaat agtgttctaa aaagatttgt aaatccttta tagtcgaaaa
    15781 taaaccagca ctcccagcat gtctacccag gagacgagcc ttgggatcat gcactatgcc
    15841 tgcctctaca cctctaactg ttggaacagc aagctcaact ggcccaaact tagtttccgt
    15901 cattccccaa ggtttccaga cttgatcctt taaaatcaca tccaaatctt gattaaaaat
    15961 tctttccaaa ataaagccca acagcaaaaa atggacatcc gaataaagaa aggctggctg
    16021 acttcgtctg ttgagatgaa acatcgcttc ctttaattca ggggctgtta aaagatcacg
    16081 attaggaata aaaggatcaa ggtctgttgc atgagtcaag agctggcgaa tagtgatgtc
    16141 tggataatca ctctcaggta aaaaatctat taccagtcta tcaatatcta attgacctat
    16201 ttcccacaag aaggtacaaa ctgtgccaac cccaacaacc ttgctgacac tagctaggtc
    16261 ataaactagt cctgcctcag tctgcaagcc atgctctggg tcactctggc ctaaatagaa
    16321 ctctgtccat tgattgtcct taaaatacgc aaaagaggct ccgggataaa ttcctgcctc
    16381 gatttgttct tctatttttt taataatctt ggtccacttc atacttcttc aaaccacaat
    16441 tcaacattat ttctatcttt accaaggaag aatttttcag acttaggaat aaaatattca
    16501 gtagactcaa acttctggcg aagacttgct atgtctaatt cattgaccaa gaacttgagc
    16561 atagataagt cccaggtaac cgtattgtcc acagtcaaat cctgcccctg agctggaata
    16621 aaatcaaggg atgccccaat ttcagatgat tccaagaaac tttcgatatc agttgggaga
    16681 tgtaattcca tagaaatctc aaatttactt aaagaaattg atgccaaatc tatttgaaat
    16741 tcaggctttt ctcctacttc tactagactt gctctgtcat cttccgcatg aatcaaaatc
    16801 aaatcatctt ctggtgagaa aatttcaaaa gcgtagccat tttgaccttt atataatcga
    16861 tgaatcgaat ctgttttaga taagattcct tcaatttcta agggattttc caccttgaca
    16921 atcaatctag ctagtttttt tcttccctct accttacgag tacgcatact gggagcttct
    16981 tctaaaacca gcttttcaag acccgtttgg tcacctagtg acagaaaggc cgattcttct
    17041 aacaaggcct tcattccaag ggtttcaata taaaatgttt catttaattt tctattatta
    17101 gcttttaaag taggaataat ccgtacaatc tgatttacat tcataaattc ctccgtcact
    17161 ttttatttta aaggatttta gaatttttta caagatatta tgctcaaatt taacattatt
    17221 tagctattta gtaaagatag tctttcaaga attttgacaa agcctgataa ccagcaatac
    17281 tgaggtgcag tccatcagtt gtatattctt ttttgagttg gcctgcttgg tctgtcaaac
    17341 aatcaaatac tggcacaaat tccacctgca tataggcaga tgcaagctct tgataggctt
    17401 gattccagtt ctgaattttt tcattcgagc ggatatagac tgcctgctgg tactcctctc
    17461 cctcattgac aggcaaaatg gaaagcaatt taatctctgt caatggataa tcgcgagcaa
    17521 cggattgaat gatagcttcg agattattga gagcctcatt cacaggaaca tcctttccga
    17581 tatcatttgt cccaatcaga agaaaaattt tatctactgc tccaccatat agatgagcat
    17641 caagattctc tagtaacagt cctgtctgat agccacgaat tcctcgattg acaatcgtct
    17701 ttgaagtccc aaatagctcc tgtagaggat aatactcgac aatggaatcc ccaataaaaa
    17761 gaatgtttgg ttctacaaca gaaatgtgat ttaggtgacg atacttagtt tgaatttttt
    17821 cttgttcctt taggagccaa ttttctaata actgtactgc cacttcattc tcctttttct
    17881 aaccagtttt ccaagacttg ataaactcct ccttggctgt tggctggtgc tagagcagtc
    17941 gccacagctt tggctttctc atcagcattt tccatcgcat aggcaattcc agccatttca
    18001 agcatttcaa catcattttc actatcacca aaagccatga tttcttggga tttcaagtcc
    18061 cagcgcttga gtaattcctc caagccccat gctttatgaa tcccagcttg gaggatatca
    18121 atgcaaccat agccactgga tacagctcgg acacggccat caaagagagc attgatttct
    18181 tccaaaaccg aactcaaacg ttcctcacca acaaccatgc tcatcttgag cacaccacca
    18241 aagaggtcag atgttaattc atccacaaat tgcatccgtt ggtagaattt ttcaatcatt
    18301 tctggagtca taaaactttc aagatctgta aaaatcgtac cttccttgac aaaatcaccc
    18361 ttcatccccg ttacaacaaa ctggtcctga cacgctcgaa ccttgaaatg agtcaaagcc
    18421 ttgttgacaa tggcgtcatc ccatgtctga gcctgaatca attcattgtt ttcaaaaata
    18481 cgagcgccat tagcaacaac cagaaccact cgatccacca agggactcag tagttgtctc
    18541 atgcggtgaa tttcattgcc cgtcgcaatg acaaaacgaa tgcccctttg atccaactga
    18601 tctaaaatct tttccaatcg tgggagatca agctgacctc tagcatccag caaggtccca
    18661 tccatatctg tcgcaattac cttaatcatc atttactttc ctctggattc aagctaatac
    18721 cacttcaatc ccacatgttc attcatttct ttataggctg tatcaattcg ttccttagtc
    18781 gcttcatcta actggtcaca atgactgcca tcctctataa aatcttccaa aatataagtt
    18841 tggtaatgat acaagggata tccttctggt gaaaaggttc cctttggtgt tcgattgacc
    18901 taagtaggat gagctttagc tgttccgata gttgtttttc catccttctt cttgatggtg
    18961 acatccatga gaacaccacg ttcagtccac ttagcattct cttcatctcc catagattca
    19021 atccgttgat tggaaatgaa gttccccatt taatagataa tgagtttctt atctccatct
    19081 ttttcaaccg tttcagatgg ttcaacaacg tgaggatgcc ctccaaagat aatatccgct
    19141 ccccaatcga tcatcttgtg ataaagagct ttttgttctt cagttggttc caatcgatac
    19201 tcaacaccca tctgaggcat gataatggtg atatctgctt ccttctctgc ccgttcaact
    19261 tcagccttta tcttatcttc gtttaaatct gaaagataac gattatagtc ttcctgaaaa
    19321 atatactgct caattccatt gaaaccatag gaataggcta acaatgcaac cttgatagca
    19381 ttcacttcct taatgaccag cggagcctga tcacgtggtt cgtgcgtata aactctgatt
    19441 ggagtgattc cagctttctc aataatatcg gccattgaaa taactccctc aatttgcgaa
    19501 tccaaaatat gattatgagc taaatccagc acatgataac ctgcttcctt aatagcatcc
    19561 ataacttcaa caggagcatt aaagagaaga taacccgcta aataatgatc cttattaatg
    19621 gttccttcaa aatcaccaat agctaaatct gcttgcttga gccaaggagt cacatactca
    19681 aaattttcat gaaagtcata ggtaccgtct tcttttttag ctgaaaagaa aagtccatcg
    19741 tggtagagca aatccccgtg ggccataatt ctggcagttt tttcctcttc ctactcctga
    19801 gacttttgct tagtcccctc ttgagaaata gtatctcgtt tttgactagt caagggattc
    19861 cttggaagct ttcaaacaac aagaccaagc ccattgataa accaactgcg agcaagagta
    19921 tcgccacaaa tcccttattg ctccacttgc gataactcct aaaaagttta ccaagccctt
    19981 cataaaacga aaagctaaac caccctgatt tcgattttgt cttctttgta tcttcattct
    20041 ccctactttc ttatgcaagc cttttctttt tattatatca cagataagta tttctttcac
    20101 aattgaattg aacttcccat ctattttcta taaatcctaa atgccataat gctttcaatt
    20161 cttgtcattt tgtgatatca tgtagaggta atgaaaggaa atgaactaat ccacagtggc
    20221 ttattccaag tataccactt gggctttggc agtagttaac tgcactaaac ataatataag
    20281 gagagaaaat gtctgcaata gaacgtatta caaaagctgc tcacttaatt gatatgaacg
    20341 atattatccg tgaagggaat cctactctac gcgcgattgc tgaggaagtc actttccccc
    20401 tatctgacca ggaaatcatc ctaggcgaaa agatgatgca attccttaaa cattcccaag
    20461 atcctgtcat ggctgaaaaa atgggactcc gcggtggtgt tggactggct gctccccagt
    20521 tagatatctc aaaacgcatt atcgctgttt tggtacctaa tattgttgaa gaaggcgaaa
    20581 ctccacagga agcctacgat ttggaaggca ttatgtacaa tccaaaaatc gtctctcact
    20641 ctgttcaaga tgctgctctt ggcgaaggag aaggttgcct gtctgttgac cgtaacgtgc
    20701 ctggctatgt tgttcgccat gcccgcgtta ctgttgacta ctttgacaaa gatggagaaa
    20761 aacaccgtat caaactcaaa ggctacaact ccattgttgt tcagcatgaa attgaccaca
    20821 ttaacggtat catgttttac gatcgcatca atgaaaaaga tccatttgca gttaaagatg
    20881 gtttactgat tcttgaataa agaaaatccc gttgcaagac ggggttttgt gttataatag
    20941 aggcatgaaa acaaatgata ttgtctatgg tgtccacgcc gttaccgaag ccctccttgc
    21001 aaatacagga aacaaactct acctccaaga agatctccga ggtaagaatg ttgagaaagt
    21061 caaggaacta gctacagaaa agaaggtgtc catttcttgg acatcaaaaa aaaatctctc
    21121 tgagatgact gaaggtgctg ttcatcaagg ttttgttcta cgagtgtctg aatttgccta
    21181 tagcgagcta gattacatcc ttgcaaaaac acgccaagaa gaaaattcac ttctattgat
    21241 tctagatggt ctaaccgatc cccataatct gggttctatc ttgcgaacag ccgatgcgac
    21301 caatgtttca ggtgtcatca ttcccaagca ccgtgctgtc ggagtaactc ctgtcgttgc
    21361 caaaacagcc acaggtgcta ttgaacacgt tccaattgcc cgagtaacca acctcagtca
    21421 aaccttagat aaactcaagg atgaaggttt ctggaccttt ggaacggata tgaacggtac
    21481 tccttgccac aagtggaata caaaagggaa aatcgccctc atcattggaa atgaaggaaa
    21541 aggtatctct agcaacataa aaaaacaggt cgatgaaatg attaccattc cgatgaatgg
    21601 acatgttcaa agccttaatg ccagtgttgc tgcggccatt ctcatgtacg aagttttccg
    21661 aaatagacta taaaaaagtt tccagtcatc tgattggaaa cttttttatg attaactatg
    21721 ttctgtaatg aatttatagg cttcttgacc agcgatagct ccatctccaa ctgctgttgt
    21781 tacttggcga aggtctttca agcgaacatc tccaactgca aagataccgt cgactgcagt
    21841 cttcatgtgg ctatctgtca caatccagcc tgcctgatct tggatattca attctttaac
    21901 aaaatcgcta agagggtcca aaccaacata gataaagaca ccaccgaagg cttgctctgt
    21961 cacttgacct gttttcacat tttcaaaaac gacagattct actctgtttt cacccttgat
    22021 tttccttact acagaatccc atataaagct gattttctca ttggcaaagg cgcgatcttg
    22081 taaaaccttt tgggcacgaa gttggtcacg acggtgaaca atggtaacag tcttagcaaa
    22141 acgagtcaag aagagggctt cttcaacagc tgaatctcca ccaccaacta ccaataaatc
    22201 ttggtcacgg aagaaagcac catcacacac agcacagtaa gaaacaccac gactgttcag
    22261 ttcttcttct ccaggcactc ccaaaggacg gtgtttagaa ccagttgcta cgataactgt
    22321 acgtgtttca tatgtttggt catcagtcat cactttctta aaatcaccat ggtcttcgac
    22381 attttcaaca taaccataaa tgtgctcaac accaagattt tcaagtggtt caaacatctt
    22441 ttcagccaat tcaggtccac taatattagc gtatcctggg taattttcga tatcagatgt
    22501 attattcatc tgaccacctg gcagaccacc ttcaatcaaa gctactttta gattgcttcg
    22561 agcagcatac aaggccgcag tcatccctgc aggtccagca ccgataataa tagtatcgta
    22621 catatagatt ccttctttct tgttgtaact atctttattc taactctttc ttgtcaatca
    22681 cgcaaggatt atgccttgaa aacaagaatt aaactcataa ccgcaaagga taatactggg
    22741 acaaccaaga ctccaatcat aatcatatca tagagatggg cttggcgagc cttggctgtc
    22801 ttatcaactc ccgacatggc tctcagacca atccaaatcc ctaaaaaaat cagaacaagg
    22861 atggtggtca agatcaaact ctcgaaatat aaagaaaata gttgcagtag catgatttct
    22921 ctcatttcta tcttttttaa agagtaaact cagctagtcc aactaactga gttttccttt
    22981 atctattata tcaaatataa gtccgtttgt aactagcgaa gaattctttt gtccgctctt
    23041 ctttaggggt gtggataatc tcatccggag ttccagactc gatgattttc cccttatcta
    23101 agaagagaat cttatccgca acttgggcta caaaggacat gtcatgactg accaaaatca
    23161 tggtctgacc tgacttagca gcatctgcaa tagacttttc tacttcaccg accaattctg
    23221 ggtcaagggc tgaagttggt tcgtctaaga gcaaaacatc tggtttcata gcaagcgcac
    23281 gcgctagggc aacccgttgc ttctgtccac ctgataaatg gcgaggataa tggttttcac
    23341 ggtccgaaag cccaacctta gccaactctt ccttggcaat cttagtcgct tcttggtcag
    23401 ataatttctt gacaacaacc aagccttctt tcacattatc aagtgctgtt cggcgttcaa
    23461 acaaattaaa ctgttggaaa accatagaca acttacggcg tagggcaagg atttcttctt
    23521 gagtgatttt agaaaaatca actgaaaaac catcaatctg aatagagcca ctgtcaggtg
    23581 tttcaagata attgagactg cgaagaaagg ttgattttcc agctcctgaa gaaccaatca
    23641 aggctacaac ttcccctttt tgaatatcca agtccagatg atccaagaca gtctgtcctg
    23701 aaaaggattt gcttaaattc gaaatcttaa tcattaacga aggtctcctt tcacatctgt
    23761 ttgcactgta tcaggtgcag aaatagccat ttttctctcg atgaaacgac cgagactttc
    23821 aattccgata ttgactaccc aataaacaag ggcaacggag atgaagcgtt caaaatagcg
    23881 ataatcagct ccacctagaa tctgagcttg ggcaaagact tccacaacac ccgcactaaa
    23941 agctagagat gttcccttgg tcaaaccgat gagggaatta atcaaggttg gagtagctac
    24001 caccgctgca ttaggaataa tcactcgtcg ataaacttgc gctcgggtca tacccagact
    24061 gcgtgccgcc tcaatctcac caggattaac tgagagaatg gctgcacgaa tggtttcact
    24121 agcataagct gcctcattaa aggcaaaggc gacaatcgca aaagctgcag ctggaatcgc
    24181 attgatattg agaccagttc cccattgctg attgagggct ttcaaagcca aagggattcc
    24241 gtagtaggtc aacatgagtt gcaccaaaat cggtgtccct tttaagaaac taacaaagaa
    24301 ggcctgcaag ggatataaaa tcttgacacg attgatcttc acaatggcaa aaagaagcgc
    24361 caaaaccaag ccaaaaaggg caccaccaat tgtcaacata attgttgttg gaagttgttg
    24421 gacaattcta gggattccat caaagaccga acgtaggcta aacagcttgc cattcggaat
    24481 caattgcatc aagttttggt accaatctga tgctaaaatc gttgtaacat tcataaaaac
    24541 atcctcttct gataatgatt cattctacca tgcttctgcc gtcaatgaaa ttatttgcta
    24601 cggtcagata cagactttgt ctacctacta gtttatcata ctttgaaaca gggaagttat
    24661 atattttatc tatcaaagag atagataaaa actatttcag tcccagttct tcataagatt
    24721 ttcgataacc gatttgctta acggttccat tttctactaa aatgggccgt tttaacaaca
    24781 taccgtcact tgctagcaac tcagccgctt cttggtttga caaacttcct accttatctt
    24841 ttagccctaa ttcacggtat ttgataccac tggtgttgaa aaattgcttc aattcaaatc
    24901 ctgaggtttc tagccaattc aaaatgactt cttggctagg tgtttcttcc acgatatgga
    24961 cggctttata gtccacacct aattgattta attcttgttt tgctttttta caagttgaac
    25021 atttggggta ttcgataaat tctaacatgt gcttctcctt ctattgcttc tatctttaaa
    25081 atctactcct tcatgctcca agagccaagc tttcttttcc actcctgcag cataacctgt
    25141 cagacgcttg cctgctccca acacacgatg acaaggtact aggatagacc aaggattgcg
    25201 tcccactgct ccaccaattg cttgagcaga agccacttgc aggtcttgag caatttgtcc
    25261 ataggtcact gtctgaccat aaggaatgcc ctgtaaatag tcccaaactc tcttttcaaa
    25321 attcgttccg attggcgcca agagcaagtt ggataaatcc tgaggcttgc ctttaaagta
    25381 atcatctaag caagcaataa ctgggtctaa aataggatga ctaacaactt cttctatcgt
    25441 ttcatctcct agtcccctct caaaatgctt ctgctcctga acccaaattc catacaaata
    25501 atggtcatca gctacaagtg atagaatacc aattggtgag gagtagagta tttttacata
    25561 cttcttttgc attatttctt taatttttga taggccaagc gttcgccatc tactggcacc
    25621 ttaccaactt gtttaaaacc aagtttttca aaaatatgtt gcataacctt gttttcagca
    25681 tgcgtatctg agcgaaaatc aagataatca aaaccttcaa tcaagccctc taagaaggtt
    25741 tgagcaactc cttttccctg cacatctgct gccacagcaa tacggtgaaa gactagatac
    25801 tctgactctc cagcttgcca gtttccctca taaatagctt cataggcctc ctctggactc
    25861 ttggtcacag cagcataggc tagcagttct ccctcttcca aggctacgta ggcttgccct
    25921 gagatgatat catcgataat aacatctgca tttggatagc cattttgcca ctggtcacta
    25981 ccagcatctg ctaaacattt tttggcatcc tccatcacct gcatgatggc atctacttca
    26041 tttggaaaag ctaaacgaat ttccatcttt tttcctcatt tctgactagt ttctcccatc
    26101 atagcataat ttaagtattt ctacaagcag ttaaaacttg actttgtgtt tttgttattt
    26161 tataatctag ttatcaaaac tatataaaaa ggagttgaaa atgaaaacta ccttttccta
    26221 cccaaaatgg gcagaaattc caaacattga cctctatctg gaccaggttt tgctctatgt
    26281 caatcaggtc tgcgccccta tctctcctaa taaagacaag ggcctaacag catctatggt
    26341 caacaattat gtgaaaaatg gttacctgac aaagcctgac aaaaaaaaat accaacgcca
    26401 acagattgcc cgtttgattg ctatcacaac cctcaagtct gtattttcta ttcaagaaat
    26461 agcccagaca cttaatactc tacaaactca agcaagttca gaccaactct acgatgcttt
    26521 tgtggactac atgaaccaag gaattgaccc agctaaccct attatccaaa ccagctgcca
    26581 aaccgttaaa ctctatcatc aaactctaga cttaatcgat catactcaag aggaggtaat
    26641 ccaatgaaca ctagtcttaa actcagcaaa caactcagtt ttggagagga gattgctaat
    26701 agcgtgaccc atgctgtggg tgcagtcatc atgcttatct tgctgcctat ttcatccatc
    26761 tatagttatg aagcacacgg atttttatcc tctatcggcg tttccatttt cgtcatcagt
    26821 ctctttctca tgttcctatc atccaccatt tatcactcta tggcctatgg ttcgacccac
    26881 aaatatgttt tgcgaatcat tgaccattct atgatttacg ttgccattgc cggctcatac
    26941 acgcccgttg tcttgacctt gatgaataac tggtttggct atctgattat tgtcatccaa
    27001 tggggaacga ccatctttgg tattctctat aaaatctttg ctaaaaaggt caatgagaaa
    27061 tttagccttg ctctttacct gattatgggc tggttggttc ttgctatcat tcctgccatt
    27121 atcagtcaaa cgacacccgt tttctggatt ctcatggtaa ctggcggact ctgttataca
    27181 gttggagctg gattttatgc caagaaaaaa ccttatttcc acatgatttg gcatctcttt
    27241 atcctagctg cgtccgtact ccaatacatc gctattgttt attacatgta aaaaagttga
    27301 gaaattcaat ctcaactttt ttctttacac atattgataa agtactggtg caagcgcaca
    27361 tcatcagtca attctggatg aaaagaactt accaacatat ttttttcttg ggctgcaaca
    27421 atttgattgt tcactgttgc taaaatttct acaccctcac caacactact gataatcgga
    27481 ccacggataa aggtcattgg aatcttgcca actcccttac attctgcttc cgtgtagaaa
    27541 cttcctaatt ggcgcccata agcattacgc tcgaccacca tatccatagt tcctagatga
    27601 ctctctttct gagaagtgat ttccttagcc agcaaaatta agcccgcaca ggtcccaaac
    27661 actggtaagc cagatagaat ggcttctcgg atgggaagta gcatgttctg gtcacgtaag
    27721 agcttgccca tggttgtaga ctcaccacca ggcaaaatca aacccgacaa gtcactctga
    27781 tcttgctgaa aatcatctag atttctgagt tctacactct cgacacctaa ttgatctagc
    27841 acttttgcat gttctgcaaa ggccccttgc aaggccaata ttccgatttt catctatttt
    27901 cctcgttcag ccatgagaat ttggatttca ttttcattaa taccaaccat ggcttctcct
    27961 aaatcttcag agatttgagc taggatttga ggattacgga agttagtcac agccttaaca
    28021 atggcactcg ctcgtttaac aggatctcct gacttgaaaa tacctgaacc gacaaagacc
    28081 ccctctgccc ctaattgcat cattaacgca gcatctgctg gcgttgcaac acctccagca
    28141 gcgaaattta caactggcaa ttttccatgt tcatgaacat attggaccaa ttctacaggg
    28201 acttgcaaat ccttggcagc aacataaagc tcgtcctcac gtaagttttg aatgcggcga
    28261 atttcctgat tcatcatacg catatgacga acagcttgga cgatatcccc tgtccctggt
    28321 tctcctttgg tacgaatcat ggaagcacct tcagcgatac gacgcaaggc ttcacccaaa
    28381 tccttagcac cacagacaaa aggaacttgg aattctttct tgtccacatg gaaacggtca
    28441 tcagctggag atagaacttc actctcgtcg atataatcaa tttcaatagc ctctaaaatc
    28501 tgagcttcaa caaaatgccc gattctgacc ttagccatta ctggaatact aaccgcttct
    28561 tggatttcct taatcatctt tgggtcgctc atgcgggaaa ctcctccagc tgcacgaata
    28621 tcagccggaa ttcgttccaa ggccatcaca gctgccgcac cagcagcttc tgcgatacga
    28681 gcctgttcag gattctgcac atccataata acaccaccct tgagcatctg tgccaagttt
    28741 ttatttagtt cataacgatt ttcagtcatt tgttttatcc tcatcatttg tattggtagc
    28801 taccttttca ttttaagtca gaacagaatg aagcacaaga taaaaaaact ataattgtat
    28861 ggggacagat tggctaaaaa ctatctgacc ttaacttaag gccagatagc tcattcattt
    28921 ttatttttca gccgtaaggg cagccattgt gatgtagttg tatggtttgt tgaagtgtgg
    28981 caagaagaag aggtctgtca atgccaattt atcaattgtc acatgctctt ggatagcaag
    29041 tgagaacatg tggattccca tgctaattgc aatatcatgt gaaaccattt gggcaccaag
    29101 aatttcacgg ctatctttgt caaagacaat cttaattgct acttcatggt tgtcatgttt
    29161 catgaattct ggtttttgaa gatcgttaaa gcctgtttca gttgcgttgt aaccagcagc
    29221 tttcgctttt tcaagagtca aaccagttga aaccatgtga agaccgtaga ttgagatacc
    29281 atttgaacct tgaacaccga ttccttccaa ttcatgtcca caagcgttgt aggcaccaac
    29341 gataccagtg cgaacagcat ttgaagcaag agcgatatag cttgtatctt tacgagcatt
    29401 gtcataaaca gtcgcacagt caccaacagc gtaaacgcct gggatagatg tttcttgttt
    29461 cttgtctaca aggaaggcac cgttgcggaa gagttcgatc ttaccatcag caagggctgt
    29521 gtttggacgg aaaccaactg caaggataac catatccacg tcaaagcttt ctttgtcagt
    29581 aatcaagcgt tcaactttac cgtcaccttc gattgcttta acagtttgac ctagagccaa
    29641 gcggatgttg tgatcttcca agttcttcgc catcatttgt gtgaagtctt tgtcatagta
    29701 accgttcaag acagtatcaa cgatatcaac aaggacaact tcttttccaa gacgtccaaa
    29761 ggcctcagca agttcaacac cgatgtaacc accaccaaca acggcgatac ggtcgaggtg
    29821 ttggctcttg tcagaaagtt tattgataac ttcttcagca ttttggtaca atttcacgaa
    29881 ttgtacgttt tcaagagttg ctttaaattc gcggtttcct ttaacaattt caacaccttc
    29941 gattggtggc aagattggtg tagaacctgt agcgaaaatc aatttttcgt atgattcttt
    30001 gtgctctttt ccttcaactt ccgctgtaac tactttgtta tcatagtcga ttgaaagaac
    30061 aggtgagttc atgtaaactt tagcaccttt agcttccaat ttttctttat cagaatagaa
    30121 caagccttca gcaccgtcaa tttgttcacc aatccaaaga gccattccac atcctaggaa
    30181 agagatgtta gagttttggt caaatacaac aatttcgttc tcatttccaa aattatccaa
    30241 catggtattg atacatgctg taccagcgtg gttagcaccg actacaacga ttttactcat
    30301 aaaaatttcc tgccttcatt ctaaatttac cttactagta taccatttac cgttagcgtt
    30361 tacaaggggg gtactattat ttcagcattt tttatcaaaa ataattcccc atttatcctg
    30421 ttttcaagcc tcatgaattt tatgagcata tttcttgact ttttccaaat tttgtttgtg
    30481 aaaattctaa ctttatggta ttataataac atgaaaataa aatgtaaggg cttcaattta
    30541 gatgattatt tgatattaca acttattttc tataagagaa aggagttggt agcttgactc
    30601 ttcgttcaca ttctgaacgg ctaatgggga ctactatcac tatttcatta gtggatgagc
    30661 aagccgatat ctttctccaa aaatcctttg acttgctcaa agagcttgaa taccgcttca
    30721 acgccaatag tcaagaatct gagttgatgg aaatcaatta tcaagcagga atatcccccg
    30781 tcacggttca tccagacctg tttgagctga tttcacttgg gttagagcat agcctagcgc
    30841 tctctagcca cctcaatatc agcattggtc ccttaattca aacctggcgt atcggttttt
    30901 cagatgccaa ggtcgcccag cctcaagaaa ttgaatcggt gctgcctcta atcaatcctc
    30961 atggtatcga gttagattct tctacttcta ctgtgttttt aaaacagaaa ggaatgaaga
    31021 tcgatctagg ttgtttagcc aaaggataca gtgcggataa ggttgcccaa tttcttagga
    31081 aagagggggt gacttctgcc ttgatcaatc tgggagggaa tatcctgacc attggaaaaa
    31141 atcaggcaag aggggataac ccatggcaaa tcgggattca agacccagcc aatccgaggg
    31201 gaaatcattt aatgaccatc cctgttgtca ataaatctgt cgtgacttca ggcatttatg
    31261 aacgtcacct gaccgtcgat ggacaagatt accatcacat ttttgacagt caaacaggat
    31321 atcctgttga aacggaacta gcgagtctaa caatcatctc tgataaatca gtcgatggcg
    31381 aaatctggac gactcgactc tttggagaaa gacctgcttc tatcctctgg caagtcgaaa
    31441 gtttggaggg catcgaagtc atcctcatcg ataaagaagg ccacctaagc tgttcttcag
    31501 gaattcctac tctatagaga caactgtttc aatggaattt taaaattgta ttatgtaaaa
    31561 agagaaagga aatctcatgt taaaacttat tgctattgtt ggaacaaatt caaaacgttc
    31621 tacaaaccgt caattgcttc aatacatgca aaaacacttt gctgacaaag ctgaaattga
    31681 gcttgttgaa atcaaggcca ttcctgtctt caacaaacca gctgacaagc aagtacctgc
    31741 tgaaatattg gaaattgctg ctaaaatcga agaggctgat ggcgttatta tcggtactcc
    31801 tgagtatgat cactctattc cagctgtttt gatgagcgct cttgcttggt tgtcttatgg
    31861 tatttaccca cttttgaaca aaccaatcat gattacaggt gcttcttacg gtacgcttgg
    31921 ttcatctcgt gcccaattgc aacttcgtca aatcttgaat gctcctgaaa tcaaggcaaa
    31981 tgttcttcca gatgaattct tgctctcaca ctctcttcaa gcatttaacc caagtggcga
    32041 cttggttgac cttgatgtta tcaagaaatt ggatgccatc tttgatgact tccgtatctt
    32101 cgtgaagatt actgagaaat tgcgcaatgc gcaagaattg cttcgcaaag atgcagaaga
    32161 atttgactgg gaaaatttgt aagataggag accgaaagaa tgaaatttgt tggacttgtt
    32221 ggatcaaact acgatcaatc atataaccgc aaactcttgg aatttatccg tcgcaatttc
    32281 aaattcaaat ttgaattaga agtacttgaa atcgacgaag ttccaatgtt taaccaagac
    32341 gaaaaatggg atgaaagttt ccaattacgt tatttatata acaaaattac tcgtgcagat
    32401 ggtgttatca ttgctactcc tgagcataac cacactatct cagcttcact caaatctgta
    32461 cttgaatggc tttcatacga agttcatcca tttgaaaaca agcctgttat gattgtgggt
    32521 gcatcatact atgaccaagg aacatcacgt gctcaagttc accttcgtaa aatccttgat
    32581 gctccaggtg ttaatgccta cacgcttcca ggtaacgaat tccttcttgg taaagctaag
    32641 gaagcttttg ataacaacgg aaatatcacc aacgaaggca ctgttaaatt ccttgaaact
    32701 tgcttagata actttgttaa atacgtagga gtcgtttcga aattgaaaaa accaaaacca
    32761 atcgaatcag aagacttgga ttgtggaaaa ccaatcgcta caaccatcac agaagttgac
    32821 cctgacgatc cagaatgggt agaaaaagtt gcagcaatca ctggtgctgt ttctggtgat
    32881 acctatgtca aattggacca cggtatccta acagttaacc aaattgatat gttcttgaaa
    32941 gctatgccat ttgaattgac atacgctgac gacaacaacc aattcctcta ctacaacaac
    33001 gctcaccaag atccagacac tatgttcgct aaacgtgtac cacctcaatc aggtagccgt
    33061 atgtcgactg ttcatggttc tcttccacca gcacgtatga agaacgtaga gtgggttatc
    33121 ggaacacttc gcaacggaaa ccaagaatac gtccgtacga tcgttccagg ttctcctgca
    33181 ggtgttatca acactcacaa ctaccaagca atgtactatc ctgatggatc atacgctggt
    33241 atcaatgaaa tcgtctttaa cttccaacca tggcttgact ggtacctaaa agagactggt
    33301 caacgtttgg tgggtggtag cggaccattt gctcctgctg gcggacatgg tcacggcgat
    33361 gcagatgcaa catctggagc ttctgatgca ggtgatgctg gaggccacgg tggtggcgca
    33421 gatgccacag ccggtgcaag ttactaatga tagtttttag gaaccattat ggttcctttt
    33481 ttagcgaaaa aagactagca aacacaaact gctagtctct ttgttatcgt ttcatctatc
    33541 tttgttaaaa gatagaatac atattatgaa tttgggtcat caagactacg gccatgtaat
    33601 cctttttcac gttgtacttg gcgtagtttt tctggtgtaa catcgtttcc ttcttcgtcc
    33661 acaattttga ttccttcaat atggtgacga acagcgcggc gataaccttc gatgtactcc
    33721 tcacgtagtt tggcttgttc cactttttct tctggtgtta agccttctgt ttttttcttt
    33781 ttagcaagct cattgatacg agcaattttt ttcggatcca tttcttctcc tctgtaataa
    33841 gataaagccc gtttatcaaa ttttatttag tgttaatttg gttaaaacaa gcaaacttag
    33901 ctgctttctt ggttagttgt gacaagattg ccaaacgatt ttgacggaca gcctgatctt
    33961 cagccattac catagtattt tcaaagaaag catcaatgac tgggctaagc gcaaagagtt
    34021 gtttcaattg ctgacttgca ggtcctgata aaacgagtgt ttctactgct tctgccaaag
    34081 ctttttcttg gtcattctca aatagtgctg aatcaaccgt agcaacccct tctgccttct
    34141 cagccaggtt aaaggcacga gaaagtgatt caacagatgg tttaaaatct tcttccttgc
    34201 ttacttctac gagagcactt gctgcttcca acatatctgc cacaacaaag tttgaacctg
    34261 caagaactgc ttctttgata tcttttggag tagagcccat catcttatca acacgagcct
    34321 tgataaagtc cataacctct gctttatttt cataagtcaa actgtcaaat ttcaatgcat
    34381 aaaggctatc aatcagctca tccatagcaa tgtgccaacc aaaggcatcc aagatacgaa
    34441 ccacaccttg agttgcacga cgaagggcat aagggtcatt agaacctgat ggaatcaatc
    34501 ctactgagaa gaaactcaaa atcgtatcca atttgtctgc aatggctaga actgcaccga
    34561 ccttgctctc tggaagttct ccttcagctg atgtaggcat gtagtgttca cgaatagcag
    34621 ctgccaccgc tggagtttca ccagcaagaa gggtgtattt ttcacccata attccttgga
    34681 gttcgtcaaa ttcaccaacc atacctgtca acaagtcaaa cttgtaaatg gctgctgcac
    34741 gagcaaggtc aactgtttca tccactgaca aaccagcttt ttctgccaaa agtacagtga
    34801 tttgacccgt acgaatcatg tgttcacgaa gggaaccaat cttctcatgg aaggtgacat
    34861 tgtttaattt ttcaacaaga tctgaaatca ccaatttttg gtcttcacgc cagaagaatt
    34921 ctccgtcttc caagcgggct accaagactt tttcatttcc tttgatgaca tttttcaaac
    34981 gctctgcgtt tccgttacga acagaaatga agtttggcaa gagttttcca tcttgatcac
    35041 gaacaacaaa gtaacgctgg tgttccttca tagaagtcac caagacttct tctggaactt
    35101 caaggtattt agcatcaaaa cttcccatga aggcagttgg gtattcaacc aaattcaaga
    35161 cttcattcag caaatccgca tcaatttcga tacgtacacc atgttttgcc tcaatttcct
    35221 tgatttggtc aacaatcatt tgctcacgtt cacatggatc tgcgattaca aactgcttac
    35281 gaaggtcttc ttcatagctc aatgctgact gaattttggt ttctttcccc aagaaacgat
    35341 ggccacggct cacacgactt cccttgatat caaggaaatc caagtcaaac tcttgctcat
    35401 ccaagagaac agttaaagtg tgaacagggc ggatgtattc aaagctattt ccagcccagt
    35461 gcatgctgac agggaaagtc aatgacttca agacatctac aacaccagga acaatggctt
    35521 caactgattg gccaacttct tccttagtga catagacata ttcttcaccc ttaatttcac
    35581 ggaattcgat atcttcaaca gtcaaacctt tcccacggac aaatccttga gctgctttag
    35641 tgaagtttcc atcactatcc aaggcaattt tctttgctgg tcccttgaaa tcttctgtca
    35701 aatcagactg tttgtctgat aaaccagtca cacgaacagc caaacgacgt ggtgttgaga
    35761 aggtttgaat ggcttcaaaa gacaggcggt tttccttgag gaaggctgcc attttttcgc
    35821 ctagttgttt ttcacttggt gtgacaacat aggctggtaa ttcttcaaga ccgagttcta
    35881 ctaataagtt ttttgtcatg ttttttctcc gaaaagtatc tttttatttt ccagtttgcc
    35941 ttatgtgatt ggcacgcaag caaccaactt cgttgtttca ttgctaaaat tggagccaaa
    36001 agtctccaat tttgcctagt atccttagtt tcactaagga taccttcatc actgcggcaa
    36061 ctggctcagg gctcactctg ttcgcccatt ttcgtaattt gtcactctct ttattctgcg
    36121 tcttctgcta ggagtttagc tcttgtttct tcatccaaaa gtgggtagcc taggcgtttg
    36181 cgttctgcga caaaggtttt ggctacgaca cgggccaagt tacggatacg agcgatatag
    36241 cctgcacgct ctgttacaga tacggcacca cgcgcgtcaa gcagattaaa ggtatgtgaa
    36301 catttgagaa catagtcata ggcagggtgt accaagcctt cttctaatgc acgaccagct
    36361 tctttttcaa acttatcaaa gttttcaagc aacatttctt ggtccgaaat ttcaaatgaa
    36421 tattttgagt gctcatactc aggctggata aagatttctc cgtattttac accatcagcc
    36481 cactcgatat catagacaga gtctacttct tgaatgtaag aagccaagcg ctccaaacca
    36541 taggtaactt ccgcagtcac agggccagtt gccaatccac cgacttgttg gaaataagtg
    36601 aactgagtga tttccattcc gtcaagccaa acttcccaac caagaccagc tgaaccagtt
    36661 gatgggtttt cccagttgtc ctcaacaaaa cgaatatcgt gctccaaagg attgattccc
    36721 aatttttcca aagattcaag gtaaagttct tggatatttg atggagaagg cttcatgacc
    36781 acctggaatt ggtggtgttg gtagagacgg ttagggtttt ccccataacg accgtcagca
    36841 ggacgacgtg atggctctac ataagctgca ttccatggct caggtccgat agcacgaagg
    36901 aaagtgtaag gactcattgt tcccgcacct ttttcattat cataagcctg cataagcata
    36961 caaccttggt cattccaaaa ttgttgcaaa gtaaggatga tttcctggaa agtcaatttc
    37021 ttagacattg tttactcctt tagtttttat atttcttttt caattaattt ctgctgaaca
    37081 aaccaatcta acaagggaaa agttttttct gtatttgccc ataaatgata agaatctaag
    37141 accgcttgta cactacctaa attttctacc aacttatcta ctgtcaaaaa gctgcgccag
    37201 tattcataaa aaatacttgc atagttctta tcataagtcg aagaaccaaa atcattcaat
    37261 gaatgccaac catacttctt ctgaaaaagt tctacgagag attgattaca aattttttcc
    37321 gcttgaaatt cctcttctgt caagaaatac ttgcgactaa tatattcaac catcccctct
    37381 tcgaaccaga tataagagtc ataaccatca aaatcatcta aaaaatgctc cgaccaatga
    37441 gctaactcat gtcctacaat ctgtaagagg aaattttcag ataaagaatg atagtgactt
    37501 tctattgctt gagtttgctg agaacactcg tagtccatca attgatacaa atacaactct
    37561 ttccaaacag ctaaatcagg cgccataacc attcgtctat tatttgtata ggctggaaca
    37621 gcgctttccc taataatctg tgtagcagca ttaaaatctg accaaataac ggcttgcggt
    37681 aaatcacaga ctgcaagttc attctttaaa aaagattgat aatctttcaa cttttcagta
    37741 tttcttacta caaaatcacg aaatgtagct agttgactat cgtcttttac aagataaagg
    37801 ttgtccacgg ctctcctttc tttcacacaa tagactgaat aagcaaaaga accacatctg
    37861 acaatcctag gttgatttaa cctaggggcg tcagaaacgc ggttccaccc taatttatta
    37921 cttcattgtt tttgaaaata ctacagaaag cgccagccct ttattttgcc ctacttggct
    37981 cccactatcc caagctcgct tgaagaacgc cataagactt tctttcctgc tgactattat
    38041 atcaaaaatt agaataatgt acaattcttt ttatgatttt ctagaaatcc acatcatcaa
    38101 ctcgtggagc acccgattga acagcaatcg tttttaaggt ttctctctcc tcatgactca
    38161 gttcaattcc aaagcaatca agattagctt gaatacgaga ggttgtgaca gattttggaa
    38221 gtggtaaaaa tccttctgcc aagctccagg ccaaggctat ctgagcaacc gattttccgt
    38281 gatttgctgc tatttcttgg acttgcttgc tatcaaacag ttctccttgt ccaaaaggcc
    38341 cccaagcttc caataaaatt cccttttcac gacagtaagc tacgacttcc tcttgataca
    38401 cacctggcgc caagcgaact tgattgaccg caggaacgat agttgcagtt tcaagcaagg
    38461 catccaaatg atggggaaga aaattgctaa cgccgatagc acggattttc ccttcttgat
    38521 agaggtcttc catcgctctc caaacttccg cattgcgagt tttccatgcg tcattttctc
    38581 tgagcggttt tgggttcggc caatgaatca aatacaaatc caaataatcc aagcccagtt
    38641 tttctataga tttttccaaa gcttgacgag tttgctcata ggtttgctga ctattccaaa
    38701 gcttggtagt tacgaacatt tcttcacgtg gaactccgct atctttgatt gcttgaccaa
    38761 cactttcttc attctgataa atcgccgccg tatcaatatg acgataacca gccttcaagg
    38821 cttctaacac tgcatgatag gcttcttctc catccttagc cttaaaagtt ccaaatccca
    38881 atactggaat ttctactcca ttatttaatt gataggtatt catatgcttc tccttctatt
    38941 ttattcatca attatagcat aaaacatttt ttaagtagta ctatcttctg taaaaaataa
    39001 gtctgtcaaa tatctaacag acctattttt tcttgcttat tcatcacgac tatagtacag
    39061 ctcatgagct tttaggcgag tattgagcat ctctggtatg gtcacaaagg tataaccttg
    39121 atttttcaaa tactcaatga cccttggcaa ggcattgact gtcggactgt gaatatcatg
    39181 catcaaaacg atagagccgt tagctacttg atgctgaatt tctgtcaaaa tagatgcttc
    39241 atttttactc ttccagtcca gactatccac atcccacatg ataaagctca aatccaagct
    39301 attgcgaata tcatctgtaa tagcaccata aggtggacgc atgagtttag aactagaacc
    39361 cagcacttta gttagcacat cctcagtatc agtaatctgc tttttagctt catcaagaga
    39421 gagttgcgag agaatcggat ggctccaact atggtttcca acaacatgac cttcagattt
    39481 tatcctcttc accaagtcct cattcccaga aacatttttc ccaagcacaa agaaagtcgc
    39541 tttaatatca tatttagcta gggtctctaa tacctgcggg gtcgttgctg gatttggacc
    39601 atcatcaaag gttagagcga caactttttg atatttctta tcaaagtaag attggtacaa
    39661 ggccgcatct ttttcgagta agtacgaaga ttggataaca tcaaagaaag cagatactgg
    39721 caaggctatc tcttctaaat tttcaaccac aggacttgga taaaggataa tctgactatc
    39781 cttgtaatca aaattccatg cagacaagtc ttggtcagag aagtttttta caatctgctc
    39841 actctggtct tgctctattt ttttatcctc tatgaaggag gtcaactctt ttatcagctg
    39901 ttccttagcc ttactagcat ctgaaaacag ttggtcaagt gtaaaaggtt gcccatcttc
    39961 tgttaagtga acctttccta gactggtctt ttcagtctct tcaaccttaa aagcaactaa
    40021 atcatagatt tgtttggtca cattacgatt aacgactccc tttaaacctg actcttcttg
    40081 ctctgtatag tagaaaacaa gattgtcctt actttctagc ttgtccttaa catcttgatt
    40141 tatcaactcc ctaacagagg aaatcacttt ctccccttgg agaggataat aggcaatcac
    40201 ttcggcttgc ccctgacgaa aatgctcctt ctgatttccc tcactcaatt gatcatcttt
    40261 ctcttttttg agcgattcaa tcttttgctc aaaacttttt tgctggtaga tcttaaaagc
    40321 aataaatccg cctaataggc aaatagaaat tgctaaaata ccaatcaaag ccaataatac
    40381 atgtctcgtt ttcccgtgtc tgccacgtcc cagtctactt ttatccatat ttatatcata
    40441 acaaatttga gcaataattt caatgataca atttggcaat ccacaattcc tctagcaagc
    40501 caaagcatct tacatcaact ccaacatccg tatctgtaga gattatgtag ttttctatct
    40561 atggaatttc tagtagattg aagctagaat agtagaccta tacttctaaa acattgttag
    40621 aaatcgattt tactgtcctg atcgatttgt cctattctca tttcatttta ctataaaact
    40681 atgaaaagct aggtcatctg agaagtaatt actatcgaca attgcgatag cgtatactgg
    40741 tgcgatttgt ttgtagctct ggtgggtatc accttcacgt tggcgaattt tttctaggtt
    40801 ttgattaacc tgactgcaca gataagccca taggcgattg atgaaaaaat tctgatgatg
    40861 aatctgaatt tcgatgataa cttggattcc attatctaac tccgccaaga cgtctatact
    40921 agtatagaaa tcctgcactg agtagggcat ggaaggcaag acgtgaatgt tacttccctc
    40981 caaaatcgtc acattttttg ctggcaagtc cagcatatcg cggataaatt gacaaatcat
    41041 tagtttggct gatacccgga tgtctgagaa tcctcctttt cctccttcta ttatagcaca
    41101 tttttaaatc taggtttgct agattctatg cttctatcta tttattcgga aaagaaagct
    41161 tttcttcaga agaaagctaa tagcttattt gaaattttct cctctctgtt ggatagtccc
    41221 gtctatctat gttataatga aagaaggatt taaaatcgga aaaggagtat ttatgctaaa
    41281 attaggtatc atcggaactg gcgctatcag ccatcatttc atagaagcag cccataccag
    41341 tggagaatac caactggtcg caatctattc tagaaaacta gaaactgcag caacctttgc
    41401 ttctcgctat caaaatatcc aactattcga tcaattagaa gtcttcttca aatcttcttt
    41461 tgatttagtc tatatcgcca gtccaaactc cttacatttt gctcaggcaa aagctgcctt
    41521 gtctgctggt aaacatgtta ttctcgaaaa gccagctgtc actcaaccac aagaatggtt
    41581 tgatttgatt caaacagctg aaaaaaataa ctgttttatc tttgaagcag ctcgtaatta
    41641 ccacgagaaa gcctttacta ctatcaaaaa ctttttagca gataagcaag tgttaggagc
    41701 agatttcaac tatgccaaat actcttccaa gatgcctgac ttgttgactg gacaaacacc
    41761 aaatgtcttt tcagaccgtt ttgctggtgg agccctcatg gatttgggga tttatcccct
    41821 ctatgctgct gttcgtcttt ttggaaaagc caatgacgcg acttaccatg ctcaacagct
    41881 tgacaatagc attgacctaa atggagatgg tatcctcttc tacccagact atcaagttca
    41941 catcaaggct ggaaaaaaca tcacttccaa tcttccttgc gagatttata caacagatgg
    42001 aaccttgact ctcaacacga ttgagcatat tcgctcagct atttttaccg accaccaagg
    42061 aaatcaagtc cagcttccta tccaacaggc tcctcatacg atgactgagg aagtcgctgc
    42121 atttgcacac atgatccagc aaccagatct gaatctctac caaacttggc tgtatgatgc
    42181 aggctctgtt catgagctac tatataccat gcgccagact gctggcatta gatttgaggc
    42241 agaaaaatga aaaccaaact accgactgaa tggcaagaac tgagtgacca actcggtttc
    42301 caagaattca cccccattca aactcaacta tttgagcccc ttcttgctgg agaaaacctc
    42361 ctaggagtga gccaaaccgg aactggtaag accctagcgt atctcctacc aagtcttctc
    42421 agactacaaa agaaaaaagc ccaacaactc ttgattctag caccaaatac ggaacttgct
    42481 ggacagattt ttgatgtatg taaaacgtgg gcagaagcta tcggattgac tgctcaactc
    42541 ttcctttcag gttcaagtca gaaacgacaa attgaacgtc ttaaaaaggg gccagaaatt
    42601 ctgattggaa ctcctggccg tatctttgaa ctcattaaac ttaaaaaaat caagatgatg
    42661 aatgtggaaa ccatcatcct ggatgaattt gaccaattac tagatgattc tcagattcac
    42721 tttgtagaaa aaatcactca ctacgcacct cgtgaccacc aactggtcta catgagtgcc
    42781 acgaccaagt ttgaccaaga aaagattgtg ccgaatacac gcactattga tctctctgat
    42841 caaaaattgg acaatatcca gcatttctac atgcaggtag accaacgtca tcgagtggat
    42901 atgctacgaa aactggctca tgtagaggat ttccgtggtc tagtcttctt caatagcctg
    42961 tcagaccttg ggaatgccga ggaaaaacta cagtatcgtg atatattggc tgtttccctc
    43021 actagtgatg ttaatgttaa atttagaaaa atcatcttag aaaagtttaa agataaccaa
    43081 ctaaccctgc ttcttgcaac tgaccttttg gctcgtggaa ttgatatcga tagcctagaa
    43141 tgtgtcgtaa actttgatat tcctagagat agcgaaacct acacacaccg tgctggccgt
    43201 actggtcgta tgggcaagga aggttatgtt atcactctcg tcactcatcc agaagaaatc
    43261 aaaaaactta aaaagtttgc aagtatccga gaaattgtcc taaaaaacca agaactctat
    43321 atcaaataaa gccccattgc tctatacaca tccagtgtat ggagcttttt tataagcaat
    43381 tcaattttat actcatctgc tttcaaaaag cattctagtc catct
//
LOCUS       DBERPV010000015        42175 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.15, whole genome shotgun sequence.
ACCESSION   DBERPV010000015 DBERPV010000000
VERSION     DBERPV010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 42175)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42175)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42175
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.15"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..1954)
                     /gene="ftsH"
                     /locus_tag="ACL8C7_001056"
     CDS             complement(<1..1954)
                     /gene="ftsH"
                     /locus_tag="ACL8C7_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HGS1395274.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDE"
     gene            complement(1970..2512)
                     /gene="hpt"
                     /locus_tag="ACL8C7_001057"
     CDS             complement(1970..2512)
                     /gene="hpt"
                     /locus_tag="ACL8C7_001057"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HGS1395275.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2516..3793)
                     /gene="tilS"
                     /locus_tag="ACL8C7_001058"
     CDS             complement(2516..3793)
                     /gene="tilS"
                     /locus_tag="ACL8C7_001058"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HGS1395276.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRTKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3790..5058)
                     /locus_tag="ACL8C7_001059"
     CDS             complement(3790..5058)
                     /locus_tag="ACL8C7_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HGS1395277.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGELTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5051..5173)
                     /locus_tag="ACL8C7_001060"
     CDS             complement(5051..5173)
                     /locus_tag="ACL8C7_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0009 family protein"
                     /protein_id="HGS1395278.1"
                     /translation="MENLLDVIEQFLGLSDEKLEELADKNQLLRLQEEKERKNA"
     gene            complement(5178..5546)
                     /locus_tag="ACL8C7_001061"
     CDS             complement(5178..5546)
                     /locus_tag="ACL8C7_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HGS1395279.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5539..5805)
                     /locus_tag="ACL8C7_001062"
     CDS             complement(5539..5805)
                     /locus_tag="ACL8C7_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HGS1395280.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(5863..9372)
                     /gene="mfd"
                     /locus_tag="ACL8C7_001063"
     CDS             complement(5863..9372)
                     /gene="mfd"
                     /locus_tag="ACL8C7_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HGS1395281.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLMSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKELMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            complement(9373..9942)
                     /gene="pth"
                     /locus_tag="ACL8C7_001064"
     CDS             complement(9373..9942)
                     /gene="pth"
                     /locus_tag="ACL8C7_001064"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HGS1395282.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDEYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10013..11128)
                     /gene="ychF"
                     /locus_tag="ACL8C7_001065"
     CDS             complement(10013..11128)
                     /gene="ychF"
                     /locus_tag="ACL8C7_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HGS1395283.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11212..11406)
                     /locus_tag="ACL8C7_001066"
     CDS             complement(11212..11406)
                     /locus_tag="ACL8C7_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HGS1395284.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(11471..12607)
                     /gene="dnaN"
                     /locus_tag="ACL8C7_001067"
     CDS             complement(11471..12607)
                     /gene="dnaN"
                     /locus_tag="ACL8C7_001067"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HGS1395285.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(12766..14127)
                     /gene="dnaA"
                     /locus_tag="ACL8C7_001068"
     CDS             complement(12766..14127)
                     /gene="dnaA"
                     /locus_tag="ACL8C7_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HGS1395286.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14340..15098)
                     /locus_tag="ACL8C7_001069"
     CDS             complement(14340..15098)
                     /locus_tag="ACL8C7_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HGS1395287.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLETLLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15156..16337)
                     /locus_tag="ACL8C7_001070"
     CDS             complement(15156..16337)
                     /locus_tag="ACL8C7_001070"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1C family serine protease"
                     /protein_id="HGS1395288.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLRSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16520..16999
                     /gene="rlmH"
                     /locus_tag="ACL8C7_001071"
     CDS             16520..16999
                     /gene="rlmH"
                     /locus_tag="ACL8C7_001071"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HGS1395289.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17043..17116
                     /locus_tag="ACL8C7_001072"
     tRNA            17043..17116
                     /locus_tag="ACL8C7_001072"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17077..17079,aa:Arg,seq:tct)
     gene            17317..17406
                     /gene="comC"
                     /locus_tag="ACL8C7_001073"
     CDS             17317..17406
                     /gene="comC"
                     /locus_tag="ACL8C7_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HGS1395290.1"
                     /translation="MKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            17427..18752
                     /gene="comD"
                     /locus_tag="ACL8C7_001074"
     CDS             17427..18752
                     /gene="comD"
                     /locus_tag="ACL8C7_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence system sensor histidine kinase ComD"
                     /protein_id="HGS1395291.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            18749..19501
                     /gene="comE"
                     /locus_tag="ACL8C7_001075"
     CDS             18749..19501
                     /gene="comE"
                     /locus_tag="ACL8C7_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence system response regulator
                     transcription factor ComE"
                     /protein_id="HGS1395292.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19553..19624
                     /locus_tag="ACL8C7_001076"
     tRNA            19553..19624
                     /locus_tag="ACL8C7_001076"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19586..19588,aa:Glu,seq:ttc)
     gene            19630..19703
                     /locus_tag="ACL8C7_001077"
     tRNA            19630..19703
                     /locus_tag="ACL8C7_001077"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19664..19666,aa:Asn,seq:gtt)
     gene            complement(19744..20286)
                     /locus_tag="ACL8C7_001078"
     CDS             complement(19744..20286)
                     /locus_tag="ACL8C7_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGS1395293.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20414..22067
                     /locus_tag="ACL8C7_001079"
                     /pseudo
     CDS             20414..22067
                     /locus_tag="ACL8C7_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
     gene            complement(22097..24649)
                     /locus_tag="ACL8C7_001080"
     CDS             complement(22097..24649)
                     /locus_tag="ACL8C7_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HGS1395294.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     GAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFMTGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(24711..26333)
                     /locus_tag="ACL8C7_001081"
     CDS             complement(24711..26333)
                     /locus_tag="ACL8C7_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS1395295.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            26539..27564
                     /gene="trpS"
                     /locus_tag="ACL8C7_001082"
     CDS             26539..27564
                     /gene="trpS"
                     /locus_tag="ACL8C7_001082"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HGS1395296.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            27716..29194
                     /gene="guaB"
                     /locus_tag="ACL8C7_001083"
     CDS             27716..29194
                     /gene="guaB"
                     /locus_tag="ACL8C7_001083"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HGS1395297.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(29245..30342)
                     /gene="recF"
                     /locus_tag="ACL8C7_001084"
     CDS             complement(29245..30342)
                     /gene="recF"
                     /locus_tag="ACL8C7_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HGS1395298.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKVAVNGN"
     gene            complement(30345..30713)
                     /gene="yaaA"
                     /locus_tag="ACL8C7_001085"
     CDS             complement(30345..30713)
                     /gene="yaaA"
                     /locus_tag="ACL8C7_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HGS1395299.1"
                     /translation="MEYKLFEEFITLQALFKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            30872..32122
                     /locus_tag="ACL8C7_001086"
     CDS             30872..32122
                     /locus_tag="ACL8C7_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGS1395300.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQSYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            32119..33402
                     /locus_tag="ACL8C7_001087"
     CDS             32119..33402
                     /locus_tag="ACL8C7_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGS1395301.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSIDTLVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            33444..34265
                     /gene="rodZ"
                     /locus_tag="ACL8C7_001088"
     CDS             33444..34265
                     /gene="rodZ"
                     /locus_tag="ACL8C7_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoskeleton protein RodZ"
                     /protein_id="HGS1395302.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            34276..34821
                     /gene="pgsA"
                     /locus_tag="ACL8C7_001089"
     CDS             34276..34821
                     /gene="pgsA"
                     /locus_tag="ACL8C7_001089"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HGS1395303.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            34818..35645
                     /locus_tag="ACL8C7_001090"
     CDS             34818..35645
                     /locus_tag="ACL8C7_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HGS1395304.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            35630..36469
                     /locus_tag="ACL8C7_001091"
     CDS             35630..36469
                     /locus_tag="ACL8C7_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HGS1395305.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEKVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            36462..37256
                     /locus_tag="ACL8C7_001092"
     CDS             36462..37256
                     /locus_tag="ACL8C7_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGS1395306.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            37315..38133
                     /gene="mreC"
                     /locus_tag="ACL8C7_001093"
     CDS             37315..38133
                     /gene="mreC"
                     /locus_tag="ACL8C7_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HGS1395307.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            38133..38627
                     /gene="mreD"
                     /locus_tag="ACL8C7_001094"
     CDS             38133..38627
                     /gene="mreD"
                     /locus_tag="ACL8C7_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HGS1395308.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFAIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            38721..39899
                     /gene="pcsB"
                     /locus_tag="ACL8C7_001095"
     CDS             38721..39899
                     /gene="pcsB"
                     /locus_tag="ACL8C7_001095"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan hydrolase PcsB"
                     /protein_id="HGS1395309.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            40123..40902
                     /gene="rpsB"
                     /locus_tag="ACL8C7_001096"
     CDS             40123..40902
                     /gene="rpsB"
                     /locus_tag="ACL8C7_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HGS1395310.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            40981..42021
                     /gene="tsf"
                     /locus_tag="ACL8C7_001097"
     CDS             40981..42021
                     /gene="tsf"
                     /locus_tag="ACL8C7_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HGS1395311.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
BASE COUNT        13224 a         7268 c         7773 g        13910 t
ORIGIN      
        1 tttcgtcatt catttttgac tttacttcat cataggatag tgcatgagat tcctcttcta
       61 ctgcttcagg catctttcct gtttcgtaaa gagctttaat ttgtgtacta tccaatgttt
      121 cgtatttcaa taatgcttct gcaattaact tgtgagtttc acgatttgac tgaataattt
      181 cagcagcttt atttcgtgcc tcatttaata atgaacgaac ctcttcatca atttcataag
      241 ctgtttgttc tgaaattgat ttttgaggac tctgtgcacc aagcatagca tggtttcctt
      301 catattgtac tgggccaagt ttttcactca taccgtactc tgtaaccatt gcacgtgcca
      361 tttgtgtcgc ttgttcaaag tcgtttgaag ctcctgtagt ttggacatta aagataattt
      421 cttcagctac acgtccaccc attaagccag ccaattgctc tttcatatct tctttagata
      481 gaagcatttg atcctcttta ggaagtgcaa tcatgtatcc gcctgcacgg ccgcgtggta
      541 caattgtaac cttatggaca acgcgagcat tcgacaagac tagaccaaca atggtatgtc
      601 ctgcctcatg gtaagcaacc aattctcgtt ctttttgtga aactgtctta tctttcttag
      661 aaggtccagc aataactcta tcttctgctt catcaatatc tgaagcatca attatcgatt
      721 tattgcgacg agcagcaact aaagctgctt cattcaagac attctctaaa tcagcaccaa
      781 caaagcctgg agtttgttga gccactaatt tcaaatcaac atcttctgct aaaggcttgt
      841 tcttagcgtg aactttcaag attgcttcac gacctttaac atcaggacgg ccaaccaata
      901 cttttctatc aaaacgtcct ggacgcaaaa gggcaggatc aagtacatct gaacggtttg
      961 tcgcagcgat gacgataatc ccttcatttc cctcaaaacc atccatctca atcaaaagtt
     1021 ggttcaaggt ttgttcacgt tcgtcattac ctccgccgag accgactcca cgttgacgtc
     1081 caacagcatc aatttcatcg ataaagatga tagctggtgc tgcttttttg gcatcctcaa
     1141 aaagagagcg aacacgacta gctccaactc cgacaaacat ttctacaaag tcagaacctg
     1201 agatactaaa gaatggaaca cctgcttctc cagcgactgc cttagcaagc aaagtcttac
     1261 ctgtccccgg aggtccctcc aaaagaacac ctgctggaat acgggctcca agttttgtga
     1321 atcgttttgg atcttttaag aactcaacaa cttcaactag ttcttgtttt tcttcctcag
     1381 ctccagcaac atctgaaaat cttactttaa tatcttcttt atttgctgct ttagccttac
     1441 tacgtccaaa actcattgga ttacggccat tgcctcctcc catatttccc atcatagaga
     1501 ataggaagaa gaatagaatt ccaaatggca caatggatac gagtagatta atccatatac
     1561 cacttgaact ttcatgctta acagttactt ctgctttatg gtcagtagca agtttttgca
     1621 attctgatac ggtagtatct gcaggaagaa tagtgctggt aaatttctct accttagtaa
     1681 cagatggcgt gaaaaactga atacctgttc cttctttact tgttttagga tttttataga
     1741 caccagaaac ttcgataaca ctaccatttg gttggtaagt taattctttt acattaccat
     1801 cggtaatttc ttgtaccaac tcagtatagt tgatttgctg acttcctcct gagttattcc
     1861 cagaatagaa atactggaat cctgtcacaa ggaaaaagat aaataataac catagaaaag
     1921 gatttttaat taaaccatta ttttgttttt tcattaaaga ttattctttc taatttgaat
     1981 acacttcctc tttcaatact ccaatataag gaagattacg ataattttct ttgtagtcta
     2041 aaccataacc tactacaaac tcatttggga tagtaaagca ggtatagtct gcctcaattt
     2101 ctacaacacg tccttctggt ttatccaaca aggttgcaat tttaacagaa gctgcttctc
     2161 tttctttaaa catatctcgc aaattcttca aagtttgacc tgtatcaatg atatcttcta
     2221 caaatagaac atgtcttcct ttgatatctt gagtcacatc ttgtttaata ttgataacac
     2281 cactacttgc tgttccacca tggtagctag aaaccatcat gaagtccatt tcaatatgtg
     2341 tatcaatatg tttgaccaat tcagccataa aaggaataga tccttttaaa atcccaacta
     2401 agattggatt ttttcctgca taatctttag ttaattgagc acctagtttt ttagctgctt
     2461 ctgtaatttc atcgtgtgaa acgaggactt ttttaatatc gttttctaac attttttacc
     2521 tatctatttt ttctatataa agtacagtgt tcattatatc atttttcgtt tttttactca
     2581 aattattggt cgcaattccc aaaattgaga caatttcacc aaattgctca ataataagag
     2641 cagagtttct cttttccata gggattttca aatcaataaa taaacgtctg agttttgttc
     2701 tatgcccatt ttgaatcaaa acatctcctg tttttcgatg acgaatgtgt atggatgttt
     2761 cacgtgaaac aggtatttgt tgaattgatt caccttctaa tggaagtcca aaggaaaata
     2821 aatatccttg ataagctacc tgattttgat agtgtaacac aagttcatct tccttttcat
     2881 cagcctgcgg actgatttta caaatctgaa actgttggta ctcttttatc aattcatagc
     2941 catttttaat cggatgacga tactggcttt tagattttaa aatctgctga acttcagcaa
     3001 actgagcttt tgtaagattc aaatctggaa aacgattcag ataagtttga agtaaaactc
     3061 tttgtgtaga ctcagagtaa gaaaataact gctgtaaatc ttccacatta atattgttag
     3121 ataattcagc tattgccaaa tcataatcta aaatttcatt gccaatgcct aagattgcat
     3181 ccctaaatcg aggattttct ttttccaatt ctggtaagta agagtttcga atacgatttc
     3241 gaaaataatg attctcctga tttgatgtat cttcaaagtg aaaaattgat ggaaagtctt
     3301 ttttctgaaa atgcaagaag ggacgaatga tttctatctc tccgactact tgcttctcct
     3361 taattcctga tagatagcgc aagcgagttc ctcgaatcaa gcgcatcaaa atcgtttcca
     3421 cctgatcatc agcatggtgg gcagtgacta aagctgtcgc acctgtcttt ttcataacct
     3481 cttgaaaaaa atcataacga aaatttcgtg cacgcgcttc tgaaaattct cctgaaaaat
     3541 tgctgatata aataggaagc tctgcttcag cagccaactt ccttaattcc ttttcttccc
     3601 aatctgattc aattctctgc ttatgattca catgagccag aatcaattca atctctaact
     3661 ctttttgata agtagacaat accttaaata gaaacataga atctaatcca ccagaaagag
     3721 ctagaaccgc cttagcatgc tttttgaaat atcccttctt gagaaaatga tttaaaaaat
     3781 ctggttccct cattttaaaa cctcataaac atccttggct atcttagaaa tcgtatcata
     3841 atcagaattc ttagtgaaaa tagaaagaat aaatggagaa tctgcataga caacacccgt
     3901 atcatgctta aattcatccg catctccaat tttatgagct actttaacag aaacaccttt
     3961 ggcaattcgc tgactatcaa aatctgtttt agtcaaagac tctagcacaa atccattttg
     4021 attataaata gcttccataa acttcccggc catcttagaa gaaatcaatt tttcttttgg
     4081 atcccaatca tctcccataa tggcagacat tttggatttg aatgtggcat cagattggtt
     4141 tgaaatgtaa tatcccaata gattatgagc tacattatca gattcttttg atactttcgt
     4201 aattaaatcc tttaaagaat attctttatt atcttctttt ttaggaagac taccacttcc
     4261 ctctggttta taagaacctg gaaaatcatt gactgcagat acgtatttta cagtcgtatc
     4321 taactgataa agaccctcat ttattttttc ttgcgtataa tagagatagg agagtttcaa
     4381 aacgctggct gcatacatct tttcatcttg attgatacca gcttcttttc cagtagtcag
     4441 ttgcttaaca taaatagaga aagaatcttt ctgatatttt tcagataaca tttcttgaac
     4501 tttactcatc cgattatctt cttcagaagt tgattcttta gctacccatc cagcctgatc
     4561 aatatgtaga aattctcttc cttctacaaa catggtcttg tcgattgata cttgcgaata
     4621 agctgataag gatgatttca cttcttttaa atcataagga ctattgtaca gtttaaagtc
     4681 agattctaac catacttttt ttattgttgg agttacctct gattgatcat ataaaaatcg
     4741 tttgtccgca gctataaatt gatgatttga tagcttaaat actggaatcc cttgtttatt
     4801 taagcgccac tcggttattt gaaaacttgt tttgggagtc aattccccag attccactac
     4861 taaatcttca ttcgcataaa caggaacctc tccataaacc atgggagaac ttaatttttc
     4921 tctaaaataa ataccaaagt cagattgtga aaggtaataa atttctttcg aagtatagac
     4981 gacttctttt tctgtgctaa cgacttttga aatggtcaaa aaacttggta gcaacaaaat
     5041 aattaagaat ttacgcattc ttcctttcct tttcttcttg taaacgcaat aattgatttt
     5101 tatcagccaa ttcttccaac ttttcatctg acaaacccaa aaattgctct attacgtcta
     5161 ataaattttc cattttatca cctttgaagc aagtcaggaa tcgtataaac tttttccctc
     5221 gacttagaat aatagtactt cgctcgtgta tatttagcag cataatcttc atctttcaac
     5281 ttggtagcaa atgctgtctc cttatccttt tcatcactca aagtttgata ctgagtttgc
     5341 aagtctgcta attgctgacg tctttggagt aattgctgat aactctgcgc taaattaaaa
     5401 gttggcaaga taaataatag cataatcaaa atcaataccc ctcccataaa acgattccgt
     5461 ttttgtcgtt ctttcatcag gtagcgacga cgttggtatt cattttgaat aaaagaatta
     5521 ttcaattgta caatattttt agacattttc ttctacccgt gtttcactga taatttcata
     5581 cattcctgct gcatcttctt tttttgtact atctttcatc tctagtactt ttacaagcag
     5641 caacttattg ccaaagcgaa tttcaacttg gtcattaact ttcaagtccg ttgaactttt
     5701 ggccaagatt ccattaacct tgattctacc tttatctgct acttcctttg cgactgtacg
     5761 acgcttgata attcgcgata cttttaaata tttatctaat ctcatcctta ttacctcaat
     5821 ttattattgt accattttta tctattttat agaagaaaaa tatcaaatgg aattttcttc
     5881 cttagactct tttatctcta ataaactttc tccaaaaatc agcagacctt ctaaaatttc
     5941 ataatctttc ttattttgaa catcaaatac aagctccatt aattccttat tctcagcgat
     6001 gcctgctttt aagttcgtta cggataaagc tttaaaataa tcttgagcta aaaacagtcg
     6061 ttgagtgact ttttcaaatt gaattgtaat tttattatct tttctttcca cacgttgaac
     6121 aaagaccttg tccaagtatg atttgaccaa accaatctct aaaagatagg ctactacatc
     6181 tgggtattct ccaaaacggt ctatcaactc ctcttgtaac tcttcataat tgacacggtt
     6241 gtcaatttga cgaattttct tgtaaatttc aatcttatgt cgttgatcag aaatataagt
     6301 atcaggaaga taggcatcaa tttgcaaaat caactcagca ttccctttgg ttcttgtgtt
     6361 agcgttagca ttaccgtttc gtttagcaat agcttcctct aataactgcg aatacaattc
     6421 aaaaccaaca gaatcaatga aaccagactg ggattttcct aaaagatttc ctgctccacg
     6481 aatcgaaaga tctcgcattg caatcttaaa gccagagccc aattctgtaa atcctttaat
     6541 cgcttctaat ctcttttcag agacttcact gattgatttt tctggacgat acatgagata
     6601 agcataagca atacgattac tacgaccgac tcttcctctt aactgatata aggttgacaa
     6661 gcccatatgg tccgcatttt caataaataa agtattagca tttggaatgt ccacccctgt
     6721 ctcaataata gtagtcgtca ccaagatatc gtattgtccc tcaataaagt ctaatagagt
     6781 attttccaac tggacttcac tcattcgacc atgaacatat ccaatcgaag cctccggaat
     6841 caactcctgt aattctgaaa ccttctgaac aattgtgtca actttgttgt aaagataata
     6901 aacttgacct ccacgctcca tttcacgcaa gacagcatca cgaatgacac tatcattctt
     6961 ttccaaaaca taggtctgaa caggatagcg attagtcggc ggagtttcaa taacagataa
     7021 atctctgatt cccagcatag acatatggag ggtacgaggg attggcgtag cggtcaaggt
     7081 taggacatcc acttgtttct tcagttcttt caaagtttcc ttatgcttga caccaaatcg
     7141 ctgttcctca tcaataatca tcaagcccaa atcagcaaac acaacatctt ttgacaaaac
     7201 acgatgtgtt ccaatcaaaa tatcgacttg accgtttttc aatttttcaa gtgttgcagt
     7261 ctgctctttt ttacttctaa agcgactcaa cacatcaata ttaactgcaa aattttggaa
     7321 tcgttcctta aaattcgtat agtgctgttg cgctaaaacc gtcgtcggaa ctagaatgac
     7381 aacctgtttg tgatcattga ctgctttaaa ggctgcacgc atagcaactt cagtctttcc
     7441 aaaaccaaca tccccaacta aaagtcgatc cattggctga gaagcctgca tatccctctt
     7501 gatttcctca atactacgaa gttgatcatc cgtttcaaca taagggaaag catcatcaaa
     7561 ggcatcttga tcatcatcat cagctgagaa agcaaaaccc ttcaactgac tacgttcaga
     7621 gtagagtttg attaaatcat cagctatatc ctctacctgg ttcttaacct tttgcttggc
     7681 ctttttaaaa tgaccgtcat ttaatttatt gagttttgga gctttaccat cacttgaaat
     7741 atatttggac agtagatgaa tctgttccac gggaatagaa atttgatcac cattttggta
     7801 ttggacactg acataatcac gatgaattcc cttgatttca atggtttcaa ttcctagata
     7861 ttgaccaatc ccatggatat gatggacaac atagtcccct ttttcaagtt cattgtaatc
     7921 ttttaatctc tctgcatttg aaacatgttg tcttcgaaaa cgacgcttta atttcttttg
     7981 aaaaatctca tgttcagtta tcaataaaat cttttcatct acaaaatgaa aaccatgtct
     8041 gagattaccc tctattaagt ttacagattc tttacagata tttgtcttat ctctagaatc
     8101 caatttaatc tgatattcct ctaacatatc ctccaatgtt ttacttccca ttgaattgct
     8161 agactgcaga ataatggtgt aatccatttt tttatatcgt tcaatttctt cttttagaaa
     8221 agaaaactga ttgaaaaatt cctgcatagg atattgattg aattgataaa ttttgtcaaa
     8281 tttgagattt cctaaaccct tttgaagatt agaaaaaaag gtcactggac tttgtttttt
     8341 atagatttgt tcaatatcag aaaaatactg catatcagaa aatgctttac tattctgtaa
     8401 ttcttctgta aagtactgcg ctaattctct ttcaaagact tcatactgat tcatcaattt
     8461 ttgataatca tcaaagaata ttggagtatc tttttcaata taatcaaaga cagtccatgt
     8521 cttatcatag cacaaagata aaaacttccg agagtctgca tgactttgtt tttggtgaaa
     8581 acttgaaaga atttcttcta ggtatgattt caaaataggt gataaagttt ttgaaatttg
     8641 tttttctaaa gctgactgtc ctcgttgata atccttttct ctcaaaagca tatcactagc
     8701 tggaaagata gtgagttctg tcttattttc tttcgataat tgtgtttcta cttcaaatga
     8761 cctgatacca tcaatttcat caccaaaaaa ctcaattcga caaggttcta actgggatat
     8821 ttcaaaaata tctaaaatat ctcctcgaag actaaattcg ccctgagttt gtacttgagt
     8881 aacttttcga tagccatttt cctttaactg atggataaac gcgtgttgat catattcttc
     8941 accaactgag atttttacaa tactatcttt gaatgcattg ggagacggta aaatcaatcg
     9001 acttgctgcg atattacaaa ctaaaatccc tttcttagat gaatcagtca aaaaacgcaa
     9061 ggcttcaacc cgtgaaataa ttttttcctg tgaagacatc aaaaactcca ccataggagc
     9121 atcatctacc aaaaatggat agacgagttc ctcacccaag atagatataa gatcactaac
     9181 aagtccttct gcttctccat aagttgacat caataacaca atcctatctt ctttttctaa
     9241 actgcttgca attgcaagag ccttagtaga tgttgataaa ccaagtatta gttgtctttt
     9301 cttatctgtt aaattttgat gccatttttt aatctgatca ttttctgaga ataaatctaa
     9361 taaggtcacc atttatccgt tatacctctg cattgttttc tcaaaatttt tctcttgtaa
     9421 atagtagttt acagaatcgt caactttgtc aacagactgt aaaataccga tatactcatc
     9481 cctgtcaaac ttactcaaaa catgatgaac aactgacata ccatttttag gtcttccaat
     9541 tccaatctta acacggttaa agacctgagt tcctatatgt tgaataatag acttgatacc
     9601 attatgacca cctgctgagc cttttgctct taaacgaatt ttcccaactt ccatgtcaag
     9661 atcatcgtaa atgataagta aatcgtcaat atccaaacca tagtaagtta ataaagcatg
     9721 aactgctttt ccactttcat tcataaaggt cgttggttta accagataaa ttttttctcc
     9781 atttaggaaa aaggatgcta ggtcagcttg aaatatctta tcgtgtgtaa aagtgacatt
     9841 ctgtttcttc gctagttgat caatcaacat aaaaccaaca ttgtgttttg tttcaaaata
     9901 tttatcccct ggatttccca agcctacaag taatttggtc atttattttt cctttcaaaa
     9961 gccaaaaggg ttggaatttt tttccaacct aattgacacc atttattaat ttttagacat
    10021 taaagcggaa ttccatgata tcgccatctt gaacgatata ttcttttcct tcttcacgca
    10081 agcgtccagc ttcttttacg gccttttcag atccgtattt cactagatct tcatatgaca
    10141 tggttactgc acgaataaag cctttttcaa agtctgagtg gataatacca gctgcttgag
    10201 gagccttcat accacgtttg aaagtccaag cgcgaacttc tttttcacca gctgtgaagt
    10261 aagttcccaa tccaagcaag tggtaagctg cacgcgtcaa cttatctaca cctgattctg
    10321 tcaaaccaat ggcttcaaga aactcttttt tatcttcatc atccaattca gaaatttctt
    10381 cctcagcacg cgcagaaata acgactactt cagcattttc tgtcgctgca aattcacgaa
    10441 tttgtttgac atagtcgata gagtcaggtt ctgaaaccac atcctcgtcc acattagcta
    10501 cataaagaac tggtttagtc gtcaaaagga aaagaccttt gacaaccttt tgttcctcat
    10561 ctgtaaattc aatggtacga gctgatttcc cgtcttctag gactggttta atcttttgaa
    10621 gaacattgaa ttctgctact gattctttat ctttttgcgt acgtgccatc ttttctacac
    10681 gcgcatatcg tttgttcact gattctaagt cagcaagaat taattccaga ttaattgtat
    10741 caatatctgc aagtggatct acaaaggcgt cttcacgtcc ttgctcgcgc atcacatttt
    10801 catcatcaaa agcacgaact acgtgaacaa tcgcatctac ttcacgaata ttggccaaga
    10861 atttattccc tagcccttct ccttttgaag ctccttttac aatccctgca atatccgtaa
    10921 attcaaatgt tgtgggaact gtctttttag gagttatcat ttcagttagt ttttgtaggc
    10981 gttcatctgg aacttccacc attccaacat ttggatcaat agtcgcaaat gggtagtttg
    11041 ctgcctctgc tcctgctttt gtaattgcat taaatagtgt tgatttacca acgtttggca
    11101 aaccaacgat acctgctgtc aaagccatat ttctcattct ccgttttcat ttcaatccct
    11161 aatattataa cacaaaaagg gataaagtgc taaccctcta actaagggtt ctcagtcaat
    11221 aattttattc atttttcgct caaaatcata tcgccccatc atgacaacat gctcacaatt
    11281 actgcatttt attttgatat ctgctcctac acgtgtaatt tcccaacgat tagccttttt
    11341 accagtcgac ttgattgtac aagcgtgtga ttttttcatc tcaacaaaat ttccaacttg
    11401 atacatacta ctctcctttt ctttttcgat tatatcataa aagaggcgag ccaggctcaa
    11461 cctctttcac ttaatttgta cgaactggtg taatgagctg catgaagtct tcgtcagtat
    11521 ctgctggcac aagagtaaat ggacgaacag ctgagataaa gctaatggtc accttttcgc
    11581 tatttaaagc tttaagagaa tcaatcaagt aagttgggtt gaaactaatg gtcaaatctt
    11641 caccagtaac ctgatcagta tcgatttctt cgtttacttt accaacttct ggagagtgaa
    11701 catgggcgct aacaacccca tccttaattt caagtttcac agtaccattt tgagtcgcac
    11761 ttgataaaag acgggcacgc tccattgact ggcgtaagtt taccacatta aaagtaatag
    11821 tagtgttaaa gtctgttgga atcaagcgat ctgtatcagg atagtttcct tctaggagac
    11881 gagtatagaa gctaatattt tcgcttctaa agaggatttg gttattggca aagaaaatct
    11941 ctacagtttc gatatcatct gtaaataccg ctgaaaattc gcgtagagaa cggctaggaa
    12001 ttacgacatc aaaatcatca ctattttttt caagagtcaa ttttttctgg cttaggcgat
    12061 gagagtctgt tgcaactgtt tttaactctt tgtgttgact caatacgaag tggacacctg
    12121 ttaaaatcgg acgactctct tgtgtacttg cagcaaaggc tgtttcatta ataattttct
    12181 tgagtaattt tgtttcaagt attaaaggag tgcttgctga aatttcttgg attcgtggat
    12241 attgttcgct atcttttcct tttagggtaa tttctgattt gccactggtt aaaacaattt
    12301 gattttgttc aatttcttta aaatcaagag ttacatcagg taaactagat actacattga
    12361 taaagaaaga agcttcaaga aggatcgaac ctaaagaagt aattaacaaa ccagcatctt
    12421 catttttttg agaaataaaa ttttcaattg aaatttgacc atttgaacca attaaagtaa
    12481 taccttcatt ggtcacgtca atttttactg ttgataaaat aggaatggca tttttagaac
    12541 taatagctct cttagtagta tttaatgctt gtagaaataa atttttatta attgaaaaat
    12601 gaatcatgga ttctccttta tttattttta gtattagaaa gataatagta ataatagagt
    12661 ctgtgaaatc tgtggaaaac agcctttaaa caagtcatat caagtttttt agcttgttta
    12721 aaaaatgtgg ataaaaaaga taaaaaacta aaagttatcc acaaattatt tgattttctt
    12781 tttgattgat tcaatttcta aacgtaaatt atcgtcttga tcaatcaaag attttatttt
    12841 ggcatgggca tgaatgactg tggtatgatc ttttccccca aattccttcc caatttttgg
    12901 aagactatta tctgttagtt ctctagataa atacatggct acttgacggg ccaaaacaat
    12961 attttgaagg cgtctacttc ccttcatttc tttgatacta acaccataaa agttaccaac
    13021 ttcagtttgg attttatcaa ttgggatgac gagcatttgg ctaacatctt gtttgcgggc
    13081 tctaatggct tctgcagcaa tatcaatagt gatatccttg atttttttta ctctggcaat
    13141 taaagtgatg tcgttgatgg ctccctcaag atctcgaaca tttgaatcaa attgcccagc
    13201 taggtattct agagtatcac tttggaaatt gtagcctaaa tgttccgtct tactttgtaa
    13261 aatggcaata cgtgtttcaa agtcaggggg tgtgatagtt tgtgtcaatc cccaactaaa
    13321 acgcgtgaca agcctctcct cgagcccttc tagatgtttt ggactacgat cactcgttag
    13381 gacaatctgt ttttgcttgt catgaagggc gttaaaggta ttgaaaaatt cttcctgagt
    13441 tgcgactttt tttccgctga gtgactgtat atcatcgatt aacaaaagat caagactacg
    13501 ataggtcttt ttaaactttt ccatttcccc aagtcttagg tgatcaagaa agtcattaat
    13561 aaagctttcg gcagggatat atttaacacg cgcattagga atatttttta gaatttcatt
    13621 tccaatagcg tttaataagt gagtcttacc aaggcctggt cctccataga taaaaagagg
    13681 gttataggtc agagccaaat cttcagagac agctaaagcg gctgatacag cccaaacatt
    13741 tccatcccct tgaataaagt tatcaaaggt atacttttct tttaatcccg tatctgaata
    13801 aggaatagat actaactttg gactatagtc ataaagagtt aaatttgtag cttcttcaac
    13861 ttgtgagcta gtcgtatctt gaggtttggt gaaaatatag tggggagtta tttcagcgtc
    13921 ataaatttca aaaccagcta ctacaataat atcttttagt tgtttttccc agaccatttc
    13981 catttcagag cgaggtagaa atatagtggc aacattttcc tctaccttga tgagttcagc
    14041 ttgaatagca tagaaatcat acatggatcg agtcagtctt tcttgtgcaa attctaatat
    14101 acgattccaa aattgttttt ctttcaatcc tttctcctcc tttactattt aaaagtttaa
    14161 tactagagat attttaccat agatagcaag aattttccac aagctgtgaa aaataatcca
    14221 caatgttacc aaactttatc cacaggttgg ggataaaaga agaaattatt gatttattaa
    14281 gctttttatc gaaaaacata gtggataacc ttgtgagata aaaaaataaa agaacagcct
    14341 tatttcaggc tgttgataat tctactatat tcttcttgat ttgaaaaaga aataatgatt
    14401 tttccactgt cttttttaga tagtttaatt tctacatcta aaccgagtag ttttcttaac
    14461 tgtttttctt cattttgtat gaaatgatta gttttttgct gtttcttttg ttttttctct
    14521 gtcagaagag tttctaactt ccttacagaa atatcttctt ctataatccg ttgaaagaaa
    14581 tagtcttgtt gttccttatt taacccaact agggaacgcg catgggcttg tgatagtttg
    14641 ccattttcta cttctgagag aatctgttct ggcaaggaaa gtaaacgaat ggagttgctg
    14701 atatatggac gagacttgcc catcttatct gcaatttcag catgggtgaa tcctttctct
    14761 acgagagatt cataggcgcg tgcttcttct attgggttta aattttctct ctgtaaattt
    14821 tcaataatgg actggaccat catctcttgg tctgaaatct gtttaacaac agctgggata
    14881 gaccgtagac cagctaaaag tgaagcccga tagcgtctct ctcctgcaag gatttcataa
    14941 ccaataacag gagattgacg aacaataatc ggttgaatga ccccattttc tttgatagac
    15001 tgtgctagtt catctagttt ttctctatca aattcttttc ggggttgata gggatttttt
    15061 tgtatatctg tgatagaaat catttcaaat ttttccatga ttctacacta acacatcttt
    15121 tctcttatgt aaagctttct ttacatagat gtcaatcaag attctaaatc acctgaactc
    15181 ttgttaagtt tgatagaggt agtttcttct ttcccgttac gatagtaggt tatcttaatg
    15241 gtgtctccga tagaatggtt gtaaagagca ctttgtaagt ctgttgatga agcaatctct
    15301 ttgtcatcta cttttgtaat tacatcgtat ttttcaaggt gaccattggc aggcatatta
    15361 ctttgtaccg aacgaacaac tacaccagat gtaacattac ttggaatatt gagtcttctg
    15421 atgtcgcttg tactcacatt agataaatta accatctgga ttcccaaagc tggacgcgtc
    15481 acttttccgt ttttttctaa ctgttcaata atattgatag catcatttgc aggaattgcg
    15541 aaaccaagac cttctacaga tgttcctcca tttgtagcaa ttttacttga ggtaattccg
    15601 ataacctgcc cttgaatatt gatcagtggg ccgccagagt tacctgggtt aatagcagta
    15661 tcagtttgga tggcttttgt agaaatagct tgtccatctt ccgatcttaa ggatacattt
    15721 ctattgagac tggatacgat accttgagtg acagtatttg catattcaga acctaacggg
    15781 ctaccgatgg caatagcagt ttctcctaca gttaacttac tagaatcacc aaactcagct
    15841 actgttgtca ctttttctga agagattttg acgacagcaa tatcagagaa agtgtcagct
    15901 ccgacaattt ctccaggtac tttagtccca tctgacaatc gaatatctac tttgctggcg
    15961 ccatttataa cgtgattgtt ggtgacgatg taagcttctt tatcattctt tttataaata
    16021 actccagatc cttcactaga gattcgctga gaatctgtgt cagtatcatc attgccaaat
    16081 acgctatttt gtctgtttgc cgaataagta ataacagaaa caacagcatc ttttactttg
    16141 ttaacagcct gtgttgttga attttcgttc ttataggcag tttgtgtaat agtactattg
    16201 ttgttagagt tgtttacact acttttttga gttagttgag ttattgaaaa actacccaag
    16261 gctccactaa aaaagctaat gacgataacg actaataatt gaaaccattt tttgtaaaat
    16321 gtttttagat gtttcatatt tgcctccata tgtttgaatt actgaaagta taaactgact
    16381 agcttaatta taacttaaac acaaaagttt tacacaaact gtggataact cttttgaaac
    16441 tgtgattttc ttaattgaaa tctatttttt attttgtgaa taagatgtga aaaaatagag
    16501 aatatgttag aatagagtca tgaaaattaa agttgtaaca gttgggaaac tgaaagaaaa
    16561 gtatttaaaa gatggtatcg cagagtattc aaaacgaatt tctagatttg ctaagtttga
    16621 aatgattgag ttatcagatg aaaaaacacc agataaggcc agtgaatcag aaaatcaaaa
    16681 gattttagaa atagaaggtc agagaatttt atcaaaaatt gctgaccgtg atttcgttat
    16741 tgtgttagcc attgaaggga aaactttctt ctcagaagaa tttagtaagc agttagaaga
    16801 aacttctata aaaggatttt ctactcttac ttttattatt gggggaagtt taggattgtc
    16861 atcatctgta aaaaatagag ccaatctttc tgtcagtttt ggtcgcctaa ccttacccca
    16921 tcagttaatg agactagttc ttgttgaaca aatctatcgc gcttttacga ttcagcaggg
    16981 attcccctac cataaataga aaattgactt ttaattgaat ttttggtaga ataattgtat
    17041 taggtctcat agctcagctg gatagagcat tcgccttcta agcgaacggt cgcaggttcg
    17101 aatcctgctg ggatcaatat aatagcaaag ctgggaattt tcccggcttt tttcttaaaa
    17161 aagtacactt tgggagaaaa aaatgacagt tgagagaatt ttatctaaaa cgaaattcca
    17221 ttttgtataa tggtttttgt aagttagctt acaagaaaaa acattttagg agattttatt
    17281 atgaaaaaca cagttaaatt ggaatagttt gtagctttga aggaaaaaga cttacaaaag
    17341 attaaaggtg gggagatgag gttgtcaaaa ttcttccgtg attttatttt acaaagaaaa
    17401 aagtaatgaa ataaggggaa agagtaatgg atttatttgg atttgggacg gttattgttc
    17461 attttttaat tattagtcac agttaccatt ttatttgtaa aggtcaaata aatagaaaag
    17521 aattattcgt ttttggtgct tatacattac taacagaaat agtatttgat tttcccttat
    17581 atattctata tttagatggg ttagggattg aaagattttt atttcctttg ggattatatt
    17641 cctattttcg atggatgaaa cagtatgaga gggatagagg actattccta agtttactac
    17701 tatctctttt atatgagagc actcataact ttctgtccgt aactttctcc tctataacag
    17761 gagataattt tgttttacaa tatcatttcc cattcttttt cgttgtgacg gtgttaacct
    17821 attttgttac attaaaaatc atttactatt tccatttgga actagcctat tttgacgagg
    17881 actaccttta tcctttcttg aaaaaagtat tttttgcttt actattgcta catattgtat
    17941 ctttcgtttc agatatggta agtacgatta aacatttgaa tagttttgga agtattttgt
    18001 catctattgt ctttatctct ctccttttga ccttctttgc aatgaattct cataaagttc
    18061 aaatggagaa agagattgct ttgaagcaga agaaatttga acagaaacat ttacagaatt
    18121 acacagatga aattgttggt ctgtataatg aaatccgtgg ttttcgacat gattatgctg
    18181 gaatgcttgt cagcatgcag atggcaattg acagtggtaa tttacaggaa attgacagaa
    18241 tttacaatga agttttagtc aaagcaaatc ataaattgcg ttcagataag tacacttact
    18301 ttgatttgaa caacatagaa gactcagctt tacgaagttt ggttgctcag tcaattgtct
    18361 atgctcgaaa taatggtgta gagtttacac tggaagtaaa agatacgatt accaagcttc
    18421 caattgaact attggatttg gttcgtatca tgagcgtttt attgaataat gctgtcgaag
    18481 gatcggctga tagctataaa aagcagatgg aagtagcagt tattaagatg gaaactgaaa
    18541 cagttattgt gattcagaat tcatgtaaaa tgacgatgac tccttcagga gatctatttg
    18601 ccttaggatt ctccactaag ggaagaaatc gcggagtcgg attaaataat gtgaaagaac
    18661 tactagataa gtacaacaat attattttag aaacagagat ggaaggcagt acatttagac
    18721 aaatcattag atttaagagg gaatttgaat gaaagtttta attttagaag atgttattga
    18781 acatcaagtg agactagaga gaatattgga tgaaatttcg aaagaatcga atattccaat
    18841 atcatacaag acaacgggaa aagtccgtga atttgaagaa tacattgaaa atgatgaagt
    18901 aaatcagctt tatttcctag atatcgatat tcatggaatt gagaaaaagg gatttgaagt
    18961 ggctcagctc attcgtcatt acaatcctta cgctattatc gtctttatca ctagtcgatc
    19021 agagtttgcg actctaacct ataaatacca ggtatcagcc ctagattttg ttgataagga
    19081 tatcaatgat gagatgttta agaagagaat tgagcaaaat atcttctaca cgaagagtat
    19141 gttacttgaa aatgaagatg ttgtagatta tttcgactac aattacaagg gaaatgattt
    19201 aaaaattcct taccatgata ttttgtatat tgaaacaaca ggggtatctc ataaattgcg
    19261 cattattggt aagaattttg caaaagagtt ttatggtacc atgacagata ttcaggaaaa
    19321 ggacaaacat actcagcgat tttattctcc tcacaagtca tttttggtaa atataggcaa
    19381 tatcagagaa attgatcgaa aaaacttaga aattgttttc tatgaagacc atcgttgtcc
    19441 tatttcaaga ttaaaaatta gaaaattaaa agatatttta gagaaaaaat ctcaaaagtg
    19501 attgacaatt agcaagaaat tgatataatg gttatatctg ctacagatag aaggtccgtt
    19561 ggtcaagggg ttaagacacc gccttttcac ggcggtaaca cgggttcgaa tcccgtacgg
    19621 actattttat ccgccatagc tcagttggta gtagcgcatg actgttaatc atgatgtcgt
    19681 aggttcgagt cctactggcg gagtatagat aaaagggaac acagctgtgt tcctcttttt
    19741 gtatcaattt gtatcaccaa gcattttcat aaggaagtct gttatttctt gagaactttc
    19801 tttttttcca tgtgcaatcc aagtttggca gacaccaaaa agtgcatgag ttagatagat
    19861 gctactatat tctaattcag tggtatttag attcagttgc ataaatcgct tttgtaaatc
    19921 tgtactaagc atgatatgaa gtttatttcg taagaaattt tggatttctt tagtcccatt
    19981 ttcagaaaga agggcagcca gaagtggttc tgactctaga tattcaaaaa cttctaaaat
    20041 agcgtctctt ttgtgatgag catgtttttg aaaaatatat tcaaatgtat ggaatagctt
    20101 gctttgatag tgctcaatca tatcatactt atccttatag tgagtataga agctggaacg
    20161 actaattccg gctttttcta ctaatttgac agtagaaatt ttatcaaatg gctgttccat
    20221 cagtaattgt accatagcat tttcaatagt tcgctttgtt tttaagcgtt tgttactttc
    20281 ttgcatattt cctccttgta aacaaattag actatatgtc taaaaataga ttttttatct
    20341 tgtaatttag attttttaat gtataatcta ttatatcaaa attttagaca atatgtttaa
    20401 aaaaggagaa actatgttta aagaatggaa agcaatttaa aaaaaacaac ctttattatt
    20461 gtcatgatcg ggatttctct tattccagct ctgtacaata tcatattttt gtcatcaatg
    20521 tgggatccat atgggcaatt gtctgactta cctgtggcag ttgtaaataa tgataaagag
    20581 gcttcctata atggtaatac tatggcaata ggaaaagaca tggtgtccaa tttaaaagaa
    20641 aataaaacct tggattttca ttttgtagat gaagaggaag gaaagaaggg attggaagat
    20701 ggcgattact atatggtagt gactttacca agtgatttat ctaaaaaaac aactacatta
    20761 tccaatattc aatcgacagc agcttatcaa tcattgacaa gtgagcaaca aactgggata
    20821 agtgattctg tatctcaaaa ttcaactgat agtattcaat cggctcagtc aattgtagct
    20881 ttagtacaag gtttacaggg aagtttagaa aacttacaaa atcaatcttc taatctttcg
    20941 actttaaaaa atcaagctaa tcaagtatta cctattactt ctacttcttt gataggattg
    21001 tcaagtggat taacagagat acaaggagct gttactagca aattagttcc tgccagtcag
    21061 ttgattgcat caggtgtaaa cgcatatact acaggtgttg ataaagtttc tcagggcgca
    21121 agtcaactaa gtgaaaaaaa tgccaccttg acaggtagtt tggataaact agtttcaggc
    21181 tcaaacacct tgacacaaaa atcttctaga ttgacagcag gagttagtta attacaatca
    21241 ggatctgggc aattagcaga caaatccagt cagttacttt caggtgcttc tccattagag
    21301 aatagagcta ataaattggc agatggatct gggaaactag cagaaggtgg aacaaagtta
    21361 acttctggat tggaagattt acagacagga cttgcttctt taggacaagg actaggtaat
    21421 gctagtgatc aactcaaatc agtatcaaca gaatctaaaa atgcagagat tttgtcaaat
    21481 ccactcaatc tttcaaaaac agacaatgat caagttcctg taaatgtaat cgcaatagct
    21541 ccttatatga tatcagttgc tctttttgtt gcagcaatat caacaaatat gatatttgcg
    21601 aaattgcctt caggacgtca tccagagagc cgttgggctt ggttgaaatc ttgagctgaa
    21661 ataaatggta ttatagctgt tttggcagga attttggtat atggaggagt tcagcttatt
    21721 ggtttaactg ctaatcatga gatgagaata tttattctca tcatcctaac aagtttagta
    21781 ttcatgtcta tggtgaccac tttagcaacg tggaatagcc gtataggagc ttttttttca
    21841 cttattttgc ttttactaca gttagcatca agtgcaggta cttattcact tgctttgaca
    21901 aatgatttct ttagatctat taatccctgg ttaccaatga gctattcagt ttcgggatta
    21961 cgacaaacaa tctctatcaa caagtcattt tcctagctgt catactagct ctatttactg
    22021 gtttaggtat gctagcctat caacataaga aaatggaaga agattaaaaa aatcgaccga
    22081 ttaactggtc gattttttat gccttagatg actttcgtct gtgattatag attccaaata
    22141 gtaagagaga agtaaaggaa cagattgctc cagtcataaa accattggga atgaaggaaa
    22201 gtgtaatagt tcctttcccc ttgggaatgt caactttcat aaatccagtt tgagcttgtt
    22261 taatttctat tttcttacca tcttggtagg cagaccaacc tttgtcataa ggaatggtga
    22321 agaaaataga tgtatcttgt tggacatcat atgtagcaaa aaccttgttt ttagaagttg
    22381 atactgtgac aggttgttct ttaatttttt gaattgcctc ggtgaaagtt ttggtatcta
    22441 aacgatagaa ggtaggagat tcaaatgata cttgtgaatt tccagggaaa ctaacattga
    22501 tattgaaagt ttttttctct ttagtatatc ctagattaaa gaaggagaag acattatcag
    22561 ttgtaaaagt ctttttttca ccatttacaa ggatgtcaac cttcttttgt ttatcgttag
    22621 aaaagtgaag gtttatgaaa gagagataaa cttggctgtt ttctggaact tcaatttgat
    22681 actggattgc tgcatcttca tttgaagaac ttgtgacact aatcaaatca ttagtatttt
    22741 ctattttttc tgttttttca taaggtattg gagaaaaata atcaaaattg acgttagcaa
    22801 gttgatttaa aaatgaggcc tgattatcca aggtatgttc attgaacttg acatcattgt
    22861 aaacagattg actagcaact gcaatcggaa gagagtattg attttcatat agggtaagat
    22921 tatctttttg atagatatct ttaaagccat acttatcaat aggactgtct gagatattgt
    22981 actggatacc aaataaacta tcagccaaaa tactattatt tgcatatcgg agattgagat
    23041 tagtcccaga ggatttaaaa ccaagtttat ctaaagtaga gcttgatgaa cgatttcgaa
    23101 cagatgaaaa ttgagagatt ccattgtagt tgaatttcat actgtcattt cctgtctgag
    23161 tttgtagttt ttcagtacga gtaaattgat ttccaatata tgttgagaaa gattccatag
    23221 ctgggatatc tcgactataa gcacttcgag aagcaaatcc ccattcctta gcaattccgt
    23281 ccatttgaga tgaagcattt aaactcattt caaccagtat aaataaagag attagaatgg
    23341 caaatagatt cacagatata aactttttga taactgcaag gagtaaaaga gaatagacaa
    23401 ccaaaaattc aagagtaagc agaatattca aatctgttaa aaaagaataa tgcgatttta
    23461 gatagatggt agctaaaaat cctgctacta caagaaaaag cgaaactaaa aaattccaga
    23521 ctttaagttc tttcagacgc tttaagactt ctgctgctgt gtaaattaac aaggtagaga
    23581 aaatccaagc atagcgatgt aaaaacatgt ttggagtatg catgccttgc caaaataagt
    23641 caagagcttc tatgtaaaag cttgcaatta gaaatgcaaa gaatattaca tatatgagtt
    23701 tcacgtgaaa cttaatagat ttcagcgtaa aaaataaaat ggtcaaaata aagggaaata
    23761 gtccaacaaa aatcattggg atggccccat actttgttgt gtcaaaggaa ccaatgaatt
    23821 gcttagcaaa gagatcaaga taccagctac tttcagtttg aaactttgta acttcagtca
    23881 atttttcccc atgtgtctgt aaatcaaata gagtgggaag agtcataatc aaactagcca
    23941 taccagctaa aaaggagata actatgaaat caagaacaga tgattttcga gtcttaaagt
    24001 cccacgaaat ttgacagaga taccagaaaa taagaaacaa tactgtcata tatccaaaat
    24061 aataattttg aataaataag attgacagac ttgtaaagta caataggagt ttcttttcag
    24121 ttatcagtag atgtaaacca gttataatta aaggaatcaa gataaaaaca tctagccagg
    24181 tttttatctc taattgactg acagtgaaac tcatcagagc ataggaagta gataaggcta
    24241 gttttaaagt ctgagggata gattgaaaca atttattcaa actaaaaaag gttgacagac
    24301 caatcaatcc aaattttaag agagtggtca gatagacagc acctggcata ttcgttagat
    24361 caaaaaagta aactagaggc gcgagaaaac tacccaagta ataactagat agggcataga
    24421 agtttagccc tagaccactt gtaaaggtgt aaaacagact actatttcca tgtaggatat
    24481 ttcgtaaggc tacatcaaaa ataacgtatt gatgaaagcc atctcctaat agaggagagt
    24541 tgtcgctatt ccagtagata ccttgagata gatatactcc agacataatc actacaggaa
    24601 tgatgaaaga aataaaatag gttcgatatg tttttaaaaa tgatttcatg ttacctcgta
    24661 gaatgataga aaactcagtt ggttaaccca actgagtttt gaagttttat ttagtctttc
    24721 caaagttctt taacttttgc ttgtacttct gcattttcta ggaattcatc gtaggtttca
    24781 tcgatacggt caatgacgcc atttttagat aagacaatga tatggttagc caaagtttga
    24841 ataaattcgt ggtcatggct agcaaagatg attgattctt taaagttttt caatccatca
    24901 ttcaagcttg agatagattc caagtccaag tgatttgttg gatcatcaag tacaaggaca
    24961 tttgatttta agagcatgag ttttgaaagc atgacacgaa ctttttctcc ccctgacaag
    25021 acatttacag gtttgttaac ttcatctcca gagaagagca tacggccgag gaagccacgt
    25081 aggaaagtat tgtcatcttc ttctttactt gcgaattgac gcaaccagtc aagaattgat
    25141 tctcctcctg caaaatcagc tgagttatct tttggtaggt aagattgact agttgtaact
    25201 ccccacttga cagttccttc atagtcaata tctcccatga ttgcacgaat taatgcagtc
    25261 gtttgaatat cattttgtcc aataagtgct gtcttatcat ctggacgcaa gatgaaacta
    25321 atattatcca agatagtttc accatcaatc tttacagtta gattttctac tgtcaagaga
    25381 tcattaccaa tctcacgttc cgctttaaag ttgataaatg gatatttacg actagatggc
    25441 acaatctctt ctaactcaat cttatcaagc attttcttac gtgatgttgc ctgccttgac
    25501 ttagaagcat tggcagagaa acgagcaaca aattcttgca attgtttaat tttttcttct
    25561 gctttagcat tacggtctgc tagcaattta gcagcaagct cagaagattc cttccagaag
    25621 tcgtagtttc cgacatagag tttgattttt ccaaagtcaa ggtcggccat gtgagtacaa
    25681 actttgttta agaagtgacg gtcgtgggat actacgataa ctgtgttatc aaagtcaatc
    25741 aagaagtctt ctaaccaagt aatcgattgg atatccaaac cgttagtagg ctcgtccaag
    25801 agaagaacat ctggtttacc aaaaagtgct ttggcgagga gaacctttac tttttcaccg
    25861 ttggccaatt cgctcatgtt ttggtagtgt aattcttctg gaatgtttag gttttgaagt
    25921 agttgagagg cttcactctc tgcttcccaa cctccaagtt cggcaaactc tccttcgagt
    25981 tcggcagcac gaaccccgtc ctcgtctgag aaatcttcct tcatgtagat agcatctttc
    26041 tctttcatga tgctataaag tttttcattt cccatgataa cgacatcaat ggcacgttca
    26101 tcttcgtagt caaagtgatt ttgacgaaga acagagagac gttcatctgg accaagagag
    26161 atgtgaccag tagtaggttc gatatctcca gctaaaattt ttaaaaaggt tgattttccg
    26221 gcaccattag caccgattaa tccgtaagta tttccttctg taaatttgat attgacatca
    26281 tcaaaaagtt tgcgatcact aaaacgtagt gaaacatcag atactgtaag caatgttttt
    26341 ctcctatatg tgtaatatat ttattctact agaaaataca gaaatattca aatttttatt
    26401 tgtcaatttt gtgtaaatta tatttacagt atcctttaca caaatctgta aaaagcaagg
    26461 ctgatttatt ttgataaatt acggttattt catttaaaaa atgctataat tgaaaggact
    26521 atatcgaagg agaacaaaat gactaaaccc attattttaa caggagaccg tccaacagga
    26581 aaattgcata ttggacatta tgttggaagt ctcaaaaatc gagtattatt acaggaagag
    26641 gataagtatg atatgtttgt gttcttggct gaccaacaag ccttgacaga tcatgccaaa
    26701 gatcctcaaa ccattgtaga gtctatcgga aatgtggctt tggattatct tgcagttgga
    26761 ttggatccaa ataagtcaac tatttttatt caaagccaga ttccagagtt ggctgagttg
    26821 tctatgtatt atatgaatct agtttcgtta gcacgtttgg agcgaaatcc aacagtcaag
    26881 acagagattt ctcagaaagg atttggagaa agcattccga caggattctt ggtctatcca
    26941 atcgctcaag cagctgatat aacagctttc aaggctaatt atgttcctgt tgggacagat
    27001 cagaaaccaa tgattgagca aactcgtgaa attgttcgtt cttttaacaa tgcatataac
    27061 tgtgatgtct tggtagagcc ggaaggtatt tatccagaaa atgagagagc agggcgtttg
    27121 cctggtttag atggaaatgc taaaatgtct aaatcactaa ataatggtat ttatttagct
    27181 gatgatgcgg atactttgcg taaaaaagta atgagtatgt atacagatcc agatcatatc
    27241 cgcgttgagg atccaggtaa gattgaggga aatatggttt tccattatct agatgttttt
    27301 ggtcgtccag aagatgctca agaaattgct gatatgaaag aacgttatca acgaggtggt
    27361 cttggtgatg tgaagaccaa gcgttatcta cttgaaatat tagaacgtga actgggtcct
    27421 attcgtgagc gccgtattga atttgctaag gatatgggag aagtttataa tatgattcaa
    27481 aaaggtagtg aaagagcgcg tgaagttgcg ggtcaaaccc tatctgaggt aaaaggggca
    27541 atgggacttc attactttaa ctaagtttat tttacaagaa actatctttt ctatctcgaa
    27601 gaaaagatag ttttttattt acccctgtaa catttgacaa atttttatag aatggtatga
    27661 tagatacaat ataaaaagag tcaagctcaa aaagaaagaa aagaggaaac ttcgaatgtc
    27721 taattgggac actaaatttt tgaaaaaagg ttttaccttt gatgatgtat tgcttattcc
    27781 agctgaaagt catgtgttgc ctaacgatgc agatttaaca actaaattgg cagataattt
    27841 gactttaaat atcccaatta ttaccgctgc catggacaca gttacagaga gtcaaatggc
    27901 cattgctatt gctcgtgcag gcggtctcgg agttatccat aaaaacatgt caattgctca
    27961 acaagcagac gaggttcgta aggtaaaacg ttctgaaaat ggagttatta ttgatccgtt
    28021 cttcttgacg cctgaacata caattgctga agcagatgag cttatgggtc gttaccgcat
    28081 cagtggtgtt ccagttgttg aaacacttga aaatcgtaaa ttggttggta ttttgacaaa
    28141 ccgagatctt cgttttattt cagattataa tcaaccaatt tcaaaccata tgactagtga
    28201 aaatcttgtt actgctcctg tgggtacgga tcttgcaacg gctgagagta ttcttcaaga
    28261 gcatcgtatt gaaaaacttc cgttggtcga tgaagaaggc agtctttctg gtttgatcac
    28321 tatcaaagat attgaaaaag ttattgagtt tccaaatgca gctaaagatg agtttggtcg
    28381 tcttctagtt gcaggtgcag taggtgttac ttcagataca tttgaacgtg cagaggctct
    28441 ttttgaggca ggagcggatg cgattgttat tgatactgca catggtcatt ctgcaggtgt
    28501 cttgcgtaaa attgccgaga ttcgtgctca tttcccagat cggactttga ttgctggaaa
    28561 tattgctact gctgaaggtg cacgtgccct ttatgaagcg ggtgtagacg ttgttaaggt
    28621 tggtattgga ccaggttcta tctgtactac tcgtgtgatt gctggtgttg gtgttccgca
    28681 agtaacagct atctacgatg ctgcagctgt tgcgcgcgaa tatggtaaaa cgattattgc
    28741 tgacggtggg atcaagtatt ctggagatat tgtaaaagca cttgctgcag gtggaaatgc
    28801 tgttatgctt ggatctatgt ttgctggaac tgatgaagct ccaggcgaaa ctgaaatctt
    28861 ccaaggacgt aaattcaaga cttaccgtgg tatgggatca attgctgcta tgaagaaagg
    28921 ttcaagcgac cgttatttcc aaggttctgt caatgaagca aacaagcttg ttccagaagg
    28981 aattgaaggt cgtgttgctt ataaaggagc ggcagctgat attgttttcc aaatgattgg
    29041 tggtattcgc tctggtatgg gttactgtgg tgcagctaac cttaaagaac tacacgataa
    29101 tgctcaattt attgaaatgt ctggtgctgg tttgaaagaa agccatcctc atgatgtgca
    29161 aattactaat gaggcaccaa attattctat gtaaaaaaca atgaaaagaa ctccagtgaa
    29221 aacaggagtt cttttacaat ggtgtcaatt tccatttaca gcaactttac catcctgaat
    29281 agtgaagata cttagatttt ctggcagatt ttgaagatgg tctaagcttg ttgttgtgat
    29341 aaaggtttgg attgattgag aaatcgtttc taataatttt aactgtctag tgttgtcaag
    29401 ttcactcatc acatcgtcaa gcagtaatat aggagattct gtggtaatgc tttccattaa
    29461 ttcgatttct gctaatttta tcgagaggac gagactacga tgttgacctt ggcttccgaa
    29521 actagcatcc atcccattta tataaaaaga aatgtcatct cgatgaggac cgacaccagt
    29581 attcttttta aataaatctc tggatctact tttttctaaa gcaattttga aagattcgga
    29641 taagttttgt ttgtcagtta tattgacaga agattgatag gatattgaca actcttcgat
    29701 ctgattagag agttcaaaat gtttcttacg cccaaatgat tctagttttt ttatgaaatc
    29761 taagcggtga ttcattacac gacatccata atcaactagc tgatcatcta acacagaaag
    29821 gaatgtttca tctatttttt gagctgattt taggtaagtg tttctttgct ttaggatgtg
    29881 gttataattg gttaagtcag ataaatagat tggcttaatt tgcccaagtt ccatatcaat
    29941 gaattttcgt cgaatcgaag gtgctccttt aattagttgt aaatcttcag gagcaaataa
    30001 gacaacattc atgtgtccta cataatctga aaggcgtgcc tgttttaagt gattaacttt
    30061 tgttacacga cctttttgtg ttagttcgat ttctagggga atggatccag tttttttctg
    30121 aacgagacct gaaagatgaa gttgttcctc atcaaaatga atgagatttt tatctgttcg
    30181 agttcgatga ctacgcgtta aggctaaaaa atagatagcc tctaacatgt ttgtttttcc
    30241 ttgtgcatta cgtcccaaaa agacattcaa tttaggatta aagtctattt tcgtttcttt
    30301 gtaattacga aaagtcttga gagatagatg ttgtagccac atgattatct accagggaat
    30361 cgtggagctt gttggctttt aggtgatgaa gcaggtttcg atttgtcttt tttaactccc
    30421 ttattcatct ttttgacaag tttagcgatc cgttcttttt caactttatc agcttggtat
    30481 tcatcttgtt cttcagaagt aggttgtgtc aacaagatgt caatgttcat gtcagggatg
    30541 tcaactttat cgccaatacg aagttttttt ccacgacggc tctctaattc cctattaaag
    30601 taaacagaat gttcagagag aaatgattta atagctcctc cgctatgtgt aattccaagt
    30661 tctttgaata gtgcttggag ggtaataaat tcttcaaata atttgtattc cataattcac
    30721 ctcaatcttt ggtattatac catattttcc taaaaatagt gagagagaca gcgagaaatg
    30781 taagcgattt ttatttcaaa agtgttacag ggaacaagaa aatttcaggt tttcgtgata
    30841 taatagaagt ctgtatataa ggaggtaaat catggagtta gtgcatggaa tttcaacaca
    30901 ttttatccaa tcaaaaaagt ttaaaacaaa caaaattacc gtgcgtttta ccgctccatt
    30961 atcccttgat acgattgcag gtcacatgtt gagtgcaagt atgctagaga ctgctaatca
    31021 gatgtacccc acttctcaag atttgaggag acacttggcc agtctatacg gtacagatat
    31081 gtcaaccaat tgtttcagaa gagggcaaag ccacattata gaattgacat ttacctatgt
    31141 tcgtgatgag tttttaagta ggaaaaacgt gctaacctct cagattttgg aacttgtaaa
    31201 agaaactctt ttttcacccg tagtagttga taatgggttt gatccggcct tatttgaaat
    31261 tgagaaaaaa caattgctag caagtttagc agctgatatg gatgattctt tttattttgc
    31321 acataaagaa ttggataaat tgttttttca tgatgaacgt cttcaattgg aatatagtga
    31381 tttacgaaat cgtattttag ctgaaactcc acaaagttct tattcttgtt tccaagaatt
    31441 tttagccaat gatcgaatag atttcttttt cctaggtgat tttaatgagg ttgaaattca
    31501 aaatgtatta gaatcatttg gctttaaagg tcgaaaagga gatgtgaagg ttcagtattg
    31561 tcaatcttat tctaatatcc ttcaggaagg tatggttcgg aaaaatgtgg gacaatccat
    31621 tttggaatta ggttatcatt accgttctaa atatggtgat gaacaacatt tacccatgat
    31681 tgtaatgaat ggtttacttg gtggatttgc tcactctaag ctctttacaa atgtccgtga
    31741 aaatgctgga ttagcttata ccatttcaag tgagcttgat ttatttagtg gattcttgag
    31801 gatgtatgct ggtatcaatc gagaaaatcg taaccaggct cgtaaaatga tgaataatca
    31861 actgcttgat ttaaaaaaag gttattttac agagtttgag ttaaatcaga ccaaggaaat
    31921 gattcgttgg tcgttgttac tttctcaaga taatcaatct tcattgattg aacgtgctta
    31981 tcaaaatgcc ttatttggaa aatcttcagc agactttaaa agttggattg caaagcttga
    32041 acaaattgac aaagatgcta tttgtagagt agctaataat gtgaaactac aagcgattta
    32101 ctttatggaa ggaatagaat gacaaaggtt gtttttgaag aaaaatacta tccagctgta
    32161 aaagaaaagg tttatcgaac tcgtttggcc aacggattga cagttgctct tttgcctaaa
    32221 aaggaattta aagaggttta cgggagtgta actgtacagt ttggttcgat agatacgctt
    32281 gtcacagaag ttgacggaga tgtaaaacaa tatcctggag gaattgctca ttttcttgaa
    32341 cataaattat ttgagagaga agattctagt gatttgatgt cggcttttac gagtctaggt
    32401 gcagatagta atgcctttac aagctttaca aaaacaaact atcttttttc agcaacggat
    32461 tattttttag aaaatttaga tttacttgat gaattggtaa catcagcaca ctttactgaa
    32521 gcttccattc tgacagagca ggatattatt cagcaagaac gagaaatgta ccaagatgat
    32581 ccagattcgt gtttattctt ttcaacttta gcgaatttgt atcctggtac acctttagca
    32641 actgatatag ttggaagtga ggagtccatt tcccaaatca atctaactaa tttgcaagaa
    32701 aattttacaa agttttacaa acctgtaaac atgtctctgt ttttagttgg taattttgat
    32761 gtggagcgag tacaggacta ttttgaaagc aaagaactga aagattcaga ttttcaggaa
    32821 gtagcaagag aaaagttgtt tttacagcct gtaaagccaa cagatagtat gagaatggaa
    32881 gtatcttctc ccaaactagc gattggagtt agaggtaagc gagaagtttc tgaagcggat
    32941 tgctatcgac atcatatttt attaaaatta ttgtttgcaa tgatgtttgg ttggacttcg
    33001 gatcgttttc aaaaatgtta tgaatcaggt aaaattgatg cgtccttatc tctggaagtt
    33061 gaaataacaa gtcgctttca ttttgtcatg ttgacaatgg atacgaaaga gccagttgct
    33121 ttgtctcatc aatttaggaa ggctattcgt aattttacaa aggatttaga tattacagag
    33181 gaacatttag atattatcaa aagagagatg tttggcgaat ttttcagtag catgaactct
    33241 cttgaattta ttgcaacgca atatgatgct tttgaaaatg gtgagacaat ttttgatttg
    33301 ccgaaaattt tacaggaaat tactttagag gatgtccttg atgctggaca tcatttaata
    33361 gatgatggtg acatagttga ttttacaata ttcccatcgt agtaacctat cataatagac
    33421 actagaaaga agggatgaca agtatgagaa aaaaaacaat tggagaggtt ttacgattag
    33481 ctagaatcaa tcagggattg agtttagatg aattgcagaa aaagacagaa atccagttag
    33541 atatgttgga agcaatggaa gcagacgatt tcgatcaact tccaagtcct ttttacacgc
    33601 gttctttctt gaaaaaatat gcatgggctg ttgagttaga tgaccaaatt gttttggatg
    33661 cttatgattc tgggagtatg attacttatg aggaagtaga tgttgatgaa gatgagttga
    33721 caggtcgtag acgttcaagt aagaaaaaga agaaaaaaac atcattttta cctttatttt
    33781 attttatcct ttttgcttta tcgattttaa tttttgtgac ttattatgtt tggaactata
    33841 ttcaaactca accagaggag ccttctcttt ctaattacag tgtggttcaa tcaacaagtt
    33901 caactagctc tgttccccac tcctcaagta gtagttcttc tagtatagaa tcagctataa
    33961 gtgtatcagg cgaaggaaat catgtagaaa tcgcttataa gacaagtaag gaaacagtta
    34021 aattgcaatt ggcagtttca gatgttacaa gttgggtcag tgtttcagaa agcgaacttg
    34081 agggcggtgt aaccttatcg ccaaagaaga aaagtgcaga agcaacagtt gcaactaaaa
    34141 gtcctgtaac aattacgtta ggtgttgtaa aaggtgttga tttgacagta gataatcaga
    34201 ctgttgattt atcgaaatta acagctcaga ctggacaaat cactgtaacc tttactaaaa
    34261 attaaggaaa aacgaatgaa aaaagaacaa attcccaatc tcttaacaat aggtcgaatt
    34321 ctctttatac ctatttttat ctttatttta acgataggaa attcgataga gagtcatata
    34381 gttgcagcta ttatctttgc tgttgccagt attaccgact atttagatgg atatttagct
    34441 cgtaaatgga atgtggtcag taattttggt aaatttgcag atcctatggc ggataagtta
    34501 ctagttatgt cggcttttat tatgttgatt gagttaggta tggctccggc ttggattgtt
    34561 gcagtgatta tctgtcgtga gttagctgtg acaggtttaa ggcttttatt ggttgaaact
    34621 ggtggaacaa ttttagcagc agcaatgcct ggaaaaatta aaacttttag tcagatgttt
    34681 gccattattt tcttgctatt acattggact ttgcttggtc aagttctact ttatgtagcc
    34741 ttatttttca ctatctactc tggctatgac tatttcaagg gtagtgccta tgtatttaaa
    34801 gggacatttg gttcgaaatg aaatcaataa ttgatgtaaa aaatctttct tttcgctata
    34861 aagaaaatca gaactactac gatgtgaagg atattacgtt tcacgtgaaa cgtggagaat
    34921 ggctttcgat tgtagggcat aatggtagtg gtaaatcaac gacggttcga ttaattgatg
    34981 gcttactgga agcagaatcc ggagagattg taattgatgg ccaacgtttg actgaggaaa
    35041 atgtttggaa tatacgtcgt caaatcggta tggtttttca aaatccagac aatcaatttg
    35101 ttggagcgac tgttgaagat gatgttgctt ttggtttgga aaatcaggga ctttctcgtc
    35161 aagaaatgaa aaagagagta gaagaagctc tggctttagt tggcatgttg gactttaaaa
    35221 agagagagcc agcgcgtcta tcaggtggcc aaaagcaacg tgtggccatt gcaggtgttg
    35281 tagccctaag accagctatt ttaatcttag atgaagcaac gagtatgttg gatcctgagg
    35341 ggcgtagaga acttattggg acagtaaaag gaattcgaaa agactatgat atgacggtca
    35401 tttctattac ccatgatttg gaagaagtcg ccatgagtga tcgcgtattg gtcatgaaaa
    35461 aaggggaaat tgaatcaact agtagtccaa gggagctttt ctctcgaaat gatttagatc
    35521 aaattggatt agacgatcct tttgctaatc aattaaaaaa atctttgagc cagaatggct
    35581 atgatttacc tgaaaattat ttgacagaaa gtgagctaga ggataagcta tgggaattgc
    35641 tctagaaaat gtgaatttta catatcaaga aggtactccc ttagcttcag cagctttgtc
    35701 ggatgtttct ttgacgattg aagatggctc ttatacagct ttaattgggc acacaggtag
    35761 tggtaaatca actattttac aactcttaaa tggtttattg gtgccaagtc aagggagtgt
    35821 gagggttttt gataccttaa tcacctcgac ttctaaaaat aaagatattc gtcaaattag
    35881 aaaacaggtt ggcttggtat ttcagtttgc tgaaaatcag atttttgaag aaacggtttt
    35941 gaaggacgtt gcttttggac cgcaaaattt tggagtttct gaagaagatg ctgtgaagac
    36001 tgcgcgtgag aaactggctc tggttggaat tgatgaatca ctttttgatc gtagtccgtt
    36061 tgagctgtca gggggacaaa tgagacgtgt tgccattgca ggcatacttg ccatggagcc
    36121 agctatatta gtcttagatg agccaacagc tggtctagat cctctaggga gaaaagagtt
    36181 gatgaccctg ttcaaaaaac tccaccagtc agggatgacc atcgtcttgg taacgcattt
    36241 gatggatgat gttgctgaat atgcaaatca agtctatgta atggaaaagg gacgtttagt
    36301 aaaggggggc aaaccaagtg atgtctttca agacgttgtt tttatggaaa aagttcagtt
    36361 gggagtacct aaaattacgg ccttttgtaa acgattggct gatagaggcg tgtcatttaa
    36421 acgattaccg attaagatag aggagttcaa ggagtcgcta aatggatagt atgattttgg
    36481 ggcgttatat cccaggggat tcgattgttc accgattgga tccacgtagc aaattgcttg
    36541 ctatgatgct actgattttg attgtgtttt gggctaataa ccccttgacg aatctgattc
    36601 tttttatagc gacagggata tttattgcct tgtcaggagt atctctttca ttttttattc
    36661 agggcttgaa gtctatgttt ttcttgattg ccttcacaac tatttttcaa ctatttttca
    36721 tttctaatgg gaatgtttta tttgagtttt cgtttgtgag aatcacggat tatgctttgc
    36781 aacaagctgg gattattttt tgtcgctttg tattgattat tttcttttca actttgttaa
    36841 ccttaacaac catgccttta agtttggcat cagctgtcga agctttatta gcacctttaa
    36901 agcgtgtgaa agttccagtt catgaaattg gattgatgct gtctatgagt ttgcgttttg
    36961 tcccaacctt gatggatgat acgactcgga ttatgaatgc acagaaagct cgtggagtgg
    37021 attttggaga aggaagcatc gttcaaaaag taaaggcgat gattcccatt ttgattcctc
    37081 tttttgcgac aagtttaaaa cgtgcagatt ccttggctat cgctatggaa gcgcgtggct
    37141 atcagggtgg aaaaggcaga agtcaatacc gacaattgaa atggactcta aaggatacgc
    37201 tgaccattct tgttattctc gtacttggtt gttgtttatt tttcttaaaa tcttagtagc
    37261 tttcaggaat tgataaaaag ttactgtaac agtttttgat agaaaggtag ggatatgaac
    37321 cgttttaaaa aatcaaaata tgtcattatt gtttttgtca ctgttctgct tgtgtcagct
    37381 ctcttagcga cgacttattc aagtacaatt gtgacaaaat taggagatgg aatctcattg
    37441 gttgatagag ttgtacaaaa accttttcag tggtttgatt ctgtcaaatc agatttggct
    37501 catttgacac gaacatataa tgaaaatgaa agtttgaaga aacagcttta ccaattagaa
    37561 gttaaatcaa atgaggtgga aagtttaaag acagaaaatg aacaactgcg ccaattgctt
    37621 gatatgaagt ctaaattgca agccacaaag actttagcag cagatgttat tatgcgttct
    37681 ccggtatctt ggaagcagga gttgacctta gatgcaggta gatcaaaagg tgcttctgag
    37741 aacatgttag ctattgcaaa tggtggcttg attgggagtg tttcaaaagt agaggagaac
    37801 tctactatag tcaaccttct gacaaatacg gaaaatgctg ataagatttc tgttaaaatt
    37861 caacatggct ctactacaat ttatggaatt attattggct atgacaagga aaatgacgtt
    37921 cttaaaatta gccaattaaa tagtaatagc gatattagtg cgggagataa ggtgactact
    37981 ggtggattag gaaactttaa cgttgctgat attcctgttg gtgaagtggt tgccacaacg
    38041 catagtacag actatttgac acgagaagta actgttaaat tgagtgcaga tactcataat
    38101 gtagatgtga tagaattagt ggggaattca taatgagaca gttgaagcga gttggagtat
    38161 ttttattgct tcctttcttt gttctaattg acgcccatat tagccagctt ctgggctcat
    38221 ttttccccca tgtacatttg gctagtcatt ttctttttct atttctctta tttgagacga
    38281 tagaagtatc agagtatctc tacctagtct attgttttgc tataggcttg gtttatgatg
    38341 tttacttttt ccatctaata gggattacaa ctctcttatt tatcttattg ggagccttcc
    38401 ttcataaatt gaatagtgtt attttgttga atcgttggac aagaatgcta gctatgattg
    38461 tgctgacatt cctgtttgaa atgggtagtt atcttttggc ttttatggta gggttgacag
    38521 tagatagcat gtcgattttt atagtctata gcttggtacc gacgatgatt ttaaattttt
    38581 tatggattac tgtttttcaa tttatttttg aaaaatatta tctataagaa cgacatataa
    38641 atgtaacaaa ggcgtaatat ttattaggcc tttttttggt atactagtat tgtctttaaa
    38701 agaaggagta tctacgtaat atgaagaaaa aaatcttagc gtcactttta ttaagtacag
    38761 taatggtttc tcaagtagct gttttaacaa ctgcgcatgc agaaacgact gatgacaaaa
    38821 ttgctgctca agataataaa attagtaact taacagcaca acaacaagaa gcccaaaaac
    38881 aagttgacca aattcaggag caagtatcag ctattcaagc tgagcagtct aacttgcaag
    38941 ctgaaaatga tagattacaa gcagaatcta agaaactcga gggtgagatt acagaacttt
    39001 ctaaaaacat tgtttctcgt aaccaatcgt tggaaaaaca agctcgtagt gctcaaacaa
    39061 atggagccgt aactagctat atcaatacca ttgtaaactc aaaatcaatt acagaagcta
    39121 tttcacgtgt tgctgcaatg agtgaaatcg tatctgcaaa caacaaaatg ttagaacaac
    39181 aaaaggcaga taaaaaagct atttctgaaa aacaagtagc aaataatgat gctatcaata
    39241 ctgtaattgc taatcaacaa aaattggctg atgatgctca agcattgact acgaaacagg
    39301 cagaactaaa agctgctgaa ttaagtcttg ctgctgagaa agcgacagct gaaggggaaa
    39361 aagcaagtct attagagcaa aaagcagcag ctgaggcaga ggctcgtgca gctgcggtag
    39421 cagaagcagc ttataaagaa aaacgagcta gccaacaaca atcagtactt gcttcagcaa
    39481 acactaactt aacagctcaa gtgcaagcag tatctgaatc tgcagcagca cctgtccgtg
    39541 caaaagttcg tccaacatac agtacaaacg cttcaagtta tccaattgga gaatgtacat
    39601 ggggagtaaa aacattggca ccttgggctg gagactactg gggtaatgga gcacagtggg
    39661 ctacaagtgc agcagcagca ggtttccgta caggttcaac acctcaagtt ggagcaattg
    39721 catgttggaa tgatggtgga tatggtcacg tagcggttgt tacagctgtt gaatcaacaa
    39781 cacgtatcca agtatcagaa tcaaattatg caggtaatcg tacaattgga aatcaccgtg
    39841 gatggttcaa tccaacaaca acttctgaag gttttgttac atatatttat gcagattaat
    39901 ttacagaggg actcgaatag agccctcttt tcaggtttta ccgtgacaat ccctattaaa
    39961 aattatatca aaatagcttg aaaatattgg aaaagtatgg tagaatgaaa attgtcgtgt
    40021 gaacgataat actcattctt gatgaattgt gaagcagttg cccttgggtc gttttgcgag
    40081 ttgaagtcaa gaagaggaaa aaaacaaaaa ggagaaatac tcatggcagt aatttcaatg
    40141 aaacaacttc ttgaggctgg tgtacacttt ggtcaccaaa ctcgtcgctg gaatcctaag
    40201 atggctaagt acatctttac tgaacgtaac ggaatccacg ttatcgactt gcaacaaact
    40261 gtaaaatacg ctgaccaagc atacgacttc atgcgtgatg cagcagctaa cgatgcagtt
    40321 gtattgttcg ttggtactaa gaaacaagca gctgatgcag ttgctgaaga agcagtacgt
    40381 tcaggtcaat acttcatcaa ccaccgttgg ttgggtggaa ctcttacaaa ctggggaaca
    40441 atccaaaaac gtatcgctcg tttgaaagaa attaaacgta tggaagaaga tggaactttc
    40501 gaagttcttc ctaagaaaga agttgcactt cttaacaaac aacgtgcgcg tcttgaaaaa
    40561 ttcttgggtg gtatcgaaga tatgcctcgt atcccagatg tgatgtacgt agttgaccca
    40621 cataaagagc aaatcgctgt taaagaagct aaaaaattgg gaatcccagt tgtagcgatg
    40681 gttgacacca atactgatcc agatgatatc gatgtaatca tcccagctaa cgatgacgct
    40741 atccgtgctg ttaaattgat tacagctaaa ttggctgacg ctattatcga aggacgtcaa
    40801 ggtgaggatg cagtagcagt tgaagcagaa tttgcagctt cagaaactca agcagattca
    40861 attgaagaaa tcgttgaagt tgtagaaggt gacaacgctt aatttataca aatagtaatt
    40921 acctaggagg gcggggctta gcccggctct cctattttca aaaaatatag gagaattaaa
    40981 atggcagaaa ttacagctaa acttgtaaaa gagttgcgtg aaaaatctgg tgccggtgtt
    41041 atggacgcta aaaaagcgct tgtagaaaca gacggtgaca tcgaaaaagc gattgaattg
    41101 cttcgtgaaa aaggtatggc taaggcagct aagaaagctg accgtgttgc tgcagaaggt
    41161 ttgactggtg tttatgttaa cggtaatgtt gcagcagtta ttgaagtaaa cgctgaaact
    41221 gacttcgttg caaaaaacgc tcaattcgtt gaattggtaa atactacagc taaagtcatt
    41281 gctgaaggaa aacctgctaa caacgaagaa gctcttgctt tgataatgcc ttcaggtgaa
    41341 actcttgaag ctgcatacgt atctgcaaca gcaactatcg gagagaaaat ctcattccgt
    41401 cgctttgcat tgattgaaaa aacagacgca caacactttg gagcatacca acataacggt
    41461 ggacgtatcg gtgttatttc agttgttgaa ggtggagacg aagcacttgc taaacaattg
    41521 tcaatgcaca tcgcagcgat gaaaccaaca gttctttctt acaaagaatt ggatgagcaa
    41581 ttcgttaaag atgagttggc acaattgaat cacgttatcg accaagacaa cgaaagccgt
    41641 gcaatggtta ataaaccagc tcttccacac ttgaagtatg gatcaaaagc tcaattaact
    41701 gatgatgtta ttgctcaagc tgaagctgac atcaaagctg aattggctgc agaaggcaaa
    41761 ccagaaaaaa tctgggacaa aattattcca ggtaaaatgg atcgcttcat gcttgataac
    41821 actaaagttg accaagctta cacacttctt gcacaagttt acatcatgga tgacagcaag
    41881 acagttgaag cataccttga atcagttaac gcttcggtag ttgagtttgc tcgctttgaa
    41941 gttggtgaag gtatcgagaa agctgcaaac gacttcgaag ctgaagttgc agctacaatg
    42001 gcagcagcct tgaataacta ataatagaaa ggaagcaaat tgcttccttt tttgtatagg
    42061 gcttagattt ttcctgaaat tgttttttcc ccagtctcac tcgattagaa taattaaaac
    42121 aaaaagccct ataataaggg ctaagggcat ttaggagact atacttcaaa ttcat
//
LOCUS       DBERPV010000016        34629 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.16, whole genome shotgun sequence.
ACCESSION   DBERPV010000016 DBERPV010000000
VERSION     DBERPV010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 34629)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34629)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34629
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.16"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            60..929
                     /locus_tag="ACL8C7_001098"
     CDS             60..929
                     /locus_tag="ACL8C7_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HGS1395312.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            933..1889
                     /locus_tag="ACL8C7_001099"
     CDS             933..1889
                     /locus_tag="ACL8C7_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HGS1395313.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            1889..2653
                     /locus_tag="ACL8C7_001100"
     CDS             1889..2653
                     /locus_tag="ACL8C7_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1395314.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            2653..3363
                     /locus_tag="ACL8C7_001101"
     CDS             2653..3363
                     /locus_tag="ACL8C7_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1395315.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            3671..4327
                     /locus_tag="ACL8C7_001102"
     CDS             3671..4327
                     /locus_tag="ACL8C7_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HGS1395316.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDESIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            4435..5530
                     /gene="prfB"
                     /locus_tag="ACL8C7_001103"
     CDS             join(4435..4506,4508..5530)
                     /gene="prfB"
                     /locus_tag="ACL8C7_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HGS1395317.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            5548..6240
                     /gene="ftsE"
                     /locus_tag="ACL8C7_001104"
     CDS             5548..6240
                     /gene="ftsE"
                     /locus_tag="ACL8C7_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HGS1395318.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            6233..7159
                     /gene="ftsX"
                     /locus_tag="ACL8C7_001105"
     CDS             6233..7159
                     /gene="ftsX"
                     /locus_tag="ACL8C7_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HGS1395319.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            7445..9625
                     /locus_tag="ACL8C7_001106"
     CDS             7445..9625
                     /locus_tag="ACL8C7_001106"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HGS1395320.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            9677..10492
                     /locus_tag="ACL8C7_001107"
     CDS             9677..10492
                     /locus_tag="ACL8C7_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGS1395321.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAILNWK"
     gene            10632..11975
                     /locus_tag="ACL8C7_001108"
     CDS             10632..11975
                     /locus_tag="ACL8C7_001108"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGS1395322.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTSQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAIDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            12190..13380
                     /gene="metK"
                     /locus_tag="ACL8C7_001109"
     CDS             12190..13380
                     /gene="metK"
                     /locus_tag="ACL8C7_001109"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HGS1395323.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEVTNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAADLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            13933..14868
                     /locus_tag="ACL8C7_001110"
     CDS             13933..14868
                     /locus_tag="ACL8C7_001110"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HGS1395324.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            14902..15939
                     /gene="holA"
                     /locus_tag="ACL8C7_001111"
     CDS             14902..15939
                     /gene="holA"
                     /locus_tag="ACL8C7_001111"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HGS1395325.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            16112..16717
                     /gene="sodA"
                     /locus_tag="ACL8C7_001112"
     CDS             16112..16717
                     /gene="sodA"
                     /locus_tag="ACL8C7_001112"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase SodA"
                     /protein_id="HGS1395326.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            16875..17405
                     /locus_tag="ACL8C7_001113"
     CDS             16875..17405
                     /locus_tag="ACL8C7_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HGS1395327.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            17426..18511
                     /gene="rlmN"
                     /locus_tag="ACL8C7_001114"
     CDS             17426..18511
                     /gene="rlmN"
                     /locus_tag="ACL8C7_001114"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HGS1395328.1"
                     /translation="MKPSIHSLVHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERVSHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSISGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            18511..18993
                     /locus_tag="ACL8C7_001115"
     CDS             18511..18993
                     /locus_tag="ACL8C7_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGS1395329.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPDIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            18995..20536
                     /locus_tag="ACL8C7_001116"
     CDS             18995..20536
                     /locus_tag="ACL8C7_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGS1395330.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(20592..21395)
                     /locus_tag="ACL8C7_001117"
     CDS             complement(20592..21395)
                     /locus_tag="ACL8C7_001117"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGS1395331.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIGGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(21479..21700)
                     /locus_tag="ACL8C7_001118"
     CDS             complement(21479..21700)
                     /locus_tag="ACL8C7_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395332.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            complement(22179..22388)
                     /locus_tag="ACL8C7_001119"
     CDS             complement(22179..22388)
                     /locus_tag="ACL8C7_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395333.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSSKPVPKRNMDL
                     LADDSLARDIILLWRIQFGTFTTET"
     gene            22558..22830
                     /gene="rpsP"
                     /locus_tag="ACL8C7_001120"
     CDS             22558..22830
                     /gene="rpsP"
                     /locus_tag="ACL8C7_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HGS1395334.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            22850..23089
                     /gene="kphA"
                     /locus_tag="ACL8C7_001121"
     CDS             22850..23089
                     /gene="kphA"
                     /locus_tag="ACL8C7_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein KphA"
                     /protein_id="HGS1395335.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            23238..23562
                     /locus_tag="ACL8C7_001122"
                     /pseudo
     CDS             23238..23562
                     /locus_tag="ACL8C7_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000654120.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MazG nucleotide pyrophosphohydrolase
                     domain-containing protein"
     gene            23666..24454
                     /locus_tag="ACL8C7_001123"
     CDS             23666..24454
                     /locus_tag="ACL8C7_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGS1395336.1"
                     /translation="MKRFEVSTEIGSLSVAYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADVVYEALEELGISEYILCVHSWSGI
                     LACKLLEKPIKCQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            24485..25003
                     /gene="rimM"
                     /locus_tag="ACL8C7_001124"
     CDS             24485..25003
                     /gene="rimM"
                     /locus_tag="ACL8C7_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HGS1395337.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            24993..25712
                     /gene="trmD"
                     /locus_tag="ACL8C7_001125"
     CDS             24993..25712
                     /gene="trmD"
                     /locus_tag="ACL8C7_001125"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HGS1395338.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            25724..26062
                     /locus_tag="ACL8C7_001126"
     CDS             25724..26062
                     /locus_tag="ACL8C7_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP cone domain-containing protein"
                     /protein_id="HGS1395339.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(26092..26412)
                     /locus_tag="ACL8C7_001127"
     CDS             complement(26092..26412)
                     /locus_tag="ACL8C7_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395340.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            26510..26725
                     /locus_tag="ACL8C7_001128"
     CDS             26510..26725
                     /locus_tag="ACL8C7_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HGS1395341.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            complement(26722..26868)
                     /locus_tag="ACL8C7_001129"
     CDS             complement(26722..26868)
                     /locus_tag="ACL8C7_001129"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395342.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDETDEVSNHTYGKAKLTRFEEI
                     FEEY"
     gene            complement(26931..27467)
                     /locus_tag="ACL8C7_001130"
     CDS             complement(26931..27467)
                     /locus_tag="ACL8C7_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HGS1395343.1"
                     /translation="MKKAHVYAIPAIGAALIAALAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALAVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            complement(27664..29010)
                     /gene="gor"
                     /locus_tag="ACL8C7_001131"
     CDS             complement(27664..29010)
                     /gene="gor"
                     /locus_tag="ACL8C7_001131"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HGS1395344.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAQAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNRESYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTSSEEFVTMR"
     gene            29275..30474
                     /locus_tag="ACL8C7_001132"
     CDS             29275..30474
                     /locus_tag="ACL8C7_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HGS1395345.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVARADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            30458..31159
                     /locus_tag="ACL8C7_001133"
     CDS             30458..31159
                     /locus_tag="ACL8C7_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1395346.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            31161..32420
                     /locus_tag="ACL8C7_001134"
     CDS             31161..32420
                     /locus_tag="ACL8C7_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1395347.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYEFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            32544..34541
                     /gene="metG"
                     /locus_tag="ACL8C7_001135"
     CDS             32544..34541
                     /gene="metG"
                     /locus_tag="ACL8C7_001135"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HGS1395348.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
BASE COUNT        10491 a         6268 c         7608 g        10262 t
ORIGIN      
        1 agaacctatc aaaaagtgag ggaaaaccct cggaattata aatagaaaga gtgaatctta
       61 tgctccaaca actcgtaaat ggtttgattc taggtagtgt ttacgcgctg ttagccctag
      121 gatataccat ggtttacgga attatcaagc tcatcaactt cgcccatggt gatatttata
      181 tgatgggagc ctttatcggt tatttcttga tcaattcttt ccaaatgaat ttctttgtag
      241 cgcttattgt agctatgcta gcgacagcta ttcttggtgt cgtgattgag tttcttgctt
      301 accgaccttt gcgccactct actcgtattg ctgttttgat tacggctatt ggggtttctt
      361 tcctattgga gtatggaatg gtctatctgg ttggtgccaa tacccgtgcc ttccctcaag
      421 cgattcaaac agttcgatat gatttgggac caattagctt aacaaatgtg cagttaatga
      481 ttttggccat ttccttgatt ttgatgattt tgttacaagt cattgtccaa aagactaaga
      541 tggggaaagc catgcgtgca gtatcagtag atagcgacgc ggcacaattg atggggatca
      601 atgtaaaccg tacgattagc tttaccttcg ctttgggttc tgctcttgcg ggtgcggctg
      661 gtgttctgat tgctctttat tataactctc ttgagccttt gatgggggtt actccaggtc
      721 ttaaatcttt cgttgccgca gtacttggtg gtatcggaat tattcctggt gcggctcttg
      781 gtggctttgt gattggtcta ttggaaacct ttgcgacagc ctttgggatg tcagatttcc
      841 gtgatgccat tgtttatgga atcttgttgt tgatcttgat tgtccgccca gctggtatcc
      901 ttggtaagaa tgtgaaagag aaggtgtaaa cgatgaagga aaatttaaaa gttaatattc
      961 tatggttact ccttttgtta gctggctata gcttgattag tgtactggtt tcagtcggag
     1021 tacttaatct attctatgta cagattttac aacaaattgg aattaatatt attttggctg
     1081 ttggtctcaa cttaatcgtt ggtttttcag gacaattttc acttggtcat gctggtttca
     1141 tggcgattgg tgcctatgcc gcagctatta ttggttctaa atcaccaacc tacggtgcct
     1201 tctttggagc tatgcttgta ggggctttgc tttcaggagc agttgcctta cttgtcggca
     1261 ttccaacctt gcgcttgaag ggggactatc ttgcggtagc aactctgggt gtttctgaaa
     1321 ttatccgtat ctttatcatc aatggtggaa gtcttacaaa tggtgcggca ggtatcttag
     1381 ggattcctaa ctttacaact tggcaaatgg tttacttctt tgtcgtgatt acaaccattg
     1441 caaccttgaa cttcttgcgt agcccaattg gccgttcaac cctctctgtt cgtgaagatg
     1501 aaatcgctgc tgagtcagtt ggggttaata cgactaaaat taaaatcatc gcttttgtct
     1561 ttggtgccat tactgcaagt attgctgggt cacttcaggc aggatttatc gggtctgttg
     1621 taccgaaaga ttacaccttc atcaactcaa tcaacgtttt gattattgtt gtatttggtg
     1681 gactcggttc cattacaggt gcgattgttt cggctattgt tctgggaatt ttgaatatgc
     1741 ttctccaaga tgttgctagt gtgcgtatga ttatttacgc tttggccttg gtattggtaa
     1801 tgattttcag accaggtgga ctccttggaa cgtgggaact gagcctatca cgtttcttta
     1861 aaaaatctaa gaaggaggaa caaaactaat ggcattactt gaagtaaaac agttaaccaa
     1921 acattttggt ggtctaacag ctgttggaga tgtgactctt gaattgaacg aaggggaact
     1981 ggttggatta atcggtccaa acggagctgg gaaaaccacc cttttcaacc ttttgaccgg
     2041 tgtttatgaa ccaagcgagg gaacagtaac cctagatggt caccttttga atgggaaatc
     2101 accttataag attgcctctt tgggacttgg acgtactttc caaaatatcc gtctctttaa
     2161 agatttaaca gttttagata atgttttgat tgcttttgga aaccatcaca aacagcatgt
     2221 ttttactagt ttcttacgct taccagcttt ttacaagagt gaaaaagaat taaaggctaa
     2281 agctttggaa ttgttgaaaa tctttgattt agatggtgat gcagagactc ttgctaaaaa
     2341 tctttcctac ggacaacaac gtcgtttgga aattgttcgt gcccttgcta cggaacctaa
     2401 aattctcttc ttagatgaac cagcagcagg tatgaaccca caggaaacag ccgaattgac
     2461 tgagttaatt cgtcgtatca aagatgaatt taagattaca atcatgttga ttgaacacga
     2521 tatgaatctg gtcatggaag taacagaacg tatctacgta cttgaatatg gccgtttaat
     2581 tgctcaagga actccagacg aaattaagac caataaacgc gttatcgaag cttatctagg
     2641 aggtgaagcc taatgtctat gttaaaagtt gaaaatcttt ctgtgcatta cggtatgatc
     2701 caagcagtcc gtgatgtaag ctttgaagtt aatgaaggag aagttgtttc ccttatcggt
     2761 gccaacggtg caggtaagac aactattctt cgcaccttgt caggtttggt tcgaccaagt
     2821 tcaggaaaga ttgaattttt aggtcaagaa atccaaaaaa tgccagctca gaaaatcgtg
     2881 gcaggtggtc tttcacaagt tccagaagga cgccacgtct ttcctggctt gactgttatg
     2941 gaaaatcttg aaatgggagc tttcttaaag aaaaatcgtg aagaaaatca agctaacttg
     3001 aagaaggttt tctcacgctt tcctcgtctt gaagaacgga agaaccaaga tgcagctact
     3061 ctttcaggag gggaacaaca aatgcttgcc atgggacgcg ctcttatgtc aacaccaaaa
     3121 cttcttcttt tagatgaacc atcaatggga cttgccccaa tcttcatcca agagattttt
     3181 gatatcattc aagatattca gaagcaagga acaaccgtcc tcttgattga acaaaatgcc
     3241 aataaagcac tcgcaatctc tgaccgagga tatgtattgg aaacaggaaa aatcgtccta
     3301 tcagggacag gaaaagaact cgcttcatca gaagaagtca gaaaagcata tctaggtggc
     3361 taaaacaatc cagtggattg ttttagtcgg cagatgaaga ttacgaagta atcatcaata
     3421 tagtccgggg gaccttttta gtcggtggat agagattgca aacaaatatg catctacatt
     3481 gaaagcttaa tttctaataa ttgaaaaaat cgaatgaaaa atttcttacc ttcattcaca
     3541 gagctctatt tcagagctct ttttgctagc ttattcatac ttttttgaat ttcgaaaaag
     3601 aaatgtaagc gtttgataga tttacaaaaa gattgtataa tggggataag aatagaaaag
     3661 gagaagtctc atggcagtta aagattttat gacccgcaag gtagtttata ttagtccaga
     3721 tacaacagta tctcatgcag cagatttgat gagagagcaa ggtttgcacc gtctgcctgt
     3781 tatcgaaaat gatcaattag ttggtttggt gactgaggga accattgcac aagcaagtcc
     3841 atctaaagca acaagtcttt ctatctatga gatgaattat cttctgaata agacaaaagt
     3901 aaaagatgtc atgattcgcg atgttgtcac tgtctcaggc tatgctagtc tagaagatgc
     3961 aacttatctg atgttgaaaa ataagattgg tattctccct gtcgtagata accatcaagt
     4021 atacggagtt attactgacc gtgatgtttt ccaagccttt cttgaaattg caggttatgg
     4081 cgaagaaggg attcgtgtac gctttgttac agaagatgaa gttggtgttc ttggaaaaat
     4141 tgtttctttg attgtagaag aaaatttgaa tatctcccat acagtcaata ttccgcgtaa
     4201 ggatggtaag gtgattatcg aagtgcaaat cgatgaatca attgatttac cagccttgaa
     4261 agaaaaattt gaagcaaatg gtattcaagt ggaagaaatc gctcgcactt cagcaaaagt
     4321 cttgtaagaa gggaagtcca aaggcttctt ttttcatgaa aaggggatta gagcaaaaga
     4381 tggaaagaaa tgataaaata tgctataatg aaataatgta aaaaaggagt atttatggac
     4441 atttcagtaa ttcgtcagaa aattgacgca aatcgtgaaa aattagcttc tttcaggggg
     4501 tctctttgac ctcgaagggc tagaggaaga gattgccatc ttggaaaaca agatgacaga
     4561 acctgatttt tggaacgata atattgcggc ccaaaaaacg tcgcaagaat tgaatgaatt
     4621 aaaaaacact tacaatacct tccataagat ggaagagttg caggatgaag tcgaaatttt
     4681 attggatttt ttggctgaag acgagtcagt gcatgatgaa ctggtagcgc aattagccga
     4741 acttgataag ataatgacca gctacgagat gactctactc ttgtcagaac cttatgacca
     4801 caacaatgcc atcttggaaa tccatccagg ttctggtggt actgaggcgc aggactgggg
     4861 tgatatgttg cttcgtatgt atactcgtta tggtaatgct aaaggcttta aagtggaagt
     4921 gttggattac caagcaggtg atgaggctgg tattaagtcg gtaactttat catttgaagg
     4981 gcctaatgcc tatggtctcc tcaagtcaga aatgggtgtt caccgcttag tgcgaatctc
     5041 accatttgac tctgccaaac gtcgccatac ctctttcaca tctgtagaag tgatgccaga
     5101 attggatgat actattgaag tggaaatccg tgaagatgat atcaagatgg ataccttccg
     5161 ttcaggtggt gccggtggac aaaacgtcaa taaggtttca acaggtgtac gtttaaccca
     5221 cattccaact ggaattgttg tccaatcaac agtggatcgt acccagtatg gaaatagaga
     5281 tcgtgccatg aagatgttgc aggctaagct ctatcaaatg gagcaagata agaaggctgc
     5341 ggaggtagat tctctcaaag gtgagaaaaa ggagatcact tggggaagcc aaatccgttc
     5401 ttatgtcttc acgccttata ctatggtaaa agatcaccga actagctttg aggttgctca
     5461 ggtagataag gttatggatg gggacctaga tggttttatc gatgcttatc tcaagtggcg
     5521 aattagctaa gatagaaagg aactcacatg tcaattattg aaatgagaga tgtcgttaaa
     5581 aaatacgaca acggaacgac tgctctacgc ggtgtttcgg tcagcgttca accgggggaa
     5641 tttgcttaca tcgtaggacc ttcaggagca gggaagtcaa cttttattcg ttctctgtat
     5701 cgtgaagtaa aaatcgataa aggaagtcta tcagttgctg gttttaatct ggttaagatc
     5761 aaaaagaaag atgtcccgct tctacgtcgt agtgttgggg ttgtcttcca agattataaa
     5821 ttgttaccaa agaaaactgt ctatgaaaat attgcttacg ctatggaagt aatcggggaa
     5881 aatcgccgta atatcaaaag acgagtgatg gaagttttgg acttggttgg attgaagcat
     5941 aaggttcgtt ctttcccaaa tgaactctca ggtggggagc aacagcgaat tgcgattgcg
     6001 cgtgcaattg taaataatcc caaagtattg atagctgatg agccaacagg aaatctggat
     6061 ccggataatt catgggaaat tatgaatctc ttggaacgga ttaacctaca aggaacaact
     6121 attttgatgg cgactcataa tagccagatt gtaaatacct tgcgccaccg tgtcattgcc
     6181 attgaaaatg gccgtgtcgt tcgtgacgaa tcaaaaggag agtatggata cgatgattag
     6241 tagatttttt cgccatttat ttgaagcctt aaaaagtttg aaacgaaatg gttggatgac
     6301 agtagctgct gtcagttcag tcatgattac tttgaccttg gtggcaatat ttgcatctgt
     6361 tattttcaat acagcgaaac tagctacaga tattgaaaat aatgtccgtg tagtagttta
     6421 tatccgaaag gatgtggaag ataatagtca gacaattgaa aaagaaggtc aaactgttac
     6481 aaataatgac taccacaagg tatatgattc tttgaagaac atgtctacgg ttaaaagtgt
     6541 taccttttca agtaaagaag aacaatatga aaaattaacc gagataatgg gagataactg
     6601 gaaaatcttt gaaggagatg ccaatcctct ctatgatgcc tatattgtag aggcaaacac
     6661 tccaaatgat gtaaaaacta tagccgaaga tgctaaaaaa attgaaggtg tctctgaggt
     6721 tcaagatggc ggtgccaata cagaaagact cttcaagtta gcttcattta tccgtgtttg
     6781 gggactaggg attgctgctt tgttaatttt tatcgcagtt tttttgattt caaataccat
     6841 tcgtattacc attatttccc gcagtcgcga aattcaaatc atgcgcttgg tcggagctaa
     6901 aaacagttat atccgtggac cgttcttgtt agaaggagcc tttatcggtt tattgggagc
     6961 tatcgcacca tctgttttgg tctttattgt ttatcaaatt gtttaccaat ctgtcaacaa
     7021 atcgttggta gggcaaaatc tatccatgat tagtccagat ttatttagtc cgttgatgat
     7081 tgccctacta tttgtgattg gggttttcat tggttcattg ggatcaggaa tatccatgcg
     7141 ccgattcttg aagatttagg taaaatagct gcttttatga ggagattgca aaatctcctt
     7201 ttttgctaca agagtttttg aaaagagatg cgcagaagaa aagagcttcc aaagaagtcc
     7261 cccagagaag acttcttgat ggctaatttg aacttgaaat ttggcgcact agaaattttt
     7321 tagaaaaaag tgtaattttt ttataaaagc ctttacaaaa aaaattaaag tggtataatt
     7381 aaatcataga aagtgcaaac gttttcgtaa aacgtttgcc taaataaaaa taaaggagat
     7441 ttgaatgatg aaagatacat tcaaaaatgt cttgtctttc gaattttggc aaaaattcgg
     7501 taaggctttg atggtagtta tcgcggttat gccggctgct ggtttgatga tttcaatcgg
     7561 taagtctatc gtgatgatta acccaacctt tgcaccactt gtcatcacag gtggaattct
     7621 tgagcaaatc ggttgggggg ttatcggtaa ccttcacatt ttgtttgccc tagccattgg
     7681 aggaagctgg gctaaagaac gtgctggtgg tgctttcgcc gctggtcttg ccttcatctt
     7741 gattaaccgt atcactggta caatctttgg tgtatcaggc gatatgttga aaaatccaga
     7801 tgctatggta actactttct ttggtggttc aatcaaagtt gctgattact ttatcagtgt
     7861 tcttgaagct ccagccttga acatgggggt attcgtaggg attatctcag gttttgtagg
     7921 ggcaactgct tacaacaaat actacaactt ccgtaaactt cctgatgcac tttcattctt
     7981 caacgggaaa cgtttcgtac catttgtagt tattcttcgt tcagcaatcg ctgcaattct
     8041 acttgctgct ttctggccag tagttcaaac aggtatcaat aatttcggta tctggattgc
     8101 caactcacaa gaaactgctc caattcttgc accattcttg tatggtactt tggaacgttt
     8161 gctcttgcca tttggtcttc accacatgtt gactatccca atgaactaca cagctcttgg
     8221 tggtacttat gacattttaa ctggtgcagc taaaggtact caagtattcg gtcaagaccc
     8281 actatggctt gcatgggtaa cagaccttgt aaaccttaaa ggtactgatg ctagtcaata
     8341 ccaacacttg ttagatacag tacatccagc tcgtttcaaa gttggacaaa tgatcggttc
     8401 attcggtatc ttgatgggtg tgattgttgc tatctaccgt aatgttgatg ctgacaagaa
     8461 acataaatac aaaggtatga tgattgcaac agctcttgca acattcttga caggggttac
     8521 tgaaccaatc gaatacatgt tcatgttcat cgcaacacct atgtatcttg tttactcact
     8581 tgttcaaggt gctgccttcg ctatggctga cgtcgtaaac ctacgtatgc actcattcgg
     8641 ttcaatcgag ttcttgactc gtacacctat tgcaatcagt gctggtattg gtatggatat
     8701 cgttaacttc gtttgggtaa ctgttctctt tgctgtaatc atgtacttta tcgcaaactt
     8761 catgattcaa aaattcaact acgcaactcc agggcgcaac ggaaactacg aaactgctga
     8821 aggttcagaa gaaaccagca gcgaagtgaa agttgcagca ggttctcaag ctgtaaacat
     8881 tatcaacctt cttggtggac gtgtaaacat cgttgatgtt gatgcatgta tgactcgtct
     8941 tcgtgtaact gttaaagatg cagataaagt aggaaatgca gagcaatgga aagcagaagg
     9001 agctatgggt cttgtgatga aaggacaagg ggttcaagct atctacggtc caaaagctga
     9061 catattgaaa tctgatatcc aagatatcct tgattcaggt gaaatcattc ctgaaactct
     9121 tccaagccaa atgactgaag cacaacaaaa cactgttcac ttcaaagatc ttactgagga
     9181 agtttattca gtagcagacg gtcaagttgt tggtttggaa caagtaaagg atccagtatt
     9241 tgctcaaaaa atgatgggtg atggatttgc agtagaacct gcaaatggaa acattgtatc
     9301 tccagtttca ggtactgtgt caagcatctt cccaacaaaa catgcttttg gtattgtgac
     9361 ggaagcaggt cttgaagtat tggttcacat tggtttggac acagtaagtc ttgaaggtaa
     9421 accatttaca gttcatgttg ctgaaggaca aaaagttgca gcaggagatc tccttgtcac
     9481 agctgacttg gatgctatcc gtgcagcagg acgtgaaact tcaacagtag ttgtcttcac
     9541 aaatggtgat gcaattaaat cagttaaatt agaaaaaaca ggttctcttg cagctaaaac
     9601 agcagttgct aaagtagaat tgtaatatac ttgaggttgg aagctgtatt ccaacctctt
     9661 attttgggag aaaagaatga aatttttaac actcaatact cacagttgga tggagaaaga
     9721 agcagaggaa aaattccaga ttttgcttga agatattctt gaaaaggact atgatttgat
     9781 ttgtttccaa gaaatcaatc aggagatgac ctcgtcagag gtggaggtta atgaccttta
     9841 tcaagctttg ccagcagctg agcctattca ccaagaccat tatgttagac tcttggttga
     9901 aaagttgtta gagcaaggga aaaattacta ctggacctgg gcttataacc atatcggcta
     9961 tgaccgctac cacgaaggtg tggctatctt gtctaaaaca cctattgaag ccagagaaat
    10021 tttggtttca gatgtggatg atccaacaga ctatcatact cgccgtgttg ccctagctga
    10081 aactgtagtc gatggcaagg agctagcagt tgccagtgtt catctctctt ggtgggataa
    10141 aggtttccaa gaagaatggg cacgatttga ggctgtcttg aaaaaattga acaagccact
    10201 tttactagct ggagatttta acaacccagc aggtcaggaa ggttaccaag ctattttagc
    10261 tagtccatta ggcttacaag acgcatttga agttgctcaa gagaaaagtg gtagctatac
    10321 tgttccgcct gaaattgatg gctggaaagg gaacactgaa ccccttcgaa tcgattatgt
    10381 ctttactacc aaagagttag cggtggaaaa tttacatgtc gtatttgatg gtaacaagag
    10441 tccacaagtg agtgatcact atggcttgaa tgctatatta aactggaaat aataactgaa
    10501 aagaggttgg aactataaaa ttccagcctt ttcttactag agaagctact ggaaatagcc
    10561 taaataagtg agactactgt aatggaataa aatatggtat aattgataag atagatagaa
    10621 tcgaggatgt tatgtcattt acgaaatttc aatttaaaaa ctatattaga gaagccttga
    10681 aggagttaaa atttacaact ccaacagagg tgcaagacaa gttgattcct attgttttgg
    10741 caggtcgtga cctagtagga gaatcaaaaa caggttcagg taagactcat actttcttgt
    10801 taccgatttt ccagcaatta gatgaagcta gcgatagtgt acaagcagtg attactgcac
    10861 cgagtcgtga gttggctact caaatttacc aagtagcgcg tcagatttca gctcactcag
    10921 atgtcgaagt tcgtgtggtt aattatgtgg gtggtacgga taaggctcgc cagattgaga
    10981 aattggcaag caatcagcct catattgtta ttggaacacc aggccgtatc tacgacttgg
    11041 ttaaatctgg tgatttagct attcataaag ccaagacatt tgttgttgat gaagcagata
    11101 tgaccttgga tatgggattc ttggaaactg ttgataagat tgctggcagt cttccaaaag
    11161 acttgcaatt catggtcttc tcagcgacta tcccacaaaa actgcaacca ttcttgaaaa
    11221 aatacttatc aaatcctgtt atggagaaaa ttaagaccaa aacggttatt tctgacacca
    11281 ttgataattg gttgatttcg accaagggac atgataagaa tgctcaaatt taccagttga
    11341 ctcagttgat gcagccgtat ttggcaatga tttttgttaa cactaaaacg cgtgctgatg
    11401 aattgcattc atatctgact tctcaaggtt tgaaggttgc aaaaatccat ggcgatattg
    11461 cccctcgtga acgcaagcga atcatgaatc aggtgcaaaa tctggatttt gagtatattg
    11521 tcgcaacaga tttagcagcg cgtgggattg acattgaagg tgtcagccat gtcatcaatg
    11581 atgccattcc gcaagactta tctttttttg ttcaccgtgt tggtcgtact ggacgaaatg
    11641 gcctaccagg tacagctatt accctttatc agccaagtga tgactcggat atccgtgagt
    11701 tggagaaatt gggaatcaag tttagtccta agatggtcaa agacggggaa tttcaagata
    11761 cctatgaccg tgatcgtcgt gccaaccgtg agaaaaaaca agataaactt gatatcgaaa
    11821 tgattggttt ggttaaaaag aaaaagaaaa aagtcaaacc gggttataag aagaaaattc
    11881 aatgggcgat tgatgaaaag cgccgtaaaa ccaagcgtgc tgaaaatcgc gctcgcggcc
    11941 gtgcagagcg taaagctaaa cgccaaacat tttaatagaa attgttggag tattgagctc
    12001 caactttttg ctttatgaga acgaactatc taaaccgaaa cactacatta aagactgcaa
    12061 attgcgatta aaaatggtat aatgataaag ttatatagtc ccgataagat ggtaggtatt
    12121 tattacgaag agttttccta tcagtacttt gtaactctat aacaatattt tttaaggggg
    12181 gacattttta tgtcagagcg taaattattc acgtctgaat ctgtatctga ggggcatccg
    12241 gataagattg cagaccaaat ttcagatgcg attttggatg ctattttagc aaaggatcca
    12301 gaggcgcacg ttgctgctga aacagctgta tatactggtt ctgtccacgt ttttggtgaa
    12361 atttctacaa atgcctatgt ggatattaac cgtgtggttc gtgataccat tgcagagatt
    12421 ggttatacca atacagaata tggattttct gctgagacgg tgggagtaca cccatctttg
    12481 gtggaacaat ctcctgacat cgctcaaggt gttaacgaag ccttggaggt tcgtggaaat
    12541 gctgatcaag atccactgga cttgattgga gcaggtgacc aagggctcat gtttggattt
    12601 gcagtagatg aaacagaaga gctcatgcca ttgccaattg cacttagtca taaattggtt
    12661 cgtcgtctgg cagaacttcg taagtctgga gaaattagct atctccgtcc agatgcaaaa
    12721 tcacaagtta cagttgagta cgatgaaaat gaccgtccgg tacgtgtaga tacagtcgtt
    12781 atttctactc agcatgatcc agaggtcact aatgaacaaa tccatcaaga tgtgattgac
    12841 aaggtcatca aagaagttat tccatcttct tatcttgatg ataagacaaa attctttatc
    12901 aatccgacag gtcgttttgt aatcggtggt cctcaagggg actcaggttt gactggtcgt
    12961 aagattattg tagatactta tggtggctac tctcgtcatg gtggtggtgc cttctctggt
    13021 aaagatgcga ctaaggtgga tcgttcagcc tcttatgcgg ctcgctatat tgccaagaat
    13081 atcgttgcag cagaccttgc taagaaggca gaagtgcagt tggcctatgc tatcggtgtt
    13141 gcgcaacctg tttctgttcg tatcgatact ttcggtacag gaacagtagc tgaaagtcaa
    13201 cttgaaaaag cggctcgtca aatctttgac cttcgccctg cagggattat acaaatgctg
    13261 gaccttaagc gtccaattta ccgtcaaaca tcggcttacg gtcacatggg acgtacagat
    13321 attgatcttc catgggaacg tttggataag gtagatgctt tgaaagaagc agtaaaataa
    13381 gattttaaga ggggaacgtc ctctcttttt tatagttttt aactatactg ggatactgtt
    13441 ctgaaaatcc attttgtgaa agtagagatt tacatgtata gtagattgaa actagaatag
    13501 tacacctcaa cttctaaaac attgttagaa atcgatttga ctgtcctgat tgatttctcc
    13561 tgttcttgtt tcattttact atatttcttt aaaaatgata aaggttgaga tttctcctcg
    13621 taatagataa tcatggggat atttcaatcc aaagttttat tcgttatcac ttgactattg
    13681 caaggttttc tagagcaaca gagtcatgga atggactcat ggttgagatt tctccttgtt
    13741 gcttggactt cattcaaaag tctgttaccc aagccttgtt caaacttcca atacactagc
    13801 tgtttccata gcatgacttc tgtactagac tttcttttcc gaataaatag atagaaccac
    13861 agaatctagt aaacctagaa ttaaaattat ggtataatat tagcaataaa agaaatctgg
    13921 aggattagaa tcatggtatc aacgaaaaca caaattgctg gttttgagtt tgacaattgc
    13981 ttgatgaatg cagcaggtgt ggcttgtatg acgatagagg agttagaaga ggtcaaaaac
    14041 tcagcggcag gaacctttgt tactaagaca gcgaccttgg acttccgtca ggggaatcct
    14101 gagccacgct accaagatgt tccacttggt tccatcaact ctatgggctt gccaaataat
    14161 ggcttagact attatttgga ttatctttta gatttgcagg aaaaagagtc gaaccgaact
    14221 ttcttcttat ctctggtcgg catgtctcca gaggaaaccc atactatttt gaaaaaagtc
    14281 caagagagtg attttcgtgg tctgactgag ctaaatcttt cctgtccaaa tgttccaggt
    14341 aaacctcaga ttgcctatga ttttgagaca acagaccgga ttttggcaga agtgtttgct
    14401 tacttcacca aacctcttgg aattaaattg ccaccttatt ttgatattgt tcactttgat
    14461 caagcggcag ctattttcaa caaatatccg ctcaagtttg tcaactgcgt taactctatc
    14521 ggaaacggcc tctatataga agacgaatct gtcgttattc ggcctaagaa tggttttggt
    14581 ggaattggtg gagaatacat caaaccgact gctctagcca atgttcacgc cttttatcaa
    14641 cgtttaaatc ctcaaatcca aattatcgga acaggtggcg ttctgactgg tcgagatgcc
    14701 tttgaacaca tcctctgtgg agcaagtatg gtgcaggtgg gaacgaccct tcacaaagaa
    14761 ggtgtcagtg cttttgaccg cattaccaat gaactgaaag caatcatggt ggaaaaaggc
    14821 tacgagagct tagaagattt ccgtgggaaa ttgcgctata ttgactaaat taaatcgaaa
    14881 aatctgaaga aaggagagac gatgctagcc attgaagaaa gtcagaagtt gactttatca
    14941 aatttaccga gcctgagcct atttacaggg acagatcagg gtcagtttga agtgatgaag
    15001 agtcaagtgt tgaaacagat tgggtatgat tctgctgacc tcaactttgc ctactttgat
    15061 atgaaagaag tagtttacaa ggatgtggaa ctggagttgg tcagccttcc tttctttgcg
    15121 gatgagaaaa tcgtgatatt agattatttt atggatatca cgactgctaa gaaacgcttt
    15181 ttgacagatg atgagcttaa gtcatttgag gaataccttg acaatccttc tccaacaacc
    15241 aagttgataa tctttgcaga aggaaagctg gatagcaaaa gacggttagt caaattactt
    15301 aagcgtgatg ccaaggtctt cgatgcagta gaagtaaaag aacaagaatt gcgccagtat
    15361 ttccaaaagt ggagtcagaa acaaggtctg cagtttacca atcattcttt tgaaaatctc
    15421 ctcatcaagt cggggtttca atttagcgaa atccagaaaa atcttctctt tttacagtcc
    15481 tataaggcgg attctgttat cgaggaagag gatattgtta acgcaattcc caagaccttg
    15541 caggacaata tttttgattt aactcagttt attctgacta aaaagatgga tcaggcgcgc
    15601 gatttggtga gagacttgac cttgcaaggg gaagatgaaa tcaaactgat tgcagtcatg
    15661 ctgggacaat ttcggacttt tactcaggtg aagattttgg cggagtctgg ccaaacagaa
    15721 tcgcagattg caagtagttt aggtagttat ctgggacgta acccaaatcc ttatcaaatc
    15781 aagtttgcat taagagattc gagaggactt tctttgagct ttctgaagca agctatttcc
    15841 tatttgattg agacagacta tcagattaag acaggtcttt atgaaaaagg tttccttttt
    15901 gaaaaggcac tcttacagat tgctagtcag gtcaattgac atttgttgaa actacaaccc
    15961 gcgtcaggat tatcttgtcg tgggtttctt gctgatttgc ttattttatt agaaagtatg
    16021 tcagtgattt ccttatctat aagcaaaaaa cttgaaaaaa gtgaatgttt gcgttatcat
    16081 tttcatatag aaagaaaaag aggtattaca gatggctatt atcttaccag aacttccata
    16141 tgcatacgac gctttggaac catacatcga tgcggaaaca atgcatttgc accatgacaa
    16201 acaccatcaa acttatgtca acaatgccaa tgcagcttta gaaaaacacc ctgaaatcgg
    16261 tgaagacctt gaagccttgc ttgctgatgt agaatctatc ccagctgata tccgtcaagc
    16321 acttatcaac aatggtggcg gacacttgaa ccacgctctt ttctgggaat tgatgactcc
    16381 cgagaaaaca gctccttcag cagaactggc agcagcaatc gatgcaacat ttggttcatt
    16441 tgaagaattc caagcagcct tcactgcagc agcaacaact cgttttggtt caggttgggc
    16501 atggttggtt gtcaacaaag aagggaaact tgaagtgact tcaacagcaa accaagacac
    16561 accaatctca gaaggtaaaa aaccaatctt gggcttggac gtttgggaac atgcttacta
    16621 cgtgaaatac cgcaacgtgc gtcctgacta catcaaagct ttcttttcag taatcaactg
    16681 gaataaagta gatgaattgt acgcagctgc taaataatga tagttggagg gaagaattgt
    16741 tcttctcttt tttaggttat aagattctgg tctgacaaaa tcgttagact tttttcattt
    16801 tttatgagaa acgtgctaac tgctagaaat tatggtagaa taaagtatta agtaatcgtg
    16861 gaaaaaggat atctatgcga aaagaaattg cacctgaatt atacaactat aacaagtttc
    16921 ctggtccgga gttccattta cacggggaca aggtcgaaac ggaagggata gctttttcct
    16981 tggttgaaaa tatcaaggat gcctttgatg tgacgacttt taatcagcgt ttttcagaag
    17041 tcttaaccaa gtttgattat atcgtggggg actggagcaa cgaacagctt cgcctacgag
    17101 gtttttacaa ggatgaccga acagaagaaa aacttgaaaa aatcagtcgt ttacaagact
    17161 accttttaga gtattgtagt tatggttgtg cctattttgt cttagaaaat gaagccccta
    17221 agcgagcatc atttgacaag aaaatgcgta agacggaaga agaaacacct tctagaaaag
    17281 gaaagaaacc gactcaaact aaacgaaagt cgaatgcaga taagaaaaat agacgtcgtc
    17341 agaaagacca gcattctcag aaagaggaca aggaacaacg tcattttgtc attcgtcaga
    17401 agtgagtaga gaataaggag aagaaatgaa accctcaatt catagtttgg tacatcaaac
    17461 catgcaggaa tgggtattgg agcagggaga aaagaaattc cgtgcagatc aaatctggga
    17521 atggctctac cgtaaacgtg tgcagtcatt tgaagaaatg accaaccttt ccaaggattt
    17581 gattgctaag ctcaatgacc agtttgtggt caatcccttg aaacaacgta ttgtgcaaga
    17641 gtctgctgat ggtacagtca aatatctctt tgaattgcct gacggtatgt taattgagac
    17701 tgtactcatg cgtcaacact atggtttatc tgtctgtgtg accactcagg tcggctgtaa
    17761 tatcggttgt accttctgcg cctctggttt gattaagaag caacgtgacc tcaataacgg
    17821 tgaaatcgta gcgcaaatca tgctggttca gaaatacttt gatgagcgtg gtcaggatga
    17881 acgcgtcagc catatcgttg tcatgggaat cggtgagccc tttgataatt acaacaatgt
    17941 cttgaatttc tttcgtacta tcaatgatga taaaggaatg gctatcggtg ctcgtcacat
    18001 cacggtttca atctcaggtt tggctcataa aattcgtgac tttgctgatg aaggggttca
    18061 ggtcaatctt gccgtgtctc ttcacgcacc caacaatgaa cttcgttcaa gtatcatgaa
    18121 gattaaccgt gcctttccga ttgaaaaact ctttgctgct attgaatact acattgagac
    18181 aacaaaccgt cgtgtaacct ttgaatatat catgcttaat gaagtcaacg acggtgtaga
    18241 acaagccttg gaattggctg aattgctcaa gaacatcaag aaattgtctt atgtaaactt
    18301 gattccttat aacccagtta gtgagcatga ccaatatagc cgtagtccca aagagcgcgt
    18361 gttggctttc tatgatacgc ttaagaaaaa aggggtcaac tgtgtggttc gtcaagagca
    18421 tggtacagat attgacgcag cttgtggaca attgcgctct aacacaatga aacgtgaccg
    18481 ccagaaggca gtcgcagcgg taaatcctta atgatgaaga agacttataa tcatattttg
    18541 gtctggggag tcattttcta tagcatttgc attgtctgtt tttgctttac tcctcaagaa
    18601 caatctaccg tgggagtggg aactccagat attcagcatc ttggacgcct ggtttttctt
    18661 ttgactcctt tcaattctct ctggaaactg ggcgaagtga gtgacattgg acaattatgt
    18721 tggatttttt tacaaaatat cctcaatgtc ttcttgtttt ttcctctgat tttccaactc
    18781 ctttatctat ttccaaattt gcggaaaaca aaaaaggtcc ttctttttag ttttcttgtg
    18841 agtcttggaa tcgagtgtac gcaattaatc ttggactttt tctttgattt caatcgcgtc
    18901 tttgagattg atgatttgtg gaccaacact ttgggtggct atctggcttg gctcctttat
    18961 aaacgattac ataaaaacaa gataaggaat taaaatgagt attttagaag ttaaaaatct
    19021 gagtcacggt tttggtgacc gtgcaatttt tgaagatgtg tccttccgtc tcctcaaggg
    19081 agaacatatc ggcctggtcg gtgccaatgg tgaaggaaaa tcaaccttta tgagtatcgt
    19141 gactggtaaa atgctgccag atgaaggaaa ggttgagtgg tccaaatatg tgacggctgg
    19201 ttacttggat cagcactctg tccttgctga aagacagtcg gtgcgtgatg ttctccgtac
    19261 ggcttttgat gagcttttca aagctgaagc tcgtatcaat gacctctata tgaaaatggc
    19321 tgaagacggc gcggatgttg atgctctcat ggaagaagta ggagaacttc aagaccgtct
    19381 ggagagtcgt gatttctata ccttggatgc taagattgac gaagtagcgc gtgctcttgg
    19441 tgttatggac tttggcatgg atacggatgt aacttctttg tcaggtgggc aaagaaccaa
    19501 ggtgcttttg gcaaaacttc tccttgaaaa gcctgatatt ttgctgttgg acgagccgac
    19561 caactacttg gatgctgagc atattgattg gctcaagcgc tatctccaaa actatgagaa
    19621 tgcctttgtt cttatttcgc acgatattcc attcctcaat gacgttatta atattgtcta
    19681 tcatgtggaa aatcaacagc tgacgcgtta ctctggtgac tactaccagt tccaagaagt
    19741 ttatgctatg aagaaatctc agctagaggc agcctacgaa cgccagcaga aagagattgc
    19801 agacctcaag gactttgtgg ctcgtaataa agcccgtgtt gcaactcgta atatggctat
    19861 gtctcgtcaa aagaaattgg ataagatgga tattatcgaa ctccaaagtg agaaaccaaa
    19921 accatccttt gatttcaaac cagctcgtac accagggcgc tttatcttcc aagccaagaa
    19981 cttgcaaatt ggttacgacc gtcctcttac taagccttta aatcttacct tcgaacgcaa
    20041 tcaaaaggtt gcgattattg gtgctaatgg tattggaaaa acaactctct tgaagagtct
    20101 cttaggcatt atctcgccaa tcgctgggga agtggagcgt ggagattatt tagaacttgg
    20161 ttattttgag caggaagtag aaggcggtaa tcgccaaact cctcttgaag ctgtctggaa
    20221 tgcctttcct gcccttaatc aagcagaagt ccgtgcagcc cttgcccgtt gtggtttgac
    20281 aaccaaacat attgaaagcc agattcaagt attatcaggg ggagagcaag ccaaggttcg
    20341 tttctgtctc ttgatgaatc gtgaaaacaa cgttttagtg ctggacgagc cgaccaacca
    20401 tttggatgtg gatgcaaagg atgagctcaa acgcgctctc aaagaataca ggggatctat
    20461 ccttatggtc tgccacgagc cagactttta tgaaggttgg atagaccaaa tatgggattt
    20521 taataattta acttaagaat gagagtaaaa gaaatacagt accgaatgtg gatactgtat
    20581 ttttttggtt tttaagattt aaaatcgtag tctttcacca cttcgatgct gtcgattgtg
    20641 atagcagtag ttggcttgtc tttttcatct ttttcggctt tagcaatctt atccacaaca
    20701 tccataccgc caatcacttg accaaagact gggtgtttgc catctagact agggtttcca
    20761 ccttctttgt aggcttcgat aattttctgt ggatacttgc ttgtagggag tttagaagag
    20821 gtatctgtag agttttggtt gatgaagaac tggctgccat tggtgtttgg ttgaccagta
    20881 ttagccatag caagagcacc gcggatgtta tacaaataag gagtaatctc gttcttgaaa
    20941 ccagttcctt tgtctttagt cttatccttg tcatgccaga tggactgacc acctgtaccg
    21001 tccccttttg gatctccagt ttggaccata aagccatcga tgacacggtg gaaggtaata
    21061 ccgttatagt agccttcttt ggcatgagtg aggaaatttt caaccgctag aggagcgagt
    21121 ttagggaaga gtttaatgcg aatatcacct tggcttgtgt ggagaatcac ttcggcttca
    21181 tcttcagcaa cttccttaga tagttgtggg aaattggcgt tttcgtttgt taatgcatcg
    21241 tttaactcct tggcagattg ggcagctact ttggaacttt cttcagcagc aagactggaa
    21301 tcaacataat catcaccacg cagactgcgt tggacgctgc tacacccagc tagggctaca
    21361 gtagacagta aaagaagggt tgctagtttt ttcattctga tcctctcaaa aattcattta
    21421 taaccattgt accctaaaag gaagtggatt tcaaatatta gtagtttaca gaactggctt
    21481 agataatagt tgggatttca tcatcatctt gaaaatcttc aacttcttca acttcttccc
    21541 cagtaaatgg tttctgaaaa gaacttagta taaaacgggc aattggttca acaattagga
    21601 aatttagagg aagagctgca ataaagttta cgaaccaggc gcttagatag gtattgggtg
    21661 tgatagcaat gccattgtaa aaaagtccat agaaggacat gaaagtgacc agctaattct
    21721 tcttctgaaa aatgctcatg aagagcttga tccaggttgc aagatttcat tttagaaagt
    21781 ccagtaactc ccttcttctt caggatattc tttttcatgg tagtatttag atggtcaagt
    21841 gagtcaaaag aagtttcgac aagagcatac cctttttcta ccagagtttt tagatgtttt
    21901 ggggcatcaa tgccataagt gtactcaaag tatttaggga accagatctt aagaaagctc
    21961 gtaaagctag ccagttctct aaacgttaag aactagctac aatacagcat ttacaacact
    22021 tcatggttca caccatgggg tgttttttta tgattttaag caaaattcac acttaattga
    22081 aagttattta aattagatga aaatttattt tttgaaaaag tgggaaaaca ttgattctaa
    22141 gcgaattttg aatcatattc gaatgggagt ttttaaaatc atgtttcagt ggtaaaagta
    22201 ccaaactgga ttctccatag taaaatgata tctcttgcta gtgaatcatc tgctaataag
    22261 tccatatttc gcttgggaac gggtttggaa cttagaagcc aagtatccaa ctctcgttca
    22321 ggcgatatga agggtttgac ttggtgttct ttataaaatt tttctaaaat agtattcacg
    22381 gatagcatct ttcaaacatt tatttcctat tctaacaaat ttctaaatgc tttaagaaat
    22441 ttatagtctg tcaagttttt ttcttgacac ctgccagaaa tctgctataa tagaacatgt
    22501 gctaaatagc tcagctattt caccgaaata aaaaattaaa gaaatgagac tttaaaaatg
    22561 gcagttaaaa tccgtttgac tcgtatgggt tctaagaaaa aacctttcta ccgtatcaac
    22621 gtagcagatt cacgttcacc acgtgacgga cgtttcatcg aaacagttgg aacttacaac
    22681 ccacttgttg ctgaaaacca agtaactttg aaagaagacc gcgttcttgc atggttggct
    22741 aatggagctc aaccttcaga cacagtacgt aacatccttt caaaagaagg cgtattgaaa
    22801 aaattccacg attctaaatt ctcaaaataa gtttaaagta ggttgacaga tggatacgat
    22861 tgaaaatctc attattgcga ttgtgaaacc cttaatttca caaccagatg ccttaactat
    22921 caagattgag gatacaccag aatttttgga atatcatttg aatcttgatc aaagcgatgt
    22981 gggtcgtgta atcggtcgta agggtcgcac tatttctgcg ataagaacga ttgtctactc
    23041 tgtcccaact gaatacaaaa aagtaagaat cgttattgac gaaaaataag aagggcggga
    23101 cggatgtctc gcttttttgt gtggaataga agatatagta aaatgaaata ataacaggac
    23161 aaatcgatca ggacagtcaa atcgatttct aacaatgttt tagaagtaaa ggtgtactat
    23221 tctagtttca atatactata aaagattgaa cgtttaggca attccaagac tacttactcg
    23281 aacattaaca gcagtctcgg actgatgaag gtctctttat gaagttagtg gaggaagtcg
    23341 gagaagtagc cgaggttttg aataggcgct ctggtcgaaa agaagggata ggattcgaac
    23401 gaggaacttg ccagagaact ggctgatatc atttactaca ccgtcgcaat cgtagctatt
    23461 aatcatattg accttaccaa gactgtcttt gagaaagaca aaaccgcagc cgttaattac
    23521 caacataaac ataatttgga aggattattg aagggaaagt agagatgttg tccccttcct
    23581 ccaacttgag aaaatccttg gaacgtgata aaataaagga taaggatttt taataattca
    23641 ttatatagaa tgagtggatt tctttatgaa gaggtttgaa gtatctacag aaattggtag
    23701 tctctctgtt gcttatcaaa agcaaaagaa agtgctagtt tgtctaaacg gagcaggttt
    23761 gctaccaagt tatgaaaatt tttcacttat acttgaaaaa cctcctccta caattggtta
    23821 tttgacaatt gattttccga acacaggtag gagtccgatt catgaccaag ctggaaaaaa
    23881 tctagataat cttgcagatg tggtttatga agcacttgaa gaattaggga tttctgaata
    23941 tatactttgt gtacatagtt ggagtggaat tttagcttgc aaattactcg agaaaccaat
    24001 taagtgtcag actttagtag caattgaacc gacaactaaa aaagtcatgt ttgctgattt
    24061 ttcagaaaat ccttatccag aaatggaaga gcagatgagg ctgattgacg agtgtggtcc
    24121 tgaactttat tttaagaact taactcaagc aacatttagt cctgaaacga ataaaaaaat
    24181 ctgggaatta atgcaagaaa aaggcttaga gttggaaaat caagatccag aatttcagat
    24241 atctggagag attactgagg aagattttga gaatttgtcg atagaatctc atgtccctgt
    24301 atttattttt tgtcagactt atagagaaaa agagtacaga gaatcagaat attggacttc
    24361 caatactaaa ctcattttag gagggaatca ccattattta caatggtcag aatcggaaaa
    24421 aattgcggct attattcgag aattgtcaga ataagatgga aaaaaggaga ttacaggaga
    24481 caagatgaac tactttaatg ttgggaaaat cgttaatacg cagggattac agggtgagat
    24541 gcgagtcttg tctgtgacgg attttgcaga agaacggttt aaaaaaggag ctgagctggc
    24601 tttgtttgat gaaaaagatc agtttgtcca aacagtgacc atcgctagcc accgtaaaca
    24661 gaagaacttt gacattatta aattcaaaga tatgtaccat atcaatacta tcgaaaagta
    24721 caagggatac agtctcaagg tcgctgagga agatttgaat gacctagacg atggtgaatt
    24781 ttactatcac gagattatcg gtttggaagt ctatgagggt gatagcttgg ttggaaccat
    24841 caaggaaatc ctgcaaccag gtgctaatga tgtctgggtg gtcaaacgaa aaggcaaacg
    24901 tgatttgctt ttaccttata tcccaccagt ggttctcaat gttgatattc caaataaacg
    24961 ggtcgatgtg gaaatcttag aagggttaga cgatgaagat tgatatttta accctctttc
    25021 cagagatgtt ttctccactg gagcactcaa tcgttggaaa ggctcgagaa aaagggctct
    25081 tggatatcca gtatcataat tttcgagaaa atgctgaaaa ggcccgtcat gtagatgatg
    25141 agccctacgg aggcggtcag ggcatgttgc tcagagcaca acctattttc gattcctttg
    25201 atgctattga aaagaaaaat ccgcgcgtta ttctccttga tcctgctgga aagcagtttg
    25261 atcaggctta tgctgaagat ttggctcaag aggaagagct aatctttatc tgtgggcact
    25321 atgagggtta tgatgagcgc attaagacct tggtaacaga tgagatttcc ctaggtgact
    25381 atgtcctcac tggtggagaa ttggcagcta tgaccatgat tgatgctaca gttcgcctga
    25441 ttccagaagt gattggcaag gagtctagcc accaagatga tagtttttct tcaggtcttt
    25501 tagaatatcc tcagtacaca cgtccctatg attatcgagg catggtcgtg ccagatgtat
    25561 tgatgagtgg ccatcatgaa aagattcgtc agtggcgatt gtacgagagt ttaaagaaaa
    25621 cctacgagcg cagaccggat ttacttgaac attatcaact gacagtagaa gaagaaaaaa
    25681 tgctggcaga aatcaaagaa aacaaagaat aaaggagaaa cctatgcaag taatcaaacg
    25741 taatggcgaa attgctgaat ttaatccaga taagatttac caagccatct tgaaggcagc
    25801 ccaaactgtt tatgttttga cagatgattt gcgtcaaaat cttgctcaag tcactaagaa
    25861 ggtagttttg gatttacaag aagccaaggt ggaacgtgcg actatcagta tgattcaatc
    25921 tatggttgaa catcgtttat tgggcgcagg ttacattacc attgcagaac actatatttc
    25981 ctatcgttta caacgtgact tggaaagaag tggttatgga gatcatatcg cagttcattt
    26041 acattttgaa caaattcgct aagaaaaaga gtgggatgaa gcaactacat ctcactcttt
    26101 cttaaatcta tttttttggg ctgtttggac agttgagggg acaaatcgca ggcgttgaat
    26161 atcgcttata cggataatcc ggctcacatt tttggaaaaa tttttcacga taatttgctg
    26221 gccttgctga tcatatttga tgatgtcacc tgtaaagctt gtctcagata agataaggtg
    26281 aacagcggtt tgtttctgga tagcctcttc aatagtggct gtaagggagt tggtttcagt
    26341 ctggtcaggt tggtcatatc catttaaaaa atcatgtatt ttatttagaa cttgctggaa
    26401 tttatgtctc atattggcct cccttctttt atatcaatat tatataaaat tttcctaaaa
    26461 tctacaagat tttacgaata aactaatgaa actaaaaaag gagaagaaaa tggcagaatt
    26521 tacatttgaa atcgaagagc acttgttgac tctttctgaa aacgaaaaag gttggaccaa
    26581 ggaaattaac cgtgtgagct ttaatggtgc ccctgcaaag tttgatattc gtgcttggag
    26641 tccagaccat actaaaatgg gcaaagggat tactctctca aatgaagaat ttcaaacgat
    26701 ggtggatgcc tttaaaggca actaatactc ttcgaaaatc tcttcaaacc gcgtcagctt
    26761 tgccttgccg tatgtatggt tactgacttc gtcagtttca tccacaacct caaaacagtg
    26821 ttttgagcag cctgcggcta gcttcctagt ttgctctttg attttcattg agtataagtt
    26881 ttcaaaataa aagaaaagga tattgagtca tgataactcg atatcctttt ttagttagta
    26941 aagtaagcct gatttttaag gcgttgaagt aggggacggc taataaaact aatagccaga
    27001 agtttgccaa ggtctggaat gataaaggga agaaccccca cagcaagagc tttttcaaat
    27061 gccattccag ctaggaaatg caagctgaga atcccgccga caaagacaag ggcatcaccc
    27121 aagaggtttg caagaaaaat cttaacaaca ccactcttgc tgttggttag agaggaagta
    27181 agtccagagt aaacgagata aaaccaaaga tagcctgcag tagggccaac taaagcctga
    27241 aaaccagctc cacctcctgc aaagacagga agaccgatag cacctagaag aagatagagt
    27301 ccagcagaaa gtacagcctc tctcggtcta aagacagtag caatcaagcc gattgcaaag
    27361 ttttgcagag tgaagggaac aggtccaatt ggaagactga tttgtgccaa agcagcaatg
    27421 agagcagccc caatagcagg gatagcataa acgtgagctt ttttcaaaat agttaacctc
    27481 ttttctaatg tatagtaact attatactca tataggagtc gatgtcaacc attttttaaa
    27541 aacaaggtaa caaaaactgt aacagccgat tttcgtgact agtcaagttg gataattttt
    27601 ttgttgattc gaaaatcatt aaaaaagaag cagacatatt tatatcagct tcttttgttt
    27661 cgattaacgc atggttacaa attcttcaga tgaagttggg tgaatcgcta cagttgcgtc
    27721 aaagtcagcc ttggttgctc ccattttgat agcaacagca aatccttgaa tcatttcatc
    27781 aacgccgtag ccaattccgt gaagtccgac aactttttct tctgaaccag ctgttatgag
    27841 tttgaaacgg gattcttgac ggttgcgagt gcaagcagag tacatagatg caaagcttga
    27901 tttgtaaacc ttgatttggt cttgaccgta ttctttaata gcttgctctt ctgtcaaacc
    27961 aacagttccg atagcagggt gtgaaaagac aacagttgga atagttgagt aatccatttt
    28021 tgcagtagtt tttccgttaa agagacgttc agatagggta cgtccggcct tgattgcaac
    28081 tggagtcagt tctttctcgc ccgttacatc acctagagca tagattccct caacaacagt
    28141 attttggtat tcatccactt ggataaagcc acgttcgttc agagtcactc cagctttttc
    28201 aagttgcaag cccttaacgt ttggacggcg gcctgtagcc cagataactt ggctagctgt
    28261 gtgactagta ccatcttcga aatgaatggt aatgccgtca gtagtttttt ctaacttgac
    28321 agggactttg tgagtgtgaa gtggtaagtt tgttctttcc atttccttga ccaaaccttc
    28381 aacgatgtag gaatcaaaac cacgtaaagg acgatcgcgg cgaacaaaga gatctgtctt
    28441 gacaccaaaa gtgtggagta cgccagctaa ttcaacggcg atataaccag cgcctagaat
    28501 ggcaactgac tctggaagtt cttcccaggc aaatacatca tcagaagagc cacctagctc
    28561 agcaccagga atattaggaa tacttggatg ggcacctgta gcaatcacga tatgtttagc
    28621 acgaatcagt tcaccattta cgcttacagt atgagaatct acaaattcag catgaccttc
    28681 aatcaagtct acaccgttgc gtttaaaact gccatcataa gaagaacgag cgcgatcaat
    28741 gtaggattca cgattgcgac gtagggttgc aaagtcaaag ttaagatcag tagtcttaaa
    28801 gccgtagtct tctccaaatt gatggaaagt ctcagcgatt tgtgccccgt accacatgat
    28861 ttttttagga acacaaccga cgttgacaca ggttccacct aatttctttt cctcaataac
    28921 ggctgcttgg gctccatgtt caccagcacg gttcatggta gcgattcctc cgctacctcc
    28981 accgatagca atgatatcat attctctcat tgaaaactcc tttgtaatct tttaaatagt
    29041 agagcgtctt ttttgatagt tatattttat tctttttttg atttgattgc aaaaatctgc
    29101 tacgcacaaa aaattgcaaa aaagcttgcc aaataagtca agatagtgta ttatatatct
    29161 agtacaatag aaaagcaaaa ttccgaacga ttgtttaatc ctgaactgta ttgtttgctg
    29221 gagggaaatt tggtataata gcaaagtatt gtaaaaaaga aaaggagttt cattatgaag
    29281 aaaaagaatg gtaaagctaa aaagtggcaa ctgtatgcag caatcggtgc tgcgagtgta
    29341 gttgtattgg gtgctggggg gattttactc tttagacaac cttctcagac tgctctaaaa
    29401 gatgagccta ctcatcttgt tgttgccaag gaaggaagcg tggcctcctc tgttttattg
    29461 tcagggacag taacagcaaa aaatgaacaa tatgtttatt ttgatgctag taagggtgat
    29521 ttagatgaaa tccttgtttc tgtgggcgat aaggtcagcg aagggcaggc tttagtcaag
    29581 tacagtagtt cagaagcgca ggcggcctat gattcagcta gtcgagcagt agctagggca
    29641 gatcgtcata tcaatgaact caatcaagca cgaaatgaag ccgcttcagc tccggctcca
    29701 cagttaccag cgccagtagg aggagaagat gcaacggtgc aaagcccaac tccagtggct
    29761 ggaaattctg ttgcttctat tgacgctcaa ttgggtgatg cccgtgatgc gcgtgcagat
    29821 gctgcggcgc aattaagcaa ggctcaaagt caattggatg caacaactgt tctcagtacc
    29881 ctagagggaa ctgtggtcga agtcaatagc aatgtttcta aatctccaac aggggcgagt
    29941 caagttatgg ttcatattgt cagcaatgaa aatttacaag tcaagggaga attgtctgag
    30001 tacaatctag ccaacctttc tgtaggtcaa gaagtaagct ttacttctaa agtgtatcct
    30061 gataaaaaat ggactgggaa attaagctat atttctgact atcctaaaaa caatggtgaa
    30121 gcagctagtc cagcagccgg gaataataca ggttctaaat acccttatac tattgatgtg
    30181 acaggcgagg ttggtgattt gaaacaaggt ttttctgtca acattgaggt taaaagcaaa
    30241 actaaggcta ttcttgttcc tgttagcagt ctagtaatgg atgatagtaa aaattatgtc
    30301 tggattgtgg atgaacaaca aaaggctaaa aaagttgagg tttcattggg aaatgctgac
    30361 gcagaaaatc aagaaatcac ttctggtttg acaaatggtg ctaaggtcat cagtaatcca
    30421 acatcttcct tggaagaagg aaaagaggtg aaggctgatg aagcaactaa ttagtctaaa
    30481 aaatatcttc agaagctacc gtaatggtga ccaagaactg caggttctca aaaatatcaa
    30541 tctagaagtg aatgagggtg aatttgtagc catcatggga ccatctgggt ctggtaagtc
    30601 cactctgatg aatacgattg gcatgttgga tacaccaacc agtggagaat attatcttga
    30661 aggtcaagaa gtggctgggc ttggtgaaaa acaactggct aaggtccgta accaacaaat
    30721 cggttttgtc tttcagcagt tctttcttct atcgaagctc aatgctctgc aaaatgtaga
    30781 attgcccttg atttacgcag gagtttcgtc ttcaaaacgt cgcaagttgg ctgaggaata
    30841 tttagacaag gttgaattga cagaacgtag tcaccattta ccttcagaat tatctggtgg
    30901 tcaaaagcaa cgtgtagcca ttgcgcgtgc cttggtaaac aatccttcta ttatcctagc
    30961 ggatgaaccg acaggagcct tggataccaa aacaggtaac caaattatgc aattattggt
    31021 tgatttgaat aaagaaggaa aaaccattat catggtaacg catgagcctg agattgctgc
    31081 ctatgccaaa cgtcagattg tcattcggga tggggtcatt tcgtctgaca gtgctcagtt
    31141 aggaaaggag gaaaactaag atgcagaatc tgaaatttgc cttttcatct atcatggctc
    31201 acaagatgcg ttctttgctt actatgattg ggattattat cggtgtttca tcagttgttg
    31261 tgattatggc tttgggtgat tccctatctc gtcaagtcaa taaagatatg actaaatctc
    31321 agaaaaatat tagcgtcttt ttctctccta aaaaaagtaa agatgggtct tttactcaga
    31381 aacaatcagc ttttacggtt tctggaaagg aagaggaagt tcctgttgaa ccgccaaaac
    31441 cgcaagaatc ctgggtccaa gaggcagcta aactgaaggg agtggatagt tactatgtaa
    31501 ccaattcaac gaatgccatc ttgacctatc aagataaaaa ggttgagaat gctaatttga
    31561 caggtggaaa cagaacttac atggacgctg ttaagaatga aattattgca ggtcgtagtc
    31621 tgagagagca agatttcaaa gagtttgcaa gtgtcatttt gctagatgag gaattgtcca
    31681 ttagtttatt tgaatctcct caagaggcta ttaacaaggt tgtagaagtc aatggattta
    31741 gttaccgggt cattggggtt tatactagtc cggaggctaa aaggtcaaaa atatatgagt
    31801 ttggtggctt gcctattact accaatatct ctcttgctgc gaattttaat atagatgaaa
    31861 tagctagtat tgtctttcga gtgaatgata ccagtttaac cccaactctg ggtccagaac
    31921 tggcacgaaa aatgacagag cttgcaggct tacaacaggg agaataccag gtggcagatg
    31981 agtccgttgt atttgcagaa attcaacaat cgtttagttt tatgacgacg attattagtt
    32041 ccatcgcagg gatttctctc tttgttggag gaactggtgt catgaacatc atgctggttt
    32101 cggtgacaga gcgcactcgt gagattggtc ttcgtaaggc tttgggcgca acacgtgcca
    32161 atattttaat tcagtttttg attgaatcca tgattttgac cttgttaggt ggcttaattg
    32221 gcttgacaat tgcaagtggt ttaactgcct tagcaggttt gttactgcaa ggtttaatag
    32281 aaggtataga agttggagta tcaatcccag ttgccctatt tagtcttgca gtttcggcta
    32341 gtgttggtat gatttttgga gtcttgccag ccaacaaggc atcgaaactt gatccaattg
    32401 aagcccttcg ttatgaatga gatcaacaag atggacactc gtctatcttg tttttgtatg
    32461 gatttcccta tcgaaattca ttaaaaatgt gatataatga agtgttagaa aaacaggttt
    32521 catttgcctg gaaaggaaaa attatgtctg aaaaaaattt ttatattaca acgccgattt
    32581 actatccatc tgggaaactt catatcggtt ctgcctacac aactatcgca tgtgatgtcc
    32641 tagcacgtta caaacgcctg atgggctacg atgtatttta tctgacaggt cttgatgaac
    32701 atggtcagaa aatccagcag aaagcggaag aagctggtat tacacctcaa gcctatgttg
    32761 atggaatggc ggttggagtt aaagaactct ggcaattact agatatctca tacgataaat
    32821 ttatccgtac aactgatgac taccatgaaa aagttgtcgc acaagtcttt gaacgcttac
    32881 ttgctcaaga tgatatctac ttgggtgaat actctggttg gtattcagta tcagacgaag
    32941 aattctttac agaaagccag ctggcagaag ttttccgtga tgaagctgga aatgtgactg
    33001 gtggtattgc tccatcaggt catgaggttg aatgggtttc tgaagaatca tacttccttc
    33061 gccttagcaa ataccaagac cgtttggtcg aatttttcaa agctcatcct gaatttatca
    33121 cgccagatgg tcgccttaat gaaatgctac gcaacttcat cgagccaggc ttggaagatt
    33181 tggcggtatc tcgtacaacc tttacatggg gagtgcctgt cccatcaaat ccaaaacacg
    33241 ttgtctacgt ttggattgat gcccttctta actatgcgac agctcttggc tacgctcaag
    33301 acgaacatgg taactttgac aagttctgga atggaacagt cttccatatg gtaggaaaag
    33361 atatccttcg cttccactct atctactggc caatccttct tatgatgttg gatgttaaat
    33421 tacctgatcg tttgattgcc catggttggt ttgtcatgaa agacggaaaa atgtctaagt
    33481 caaaagggaa tgtcgtttac cctgaaatgt tggtagagcg ttatggacta gatccacttc
    33541 gttactacct catgcgtaac cttccagttg gttcagacgg aacctttact cctgaagact
    33601 atgtcggccg tatcaactat gaattggcta atgaccttgg gaacctcctt aaccgtacgg
    33661 tttccatgat taataagtac tttgatggac aaatccctgc ctatgtagaa ggtgtgactg
    33721 aatttgatca tgttcttgct gaggttgcag aacaatcaat cgcagacttc catacacaca
    33781 tggaagcagt tgactatcca cgtgcgcttg aagcagtctg gactctgatc tctcgtacca
    33841 ataaatacat cgatgagacc gcaccatggg tcttggccaa ggatgaagct cttcgtgacc
    33901 aattggcaag tgtcatgagc cacttggcag ccagcattcg tgtagttgct cacttgattg
    33961 aaccatttat gatggaaact agtcgtgcag ttttgactca acttggtttg gaagaagttt
    34021 ctagtcttga aaacttgagt ttggctgact tcccagcaga tgtgactgta gttgccaaag
    34081 gaacacctat ctttccacgt ctaaatatgg aagaagaaat cgcctatatc aaggaacaaa
    34141 tggaaggcaa taaaccagca gtcgaaaaag aatggaatcc ggacgaagtt gagctcaaac
    34201 taaacaagga tgaaatcaag tttgaagact ttgacaaggt tgaaatccgt gtcgcagaag
    34261 tcaaagaagt gtctaaagta gaaggttcag ataagttgct tcaattccgc ttggatgctg
    34321 gtgatggaga agatcgtcag attctttcag gaattgcaaa atactatcca aatgaacaag
    34381 aattggtcgg caagaaagtt caaatcgttg ctaacctcaa accacgtaaa atgatgaaaa
    34441 aatatgtcag ccagggtatg attctctcag ctgaacatga tggcaaatta acccttctca
    34501 cagttgatcc agctgtacca aatggaagtg tgattgggta aaagtagaca ggactagttc
    34561 aggctagttc tgttttttta tttatactca atgaaaatca aagagcaaac taggaagcta
    34621 gccgcaggt
//
LOCUS       DBERPV010000017        34239 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.17, whole genome shotgun sequence.
ACCESSION   DBERPV010000017 DBERPV010000000
VERSION     DBERPV010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 34239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34239
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.17"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(193..1179)
                     /locus_tag="ACL8C7_001136"
     CDS             complement(193..1179)
                     /locus_tag="ACL8C7_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS1395349.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(1189..1989)
                     /locus_tag="ACL8C7_001137"
     CDS             complement(1189..1989)
                     /locus_tag="ACL8C7_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HGS1395350.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(2242..3084)
                     /locus_tag="ACL8C7_001138"
     CDS             complement(2242..3084)
                     /locus_tag="ACL8C7_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HGS1395351.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHSWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(3086..4378)
                     /locus_tag="ACL8C7_001139"
     CDS             complement(3086..4378)
                     /locus_tag="ACL8C7_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HGS1395352.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(4489..5760)
                     /locus_tag="ACL8C7_001140"
     CDS             complement(4489..5760)
                     /locus_tag="ACL8C7_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGS1395353.1"
                     /translation="MSSKFMKSTAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            6295..7827
                     /gene="malQ"
                     /locus_tag="ACL8C7_001141"
                     /pseudo
     CDS             6295..7827
                     /gene="malQ"
                     /locus_tag="ACL8C7_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004134 - 4-alpha-glucanotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005980 - glycogen catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
     gene            7853..10111
                     /gene="glgP"
                     /locus_tag="ACL8C7_001142"
     CDS             7853..10111
                     /gene="glgP"
                     /locus_tag="ACL8C7_001142"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HGS1395354.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDSAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(11156..11728)
                     /locus_tag="ACL8C7_001143"
     CDS             complement(11156..11728)
                     /locus_tag="ACL8C7_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395355.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHVAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(12506..13354)
                     /locus_tag="ACL8C7_001144"
     CDS             complement(12506..13354)
                     /locus_tag="ACL8C7_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative RNA methyltransferase"
                     /protein_id="HGS1395356.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSKLTEITIEAEI
                     LVGKAF"
     gene            13506..13784
                     /locus_tag="ACL8C7_001145"
     CDS             13506..13784
                     /locus_tag="ACL8C7_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6110 family protein"
                     /protein_id="HGS1395357.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            13786..15849
                     /locus_tag="ACL8C7_001146"
     CDS             13786..15849
                     /locus_tag="ACL8C7_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGS1395358.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRICVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(15927..17183)
                     /gene="tyrS"
                     /locus_tag="ACL8C7_001147"
     CDS             complement(15927..17183)
                     /gene="tyrS"
                     /locus_tag="ACL8C7_001147"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HGS1395359.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            17325..19790
                     /gene="pbp1b"
                     /locus_tag="ACL8C7_001148"
     CDS             17325..19790
                     /gene="pbp1b"
                     /locus_tag="ACL8C7_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1B"
                     /protein_id="HGS1395360.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            19855..20766
                     /locus_tag="ACL8C7_001149"
     CDS             19855..20766
                     /locus_tag="ACL8C7_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGS1395361.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            20996..21694
                     /gene="dapD"
                     /locus_tag="ACL8C7_001150"
     CDS             20996..21694
                     /gene="dapD"
                     /locus_tag="ACL8C7_001150"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HGS1395362.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            21762..22892
                     /locus_tag="ACL8C7_001151"
     CDS             21762..22892
                     /locus_tag="ACL8C7_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HGS1395363.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            22904..23443
                     /locus_tag="ACL8C7_001152"
     CDS             22904..23443
                     /locus_tag="ACL8C7_001152"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HGS1395364.1"
                     /translation="MKSELRKQVLHEMKALSQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDPQQLVKTAFALLEPQ
                     GDLEVVDVSQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            23427..24104
                     /locus_tag="ACL8C7_001153"
     CDS             23427..24104
                     /locus_tag="ACL8C7_001153"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HGS1395365.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(24171..25070)
                     /gene="galU"
                     /locus_tag="ACL8C7_001154"
     CDS             complement(24171..25070)
                     /gene="galU"
                     /locus_tag="ACL8C7_001154"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HGS1395366.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYKRTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFAREFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(25092..26108)
                     /locus_tag="ACL8C7_001155"
     CDS             complement(25092..26108)
                     /locus_tag="ACL8C7_001155"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HGS1395367.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEIRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            26625..26759
                     /locus_tag="ACL8C7_001156"
     CDS             26625..26759
                     /locus_tag="ACL8C7_001156"
                     /inference="COORDINATES: protein motif:HMM:NF037495.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395368.1"
                     /translation="MFEEYYDRLPEEERFIIPNYSYLALTNYTVQKLPEKLVEILSFW
                     "
     gene            complement(26874..27308)
                     /locus_tag="ACL8C7_001157"
                     /pseudo
     CDS             complement(26874..27308)
                     /locus_tag="ACL8C7_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(27376..28026)
                     /gene="phoU"
                     /locus_tag="ACL8C7_001158"
     CDS             complement(27376..28026)
                     /gene="phoU"
                     /locus_tag="ACL8C7_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HGS1395369.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLNMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(28041..28793)
                     /gene="pstB"
                     /locus_tag="ACL8C7_001159"
     CDS             complement(28041..28793)
                     /gene="pstB"
                     /locus_tag="ACL8C7_001159"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGS1395370.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDVLLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(28795..29610)
                     /gene="pstA"
                     /locus_tag="ACL8C7_001160"
     CDS             complement(28795..29610)
                     /gene="pstA"
                     /locus_tag="ACL8C7_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HGS1395371.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(29603..30466)
                     /gene="pstC"
                     /locus_tag="ACL8C7_001161"
     CDS             complement(29603..30466)
                     /gene="pstC"
                     /locus_tag="ACL8C7_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HGS1395372.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(30584..31459)
                     /locus_tag="ACL8C7_001162"
     CDS             complement(30584..31459)
                     /locus_tag="ACL8C7_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HGS1395373.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(31626..32957)
                     /gene="pnpS"
                     /locus_tag="ACL8C7_001163"
     CDS             complement(31626..32957)
                     /gene="pnpS"
                     /locus_tag="ACL8C7_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system histidine kinase PnpS"
                     /protein_id="HGS1395374.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGLGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKGNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(32958..33665)
                     /locus_tag="ACL8C7_001164"
     CDS             complement(32958..33665)
                     /locus_tag="ACL8C7_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS1395375.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(33749..34234)
                     /locus_tag="ACL8C7_001165"
     CDS             complement(33749..34234)
                     /locus_tag="ACL8C7_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HGS1395376.1"
                     /translation="MAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
BASE COUNT        10103 a         6462 c         7327 g        10347 t
ORIGIN      
        1 gtgttttgag caacctgcgg ctagcttcct agtttgcact ttgattttca ttgagtataa
       61 aaagatcttg ggaaaagact caatttcagt agaaaaggaa gtaaatcttc ccacaataaa
      121 acgcatagta tcaagttttt tcaatacctg atactatgcg tttttgcttt taacgacttt
      181 ttacccagtc tcttattttt cgataatttt gtgggcgatc aattgacggt aacaaatttg
      241 tttattgttt ttattatcat taataatctg gagaatagtt tcaagggaaa cacgaccaag
      301 ctctaaacta ttgatatcga cataggctgc caagttgagc ttgggattaa ccgagtcaaa
      361 gctgagaaca gggacatcca gctggtgttt ggcaatatag ttacaaacac cttcagctag
      421 gaggctatcg gttgtgatga tagcatcaat ttgtggatcg tgcttgaata atcgcttgct
      481 aaatttatag cccttttctt ccagaaactc gtcggcaaag tagatgcgat tgttgtcagt
      541 ggtaagtttg taatgtttaa gcgcctgttc atagcctgtt aaacggtctt tggtcacgaa
      601 gagcttttta cttcctccga taaaggcaat gcgtttgcag ccttttttga tgaaatattc
      661 agtcgcatca aaaccagctt gaacattgtc gttgtcgaca agtgggatga aaggagatag
      721 agatttacct aagataagga aggggaactg ttcttctgcg acgagtttta cgagagggtc
      781 ttcttcttgg gcatagagaa agattagccc atctacacgc ttgccgtaga ccatttgtga
      841 aatagcgttg agacgctcct tctcatcttt ccctgttgct atctgaatgg catagtggtt
      901 ttcagatgcg acttgagaga tgccacgtag aaccgatgga aagaaaggat tctggtagaa
      961 ggcgtctgag tcatcaggaa gaactaatcc gataacctga gtatagctgc ttaccaagct
     1021 acgagcgttg aggtttgggt ggtagttgag ttccttcata gctttgcgaa cgcgtttttt
     1081 tgtttcgtcg ctaatggttg atttattttg aataacacgg gttacggttg aaggcgaaac
     1141 accagcagcc ttggccacgt ctttaatcgt aacgggcata aaaatctcct atttatggta
     1201 atttggatca cggaaatgtg ttttataaaa gatagtgacc agatacagaa caaaaagaat
     1261 attttgtaca gtaatcaggg ttgtcatatt ttggccaaat aatcccaaaa taagtgtaat
     1321 cagagtcggc aatcctaaac agttcaagat aaagtgatag cactctttaa aggttctaaa
     1381 tgaaaagagg cgtgatttct tagtgatata aaggagaaga ctagctccta gagagacgat
     1441 aaagaaattc aaaccaaaga ggaagctcgc accgagaact aggaagaggc tgatatagac
     1501 acgattttgt tggtaccagt ctttagaaat tgcttgggtc aagctgtctt tgcttttgaa
     1561 actctcagtc tgaatggctc ggtaagagat gcgggtcagt tccttgcttt ccttgctgat
     1621 gactagctca tttgtatcga aatgcagttg caagtcctta ggtaattcct tgatttgact
     1681 tggaccaatc acaacagaag gagcttgact agctgttcca gtataagtta atgtgccatc
     1741 gacaattgta gcatgttcag agagatcctg gacaacctca tttgtcagag gttcatagac
     1801 attatcgata aaagtttcta gcggataggt ctcctgggag ctgttttgga tagcaatggg
     1861 taccatagat aagctgataa ggaagatact ggtaaagaga agttgaaacc agttgagctc
     1921 gaaacgtttg gacaggggct tacgaaaccc ccaaatactt gaaaaatagg aaaatggata
     1981 tggaagcata ggtatctttc taaaaggtgt tttctatatg agtattatta tatagagaaa
     2041 tgcgctttat ttcaagtcta ggagaaaaat tgcttgctac aaggatatta tttacagtga
     2101 caattgctaa taatcaatga aaatcaaagt gcaaactagc cacaggttgc tcaaagcaca
     2161 actttgaggt tggagataaa gctgacgtgg tttgaagaga ttttcgaaga gtataaaatg
     2221 aaaaagggtg gcggggataa attatccctt gtcgccacca cttgtaagtc ctgaaacaaa
     2281 gttcttttgt aggaagaaga agagaataca gattggaagg gcgatgagga tagcacctgc
     2341 tgagaagtag gcaatcttca agtttttcgc attgttaacg aaggtttgga gacctacggc
     2401 aacagtaaag tattctttct cacgaagcaa gaaactagag aggatgtagt ccccgaaagg
     2461 tcccatgaag gcccagagag cttgtacggc aaccattggg cgaacaagtg gaagaacaat
     2521 ttgccagaag cggcggaagt gtcctgcacc gtctagtttt gcagattcgt ctaaagacat
     2581 tggcactgta tcgaagtagc ctttcatgag ccaagcattc atcgggatac caccaccaac
     2641 gtagaggaag atgaggaacc agctgtggtt aagggcgttc aacataagcg ccataacgaa
     2701 gaaggctgtc aaagcggcca tagttggcac catttggatg atcaagaaga agaccaaact
     2761 ttgtttacga gccaagaagt tgtaacggct gtaagcataa ccagcaagta cgatgatact
     2821 tgtttgaaca gccatggtaa ttaaggcgat aatcaaagtg ttgaggtacc aagtaccgta
     2881 caaggtttca gtgaagaggc ctttaaagtt atcaaaattg aggtcgatat tagtatctag
     2941 tttaaaggct gagacgttac ctgctttaaa ggctgacata atggtaatca acagtggata
     3001 gataattaca attgatagac caatcaggta aaggtaagta aggctttgag tcagtctacg
     3061 tttgagttta attgagttat tcatcttaga cgtcctccat atcaaatgcg tgtagtttct
     3121 tgaatgcgat catagagatt gagatgacaa tgatagagat aatcaaggta acagctgccg
     3181 ccattgagta ttgaggagat gtacctgttg tcaaacggta gatccatgag atcaagatat
     3241 cggttgaacc agctccacct ccgacactac caggtcctcc accattgaag aggtacatga
     3301 tagagaagtt gttaaagttg aaggtgtatt ggctaatcaa agtaggtgcc gcaacagcca
     3361 aaatcattgg gaaagtgatg ttgcggaatt tttgccaagc gttggcaccg tcaatataag
     3421 ctgcttcgta aaggtcgtta ggaatagatt gcaagatacc caaagtcaaa acgtagatgt
     3481 atgggaatcc gagccaacct tgcatcataa tcaaggcaat cttagtccaa gttgggtctg
     3541 ttttccaagg aataagagct ccatcaagga aaggaaggaa tttagccaag attggcaata
     3601 cttgagtgtt gatagcaccg acactatcgt taaacatgtt tgagaatgtc aagatagtga
     3661 tgaaggctgg gacagcccaa ggaagaagga aaataacacc aaagatacgt tttcctttga
     3721 taaatggttg gttggcaatg atagctgtga agataccaat tacgatttgt aaagtagaag
     3781 ctgccaaagc ccaaatgata gtccaagaaa gaacagaacc aaaggcagaa cggaaggtac
     3841 tcaagctcca aatgtttgta aagttggtca aaccaaccca gtccaacaac ttgtttggtg
     3901 gcaagtgttg gaagtcgtag ttggtaaagg cgatcatcaa ggttacgata actgggaaga
     3961 taatcgcgaa ggtcatggca acataagatg gaatgatcaa gaggtaaggg aagccatttt
     4021 cataaatccc tttgatcatg tctttgagtg tgcgtggaac tggaattcca ttgttaatgc
     4081 gttttgcaat cgtatgtgca tctttgatat ttgagaaata aaagagtaca taaacgatta
     4141 caaagattag atggaaggca ccacgaatca gcataaagag ggaattatca cgacctggtt
     4201 tgtcaccaag agtgatgagg ttgctcaatt caggggttgc aagtgctagg aagtaaagga
     4261 caaatacgat ggttacacca aggaagataa aacctttggc tttttgttta ttgtaaatct
     4321 gtcctaaccc aggaatgata gacagcaggg ctgctttact aggttgttgc ttttccatat
     4381 taactccttt cataggatac tactttttta taagaaagct aaattatttg tgtctctatt
     4441 gataaattca aagggggatt tgatttccac cccccttgaa caaatttttt attcaccaaa
     4501 tttttgtttg attgtttctt tgatcaatgt tacagcatcg ttagcagctg ttttagcatc
     4561 tttttgacca cttacagcat caaagagcat atttttcgct ggatcccaaa ctgcagacat
     4621 ttgagagatg tttggcagtg gttgagtgtt cttgaactgt ttgataacag ctgttgtcaa
     4681 ctcatcgttt ttaccttcag cgtatgaacg agcctcagta ttagctggga tttcgttagt
     4741 cttatcatat aatacttttt gttgttcagt tgcaacaagg aagtctacaa atttttgaga
     4801 agcttcaagg ttcttaacgg cttgaggaat gacccaagct ttaccaccac cgaatgcagc
     4861 atattctttt ccatttggaa gagttgggat agttgcaact ccgtagttta ctttagcatc
     4921 tttaaaggct tgagctttcc aaggtccgtc gatgatagca gctgttttac cttcttggaa
     4981 ttgagtttgg attaagtttc cagcaccttc tgtatcttgc atacctttag gccatttttc
     5041 gtaccaagat ttagcgtagt tgatacctgc gatagaaccg tcgtttgcaa gaccgatgtc
     5101 tttagcgtct ttaccgtttt ggccaaagac gtaagcaccg ttaccggcaa gaagtccata
     5161 tgtatagtag aagtttgtcc agtcagctag gaaggcagta gttttaccat cttcaccagc
     5221 gaatgcgtat ttgctatctt tagcaaggtt ttccaagtca gcaaatgttt ttggagcatc
     5281 tttcaccaag tctttgttgt agtacataac aagtgactcg ataacggcag gagcaccgta
     5341 aactttacca ttagcagctg ttacaagaga tttagttgtg tcgtctgttt tagcaccatc
     5401 gctcaatttc acttctgaaa gttgtccgtc agaaccaagg ctacctacac ggtcgtatgg
     5461 agccatcata acatcaggga cattaccaga ttggttgtca agagaaagtt tatcaagacc
     5521 tcctagagca tcaccagttt taagagtgac ttttactcca gcttcttttt cataagcttt
     5581 agcaacctct tcaatatagc tcttatatcc ctcgtctaca tatacagtga gttctttgac
     5641 ttcagatgaa ccagaatcag caggcttatc agcagttttg cttccgcaag ctaccaaaag
     5701 caagctagca agtgtagcag ttccaagcac cgcagtgctc ttcataaatt tagatgacat
     5761 agtgtattcc tcccaaagaa tagcaagttt tattgataag gaaacgcaaa cgttttcctt
     5821 tatgagctta gtatagcaca aatagaaaac ggttgcaagt attttttgta aaaattttaa
     5881 aaaattttta agcttgattt gatagcataa ttttacattt taatagaaga aaagtatgaa
     5941 atagataaga atacagtatt tttaataaaa atatatggaa tctgtctaaa gagggaaatc
     6001 aggaggggct acctccctgt ttctaatccc tatctatttt ctatagacgt ttgtgctttg
     6061 ttgcatataa attcaagctc cctaaggagg ttttgtactt tgtagactgt ctcgtgagag
     6121 tcaaacttta ggattagata gttttaagtt atctttgcta aaatgagtta gtctccttaa
     6181 aaataatcaa aaaagttttt taaaaacgct tgcaattatg cttgaaaagg agtatactta
     6241 taagtaacgc aaacgtttgc gtctgaaaaa tacgcaacgt tccattattt taacacacga
     6301 ggtgctatta tgaaaaaacg tcaaagtggt gtgttgatgc acatctcttc tcttccagga
     6361 gcttacggaa tcggatcatt tggtcaaagt gcttacgact tcgttgattt cttggtccgt
     6421 acaaaacaac gttactggca aatccttcca ttaggagcaa ctagttacgg ggattctcct
     6481 taccaatctt tctcagcctt cgcaggaaac actcatttta tcgatttaga tatcttggtg
     6541 gagcaaggtt tgttgggagc gagtgacctt gaaggagttg actttggtag cgatgcgtct
     6601 gaagttgact atgctaaaat ctactatgca cgtcgtcctc ttttagaaaa agcggtgaaa
     6661 cgtttctttg aagtcggaga tgttaaagat tttgagaaat ttgctcaaga caaccaatca
     6721 tggcttgagc tctttgctga gtatatggct atcaaagagc attttgacaa tcttgcttgg
     6781 actgaatggc cagatgcaga tgctcgtgct cgtaaagctt cagcacttga aagctatcgt
     6841 gagcaattgg cagacaagtt ggtttaccac cgtgtgactc aatacttctt cttccaacaa
     6901 tggttgaaat tgaaagctta cgctaacgac aaccacattg aaatcgttgg ggacatgcca
     6961 atctacgtag cggaagattc aagtgatatg tgggcaaatc cacatctctt caaaacagat
     7021 gtcaatggta aggctacttg tatcgcagga tgcccaccag atgagttttc tgtaactggt
     7081 cagctttggg gtaacccaat ctatgactgg gaagcaatgg acaaagacgg ctacaaatgg
     7141 tggattgaac gcttgcgtga aagcttcaaa atctacgata tcgttcgtat cgaccacttc
     7201 cgtggcttcg aatcttattg ggaaatccct gctggttccg atacagcagc acctggtgag
     7261 tgggtgaaag gtccaggcta caagcttttt gcagccgtta aggaagaact tggtgagcta
     7321 aacatcatcg cagaagacct tggcttcatg acagatgaag tgatcgaatt acgtgaacgt
     7381 actggcttcc caggaatgaa gattcttcaa tttgccttca acccagaaga cgaaagcatt
     7441 gatagcccac acttggcacc tgctaactca gttatgtaca caggaacaca cgataacaat
     7501 acggttcttg gttggtaccg taatgagatt gatgatgcga ctcgtgagta catggctcgt
     7561 tacacgaacc gtaaagaata cgaaacagtg gtacacgcta tgcttcgtac agtattttca
     7621 tcagttagct ttatggcaat tgcaactatg caagatttac tagaattgga tgaggcagct
     7681 cgtatgaact tcccatctac ccttggtgga aactggtctt ggcgtatgac tgaagatcaa
     7741 ttgacaccag ctgtcgagga aggtttgctt gacttgacaa caatttatcg ccgaattaat
     7801 gaaaatttgg tagatttaaa gaaataagac aataatcagg agacaactaa acatgttatc
     7861 actacaagaa tttgtacaaa atcgttacaa taaaaccatt gcagaatgta gcaatgaaga
     7921 gctttacctt gctcttctta actacagcaa gcttgcaagc agccaaaaac cagtcaacac
     7981 tggtaagaaa aaagtttact acatctcagc tgagttcttg attggtaaac tcttgtcaaa
     8041 caacttgatt aaccttggtc tttacgacga tgttaaaaaa gaacttgcag ctgcaggtaa
     8101 agacttgatc gaagttgaag aagttgaatt ggaaccatct cttggtaatg gtggtttggg
     8161 acgtttggct gcctgcttta tcgactcaat tgctactctt ggtttgaatg gtgacggtgt
     8221 tggtcttaac taccactttg gtcttttcca acaagttctt aaaaacaacc aacaagaaac
     8281 aattccaaat gcatggttga cagagcaaaa ctggttggtt cgctcaagcc gtagctacca
     8341 agtaccattt gcagacttta ctttgacatc aactctttac gatattgatg ttactggtta
     8401 tgaaacagcg actaaaaacc gcttgcgttt gtttgacttg gattcagttg attcttctat
     8461 tattaaagat ggtatcaact ttgacaagac agatatcgct cgcaacttga ctctcttcct
     8521 ttacccagat gatagtgacc gtcaaggtga attgctccgt atctttcaac aatacttcat
     8581 ggtttcaaac ggtgcgcaat tgatcatcga cgaagcaatc gaaaaaggaa gcaacttgca
     8641 tgaccttgct gactacgcag ttgtccaaat caacgatact cacccatcaa tggtgattcc
     8701 tgaattgatt cgtcttttga ctgcacgtgg tatcgagctt gacgaagcaa tctcaattgt
     8761 tcgtagcatg actgcctaca ctaaccacac aatccttgct gaggcgcttg aaaaatggcc
     8821 tcttgaattc ttgcaagaag tggttcctca cttggtacca atcatcgaag aattggaccg
     8881 tcgtgtgaag gcagagtaca aagattcagc tgttcaaatc atcgatgaga gcggacgtgt
     8941 tcacatggct cacatggata tccactacgg atacagtgtt aacggggttg cagcacttca
     9001 tactgaaatc ttgaaaaatt ctgagttgaa agccttctac gacctttacc cagaaaagtt
     9061 caacaacaaa acaaacggta tcactttccg tcgttggctt atgcatgcta acccaagatt
     9121 gtctcactac ttggatgaga ttcttggaga tggttggcac catgaagcag atgagcttga
     9181 aaaacttttg tcttatgaag acaaagcagc tgtcaaagaa aaattggaaa gcatcaaggc
     9241 tcacaacaaa cgtaaattgg ctcgtcactt gaaagaacac caaggtgtgg aaatcaatcc
     9301 aaattctatc tttgatatcc aaatcaaacg tcttcacgag tacaaacgcc aacaaatgaa
     9361 cgctttgtac gtgatccaca aataccttga catcaaagct ggtaacatcc ctgctcgtcc
     9421 aatcacaatc ttctttggtg gtaaagcagc tccagcctac acaatcgctc aagacattat
     9481 ccatttaatc ctttgcatgt cagaagttat tgctaacgat ccagcagtag ctccacactt
     9541 gcaagtagtt atggttgaaa actacaacgt tactgcagca agtttcctta tcccagcatg
     9601 tgatatctca gaacaaatct cacttgcttc taaagaagct tcaggtactg gtaacatgaa
     9661 attcatgttg aacggagctt tgacacttgg tactatggac ggtgctaacg tggaaatcgc
     9721 tgagttggtt ggagaagaaa acatctacat cttcggtgaa gattcagaaa ctgttatcga
     9781 cctttacgca aaagcagctt acaaatcaag cgaattctac gctcgtgaag ctatcaaacc
     9841 attggttgac ttcatcgtta gtgatgcagt tcttgcagct ggaaacaaag agcgcttgga
     9901 acgtctttac aatgaattga tcaacaaaga ctggttcatg actcttcttg atttggaaga
     9961 ctacatcaaa gtcaaagagc aaatgcttgc tgactacgag gaccgtgacg catggttgga
    10021 taaagtcatc gttaacattt ctaaagcagg attcttctca tctgaccgta caatcgctca
    10081 gtataatgaa gacatctggc acttgaacta atactcttcg aaaatctctt caaaccacgt
    10141 cagctttatc tgcaacctca aagcggtgct ttgagcaacc tgcggctagc ttcctagttt
    10201 actctttggt tttcattgag tataagatac aaatttatac taatacattt tgtaaaaaag
    10261 cgagtttcga ttgaaattcg cttttttaaa tgctgtggat ttgggtcaat cttgtctaaa
    10321 aatagggaaa tcctagatac agtgaaggct ttaaatgctg gtttttactg tcttcagcct
    10381 tatatttttt cgtagttggt tacctcataa ctcttgtatt cgcttacata aagtattata
    10441 atataattgt aggaaagaag gtgtttttat gatatacaca cttaaattgg tgttgtttat
    10501 tacctttctt gtaataagct tgttacctga taagattttt ggaaaaaata aaaaaatttg
    10561 gaaaatagtt tttgcaatat tgacggcagt ggcagcattg tcatttatgt actaagttat
    10621 tttaagaatg tagggaaata aaccctacat tctttttagt tttttctgtt ttctaaattc
    10681 tatttatcca agcgcttcaa catttcttgc ttcttcgctt caagttctgc acgcttttct
    10741 tcgatttcgg catgtttttt ctcgagttca gaacaacttg catcattgct aaattctttt
    10801 cgccatcagg agatagggtg agtcgacatg tctattactc acccaaagca gtcctacaaa
    10861 gcaggaattt tctgttactt ttttggaaat agtaacgttt atacagcttt gacacttcgt
    10921 atcaaagcgc caaacacact ccgagggatt tacagaaagc agaaaaggaa tgatctggta
    10981 taagatcatt ccttttctct ctttttcttt aagtaattat atacaatgta cgacgaagtc
    11041 gtcattgcaa tgctgatcca ccacctaaag ggaactttaa acaacattga taagataaag
    11101 aatataaaca acgaaaatac gttataccca attaatttta ttgtatatct catgattaaa
    11161 agttaatcct tccgttgtta ggaatggcat catttttatc ccataattgt gctaaataag
    11221 tccccggtga taataaattc atagcgaatt ctaaagcaac atcatttaca aaccaactac
    11281 ctagatatct agaaattgct gaacgaatag cactttttgc tacatgtttt ccttttactt
    11341 taattagatt tgcaaggcct gcagtagttc ctcctaatgc taaagctatt gcagtatcta
    11401 atagagcacc catttgatta actgtaatac cttgccaagc tgctctaaat ggagagtatg
    11461 taggtgggat tgtataatcg ccttgtaatt gtcggttaat tacttctttg atccattgtt
    11521 gtgagacgtc tggatgaaaa gattggattt cgtttgcaag tgtattgatt tgttcttctg
    11581 ttagagaagt gacaggttga agttccatat ttgtttcaat ttgtgatact tgttcagaag
    11641 cgtatacagc tgaaacactt ggaatcgctg atacaattaa cacaattgac gtcaaaaaaa
    11701 ccgaaataaa tttcattaat ttgttcatga gcttttctcc tttttatttg tatctgctta
    11761 cattttatca tatactgtta ttatagtcaa aaaaatattt ttcaaaatat aaatggacgg
    11821 atttattttg gattttattt gttattttga cctgcctcta tattggtaac catgatttgt
    11881 ttactctcaa tcatcaagaa ttctcttttc gtggtagcgt ttggggtctg gtactggcct
    11941 tatatcactt attgttcatt gataagtttg taatttcgaa tcgaaaataa agattagaac
    12001 tatgattgac tggctacttt taatattgat tttggaggaa gattttgtct ctattattta
    12061 ttattttaaa tttatttatt ttgtataaga tctattcttt gaggcgggaa aaatcgaaat
    12121 acttgattta tacggcctat atcatatttg gggtaaatgt agtatatggt attcaatggt
    12181 tattaagaga actgatttca aatatttccc cttaatgtgt atggaaacta taacaaaacg
    12241 cataagatta aggtttgtgt acctgttctt atacgttttt gtcatattga agattttcgg
    12301 taagttttct acttttgcga agtctagttt atactcaatg aaaatcaaag agtaaactag
    12361 ccgtaggttg ctcaaagtac agctttgagg ttgcagataa aactgacgaa gtcagctcaa
    12421 aacatggttt tgaggttgta gatgaaactg acgaagtcag taaccatacg tacggcaagg
    12481 cgacgttgac gtggtttgaa gagtattaga atgctttccc aaccaaaatc tctgcttcga
    12541 tggtaatctc tgtcagtttg ctccagtcaa ttttgctctg gtcaacgtga aagaggagag
    12601 gagtcatact gagtagggct tggagttgtt ctgctgtgat agtcttagtc agagaggcag
    12661 tttgactaga taggatggta aagtgttcct ggaaatgctc cttgatatct tggttagaat
    12721 actccttgtt tgtcagctgg tcctgtactc tttgacggat ttctttgagg tgattttcag
    12781 ttgggataac ctttatcaag ataccgtctt tggataaaac gcgacgaaat tctccatagt
    12841 tggcaggtga gaagatatca agcagaatat ccatgttagc gtcttttata ggaagtcgtg
    12901 ccaagtcgcc aacgaaccaa ttgactgccc agttgggttc acttttagca gcgatttgga
    12961 ctgaatcttt ggagatgtca aaggcataga aagttttttc agagtgactt tcttgtagtt
    13021 tgcgagaata gaatccttca ccacaaccga tatccaaaat tgttgtggta gtttttgagc
    13081 ttgcaagcaa gtcagataca gcatctaaga tagcttggta aaagccggct tctaggattt
    13141 gttgacggtt ttgaaaattt tccttgtcat agttagcaga ttgcttgatt tgaggtgcta
    13201 gattgacata gccaaatttc gccaagtcaa aagaatgacg gttgcagcac ttgaaattag
    13261 tctctaacag agtcagattt tcttgacaga taggacaggc aaaggcagtc gcagaagcaa
    13321 aacgctgaag tttgggcttg agatttgtat tcatagttta agtgtatcaa aagaggcaaa
    13381 tgaaagcaac tttaggaata agtagatggg agattcagta gaaataaaac taattctcca
    13441 atttatagaa tgaaattgct tttatatcta aattgctata taataatgat aaggaggaaa
    13501 taagtatgtt aaaagaagta ttaaccgttg caaaagttgc gaaaaaatct tcattatttt
    13561 tgggtggtgt cgcatttggt acccttggtt tgaaaatctt agcaagtaag gaagctaaaa
    13621 aaggttattc taaagctttg gctaaggctt acaagttgaa agacgagcta gatgcatctg
    13681 tttctgtcgt gaagcaacat ggagacgatg tcttgcaaga tgccaaatat ttgtacgagc
    13741 aagagaaaaa agaagagcaa ttagatagcc ttataggtga ataatatgtc ttttaaagtg
    13801 ctacatagag gataccaaca tatccgacta tcatcttctt tttcacttac cttggatatt
    13861 caagactatc ttcgttcctt ggcgagagat gaaaagggga ttgagtctat ccagttttac
    13921 atggatcaac agcactttac tctacgcata aaagaaggct tttctgtatt agataatgca
    13981 gaagcctttt taaaaagaat tgataaaggg aaagtttctg agttgatgac tcttcccatt
    14041 cgtagagaag agagtgctta ttctattgtt tcaggtgcag cggttaagcg tgtacttttt
    14101 cgtagttttg tgccgtatcc tattcgctat atatggactt gttatcaggc tttgggttat
    14161 attagagaag cctatcaaac actagcgcgt aaggaactaa cgatggaagt cttggactgt
    14221 tcggctattt tattgtcttt gtttatgaac caatccaaga cagctagcaa tatcatgttt
    14281 atgcttgatt tggggaatca tttagatcag tggtccttga aaaaaactgc aacagattta
    14341 gaacagagtc ttcttgcaaa agagagcgat gtattcctag tacagggcga tacagttgtt
    14401 agtatcaaga gttccgatgt tcaaatagga gatgtcttga tcttatctca aggaaatgaa
    14461 attctgtttg atggacaagt agtttcaggt ttaggtatgg tcaacgaaag ttccttgaca
    14521 ggagagagtt ttccagttga aaaaagagag tctgatttgg tttgtgcaaa tacagtatta
    14581 gaaactggag agttacgcat ttgtgtaaca gataatcaga tgaacagccg tattttacag
    14641 ctgattgagt tgatgaagaa atctgaagaa aacaagaaaa cgaaacaacg ctatttcatc
    14701 aagatggcgg ataaagtcgt caaatataat ttcttggggg ctgggctgac ttacctattg
    14761 acaggttctt tttctaaggc tatttctttc ctattggtcg atttctcctg cgctttgaaa
    14821 atctctactc ctgtagctta tttgacagtt atcaaggaag ggttgaaccg tgaaatggtg
    14881 attaaggatg gagatgttct ggagaaatat ctggaagttg atactttctt gtttgataag
    14941 acaggaacaa tcacaactag ttatcctata gttgaaaagg tgttaccttt tggagactat
    15001 agtgaggaag atattctcag aatcagtgcc tgtcttgagg aacacattta tcatcctatt
    15061 gctaatgcca tcgtcaagca agctgagata gagggaattg aacatgagga aatgcatggg
    15121 aaactccaat atatcgcaag caaggggatc aaatctcata tagatggcca accagttctt
    15181 attgggaatt atgtcttgat gcaggatgag cagattcata tcagttcaga acaaaatgct
    15241 ttaattgaag agtacaagag tcactacaat ctcttattct tggcttatca aaatgaattg
    15301 attggaatgt tctgcattca tactcctttg agaaaagaag caaaaacagc cttggataaa
    15361 cttaaggcac aggggaaaaa attgattctg gcaacaggag acaccttgat taggacagag
    15421 gaattagtca aagatttgcc ctttgatcag gtctatacag acttgaaacc tgatgggaaa
    15481 tttgagttag tagagaaact gcagaaagca ggtcacacta ttttgatggt tggagatgga
    15541 ttgaatgact cagcggcttt aactctatca gatatcggtg tggtgatgaa tgagagtgca
    15601 gatatttcta agcagatgag tgatatctta ttgttagata atcgtttgga tttcttccaa
    15661 gagttggatt cgttatcatc atctttgcaa acactcatca agaaaaatat tcaggatacc
    15721 gttgtcgtaa atagtagttt gattggcttt ggcttattta attggttcag tccttcaaat
    15781 ctctctatct tacataatct aacaaccttg cgcattgtcc tgcgtagcct gtctattaaa
    15841 aatagataga tgagagttat taacagcaaa aaggagttac ctttctcgag gttaactcct
    15901 ttgtttatag ataaatgttg aatagtttag taagtcaata caaagtattt tttcttccca
    15961 cgacggataa cagtcagttc attttctaac ttatcagcgt cactcaagac atagtcaagg
    16021 tcttggatgc ggtcgccgtt tacgtagatg gctccgtttt ggacgtcttc acgggcttgg
    16081 cgttttgagt taactatacc agatgagacg agcagttcca cgatattgtt gttttcgtct
    16141 gcctgtactt ggtagtttgg cacaccacga agtccttgtt tgagctcttt gacagaaagg
    16201 tttttgatgt ttcctgcaaa gagttgctca gtgatgttaa gtgcttcttt gtaggcttct
    16261 tctccgtgaa caagtgtaac aacttcacga gccaagactt tttgagccaa gcgttcgtgt
    16321 ggcgctgctt caaattgttt acgaatatct tcaatctcat caagtgacaa gaaagtaaag
    16381 attttcaaga agcgaacagc gtcagcgtcc atcacgttca tccagaattg gtacatttcg
    16441 tatggagaag tcttttcggg attgagccag acggcatttc cttctgattt accaaatttc
    16501 ttaccagttg catctgtgat tagtggaaca gtgataacgt gaccagtctt gtccgcctta
    16561 cgacgaagca attcggtacc agctgtcata tttccccact ggtcagaacc accgatttga
    16621 agagtgacat tatggtcttg gttaaggacg aagaagtcgt acccttgcat gatttggtaa
    16681 gcgaactcag tgtaagaaat tcctgtttcg atccgttttt taacagattc cttactcatc
    16741 atgtagttga ccgtgaagta ttttccaata tcacggagga agtcaatgaa gctgatgctg
    16801 ccaaaccagt cgtagttgtt gaccatgaca gccttgtttt cgccattttc aaagtcaaga
    16861 aaacgagaaa gttgtccttg gatagacttg acccagccat ctactgtgtc ttttgtttgg
    16921 agactacgtt cagcatcttt gaaggacgga tctccgatga gacctgtagc accgccaacg
    16981 agcgcataag gtttgtgacc tgctagttgc aagcgacgac ttgtcaagat tgcgacaagg
    17041 tggcctaggt gaaggctgtc agcagttgga tcgtagccag tataataaga aacttgacct
    17101 tcttctaggg ctttacgcaa agcttcttca tcagtcgttt gaaatatcaa accacgctct
    17161 tttagctcat caaaaatgtg catgtgtctt ttctcctttt taaaattatt gtttctacct
    17221 attgtatcac aaacttgggc aatagcctag cagaataggg aagaaagtgg ctattttatt
    17281 gaaaatttcc cttttgtggt ataatagata gagtgaggaa atccatgcaa aatcaattaa
    17341 atgaattaaa acgaaaaatg ctggaatttt tccagcaaaa acaaaaaaat aaaaaatcag
    17401 ctagacctgg caagaaaggt tcaagtacca aaaaatctaa aaccttagat aagtcagcca
    17461 ttttcccagc tattttactg agtataaaag ccttatttaa cttactcttt gtactcggtt
    17521 ttctaggagg aatgttggga gttgggattg ctttggggta cggagtggcc ttatttgaca
    17581 aggttcgggt gcctcagaca gaagaattgg tgaatcaggt caaggacatc tcttctattt
    17641 cagagattac ctattcggac gggacggtga ttgcttccat agagagtgat ttgttgcgca
    17701 cttctatctc atctgagcaa atttcggaaa atctgaagaa ggctatcatt gcgacagaag
    17761 atgaacactt taaagaacat aagggtgtag tacccaaggc ggtgattcgt gcgaccttgg
    17821 ggaaatttgt aggtttgggt tcctctagtg ggggttcaac cttgacccag caactaatta
    17881 aacagcaggt ggttggggat gcgccgacct tggctcgtaa ggcggcagag attgtggatg
    17941 ctcttgcctt ggaacgcgcc atgaataaag atgagatttt aacgacctat ctcaatgtgg
    18001 ctccctttgg ccgaaataat aagggacaga atattgcagg ggctcggcaa gcagctgagg
    18061 gaattttcgg tgtagatgcc agtcagttga ctgttcctca agcagcattt ttagcaggac
    18121 ttccacagag tcccattact tactctcctt atgaaaatac tggggagttg aagagtgatg
    18181 aagacctaga aattggctta agacgggcta aggcagttct ttacagtatg tatcgtacag
    18241 gtgcattaag caaagacgag tattctcagt acaaggatta tgaccttaaa caggactttt
    18301 taccatcggg cacggttaca ggaatttcac gagactattt atactttaca actttggcag
    18361 aagctcaaga acgtatgtat gactatctag ctcagagaga caatgtctcc gctaaggagt
    18421 tgaaaaatga ggcaactcag aagttttatc gagatttggc agccaaggaa attgaaaatg
    18481 gtggttataa gattactact accatagatc agaaaattca ttctgccatg caaagtgcgg
    18541 ttgctgatta tggctatctt ttagacgatg gaacaggtcg tgtagaagta gggaatgtct
    18601 tgatggacaa ccaaacaggt gctattctag gctttgtagg tggtcgtaat tatcaagaaa
    18661 atcaaaataa tcatgccttt gataccaaac gttcgccagc ttctactacc aagcccttgc
    18721 tggcctacgg tattgctatt gaccagggct tgatgggaag tgaaacgatt ctatctaact
    18781 atccaacaaa ctttgctaat ggcaatccga ttatgtatgc taatagcaag ggaacaggaa
    18841 tgatgacctt gggagaagct ctgaactatt catggaatat ccctgcttac tggacctatc
    18901 gtatgctccg tgaaaagggt gttgatgtca agggttatat ggaaaagatg ggttacgaga
    18961 ttcctgagta cggtattgag agcttgccaa tgggtggtgg tattgaagtc acagttgccc
    19021 agcataccaa tggctatcag accttagcta ataatggagt ttatcatcag aagcatgtga
    19081 tttcaaagat tgaagcagca gatggtagag tggtgtatga gtatcaggat aaaccggttc
    19141 aagtctattc aaaagctact gcgacgatta tgcagggatt gctacgagaa gttctatcct
    19201 ctcgtgtgac aacaaccttc aagtctaacc tgacttcttt aaatcctact ctggctaatg
    19261 cagattggat tgggaagact ggtacaacca accaagacga aaatatgtgg ctcatgcttt
    19321 cgacacctag attaacccta ggtggctgga ttgggcatga tgataatcat tcattgtcac
    19381 gtagagcagg ttattctaat aactctaatt acatggctca tctggtaaat gcgattcagc
    19441 aagcttcccc aagcatttgg gggaacgagc gctttgcttt agatcctagt gtagtgaaat
    19501 cggaagtctt gaaatcaaca ggtcaaaaac cagggaaggt ttctgttgaa ggaaaagaag
    19561 tagaggtcac aggttcgact gttaccagct attgggctaa taagtcagga gcgccagcga
    19621 caagttatcg ctttgctatt ggcggaagtg atgcggatta tcagaatgct tggtctagta
    19681 ttgtggggag tctaccaact ccatccagct ccagcagttc aagtagtagt tctagcgata
    19741 gcagtaactc aagtactaca cgaccttctt cttcaagggc gagacgataa ttctctaaat
    19801 gaagtggcca atcaatggat tgccactttt ttcctttcgt gttacaataa gggtatgaat
    19861 cagtatcaga aaaagattgt taacggaaaa atttattcgc tcctatccgg cttaatatgg
    19921 ggaatctgtg gaattttagg agagtacttc tttactcatt atcaggtgtc ttcgggctgg
    19981 attacctcta tgcgtttgac actggcaggg agtcttgtac tcatttggtc tgcaatacaa
    20041 ttaaaatcgc aagtgctaga tatttggcga gacaagaaaa attacctgcc ctttttagcc
    20101 tatgctattt tggggatttt ttcagttcag tattttttct atctctgtgt agaatactca
    20161 aatgctacga cagcaactat tttacagttt attagccctg tttttatcct cttttacaat
    20221 cgcttggttt atcaaaaacg agcgtcaaaa agcgctgttt tctatgtttt ggttgccatg
    20281 ctgggtgttt gcttgatggc gacaaaggga gatctctctc agttatccat gacgccgcta
    20341 gctcttataa caggtttgct gagtgccatg ggtgttatgt ttaatgttat cttgccccaa
    20401 ccttttgcta agcgttatgg ttttgttcct acggttgggt gggggatgat tttggcaggt
    20461 ttgtttagca atgtcctctc gccggtttat cagctttcct ttactcttga tatttggagt
    20521 atcttgattt gcctcattat cgctttcttt ggaacggctt ttgctttttt catttccatg
    20581 aaggctgtgt ccttggtttc tcctttggtg gttgccgtta tcagtgccag tgaacctctc
    20641 tcttctgctc tcttgagtgt tttgttctta ggattagtag tggattggtc cctccttcta
    20701 gctatagcct tgattatttt acccatgata tttttgtcta tagaagaagc gaaagaaagt
    20761 agataaaaag tcttttctta attctaaaag tgtgctatac tagaatagtc aataaaacac
    20821 ggggagatag ttgtgaagag tgtttttagg ttgtatcggt aggggcttgc ttttaccgac
    20881 agcacgtttt atctcacatc cctaaaaaat catacctaaa aacagacaaa aaggtttcaa
    20941 atttgaggcc ttttttggta gaataggtat cattataacg aaccaggagg cacctatgac
    21001 tgctacaaaa atgaacgctc aagaaattat ccaatttatc gccaatgctg aaaagaaaac
    21061 cagtgtcaaa gtaacctttg aggggcaact cgcaactgct gtgcctagct ctgttgtcaa
    21121 actaggaaat gtcctattcg gagactggaa ggacgtggct ccgcttcttg aaggtttggt
    21181 agaaaatcaa gattatgttg tcgagcaaga tgctcgtaat tctgcagttc ctttgctaga
    21241 taagcgtgct atcaacgctc gtatcgagcc aggtgctatt atccgtgacc aggtggaaat
    21301 tggtgacaat gctgttatca tgatgggagc tgttatcaat atcggtgctg aaatcggtgc
    21361 tggaaccatg attgacatgg gtgccatcct tggtggccgt gctatcgttg gaaaaaatag
    21421 ccacgttggt gcaggtgcag ttttggcagg tgtgattgag ccagctagtg ctgaaccagt
    21481 ccgtgtcgga gacaatgttc ttatcggtgc taatgcagtg gttatcgaag gagtccaaat
    21541 cggtagtggt tcagttgtcg ctgcaggagc tatcgttacc caagatgtcc cagaaaacgt
    21601 ggtagtagca ggtgttccag ctcgtatcat caaagaaatt gatgcccaaa cccaacaaaa
    21661 aacagcgcta gaggatgcgc ttcgtacctt gtaattgtaa aagtaaaaaa gaggcggaac
    21721 cctttttcca gcctctttct gctatatcgg aggacagata gatgttagat ttgattcaga
    21781 ctagacgagc tttacaccag attccagaga ttggcttgga ggagttcaag actcaggctt
    21841 atttgctgga tgtgattgag aaattgacta cgggcaagga ttttgttcaa attcgtactt
    21901 ggcggacagg gattttggtc tacctgcagg gaagtcagcc ggagcgaacc attggttggc
    21961 ggacagatat tgatggtctg cctatcgtcg aacaaacagg tctacctttt gcttctcaac
    22021 accaaggtcg catgcatgcc tgtggccatg attttcatat gaccattgcc ttaggctgtc
    22081 ttgagcgcgc ccttgaggag caacccaaga ataatctgct ctttctattt cagcctgctg
    22141 aagaaaatga agctggtggt atgctcatgt atgaggacgg tgcttttgga gattggttgc
    22201 caaaccaatt ctatggtctc catgttcgtc cagatttgaa agtcggccag attgcgacta
    22261 atactcatac actctttgca ggaacttgcg aggtgaagat ccgtttcaaa ggcaaaggtg
    22321 gccacgcagc ttttcctcat gaagccaatg acgccttggt ggcggctagt tactttgtga
    22381 cccaagtgca gtcagttgtt agccgcaatg tcaacccaat cgagggagca gtggtgacct
    22441 tcggcgtttt tcaagctgga accaccaaca atgtcatcac agacacagct tttttacatg
    22501 gaactattcg tgccttgaca caggacatga gtctcttggt gcaaaagagg gtaaaaacag
    22561 ttgcagaagg ggttgcagct gcctttgata tggaagtcga agtggaactc aaacaaggtg
    22621 gatacctacc tgttgagaac aatccagcct tggcgcgtga actgatggac ttctttgacg
    22681 aaaaagacgg aatcgagttg attgatatcg aacctgctat gacaggcgag gactttggtt
    22741 atctcctttc aaaggttgat ggcgtgatgt tttggctagg tatcgatagt ccctacgctc
    22801 ttcatcaccc tcaaatgagt cctaaggaag aagtcttagc tattggggtg gctgcggtgt
    22861 ctagtttcct gaaaaagaag gcagcagaat agagggcttg tctatgaaat cggaattacg
    22921 caagcaagtc ttgcatgaaa tgaaggcttt atctcaagaa caaaaacagg ctatagacca
    22981 agctttaacc gagcgaattt tacaacaccc cttttatcaa gaagccaagg tcatcgcaac
    23041 ctacctctct ttttctcatg agtttcaaac gcgggaactg attgagcagg cgctgaagga
    23101 cggcaagaag gttttaatac ccaaaactta tcccaagggg cgcatggact ttgtagtcta
    23161 tgatccgcag cagttggtaa aaactgcctt tgccttactg gagccacagg gagatttgga
    23221 agtggtggat gtatctcaga ttgatttgat tcatgttcct ggcctggctt ttacgacgga
    23281 tggatatcgg attggatatg gtggaggtta ttatgaccgc tatctggaac atttttctgg
    23341 tcatactttg agtacggttc atccttgtca aattcaggac tttatacctg aaaaccatga
    23401 tattcctgtt caggaggtat taattgatga aggaaatctt tgatagacgt taccctgtga
    23461 cgagtttctt cctcttagtg acggccttgg tatttttact aatgttggtc actgcaggcg
    23521 gaaactttga cagggcagat acattatttc gatttggagc catgtatggg ccagctattc
    23581 gcctctttcc cgagcaggtt tggcgtctct tgtctgccat ttttgttcat attgggtggg
    23641 aacatttcat tgttaatatg ctttcacttt attatcttgg aaggcaggta gaggagattt
    23701 tcggctctaa gcagttcttt tttctctatc tcttatcagg aatgatgggc aatctctttg
    23761 tttttgtatt tagtcctaaa tccttagcag caggcgcctc tacctctctt tatgggctat
    23821 ttgccgcgat tattgttctt cgctatgcaa ctcgcaatcc ttatatccaa cagctagggc
    23881 aatcctatct gacacttttt gtggttaaca ttattggaag tgttctgatt ccaggaatca
    23941 gcctagcagg ccatatcggt ggtgcagttg gtggcgcatt tctagcagtt atctttccag
    24001 ttagaggaga aaaacggatg tataatacca gccagagatt aggagcggta gtcttgttcg
    24061 taggactcgc cattttgctt ttctacaagg gaatgggaat gtgacgaagt tgaaagaaaa
    24121 tttgtgtaat gaaaaaagat aaggcatttt ttgaacctta tctttttatt ttattccttc
    24181 tcagtcaatt cttttccaag ttggatgagg taattcttca aatcatcttt gacttgtggg
    24241 tgtttgaggg cgtagtcaat agatgttttc ataaagccaa acttatcccc aacgtcgtaa
    24301 cgagctcctg taaattcacg ggcaaaaaca cgctgtgttt tattaagagt atcgattgca
    24361 tcagtaagtt ggatttcatt tccagcacca ggagcttgct tttcgagaat ctcaaaaatt
    24421 tcaggcgtga ggaggtagcg tccgataata gcaaggtcgc taggagcgtc ctctggagct
    24481 ggtttttcaa caaaggtttc aacactgtaa agaccatctt ttccttcgcc ttgcggagca
    24541 ataaccccgt aagcagatac ttcgtcatga gggactggca tgacagcgat agtagacgcg
    24601 tgggtacgct tgtagtcatc catgagttgt ttggtaagtg gaacagcctt ttcgtctgtg
    24661 atatccatca agtcatcacc aagcataacg acaaaaggtt catttccgac gaaagccttg
    24721 gcttgcaaaa cagcatctcc gagaccgcgt ggatgagttt ggcggataaa atgcagacgc
    24781 atgccagttg tttcatcaac tagcttcaaa agatctgttt tccctttttc tttgaggtta
    24841 tattccaatt cgaagtttga atcgaagtgg tcctcaatag aacgttttga tttaccagtg
    24901 acaactagaa tatcttcaat acctgatttg agagcctctt ccacgataaa ctggatagtt
    24961 ggtttgtcta cgattggcaa catttctttg gcaagggcct tggttgctgg taaaaatcga
    25021 gttcctagtc cagcagcagg gataactgcc tttctaactt ttgatgtcat aaaaatcctt
    25081 tctatagagg gttaagacca ctcattttct gctttaaatt cattgttcat gatgtcataa
    25141 atggcatctt tgatattggt tccgtgataa ataacttggt aaatagcctg tgtaatgggc
    25201 atatagactc caagttcttg ggctagttca taggctgctc gagtcgttga aattccttcg
    25261 attaccatgc ccatattagc ttctatatca gctagggatt ctcctcgtcc gagagcatct
    25321 ccagctctcc agttacgaga gtggatggaa gttcccgtta cgatcaaatc tcccacacca
    25381 gataagccgc tataggtcaa tggactggcc ccgagtgcta cccctaggcg ggtgatttct
    25441 gctaaacctc gagcgatgat ggctgcctta gcattatcac caaatccaag accatgtaaa
    25501 gctccagcac cgacagcaat aatattttta agagcaccag cagtttcaac cccgataaca
    25561 tccgtattgg tataaagtcg gaagtagtga ttactaaata gctcctgaac gtattgagct
    25621 gtttgtaaat ctttagaagc agcagttatt aaagttaggt cacgcacaat ggtctcttct
    25681 gcatgactag gccctgaaac aacgacgata tcactacgga gatgttcagg aatttcttct
    25741 tcaagaatgg ttgataatcg tttatggcta tcaggttcta atccctttga tgcgtgcatg
    25801 atgataacct tatggtccaa ggtttgtgca acttgctggg caacaagtcg tgtcactttt
    25861 gttgggacaa caaacaaaat cgcatccaca tttttcaatg tttctgctaa gtcggtgtag
    25921 gcaatgatat tttcgtctag aacgacatct ttaaagtagt gcttattagt atggtgtgta
    25981 ttaatttcat tgatttgctc gggaagattt ccccaaatac gtatctcgtg tccattgtca
    26041 tttaagactt gtgaaagggc ggttccccaa gaaccaggcc ccaagacggc gacggtttgt
    26101 ttttccatga tttcctcctt gatagatttc tttctcttat tctatcatat tctaggggat
    26161 tttgcacttg cattactggg gtatggtgga aaaatacaca aaaaccgaga cgaagggata
    26221 aactcttagt ctttagttaa agtgagaaga aatctgatag atagtttgat tcagtatatg
    26281 cttataatag aggtaaacaa ctcaggaagt tcttgtaggt tgcgagagtt tggcaaaaaa
    26341 attaaaagat tacgtttggc taaaaaaatc agtcgttcag aattttgtgg tgatgagtct
    26401 gaattaagta tccgtcaatt aattagaatt gaaaatggag aatccagacc aatactaaca
    26461 aagttaaaat atattgctga acgtttgggg gttgaagatt acaagttgat gccaagttat
    26521 atagagttgg ataaggaata cctagaattg aagtatttct tgatgaggat tcctacatac
    26581 gaagatgaaa ctatcgccca aaagaaagag agtgttttga taagattttt gaagagtatt
    26641 atgataggtt acctgaggaa gaaagattta tcatcccaaa ttattcatat ctggcactaa
    26701 cgaactacac agttcaaaaa ttaccagaaa agctagttga aatactgtcc ttctggtgat
    26761 tttgcttaat ttctgatgtt cgagacataa ttgaggagat ttgtcttgat tttttcctaa
    26821 aaaagggcag actcctccct tggtttgatg ctcgattttt aaaataaggt gacttattct
    26881 gttaggcatg ttttcccctg ccctctagct ctatatggaa cagggagtat cagatttatc
    26941 tggcagattg tatcaaataa ggcttgaaac tgttttgaat aggcgtatag acttgagaat
    27001 ttgagaatat gtcgtctagc agtagagaca tattttccgg caatatgaag gaagagacgt
    27061 cgaaaacgct tgatagtcaa ggactttact tcatcaccag ctagctgctt taaaaagagg
    27121 tagagattat aagccagaca gcccatcatc atacgtactt cattcttaat catggtcgaa
    27181 ctatctgtct tatccccaaa gaatcctgct ttcctttctt tgataaagtt ttcagcattc
    27241 cctcgttcac gatagaattg aaacagctcc tcactatcta cactgcttaa attggtcaaa
    27301 ttggtcaaat gaactttttt acaaccataa aaaagagcac ttaatcgtac tcttctcttt
    27361 taaggattag ttgaattaat tcaaatccac tagttctcct gtttctaggt agactaggcg
    27421 ttcacaaatg ttagcaatgt aatcagcgaa gcgttccaga tgccctatga tataaaggta
    27481 ttgagttcca ttgggaattg aggtttcttg gtctttcata agtccaatga tttcctttga
    27541 taaggcataa taatattggt caatctgttc atctttttga gcaatactaa tagcttttga
    27601 ggcttggtgc aaaggaaagg caaccaataa atcggctagc atgttgaggg ataatttacc
    27661 catttggtgt aactgttctt cgtcaggggc tagttgattt tcttttagtt gcaaaacagc
    27721 tttggcaatg cctgccatat ggtctcccat acgttcaagg tctgaacaag aagacatgat
    27781 gctaatcaca aatcgaaggt cagacacttg tggctgctgc aaggccaaca aacgggcaca
    27841 ggtcaattcg atagcgcttt gaccttggtt gatagcatga tccttattga taattagctc
    27901 tgccatctcc ttgtctttgg aggctaaggc cagtaaggct tttgaagctg tttcaaggac
    27961 aagttgccct agtcctaaaa aggattgttc taattcatgc aattctaagt caaattgatt
    28021 tctcataggt ttttccttcc ttatccgaac cgtcctgaaa tatagtcttc tgtgcgctga
    28081 tcttttggat tggtaaacac gtcaacggta tctccaaatt cgcaaatttc tcctgttaag
    28141 aaaaaagcag ttttatctga aatacgtgaa gcttgttgca tgttatgggt aacaatgata
    28201 atcgtataat ccttttttag ttgctgaatg aggtcttcaa tttttaaagt ggagataggg
    28261 tctaaggctg aagtcggctc atccattaac agaacatcag gttctactgc taaagctcgc
    28321 gcaatgcaaa ggcgttgctg ctgaccgcca gataaggaca tggcactctt tttaagatca
    28381 tctttgactt cttcccaaat ggctgcccct tttaaagatt tctccactaa ggcatctaat
    28441 tgttttttgt ctcgaatacc atgtgtcctt ggaccataag ccacgttatc atagatagac
    28501 atggcaaagg gattaggctg ttgaaaaacc atccctacac gcttgcgtag ctgattaagg
    28561 ttgaatttgc tactataaat atcttgctca tctaagagga cttggccttc aatatggcaa
    28621 gaaggaacca aatcgttcat ccgattaagg gtttttagaa aagttgattt gccacaacca
    28681 gatgggccta tcaaggcagt aatctgtctt tctggtaatt gaatcgaaat attttttaag
    28741 gcttgaaaat ccccgtaaaa taagtctagg tgtctgactg aaaatgttcc catactagga
    28801 agctcctttc acaagtttcc gagataataa gcttgataga gtatttatca ttaaaacagt
    28861 aataatcaaa atcacgccgg tagcataggc ttcattgaca tgtagcccct cacttgacag
    28921 catatacata tgtagggcta gagaacggcc tgaagacatg agactacttg gcgtattggt
    28981 agaggtacct aatgtataca tgagggcagc tgtttcacca acgatacggc caatagctag
    29041 tatcactcca gctaaaatac ctggcatggc aactggtaga acaattctaa aaacagtccg
    29101 taacttacct gccccaagtc cataacttgc ttgacgcatg ctatcactaa cagataaaag
    29161 ggcttcttct gttgagcgaa taatgactgg caacaccatg ataactgagg ttaagattcc
    29221 tgataacaga gagtattgaa aacctaagaa gactacaaag aagagcatgc caaacagacc
    29281 aaaaacaatg gaaggaatcc cagacaaggt atctgaggcc aatcgcatga ttttaacaca
    29341 aagggaatct ttttttgtat attccacaag ataaaaacca gcaaaaatcc ctatgggcaa
    29401 ggctaaaaga agagcaccaa aaaccagaat aacggtggaa ataatcgctg gcataaggga
    29461 aatgttctca gaagtataag tccaagaaaa gagggataga cttagatgag gtaagccttt
    29521 gatgaggata aaaccaatga ttaaaaagag agagccaaag gttaaagctg aaaaacaata
    29581 aacgagaagt tttagcaggt atttactcat aagatgattt tcctttcaag taggcaaagt
    29641 aggcattaat caagagaata aggaaaaaga gaactgctga ggttgcaata agggcttccc
    29701 tatgctgacc tgatgcgtaa gccatttcca gaacaatatt ggttgttaag gttctggttc
    29761 ctgaaaagag tccacttgga ataatcggct ggttgcctgc caccaaaata actgccatgg
    29821 tttcacctac tgcgcgacca attcctaaaa taactgctga taaaatacca gatctcgcag
    29881 ctggcaagat gacactaaaa atactccgtt catgactagc tcctagagcc aagctaccag
    29941 aataatacgt tttgggaact gttcggatag cagattctga caaactgata atggttggca
    30001 aaatcattat tcctaatagt aacgaagcgg ttaggacact catgccattt cctaaaaagc
    30061 ttctaatcca aggcaccaat aattgtaggc cgaaaaaacc ataaacaata gatggaatgg
    30121 ccgccatcaa gttgatagct gattttaaga agccatagac gggctttgga caataataaa
    30181 ccataaacac tgatgtcaag atgcctgttg gcaccccaat cacaatcgct cctaaggtaa
    30241 ttaataagga accaacgatc attggtaaaa taccatagct tgccggaatg ttcgttggcg
    30301 accaatcact gcctaataaa aaacgggcaa agccgtagtt agccatgaaa ggtaagccat
    30361 tactaaaaat aaagaaacag attagcaaaa tagctacaac agctactgtt gcactcatga
    30421 aaaaaattgc cctaaaaact gcttctttga aggcttgttt tgtcacatct tgtcctttct
    30481 agtgaagaaa gtaagggaga tacgacacct ccctacttgc cttctttatc ttattgtacg
    30541 atgaaacgtc tgcatctctt tagagattta tggagcaaac attttattta atcttgtccc
    30601 aggtggttaa tttgccacta aaaacgtctg caagttcagc catactgact tggcttgcct
    30661 tattgtcatt attgaccaca acagcaatac cgtctaaagc aatagcatca tgggtgagac
    30721 tcttaccttc ttcaggagtt aattccctag aaaccatacc aatatcagcg gttttctcct
    30781 taacagcggt aatacctgct gaagacccat tagaggtaat atcaatcgta acttctggat
    30841 tttctttttt ataagcttct gctaattttt ccattaaaga agatactgaa gtggaaccta
    30901 caacagacaa cttgcctgat aagtgttggc ttgtatattc tgtggtttcg gttttagctt
    30961 caataaattt attatctgtg accacttgtt gaccttgttt ggagtggata aagctgataa
    31021 aatcttgacc tagcttggaa agattagaag accaaacaat gttgaaggga cgttgaagag
    31081 ggtattcacc atctaaaact gtgtctcgac tagccttgac accatcaatc tctaaagcct
    31141 tgacagattt cgttaaagat cccaaggaga tgtagccgat agcattagca ttcccttgaa
    31201 ctgctgagag aacaccttct gtactatttt gaatcacagc tgttttggca gtgttgtcaa
    31261 tttttttatc accgtctttt ttgagaatcc ctgtgatttc tgtgaaggca ccccgtgttc
    31321 cagagccatt ttctcgtgaa atcacctcaa tcgttcctga agctgactgt ttggaagcag
    31381 ctgactgatt gccacaggca acaagcccaa atcctgataa gccaatggct gcaagagtaa
    31441 gcattttttt gaatttcata ataatcacct ttatctctat gtatttttct tgtgtaggct
    31501 tactacattt atagtctaac aagtctttgt aaaggtttat ccctgattca tgtaaagatt
    31561 gtgtaaagaa tcaaaaaaag ccacttttga aaaatggctg ctcctaaaaa tagctttaaa
    31621 aattattagt cctgtgcgaa agattggtta ggaagaaaaa tcgtgaagca actgcctctg
    31681 ccaagctgac tcgtcaccgt gacttggcca cctaataatt gactgagttc tttgacaatg
    31741 gcaaggccaa gaccagtgcc accagtttgt ctgcttcgac ctttattaac tcggtaaaaa
    31801 cgttcaaaaa tacgatcctg ctctaattga ctaataccaa tccctgtatc tgatacagaa
    31861 atcttaatgc cttcgttccc cttttgggtc ttgacctcaa tttttccccc ttgttcagtg
    31921 taacggatgg cattggataa aagattgagt aagatttggg aaagtaattg actatctgat
    31981 acgagggtga catcatctgg cacctgcacc tttagctgta aatccttctt cttgagctga
    32041 ggttgcaagc tttgagtcaa atcctgtaca aattctgcca aagaaagggt cgtccattgt
    32101 ataggcattt gttgagcctt agataaggta agaagatgct caacaatatg ctcaagacgc
    32161 aaactttctt tgtaaataat gtctagaaag tcatccttga gcgcttcttc ttcagctgac
    32221 atccccttaa tggtttcagc aaagccctta atcgaagtaa ctggtgtcct caattcatgg
    32281 gaggcatttg agacaaaggc taaatttaac ttttcataag ttctaatcgt tgttaaatca
    32341 tatagcaaga cgagcacagc ttccacagat tgggtggggc taaaaacggg aactgctgtc
    32401 acttctaaaa tcaagtcacc ctcatgaaac ccacttactt cttgttttaa ccttgttttt
    32461 tgatcaaagg cttggtgaac taaatttcga atatccatcc gtttgaggtc atcaagtgaa
    32521 cttatgtcgc cgtccacatc gggaaaataa tgaggcagag agcgactgga taataacatc
    32581 tgaccttgag cggaaactaa aaacgtcccc atggttaggt gcgacagaag aacctccatt
    32641 gtttcggcta gatccttgta ttgctgatcc tgttgggaga ctttggtttt taggccagac
    32701 acatactgag ccaaagactt taagtcttct tgcccttttt ctaaaaagta ttcactactg
    32761 gtcaagagag gttggtgcaa ggtctcaaaa gcaacttccc atttccaaag gcaaaagagc
    32821 cagtagccac ctagtcccaa agaaagggct agaagaaaga gaccgatgcc tttactgatc
    32881 caagttaatg ccatccctgc aatcagaatg aggctaacac ttagattgac tagccaaaat
    32941 tgaaggtagc gtttcatcta taactccttg aacttataac cataaccccg aatggttcga
    33001 ataaattgag gggctttagg attgtcttca attttttccc tcaacttacc aatatgaacg
    33061 tccaccaaac gtgtttcctg cccaaagtca tacccccaga tacgttccaa aagacgctct
    33121 ctagtcagtg tcatgttggg atgtttcata agatagagca agagttcaaa ttcttttggg
    33181 gtcaaactca gtaacttatt cgccttgtag acttcatgac gctcagggta tactttcaag
    33241 gtcccaaata gccaagaatc gtcagcgata ttatctgaat catctccttc ttgttctcct
    33301 ttagttcgcc tgaggacagc cttgacacgc gccagcaatt ctctagggct aaaaggcttg
    33361 gtcaggtagt catcagcccc taattccaag gccaaaacct tatcaaattc atcacttttc
    33421 gcagaaacca tcataattgg agttttgacg cctttggctc tcagccgctt acaaacttcc
    33481 atgccatcta attgtggtaa catgatatca agcaagataa aatcaaaggg ttctgtttct
    33541 gccaaagcta aggccttccg tccatttgtc accaattgag tagaaaagcc ttccttactt
    33601 aaatggtagt caagcaattt cagaatgtgt tcttcatcat ccactaataa gacttgtttt
    33661 gtcatctatt atctcctatt ggtaacatta taacacaatt atcagaaatc ctaacattgc
    33721 taaatcagat taaatttgcc tatcaagact agtatctggt caaacgctca atcatctcct
    33781 tgtgctctgg ataggtcgcc agtagatcta ccctttcaaa taattcaaaa tcctcaaatt
    33841 caaaaccagg agcaacaaga caagaaacca gagcatcatc cttatcaact gttgatcccc
    33901 aaatagtgcc cttaggaaca cagtagtgaa gttgttgccc tttggatatg tccaggccta
    33961 aagtgactgc ttcgtagtga ccatctgctg taatcatgtg aacagtaagt ggggatcctg
    34021 catgaaaata ccagatttca tctgctgtca atcggtgaaa atgtgaagga ttcgtttctt
    34081 ctaataagaa ataaatactg gtataaagcg cccttccctt accagcaagg tttatagtgt
    34141 ctgaagcttt ttttgtttgt ctaaaatagc caccttcaac atggggagct aactctagag
    34201 ttcttatcaa gtcttcttta tccgtcggag ccaatgggt
//
LOCUS       DBERPV010000018        34121 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.18, whole genome shotgun sequence.
ACCESSION   DBERPV010000018 DBERPV010000000
VERSION     DBERPV010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 34121)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34121)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34121
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.18"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..935
                     /gene="phtB"
                     /locus_tag="ACL8C7_001166"
     CDS             <1..935
                     /gene="phtB"
                     /locus_tag="ACL8C7_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HGS1395377.1"
                     /translation="QITYTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHM
                     THSHWIKKDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKK
                     VPLDRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVK
                     YYVEHPNERPHSDNGFGNASDHVQRNKNGQADTNQTEKPNEEKPQTEKPEEETPREEK
                     PQSEKPESPKPTEEPEEESPEESEEPQVETEKVEEKLREAEDLLGKIQDPIIKSNAKE
                     TLTGLKNNLLFGTQDNNTIMAEAEKLLALLKESK"
     gene            1283..1357
                     /locus_tag="ACL8C7_001167"
                     /pseudo
     CDS             1283..1357
                     /locus_tag="ACL8C7_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397816.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
     gene            1357..1737
                     /gene="dhaM"
                     /locus_tag="ACL8C7_001168"
                     /pseudo
     CDS             1357..1737
                     /gene="dhaM"
                     /locus_tag="ACL8C7_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
     gene            2196..2909
                     /locus_tag="ACL8C7_001169"
     CDS             2196..2909
                     /locus_tag="ACL8C7_001169"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HGS1395378.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYDLYAATNGITAIQTGRLAQSGLVPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            2923..3570
                     /locus_tag="ACL8C7_001170"
     CDS             2923..3570
                     /locus_tag="ACL8C7_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395379.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNKAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCIGDFPHDFFDIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRFFSN
                     FDDFLEKNYLKTIWQVSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            3706..4359
                     /locus_tag="ACL8C7_001171"
     CDS             3706..4359
                     /locus_tag="ACL8C7_001171"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HGS1395380.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            4369..4833
                     /locus_tag="ACL8C7_001172"
     CDS             4369..4833
                     /locus_tag="ACL8C7_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HGS1395381.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGM
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            4846..6114
                     /locus_tag="ACL8C7_001173"
     CDS             4846..6114
                     /locus_tag="ACL8C7_001173"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HGS1395382.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            6128..6388
                     /locus_tag="ACL8C7_001174"
     CDS             6128..6388
                     /locus_tag="ACL8C7_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395383.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            6399..7760
                     /gene="pdrM"
                     /locus_tag="ACL8C7_001175"
     CDS             6399..7760
                     /gene="pdrM"
                     /locus_tag="ACL8C7_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HGS1395384.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGIPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDNIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKC"
     gene            7914..8882
                     /locus_tag="ACL8C7_001176"
     CDS             7914..8882
                     /locus_tag="ACL8C7_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HGS1395385.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            8898..9890
                     /locus_tag="ACL8C7_001177"
     CDS             8898..9890
                     /locus_tag="ACL8C7_001177"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HGS1395386.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            10108..11151
                     /locus_tag="ACL8C7_001178"
     CDS             10108..11151
                     /locus_tag="ACL8C7_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HGS1395387.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            11197..12900
                     /gene="lpdA"
                     /locus_tag="ACL8C7_001179"
     CDS             11197..12900
                     /gene="lpdA"
                     /locus_tag="ACL8C7_001179"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003001382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HGS1395388.1"
                     /translation="MALEVIMPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKV
                     SMELEAEENGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTS
                     NDDGKSDDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTY
                     LHNAEIIENISHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTV
                     HKGIGTITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMQSPLVMTSDDILEMNE
                     VPESLVIIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGM
                     TILTGTKLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCI
                     KVNEYMETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIY
                     TLPEVAAVGLTEEQAREKYDVSIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGV
                     HIIGPAAAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKK
                     K"
     gene            12964..13953
                     /locus_tag="ACL8C7_001180"
     CDS             12964..13953
                     /locus_tag="ACL8C7_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HGS1395389.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKQLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKIEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(14026..15096)
                     /gene="xerS"
                     /locus_tag="ACL8C7_001181"
     CDS             complement(14026..15096)
                     /gene="xerS"
                     /locus_tag="ACL8C7_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HGS1395390.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(15680..17230)
                     /locus_tag="ACL8C7_001182"
     CDS             complement(15680..17230)
                     /locus_tag="ACL8C7_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HGS1395391.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLVVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLAMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALIGAICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(17246..18025)
                     /locus_tag="ACL8C7_001183"
     CDS             complement(17246..18025)
                     /locus_tag="ACL8C7_001183"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HGS1395392.1"
                     /translation="MATIKEIKEFLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILSKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLKKLGATPIHRTSFEPVKSLVLGKKES"
     gene            complement(18012..18863)
                     /gene="ylqF"
                     /locus_tag="ACL8C7_001184"
     CDS             complement(18012..18863)
                     /gene="ylqF"
                     /locus_tag="ACL8C7_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HGS1395393.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(19082..19258)
                     /locus_tag="ACL8C7_001185"
     CDS             complement(19082..19258)
                     /locus_tag="ACL8C7_001185"
                     /inference="COORDINATES: protein motif:HMM:NF012948.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGS1395394.1"
                     /translation="MQAGIPTDNEVSYDLIYQQETLPATGSSTSELTALGLLAVGSLV
                     LLVHNMTGTVFCSL"
     gene            complement(19310..25096)
                     /locus_tag="ACL8C7_001186"
     CDS             complement(19310..25096)
                     /locus_tag="ACL8C7_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HGS1395395.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPIKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGVPEVQPALSEAVVTDKG
                     EPAVQPELPEAVVSDKGEPEQVAPLPEYKGNIEQVKPETPVEKPKEQGPEKTEEVPVK
                     PTEETPVNPNEGTTEGTSIQGAENPVQPAEESTTNSEKVSPDTSSENTGEVSNKPSDS
                     KPPVEESNQPEKNGTATKPENSGNTTSENGQTEPEPSNGNSTEDVSTKSNTSNSNGNE
                     EIKQENELDPDKKVEDPEKTLELRNVSDLELYSLSNGTYKQHISLEQVPSNPNSYFVK
                     VKSSSFKDVYLPVASISEERKNDKILYKITAKVEKLQQEIESRYKDNFTFYLAKKGTE
                     ETTNFTSFSNLVKAINQNLSGTYHLGASLNANEVELSTDDKSYIKGTFTGQLIGEKDG
                     KHYAIYNLKKPLFESLRGATIEKLSLKNVSISGKDDIGSLANEAQNNTKIKQVHVDGV
                     LAGERGIGGLLAKADQSSITESSFKGRIVNTYETTASYNIGGLVGHLTGSKASLTKSK
                     ATVVISSNTNSSDQTVGGIAGLVDKDAHIQNSYSEGDINNSQRFGKVAGIAGNLWDRE
                     SNSENHAGRLTNVLSDVNVTNGNAISGYHYNGMKITDAFSNKANKVFNVTLEKDEVVS
                     KESFEERGTMLEASQIASKKAEINLLTPPIVEPLSTSGKKDSDFSKIAHYQANRALVY
                     KNIEKLLPFYNKATIVKYGNLVKENSILYQKELLSAVMMKDDQVITDIISNKQTANKL
                     LLHYKDHSSEKFDLRYQDDFANLAEYSIGDSGLLYTPNQFLYDQDSIINQVLPELQQV
                     AYDSEAIRKTLGISPEVKQTELYMEDQFTKTKQDLANSLKKLLSADAGLAGDNPVTRG
                     YLVDKIKNNKEALLLGLTYLERWYNFSYGQVNVKDLVMYHPDFFGKGNTSPLDTLIEL
                     GKSGFNNLLAKNNVDTYAISLASHHGTTDLFSTLENYRKVFLPDKTNNNWFKSQTKAY
                     IVEEKSNIEEVKTKQGLVGTKYSIGVYDRITSATWKYRNMVLPLLTLPEKSVFVISTI
                     SSLGFGAYDRYRNSEHKADKDLNDFVEENARETAKRQRDHYDYWYRILDDNAREKLYR
                     NILLYDAYKFGDDNTVGKATKVASFDDPNPAMKYFFGPVGNKVGHNGHGAYATGDAVY
                     YMGYRMLDKDGAITYTHEMTHNSDQDIYLGGYGRRSGLGPEFFAKGLLQAPDQPSDAT
                     ITINSILKHSKSDSKEGERLQVLDPTTRFKDATDLQKYVHNMFDVVYMLEYLEGQSIV
                     KQLDAYQKMTALRKIENKYVKDPADGNEVYATNVVKELTEAEARNLNSFESLIDHNIL
                     SAREYQSGDYERNGYYTIKLFAPIYSALSSEKGTPGDLMGRRIAYELLAAKGFKDGMV
                     PYISNQYEEDAKQQGQTINLYGKERGLVTDELVLKKVFDGKYKTWAEFKTAMYQERVD
                     QFGNLKQVTFKDPTKRWPSYGTKTINNVDELQKLMDEAVLQDATGTRWSNYNPETDSA
                     VHKLKRAIFKAYLDQTNDFRSSIFENKK"
     gene            complement(25305..26483)
                     /locus_tag="ACL8C7_001187"
     CDS             complement(25305..26483)
                     /locus_tag="ACL8C7_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395396.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDCQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKNGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            complement(26698..30348)
                     /gene="addA"
                     /locus_tag="ACL8C7_001188"
     CDS             complement(26698..30348)
                     /gene="addA"
                     /locus_tag="ACL8C7_001188"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HGS1395397.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMVERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVPISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLN
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEVKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            complement(30345..33620)
                     /gene="rexB"
                     /locus_tag="ACL8C7_001189"
     CDS             complement(30345..33620)
                     /gene="rexB"
                     /locus_tag="ACL8C7_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HGS1395398.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLEYLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRTDLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAEKLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQTTEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            complement(33820..33975)
                     /locus_tag="ACL8C7_001190"
                     /pseudo
     CDS             complement(33820..33975)
                     /locus_tag="ACL8C7_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
BASE COUNT         9833 a         6677 c         6958 g        10653 t
ORIGIN      
        1 cgcaaattac ctacactgat gatgagattc aagtagccaa gttggcaggc aagtacacaa
       61 cagaagacgg ttatatcttt gatcctcgtg atataaccag tgatgagggg gatgcctatg
      121 taactccaca tatgacccat agccactgga ttaaaaaaga tagtttgtct gaagctgaga
      181 gagcggcagc ccaggcttat gctaaagaga aaggtttgac ccctccttcg acagatcatc
      241 aggattcagg aaatactgag gcaaaaggag cagaagctat ctacaaccgc gtgaaagcag
      301 ctaagaaggt gccacttgat cgtatgcctt acaatcttca atatactgta gaagtcaaaa
      361 acggtagttt aatcatacct cattatgacc attaccataa catcaaattt gagtggtttg
      421 acgaaggcct ttatgaggca cctaaggggt atactcttga ggatcttttg gcgactgtca
      481 agtactatgt cgaacatcca aacgaacgtc cgcattcaga taatggtttt ggtaacgcta
      541 gcgaccatgt tcaaagaaac aaaaatggtc aagctgatac caatcaaacg gaaaaaccaa
      601 acgaggagaa acctcagaca gaaaaacctg aggaagaaac ccctcgagaa gagaaaccgc
      661 aaagcgagaa accagagtct ccaaaaccaa cagaggaacc agaagaagaa tcaccagagg
      721 aatcagaaga acctcaggtc gagactgaaa aggttgaaga aaaactgaga gaggctgaag
      781 atttacttgg aaaaatccag gatccaatta tcaagtccaa tgccaaagag actctcacag
      841 gattaaaaaa taatttacta tttggcaccc aggacaacaa tactattatg gcagaagctg
      901 aaaaactatt ggctttatta aaggagagta agtaaaggta gcagcatttt ctaactccta
      961 aaaacaggat aggagaacgg gaaaacgaaa aatgagagca gaatgtgagt tctagttctc
     1021 atttttttca tgaaaatgtg caaaatatag tagattgaaa ctagaatagt atacttctac
     1081 ttctaaaaca ttgttagaaa tcgatttgac tgtcctgttc ttatttcatt ttactatatc
     1141 ttaacagata gtgtaaataa agataaacta tttactggct aattgatcag ttaaacacta
     1201 gttaaggagt aatgatgaaa aaaagaacaa tactattatt gatggccagt ctgttagctc
     1261 ttgtcttagg agcatgtggt ttcttggaca tattgatcct ggatcattct catcaggatt
     1321 actctttact gctattttag aaactggggt ggtttgatgg aaagtattgg tattggtctt
     1381 gttatcgttt cacattccaa acacattgca gaaggtgttg ttgaactgat tagtaaagta
     1441 gctaaagatg ttccgattac ttatgtagga ggaaccgagg gcggaggaat tggaacgagt
     1501 tttgattaag tagatagggt tgtttccgaa aatccagcag atactttact tgcctttttt
     1561 gacctaggtt ctgctaaaat gaacttaaaa atggtgactg atttcagtga taaaagtatc
     1621 atcatcaaca gggttccaat tgtagaaggt gcctataatg cagctgctct tcttcaggct
     1681 ggtgcagaac tgtcagttat tcaaacacag ttagcggagc ttgaaatcaa taaataagga
     1741 attttactat aactcttttt ataggtaagc tattgattat ctcaactata aaatgttaag
     1801 taaatgattt caaaatcaga aagggattgc tttatgcagt tcctttttat tttaacagga
     1861 gtgaaactat agtgtttcta aattgtgaat caatcaaaac tgattgtgat ggggctattc
     1921 tagctttaga aaccttcaaa aattaaaatt taaggcaatc aattacttgg aagaatatga
     1981 aagcatttag tttataggaa ttctaggtct agaattacac atatatttat gaatacgggg
     2041 tgctcgatag ttagtattgt tctattctga aagatttgag ctgtcagttg tatagaaagt
     2101 gttcgaattt tttttaagtg attaaattag ttaattgtat gaggtgcttt atgatataat
     2161 gttcttaatg aattttcaga aaggaaaacc tcaaattgtt ctacaaattt ctactcttcg
     2221 acctcgacca cactcttctt gattttgatg ctgctgagga tgtggctttg acccaacttc
     2281 taaaagaaga aggagttgcg gatattcagg cttataaaga ttattacgtt cctatgaaca
     2341 aggctctctg gaaagacttg gagctgaaga aaatcagtaa acaagagctg gttaacacgc
     2401 gcttttctcg tttattttct cattttggac aggaaaaaga cggtagtttt cttgcccagc
     2461 gttaccaatt ttatctcgct cagcagggac aaacactatc gggcgctcat gatctcttgg
     2521 acagcctcat tgagcgtgat tatgacttgt atgctgcgac aaatggcatt actgccattc
     2581 agacaggacg tttggctcaa tctggtctag taccttattt caatcaagtc tttatctcag
     2641 aacagttgca aactcaaaag ccggatgctc tcttttatga aaagattggc cagcaaattg
     2701 ctggatttag taaagaaaag acgctgatga ttggagattc tctaaccgcc gacattcaag
     2761 gtggcaataa tgcggggatt gacactatct ggtataatcc tcatcacctc gaaaatcaca
     2821 cacaagccca gccgacttac gaagtctatt cttaccaaga cttgctggat tgtttagata
     2881 aaaatattct tgaaaagatc acattttaaa ggagattagc taatgactac aaaaaaagct
     2941 aatattacta ttgaagagta cattgaaatg tctgaagttg attttaataa agctgttaat
     3001 tatgaattta catctgacac ttgtcaatta gcaaatagta tttatcaatc tctttttaag
     3061 ttttttgata agaaaaattt ctctggcgat ttaattttta cttggaaatc tccatcatta
     3121 gtcaaagaag gggattatat tgggagaagg gattcacaag tagataatct tagagtaata
     3181 ggaaatatat ttccgaatta tcttactaat cgaaaatata gcctcaatat gaatcgtaat
     3241 ggctgtatag gagattttcc tcatgacttt tttgatatat acctagatca tgtagcaaaa
     3301 tatgcctacg aacaaaaagt taataatatt aaagagtatt atcctttaaa aagagcgatt
     3361 ttacaccaag agaatgcatt gtattttcga tttttttcta attttgacga ctttttagaa
     3421 aaaaattatt taaagactat atggcaagtt tctaaagaaa ctcctttttc tgaaatggat
     3481 tttaatatgt ttaaaaatat ttcagaaaag ataatcttcg aaagaggtag taaaatgctt
     3541 aatgatttaa aaagtaatta taaaaaatag ccagtcttca taaactgtat tcacgtattc
     3601 aaatcgtata tagtcgatct attaaatctt tagataaact gtaaaaagtg gtttccatag
     3661 ccactttttg ctataataga ggcagtaaaa atgaaggagt cagctatgga acactcgtct
     3721 tggcatgctt tgattaaggc gcaattacct gagggttatt tcgggaaaat caatcagttt
     3781 atggagcagg tctattctca ggggattatt tatccaccca aggaaaaggt ttttcaggct
     3841 ctcttgacaa cactgcttga agaagttaag gtggtaattc tagggcaaga cccctatcac
     3901 ggaccaggtc aagcgcaggg cttgagtttt tctgtacctg actctatccc agctccacca
     3961 tccttgcaaa atatcttgaa agaattgtca gatgatatcg gagttaagaa atctcatgat
     4021 ttgacagctt gggctgagca aggagtcttg cttcttaatg cttgtttgac tgttcctgct
     4081 ggacaggcca atggtcatgc tggtcaaatc tgggagcctt ttactgatgc tgtgattcag
     4141 gtggtcaatc atctagatag accagtcgtt tttgtactct ggggagctta tgcacgtaag
     4201 aagaaggcct tagttaccaa tcctcatcac ttgattatcg aatcagccca tccaagtcct
     4261 ttgtcggttt atagaggatt ttggggttcc aagccctttt ccaaggccaa tgcattctta
     4321 aaagagacag gacaagagcc aatcgattgg cttagataag gagaaaatat gcctcagtta
     4381 gcgacgattt gctacattga taatgggaaa gaactgctca tgctccatcg taataagaaa
     4441 cccaatgatg tccatgaagg gaaatggatt ggtgtgggtg gtaagctaga gagaggagag
     4501 acgccccagg aatgcgcggc gcgtgaaatc cttgaagaaa cagggctcaa agccaagcca
     4561 gttctaaaag gtgtcatcac ttttcctgaa tttacaccag atttagactg gtacacctat
     4621 gtttttaagg tgacggagtt tgagggcgac ttgattgact gcaatgaggg gatgctagaa
     4681 tgggttccct atgatgaggt tttgagcaag ccgacttggg aaggtgacca cacctttgtt
     4741 gagtggcttt tagaggataa acccttcttt tcagccaagt ttgtttatga tggggataaa
     4801 ttgttggata cccaagttga tttctatgaa taaaggagaa agcagatgct actaatcaaa
     4861 aatggtcgtg taatggatcc taagtctggt ttggatcaag tttgtgatgt cttagttcaa
     4921 gatgggaaaa ttatcaaaat tgcgcctgag atcacggaag aaggagcaga aacgattgat
     4981 gctactggtc ttgtggttgc tcctggtttg gtcgatattc atgtgcattt ccgtgaacct
     5041 ggtcaaacac ataaagaaga cattcatact ggtgccctgg cagccgctgc aggtggtttt
     5101 actactgtcg tcatgatggc taataccagt ccaaccattt cagacgtgga gactttgcaa
     5161 gcagttctcc agtcagctgc caaagagaag attaatgtca agacagttgc gaccattact
     5221 aaaaacttta atggtaaaaa cttgactgac tttaaggcgc tcttagaagc tggtgcggtt
     5281 ggtttctctg atgacggtat tccgcttgag agcagtaaga ttgtcaagga agccatggag
     5341 gaagccaaaa aactcaatac ctttatcagc cttcatgagg aagatccagg tttgaacggt
     5401 gttcttggct ttaatgaaaa tattgctaga gaacatttcc atatctgcgg tgctactggg
     5461 gtggctgagt acgctatgat ggcgcgtgat gtcatgattg cctatgcaac taaagcccat
     5521 gttcacatcc agcatttgtc taaggaagaa agtgttaaag tagtggagtt tgctcagggg
     5581 ttaggtgcag aagtcacagc agaagtagcg ccacagcatt tctctaagac agaagcactt
     5641 cttttaacac aaggtagcaa tgctaagatg aatccaccgc ttcgtttgga atcagaccgt
     5701 cgtgccgtta tcgaaggtct caaatcaggt gtcatcacag ttattgcgac tgaccacgcg
     5761 cctcatcatg tagatgaaaa aaatgttgag gatattacca aagcgccatc tggtatgact
     5821 ggcttagaaa catccctgtc tctcggcttg acctatttag tagaagctgg tgagttgagc
     5881 ttgatggaat tacttgaaaa aatgacatac aacccagcca agctttacaa ctttgaagca
     5941 ggttacttgg ctgagaatgg tccagcagat atcactattt ttgatgccaa ggctgaccgc
     6001 cttgtggact cccattttgc ttccaaagca gctaattcac cattcatcgg tgaaacctta
     6061 aaagggcagg ttaaatatac catctgtaag ggacaaatcg tctatcaagc ttgataggag
     6121 ttagaatatg aattattttc gaaaacgtag ggagagacaa gcgaaatcta atagtggaat
     6181 ttactgtccc gcagctaatc gttccaaaat tcaatatgaa actaaagaaa aagctgacca
     6241 tgcggttcaa tatgataacg gaggtttagt tagaagctat tattgtcgta catgtgcgtg
     6301 ttggcatact acttcaaaat ctaataaacc tccgctaagt ttgaaaaact atggtctgaa
     6361 actctttggt ttagataaat cagaatagaa agagaagtat gtataagaca aagtgtttac
     6421 gagagaagtt agtattattt ttaaaaattt tcttcccaat cctgatctac caatttgcca
     6481 attattctgc ctcttttgtt gatactgcaa tgacaggtca atacaacact atggacttgg
     6541 ctggtgtatc tatggcaacc agtatctgga atcctttctt tacatttcta acagggattg
     6601 tgtcagcctt ggtgcctatc attggtcacc atcttggtcg aggcaaaaag gaagaagttg
     6661 cgtctgattt ttaccaattt atttatttgg ccttgggcct atctgtggtc ttgctgggga
     6721 tggtactttt cttggcacca acaatcttga atcatattgg gttagaagca gcagtagcgg
     6781 cagtagcggt tcgctatctt tggtttttat ctatcgggat tatccccttg ttgctcttta
     6841 gcgtcattcg ttccttgctg gattcgctgg gcttgaccaa actgtccatg tacctcatgc
     6901 ttttgttact ccctctcaat agcggattta actatctctt gatttacggt gcctttggta
     6961 ttccagaact gggaggggct ggtgctggtt taggaacatc cttggcctac tgggtcttgc
     7021 ttgggatttc tgttctggtt ttatttaaac aggagaagct caaagcctta caccttgaga
     7081 aacgaattcc acttaatatg gataacatta aggaaggagt tcgtttaggt ctgcctattg
     7141 ggggaactgt cttcgcggaa gtggctatct tttcagtggt tggcttgatt atggctaagt
     7201 tttcgtcctt gattatagct agtcaccagt cagctatgaa cttttcaagt cttatgtacg
     7261 cctttcctat gagtatctca tcggctatgg ctattgtcgt ttcctatgaa gtgggagcca
     7321 agcgatttga tgatgcgaaa acctatattg gtctaggaag atggactgcc ctcatttttg
     7381 cggccttcac cttaaccttc ctttacattt ttaggggaaa tgtggccagt ctttatggta
     7441 acgacccaaa atttatcgat ttgacagtgc gttttttaac ttatagtctt ttcttccagt
     7501 tagcagatac ctttgcggcg ccgcttcagg gaattttgcg ggggtataag gatacagtta
     7561 ttccttttta ccttggtttg cttggttatt ggggcgtagc aatccctgtg gctacgctat
     7621 ttgattccct aacagatttt ggagcttatt cttactggat cggcttgatt attagtttga
     7681 ttgtgagcgg ggcgctctac cgttggcgtt taactgtgat tatgaagaga tttgaatctt
     7741 tagcaaaatc caaatgctaa aaagtttgtg aaaaaatatt cttgacaaga aaatcccttg
     7801 ttttcacggg gttttctttt ttattttgtg aaatttcttt tagaaaaact ttgacagtat
     7861 ttgccaaaag cggtaaaata gtaaggtaag aagaaagtta gaaaggcaag aagatgtcaa
     7921 ctttagataa aaatcttttg ctagaaatgt tccgtaagat ggaagaaatc cgtcgcatgg
     7981 acttaaaaat tgcacaatta gtaaagaaag ggaaagtgcc aggaatgacg cacttttctg
     8041 ttggtgaaga ggcagctaac gtgggggcta tgttagctct caatccagat gatctgatta
     8101 cctcaaacca ccgtggacac gggcaagcta ttgctaaagg gattgacctc aacggaatga
     8161 tggctgaaat ccttggtaaa tacactggaa cctgtaaagg gaaaggtgga tctatgcata
     8221 tcgctgacct tgatgctggg aaccttggtg ccaatggtat cgtaggtggt ggtatgggga
     8281 tcgctgtcgg tgcagccctc agtcagcaaa tgcaaaatac cggtaaaatc gttgtctgct
     8341 tctttggaga tggtgcgacc aatgaaggtg ttttccacga agcagtgaac atggcttcta
     8401 tctggaacct gccagtcatt ttctattgca ttaacaacgg ttacggtatc tctgcggata
     8461 tcaagaaaat gaccaatata gaacatatcc atcaacgtag cgccgcttat ggaattcctg
     8521 gaatgttcat cgaagacggt aacaatgtca tcgatgtcta tgaaggattt cagaaagctg
     8581 tagaccatgt tcgcagtggc aatggtccag tcttgattga aagtgtaact tatcgctggc
     8641 tcggtcactc atcatctgac cctggtaaat atcgtacgcg tgaagaagtg gaattgtgga
     8701 aacaaaaaga tccaatcgaa aacctccgca attaccttat tgaaaataac attgcaagtg
     8761 ccgaagaatt ggaagaaatc caagcgcaag taaaggaagc agtagaagct tctgttaaat
     8821 ttgcagagga aagcccattc ccaccgcttg aatcagcctt tgaagatatt tacgcagact
     8881 aaggaaaaag agataaaatg gaaacaaaaa caatgtcctt ccgtgacacc attatccttg
     8941 ctatgtctga ggaaatgcgt cgcgatgaaa atgtgttctt gatgggagaa gacgtcggtg
     9001 tcttcggagg agacttcggt acttctgttg gaatgcttga agaatttggt ccagaacgtg
     9061 tccgtgactg tccgatttct gaagctgcca tctctggagc agcagcagga gcagccatga
     9121 caggacttcg tccaatcgtc gatatgacct tcatggactt ctctgttatt gccatggaca
     9181 atatcgtcaa ccaagctgct aaaacacgtt acatgtttgg tggtaaaggt caggttccaa
     9241 tgactgttcg ttgtgcagct ggtaacggag ttggctctgc cgcccagcac tcacaatctc
     9301 tagagtcttg gtttactcac attccaggac ttaaggttgt ggcacctgga acacctgcgg
     9361 acatgaaagg cctgcttaag tcttctatcc gtgataacaa cccagttatt atacttgagt
     9421 acaagtcaga atttaaccaa aaaggggaag tgccagttga tccagactac acaattccac
     9481 ttggggttgg tgaaatcaaa cgccaaggaa cggatgtaac agttgttact tatggaaaaa
     9541 tgcttcgccg tgtggttcaa gctgctgaag aattagcaga agaaggaatt tcagttgaaa
     9601 ttgttgaccc acgtaccctt gttccgcttg ataaggatat catcataaac tcagtgaaga
     9661 agactggtaa ggttgttctg gtcaacgatg cccacaaaac aagtggctat atcggtgaaa
     9721 tttcagctat tatttcagaa tcagaagcat ttgactatct agatgcacca attcgccgtt
     9781 gtgcaggaga agatgtgccg atgccttatg cacaaaacct agaaaatgca atgattccaa
     9841 cagttgaaag tatcaaagat gcaatccgaa aaacttataa caaagaatag agttacataa
     9901 gataagttat gtaaataaaa taaagctgac gagaaacttt gtatctttta ggtgcagagc
     9961 tcttcgtcat taatatctta gattagagca cgggctaaaa gctcggaaaa aagataaatc
    10021 tccttggctt catcgaagcc atcgtcgatt tcctattttt cagtcgcttt tgacgccctt
    10081 tgtatcataa atagaattgg agaggtcatg gctgatgaca agctaagagc gactcctgca
    10141 gctagaaagt tagcggatga tttagggata aacctctacg acgtttctgg ctcaggtgca
    10201 aacggtcgtg tccacaaaga agacgtggaa acttataaag acacaaacgt ggttcgcatt
    10261 tcgccacttg caaaacgaat tgccctcgaa cataacattg cttggcagga aatccaagga
    10321 accggtcatc gtggtaaaat catgaagaag gatgttttgg ccctgcttcc tgaaaatatc
    10381 gaaaacgata gcatcaaatc tcctgctcag attgaaaaag tggaagaagt ccctgataac
    10441 gtaacaccat atggtgaaat cgagcgtatt ccaatgacac caatgcgtaa ggttattgcc
    10501 caacgcatgg ttgaatctta cttgactgcg ccaaccttca ccctcaacta tgaagttgat
    10561 atgactgaaa tgttggctct tcgtaagaag gttcttgagc caatcatgga agcaactggg
    10621 aagaagacta ctgtaacaga ccttctttcg cttgcagttg ttaagactct tatgaaacac
    10681 ccatacatca atgcttcatt gacagaagat ggcaagacta ttatcactca caactatgtc
    10741 aatcttgcca tggcagttgg gatggataat ggattgatga cacctgttgt ttacaatgct
    10801 gagaagatga gtctttcaga actggttgta gcctttaagg atgttattgg ccgtaccttg
    10861 gatggtaaat tggctccaag tgagttacaa aattcaacat tcacaatcag taatttggga
    10921 atgtttggtg ttcagtcctt tggcccgatt attaaccaac ccaactcagc tatccttggt
    10981 gtcagttcga caatcgagaa gccagttgtc gtcaatggtg aaattgtgat tcgcccaatc
    11041 atgagtttag gattaaccat tgaccaccgt gtcgtagatg gtatggctgg tgctaagttt
    11101 atgaaggact tgaaagagtt gattgaaacg ccaatctcaa tgttaattta agagcaagag
    11161 tattcatttt taagatatag ataaaggaag gaagacatgg ccttagaagt aattatgcca
    11221 aaagccggcg tggatatgac agaaggacaa atcgtccaat ggaataaaaa agtcggagaa
    11281 tttgtaaaag aaggagaaat ccttttggaa atcatgactg ataaagtcag catggaattg
    11341 gaagccgaag aaaatgggta cttgattgcc attctcaaag gagatggtga aactgtccct
    11401 gtaacggaag ttatcggtta ccttggtgaa gaaagggaaa acatcccaac agctggagca
    11461 gcatcgccag aagctagccc tgtacctgta gcaagtacct caaacgatga tggtaagagc
    11521 gatgatgctt ttgatatcgt tgtgattggt ggaggtcctg ctggttatgt tgcagccatt
    11581 aaagctgccc aactcggcgg taaggttgcc cttgttgaga aatctgaact tggtggaacc
    11641 tgcttaaacc gtggatgtat tccaaccaag acctaccttc ataacgctga aattattgaa
    11701 aatatcagtc atgctgcaaa tcgtggtatc gtgattgaaa atcctaactt cactgttgat
    11761 atggaaaaac ttttagaaac taaatctaaa gttgttaata ctcttgttgg tggtgttgca
    11821 ggtcttcttc gtagctacgg agttactgtt cataaaggaa ttggtacaat cactaaagac
    11881 aagaacgtct tggtaaatgg ttctgaattg cttgaaacca agaaaatcat tcttgctggt
    11941 ggttcaaaag tcagcaagat caacgtccct ggtatgcaat ctccacttgt catgactagt
    12001 gatgacattc ttgaaatgaa cgaagtgcca gaaagccttg ttatcatcgg tggtggagtt
    12061 gtcggtatcg aactcggtca ggccttcatg acatttggtt caaaagtgac tgttatcgaa
    12121 atgatggacc gtatagttcc agctatggat gcggaagttt ctaagaacct tcgcttgatc
    12181 cttgagcgta aaggaatgac catcttgact ggtactaaac tgcaagaaat cattgaggaa
    12241 aatggtcaac ttcgtatcaa ggttgaagga aaagacgata tcatcgcaag caaagctctt
    12301 ctttcaattg gtcgtatgcc agaccttgaa ggtattggag aggttgagtt tgaattggat
    12361 cgtggttgta tcaaggtcaa cgaatacatg gaaacttcag ttccaggcat ttatgcacca
    12421 ggtgacatca acggtactaa gatgttggct cacgcagctt tccgcatggg tgaagtttcc
    12481 gctgaaaatg cccttaaagg aaatcatgca gttgccaaat tgaatttgac tcctgcagcc
    12541 atctacactc tccctgaagt agcagcagta ggtttgacag aagaacaagc ccgtgagaaa
    12601 tacgatgttt ccatcggtaa gtttaacttt gctgctaacg gtcgtgctat tgcatctgac
    12661 gcagctcaag gtttcgtaaa agttatcgct gataagaaat acggagaaat ccttggtgta
    12721 cacattattg gtcctgcagc cgcagaatta ataaacgaag catcaagcat catcgaaatg
    12781 gaaattactg ttgaggaaat gctgaagacc atccacgggc acccaactta ctctgaagtg
    12841 atgtacgaag cgtttgcaga tgttctagga atggccatcc attcacctaa gaaaaaataa
    12901 aacgaagata gattagactg gaaggttatt tccagtttct atcatataaa gtaaagggat
    12961 atcatgaaat acattatcaa tcattcaaat gacactgctt ttaatattgc cttggaagaa
    13021 tacgccttta aacaactttt ggatgaggat caaatcttcc tactttggat taacaagcca
    13081 tctatcattg ttggtcgtca ccagaacact atcgaagaaa tcaaccgtga ttatgttcgc
    13141 gaaaatggta ttgaggtagt tcgccgtatt agtggtggtg gagctgttta ccacgattta
    13201 aataacctca actacacgat catctccaaa gaagatgaaa ataaggcatt tgacttcaag
    13261 agcttctcaa ctccggttat caataccctg gctcaacttg gggttaaagc tgagttcaca
    13321 ggtcgtaatg accttgagat tgatggtaag aagttctgtg gcaatgccca agcctatatc
    13381 aacggccgta tcatgcacca cggttgcttg ctctttgacg ttgatttgtc agtcctcgca
    13441 aatgccctta aggtttcaaa agataaattt gaatcaaaag gtgtgaaatc cgtccgtgcc
    13501 cgtgtaacca atattatcaa tgaattacca aaaaaaatca cagtcgaaaa attccgtgat
    13561 ttactcttgg aatacatgaa aaaagagtac ccagagatga ctgaatacgt cttttcagaa
    13621 gaagaattgg ccgaaatcaa tcacatcaag gatactaagt ttggaacttg ggactggaac
    13681 tatggtaaat cacctgaatt taacgtccgt cgtggaacca aattcactag tggtaagatt
    13741 gaagtctttg ctaacgttac tgaatcaaaa atccaagaca tcaagattta tggtgacttc
    13801 tttggtattg aagacgttgc tgcagtagaa gatgtccttc gtggggtgaa atacgaacgc
    13861 gaagatgttc ttaaggcgct aaaaaccatt gatatcacac gctacttcgc tggtattagc
    13921 cgtgaagaaa tcgctgaagc ggtagttgga taaatcaaaa agaagttggc caactaacca
    13981 acttcttttt ttgatattta tttacataat ttaaaatacg taaaatcata aactatccag
    14041 agcattcttt tgttcatcat taacaatatg ggtatagagg tcagtgactt gtgtgctggc
    14101 atgtcctagt tggtgactga ctaaaacttg tgatttagta gcatcataga gcctagttgc
    14161 tagtgtatgg cgcagtttat ggggtgttac acgtacttta aaatcctctg agtatttagc
    14221 aaccattttc tcaacgctag aagcatcgat acgattagga acacctctgt agagagttaa
    14281 aaaaagggct gtatctgttt tttccgtttt atagcgttga ttccgaatgg ccagataatt
    14341 ctctaaataa ggtttagcaa aagcagcgac attgactgag tcacgtttgc caccttttcg
    14401 agtaacatca ataaccatca tttttagatt gagatctctt agatctagat taacagcttc
    14461 agataagcga acaccagatg ccaagagaag ggcaataatg gctaaatctc gttctttatt
    14521 tttgttgaat gatgagagag ctcgatttga aagctgttgt gggtgctctt gatcgatata
    14581 agttagaaaa ccttctgttt catcacctag aaagagtttt tgcttgatat tttcagctct
    14641 ggcagcaagg gtttctttct ttttcttggt tgaaactttt ttcattacat tacgatagaa
    14701 ataaggttcc ccctgatcgt tttcaacctc ctcggttaga tacttgtaaa gactagaaag
    14761 tgctgataag gttcgattga tagttgtctg tgaaacacct tgttttgttg tattagcatt
    14821 cagcaaggga cgttcacgta gataaaggat aaaggattcc atgtctttct tagacatatt
    14881 ttccaaaact gataaaggaa tatcggatat tttatcagcg tttgaaatac cagactccaa
    14941 aacccagctg aaaaatcggt catattcctt aaggtattcg tacagggttg taaaactgta
    15001 gggcacagcc agtttagatt ggtagtattc cagaacatac cagggcatga gttgttttag
    15061 tttgtcgatt cgttccagta aaatctcacg tttcatgtat tttctccata attaagtata
    15121 ctagtagtat agcatagact tgtatatttt tcaagaaaat tatagttttt cagaaagatg
    15181 ttataggagt ttttcaaagt gataaaaaga cttagaccta caaacaaaac agaataagga
    15241 aaataatgaa aatctcaccc actaaacttc tgttaatact acataactga agagctatat
    15301 aaggagctat gagatacaaa acacattgta taatagattg aaactagaat agtacatctg
    15361 gacttctaaa acattgctag aaattgattt gattgtcctg attgttttat cctatttcta
    15421 tttcatttca ctatataatt gctattgttt tctttttcat gattttaatc ttactgtaca
    15481 gatttgatac agtaaactcc tttctagctt tatgctttat catttctaac ttaattatag
    15541 tcttattttt aataaagttc aattatttat atgtaaaatt cctcattagt aaaaaataac
    15601 cgatctcatt tctgagaatc ggttttctaa ataaatcaaa ctgatcattt acataacata
    15661 aattatgtaa atgattatac tacaacaaca aatctttgac ttttccaatt tcactttttg
    15721 gaataaccag gtgaatcata tcacccagat acattctggt tgagccgtta actgtttggc
    15781 tcttgccatt atggacttga gttgtgatga ggacgttgtg tggtaagttg agttcatgaa
    15841 cttgtttccc agcaatttta tcagaaactg gtatttcgat aagtgtaact tctccttcgc
    15901 tagatacttc ttctggaagc attttttcca gcatggcttc atagactggc gtacctttga
    15961 gcaaatccat gataatataa gaaacaagag tgacaagacc aagtggcata aggttgcgaa
    16021 tatctcctac catctcagtt acgaggatca tagcggttaa gggagctttt gatatggctc
    16081 caaaatagcc actcattcct agaatgacaa atatagggaa ttgctcttga ctgacaagtc
    16141 caagattgac acagatagca ccaattaagg caccaagcaa agaaccaaga gctaaaatgg
    16201 ggaggaaaat tcctcctggc agtccacttc catagctaat catactccaa ataaagcgga
    16261 tcaaaaagta agctaataaa acttggaaac taaaattttg ttcagttaaa gaaaggacaa
    16321 gctgatttcc gccaccaatg atttgaggta agaagattcc gactggtatg ataaggataa
    16381 aagccaagat gggataataa gctctatcca aatggatttt ttgaccaatc aagtcataaa
    16441 ctcttccaac gtttaataca gctttctcat agagaaagcc tgaaaatcca aggaaaattc
    16501 ccatggcgag atatatccaa tactgatcta gggtcatggg aggaatgtta tctggcatat
    16561 ccaatactgg tgtcaaaccg aacatgagta gagacacaaa gtttgctacg atgctggctg
    16621 ctagagttga gacccagaaa aagcgcgaaa aatggtgata gacttcttct acaacaaaga
    16681 gaagtgctgc aataggagca ttaaaggctg cggctaaacc tgctgcagct ccactggcaa
    16741 tcaaggaacg ttcctctact ggactagatt tgagccactt agcaattcct ttaccaccaa
    16801 ctgctccaag ttgaatactg ggtccctctc gacccaacat gagtccactg gcaatagcaa
    16861 gaatacctag cacatatttt ttccaaagaa tgccccacca gttgagggac atgaggcctt
    16921 tcagttcggc ttcgacttga ggaattcctg agcctttaat atctttttct gaccgtgtta
    16981 gtttggcact gagccaacag atgagtatat aaaacaaaac cagtacaaaa agattgcgca
    17041 ctaagtaccc ttgatcttga taaactcctt gtatcaggtg gaagcccttt tcaattaaga
    17101 aacgaaagga tccgacgata attccaacga cgaggccgac aatgattcct cgaccaactt
    17161 gggatagtat agtgctggat gcaaaggcga attctttctt agaacggact atttccgact
    17221 gttcctccat ggtatttcct ttcaattaac tttctttttt acctaaaacc agtgatttaa
    17281 cgggttcaaa gctggttcgg tgaattgggg tagctcctag ttttttgagg ccttccagat
    17341 gtttagctgt gccatatcct gcattagtag cgaaatcata gccagggaac tgctgatcgt
    17401 attctttcat caattcatca cgtgttacct tggctactat agatgctgct gcgatagaga
    17461 gggagttggc atctcctttg ataatggagg tttgtgaaat gggcaagtcc agtttcatgg
    17521 catcaatcaa aaggtgctct ggttgagggc tgagctggga gattgcttct tgcatggcta
    17581 gtttggttgc ttcatagatg ttgacttggt cgatgacctg attatctatg ataccaattc
    17641 caatcgacaa ggcttggtct tgaacggctt ggaaaatctc cagatgtttc tttttaggaa
    17701 ttttcttgct gtcgttgaga cctttaatct tacaattttt agataaaata acggccgcag
    17761 cgactacagg accagcaaga ggaccacgac caacctcatc aatacctgca attaaggtca
    17821 atccttgctt ataaagttct ttttcataag aaagcatgga ttccaagcgc aaattttcat
    17881 ctaattcagc ttgaatggct cttttacgct tgctgatttc cttttgaact cctgagcgat
    17941 tatccttttc aagctctaaa aaaatagggc tttctaactc cttgactgtc acaaggaatt
    18001 ctttgatttc tttaatcgtt gccatcgagg tcttccaatg tatctaaggt atagttaccg
    18061 agtttgccat cacggacttc cttcacgaag agactgtaaa aacggtcata gtcatcacgg
    18121 aaaccgaggg cgcgggtcat atccataata atcacaggcg cttcttcttc aattttcatt
    18181 tgtttgaagc gttcagccag cttttctgga taatgttctt tgaaataatt gataccaaaa
    18241 atggtaacct catccatagg aagcaactgg tctttgatag ctccagtcaa tgccaactta
    18301 agtgcaacag tttcatcctc aaacttaggc cagagaatcc ccggtgtatc caagatttcc
    18361 aggtctttat tggttttaag ccattgttga ccttttgtga cccctggctt gtttccaaca
    18421 acagcaatct ttttaccagc caaacggttc atcagagttg atttaccagc gtttggaatc
    18481 ccgataatca tagtacgcaa ggtttcaatc tgaatcccac gttctttctg gcgagcaatc
    18541 ttatcagcca tgagcttctt ggccgcatct gttacaactt ttacagtcac ttgctctttg
    18601 gagttgatag ctagcgtctg gattccttgt gattcaaaat actgacgcca ttccttggtc
    18661 attgctggat cagccaagtc ggccttgttt aaaatcaaga gttttggttt atcaccaaca
    18721 atcttggtca acataggatt ttgactagat agaggcaagc gtgcatctac taaaatcgtc
    18781 acaaaatcaa caaattttaa attctcctgc acctgtcgac gagctttaga catgtgacca
    18841 ggaaaccatt gaatagtagc cattgagttt tttcctttca tagcaaggat ttagatcccc
    18901 tattttattt tactattgtt tgaacataga gagttttcaa atgaatgatg tccaaacagt
    18961 tcttgtttta tgacatagaa atctacttta tattatatca tgccttcttt attttgtccg
    19021 atgatagcct tttaccctat cttttaccct atatagaaaa aagccatcaa atgatgactt
    19081 ttcagaggga gcaaaaaact gttcccgtca tattatgaac caaaagaact aaactaccaa
    19141 cagctaatag gcctaaagct gtaagctcag aagttgatga acctgttgca ggaagagttt
    19201 cctgctgata aataagatca taacttactt cattatcagt aggaattcct gcttgaatct
    19261 tggtttgttc ttcatcacct ttttaaactt tatttcctaa tagtaaacac tattttttat
    19321 tctcaaaaat tgaacttcta aaatcatttg tttggtcaag ataggcttta aagattgctc
    19381 tcttcaactt atggacggca ctgtccgttt ctggattata attactccaa cgtgtacctg
    19441 tagcatcctg caaaacagct tcatccatta gtttctgcaa ttcatccaca ttattgatag
    19501 tctttgtgcc atagcttggc catcgttttg tcggatcttt aaaggtcacc tgcttcaagt
    19561 ttccaaactg atccacccgt tcttggtaca tagctgtctt aaattctgcc caagttttat
    19621 acttaccatc aaataccttt ttcaaaacaa gctcatcggt caccaagccc cgttctttac
    19681 cataaagatt gatagtttgc ccttgttgtt tagcatcttc ttcgtattgg ttggaaatat
    19741 atggtaccat accatcctta aagcctttgg cagccaaaag ttcgtacgca atcctacgtc
    19801 ccataaggtc ccctggtgtg cctttctcac tgctgagagc tgaatagatt ggggcaaaga
    19861 gtttgatggt atagtagcca tttcgttcat agtcgccaga ctggtactca cgagctgata
    19921 agatgttatg gtcaatcaaa ctttcaaaac tattcaggtt tcgggcctct gcttctgtca
    19981 attctttgac tacgttagtg gcataaacct catttccatc tgcaggatct ttcacgtatt
    20041 tattctcaat ttttctcagg gccgtcattt tctgataagc atctaactgt ttcacgatag
    20101 attgcccttc gagatattcc aacatgtaaa cgacatcaaa catattgtgg acgtattttt
    20161 gaagatctgt tgcgtcttta aatctcgtag ttggatcaag tacttgtaat cgttctcctt
    20221 ctttactatc agattttgaa tgtttcaata tagaattgat agtaatcgtt gcatcacttg
    20281 gttggtctgg tgcttgtagt aagcctttag caaagaactc aggtccaagt ccacttcttc
    20341 ttccataacc accaagataa atatcttgat ctgaattatg cgtcatctca tgagtatacg
    20401 taatagctcc atccttatct agcatgcgat accccatata atatactgca tcccctgtag
    20461 cataagcacc atgtccatta tgaccaactt tatttccaac aggaccgaag aaatatttca
    20521 tcgcaggatt tggatcatca aaacttgcta cttttgtagc tttccctacg gtattatcat
    20581 cgccaaattt ataagcatcg taaagcaaaa tatttctata aagtttttca cgtgcattgt
    20641 cgtctaaaat acgataccaa taatcgtagt gatctcgctg acgtttggct gtttcacgtg
    20701 cattttcttc aacaaaatca ttgaggtcct tgtctgcttt gtgctcacta ttgcggtaac
    20761 gatcataagc tccaaatcct agactagaga tggtcgagat gacaaagact gatttctccg
    20821 gcaaggttag gagcggcaag accatattgc ggtatttcca tgtggcacta gtgatacggt
    20881 catagacacc aatagaatac ttagtgccaa ctagtccttg cttcgttttc acctcttcga
    20941 tattggattt ttcttcgaca atgtaagcct tagtctgtga tttaaaccag ttattattgg
    21001 ttttgtctgg tagaaagact tttcggtaat tttccaacgt gctaaacaaa tctgtcgttc
    21061 catgatggct ggcaaggctg atagcataag tatcgacatt gtttttagca agaagattgt
    21121 taaagccaga tttacctaac tcaatcagag tatctaatgg tgaagtattt cctttaccaa
    21181 agaagtccgg atgatacata actaggtctt tgacattcac ctgaccatag ctaaagttat
    21241 accaacgttc taaataagtt aaaccgagta gtaaggcttc cttattgttc ttgattttat
    21301 ctacaagata gcctctggta actgggttgt caccagcaag tccagcatct gcagacaaga
    21361 gttttttcaa actgtttgcc aaatcttgct ttgttttggt aaactggtct tccatataga
    21421 gctcagtttg cttgacctct ggagaaattc cgagtgtctt tctgatagct tctgaatcgt
    21481 aggcaacctg ctgtaattca ggtaaaactt gattgatgat agagtcttgg tcatacaaga
    21541 attgatttgg cgtatagaga agcccactat ctccaatgct atattctgcc aaattggcaa
    21601 aatcatcctg gtacctgaga tcaaactttt cagatgaatg gtccttgtag tgaagcaaga
    21661 gtttgtttgc agtctgtttg ttggaaataa tatctgtgat tacttggtca tccttcatca
    21721 taactgcaga caagagttct ttttgatata agatactgtt ctccttaacc aggtttccgt
    21781 atttcacgat ggtcgccttg ttatagaaag gtaacaattt ttcaatgttc ttataaacca
    21841 aagcacggtt ggcttgataa tgggctatct tagaaaaatc actgtctttc ttaccgcttg
    21901 ttgagagggg ttccactatt ggtggagtga gaagattgat ttctgctttt ttgcttgcaa
    21961 tttgagaagc ctctagcatt gttcctcttt cctcaaagga ttctttgcta acgacctcat
    22021 ccttctctaa agtgacattg aaaactttat tcgctttatt actaaatgca tcagtaattt
    22081 tcattccatt ataatggtaa ccactaatgg catttccatt agttacattg acatcactaa
    22141 gcacattagt caatcttcca gcatgatttt cactatttga ttcacgatcc cataagttac
    22201 ctgctatacc agcaactttt ccaaaacgtt ggctattatt aatatcccct tcagaatagc
    22261 tattctgaat atgcgcatct ttgtctacaa gaccagcgat acctccaacg gtctggtcag
    22321 aactatttgt atttgatgaa atgaccactg tcgcttttga cttagtcagt gaagctttgc
    22381 ttcctgtcaa atgaccgacc aggccaccga tattatagga agcagttgtt tcataggtat
    22441 tgacaattct tcccttgaaa ctactctctg tgatgcttga ttgatctgcc ttagccaaca
    22501 aaccaccgat accacgttca ccggcaagta caccatccac atgaacttgc ttaatttttg
    22561 tgttattctg agcttcattt gccagtgaac cgatatcatc tttccctgaa atagagacat
    22621 ttttcagact caacttttct attgtggccc ctctcaagct ttcaaaaaga ggctttttca
    22681 agttgtaaat agcataatgc ttaccatctt tttcaccaat caactgacca gtaaaggttc
    22741 ccttgatata ggatttatca tcagtgctaa gctccacttc gttagcattc aggctagctc
    22801 ctaaatgata ggttccagag agattttggt ttatagcttt gaccagatta ctaaaggaag
    22861 taaagtttgt tgtttcttct gttcccttct tagctagata gaaggtaaaa ttatctttat
    22921 atctgctttc tatctcctgc tgaagcttct ctacttttgc tgtgatttta taaaggattt
    22981 tatcattttt tctttcctct gatattgatg ctactggtag gtatacatct ttgaatgaag
    23041 aagatttcac tttaacaaag tagctatttg gattgcttgg aacttgttct aacgaaatgt
    23101 gttgtttata agtaccattt gacaaactgt ataactctag gtcggaaaca tttcttaatt
    23161 caagtgtttt ctctggatct tctacctttt tatcggggtc tagttcattt tcttgtttaa
    23221 tttcttcgtt tccatttgaa ttggatgtgt ttgatttggt tgaaacatcc tcagttgaat
    23281 ttccgtttga tggttctggt tctgtttgtc cattctctga tgttgtatta cctgaatttt
    23341 ctggttttgt tgcagttccg tttttttctg gttgatttga ttcttcaact ggtggttttg
    23401 aatcactagg tttattggat acttccccag tattttcgct agatgtatct ggtgatactt
    23461 tctctgaatt cgttgttgat tcttctgcag gttgaactgg attttctgct ccttgaattg
    23521 aggttccttc tgtagtacct tcatttggat ttactggtgt ttcttctgtt ggttttactg
    23581 gaacttcttc agttttttct ggaccttgtt ctttcggctt ctcaaccgga gtttcaggtt
    23641 ttacttgctc aatattcccc ttatattctg gcaatggggc tacctgctct ggttcacctt
    23701 tatcacttac aactgcttcc ggtagctctg gttggacagc gggctcacct ttgtcggtta
    23761 cgactgcttc cgataacgct ggttgaactt ctggtacgcc tttatcactt actactgctt
    23821 cgggcaactc aggctgaatt gcgggttcaa caatagctcc agactgtacg tccttatgtt
    23881 ctacaccagt ctcaggttgt tcctttataa cttgagtttt tttagtacct ttttcgacta
    23941 ttcttggact aggcgcagtc gttgaagttg aaacaatttc tcgcgaaact tcttccttgt
    24001 ttacagagaa tattctgacg atttcaactt tcttacctaa tttaccttct tgttttactc
    24061 ttacagttcc ttcagctaaa tcaggatttt cttgaatttc ttcttgaaaa tctatttttg
    24121 tctctatagt ttcctcacga tataagagtt caggtttgtt caattgacct gataaaactt
    24181 catcctgtgg atttaatgta tttaccccag tcttttcttt tggagaaatc ttctcctctt
    24241 tcttcgtttc tagattctta tgttcggcta attgttcttg agaatctgaa gattgtttct
    24301 cttcttttct tggattgatt aattcagtag agaaaggttt ttcaactact tgaacttctg
    24361 tcggcttagt tgaagaaaca ggtgtttgtt cctgaatagc ttgtactgtt gatggatggt
    24421 ctacaaaatt tggtgtaaca ttataatcca ccttttgttg ttttatagga gtggctgctg
    24481 atttttcttg attacttact tcaaaatcag aagtcgtttt tccctctttg atatatccaa
    24541 tataagtgta acctgaaatc tctttaggaa gaggtaattt ttctccagag gtcaattcat
    24601 agtccgtatt gtaatttagc aaaagatgat tttctaaagc atggactgaa actaagacac
    24661 catttcctat tcccgcaacc aatactaaat gtaataccgt tttattctta acctttttct
    24721 tggaaacagc aaaaattaaa attcccagag cagctaagct agcaccagca actagggctt
    24781 gcctctcatt cttgcttcca gtatttggta attccgccag ttgattttga gaatttaact
    24841 tataaacaag ataataagtt tcatcatcat tctccacgta tgtcggaata tcatagacaa
    24901 gctgcttctt ttcttctgat gatagctctg aatctgccac atatttatag tgaactcccg
    24961 cagtttcttg agcatccaca gatgaactag ctaatacaga cataaaaaat aaacttgaaa
    25021 tcgttgcaga tacaagtcct actgataatt ttctaaatga aaaacgctct tgtttttcac
    25081 caaaatactt ttccattatt cctccttgaa ataaaattta tatatgttac aaagaccttt
    25141 attatattag tgtattatct attatctata gaaaaggcag tataccttaa ttatactctt
    25201 aatttacaaa aaagtcttaa aattgagatg cgctttcata ctttgtttta tattattttg
    25261 aggtacaata acacctacca tgaaatttac acggtaggtg ttactcatat cactaatcgt
    25321 tctaaaaatg gtttgaggca gttgaggaga attccttcta tccagcttcc ttgtgctgat
    25381 gagcgatggt cttcctgcag gctttttttt agaaaatctc ggacttgttc tggtgcgatt
    25441 tcaaattcaa aggctttcat tttatagaaa aagtcgatga gatgatctga caggtattca
    25501 gttgaaaagg gtacttcacc attttttcga tattctaata agagcctaga aaatcgagct
    25561 ttttcttcag gaagctcacg aaaataggaa ttgaggagcc aagtctgctt ctgttttctt
    25621 tcaattggat cctgactggc aattcgttgg tctttttcca gctctttttg gtattgtttg
    25681 gccttgatag cccgttctgc tctattttta ccaaaaagaa ttttttccca cttgcgttct
    25741 tcttgagtca gggtctctgt aaagccaaag taatcttgat aagcacgctc tgcgggtccc
    25801 atggctagaa ccagattgtc tgcatattgc ttggcgattt tatccctctt cttgcgttct
    25861 ttctctgcct ggatacggag ttcttgttcg tagtcaattt tctccttgcc tagcttgaca
    25921 aggtagagtt ggtcatccga tttcccaagt aaaaagggtt tgatacactt ttcaaggact
    25981 tcttccatcc gagccttttt ctttggttcc gccttggtcc aacttcctcc ctgaaagact
    26041 tctaggaaaa gctggcagtc tctctcaggc gcaaattgat tgccacgatt gggtttgaaa
    26101 acaccttttt cccagagcca ttttagaagt cgctcgtcaa agtcactttt attgaccttg
    26161 attttttcct ttttctgagc ttttctggtt agattttcaa cctttctgag cagtttttct
    26221 tcctcttcca attgctggtc aagggacaat cgatgaaaat gacgaacaca gtcgctacca
    26281 attggaaaga ggcgttggcc tgtgacaccg ttaaagagtt cataagcgta tttgatggca
    26341 tttccacaga cacaattgct acggccgata ccgttaaaaa tcaaggaaac ttcattccat
    26401 tccttggtag cttgttccca agtatccgct ttcgaagcct gtaaaactgc atcgtgcagg
    26461 gattttctaa ctggaagtgt catgaggtct cctttctaat actcaataaa aatcaaagag
    26521 caaactagaa agctagtcgc agtcagctca aaacactgtt ttgaggttgt agatagaact
    26581 gacgaagtca gctcaaaaca ctgttttgag gttgtggata gaactgacga agtcagtaac
    26641 catatataca gcaaggcgaa gctgacgtgg tttgaagaga ttttcaaaga gtataagtta
    26701 tacttttaca acttgaacct cgtctttacc gagtaaaatc aagtattttt caatattttc
    26761 aatcgaatag gctcgtgata aagcctcttc gtatagagct aactgaccac gatagcggtc
    26821 tacgagttga cttggttcat catagcggtc tgtcttgtag tcgaacagaa caattttgtt
    26881 ttcgtaaagc agatagccat caaggatacc acggacaaca aagtcttcct gactcttttg
    26941 gtctcgtttg agcatggaga aaggttgctc gcgatagaga tggtcggtat tagcaagaat
    27001 ttcctgaccg agtactgtgt caaagaaagc aagaatttta tcaagattga tcttgtctct
    27061 gacagcttgg ctagtttgaa cttgtttgag tgtttctgtt aggctagcaa gggttagttg
    27121 ctggctgagg tcaattctct gcatgagttc gtgagtagca ctaccaatct cagctccagt
    27181 taccttttct ttggttgaaa aatctggcaa atcgaagctg attttcttgc ctactgactg
    27241 accttgacca gcaatctcga caccttccat atccataact ggttcgtaga atttcttgat
    27301 ttgacttggg gtttgaacac taggaagttc aatagctgcg cggtgaagag tattataaac
    27361 ttccacctcc ttcagcattt ccagagcttc tttgatggta tctgactgac gattgtctgc
    27421 ttgggagcta tcttggagag gactcttggt ttccaactct ccgatagctt ctctggtcaa
    27481 ctgatcttcg ccaataaaac gataactaaa gttgagcttg tccttagtaa acactttact
    27541 gatagcccaa agccaatctt ggaaattccg tgcttgcagt ctagtattgc tatttagttt
    27601 cccatttttg gctgctgggt attgcttgac ttccagcttt tcacgagaac ccttgccgac
    27661 aagatagagc tttttctcag cccgcgtcat agcaacatac agcaaacgca tctgctcaga
    27721 atagcttgct agctgtaatt cctcttcgtt ctgcctatag gtcagactag gaatggagag
    27781 tttgatggtt ttaggatagt ggtcttctac tgcccctgtc tccatcttgg caatatattt
    27841 gacaccaaga ccattctgac gactgagaat gacttctgac atagagtctt gcttgttgaa
    27901 atcttgatcc atattgagga taaagacgta aggaaactcc agccctttac tcttgtggat
    27961 ggtcatgagc tctactgcat cttttggcgg tgcgacggcc acgcttgcca aatcgtgctg
    28021 ggcttctaag acttggtcaa tcatacgaat aaaacgcgac aaacctttga aattgctctt
    28081 ttcaaattga tcagcacgca atgctagggc atagagattg gcctgcctag caggaccatt
    28141 cggcaaagcc ccaacatagt cataataaaa acggtcgttg taaatcttcc aaatcaagtc
    28201 atagagagag tgggttttgg catacaagcg ccaagaagct aggatatcca tgaattgctt
    28261 tagtttttca gctagagctg tgtgaatcaa gcctttttga ctacttgcca ttttttgtgc
    28321 attgaccagt ttctcataga gattttcgtg gactttatcc tctgctttct gaagggacaa
    28381 acgtgctagc tcatcctcat caaaaccaaa cattggagac ttcataaggg caaccaaggc
    28441 atagtcttgc aggggattgt gaatgacacg aagagtgttt agcatgactt gcacttctag
    28501 ggattggaga taattgtttt gctctccgtc agttttgaca ggaatcccgt actcagacag
    28561 ggcgaggaga atctggtcat tacgactgcg gctggaggtc agaagggcaa tttccttaaa
    28621 ggcaacacct ttttcttgat gaagtttcag aatctccttg ataactaagc gcatttcgcc
    28681 tgttagtttc gtttctgttt gactctcttc ttcctcacct gtatcgtcct tgtcgtagag
    28741 gagaaattct gccttgttgt ctggattggg agtcagtttg gtattggcaa aaacaagctg
    28801 gtgcttgtta tcatagttga tttcgccgac ctcttggtcc atgagacgtt caaagacatc
    28861 attggttgct gacagcactt ctgaactact acggaaattt tccttgagga gaatgagctt
    28921 gccttcttgg ggattttgcg catagcgttg gaatttctca ttgaaaatct gcgggtctgc
    28981 ctgacggaaa cgatagatgg attgcttgat atctcccacc ataaagcgat tgtggccatt
    29041 agacaacaat tccagcatcc gttcttgaat atggttggta tcctgatact catcgaccat
    29101 gacttcatgg aagcgctcct gataagactc acgaacttgt gggaaatttt ctaaaatctc
    29161 aatggtgtaa tggctgatat cagcgaattc aaaggcattt tcctgtcgtt ttctctgacg
    29221 ataagcctct acaaaatcgc tcatgaaaga ttggaaggtt ttagctagtt tccaagtgtc
    29281 tccatgataa cgttcttgat agtcgagaat cgctatctgg tctgataatt gtcctagttt
    29341 agtaaactgg gtctttctct cttcgttgta ggcatcagcc aggggcttca aatcagcctt
    29401 acggctggca ttagtcagag cacgaccgtt tttctcctta gagatgggga caacacgcgc
    29461 aagtactgcc tgataagcct gactatcgaa ctcctgattt agggagccaa tttcatccag
    29521 aattaactga acattttcta aataggcagc ctttgcaaac tccttggcat cgttatccag
    29581 atggtaacgg aaaaagcttt ccaaatccca gagggcttgt ttgatttgct cagtcagttt
    29641 ttctttttca ctggtaaaat cagctttctc aaagcctttg aggaaagatt cactcagcca
    29701 cttttgagga ttactggtgg attggaggaa gtcatagatt ttatagactt gctgccgcag
    29761 accccgttcg tccttgccac gcccagcaaa gtttttcagc aaatgactaa agctctcttt
    29821 ctgtttacct tggtaatgcg cttcaaagac ctcatgaaag acttcgtttt cgagaagaag
    29881 ttgctcgctt tggttttgta aaatacggaa attaggtgca atatcaagca gataaccatg
    29941 tttgccaagg aatttttgtg tgaaagagtc catggttccg atggcagcgt tgggtaggtc
    30001 tgccaactgg cgacccaagt gttgtttgag atcgacatca tctgtttctt ggattttctt
    30061 gctgattttt ttctctaaac gttctttaag ttcagttgca gccttgacgg taaaggttga
    30121 gataaagagt tgagaaattt cgacaccacg cgccaattgg tccagaatgc gctctaccat
    30181 gacaaaggtc tttccagaac cagccgatgc tgagaccagg atattctgac cagaagtgta
    30241 gatagcttcg atttgttcgg cagttttctt ctgttccttg ctcgaatttg cttctgcttc
    30301 ttgcagtttt tgaatctcct cctcacttaa aaagggaata agcttcatcg atttaactcc
    30361 tctcttattt tttcaaacca agcttgcttg agtttttctc cgaccagacg cttgccatca
    30421 gctaggtcca atttttctag gaaacgggct tggcccagat ggtaattggc ttcaaagcct
    30481 gtaatagcct gatgttgctg gacgtatggg gcaatgcttc tgccattttc agtataagga
    30541 ttgatggcga accggcctgc taaaatcttc tcagcagctt tcttgtaaag ataggcattg
    30601 tagtccagta ggagctgaaa ttcctcatct gtcagttgat tagccttgtt tttgttataa
    30661 aattcgccta aataactgct ttctttttcc aagaagagcc cttggtattt catagatttg
    30721 ctggcttcta ccactgctcc tgccagactt tttaccgcca tcagagattg gacaggttca
    30781 gccatttcca agtacatggc gccgaaaaag ttctgctccc cttctctttt tagggcagca
    30841 agataggttg gtaactgaga attgagccca ttaaagaaat gaggaaactg gaactgagtc
    30901 agactggatt tgtagtctac tactcctatc gctccattag ctttcaaacg gtcaatccgg
    30961 tccaccttgc ctcgtacaaa gacactgcgt ccattgtcta attgaataaa ggcttggtct
    31021 tttccaccaa aatttgcttc ttctttgatg gtttcgatgg ctggattgtg tcggagaata
    31081 tgtccagtcg tccgtgcaac atcaagcaaa acttccttgg taaactgggc ttccaaactt
    31141 tcttgataaa tagcttcaaa ttcgcgttct tgactggttt cttgaatagc ttgttctaga
    31201 cgttggtcaa aggaatcttc attaggcaac tgtaaggcgc gttcaaagat acgatgcaag
    31261 aaattcccgt gactacgggc atcaggacgc aaacgtaatt cctcctgcaa gcctaaaacg
    31321 tagcgtagga aataactgta ttcattgcga taaaactctg tcaaacccga cgtagacagg
    31381 taaaactcct gtttggcagg atagagagct tgcaaggtgt ccttggctaa ggtcttgctg
    31441 cttggactgg ttgggatagc tggattttcc agaccttgca gatctagttt tttacctatg
    31501 acacgcgaca gaaccttgac aaaagtcaaa tcttgctcag tatcgctcat ctcaccctgc
    31561 tggtgatagg caaccagact agacaaaaga ctgtgatagg accccatatc ctccttagac
    31621 agtcctttgt gattcatcct cttctctctc cgcctaaatc caaaatggat caactcttga
    31681 agataggcag attccttact ttcactttcg ttaaaaaggc ttggagccga caagaacaac
    31741 tgcttacgag cagaattgac caaggaaagc atagtgtagc gatttttctt gagattttca
    31801 ctgctggcaa tcagtaattg aacgccttct tcggtcgttt ggtttaggtt ttgcctttct
    31861 tcatctgtca gaagactggt gttttgagaa atttttggta aattgtcctg agttagtcca
    31921 atagcataga caaagtcagc agtcaatggt gcaatcaaat cgtaactctg caccagaaca
    31981 gtgtccactg ttgctggaat ggtacggtat tgggacaaac tcattccaga atggagcaag
    32041 gctaggaagt cttccagact aacctgtgaa ccagcaaaaa cagtcgcaaa ttgttctaaa
    32101 acatggcaga aagccttcca aacttcggct tgtctttcct gttctacagc ttccaaagtg
    32161 gttgtcaaat cttgtaactg cttggtcaca gctccttctt ttagaaagac actccatttt
    32221 tgtaggagtt tttcagcctt ttgttttcgg ctggcaaaga gggtttcaag aggtgctaaa
    32281 attctcaggc ggaggacatt caaacgctca agattaaatt ttccatggtg ggatttggtg
    32341 aaggtttgct gaaaggctgg caagccattg ataccaagat agcggatata ttgctcaaaa
    32401 gcatcaatat cagactgact gaggtcagta tacaaatcag ttctaagaag attaatcaag
    32461 tcctcctgac gaaaacggta acgttttaaa gctaaaatag actcgacaaa ctgagtcaag
    32521 ggatgatgag ccatggcttc gcttctacca agataaaaag gaatctgata ctggtcaaaa
    32581 atggttttga gagataactg gtaagaagct acatccccca agagaatacg aaaatgcttg
    32641 tagctcaggt ctgagttctc atgtaatttc tgacgaatgc tacgggctac tagctccaac
    32701 tcctcctttt gcgtcaaaca agaccagatt tgtaaatttt cacggtcttt ctcatcgaca
    32761 tccaaagcga gttctgaaaa gtcataagaa gactccaaca aacgagaggc cttgtcaaaa
    32821 ctatccatct tctcatgagt ttgagaacag tcctgagcag gcgtttggta tttagaagcc
    32881 agatgatgga gaaattttac gctggcttgg tagagattgc cctcgctaaa aggactggta
    32941 taggctttct tactagcata agccccgata acaatctcaa cacctttgcc gtgaagtaag
    33001 tccacaaccc gctcttcctc agcagaaaaa cgagtaaagc cgtcaatgac caaggtgatt
    33061 tgattaaaat cactacttac cttgtcattc tcaatagcct caatcaaatg ggacaactga
    33121 cttccctggg ctaactgacc ttgattaaga taggctgtta ctttctcaaa aatcaagagt
    33181 aaatccgtcc tcttatcctc atctgttaaa ttctccaagt ccaaaaaact catctgagat
    33241 ttggtcatct catggtaaag ctcaattaac tgctggatca attgaggatc ctgcttaata
    33301 gcgccataaa cacgcaagtc cttgggatcg agttcggcaa ggcatttgta aaaggccaac
    33361 ccaagaccga tatcatcaag agtagtttta actggtaaat cattcaagac cagataacga
    33421 gccatttgag caaagcgcgt gacggtaatc gaaaaagaag cctgctggga caagtattcc
    33481 agcacggcgc gttccttttc aaaagaaaga gagttggggg caatgtagaa gacccgcttg
    33541 ccagctgcaa ctagctcttc tgcctctctt gttagaattt ctgtcaaaga agtccgaata
    33601 tcagtataaa gtaatttcat ctcagcctcg ttggaatttt tcatcaccct atattatacc
    33661 atgattagcc tcgtaaatct gttaaaatat ttaggccatc ctttcttttc ttcatcatct
    33721 gctaaatctt aaatacttag ctttacttgt attagataga ataagtctgg ctactgaaaa
    33781 tcacataata aaaaagcctc ggtaacaagg ctttgagttt tatgattgtt tcttaggtac
    33841 ggaatacact tcaatgtgtt gtcccagtat cttaatgtcg acgggtagat tgtctgattt
    33901 atcgccatca acatcggact ctaattcgat atcagaagaa gttttaatat tacgtgcctt
    33961 tatatattca atattcttga tagaatgatt gaactatagt aaattgaaac tataacagta
    34021 caccgtggat gctaaaatat ttctagaaat taatttgatt tccctaatca agctgttcgt
    34081 atcttatttc aatctaatat agtaaaatga accaaaaata g
//
LOCUS       DBERPV010000019        33807 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.19, whole genome shotgun sequence.
ACCESSION   DBERPV010000019 DBERPV010000000
VERSION     DBERPV010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 33807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33807
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.19"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            217..447
                     /gene="blpU"
                     /locus_tag="ACL8C7_001191"
                     /pseudo
     CDS             217..447
                     /gene="blpU"
                     /locus_tag="ACL8C7_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
     gene            450..575
                     /locus_tag="ACL8C7_001192"
     CDS             450..575
                     /locus_tag="ACL8C7_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HGS1395399.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKKFLKSSEKKTEKSVKK"
     gene            1162..3315
                     /gene="comA"
                     /locus_tag="ACL8C7_001193"
     CDS             1162..3315
                     /gene="comA"
                     /locus_tag="ACL8C7_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter ComA"
                     /protein_id="HGS1395400.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFAEEWTGVTLFMAPSPDYKPHKEQKNGLFSFIPI
                     LVKQHGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLIVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            3328..4677
                     /gene="comB"
                     /locus_tag="ACL8C7_001194"
     CDS             3328..4677
                     /gene="comB"
                     /locus_tag="ACL8C7_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence pheromone export protein ComB"
                     /protein_id="HGS1395401.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTVKSAIETGASLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            4847..5554
                     /gene="purC"
                     /locus_tag="ACL8C7_001195"
     CDS             4847..5554
                     /gene="purC"
                     /locus_tag="ACL8C7_001195"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HGS1395402.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            5556..5699
                     /locus_tag="ACL8C7_001196"
     CDS             5556..5699
                     /locus_tag="ACL8C7_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HGS1395403.1"
                     /translation="MFATENLRLSTKRTQAEKVPQTFSLCRELGELTDVYEIVWEKLQ
                     GLK"
     gene            5756..9481
                     /locus_tag="ACL8C7_001197"
     CDS             5756..9481
                     /locus_tag="ACL8C7_001197"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HGS1395404.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVVSDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            9574..11016
                     /gene="purF"
                     /locus_tag="ACL8C7_001198"
     CDS             9574..11016
                     /gene="purF"
                     /locus_tag="ACL8C7_001198"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HGS1395405.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     CDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            11053..12075
                     /gene="purM"
                     /locus_tag="ACL8C7_001199"
     CDS             11053..12075
                     /gene="purM"
                     /locus_tag="ACL8C7_001199"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HGS1395406.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            12072..12617
                     /gene="purN"
                     /locus_tag="ACL8C7_001200"
     CDS             12072..12617
                     /gene="purN"
                     /locus_tag="ACL8C7_001200"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HGS1395407.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFAFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            12701..13194
                     /locus_tag="ACL8C7_001201"
                     /pseudo
     CDS             12701..13194
                     /locus_tag="ACL8C7_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
     gene            13219..14766
                     /gene="purH"
                     /locus_tag="ACL8C7_001202"
     CDS             13219..14766
                     /gene="purH"
                     /locus_tag="ACL8C7_001202"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HGS1395408.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKASPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            14888..16150
                     /gene="purD"
                     /locus_tag="ACL8C7_001203"
     CDS             14888..16150
                     /gene="purD"
                     /locus_tag="ACL8C7_001203"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HGS1395409.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVKKVFVVPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGIPTATYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHDMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNSRFGDPETQIILPRLTSDFAQNITDILDGKEPNITWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTVATVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            16407..16523
                     /locus_tag="ACL8C7_001204"
     CDS             16407..16523
                     /locus_tag="ACL8C7_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HGS1395410.1"
                     /translation="MKERLDDNPIVQGNWKTLGFQFRHETPLVAAAVPHKLR"
     gene            16553..17041
                     /gene="purE"
                     /locus_tag="ACL8C7_001205"
     CDS             16553..17041
                     /gene="purE"
                     /locus_tag="ACL8C7_001205"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009567721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HGS1395411.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            17028..18119
                     /gene="purK"
                     /locus_tag="ACL8C7_001206"
     CDS             17028..18119
                     /gene="purK"
                     /locus_tag="ACL8C7_001206"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HGS1395412.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDTVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            18129..18356
                     /locus_tag="ACL8C7_001207"
     CDS             18129..18356
                     /locus_tag="ACL8C7_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HGS1395413.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            18419..19717
                     /gene="purB"
                     /locus_tag="ACL8C7_001208"
     CDS             18419..19717
                     /gene="purB"
                     /locus_tag="ACL8C7_001208"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HGS1395414.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(19772..23710)
                     /gene="strH"
                     /locus_tag="ACL8C7_001209"
     CDS             complement(19772..23710)
                     /gene="strH"
                     /locus_tag="ACL8C7_001209"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored beta-N-acetylhexosaminidase StrH"
                     /protein_id="HGS1395415.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYDDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKESARTVNLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGDYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLNDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERELQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDHFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVIEKKLPETGTHDSAGLVVAGLMATLAAYGLTKRKED"
     gene            complement(24024..24740)
                     /locus_tag="ACL8C7_001210"
     CDS             complement(24024..24740)
                     /locus_tag="ACL8C7_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGS1395416.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            25088..26875
                     /locus_tag="ACL8C7_001211"
     CDS             25088..26875
                     /locus_tag="ACL8C7_001211"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HGS1395417.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYIAWNLHEPREGEFHFDGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEERGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            26872..27348
                     /locus_tag="ACL8C7_001212"
     CDS             26872..27348
                     /locus_tag="ACL8C7_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS1395418.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            27376..28281
                     /locus_tag="ACL8C7_001213"
     CDS             27376..28281
                     /locus_tag="ACL8C7_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGS1395419.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            28268..29083
                     /locus_tag="ACL8C7_001214"
     CDS             28268..29083
                     /locus_tag="ACL8C7_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGS1395420.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            29090..29494
                     /locus_tag="ACL8C7_001215"
     CDS             29090..29494
                     /locus_tag="ACL8C7_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGS1395421.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            29747..30913
                     /locus_tag="ACL8C7_001216"
     CDS             29747..30913
                     /locus_tag="ACL8C7_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGS1395422.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTTLLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVSLGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            31029..32066
                     /locus_tag="ACL8C7_001217"
     CDS             31029..32066
                     /locus_tag="ACL8C7_001217"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HGS1395423.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSITPDGVPAKTPEAN
                     RDVVKHIYNGTLLKDIFAEEDEQIQLASGLDHPFALPVGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            32274..33128
                     /locus_tag="ACL8C7_001218"
     CDS             32274..33128
                     /locus_tag="ACL8C7_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGS1395424.1"
                     /translation="MTYEYKSHIYLAETALNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            33278..33535
                     /locus_tag="ACL8C7_001219"
     CDS             33278..33535
                     /locus_tag="ACL8C7_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HGS1395425.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(33577..>33807)
                     /locus_tag="ACL8C7_001220"
     CDS             complement(33577..>33807)
                     /locus_tag="ACL8C7_001220"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395426.1"
                     /translation="NHIYGKVKLTWFEEIFEEYKSLHNKTHITKVLMNCTPKVRQKKS
                     NFLGSVHSTPDTMRFFNFKDFLQLLLTHIKLF"
BASE COUNT         9399 a         6554 c         7930 g         9924 t
ORIGIN      
        1 aactaggatt ctagttttgc aggaagtcta atagtaaaaa agtgattaga aaacatcttt
       61 tttaaaaata gagatgattt tgaaacaaaa aagctaattc aagacgtttc gatgccaatt
      121 caagatttgg atgaaaaaaa ttaatagata ctgttatact aaacttgtca agtttgtaac
      181 aagacaaata ttaaaaataa aaaagaggta ttcgttatga atacaaaaaa gatgtcacaa
      241 tttgaaatta tggatactga gatgcttgct tgagttgaag gtggcggatg caattgggga
      301 gattttgcca aagcaggtgt tggaggagga gcagcacgag gtcttcagct aggaattaaa
      361 acaagaacat ggcaaggtgc agcaactggt gctgcgggag gagctatact tggaggtgtg
      421 gcctatgcag cgacatgttg gtggtaatta tggattttaa aagttttatt attggtttag
      481 tagttggtat atttggtcct tatatggatg atttaattag aaaaaaattt ttaaagtctt
      541 cggagaagaa aacagaaaaa tctgttaaaa aataatcaaa actataaatg atgaatctga
      601 atcaaaatta ttttgcgcat gtaaagagga gtcttatagt aacgagtcaa aaaaggagta
      661 actatgaatc gtaatttaga acggtgttat ctattctgac taggaataga tcataccaga
      721 ggtagcttag aaatagcagg gacattagaa attgaagtaa taaataggat gtcgtaagtg
      781 ttactatcaa tgatttattt gtttcaagct tgcctagggt gacagtaaaa aatcaatttc
      841 ctttcaatag catattttta gtgggcagga ctcttgttct gcctattttt ttatccaaaa
      901 agtgcatttg ggagggagat aggcgcattt gggaaggaag tccagttttt gtttagtgat
      961 tggggtaaga tagttgttat cagatgagtt tatactcttc gaaaatcaaa ttcaaaccac
     1021 gtcaacgtcg ccttgccgta tatatgtgac tgacttcgtc agtcctatct acaacctcaa
     1081 aacagtgttt tgagcagctt gcggctagtt tcctagtttg ctctttgatt ttcattgagt
     1141 attagggaaa aggagatgaa tatgaaattt gggaaacgtc actatcgtcc gcaagtggat
     1201 cagatggact gcggtgtagc ttcattagcc atggtttttg gctactatgg tagttattat
     1261 tttttggctc acttgcgaga attggctaag acgaccatgg atgggacgac ggctttgggc
     1321 ttggtcaagg tggcagagga gattggtttt gagacgcgag ccattaaggc ggatatgacg
     1381 ctttttgact tgccggattt gacttttcct tttgttgccc atgtgcttaa ggaagggaaa
     1441 ttgctccact actatgtggt gactgggcag gataaggata gcattcatat tgccgaccca
     1501 gatcctgggg tgaaattgac caaactgcca cgtgagcgtt ttgcggaaga atggacagga
     1561 gtgactcttt ttatggcacc tagtccagac tacaagcctc ataaggaaca aaaaaatggt
     1621 ctgttctctt ttatccctat attagtgaag cagcatggct tgattgccaa tatcgttttg
     1681 gcaacactct tggtaaccgt gattaacatt gtgggttctt attatctgca gtctatcatt
     1741 gatacctatg tgccagatca gatgcgttcg acactaggga ttatttctat tgggctagtc
     1801 atcgtctaca tcctccagca aatcttgtct tacgctcagg agtatctctt gcttgttttg
     1861 gggcaacgct tgtcgattga cgtgattttg tcctatatca agcatgtttt tcacctccct
     1921 atgtccttct ttgcgacacg caggacaggg gagatcgtgt ctcgttttac agatgctaac
     1981 agtatcatcg atgcgctggc ttcgaccatc ctttcgattt tcctagatgt gtcaacggtt
     2041 gtcattattt cccttgttct attttcacaa aataccaatc tctttttcat gactttattg
     2101 gcgcttccta tctacacagt gattatcttt gcctttatga agccgtttga aaagatgaat
     2161 cgggatacca tggaagccaa tgcggttctg tcttcttcta tcattgagga catcaacggt
     2221 attgagacta tcaagtcctt gaccagtgaa agtcagcgtt accaaaaaat tgacaaggaa
     2281 tttgtggatt atctgaagaa atcctttacc tatagtcgag cagagagtca gcaaaaggct
     2341 ctgaaaaagg ttgcccatct cttgcttaat gtcggcattc tctggatggg ggctgttctg
     2401 gtcatggatg gcaagatgag tttggggcag ttgattacct ataatacctt gctggtttac
     2461 tttaccaatc ctttggaaaa tatcatcaat ctgcaaacca agcttcagac agcgcaggtt
     2521 gccaataacc gtctaaatga agtgtatcta gtagcttctg agtttgagga gaagaaaaca
     2581 gttgaggatt tgagcttgat gaagggagat atgaccttca agcaggttca ttacaagtat
     2641 ggctatggtc gagacgtctt gtcggatatc aatttaatcg ttccccaagg gtctaaggtg
     2701 gcttttgtgg ggatttcagg gtcaggtaag acgactttgg ccaagatgat ggttaatttt
     2761 tacgacccaa gtcaagggga gattagtctg ggtggtgtca atctcaatca gattgataaa
     2821 aaagccctgc gccagtacat caactatctg cctcaacagc cctatgtctt taacggaacg
     2881 attttggaga atcttctttt gggagccaag gaggggacga cacaggaaga tatcttacgg
     2941 gcggtcgaat tggcagagat tcgagaggat atcgagcgca tgccactgaa ttaccagaca
     3001 gaattgactt cggatggggc agggatttca ggtggtcaac gtcagagaat cgctttggcg
     3061 cgtgctctct tgacagatgc gccggtcttg attttggatg aggcgactag cagtttggat
     3121 attttgacag agaagcggat tgtcgataat ctcatggctt tggacaagac cttgattttc
     3181 attgctcacc gcttgactat tgctgagcgg acagagaagg tagttgtctt ggatcagggc
     3241 aagattgtcg aagaaggaaa gcatgctgat ttgcttgcac agggtggctt ttacgcccat
     3301 ttggtcaata gctagaaaga ggagaggatg aaaccagaat ttttagaaag tgcggagttt
     3361 tataatcgtc gttaccataa tttttccagt agtgtgattg tacccatggc ccttctgctc
     3421 gtgtttttac ttggctttgc aactgttgca gaaaaggaga tgagtttgtc cactagagct
     3481 actgtcgaac ctagtcgtat ccttgcaaat atccagtcaa ctagcaacaa tcgtattctt
     3541 gtcaatcatt tggaagaaaa taagctggtt aagaaggggg atcttttggt tcaataccaa
     3601 gaaggggcag agggtgtcca agcggagtcc tatgccagtc agttggacat gctaaaggat
     3661 caaaaaaagc aattggagta tctgcaaaag agcctgcaag aaggggagaa ccactttcca
     3721 gaggaggata agtttggcta ccaagccacc tttcgcgact acatcagtca agcaggcagt
     3781 cttagggcta gtacatcgca acaaaatgag accatcgcgt cccagaatgc agcagctagc
     3841 caaacccaag ccgaaatcgg caacctcatc agtcaaacag aggctaaaat tcgcgattac
     3901 cagacagtta agtcagctat tgaaacaggt gcttccttgg ccggtcagaa tctagcctac
     3961 tctctttacc agtcctataa gtctcagggc gaggaaaatc cccaaactaa ggttcaggca
     4021 gttgcacagg ttgaagcaca gatttctcag ttagaatcta gtcttgctac ttaccgtgtc
     4081 cagtatgcag gttcaggtac ccagcaagcc tatgcgtcag ggttaagcag tcaattggaa
     4141 tcccttaaat cccaacactt ggcaaaggtt ggtcaggaat tgacccttct agcccagaaa
     4201 atcttggagg cagagtcagg taagaaggta cagggaaatc ttttagacaa ggggaaaatt
     4261 acggcgagtg aggatggggt gcttcatctt aatcctgaga ccagtgattc tagcatggtt
     4321 gcagaaggtg ccctactagc ccaactttat ccatctttgg aaagagaagg gaaagccaaa
     4381 ctcacagcct atctaagttc aaaagatgta gcaagaatca aggtcggtga ttctgttcgc
     4441 tatactacga ctcatgatgc cgggaatcaa cttttcctag attcaactat tacaagtatt
     4501 gatgcgacag ctactaagac tgagaaaggg aatttcttta aaatagaggc ggagactaat
     4561 ctaacttcgg agcaggctga aaaacttagg tacggggtgg aaggccgctt gcagatgatt
     4621 acgggcaaga aaagttatct acgttattat ttggatcaat ttttgaacaa agagtaatgt
     4681 tcgtgttttt agagttaaat aatttttaaa ctgtgagaaa gattcttctt gcagtttttt
     4741 ctttacaatt tttgaaaaac atctactatt tattcggtta aattcttgtg ttttttggtt
     4801 ttttgtggta aaatgtgctc aagtaatacg aaaggcgaac tttaaaatgt caaaacaatt
     4861 gatctattcg ggaaaagcta aagatatcta tacaactgag gatgaaaatc ttattatttc
     4921 aacttacaag gaccaggcga ctgctttcaa cggtgtcaag aaggagcaga ttgcaggtaa
     4981 gggagtcttg aataatcaga tctcatcttt tatttttgag aaattaaatg cggctggtgt
     5041 ggcgactcac tttgtggaga aactttcaga cacggaacaa ctcaataaaa aggttaagat
     5101 tattcctttg gaagtcgtgc tccgcaacta tactgctggt tccttttcaa aacgttttgg
     5161 tgtggatgag ggaatcgcct tggagactcc gattgtcgaa ttttactaca aaaatgatga
     5221 tttggatgat ccatttatca atgatgagca tgtgaaattc ctacagattg cgggtgacca
     5281 gcagattgcc tacttgaagg aagaaacgcg tcgtatcaat gaactattga aagtctggtt
     5341 tgctgagatt gggcttaaat tgattgactt taagctagag ttcggttttg acaaggatgg
     5401 caagattatc ttggcagacg aattttcacc agataactgc cgcttgtggg acgctgatgg
     5461 caaccacatg gataaggatg ttttccgtag aggattggga gaactaaccg acgtttatga
     5521 gattgtttgg gaaaagttgc aggaattgaa ataatctgtt tgcaacggaa aaccttcgtc
     5581 tctcaactaa aaggactcag gctgaaaagg tcccccagac cttttcactc tgtagagaac
     5641 taggtgaact aacagatgtt tacgaaattg tctgggaaaa gttgcagggt ttaaaataac
     5701 aacctcaagg ctgtttggga atattgcaag agctgaaata aaggaataag aattgatgga
     5761 taaacgtatt tttgttgaaa aaaaggctga ttttcaggtc aagtcagaga gtttggttag
     5821 agagctccag cacaacttgg gactgtcaag cttgaaaagt attcgtattg tgcaagtata
     5881 tgatgtattt gacttggctg aggacttgtt tgcacctgca gagaagcaca ttttctctga
     5941 gcagggaacc gaccatgttt tagatgaagt atctgtgcag gcggatcttg ctaactatgc
     6001 tttctttgcc attgaaagtc tgccagggca gtttgaccag cgtgcagctt cgtcacagga
     6061 agccttgctt ttgttgggaa gttcgagtga cgtgacagtc aacacagccc aactttactt
     6121 ggtgaataaa gatattgatg cgactgagtt ggaagctgtc aaaaactacc tgctcaatcc
     6181 agttgattct cgtttcaagg atatcacgac agggattgcc aagcaggagt tttcagagtc
     6241 agacaagacc attccaaaat tgactttctt tgaaagctat acagcagaag actttgctcg
     6301 ctacaaggcc gagcaaggga tggccatgga agtggatgat ttgctcttta tccaagacta
     6361 ctttaagtca atcgggcgcg tgccaactga gactgaactc aaggttttgg acacttactg
     6421 gtctgaccac tgccgtcata cgacttttga gacagagttg aaacacatcg acttttcagc
     6481 ttctaaattt caaaagcaat tgcagtcaac ctatgacaag tatattgcca tgcgcgagga
     6541 gttaggtcgg tctgaaaaac cacaaacctt gatggatatg gcgactattt tcggtcgtta
     6601 tgagcgtgct aacggacgat tggatgatat ggaagtctct gacgaaatca atgcctgctc
     6661 agttgaaatt gaagtggatg ttgatggtgt caaggaacct tggctcctca tgtttaaaaa
     6721 tgaaacccac aaccatccaa cagaaattga gccatttggt ggagcggcta cctgtatcgg
     6781 tggagctatt cgtgatccgt tgtcaggccg ttcctatgtt taccaagcca tgcgtatttc
     6841 aggtgctggt gatattacag caccgatttc ggaaactcgt gctgggaaat tgccacaaca
     6901 agtcatttct aaaacagcag ctcatggtta ttcttcatat ggtaaccaga ttgggcttgc
     6961 cacaacctac gttcgtgaat acttccaccc aggctttgta gctaaacgta tggaacttgg
     7021 tgccgttgtt ggtgcggctc ccaagggcaa tgttgtccgt gaaaaacctg aagcaggtga
     7081 tgtgatcatc cttctcggag gcaaaacagg tcgtgatggt gtcggtggtg cgacgggctc
     7141 ttctaaggtt caaacagttg agtctgtaga gactgctggt gctgaggttc aaaaaggaaa
     7201 tgccatcgaa gaacgcaaga ttcagcgcct cttccgtaat ggcaatgtca ctcgtctgat
     7261 caagaagtcc aatgactttg gggcaggcgg tgtctgtgtg gctatcggtg aattggcaga
     7321 cggtcttgaa atcgacctca acaaggtgcc tcttaaatac cagggcttga atggtacaga
     7381 aattgccatc tctgaatcac aagaacggat ggcggtcgtg gttcgtcctg aagatgtgga
     7441 taccttcgtt gccgaatgta acaaagaaaa tattgatgct gttgtggtgg cgacagtaac
     7501 tgaaaaacca aatcttgtca tgcactggaa tggtgagaca atcgttgact tggagcgtcg
     7561 tttccttgac accaatggtg tgcgcgtggt tgtcgatgcc aaagttgtgg acaaggatgt
     7621 caaactccca gaagagcgtc aaacatctgc tgaaacactg gaatcagata cccttacggt
     7681 tctatctgac ctcaaccatg caagtcaaaa aggattacag actatctttg actgctctgt
     7741 tggacgctca acggttaatc acccacttgg tggtcgttac caactcacac caactgaggc
     7801 atctgtgcag aaattgccag ttcaacacgg tgtgactcat actgcgtcgg tcattgctca
     7861 aggtttcaac ccatatgtag ctgaatggtc tccataccac ggtgctgctt atgcggttat
     7921 cgaagcaact gctcgtttgg tggctgctgg tgccaactgg tctaaggctc gtttctctta
     7981 ccaagaatat ttcgagcgga tggacaagca agcagagcgt tttggtcagc cagtagccgc
     8041 ccttctaggc tctattgaag cacaaattca gcttggcttg ccatctatcg gtggtaagga
     8101 ctccatgtct ggtacctttg aagaattgac cgttccgcca accttggttg cctttggggt
     8161 gacgacggca gatagccgta aggtgctctc tccagaattt aaagctgttg gggaaaatat
     8221 ctactacatc ccaggtcaag ccctctctgc agagattgat tttgacttga ttaagaaaaa
     8281 ttttgctcag tttgaagcaa gccaagctga ccataaagtg acatctgcat cagctgtcaa
     8341 atacggtggt gtagttgaaa gtttggctct tgctaccttt ggaaactata ttggtgcaga
     8401 ggtgaccttg cctgaactta aaacagcttt gacagctcaa ttaggcggct ttgtcttcac
     8461 atctcctgaa gaaattgctg gagtagagaa gattggacaa acgaaagcag actttacact
     8521 gactgtcaac ggtgtgaagc tagatggaca caagcttgac agtgcatttc aagggacatt
     8581 ggaagaagtt tacccaacag aatttaccca agcgaaagaa ctagaagaag taccagctgt
     8641 ggtatcagat gttgtgatta aagccaaaga aaaggttgaa aaacctgtgg tttacattcc
     8701 agtctttcca ggaaccaact cagaatatga ttcagctaag gccttcgaaa aagaaggtgc
     8761 agaggtcaat ttggtgccat tcgtgacctt gaatgaagaa gctattgtca agtcagttga
     8821 aactatggtt gacaatatcg acaagactaa tattctcttc tttgccggtg gattctcggc
     8881 tgcggatgaa ccagatggtt cagctaagtt tatcgtcaat atcctgctta atgaaaaagt
     8941 gcgtgtggct attgatagct ttatcgcccg tggtggcttg attatcggta tttgtaatgg
     9001 attccaagcc ttagtcaaat cgggtctcct accatacgga aactttgaag atgctaacag
     9061 tactagtcca accctcttct acaatgatgc caaccaacac gtggccaaga tggtggaaac
     9121 tcgtattgcc aataccaact caccatggtt ggctggtgtg caagtgggcg atatccacgc
     9181 tattcctgtt tcgcacggtg aagggaagtt tgtcgtgacg gctgaggaat ttgcagagct
     9241 ccgtgacaat ggacaaattt tcagccaata cgttgacttt aacggtaaac caagtatgga
     9301 ttctaagtac aatccgaatg gttctgtcca tgccatcgaa ggaattacca gcaagaatgg
     9361 tcaaatcatc ggtaagatgg gccactcaga acgttatgag gatggtcttt tccaaaatat
     9421 cccaggcaat aaagaccaac acctgttcgc atcagcggtt aaacatttca ctggaaaata
     9481 agacttacag attttctaat agatagtatc agtaatgtaa aagtcatgta aatctagctc
     9541 ttgatgatta caaatgaaaa ttaggtataa aaaatgacat acgaagtaaa atctcttaat
     9601 gaagaatgtg gtgttttcgg tatttgggga catccagatg ctgctaagtt gacctatttt
     9661 ggactccaca gtcttcaaca ccgtggtcag gagggggcag gaatcctctc caatgatcaa
     9721 ggacaactga agcgccatcg tgacatgggg cttttatcag aagttttcag aaatccagcc
     9781 aatttggata aattgacagg agctggtgcg attgggcatg tgcgttatgc gactgctggc
     9841 gaagcttctg ttgataacat ccaacccttc ctcttccgtt ttcacgatat gcagtttggt
     9901 ttggctcata atggaaatct gaccaatgca gcctctctca agaaagaact ggaacaaaga
     9961 ggagcaattt tcagcgcgac ttcggactct gaaatcttgg ctcacctcat tcgtcgcagt
    10021 cataatccta gcctgatggg caaaatcaag gaagcgctca gtcttgtcaa aggtggtttt
    10081 gcctatatct tgctgtttga ggacaagttg attgcggctc ttgaccctaa tggctttcgt
    10141 ccgctttcta tcgggaaaat ggccaacgga gcggtggttg tttcctctga aacctgtgct
    10201 tttgaggtca ttggtgccga gtggatttgt gatttgaagc caggtgagat tgtgatcatt
    10261 gatgacgagg gcattcagta tgacagctat acagatgata cccagttggc gatttgttct
    10321 atggagtata tctactttgc ccgccctgat tctaatatcc acggtgtcaa tgtccatacg
    10381 gcacgtaaga gaatgggagc gcaattggcg cgagaattta agcatgaggc agatattgta
    10441 gttggtgtgc ccaattcttc cctaagcgcg gctatgggat ttgcggaaga atcaggctta
    10501 ccaaatgaaa tgggtctgat caaaaaccaa tacacccagc gaacttttat ccaaccgact
    10561 caagaattgc gggagcaagg agtgcggatg aaactgtctg ctgtttcggg tgttgtcaaa
    10621 ggcaaacgtg tggtcatggt ggatgattcc attgtacgtg gaacaacctc tcgtcgtatc
    10681 gttcagctct tgaaagaagc gggtgcgact gaggttcacg ttgccattgg aagtcctgca
    10741 ctagcgtatc catgtttcta cgggattgat atccagaccc gtcaggagct gattgcagcc
    10801 aatcatacgg tcgaagaaac tcgccaaatc attggtgcgg acagtctgac ttatctttca
    10861 attgatggct tgattgagtc gattggtatc gaaacagatg cgccgaacgg tggtctctgt
    10921 gtcgcttact ttgacggtga ctacccaacg cctctctatg actacgaaga agactatcgt
    10981 agaagtttgg aagaaaagac cagtttttac aagtaggcga cagattctcc attaaagaaa
    11041 aggaaaaaac aaatgacaaa taaaaatgca tatgcccagt cgggtgtgga tgttgaagcg
    11101 ggttatgaag ttgttgaacg gattaaaaag cacgtggccc gtacggagcg tgcaggtgtc
    11161 atgggagctc ttggtggctt tggtggtatg tttgaccttt ccaagactgg ggttaaagaa
    11221 cccgtcttga tttcagggac tgacggtgtc ggaaccaagc tcatgttggc tatcaagtac
    11281 gacaagcacg ataccatcgg gcaggactgt gtggccatgt gtgtcaacga catcattgct
    11341 gcaggtgcgg aacccctcta ttttctcgac tacgtagcga cagggaagaa tgaaccagct
    11401 aagctagaac aagtggttgc tggtgtggca gaaggttgtg tgcaggctgg tgctgccctc
    11461 atcggtgggg aaacggctga aatgccgggc atgtacggcg aagacgacta tgacttggct
    11521 ggttttgcgg tcggtgtggc tgaaaaatct caaatcattg acggttcaaa ggtggtagag
    11581 ggagatgttc ttctcggact tgcttcaagt gggattcact caaatggtta ctctttggtt
    11641 cgtcgtgtct ttgcggatta cacaggtgag gaagtcctac cagaattgga aggcaagaaa
    11701 cttaaggaag ttctacttga gccgactcgt atctatgtca aggctgtttt gccgctcatc
    11761 aaagaagagt tggtcaacgg cattgcccac atcacaggtg gtggctttat cgaaaatgtc
    11821 cctcgtatgt ttgcagatga cctagctgct gaaattgatg aaagcaaagt tccagtgctt
    11881 ccaattttca aagcccttga aaaatatggt cagattaaac acgaagaaat gtttgaaatc
    11941 ttcaatatgg gtgtgggact tatgttggcg gtcagccctg aaaatgtaga gcgtgtaaaa
    12001 gaattgttgg atgaagcagt ctatgaaatt ggtcgcatcg tcaagaaaga aaacgaaagt
    12061 gtcattatca aatgaaaaaa atagcggttt ttgcctctgg taatggctca aattttcagg
    12121 tgattgccga agaatttcca gtggagtttg ccttttcaga ccatcgtgat gcctatgtgc
    12181 ttgagcgtgc aaagcagctc ggcgttctgt cctatgcttt tgaactcaag gagtttgaga
    12241 gcaaggcaga ctacgaagca gcccttgtcg aactcttgga agaacaccag attgacttgg
    12301 tttgcctagc aggctacatg aaaatcgttg gaccaacctt attgtcggct tatgaaggtc
    12361 ggattgtcaa cattcatcca gcctacttgc cagaatttcc aggagctcat gggattgagg
    12421 atgcttggaa tgctggcgtg ggtcagtctg gtgtgaccat tcactgggtg gattcgggtg
    12481 tggatacagg ccaggtcatc aaacaggttc gtgtgccacg actagctgat gataccattg
    12541 acagatttga agctcgcatc catgaagcag agtacaggtt gtatccggaa gtagtgaagg
    12601 ctctatttac agattgactt tttgatgatt catatgatat ctttgatttt aaattggagt
    12661 cagtgtttgt tgaagacggc ttcaaactga ggtatttgta atgttagaat ctaaaaaaac
    12721 aactcgatat gtattttatg tctatctgat gttattaact tggggaatct tatttaagtt
    12781 tgaaacaaat cctgaattta tagcattttt cttagctcca aggtatatca attggattcc
    12841 attttcagaa ccactaatag tcgatggaaa aattgttttt gctgaaatgt tatttaatct
    12901 gatttccttt attccattag gtgtttgttt ccctttgata aaaactaatt tatctagttt
    12961 aagaatagtc gggacaggtt tcttgattag tttattgttt gagtgcttac agtatatttt
    13021 agcaataggt ataacagata taacggattt gactttaaat acgctaggtg tctgtgtagg
    13081 cttactgatt tatcaaattt ttataagagt gttcaaatca cagactagaa aatggatcaa
    13141 tatcttaggt atgcttatct tgttttactg ttactgcatt taattggtgt ttaactaatg
    13201 attaaaaagg agaatataat gactaaacgc gtcttaatca gcgtctcaga caaagcgggc
    13261 attgttgaat ttgcccaaga actcaaaaaa cttggttggg agattatctc aacaggtgga
    13321 actaaggttg cccttgataa tgctggggtg gataccattg ctatcgatga tgtgactggt
    13381 ttcccagaaa tgatggacgg tcgtgtgaag accctccacc caaatatcca cggagggctt
    13441 ctcgctcgtc gtgacttgga tagccacttg gaagcggcta aggacaacaa gattgagctc
    13501 attgaccttg tggtggtcaa cctttaccca tttaaggaaa ctatccttaa accagatgtg
    13561 acttatgctg atgcagttga aaatatcgat attggtgggc catctatgct tcgttcagca
    13621 gcgaaaaatc atgccagtgt tacagttgtg gtagatcctg ctgactacgc tgtggttttg
    13681 gacgaattgg cagcaaacgg cgaaacctct tatgaaactc gccaacgttt agcagccaaa
    13741 gtatttcgtc acacagcggc ttatgacgcc ttgattgcag aatacttcac agctcaagtg
    13801 ggtgaaagca agcctgaaaa actcactttg acttatgacc tcaagcaacc aatgcgttac
    13861 ggtgagaatc ctcaacaaga cgcggacttt taccagaaag ctttgcctac agactactcc
    13921 attgcttcag ccaaacagct caacgggaaa gaattgtcat ttaataatat ccgtgatgca
    13981 gatgctgcta tccgtatcat ccgtgacttc aaagatagtc caaccgttgt ggctctcaaa
    14041 cacatgaatc catgtggaat tggtcaagct gatgacatcg agactgcttg ggactacgct
    14101 tatgagtctg acccagtgtc tatctttggt gggattgtcg tcctcaaccg tgaggtggat
    14161 gctgcgacag ctgagaagat gcacggcgtt ttcctcgaaa tcatcattgc accaagctat
    14221 acggatgaag cgctagccat tttgatcaat aaaaagaaaa acttgcgtat ccttgccttg
    14281 ccatttaatg ctcaagaggc tagcgaagtg gaagcagaat acacaggtgt agtcggtgga
    14341 cttctcgtgc aaaatcaaga cgtggtcaag gcaagcccag ctgactggca agtggtgacc
    14401 aaacgtcagc caaccgagac agaagcgact gctcttgagt tcgcttggaa ggctatcaag
    14461 tacgtcaaat caaatggcat tatcgtgacc aacgaccaca tgacacttgg tgttggtcca
    14521 ggtcaaacca accgtgtggc ttctgttcgc cttgccattg accaagccaa agatcgtctg
    14581 gacggggcgg tccttgcttc agatgccttc ttcccatttg cggataacgt ggaagaaatc
    14641 gccaaagcag gaattaaggc catcatccag cccggtggct ctgtccgtga ccaagaatcc
    14701 atcgaagcag cggataaata cggcttgact atggtcttta caggtgtgag acattttaga
    14761 cattaagaag ataaaaggga agaaaacagt ttctttcctt ttttggctta aaatgctaac
    14821 tgaaacaaga ttaaaacgaa cttttttgat ataatgttgg taaataattc gcaaaagagg
    14881 ttgaggaatg aaactgcttg ttgtcggttc tggtggtcgt gagcatgcga ttgctaaaaa
    14941 gttacttgaa tcaaaagacg tgaaaaaagt ctttgtagtt cctgggaatg atgggatgac
    15001 tctggatggt ttggaattgg taaatatctc tatttccgaa cattctaaat tgattgactt
    15061 cgcaaagacc aatgatgttg cttggacctt tatcggtcca gatgatgccc ttgctgctgg
    15121 tatcgtggat gattttaacc aagctggact taaggccttt ggtccgacta gggctgcagc
    15181 ggagctggag tggtccaagg attttgccaa ggaaatcatg gtcaaatacg gcattccgac
    15241 agcaacctat ggcacatttt cagatttcga ggaagcaaag gcctatatcg aaaagcatgg
    15301 tgcgcctatc gtagtcaagg cggatggctt ggcgcttggg aagggtgtcg tcgttgctga
    15361 gacggttgag caagcggtcg aagccgctca tgatatgctt ttggacaata aatttggtga
    15421 ctcaggtgcg cgcgtggtta ttgaggaatt ccttgaagga gaggaatttt cactctttgc
    15481 ctttgttaat ggtgataagt tctacatcat gccaacggct caggaccaca aacgtgccta
    15541 cgatggcgat aaagggccta acacgggtgg tatgggtgcc tatgcgccag ttccacactt
    15601 accacagagt gtagttgata cagcggttga caccattgtc aagccagttc tagaagggat
    15661 gattaaagaa ggtcgccctt atctgggagt tctttacgca gggcttatct tgacagcaga
    15721 cgggccgaag gtcatcgagt tcaactctcg atttggagat cctgaaactc agattatctt
    15781 gcctcgctta acctctgact ttgcgcaaaa tatcacggat attctggatg gcaaggagcc
    15841 aaacatcact tggacggaca agggtgtgac tctgggtgtg gttgttgcat ccaagggtta
    15901 cccgctagac tatgaaaggg gcgttgagtt gccagccaag acagaaggcg atgtcatcac
    15961 ctactatgca ggggctaagt ttgcggaaaa tagcagagca ctgctctcaa acggcggacg
    16021 agtttatatg ctggttacca cagtagccac cgtcaaagaa gcccaagcca gcatctacca
    16081 agaactatcc caacaaaaaa tagaaggact cttctaccga acagatatcg gaagcaaggc
    16141 aattaagtaa agatataaga ataacgcgac gcagtcgcca aatacgataa tggtcgtcgt
    16201 ggtgaaaaga ccagaacagt gaatgttctg gtcaagggga aactttgaga ccttaggctc
    16261 aaagtttagg aatgaaaccg aaggtttgct tccgcctcca tcacctaaga ccattatcaa
    16321 aaagaaaaat aaaaattcac aaaatacgtt aatggtcgta tggtttgcga gcgttagcga
    16381 gctaatatag aataatcacc gccgttgtga aagaacgatt ggatgacaat ccaatcgttc
    16441 agggaaattg gaagaccttg ggtttccaat ttaggcatga gacacctttg gtggctgctg
    16501 ccgtccctca caagctaagg tgattgttga aaaagaggaa aaaggagaag aaatgaaacc
    16561 agtaatttcc atcatcatgg gctcaaaatc cgactgggca accatgcaaa aaacagcaga
    16621 agtcctagac cgcttcggtg tagcctacga aaagaaagtt gtttccgcac accgtacacc
    16681 agacctcatg ttcaaacatg cagaagaagc ccgtagtcgt ggcatcaaga tcatcatcgc
    16741 aggtgctggt ggcgcagcgc atttgccagg catggtagct gccaaaacaa cccttccagt
    16801 cattggtgtg ccagtcaagt ctcgtgctct tagtggagtg gattcactct attctatcgt
    16861 tcagatgccg ggtggggtgc ctgttgcgac catggctatc ggtgaagctg gagcgactaa
    16921 cgcagctctc tttgccctcc gtctcctctc tgtagaagat aagtccattg cggatgcact
    16981 tgccaacttt gctgaagaac aaggaaaaat cgcagaggag tcgtcaaatg agctcatcta
    17041 aaacaatcgg aattatcggt ggcggtcaac tgggtcagat gatggccatt tctgctatct
    17101 acatgggcca caaggttatc gcgctggatc ctgcggcgga ttgcccggcc tctcgcgtgg
    17161 cggaaatcat tgtggcacct tataacgatg tggacgccct ccgtcagttg gcagaccgtt
    17221 gcgatgtcct cacttacgag tttgaaaatg tcgacgctga cggtttggat accgttatca
    17281 aggatggaca actccctcaa ggaacagatc tgctccgcat ttcgcaaaat cgtatttttg
    17341 aaaaggactt tttgtcaaac aaggctcaag tcactgtggc accctacaag gtcgtgactt
    17401 ctagcctaga cttggcagat atcgacttgt cgaaaaacta tgtcctcaag actgcgactg
    17461 gtggctacga tggtcatgga caaaaggtta ttcgttcaga agcagacttg gaagcagcct
    17521 atgcgctagc agactcagca gactgcgtct tggaagaatt tgtcaacttt gaccttgaga
    17581 tttctgtcat cgtgtcagga aatggcaagg aggtgacgtt tttcccagtt caggaaaata
    17641 tccaccgcaa caatatcctg tctaagacca tcgtaccagc ccgcatttct gaaagtctag
    17701 cagacaaggc taaagctatg gcagtgcgaa tcgcagaaca actcaacttg tctggaactc
    17761 tctgtgtgga aatgtttgcg actgatgatg acgttattgt caatgaaatc gccccacgac
    17821 cacataactc tgggcactat tctattgaag cctgtgattt ctctcagttt gacacccata
    17881 ttctgggtgt tctcggagca ccattaccag tcatcaaact ccatgcgcca gccgttatgc
    17941 ttaatgtcct cggtcagcat gtcgaggctg ctgagcaata tgtgacagaa aattcaagcg
    18001 cccacctcca catgtatggt aaaatagaag cgaagcacaa ccgcaagatg ggacatgtga
    18061 ccttgtttag tgatgtaccg gatagtgtgg atgagcttgg ggaagggatt gatttttagg
    18121 acaagtctat gatacaaatt atcgttaata catttattga aaaggataag actggagcag
    18181 ttgttgaagt gttgtatgcc agtgctgacc aagataaggt acaagctaaa tatgaagaac
    18241 tagctgcaca ataccccgaa aattatttag ctatctatga tgtaccgctg gatacggatt
    18301 tgaatacact agatcattac ccgtctgtgt ttattgaaaa agaggagttt gagtagaaat
    18361 cttggtttac ctagatagct tattcccaac agcttaagaa gaaaggaaaa attaacacat
    18421 gatcaaccgt tactctcgcc ctgagatggc gaatatttgg agtgaagaaa ataaataccg
    18481 tgcttggctt gaggtggaaa tcctctctga cgaggcatgg gctgagttgg gggaaatccc
    18541 taaggaagat gtggctttga ttcgcaagaa ggcggacttt gacatcgacc gtattttgga
    18601 aattgagcag gagacgcgcc acgatgtggt ggctttcacg cgtgcggttt ctgagactct
    18661 tggtgaagag cgcaagtggg ttcactatgg gttaacttct accgacgtgg tggatactgc
    18721 ttatggttac ctctacaagc aggccaacga catcatccgt cgtgaccttg aaaacttcac
    18781 taatatcatc gctgacaagg ccaaggagca caagttcacc atcatgatgg ggcgtactca
    18841 tggtgtgcac gctgagccga caacctttgg tcttaaattg gcaacttggt acagcgaaat
    18901 gaaacgcaat atcgagcgtt tcgagcatgc agctgctggt gtagaagctg gtaagatttc
    18961 tggtgcggtt gggaactttg ccaatatccc accatttgta gaggagtatg tctgcgataa
    19021 acttggcatc cgtgcccaag aaatctctac acaagtcctt cctcgtgacc ttcacgctga
    19081 gtactttgcg gttcttgcca gcattgcgac ttcaatcgaa cgtatggcga ctgagattcg
    19141 tggtctacaa aaatctgagc aacgcgaagt agaagagttc tttgctaaag ggcaaaaagg
    19201 gtcttcagca atgcctcaca aacgcaaccc aatcggttct gaaaatatga ctggtctggc
    19261 gcgtgtcatt cgtggtcaca tgattacggc ttatgaaaac gtcgctctct ggcacgaacg
    19321 cgatatttct cactcatcag ctgagcgtat catcacacca gatacgacca ttttgattga
    19381 ctacatgctc aaccgttttg gaaatatcgt caagaacttg acagtcttcc cagaaaatat
    19441 gatccgaaac atgaactcga cttttggtct tatctttagc caacgggcta tgttgacatt
    19501 gattgaaaaa ggcatgaccc gtgagcaagc ctatgacttg gtgcaaccaa aaacagccta
    19561 ctcttgggac aaccaagtag actttaaacc acttcttgag gcagattcag aagtaacatc
    19621 acgtctcact caagaagaaa tcgatgaaat cttcaaccca gtttattaca ccaaacgagt
    19681 ggatgatatc tttgaacgtc ttggactagg tgattaatta aaaaataaac agcgagcttc
    19741 aatctcgctg tttatttttt atcgaaaaga cttagtcttc ttttctttta gtgagtccat
    19801 aggctgctag tgtggccatg agtcctgcga ctactagtcc tgcagaatcg tgagttcctg
    19861 tttcaggaag ttttttctct attaccacag gagctggatc ttgaggaaga gctttgcttt
    19921 cctcagcagg agcagttgat ggagctggtt ggcttgggat ttctagtttt ggtttttctt
    19981 cagcaatagc ggcttgtccg ttttcatcgc ctacatgtgt taccatagtt ccgacttcga
    20041 ctatttgagt aacggcttcc tgtgctacga cactatttac aagtgttttc acttccttac
    20101 catcggcaga agtgctcaca gagtagaagt tgctacgatg tccattgacg cccttagtaa
    20161 tgacttgtgt ttttcctttg agtaagagtg gattttcacg agtcactgtg gtaaatggaa
    20221 tttcttcttt ttggatatcc agtctaggtt ttacctcagt agttggtgca agaccacttt
    20281 catcaccctt gtgagttaca ggagcgccaa cttcaaccac ttggtttata acttctttgg
    20341 ttacctggct atcaaggact gtttctgttg tttttccatt ttcagtgagt acagagatgt
    20401 aatgagttcg ctcacctttg actcctgctg tgataatatt ttcctgacca gctgggaggt
    20461 taggattttc tttcttgata acttcaaatg gaatttcttc agttcttgtg atgagttctg
    20521 gtctggtttc aacattggca gccacttcat tttcatccag gcttcctgaa tgagttgcag
    20581 ctggtttgag gccttgaaga gcggctttta ggttggctac aagtgtgtca agctcagctt
    20641 gtttattacg gttgaggttg taatttagag ctgttttagc tgcgtcaagg gcctcaagac
    20701 tttctttact atatccttct aagtttgtag gaattttagc taattcttcg cggagagcat
    20761 tataattagc acggaagtgg tctttgttgt ggtctgcaaa ggcagtcatg agttcaaaga
    20821 tttcctcttc cttgtattca gcgcttggtc tatctgccca gattgaaagc atacttccga
    20881 ctgttggaag atctacttca ggatatttgg tagaagctag ttgattgaat ggtgtttttc
    20941 cagtattctc aatagctttc ttgaggaaac caccaccatc ttctggtttt tgaccaagaa
    21001 tgtagtacca gtcaccgttg gtattcaaga atttatagcc tttgcttgct aggtattgag
    21061 gtgatgcgag gttatatccc caccagcctt tagaccagta agaaatcaag acatctttgt
    21121 caaactgaac atcgtccttg tcttcatagt agaagccatc gttgaaggcc attggttgaa
    21181 gctctctttc tttggccata gctgcgaggg tgttggcata ttcggcaaat ttgccataga
    21241 gttgatacca cttgaggtag taccagcctt gggcactagt cgcatcgttg gcgtattcgt
    21301 cagtaccaaa gttgaaaatc tttgttttac ctgcaaagaa gtccatgtat ttaccgatga
    21361 gggcttttac aaagttcatc gcttcttcgt ttttcaagtc catagttgtt tttgaaactt
    21421 tatcaaagtg ggcttgagga tttttaatac ctaatttttc catggcaacc agcatagcat
    21481 ccatgtgacc tggactgtta atagctggga tgagaccgat gtccttagat ttagcgtatt
    21541 caattagctc tgtcacttct gcctgtgtta gtgcagtacc gtttggatcg tcgtagtaag
    21601 ctttagttcc ttcgataata gcttttttaa cgtcatcact agcataggtt tttccgttgg
    21661 cagtaatggt catatcattg agtagaaagc gaagtccgtc atttcctaga aggagatgga
    21721 catcagaata tccgagctca ctggccttgt ctacgatgcg tttgagctgg ttcagagtaa
    21781 agtatttgcg tccagcatcg attgagatta ccttgttttt ggcaagtttt tcaacctcac
    21841 gtttagcttc ttcttctttt tgagcttcag gcgtgagggt caagttgttg acagtttctt
    21901 gaagtttagc aatggcttga tcaatcgtat cttgttgggc acggctaagg ttgctatcga
    21961 gagagcgaat agctttttca gcttctttta cggccgtgac gctttctgca gtataacggt
    22021 tcaggtcttt tggtacctcg ttaagtgctt gctctgcaga ttcataatca gctgcgaagt
    22081 attcagcgtt ggcatttgca aaatgacgca tgagtttgaa gaggcgtgat ggtgaataac
    22141 gtgcagatgg agtgtcagcc caagcagcta ccataccacc gatgattggg atatcagctc
    22201 cttctgtttt tggtacagaa gtgattggtg tgtttttaat accattgagc ccctgatcga
    22261 gattgtacca gccttggcca tcagcgtttc gtccaagaac gtagtaccaa gcatcattgg
    22321 tattaaggat ttggtgacct ttttcagcta gtagtttaga agaagcgaca tcgtagtctc
    22381 cccaaccacc agtccacata gaaacgatga tgtctttgtc aaaactacca aagcttgtgt
    22441 cgctattgta gtagataccg tcgttaaagg ccattggttt gagaccgtgc gattttacaa
    22501 tacgagcgag gtcattggcg taggcaataa atttttcata gccttttaca gggtagcctt
    22561 cgtttggata gtatttatca gcttgaagca cactccaacc tttagcatct gtcgcatcat
    22621 tggcatattc atcaagtccg atgttgaaga tttcagtctt tttcgcgaaa taagcagcat
    22681 acttgtcgat aagggctttt gtaaaagcga cagcttgttc gttgtcaaga ttgacagtac
    22741 gggctgattc cttcccaaaa tagctaaagt tagggttttg gattcccaat tctttcatgg
    22801 cattgagaat cgcatccatg tgcccaggac tatttactgt cggaatgaga ccgatacctt
    22861 tatctttggc atagttaatc agatctgtca tttgactttc tgttaagtga ttgccgtttg
    22921 gatcgtcgta ataatcattt gtaccttttt caatggcgcg tttgacatcg tcactggcat
    22981 aggtcttgcc gttagctgtg atgctcatat cgtccaacat gaaacggagt ccatcatttc
    23041 cgactaatag gtgtaaatca gtgtagccat aatgtttcgc tttatcgatg atttccttga
    23101 gctgttctgg tgagaaatat ttacgtccag catcaataga aacaattttc tttttcgcta
    23161 gtttttcatt tacagttgca gcacgttcct ttcctgcctc tgtttccggt ttgtcagcct
    23221 ctgctttcgc ttcatctttt ttagctggtt tatccttgtc agtcttgtct gtatttgact
    23281 ctttagaatc aacctctttc gcttcttcct ttttagggct agcttcttct gcctttttat
    23341 tagcagtttc tttttcagca gaagttggag ttaccacttc tgctttatca ctaggagttg
    23401 aactaacttc ctcttgtggt ttttcttctg tttttggaag actagctacc ttatcagtag
    23461 ctggagtttc tgtttctaca gtttttggag cttctggttg aagctctgct ttaggtgttt
    23521 cctcagtccg attttcggat gattgagggg aatcagaaac cgtatggatg gtcggttggt
    23581 tttctgtagt agtaggagta actccatcgg ctgcaacagt ctgtgcttgg aaggcaaatc
    23641 caattagaac agaagctgct cctacagcgt atttacgaat agaaaaacgc tgttgttttt
    23701 catgtttcat tgcaaaacct cctgattgca ttgttatatt gatagcgatt atataaatca
    23761 acgcctttat tttatttctt atattaacga gagtcaagag gagatgacaa aaaactataa
    23821 taagtataaa aaaatataaa atttaaactt aagatttcag attggtcgaa aaatacatat
    23881 atatatctag tataattttt ggttctattt ctataaaata ttccacaaat tatagaatct
    23941 tccaaaaata ggtaagcgct acctttttgg tgtggtataa taagcataga aaaagcccga
    24001 gcgattaggc tcaggctttc ttcttagtga tcacggtcac atgagatgaa tttaatcttg
    24061 tagtaatcag atcgtttgta agtttcactg tattctaaaa cttggccagt tgattcgagt
    24121 ttggtgattt tagtttgtag gacagtaggg aattgttcat cgactccgag gactgaagcc
    24181 gcatgttctg gagttggaaa gactatttcg ttgatttctt caaagtgttc atcattcatg
    24241 tgaatgtggt agtctaactt gaaacgatta tagatagaac tatagtattc aaggtttgga
    24301 taatttgcgt tgatatattg ttctgggatg taggatgtat ggtagatata aacgacaccg
    24361 tttgattcgc ggatacgttc aatcttgtag tagaattgat cgccgcgtag acccaatttt
    24421 tccaagtaaa caagcttgtt tccgcgttca attgaaagaa cagttacctt atcatcttta
    24481 gcattgaaga gttcaatatc tgaaaactct acaagcttgt gtttgcgtgc acgtgaaacg
    24541 aaggttcctt ttccttgttg gcggacaata tagccatctt tggcaaggtc gtttaaggcg
    24601 cgaacaactg tgatagagct gacatcgtac attgaaatga gttctgcttc agtgtaaaat
    24661 ttatctccac tgctaaactg cccagagatg attttatttt ttaattcgtc ttttatgtat
    24721 tgatatttgg gaattgccat atttttacct ctattttcct tctccataga aaattttacc
    24781 ataaaagcga aaaaaatagt agtcttttga ataaaaaatt agaataatag tttgaaaaat
    24841 taagcgatat agggattgct catattttat caatgtattc tatacaaaat tattttaggt
    24901 cctatattcc gaatttaaag agcgtttgaa atgggtctaa aaatgtttga aactaattga
    24961 atgtgtgtat aatagtaaaa atgcagtaaa tatcccgaca atttctattg acaattcaaa
    25021 cagattggtt tataattaat ataacaacaa atgaaagcgc aaactttcgc ggtcggaagg
    25081 tagttttatg acacgatttg agatacgaga tgatttctat ctcgatggaa aatcatttaa
    25141 gattttatct ggtgccattc attattttag ggttcctcca gaggattggt atcattcgct
    25201 ctataacttg aaggctcttg gttttaatac ggtagagact tatattgctt ggaatttaca
    25261 cgagcctcgt gaaggtgagt ttcattttga cggtgatctg gatttagaga aatttctcca
    25321 aatagcgcag gatttgggtc tctacgcaat tgtgcgtccg tctccattta tctgtgcgga
    25381 atgggaattc ggtggcttac cagcttggct cttgaccaag aacatgcgaa ttcgctcatc
    25441 cgacccagca tatatcgagg cagttggtcg ctactatgat cagttattgc caagactggt
    25501 gcctcgtttg ttggacaatg gtggcaatat tctcatgatg caggttgaaa atgagtatgg
    25561 ttcttacgga gaagataagg cttacctgag agcgattcga cagctaatgg aagagcgtgg
    25621 cgtaacctgt cctctcttta catcagatgg tccatggcga gctactctga aagctggaac
    25681 cttaattgaa gaggacctct ttgtaacagg aaactttggt tctaaggcac cttacaactt
    25741 ttcgcagatg caggaattct ttgatgaaca tggtaagaaa tggccactca tgtgtatgga
    25801 gttctgggat ggttggttta atcgctggaa agaaccgatt atcacacggg atcctaagga
    25861 attggcagat gcagttcgag aggttttgga acaaggctct atcaatcttt acatgttcca
    25921 cggtggtaca aactttggtt tcatgaatgg ttgctcggct cgaggaactt tggacctgcc
    25981 acaagttacg tcttatgatt acgatgccct tctggatgaa gaaggaaatc caactgctaa
    26041 atatcttgca gtcaagaaga tgatggcaac acatttttca gagtatccgc agttggaacc
    26101 actctacaaa gagagtatgg agttggatgc tattccacta gttgaaaaag tttctttgtt
    26161 tgaaacctta gatagcttgt caagtcctgt agaaagtctc tatcctcaaa agatggagga
    26221 gctgggacaa agttatggct acctacttta tcgaacagaa acaaactggg atgcagaaga
    26281 agaaagactt cgtatcattg atggtcgaga tagggcccag ctgtatgtcg atggtcagtg
    26341 ggttaaaact caatatcaga cagagattgg ggaagatatt ttttatcaag gtaaaaagaa
    26401 agggctatct aggttagata tcttgataga aaatatgggg cgtgtcaact atgggcataa
    26461 gttcttagcg gatacgcaac gtaagggaat tcggacaggg gtctgtaagg atctgcattt
    26521 cttactaaac tggaaacact atccacttcc actagacaat cctgagaaaa ttgatttttc
    26581 aaaaggatgg actcaaggac aaccagcctt ttacgcttat gactttacag tcgaagagcc
    26641 aaaagatact tacctagact tgtctgagtt tggtaaggga gttgcctttg tcaatgggca
    26701 gaatctagga cgtttttgga acgttggccc aactctctca ctttatatcc ctcatagcta
    26761 tctcaaggaa ggtgccaacc gcatcattat ctttgaaaca gaaggtcaat ataaagaaga
    26821 gattcattta actcgtaaac ctacactaaa acatataaag ggggaaaact tatgacaatt
    26881 gtaggatgcc gtattgatgg acgtttgatc cacggacaag tagccaatct ttgggctgga
    26941 aaactaaatg tttcacgcat tatggttgta gacgacgaag ttgtcaacaa cgatattgaa
    27001 aagagtggtt tgaaacttgc gacaccacca ggtgtgaaat tgagtatttt gccagttgag
    27061 aaagctgcag ccaatattct tgctggtaaa tacgatagcc aacgtctctt tatcgtggct
    27121 cgtaaaccag accgcttcct tggcttggta gaagcaggtg taccacttga aacccttaat
    27181 gttgggaata tgtctcaaac accagaaact cgttctatta cacgttctat caacgtagta
    27241 gacaaggatg tggaagactt ccacaaactg gcagaaaaag gtgttaaact tactgctcag
    27301 atggttccaa atgatccaat ttcagacttt ttgagcttat taaaatagga aaaaaatttt
    27361 taggaggtca ttgttatgat acaatggtgg caaattttac ttctcacttt gtactcagct
    27421 tatcaaatct gtgatgagtt gacgatcgtt tcatctgcag gttcccctgt atttgctggt
    27481 ttcattactg gtttaatcat gggagatgtg actactggtt tacttatcgg tggtaacttg
    27541 caactgttcg ttcttggggt tggtaccttc ggtggtgctt ctcgtatcga cgcaacttct
    27601 ggtgcggttc ttgcgacagc cttctctgtt tcacaaggaa ttgatgcacc gcttgcaatt
    27661 actacaatcg ctgtaccagt agcagctctc ttgacttact tcgacgttct tggtcgtatg
    27721 actactacct tcttcgctca ccgtgtggat gccgcaatcg aacgctttga ctataaaggt
    27781 attgaacgca actacttgct tggtgcgatt ccgtgggctc tatctcgtgc ccttccagtc
    27841 ttctttgccc ttgcttttgg tggtgccttt gtacaatcag tagtagactt cgttgaagcc
    27901 tacaaatggg ttgcagatgg cttgacactc gcaggacgta tgcttccagg tcttggattt
    27961 gcaatcttgc ttcgttacct tccagttaaa cgtaaccttc actaccttgc tatgggattt
    28021 ggtttgacag ctatgttgac tgttctttac tcatatgtaa caggtcttgg tggcgctgtt
    28081 gctggtatcg taggtactct tcctgctgaa gttgctgaaa aaattggttt cgtgaacaac
    28141 ttcaaaggtt tgtctatgat tggtatttct atcgtaggta ttttccttgc agtgcttcac
    28201 ttcaaaaata gccaaaaagt agctgtagca gcaccttcta caccatcaga aagtggggaa
    28261 atcgaagatg acgaattcta attacaaact tacaaaagaa gattttaatc aaatcaacaa
    28321 acgtagcttg tttactttcc aattaggttg gaactacgaa cgtatgcaag cttctggtta
    28381 cctttacatg atcttgcctc agttgcgtaa aatgtatggt gatggaactc ctgaattgaa
    28441 agaaatgatg aaagttcata ctcaattctt caatacttca ccattcttcc ataccattat
    28501 cgctggtttt gaccttgcca tggaagaaaa agatggtgta ggttcaaaag acgctgttaa
    28561 cggtatcaag acaggtttga tgggaccatt cgctcctctt ggggatacaa tctttggttc
    28621 acttgtacct gctatcatgg ggtcagtcgc agcaactatg gctatcgctg gccaaccttg
    28681 ggggatcttc ctttggattg cagttgcagt agcgtatgac atcttccgtt ggaaacagtt
    28741 ggaatttgct tacaaagaag gggttaacct tatcaacaac atgcaaagta ccttgacagc
    28801 tttgattgac gctgcatctg tacttggtgt cttcatgatg ggtgctcttg tagcaacagt
    28861 gattaacttt gaaatttctt acaagttgcc aatcggtgaa aagatgattg atttccaaga
    28921 catcttgaac caaatcttcc cacgtttgct tccagcaatc tttactgcct ttatcttctg
    28981 gttgcttggt aaaaaaggta tgaactctac taaagctatc ggtattatta tcgtacttgc
    29041 tttggctctt tctgcccttg gtcactttgc acttggaatg taattcctta tgactaaatc
    29101 attaattttg gtgagccatg gtcgcttctg tgaggagctt agaggtagca cagaaatgat
    29161 tatgggccca caagacaaca tttacacagt agctcttctt ccagaagatg gcccagaaga
    29221 atttactgct aaatttgaag ctgttattga aggattggat gatttcctag tctttgcgga
    29281 tcttctcggt gggacacctt gtaatgtggt gagtcgcttg atcatggaag gtcgtgatat
    29341 tgacctttac gcagggatga atcttccaat ggtgattgaa tttatcaatg cgagccttac
    29401 aggcgcagat gcggactaca agagccgtgc tgcagaaagc attgtgaaag ttaatgacct
    29461 gttagcgggc ttcgatgatg acgaagatga ataatactct tcgaaaatct cttcaaacta
    29521 cgtcaacgtc gccttgccgt aggtatatgt tactgacttc gtcagtctta tccggcaacc
    29581 tcaaagcggt gctttgagca gcctgcggct agtttcctac agattttagt tggaactcga
    29641 ttcaattcat gtgacaacgt gaaaatcgtt agagcatttt atatagaata tacatgggaa
    29701 tggagcttac tcccattccc atatttaata gaaaaagagg aactcaatgc tacattatac
    29761 aaaagaagac ttgctcgaat tgggtgcaga aatcactacg cgtgaaatct accaacagcc
    29821 tgatgtatgg agagaagctt ttgaatttta tcaagcaaaa cgtgaagaaa ttgcagcctt
    29881 cctacaagaa atcgctgata aacatgacta tattaaggtt atcttgacag gtgctgggac
    29941 ttctgcttat gtgggagaca ccttgctacc ttactttaag gaagtctatg acgaacgcaa
    30001 atggaatttc aatgctattg cgacaacaga tatcgttgcc aatccagcaa cctatttgaa
    30061 aaaagatgtg gcaactgtcc ttgtgtcttt tgctcgtagt gggaactcgc ctgaaagtgt
    30121 ggcgactgtt gatttggcca aatccttggt ggatgagctt tatcaagtga cgattacttg
    30181 tgcagcagat ggtaaattgg ctcttcaagc tcacggtgat gaccgtaatc tcttgctctt
    30241 gcaaccagct gtctctaatg atgctggatt tgccatgact tctagcttta cgtctatgat
    30301 gttgacaact ctcttggtct ttgatcctac agaatttgct gttaagtctg aacgttttga
    30361 agttgtatct agtcttgccc gtaaagtttt agacaaggca gaagatgtca aagagctcgt
    30421 tgatttagac tttaaccgtg tcatctatct aggcgctggt cctttctttg gacttgctca
    30481 tgaagctcag ctcaagattt tggaattaac tgctggtcaa gttgcgacca tgtatgaaag
    30541 cccagttggc ttccgtcacg gtccaaaatc tcttatcaac gacaatacag ttgttttggt
    30601 ctttggtaca acgacagact atactcgtaa gtacgacttg gacttggttc gtgaagttgc
    30661 tggtgaccag attgctcgtc gtgttgtgct tttgagtgat caagcttttg gtcttgaaaa
    30721 tgtcaaagaa gtgtcccttg gttgtggcgg tgtcttgaat gatatttacc gtgtcttccc
    30781 ttacatcgtt tatgcccaac tctttgccct attgacttca ctcaaggtag aaaataaacc
    30841 agatacaccg tctcctacag gtacagtaaa ccgtgtagta caaggtgtca taattcacga
    30901 atatcaaaag taagacagtg tttatgaatt cttgacaaga ggatttgtaa attatcagat
    30961 aaaccataga ttgtcagtac gctttctatg gtttgtttgc ttgagagaaa tagtaaaagg
    31021 agaacagaat gaaagcatac acagagcgtg tatttggaaa tgttgagggc gaggatgtct
    31081 tggcctatcg atttgagaca gacggtggct accaacttga ggttatgact tatggcgcga
    31141 ccatcttgcg ctatgtcgca cctgacaagg ctggaaattt tgccaatgtt atcttgggat
    31201 ttgatgactt tgatagttat gtaggcaata gtcccaagca tggagcaagt gtaggtcctg
    31261 tagcgggtcg tattgcaggt gcgacctttg agctcaatgg taagacctat gaccttgagg
    31321 ttaataatgc tagcaactgt aatcacagtg gttcaactgg ttgggattcc agcttgtttg
    31381 aagttgaaga agtaagcgat catggcttga ctctctacac agaacgtaca gatgggacag
    31441 gagggttccc tggaaatctc aagatttgga tcagttatca cttggaagaa actggtgcct
    31501 atgaaattag ctacaaggta acgaccgatc aggatacgct ggtcaatcca accaaccaca
    31561 gctatttcaa cttgtctggt gatttcacgc agacgattga ccgtcatgtc ttccaactaa
    31621 acacagaggg catttactca atcactcctg acggtgttcc tgccaaaact ccagaagcca
    31681 accgtgatgt ggtcaaacac atctacaatg gtaccttgtt gaaggatatc tttgcagaag
    31741 aagatgagca aatccagctg gcatcaggtt tggatcaccc atttgccctt cctgtaggcc
    31801 atgacaatgc tggattcctt tatgaccaaa attcaggtcg cttcctgctt ttcaagacag
    31861 aagctccttg ctttgtggtc tacacagcaa actttgtgga tgaaagtgtc atcataggag
    31921 gtcagccaat gctacagcac aatgggattg ctcttgaagc gcaagcttta ccagatgcca
    31981 ttcacagtga ccttaaaggc caagtcattc ttaaagctgg tcaaaccttc accagtaaga
    32041 cacgttatga acttgttgtg aaataaaaaa agctggtcaa aaagtcttta aaattaaaat
    32101 aatgcatatt gtcaggtgat ggaaagtttg ataatatgcg ttttattata aaatgattta
    32161 ctttatctta tcctgaaatg gtgttatttt tgagttatct ggcttgactt tcttgatgaa
    32221 aattatataa tagttgtaac aataataatt acaacgagaa aagaggacca tttatgacct
    32281 atgaatacaa gagtcacatt tatttggcag agacagcttt aaatgtaaag gatttggcca
    32341 gtcaaacagc cttttatcag caagttattg gtttagaaat cttatctcaa actgagacag
    32401 agtccattct aggccttggt ggaaaagtct tggtacagct gattcaagca caagagagcg
    32461 gagaagtgag ggaacattat ggtctttacc atttggccat tctcttgccc acacgcaagg
    32521 ctttggctga tgtcttgaaa cacctgacag atttacagat tcctcttgtc ggcggtgcag
    32581 accatggtta cagtgaagct atttacttgg aagatttgga gggaaatggc attgaactct
    32641 atcgagataa gccagtttcc acatgggata ttcgagaaga tggacgcatt atcggagtga
    32701 cagaggctct tgcggcgcag gacatttatg agttggggga aagagtagag ccctttatcc
    32761 tggcagaagg tacgagaatg gggcatattc atctttccgt caaggatagt cgaaagtcca
    32821 gccagtttta tcaaaaggtg ttagggctag aggataaatt cagtgtgcct agcgctagtt
    32881 ggattgcggc tggagattac catcatcatt tagcagttaa cgaatgggga ggaaaaggtc
    32941 tggcttcgcg taagcaaggc ttaccaggtt tagcctacta tgtcatcgaa gtcgcacata
    33001 aaaaagaact attaacgatt gcccaacgag cacaagaagt tgacgcacca atcaaatgga
    33061 tgacatcgag ccaattggaa atcacagact cagatggcat cgtgacccgt attcgtttag
    33121 caaggtaaaa ttaggaattt ttaataagtt ataagtattg ctagtttgct ttttgaacgg
    33181 tctttggtaa cagaactgcg tgagctggat gggcgagaat tttgacaaag aagctgatta
    33241 gagatataat gaagaaaaat cgagcaagga aaaagaaatg acaaattcaa agtatattac
    33301 ttgtttgaaa cgttcagagg gccagttgtg tgggattcaa aagatgattg aaggagatcg
    33361 tgactgtgct gatattgtga cgcaactgac agcagtgaga tctagtgtag agcgcgtgat
    33421 tgagatgata attaccgaaa atcttactga atgtatcaat cagccactag atgattctga
    33481 agctcaaaag gaacgcctag aaaaggctat ccgatacttg attaaacgga aataaatgaa
    33541 tgttttgaga cgatatgtgc aaaggtctat taactattag aatagtttaa tgtgagtcaa
    33601 aagaagttgt aaaaaatctt taaaattaaa aaaacgcata gtatcaggtg ttgaatgtac
    33661 tgaccccaaa aagttagatt ttttctgtct aacttttggg gtgcagttca taagaacctt
    33721 ggtaatatgc gttttattat gtagagactt atactcttcg aaaatctctt caaaccacgt
    33781 cagtttcacc ttgccgtaga tatggtt
//
LOCUS       DBERPV010000020        33428 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.20, whole genome shotgun sequence.
ACCESSION   DBERPV010000020 DBERPV010000000
VERSION     DBERPV010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 33428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33428
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.20"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(381..1361)
                     /locus_tag="ACL8C7_001221"
     CDS             complement(381..1361)
                     /locus_tag="ACL8C7_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HGS1395427.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTPPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            complement(1876..3891)
                     /gene="recG"
                     /locus_tag="ACL8C7_001222"
     CDS             complement(1876..3891)
                     /gene="recG"
                     /locus_tag="ACL8C7_001222"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HGS1395428.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKYLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKASLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQVYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            complement(3910..5013)
                     /gene="alr"
                     /locus_tag="ACL8C7_001223"
     CDS             complement(3910..5013)
                     /gene="alr"
                     /locus_tag="ACL8C7_001223"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HGS1395429.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(5003..5365)
                     /gene="acpS"
                     /locus_tag="ACL8C7_001224"
     CDS             complement(5003..5365)
                     /gene="acpS"
                     /locus_tag="ACL8C7_001224"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HGS1395430.1"
                     /translation="MIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLKGR
                     RQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLSIS
                     HTDQFVTASVILEENHES"
     gene            complement(5410..6441)
                     /locus_tag="ACL8C7_001225"
     CDS             complement(5410..6441)
                     /locus_tag="ACL8C7_001225"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HGS1395431.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            complement(6443..7474)
                     /locus_tag="ACL8C7_001226"
     CDS             complement(6443..7474)
                     /locus_tag="ACL8C7_001226"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HGS1395432.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPELFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(7555..10068)
                     /gene="secA"
                     /locus_tag="ACL8C7_001227"
     CDS             complement(7555..10068)
                     /gene="secA"
                     /locus_tag="ACL8C7_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HGS1395433.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYTQRYDVITADRDL
                     APEIQAMIKRTIGRVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(10214..10501)
                     /locus_tag="ACL8C7_001228"
     CDS             complement(10214..10501)
                     /locus_tag="ACL8C7_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395434.1"
                     /translation="MLNLKSFITRYSKVYIGLVLLIWIAFFFLPWGSPILGGKIDLFS
                     IQKVLLVFGILSILMALLSKKVSLFVFGLICCLSLWINLFILFAILPILGN"
     gene            complement(10495..11070)
                     /locus_tag="ACL8C7_001229"
     CDS             complement(10495..11070)
                     /locus_tag="ACL8C7_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase"
                     /protein_id="HGS1395435.1"
                     /translation="MKTIVKICLVALSAFLLLFAGKNVFADSNSHDNLNSLEVSDRSF
                     RNGELLKSYLVKDKDRIYFDYDKAVQDKQAKDVIDMGLLVETISEDYSSNTFTPAKYF
                     KAGLPVHGNYCGPGYNGEGFTLPVVDVLDQGCQNHDRCYKWGAGIGANCECNRQLVDF
                     IKVNRRWIPESALWVADAIRVYFETIGAIGC"
     gene            11532..12383
                     /locus_tag="ACL8C7_001230"
                     /note="rgg1518"
     CDS             11532..12383
                     /locus_tag="ACL8C7_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator
                     Rgg1518"
                     /protein_id="HGS1395436.1"
                     /translation="MRWDYGQIFKEIRKSKGLTQQDVCGQVIHRTTLTNIEHGKVIPS
                     FENMVFLLEQIDMSLAEFKYIWNEYHPSKRRDIIVESQNPSTFQDTRKMVELTEKCQK
                     YLKTHHDVPIQNIYRHTKIVTELRTKGFKNNHVLKDLSEEIWDYLEPMDTWYISDLKL
                     LGTILFFFPSENLPLLIDRIMKTIEKYKYFRETKVFLSSFLANLSTVYFQHHLFKECE
                     TITLQLLVLAEELKIYDILGFSQVRLGILQHNSDLIDKGITLLRLTKEEALVEILEKE
                     INDFSNL"
     gene            complement(12605..12955)
                     /locus_tag="ACL8C7_001231"
     CDS             complement(12605..12955)
                     /locus_tag="ACL8C7_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395437.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLAYVFFKKMLDLRRE
                     LGKSKGVHKGRCRN"
     gene            complement(13096..13431)
                     /locus_tag="ACL8C7_001232"
     CDS             complement(13096..13431)
                     /locus_tag="ACL8C7_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395438.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(13522..14832)
                     /gene="der"
                     /locus_tag="ACL8C7_001233"
     CDS             complement(13522..14832)
                     /gene="der"
                     /locus_tag="ACL8C7_001233"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HGS1395439.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(14846..15559)
                     /locus_tag="ACL8C7_001234"
     CDS             complement(14846..15559)
                     /locus_tag="ACL8C7_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HGS1395440.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYKLVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            complement(15556..16452)
                     /gene="dnaI"
                     /locus_tag="ACL8C7_001235"
     CDS             complement(15556..16452)
                     /gene="dnaI"
                     /locus_tag="ACL8C7_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HGS1395441.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKGKNGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(16453..17622)
                     /locus_tag="ACL8C7_001236"
     CDS             complement(16453..17622)
                     /locus_tag="ACL8C7_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGS1395442.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLVLHAPLSSQD
                     FLEHPVYRRLLEKKIGDVAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLDHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKAKIQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            complement(17623..18096)
                     /gene="nrdR"
                     /locus_tag="ACL8C7_001237"
     CDS             complement(17623..18096)
                     /gene="nrdR"
                     /locus_tag="ACL8C7_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HGS1395443.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            18236..18601
                     /locus_tag="ACL8C7_001238"
     CDS             18236..18601
                     /locus_tag="ACL8C7_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGS1395444.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            18606..19301
                     /locus_tag="ACL8C7_001239"
     CDS             18606..19301
                     /locus_tag="ACL8C7_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1395445.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            19318..20085
                     /locus_tag="ACL8C7_001240"
     CDS             19318..20085
                     /locus_tag="ACL8C7_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395446.1"
                     /translation="MFWNLVRYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(20438..21637)
                     /locus_tag="ACL8C7_001241"
     CDS             complement(20438..21637)
                     /locus_tag="ACL8C7_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1395447.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGILNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEV
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKGLPFLAQSGILVHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINDYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(21634..22527)
                     /locus_tag="ACL8C7_001242"
     CDS             complement(21634..22527)
                     /locus_tag="ACL8C7_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1395448.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            22650..22841
                     /locus_tag="ACL8C7_001243"
     CDS             22650..22841
                     /locus_tag="ACL8C7_001243"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395449.1"
                     /translation="MKSKEQTRKLAVGCSKYSFEVADKTDEVSSKHCFEVVDRTDEVS
                     NYIYGKAKLTWFEEIFEEY"
     gene            23209..23422
                     /locus_tag="ACL8C7_001244"
                     /pseudo
     CDS             23209..23422
                     /locus_tag="ACL8C7_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            23837..24454
                     /locus_tag="ACL8C7_001245"
     CDS             23837..24454
                     /locus_tag="ACL8C7_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HGS1395450.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(24774..25661)
                     /gene="scrK"
                     /locus_tag="ACL8C7_001246"
     CDS             complement(24774..25661)
                     /gene="scrK"
                     /locus_tag="ACL8C7_001246"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HGS1395451.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(25810..27693)
                     /locus_tag="ACL8C7_001247"
     CDS             complement(25810..27693)
                     /locus_tag="ACL8C7_001247"
                     /EC_number="2.7.1.211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="HGS1395452.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEVKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTGDYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            28069..29523
                     /locus_tag="ACL8C7_001248"
     CDS             28069..29523
                     /locus_tag="ACL8C7_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HGS1395453.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAIQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDCFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            29504..30469
                     /locus_tag="ACL8C7_001249"
     CDS             29504..30469
                     /locus_tag="ACL8C7_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS1395454.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(30505..31779)
                     /locus_tag="ACL8C7_001250"
     CDS             complement(30505..31779)
                     /locus_tag="ACL8C7_001250"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HGS1395455.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVEQLIADKTFNLETAQRYLENLRS"
     gene            complement(31779..32951)
                     /locus_tag="ACL8C7_001251"
     CDS             complement(31779..32951)
                     /locus_tag="ACL8C7_001251"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HGS1395456.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(33082..33330)
                     /locus_tag="ACL8C7_001252"
     CDS             complement(33082..33330)
                     /locus_tag="ACL8C7_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395457.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
BASE COUNT         9786 a         7497 c         6245 g         9900 t
ORIGIN      
        1 aacatatata cggcaaggcg aagctgacgt ggtttgaaga gatttttgaa aagtattaac
       61 acctacagac aagcctaacg atagcaagaa ctaccctact cgataggtat cggcttttgc
      121 tttctgaaaa aaattatttt aagcaatttg acaaatctag caacaaaaaa ttctataaat
      181 ataatagatt gacactagaa tagtacacat ttgtttctaa aacattgtta gaaatcgatt
      241 tgactgtcct gatcgatttg tcctgttctt gtttcatttt actatatttc catgataaaa
      301 cgcatagtat caagtttttt taatcccctg atactatgcg tgtttgtaat ttttaagatt
      361 ttgtgcttag agtcgactcc ttattttaga tatttaaaag gaatctcact tccacagagc
      421 cagttgtaga cttggtcatt gacaaataca ttcatggctt cgtgagcata ctcaggcatg
      481 atacgatagg ttttatcgca ggtcagacga ttataaatcg caaactgggt aatgggatag
      541 caaacatcgt cgtccaagcc cgtaatcatc ttaacctcac cttggatacg atgggcaaga
      601 tttttgacat cgatataggc aagggtcgcc atgatttcct cctctgtttc atggaagggg
      661 tcgtgaaact tgaaataacg gaaaagttcg tcgtaagcct cgctagtatt accaatttca
      721 atcacccgtc tgaagtctga caagaaggga taaatggcaa ctgttttctg aattcgagga
      781 ttgagcgctg ctgcaactag agctagagcc cctccttgtg aggcaccata actagaaaga
      841 cgcttctcat caacctgaga cagactagca acaatttcga ccaactggta aatatccaga
      901 taaacatcct tataaaagag gtggtcccga ccttccatag caccacggat aatatgcccc
      961 ttcacggtat ttcctaaagg agaacgcaag ccgtcttgtg agtaacctga ctggccccgc
     1021 acatccatgg aaacaacacc gtaaccagct acggtgaagc ccagcatgtc ggcccagtcc
     1081 cagccacgtc ccatataacc atgaaaatgg aagattagtg gaaccttctc ctcactcttt
     1141 ggaagaacaa tgcgtgcata gacctttcct tccttgcttc cttcaaatgt taactcatag
     1201 cacttgactt gaggaatgtg gaaatctctt tcctccaagt ggtaggatgg aggtgtggaa
     1261 acatttttca cttccccatc ccagaaagca tcaaagtctt ccggaacctc atcccttcct
     1321 ctataggtct taatttcttc tagcaaagct ggatttttca tagcatgctc cttttatttt
     1381 gtaatcgtta ccacaactgt agcatatcta tgtaatcaat gcaagaaaga agggtaaata
     1441 gaaagtgaat ttagattctt tacttttagg atgatgggct gaaagtagtt ttagaaacga
     1501 aaaaagagca tttcgctctc tcttctgttt atactagttt tttgcttcct tcttttggaa
     1561 agtggtttgg taatttactt taatcgttac tgtcatatga gagtcctcgt ttctttttga
     1621 tgactctagt ataagagcca aacctaaaaa ctagcttaat actcttcgaa aatctcttca
     1681 aaccacgtca gcgtcgcctt accgtatata tatgttactg acttcgtcag ttctatctgc
     1741 cacctcaaaa cggtgttttg agctgacttc gtcagtttca tccacaacct caaaacagtg
     1801 ttttgagcaa cctgcggtta gcttcctagt ttgctctttg attttcattg agtataagtt
     1861 ttccttagag aaagcttaat ccagatgttc tttcttttcc agatgaaggg caatcatgcg
     1921 ccactctgga tcttcttgcc aagcttctat agaactaatg tagctagcaa cctttcttgc
     1981 ttcttctaaa atcggaaaat cttcgataat atcagccact tggaactctg gaagtcctga
     2041 ctgtctggtt ccaaaaatct caccagaacc acgcattttc aaatcttcct ccgcaaggac
     2101 aaatccattg gtcgtttctg tcatgatacg catgcggtct ttcccagaat ccgtcttggg
     2161 attagcaacg agaacagcgt aggactgctt gtccccccga ccgacacgac ctctaagctg
     2221 gtgaagttga ctgagaccga agcgatcggc atccatgata atcatgacag tcgcattggg
     2281 aacgttgacc ccaacctcaa taaccgtcgt cgaaaccaga atatccgtct ttctctcctt
     2341 gaaatcctgc atgatctggt ctttttcgtc actcttcatc ctaccatgta gaagagccac
     2401 ctctgccttg cctgcaaaat gagtcgtcaa ctcctctgat aaggcaatgg catttttcaa
     2461 atctagagct tctgattctt caatcaaagg agagatgaca tagacttggg aacctttttg
     2521 aatttccccc tctaaccaag tcaagacctg aggtagttgc tcatgtttga tccagcgcgt
     2581 cacaataggc ttccgacctg ctggcatctg gtcgataatg gaaacatcca tatctccaaa
     2641 ggctgtgatg gcaagcgtcc gtggaatggg agtcgccgtc atcatgagga catctggatt
     2701 gtcacctttt tcccgtaaaa tacgcctttg ccctacacca aaacggtgct gctcatcgat
     2761 aataatcaaa ccaagacgag catactccac cccatcttgt atcagagcgt gagttcctat
     2821 aatcaaatca gcctcaccct tggcaatggt ctccaagact tctctctttt ctgcagcttt
     2881 caaggaacct gtcaagagag ccagtttcaa attgggaaaa aggttctgta aactctcaaa
     2941 gtgttgctct gcgaggattt ctgttggtac cattagggca gcctgataac ctgctgtcac
     3001 tgccgcaaac atggccaagc cagcgactac cgtttttcca ctccccacat ccccttgtag
     3061 gagacgattc atgtggtggt cggacttcat atcagttaaa atttcctgca aactcttttc
     3121 ctgagcttgg gtcagggcaa aaggaagact tgctttaact gctgtcactt tttcctgaga
     3181 ccaattcaga accagaccac ttccctgaac tctattttca gacttgagca tctgcagctg
     3241 catttggaaa taaaagagtt cctcaaactt tatacggcga agagcctgct tgtattctgc
     3301 caaatacttt ggaaaatgca tagcacggac tgcctgacaa cgggacatga gtttgtattt
     3361 gtctagtaaa gactggggca gattttcttc tatcaagagg tccagtccct gatcaaaagc
     3421 cgtcttgatg accttgacca gactggcctg actgattccc tgagccagac gatagacagg
     3481 ctggaggtca tcttctacct gagccagaac cttcatccca gtcagactag ccttagcgcg
     3541 gtcccatttt ccaaagacag caagggttgc tcccaactct attttatcag ccagataggg
     3601 ctggttaaag aaattcaccg caaaaacgac ctctccctgc ttgagactaa aacgcaggcg
     3661 attgcgcttg aaaccataat actggacact agcaggagtc actacctgac cagaaagaac
     3721 tgccttctca ccgtcttcca gctccagcac ctgcttggtt ttgaagtctt cataacggaa
     3781 aggaaagtag agcaagagat cttgcaagtt ttcaattcct agtttggcgt atttttctgc
     3841 tgactttggt cccacaccag gcaagacatg caagggttga tgtagattca tgctccactc
     3901 ctttcttttc taataatatt ctctcggaat acggtcgctg aggaggcaaa ccacctcata
     3961 gttaatggtt acgcggtagg tcgctacctg agttgcagtg atttccttat ccccattgga
     4021 gccaatcaag gttaccttgg ttcctagcgg ataaagctta ggcaatcgaa tagtgatttg
     4081 gtccatcgaa accctgccga caattgggca agcttggcca tctaccaaga cagagaaatt
     4141 ttgcatgtct cttgtccatc catctgcata cccgattggc acggtcgcga tgacttgctc
     4201 gctatccgct tgataagttg ctccatagcc catgcaagct ccagctggaa ctgtcttgac
     4261 atgaaccaga gcagactcca aggtcaaggc cggtatcaaa tcataaggca aatccaagac
     4321 cgctccactt ggattgaggc catacatggc atctcccata cgaaccgcat tgaaaatagt
     4381 ctctacatgc caaagagtcg ttgcagaatt gctagcatga accagctctg gaacttcctt
     4441 catactagct aaaatagttt taaaccgttc taactgggca ttaaaatagt catctgattc
     4501 ctcatcagca gtagcaaagt gggtaaagat tccttcaaca caaacaccgt gttgttggag
     4561 caaatcttga gcctgctcaa cctcacttgc ctctctaaaa ccaatccgtc ccatccctga
     4621 atcaatcttg aggtggactg tcaatccagt taggtccact tccttatcta agagtgcttg
     4681 aatccactcc agtccagcca ctgtcaaggt gaagtcatat tctttagcta gagcaacagc
     4741 ttcgatttca gaaactccta aaatgaggat tggcttgctg agtccagctt gtctgagttc
     4801 aatggcttca tcgatattgg aaacgcaaaa gccatcaaca tcatcttgaa ttgccttggc
     4861 aacggcaaca gctccatgac cataagcatt ggccttaacc acagccaact tgagcgttcc
     4921 ttgagggata tgagccccca tttgctgaat attttgtcga atagctccca gatgaatcag
     4981 agccttggtt ggtctatgtg gactagcttt catgattttc ctccaaaatg acactggctg
     5041 tcacaaactg atcggtgtgg ctgatagaca gccaaatctt tcctgaaaat ggtgcctgac
     5101 taaaataagg cgccccacgt tcattgttca agacttccaa atcctgaaaa ccgagcttgc
     5161 taatgcccgt tcccatagcc ttggaaaagg cctccttagc cgaccagcga ccagctaaat
     5221 attctatttg cctgcgtcct ttgagactgg tgaagcgctc catttcctga gcggtcagta
     5281 cacgcttagc aaatccttca tgtcgtgtaa ctgcgctttc tatcgaagcc aattcttcga
     5341 tgtcaattcc gtgtccaact atcattctca tcaaaaggag ttgagattcc ccaactccat
     5401 ccttttcact tattttgtca aggtaacata aatctcttct accaaggcct ctgtattttc
     5461 ccaacctagg caagggtcag taatagagca accaaagatc tctggttggt tttgacgacc
     5521 atctgctagg taagattcaa tcataaatcc tcgaaccgtc tttttaattt tctcattcca
     5581 atcacgattc tgcaaggtct ggcgaacaat tcgaatctgc tccatatatt gcttgcctga
     5641 gttatcatgg ttggtgtcaa tgaggataaa aggattttca agtcccatgg tttcatagcg
     5701 ttcaatggct tggagtagat tttcatagta gtaattcggc atataattgc catactcgtt
     5761 gactgctcca cggaggataa catgggccaa aggattacct gatgtctcaa cttcctgccc
     5821 atgataaagg aaggtttgct tgttttgagc agcatagatg gcgttaaaca taacacccaa
     5881 atttcctgag gttggatttt tcatccctac tggtgcatca atcccagaag ccacaaagcg
     5941 gtgctcttgg tcttccacag aacgagctcc aacggcatgg tagctgacca agtcatccac
     6001 caagatcaga tttgacggat aaagcatctc atctgccgtt gtcaaaccag tctctgtaat
     6061 cacgcggtag tgcaactggc gcacagcctg caagccatta atcaggcttg gagccttaga
     6121 agtatctggc tggtgaacta atcctttata gccgtctcca ttggtacgag gcttagcagt
     6181 atacacgcgc atgaccatga aaatcttatc cgctaccttc ttttgcaagg cagataaacg
     6241 gcgagcatat tccaagaccg cctcttcatt atcagaagag caaggaccaa tcaccaagag
     6301 aatacggtca tcttcccctg aaataatatc tgccaattcc ctgtcacggc tttccttgag
     6361 tctcaaggct tccgcagaca attgggtttc agccttgatg acttccatat cgatttcttg
     6421 acctttttca ataaatgcca tcttattctc ctaacgtttt gtaaatttct ctgacaagag
     6481 cttctgtgtt atcccaaccc aggcaagggt ctgtgataga cttaccaaat aattctggct
     6541 cattttgtcg accatcttcc agataagact caatcataaa accacgaacg aactgcttaa
     6601 ttttttcatt ccaagcacgg ttaatcaagg tctggcggac aattcggatc tgttcaatat
     6661 actgcttacc agaattgtca tgattggtat caatgatgat aaaaggattt tccaagccca
     6721 ttttctcata ctgggcaatg gtatcaatta aattgtcata atagtagttg ggaatatttt
     6781 ttccatactc attaagagca ccacgaagaa tagcgtgtga aagcgggttc ccagttgttt
     6841 ctacttcttt tcctaagaaa aggaaacttt gtttgttttg agcagcataa atcccattaa
     6901 acatgacatt gagatttcca gaggttggat ttttaaaacc agtagaaaat cctgccccac
     6961 ttgccacaaa gcggtgttgc tggtcttcaa ctgaacgggc accaactgcc atgtaagaaa
     7021 tcaaatcatc tacaagcgga aggttttcag gataaagcat ttcatcagca gttgtcatcc
     7081 ctgtttctgt gatgacacga tagtgaagat ggcgaacggc tttgattcca ttgataagac
     7141 taggcgcttc tgtcgcgtta ggctggtgaa tcaagccctt atagccatct ccgttggtac
     7201 ggggtttggc agtataaaca cgcataacca taaagatacg atctgccact tcttcttgta
     7261 ggactgccaa acgcttagcg tattcaagga cagcttcttc gttgtcagat gagcatggcc
     7321 cgattaccaa gagaattcgc tggtcttctc cacgtataat ggcttctagc tcttgatctc
     7381 gctgtgattt cctctccaaa gcctgacctt ctaattttga caaggcacga acttcttcta
     7441 tatttatttt agagcttttt gctgtaaata ccataactca tctccttata aagcaaacgg
     7501 atacccagta aaaatttact tttcacaaga tatccgcctc taaactatct cattttattg
     7561 tcttttaccg tgacagtttt taaatttctt accagaacca catgggcaaa gttcattgcg
     7621 tccaatctgg ctcaaatcca aatcttctgg catacttgct tggtgagcag cgatattgcg
     7681 agtcgctgtt gtactgatat gacgttctgc ctgtggtctt tcttgttcat gaatttgtgc
     7741 tttcatcatc aagcgtgtca catcaaactc aatcgaacca atcatatcat taaacatacg
     7801 gaaaccttct gcctgatact caacaacagg gttgttctga gcatagccac gaagtccaac
     7861 cgcgttacgc aattgatcaa gggcatcgat atgatctgtc cacttgttat ccaccactcg
     7921 tagaatcaaa actttttgga attctttaac tgcttcttca tcgcgtagtt ttgaaacctg
     7981 actatcgtaa accttcaagg cacgttggaa aagctcttcc ttgatggcct tatcagacaa
     8041 gcctgacaag tcttccatcg taatagaatc ttcaggaagc aagttatact tagcgaagtt
     8101 caaaattgcc tctagtttct catcttgttt agcacgcgca tgaccgtcaa cgacacgacc
     8161 aatcgtgcgt ttgatcattg cctgaatttc aggtgccaag tcacggtctg cagtaatgac
     8221 atcataacgt tgagtataga taatctcacg ttgttcacgc atgacatcgt cgtattgaag
     8281 gacttgttta cgggtatcgt agttatttcc ttcgacacgt ttctgagctg cttcaacctg
     8341 acgcgtcaac atgcgagact caatcgcctc ttcagacatg ttcaagcgtt caaagattcc
     8401 cttcaagcgt tcagaaccaa aacgtttcat caaatcatct tcaagagata ggtagaattg
     8461 tgactcacct ggatctcctt gacgacctga acgtccacga agctggttat cgatacgacg
     8521 actttcatga cgttctgtac caataacaca aagtcctcca agttcacgaa caccttcacc
     8581 aagcttgatg tcggtaccac gacccgccat gttggttgcg atggtaacgg caccacgttg
     8641 accagcattc atgatgattt gggcttctct atagtggttt ttggcattca agacttcgtg
     8701 aggaacacca gctgcaacca atttcttaga aatgtagtca ctagtttcaa ccgctactgt
     8761 accaaccaag acaggttgac ccttttggta acgagcctta acgtcttcga caaccgcttt
     8821 aaacttagat tcgatacttg cataaagaag gtctgagtgg tcaatacgtt gaacaggacg
     8881 gtttgttggg attggaataa cacgaatgtt gtagatttca cggaattctt cttcctcagt
     8941 cttacctgta cccgtcatac cagacaattt cttgtacata cggaaaaggt tttggtacgt
     9001 gattgaggca gatgtcttgg tttcatcctg gattggcaca ccttctttgg cttcaatagc
     9061 ttggtgcaat ccatcagaat aacgacgacc ttccatggta cgacctgtaa attggtcgac
     9121 aatcaagatt tcttgctctt cgctcaccac atagtcaata tcgagaagca tgatgtagtt
     9181 ggcacgaagg gcgttatcga taaagtgggt caaagccacg ttttcgatgt catagaggtt
     9241 ttcaagtttg aagtagcttt cagccctgtc aatccctgaa tcagacaaac caatagtctt
     9301 agactgcaca tcgatgatgt agtcatcttt gttcaaagat tttacatagt ggtctgccat
     9361 gtgatacaac tgactggttt caaccgcatt ggcacctgat acaatcaaag gtgtacgagc
     9421 ctcgtcaatc aagatagagt caacctcatc gaccaaggca tagttaagcg gacgttgtac
     9481 catgttttca gcgcgaacga ccatgttgtc acgaaggtag tcaaatccga tttctgagtt
     9541 agttgagtaa gtaatatcac actcataggc ttcttttttc tccattggag atttggtagc
     9601 caagttaatc cctactgaca aaccaagcca agagtacaat tcacccatct cagtcgcgtc
     9661 acgttctgac aggtattcat taaccgtaac tacgtgaacc cctttacctg aaagggcatt
     9721 gaggtatacc ggcatggtcg cagtcaaggt tttcccttcc cctgtacgca tctctggcac
     9781 gtcaccatgg tgaagaacaa tcccccccat gacctgaacc ttataaggga agagacctag
     9841 gacacgtttg gcaccttcac ggacaaccgc aaatgcttcg taaagcaatg aatccagtga
     9901 ttctccattt tgataacgtt ccttaaattc aactgttttt gcttttagtt ggtcgtcagt
     9961 caaagcagcc atttggtctt cgtatttgaa aaccttgtca gccatctttt ccagacgacg
    10021 gatttctcct ttatcatttt cgataattgt ttttaaaata ttagccatgt ttttccttac
    10081 tttaaattcc gaatatttta gaatgttcct ttaattttag cacaattact gattattttc
    10141 aaggaagaat ccccattttg aaaaggaaaa agaggttagt ttccaagcta acctctctga
    10201 cttttatgat actttaattg ccaagaatcg gcaaaatagc aaataggata aataagttaa
    10261 tccaaagaga aagacagcag atcaatccaa aaacaaagag actgactttc ttggacagca
    10321 aggccatcaa aatggacaga atgccaaaaa ctagcaagac tttctgtatg ctgaagaggt
    10381 caatcttccc ccccagaatc ggactgcccc aaggaagaaa gaagaaagca atccagatca
    10441 acagaactaa accaatatag accttagaat agcgtgtaat aaatgatttt agattcaaca
    10501 tcctatagct ccaatcgttt caaaataaac tctgatagca tccgcaaccc ataaggcact
    10561 ttctggtatc caacgtctgt taacttttat aaaatcgact aactgacgat tacactcaca
    10621 attagctcca ataccagctc cccacttgta acatctatca tgattttggc aaccttgatc
    10681 caaaacgtct accacaggta aagtaaatcc ttccccgttg taaccaggac cacagtaatt
    10741 cccgtgaaca ggcaatcctg ccttaaaata tttagcaggt gtaaacgtat ttgaactata
    10801 gtcttcgctt attgtctcta ccaataaacc catgtcaatt acatctttcg cttgtttatc
    10861 ttgaaccgct ttatcataat caaaataaat cctatcttta tcttttacaa gataactctt
    10921 caacaattct ccgttacgaa aacttctatc gctaacttcc aaagagttta agttatcatg
    10981 tgaattagag tctgcaaaaa cattttttcc agcaaataaa agtaaaaagg cagataaagc
    11041 aactaaacaa attttaacga tagttttcat gactactcct cctaataaac ataagttata
    11101 agctaaatac acaaacaata tttttaccaa aagaaagtta atttttggta aatgtactaa
    11161 atacacataa acttaaagct tgtcaaatga gtttaagaaa tacatgtttt atattattct
    11221 aacagatgat atttcatatg ttctcctcct tacctataag ctataaaata tttaagtttg
    11281 gctataataa aactacaaaa aataagtatg tcaaacttaa ctaaagaata taaataacac
    11341 atcaattagt cactcccaaa accatatatc aaaccatggt attaaaggct cccaatcatt
    11401 acaatatata acaaaattaa gtgaatcttc tatttccatg acttttccct cctttttgat
    11461 ataataatac cacctttttc tacgtttttt ataaatgtag aaaatattca catttaccta
    11521 ggaggaacaa tatgagatgg gattatggac agatttttaa agaaattcga aagtcaaaag
    11581 gattgaccca acaagatgta tgtggacaag tcatacatcg gacaactcta acaaatattg
    11641 aacacggtaa agttattccc agttttgaaa acatggtatt tcttcttgaa caaattgata
    11701 tgagcttggc agaattcaag tatatatgga acgaatacca tcctagtaaa aggcgagata
    11761 ttattgtaga gagccaaaat ccgtctactt ttcaagatac tagaaaaatg gttgaactca
    11821 ctgagaaatg tcaaaaatat cttaagacac atcacgatgt tcctattcaa aatatctatc
    11881 gtcatacaaa aattgtcaca gagttacgaa ctaaaggatt caaaaacaac cacgtcttga
    11941 aagatttgtc tgaagaaatt tgggactatc ttgaacctat ggatacatgg tacattagtg
    12001 atttgaaatt gcttggaacc attctctttt tctttccttc tgaaaatctt ccccttctta
    12061 ttgatagaat tatgaaaacc atcgagaaat ataaatactt ccgagaaaca aaagtatttt
    12121 tatcatcttt tttagccaat ctctccactg tatattttca acatcattta ttcaaagaat
    12181 gtgaaacaat caccctacaa cttttggtat tagcagaaga attaaaaata tacgatattc
    12241 ttggattctc tcaagtacgc ttgggaatac tacaacataa ctccgatttg attgataaag
    12301 gaataacttt attacgacta accaaagaag aggcattagt tgaaatactc gaaaaagaaa
    12361 ttaatgattt ttcaaaccta taatttgtaa taactctcat cattttatta tagtagattg
    12421 taatagaata tgaacgaatc aattagggga tctaaagcat tttataccaa tgttttataa
    12481 gttgtattgt attattccat attcaatcca ctatacaaga tgaatatttc tctcaagttt
    12541 cataatcaaa ataaaaatga ctgtatctat agctccataa acaaatcata gatacagtca
    12601 ttttttagtt cctacacctt cctttatgca cacctttaga cttccctagt tcccgtctca
    12661 agtcaagcat ttttttgaaa aagacatagg ctaaccaatc actagcaaaa gcgataagta
    12721 gtaataatag ccaaataccc cataacttga tatctgtcaa atttctcaag acgatattga
    12781 aaaacagaac tgaaaaaact gtccaagcaa ggctaaaaag agcatagagg gtgatgtaaa
    12841 tccagtaaaa atagtaaaaa attgggaaaa atttactttc tctattatcc ttgtcaatcc
    12901 agctgaaaaa gtaaaaacag ggtaataaga ttatcatttt aaacaagtgt tccatcacaa
    12961 acctcctctt ttaaattgtt ttctttagtt tcgttctatt aaatgttatt accaatataa
    13021 accttggaat agcgtgtaat aaatgatttt agaggtacca taaggccacc tcctacaaat
    13081 agaaaccgat ataaatcaat gccttccacc cttagacttc cctagttcct gtctcaagcg
    13141 aaacatttct ttgaaacagg aataagttaa ccaattcata ccaatagcta gcagaataaa
    13201 aagaaaccaa atgccccata acttgatatc tgtcacattt ctcaagacgg tattgaaaaa
    13261 cagaactgaa acaactgtcc aagcaaggct aaaaagagaa tagaagggga tgtaaaacca
    13321 gtaaaaataa taaaaaattg gaaaaaactt actatttctg ttggccttct caatccagtt
    13381 atcaaaataa aagtacggtg ctaaaagtaa gaatttaaac aaatgttcca tcaccgacat
    13441 caccctcttt cttttgatag cgttttctat tattttatta tatcaaaaaa atccggaact
    13501 gtcattccag attctacttt tttatttgcg ttttcttgcg atgagatgaa tcggtgttcc
    13561 ctcaaaaaca aaggccttgc ggatttgatt ttccaagaaa cgcaggtaag aaaagtgcat
    13621 gagttcttct tcattgacaa agatgacaaa ggttggtggt ttggttgcca cttgggtcgc
    13681 atagaaaatc ttgagacgtt ttcctttgtc tgtcggtgtt gggttgatgg caatggcatc
    13741 catgatgaca tcgttcaaga cagctgatgg aatacgtgta ttttgacttt cgctgatttg
    13801 cttaatcatc tcaggaagtt tgtggagacg ttgcttggtt aaagctgata caaagataat
    13861 cggtgcgtaa ggcaggtatt ggaactgctc acggatatct tcttcccagt ttttcatagt
    13921 gtggttatct ttttcaagcg tatcccactt gttgaccacg ataatcatcc ctttaccagc
    13981 ttcatgggca aatcctgcga tacgcttgtc gtactcacga atgccttctt ccgcattgat
    14041 gaccatcaag accacatctg aacggtcaat agcacgcatg gcacgcataa cagagtattt
    14101 ctcagtattt tcataaacct taccagactt acgcatacca gccgtatcaa tcatggtaaa
    14161 ctcttgacca tctgtatctg taaagtgggt atcaatggca tcacgagttg ttccagcaac
    14221 aggactagca ataacacggt cttctcccaa gatagcattg atcaagcttg attttccaac
    14281 gttaggacga ccaatcaagc taaacttaat gacatctgga ttttcttcct catattcatt
    14341 tggaagattt tctacgatcg catctagcac atcccctgta ccgattccat ggacagatga
    14401 gataggcaat ggttcaccca aaccgagagc atagaaatca tatatatcat ttctcatctc
    14461 agggttgtcc accttgttga ctgcgaggat aactggtttg tgggtcttat aaagcttacg
    14521 agctacgtat tcgtctgcat cagtaattcc ttccttacca gacacgacaa aaacgataac
    14581 atctgcttct tccatggcaa tttctgcctg gtgcttgatt tgttccatga aaggagcatc
    14641 gacatcatca attcctcctg tatcaatcat gctaaaagaa cgattgagcc actcacccgt
    14701 tgcataaata cggtcacgtg tcactccttc gacatcttct acaatggaga ttcgctcacc
    14761 agcgatccga ttaaataggg ttgatttccc aacattggga cgtcctacaa tggcaatagt
    14821 tggtagggcc ataatttctc actttctaca ataatttctt ttgttcaaga ttttttctag
    14881 ttgagcttgg ttcagcttga ccaaactgtt ctgctaggcg ctgactccag cttgtggtcg
    14941 cacgcgcccc agcatagtca gcctgaacac ggtcataagc ttggattgcc tcagttgact
    15001 gttcttggta ttcttcctca aagacaacat tctctagtgg cagtctcggt ttcatatcat
    15061 gatgttgatt tggcacaccc agtgccatcc caaagacaga ataggtgtag tcaggtaggt
    15121 taaagagctc tgccacttct tcagacttgt atcgaaccaa accgataatc acaccaccat
    15181 agcccaagct ttcagctgcc aacaaggcgt tttgtccagc aagagctgca tcgaccgaac
    15241 taatcaagag accttccaca ccttggggtt ggaaggtgtc ggtatgaagt cgggctccct
    15301 tttctgctcg gttcaaatct ccgacaaaga gaaggaaaac agcagactgg cgaatggctt
    15361 cttgaggtac caatttatac aaggcatctt tcttctcttg acttcgtacc acaatcacag
    15421 agtaggattg gaaattcttc caagatgatg ccatctgggc tgctgtcaaa atctcattta
    15481 agtctacttg gggaatttct tgctctttaa acctgcgcac tgaagtatga gccttcatca
    15541 atttaatggt ttctgtcatc gacggtttac tccttctaaa cgagtctcct cagccaaata
    15601 acggatgcgt tccatgacgc gtctggcttc ccaggtttcg tcatttccat ttttcccttt
    15661 agcaaaatgc ttctccaaat cttcaaagtt gaagttggat gtgaaaaagg tcggtaaatt
    15721 ttcctgcatc cgatattgga gaatgacctg caggatttcg tcacgcaccc aaacggttga
    15781 ttgctcggcg ccaatatcat ctaaaatcag gacctcagac agcttaatct catccaccaa
    15841 ggtcttaaca ttgccatcac tgatagcatt tttgacatca atgacaaagc taggatagtg
    15901 gaggagagtt gatgaaacac cacgtttttc tgataaatca tgagctaagg ccgccaccat
    15961 gaaactttta cccacaccaa agtctccata taagtaaaga ccttttcgaa tagctggata
    16021 ttgctccacg aaggctagta gcttttcaaa aactggtaag cgccccaaat catccaagtc
    16081 aacttgagcc aaactagctt tcttgagact ggctggtaga ttgattaact tgagacggtt
    16141 cttaatagcc gcttcttttt cagccgcgat tagctcagga gtttcttcat atgaaacatc
    16201 tgcatagcca tgattcttaa ccaaaatcgg cttgtagcct ttggcaatat aatccgtatc
    16261 cccacggaga aacttgtcac gctcggtgat gtactgatta aacttggaga tactgcgatt
    16321 taattcctct ggagtcaagg attcttgctg gataaaagcc gcaacatcag ggtccttcat
    16381 gattttctgg accaaatctt gataataaaa acggctgggt tgacgtttga gtacgtctcc
    16441 gacactttcc atctaatctc ctcctttttc taatcgagct aatagttctt gcttcttacg
    16501 ttctagttcc agacgagttt cctcgctggt ttcattctta tattcaggat tactccattt
    16561 aggaacattg gtttttactg gggcagtctg attctgtttt tgtatttttg ctttctgtcc
    16621 tcgctcacgg atgcgcaaga ctgccttttc tgccgaatga atcttttgat aggcatagtc
    16681 attggctacc ttcatggcat atttctcatt gatatttgcc gaatcgacct tattaaaggt
    16741 caataaaaga atgatattga tgacttcgtc cagcaagccc aagccagcca tctgttgcaa
    16801 gagttctctt tctgtttggg taatggttcc cttgcgtgtt tgcttgattt ctgccaagaa
    16861 ctgcagggca gttttacttt tggcttcttt gataatggtt gtttccttaa gactaaagtc
    16921 agaggaaact ggtttttgag caattttttc acgcatgcgt ttggttgaaa taacctgaga
    16981 aacagctgtt gacttggcca attgataggt ttcaaaccaa gtccatttct tctcctcggc
    17041 aatagcaaag aggtttaaga catcggactg ctcatccgca aaacgaagtc catctcgagc
    17101 catcagctgg cgaaaatggt ccaagtcaaa atcgttggcc actttcttct tgagaccaag
    17161 gtcttcttga ctgcctagtt ctgccaattc tggaaagact tgattgagtg agacaggtat
    17221 ttcttcacca tcagcacttt caactttcaa atcctccaca gctacatcgc caatcttttt
    17281 ctctaagagt ctgcgataaa caggatgctc caagaagtct tgactagata gaggagcatg
    17341 gaggactagc tgataaacat cccccttttg atagagggtc aagagattaa aagcagataa
    17401 gattttcaat gattttatca gtctatccat cccaaagtta agatggttga gaatgcttga
    17461 aaaaagatat tcctttctac cattatccca aaaactgatt gtataaagat aaaggctcag
    17521 tgcctcctga ccgataatcg ggaggtagca ctgtaccaga gatgaggtat cttgcgacac
    17581 ccgattattc tttagataag aaaaacggtc aattggcttc atttatcttt cctttttctt
    17641 tttagaggac tgggtgattt gttggagcaa gctctctaac tcactgacat ccttaaaact
    17701 acgatagaca ctagcaaaac gtacataggt aatctcgtcc aattcagcca actcctccat
    17761 gacgagtgaa ccaatgtcct cactttgaat ttcattttca tttcgaccac ggagtttctg
    17821 ttcgatacga ttgactacca tgttgatttc atcacttgac acaggacgtt tctgggctga
    17881 gcggataatc ccattaaaga ttttatctct ggagaattgt tcccgtgtgc catctttttt
    17941 aacaaccact aaggttcttt cttctactcg ttcgtaggtt gtaaaacggt gttggcattc
    18001 gtcgcactca cgtcttctac gaatggtgtt cccttcttct gcttggcgac tatcgataac
    18061 acttgacttg gtagccccac attttggaca acgcatcctt tccctcctta tcgttttctt
    18121 ttcattatac cattttttaa gcgattccca aaacaattct tctttttgct tgacaagttt
    18181 tttgttttgt tgtattattt aattaagaca aaagggtaaa agaaaggaga ctaagatgtc
    18241 ctggacattt gacaacaaaa aacccatcta tttacagatt atggagaaaa tcaagcttca
    18301 gattgtttcc catacactgg aacccaatca acaacttcca accgtgaggg agctagctag
    18361 cgaggctggt gtcaatccca ataccatcca aagagcctta tcagaccttg aacgagaagg
    18421 atttgtctac agcaagcgaa caactggacg atttgtgact aaggataagg agctaatcgc
    18481 tcagtcacgc aaacaattat cagaagaaga attggaacac ttcgtttcct ccatgaccca
    18541 ttttggctat gaaaaagaag aactaccagg cgtagtcagt gattatatta aaggagttta
    18601 agcctatgtc attactagca tttgaaaatg tatccaaatc atatggagca acaccagccc
    18661 ttgaaaatgt ttctcttgac attccagctg gaaaaattgt cggccttctt gggccaaacg
    18721 gctcaggaaa aacaaccctg attaaactaa ttaatggcct cttacaacca gatcaaggac
    18781 gtgtcctcat caacgacatg gacccaagcc cagcaaccaa ggccgttgta gcttatttgc
    18841 ctgatacgac ctatctcaat gagcaaatga aggtcaaaga agccctaacc tacttcaaga
    18901 ccttctataa agatttcaat cttgaacgcg cccatcatct acttgcagac ctgggcattg
    18961 atgaaaatag tcgtctcaag aaactatcaa aaggaaacaa agaaaaggtt caactgattt
    19021 tggttatgag ccgtgatgct cgtctctatg ttttggacga acccattggt ggggtggatc
    19081 cagcagcccg tgcttatatc ctcaatacca ttatcaacaa ctactcacca acttctaccg
    19141 ttttgatttc tacccacttg atttctgata tcgagccaat cttggatgaa attgtcttcc
    19201 taaaagacgg aaaagtcgtc cgtcaaggaa atgtagatga tattcgctac gagtcaggtg
    19261 aatccattga ccaactcttc cgtcaggaat ttaaggccta agcaaaggag attatttatg
    19321 ttttggaatt tagttcgcta cgaatttaaa aatgttaaca agtggtattt agccctctac
    19381 gcagccgtgc tagtcctttc tgccctcatc ggaatacaga cacaaggctt taaaaatcta
    19441 ccttaccaag aaagtcaggc tactatgcta ctttttctag ccacagtctt tggtggcttg
    19501 atgcttacac ttgcgatttc aaccattttc ttgattatta aacgcttcaa aggtagtgtc
    19561 tacgaccgac aaggctatct gactttgacc ttgccagttt ctgaacacca tatcatcaca
    19621 gccaaactaa tcggtgcctt tatctggtca ttgattagca ccgctgtatt ggctctaagt
    19681 gctgttatta ttctggcttt aacagctcca gaatggattc ctctttctta tgtgattaca
    19741 tttgtagaaa cacatctccc tcagatcttt cttacaggta tatccttcct actaaatacc
    19801 atttcaggaa tcctctgcat ctacctggct atttccattg gacagctttt caatgaatac
    19861 cgtacagcac tcgctgttgc agcctacatt ggtatccaaa tcgtcattgg atttattgaa
    19921 cttttcttca atcttagttc taatttctat gtcaattcac tggtaggact caatgaccat
    19981 ttctatatgg gagcaggtat agccattgtt aaagaactca tattcatagc tatcttttat
    20041 ctcggaacct actacatctt gagaaataag gttaatttgc tttaaataat ttttacctag
    20101 atatgtaaca tactcataga acaaaagaaa ccaggcaaaa agtctttaaa attagaaaac
    20161 gcatagtatc aagtgttaaa aatccttgat attatgcgtt ttttgtgagc tgacttattt
    20221 cctttcacta tatcgcaaaa tgaaataaga acggaacgat gagattttgg aattcaaatc
    20281 aatttataag aatgttttag aagtaatatt atcctattcc agattcagtt cactatacaa
    20341 ttgagttttc aagcaacctg tttacataat gtgtacataa ttaggttcgt gattccaccc
    20401 ttttcacctt taaaaacctc gctttcgcaa ggctcttcta tttataagat aaggcacgtt
    20461 taaaggtttt ccaaatccct aaatcatccg tttgaagaac gagactagca tacatgcgtc
    20521 cgataaatcc tgttgctacc accgcaaaaa tcactgtaat agcaagtgaa atccatgctt
    20581 ctgctccccc cgcatagtca ttaatcgttc gaaacggcat aaagaaggtc gaaataaagg
    20641 gaatataaga accaatcttc aagaggagat tgtcaccagc tgcacctaga gctgtcactc
    20701 caaaaaaacc acccataatc aaaatcatca aaggcgacaa ggctttccct gagtcctcag
    20761 gacgagaaac catagatcct aggaaggctg ccaagactac gtacatgaaa agactgatca
    20821 aaataaagag caaggtattc agtgagatag catctcccaa gtgaaccaaa ataccagact
    20881 gagccaagaa tggcaaacct ttaaagagca aaacggcagc cagaccacct acaacataga
    20941 tcccaatatg cgttaaaatc actagaaaca gagccatcat ccgcgcatag aaatagtgac
    21001 ttgcccttat gctagaaaaa acgacttcca taattttggt gcctttttca ctggcaactt
    21061 cctgagctgt tacacccgca taggtaatca gaatcatata aagaaagaat cctaaggcac
    21121 ctgctgcaat tgtttgaata aactttttat tttccttgac ttcatcaatc ttttctgtga
    21181 attgaattgt ctgcgctaag cgtttttcct gctcttgaga caaggaagca gttgaacgat
    21241 taagctgatt ttgcagttca ttgagtatac ctgtaacctc aaatttaatt ccattttcaa
    21301 gcgatgtttc gccatgataa actgccttta gaacactatc ttcttgatca atggtcaaat
    21361 aaccttttaa tttttcttct ttaattgctt ctttggcact tgcttcatct ttatagtcga
    21421 agttaacacc atttacattc ttcagtcctt ctgctacaga tggcactgtt gtcactactg
    21481 ccactttatt atttttagcc atagaagaac cttggagatg cccaattcct acagagattc
    21541 ctaaaaagag gaacggcgaa atcaccataa agaagaaact ccatgactcg acatgtcgaa
    21601 gataggtttc cttgattaca acccacatat ttctcatact tccactcctg attctagttt
    21661 aaagatttca tcgatagttg gcgcttgttg gtcaaatgtt gcgatatatt gaccttgagt
    21721 caagattggg aagagttccc ttccagcgct ctcatcctcc aaaatcaatt tccaactgcc
    21781 ttgtttggtc aagctcacct gtttgacatg aggaagattt tccaattctt ccttgcttcg
    21841 ttcacttgaa acaaagagac gcgttttccc gtattgattg cggacatcct gaactggtcc
    21901 gtgcaagacc acacggccat ctcggatcat cagaatatcg tcacaaagtt cctcaacatt
    21961 ggtcatgaca tggtcagaaa agataatggt tgctccgcgc tctttttcct gaaaaatgac
    22021 ttgtttgagc aattctgtat taactgggtc caatccacta aaaggctcat ccaagataat
    22081 caggtctggt tcatgaatca gagtaataat gagctgaatc ttctgctgat ttccttttga
    22141 cagactcttg attttatctg tcagctttcc tttcacttcc aacctcttca tccattgagg
    22201 gagtttttct ttgacttctt tggcatccat gccttttaga gtcgccaagt agcgaacttg
    22261 ttcaagaact gtcaatttag gcatgagact gcgttcttca ggcagataac caatccgagc
    22321 ataggtctcc tgacgaatat cctgaccatc cagaccgatt tctccctgat attctaggaa
    22381 tttcaaaata ctatggaaaa tcgttgtttt tccagcacca ttttttccga ctagtcccaa
    22441 aatacgacct ggtcgcgctt gaaagtcaat accaaacaaa acttgcttgg atccaaaact
    22501 tttctctaga cttcttactt ctagcatctt tcacctccga aatttcttgc actcattata
    22561 ctcctttttg atagccttta caatgttttt tgtccatttt tagaagacta ttgctgtgta
    22621 aaatatggcc tggagcactt ttatactcaa tgaaaagcaa agagcaaact agaaagctag
    22681 ccgtaggctg ctcaaagtac agctttgagg ttgcagataa aactgacgaa gtcagctcaa
    22741 aacactgttt tgaggttgtg gatagaactg acgaagtcag taactatatc tacggcaagg
    22801 cgaagctgac gtggtttgaa gagattttcg aagagtatta gtgataaatc cattatacag
    22861 tagcaaactt aatttatacc ttccgctcct caactgtcta tttttaatcc tgaattgtta
    22921 tttgagtaac tcctttttcc tcataaagtt ttcttcctct aaaacttctg gaaaaaggcg
    22981 aatagtttca gacaacattt ttataagaaa caagttcatc tgtcatttca agaaggagta
    23041 atcctttatc tactaatgga cggaacagaa ttcaaccgct tgtcccatat gttttctaag
    23101 gattatatag taaaatgaaa taaaaacagg acaaattgat caggacagtc aaatcgattt
    23161 ctaacaatgt tttagaagta gatgcgtact attctagttt caatctatta tatctattat
    23221 gcacaccact ataggatcta ataaaaatca caacaagttc attcatagat ggttacctca
    23281 gggaactaag aaaacgacta caaaggaagt cgcattcatc gaaaagtgga ttaacaacta
    23341 tcctaaaaaa tgcttgaact acaagtcccc cagagaagac ttctggatga ctaacttgaa
    23401 cttgaaattt agcaataatt aattcaccat ctaactatat ttagtaatta tttcagaact
    23461 gattaatatt aaaattaact aacaattcaa aggattcata ctagccataa attacgtcca
    23521 tcagagagag actcttacta cttttagatt ttagtctttc tagcttcaga atacatctaa
    23581 actttaggga aaatgactat tcgaaagcgc gaatgcctca aaattatctc agataagcta
    23641 ttcgaaactt agaatgcttt taaatttatg gaattgcgat tattcgaaac ctagaatgca
    23701 tataaccttt agttgacaga cctattctaa gtctcgaagg gctatttact ttctattcct
    23761 tatcaaaaaa gactcattcc ccctttctcc tccaaaatat ggtatagtag aaatatacta
    23821 tctatgagga gtttacatgt cacaggataa acaaatgaaa gctgtttctc cccttctgca
    23881 gcgagttatc aatatctcat cgattgtcgg tggggttggg agtttgattt tctgtatttg
    23941 ggcttatcag gctgggattt tacaatccaa ggaaaccctc tctgccttta tccagcaggc
    24001 aggcatctgg ggtccacctc tctttatctt tttacagatt ttacagactg tcgtccctat
    24061 cattccaggg gccttgacct cggtggctgg ggtctttatc tacgggcaca tcatcgggac
    24121 tatctacaac tatatcggca tcgtgattgg ctgtgccatt atcttttatc tagtgcgcct
    24181 atacggagct gcctttgtcc agtctgtcgt cagcaagcgc acctacgaca agtacatcgg
    24241 ctggctagat aagggcaatc gttttgaccg cttctttatt tttatgatga tttggcccat
    24301 tagcccagct gactttctct gtatgctggc tgccctgacc aagatgagtt tcaagcgcta
    24361 catgaccatc atcattctga ccaaaccctt taccctcgtg gtttatacct acggtctgac
    24421 ctatattatt gactttttct ggcaaatgct ttgacacgta aaaaatccgt ttggtttccc
    24481 aagtggattt ttaaagcgta gattaactat agcttgatac taaatatact ttggtatgga
    24541 aatcatgcat atttttcgat agtgaggcga ggacttacct agcctttccg ccgtgataga
    24601 aacacctgaa atctaatggt ttcaggtatt cggaaacttt gagacactag gctcaaagtt
    24661 taggtatgga atttcgaaga aagtcgctac cgtccgtaat cacttaagga aaggctcaaa
    24721 aatattgttt tcaaccacaa aatccgtttg gtttcccaag cggattttgt gctttatttt
    24781 gaaacttctt ttgcaagaac aaagttccca agtgtggcag aaccatttcc tgcgactgct
    24841 ggcgtcacga tatagtcacg cacatctggt actggtaggt aaccattaag aagagatgta
    24901 aatttctcac ggacacggtc cagcatatgt tgttgagcca tgacccctcc accaaagaca
    24961 atcacgtctg ggcggaaagt cactgtcgca ttaaccgcag cttgagcgat atagtaggct
    25021 tgaacatccc aaacagggtt gttgagttca atagtttccc cacgtacacc tgtacgagct
    25081 tccaaacttg gaccagctgc ataaccttct agacatccct tatggaaagg acaaacaccc
    25141 ttaaactctt tttcaatatc cattgggtgt ctagcaacat aataatgacc catttcaggg
    25201 tgacccacac caccgataaa ctcaccacgt tggatgacgc ctgcaccgat acctgtaccg
    25261 attgtgtagt aaaccaagtt ttcgatacga ccaccagcat tgttacgggc aaccacttca
    25321 ccgtaagcag agctgtttac gtctgttgtg aagtacattg gcacgtttag ggcgcgacga
    25381 agggcaccaa gcaagtccac atttgcccag tttggttttg gagtcgtcgt gataaagcca
    25441 taagtttttg agtttttgtc aatatcaatc ggcccaaatg aaccaactgc aagaccagca
    25501 aggttatcga attttgagaa gaactcaatg gttttatcga ttgtttcgat tggagttgtt
    25561 gttggaaatt gtgttttttc tacaacgtta aagttttcat caccgacagc acagacaaac
    25621 tttgtaccgc ccgcttccaa gcttccatat aattttgtca tgataaacct cttgttttta
    25681 ttttctttat tatagcatac ttcgaaagtc taaatgtctc tattttttag attttcctct
    25741 gtaaatctta ctatctaata aaaacgaaca aacatgtcat ttgttcgttt tcacattaga
    25801 gaggattgat tagattttca cttcgatcac agcatccccc ttagcaactg aacctgttgc
    25861 gactggagct actgaagcgt agtcacctgt atttgtaacg ataaccattg ttgtatcatc
    25921 aagtccagct gcagcgattt tgtttgagtc aaatgttcca agaacatcgc cagctttcac
    25981 cttattacct tgagcaactt ttacttcaaa accgtcaccg ttcatagata cagtgtcaat
    26041 accaacgtga atcaaaactt cagcaccatt tcttgttttc aaaccaaaag cgtgccctgt
    26101 tggaaaggca attgaaactt cagcatcagc tggtgcatag accacgcctt ggcttggttt
    26161 cacagcgata ccttgtccca tagctccact tgagaagact gggtcattga catcagcaag
    26221 agcgacaaca tcaccgacga taggagttac aagtgtttca ttttgaagag ctgctggcgc
    26281 aacttcttct ttttcttcag ccacttcagc ttgttttgca gctgcagttg cgtctacttc
    26341 atcttcgtaa ccaaacatgt aagtaagagc aaaaccaagg gcaaatgata cagctaccat
    26401 aagaaggtat tgtggaagtt gtccgttacc aacataaagc attgtaccag ggatgatggt
    26461 gataccatta ccagtaccag caagtccaag gatagaagcc aatccaccac cgattgcacc
    26521 agcaatcaat gaaaggaaga atggtttacg gaagcgcaag ttcaccccga agatagcagg
    26581 ctctgtaata cctaggaagg cagaaagagc agccgggaaa gcaagtgttt tcagttttgg
    26641 attttttgtt ttaacaccaa ccgcaacagt agcagcacct tgagctgtca tagcagctgt
    26701 gatgatagcg ttgaatgggt tagcatggtc agcagcaagt aattgcactt caagcaagtt
    26761 gaagatgtgg tgcacacctg acacgacgat caattggtga accccaccaa tcaagaaacc
    26821 accaagacca aatggcatgc taagaatcgc ttttgtagca ataaggatgt agttttcaac
    26881 aacgtggaaa actggtccaa tgacaaagag tccaaggata gacatgacca aaagtgtcac
    26941 gaatggtgtt accaagaggt caatgacatc tggaacaacc ttgcggacag ctttttcaaa
    27001 tttagctccg acaaccccga tgatgaaggc tggaagaacg gaaccttgca aaccaacaac
    27061 agggatgaaa ccaaaaaagt tcatcgctgt tacttcacca ccttgagcaa ctgcccaagc
    27121 gtttggaagt gagccagaga caagcatcat accaagaacg ataccaacgg caggatttcc
    27181 accaaataca cggaaggttg accacacaac caaacctggc aagatgatga aggctgtatc
    27241 tgtcaagatt tgtgtgtaag ttgcaaagtc acctggaagt ggcatttcaa gagcgttgaa
    27301 aagaccacgc acacccatga agagacctgt cgctacgata actgggatga ttggaacgaa
    27361 aacatcacca aaagtacgga tagcacgttg gaaccagttc ccttgtttag caacttctgc
    27421 tttcatgtca tccttagatg atgttggtaa tccaagtaca acaacttcat cgtacatttt
    27481 gttaactgta cctgtaccaa agataatttg gtattgccct gagttaaaga aagcaccttg
    27541 aactttttcc aagttctcaa tcacttcttt attgattttc tcttcatctt tgaccatgac
    27601 acgtagacga gtcgcacagt gggcaacact attgacattt tcacgtccgc ccaaggcatc
    27661 gatgactttt tttgcaattt cctgattgtt catttgcaaa aatctcctta tataacattt
    27721 tgttcttgtt tgaaagcgat tttattcgcc cttacgacta ttattttatc atgttttaaa
    27781 aatatgtcaa gcgttttgca taaaaatatt ctatccactt agtgggcaag ctttagattg
    27841 attgtttttg actgtttcat caggaattcc ttgaaaaata agtttgaaac cttggttaaa
    27901 aagtatttta tttcattatc tttcacattt tcgtaaaaat ttaattgatt tcctgtattt
    27961 attttatgat aatcgtttga cagtttttcc tcttttttaa cataaaaggc ttgcattctt
    28021 tatcgaaaac agttactatt aaaagtgata agatttttgg aggaatgaat ggaatggaca
    28081 actgagcgtc gttacagact ttatcaagat tggacgcaag aagaaattca acatataaag
    28141 gaaaatatgg cacaatctcc atggcatact cattaccatg ttgagccaaa aacaggactt
    28201 ctcaacgacc caaatggctt ttcttacttt gatggcaagt ggatcctctt ttaccagaat
    28261 tttccttttg gtgcagccca cggtttgaaa tcttgggcac agctagaaag tgatgatttg
    28321 gttcacttta aagaaactgg aatcaaagtt ttaccagata ctccattaga tagccacggt
    28381 gcctactctg gttctgccat acaatttggc gataacttat tcctatttta tacaggaaat
    28441 gttcgcgatg aaaactggat ccgtcaccca taccagatcg gtgctttgat ggacaaggag
    28501 ggtaagatta caaagattga caagatcttg attgaccagc cagcagactc tactgaccac
    28561 ttccgcgatc cacaaatttt taactttaaa ggtcaatact atgctgtcgt cggtggacag
    28621 gacttggaga aaaaaggctt cgtccgtctc tacaaggctg tcaataacga ctacacaaac
    28681 tggcaagcag ttggcgacct tgactttgct aacgaccgta ctgcctacat gatggaatgt
    28741 cctaatctgg tctttgtaga ggaacagcct gtccttctct actgtccaca aggattggat
    28801 aagaaagttc tagactacga taatatcttt ccaaatatgt ataagattgg ggcttccttt
    28861 gaccctaaaa atgccaaaat ggtagatgtg tctcaacttc aaaacatgga ttacggtttc
    28921 gaagcctatg caactcaagc cttcaacgct cctgatgggc gtgctctagc agttagctgg
    28981 cttggtttgc cagatgtttc ttacccatct gactgttttg atcaccaagg aaccttctct
    29041 ttggtcaagg aactcactat caaagacgac aagctctacc agtatccagt cgctgctatt
    29101 aaggaccttc gtgcttctga agaagccttc tcaaaccgtt cccaaaccaa gaacacttac
    29161 gaacttgaac tcaacttgga agctaatagc cagagcgaga ttgtcttact tgctgataaa
    29221 gaaggtaagg gactttcaat caactttgac cttgtaaacg gtcaagtgac agtggatcgt
    29281 agccaggctg gagaacaata tgcccaagaa tttgggacaa ctcgttcttg ccctatcgag
    29341 aatcaggcta ctactgctac aatcttcatc gataactctg tctttgaaat tttcatcaat
    29401 aaaggagaaa aagtattttc tggtcgtgtc ttcccacatg cggaccaaaa tggtatcctg
    29461 atcaaatctg gaaacccaac tggaacttac tatgaattag attatggtcg caaaactaac
    29521 tgatgtcgcc aaacttgcag gcgtcagtcc tactaccgtt tctcgggtta tcaataaaaa
    29581 aggatatcta tctgagaaaa ccatccaaaa agtcaatgaa gccatgagag aattaggcta
    29641 taaacccaac aacctggctc gtagtctgca aggaaaatca gctaagttaa tcggcttgat
    29701 tttccccaat atttccaatg ttttctatgc agaattgatt gataaattgg aacaccaact
    29761 cttcaaaaat ggttacaaga ccatcatctg caacagtgaa catgattctg agaaggaacg
    29821 cgaatacatc gaaatgttgg aagccaatca ggtagacggc atcatttctg gtagtcacaa
    29881 cctaggaatc gaagactaca atcgtgtgac agcgccgatt atttcctttg accgaaacct
    29941 atcgccagac atccctgttg tctcctctga caactatgct ggtggggttc ttgctgccca
    30001 aaccttggtc aagacaggtg cccagtctat catcatgatt acagggaatg acaattccaa
    30061 ttcgccaacc ggactgcgcc acgctggttt tgcatccgta ctcccaaaag ctcctattat
    30121 caatgtttcc agtgactttt ctcccgtcag aaaagaaatg gaaatcaaga atatcttgac
    30181 ccgggaaaaa ccagatgcca tttttgcttc ggatgatttg acagctattc tggtcattaa
    30241 aatcgctcaa gaattgggca tttctgtccc aaaagagctc aaggtcattg gctatgatgg
    30301 gacctacttt atcgaaaatt actaccctca attggctact atcaagcaac ctttggaaga
    30361 gattgcttgt ctcactattg atcttctctt gcaaaagatt gaaggcaagg aagtcgccac
    30421 aactggttac ttcttaccag ttacactatt accaggaaaa agtatttaaa cacaagaaaa
    30481 ctcagaccga ttcgtctgag ttttttatga tcttaaattt tcgagatagc gctgggctgt
    30541 ctctaggtta aaggttttat ctgcgataag ctgctcgact aggggagcaa cttcagattc
    30601 actagcccca gctaggagag ctagggattt ggcctgtagt ttcatgtggc cttgctggat
    30661 gcccgtactt accaaggctt tgagggctgc aaaattttgg gcaagaccga tggacacgat
    30721 aatctgggct aattctctgg cagaaggatt tcctagtaga tcatgactga gagctacacg
    30781 tgggttgagg ccgatagagc cacccttagt cgctacaggc atgggcaggg tcatctcacc
    30841 gaccaattct tctctttcaa ggtccagcgt ccagcaacta agaccttgat aacgtccatc
    30901 tcgactggca aaggcatggg ccccagcttc gatggcacgc cagtcattac cagtggcaat
    30961 caaaatcgca tcaataccat taaaaattcc tttattatga gtagcagctc ggtaaggatc
    31021 agcctgcgca aactgactag ccaacgcaat tttctccgca atctctcgtc cttgatcctt
    31081 ttggcggctc aagtagcgaa aggcgatgcg acagcttgca gtcaccagag aatcggtcgc
    31141 gtagttggac aggattccca tgagactctg tccctgactg agttcttcta agactggttt
    31201 caaggcttcc agcatggtgt tgagcatatt ggcacccatg gcttcctggg tatcgacatg
    31261 aatataaaca acgagaaagt ctggttcacc ttttatctgc tcgacatgca gatcacgcgc
    31321 cccaccccca cgtttaacga tagaaggata ggcttgattg gcaagctcca agagctccgc
    31381 tttcttgctg gcaatcttct cttgcgctag tttaggatta gcaacttgat aaagggctac
    31441 ctgcccaatc atctgtcgct gatggacttg tgcagtaaaa ccacctgcac gcttgatgat
    31501 tttgctggca tagctggccg ccgcaaccac agagggttct tctgtcacat agggaacggt
    31561 gtattcctga ccgttgacaa gtacctctgg aaccagtgaa taaggcagag aaaaagttcc
    31621 cactacattc tcactcagct ggtctgccac agtcacgctc atctgttcat ccttctccag
    31681 actagcttgt ctctcaggac taaggagcgc ctgagctttt aacagctcga ggcgctcttg
    31741 gtatgatttt ttagaaaatc cattccaact tatcttcatt atttttcaac cttgctataa
    31801 cggcgttggt ggtcgagaat ttcaaccaag gcaaaatctt gattttcata gccagcaaac
    31861 tgggcagagt ttgtttcatc caagtttact tcctcaaaaa agaccttttc atagtctgca
    31921 acggataggg cagttcgttg gttgagcttg ttcaaacggt ctttatccaa ataagcttca
    31981 tatccttcaa ccaattcacc actgaagaac tcagccacag ctccacttcc gtaactataa
    32041 agggcgattt tatccccagc tttcaagcta tctgtatttt ccaagagaga caaaagtcca
    32101 aggaaaagtg aacctgtgta gatattcccc accttttgac tgtagagaat agactggtca
    32161 aaatgctttt gcaagaggtc ttttttctct tgaggcaggc tcttatccat gatttttttc
    32221 aagcctttta gcgctaattt aggataaggc aagtggaaac aaacagccgc aaaatcatcc
    32281 aaagtaagct ggtagcgttt ttgatattca agccaagtcg ttttcaaact atccaagtat
    32341 tgttgggtag aatagacacc atttacataa ggagttgtcg agtaatttgg tcgccagaaa
    32401 tccatgatgt cacgggtctg agctacattg tcattattaa aggccatcat gcgtggattt
    32461 tgtgtaatca acatagctac acttccagca ccttgagttg gttctcccgg agtttcaata
    32521 ccatatttgg caatatcact ggcaatgacc aataccttgg actccggaga attttccaca
    32581 tgcaatttgg cataatggag ggcagctgtc gccccatagc aggcttcttt aatctcgaaa
    32641 ctacgagcaa agggctggat gcccagcaag ccatgcacaa agacggccgc agccttactc
    32701 tggtcaattc ctgactcggt cgccacaatg accatgtcaa cttcttgtct ttcttgctca
    32761 gttaaaatag agtcactagc actggccgcc aaggtcacga tgtcctcagt taggggcgca
    32821 atactcaatt ccttgagtaa gagtccttta cttaattttt cagggtcaat ccccctcgct
    32881 tctgctaagt cttgtaattt caagacatat tgactggtcg caaaaccaat cttatcaata
    32941 ccgattgtca tatttacctc tgttttatca ttcatgtaaa aaatcgttct atactatttt
    33001 atcacaaatg gcagtaaaag agagaaaaaa gacttgattc accaaatcaa gcctcttatt
    33061 ggtcatcatt ttaaagaatg attagttgct agagagttca ccgatataag tagctttata
    33121 agctccattc acagttatca gctcctggag gatcaaattt cctgagtaag tccttcccat
    33181 ctcatctaca aatttttgat aaaactgact ggtcggaatt tctctgacat ccttatcaaa
    33241 tgtcttgtca agtgttttac taaccttctc agcaatcaat tgatgctctt gccatccact
    33301 ttgaaactct gagcccgaac tagaaaccat gactgggata aacaacaagg tcagtagact
    33361 tacagacaat aaggaaaata gtagacttcc tgcaaaacta gaatcctagt tcatgattga
    33421 taatacca
//
LOCUS       DBERPV010000021        31956 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.21, whole genome shotgun sequence.
ACCESSION   DBERPV010000021 DBERPV010000000
VERSION     DBERPV010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 31956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31956
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.21"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..333
                     /locus_tag="ACL8C7_001253"
     CDS             <1..333
                     /locus_tag="ACL8C7_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGS1395458.1"
                     /translation="INVKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMT
                     SSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLG
                     LKNKKEEN"
     gene            500..1198
                     /locus_tag="ACL8C7_001254"
     CDS             500..1198
                     /locus_tag="ACL8C7_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS1395459.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            1195..2247
                     /locus_tag="ACL8C7_001255"
     CDS             1195..2247
                     /locus_tag="ACL8C7_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGS1395460.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            2442..3053
                     /gene="rpsD"
                     /locus_tag="ACL8C7_001256"
     CDS             2442..3053
                     /gene="rpsD"
                     /locus_tag="ACL8C7_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HGS1395461.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            3238..3393
                     /locus_tag="ACL8C7_001257"
                     /pseudo
     CDS             3238..3393
                     /locus_tag="ACL8C7_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
     gene            3819..4040
                     /locus_tag="ACL8C7_001258"
     CDS             3819..4040
                     /locus_tag="ACL8C7_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395462.1"
                     /translation="MTGVSNPTTDSAPLVLAEAKKAFADDSLIEQGLRDILQTVKDAI
                     ASLESIKESQSATKIDNLKEVITKLKANA"
     gene            4359..5288
                     /locus_tag="ACL8C7_001259"
     CDS             4359..5288
                     /locus_tag="ACL8C7_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1395463.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            5302..6225
                     /locus_tag="ACL8C7_001260"
     CDS             5302..6225
                     /locus_tag="ACL8C7_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS1395464.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            6483..7958
                     /locus_tag="ACL8C7_001261"
     CDS             6483..7958
                     /locus_tag="ACL8C7_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS1395465.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            8230..9216
                     /locus_tag="ACL8C7_001262"
     CDS             8230..9216
                     /locus_tag="ACL8C7_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HGS1395466.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            9338..10198
                     /locus_tag="ACL8C7_001263"
     CDS             9338..10198
                     /locus_tag="ACL8C7_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 family protein"
                     /protein_id="HGS1395467.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWLIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPPSFYHQLDANQIEIQPILG
                     QDFKTLAQEK"
     gene            complement(10376..11440)
                     /locus_tag="ACL8C7_001264"
     CDS             complement(10376..11440)
                     /locus_tag="ACL8C7_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6574 domain-containing protein"
                     /protein_id="HGS1395468.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEERITDLDTPIEK
                     NTQLEEEVSQAEVELESQQEEKIETPEDSEARTKIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPYQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(11503..12414)
                     /locus_tag="ACL8C7_001265"
     CDS             complement(11503..12414)
                     /locus_tag="ACL8C7_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HGS1395469.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTDNHFHAEN
                     IQVHGKVELTAKDYLRIILDQKENQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            complement(12407..13000)
                     /locus_tag="ACL8C7_001266"
     CDS             complement(12407..13000)
                     /locus_tag="ACL8C7_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HGS1395470.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKRKRGNQHA"
     gene            complement(12987..13313)
                     /locus_tag="ACL8C7_001267"
     CDS             complement(12987..13313)
                     /locus_tag="ACL8C7_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGS1395471.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGS
                     IRHDKN"
     gene            complement(13452..14618)
                     /locus_tag="ACL8C7_001268"
     CDS             complement(13452..14618)
                     /locus_tag="ACL8C7_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HGS1395472.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVIGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL"
     gene            14676..15833
                     /locus_tag="ACL8C7_001269"
     CDS             14676..15833
                     /locus_tag="ACL8C7_001269"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGS1395473.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKGTIIYLDKISQINQNML"
     gene            15875..17725
                     /locus_tag="ACL8C7_001270"
     CDS             15875..17725
                     /locus_tag="ACL8C7_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HGS1395474.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVARAVDEAKVPKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(18028..18660)
                     /locus_tag="ACL8C7_001271"
     CDS             complement(18028..18660)
                     /locus_tag="ACL8C7_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGS1395475.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(18682..19554)
                     /gene="sdaAA"
                     /locus_tag="ACL8C7_001272"
     CDS             complement(18682..19554)
                     /gene="sdaAA"
                     /locus_tag="ACL8C7_001272"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HGS1395476.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            complement(19563..20234)
                     /gene="sdaAB"
                     /locus_tag="ACL8C7_001273"
     CDS             complement(19563..20234)
                     /gene="sdaAB"
                     /locus_tag="ACL8C7_001273"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HGS1395477.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            20476..21063
                     /locus_tag="ACL8C7_001274"
     CDS             20476..21063
                     /locus_tag="ACL8C7_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGS1395478.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            complement(21115..21441)
                     /locus_tag="ACL8C7_001275"
                     /pseudo
     CDS             complement(21115..21441)
                     /locus_tag="ACL8C7_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            22192..22560
                     /locus_tag="ACL8C7_001276"
     CDS             22192..22560
                     /locus_tag="ACL8C7_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0218 family bacteriocin-like peptide"
                     /protein_id="HGS1395479.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAIYIPRWAITGAITGAAYAAL
                     AAGGGGLQLVLASYGLRSALVAGIVKGLGVLGIHIGNAFANTVIRSIASAGIGAGADW
                     IFTNIIDGWDGRRDNQLRIG"
     gene            22568..22780
                     /locus_tag="ACL8C7_001277"
     CDS             22568..22780
                     /locus_tag="ACL8C7_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000973716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395480.1"
                     /translation="MLIVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQIK"
     gene            23154..23279
                     /locus_tag="ACL8C7_001278"
     CDS             23154..23279
                     /locus_tag="ACL8C7_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395481.1"
                     /translation="MATITNALNIAATVAEVFSLGGAIAYGLDIVDGKFDGYLWA"
     gene            23260..23505
                     /locus_tag="ACL8C7_001279"
     CDS             23260..23505
                     /locus_tag="ACL8C7_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395482.1"
                     /translation="MGIYGRKTIAMKYFFAGIGEIHFLLFLLYLSMSASPIIGLVIGY
                     TKINLINSIIIALGMILALILVLSRVYRKYFYRDDDD"
     gene            23662..24720
                     /locus_tag="ACL8C7_001280"
     CDS             23662..24720
                     /locus_tag="ACL8C7_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395483.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPLSVFTFIFSYILLFVQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYVKEISSARYSEYLTCEYKNLTPIILIAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCVPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            25035..26012
                     /locus_tag="ACL8C7_001281"
     CDS             25035..26012
                     /locus_tag="ACL8C7_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395484.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFISVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLISFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINNPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYIGIKHVSIRR"
     gene            26389..26763
                     /locus_tag="ACL8C7_001282"
     CDS             26389..26763
                     /locus_tag="ACL8C7_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HGS1395485.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGFSILRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            26770..26952
                     /locus_tag="ACL8C7_001283"
     CDS             26770..26952
                     /locus_tag="ACL8C7_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395486.1"
                     /translation="MGIKMEKIFVIIFFVCLFISSITFLAYDFVSEEIKKLIIWMNVV
                     FLILIIAMIIYPKLRK"
     gene            26971..27873
                     /locus_tag="ACL8C7_001284"
     CDS             26971..27873
                     /locus_tag="ACL8C7_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395487.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHLLVSNLQLNLEIPLDFVVSTSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTKTLKDKIQKSELSYSDLMSLQLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEMSISNNNNWSNKVDKIRIHLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            27929..28261
                     /locus_tag="ACL8C7_001285"
     CDS             27929..28261
                     /locus_tag="ACL8C7_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HGS1395488.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKRACQGICVALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGKIAYCIGYGALNRGCDISGNPYPWD
                     GFISATVR"
     gene            28258..28986
                     /locus_tag="ACL8C7_001286"
     CDS             28258..28986
                     /locus_tag="ACL8C7_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395489.1"
                     /translation="MNNVDKIRKIHIIVCWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IGEDFATKLTNEYKKISQFRSKVSQSSWIKYLEISSFILTIFPSILYGTVDNRVLALI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKAKEYELFKNSK"
     gene            29465..29662
                     /locus_tag="ACL8C7_001287"
     CDS             29465..29662
                     /locus_tag="ACL8C7_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395490.1"
                     /translation="MKHFFAGIGEIKLVGYLLYICVGLALLFHIYVIGSELSFVKIVL
                     SILGVIFVSMLTIARIYRTFL"
     gene            30119..30358
                     /locus_tag="ACL8C7_001288"
     CDS             30119..30358
                     /locus_tag="ACL8C7_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395491.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            30911..>31956
                     /locus_tag="ACL8C7_001289"
     CDS             30911..>31956
                     /locus_tag="ACL8C7_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HGS1395492.1"
                     /translation="MNKKKMILTSLASVAILGAGFVASQPTVVRAEEAPVAKQSQAER
                     DYDAAMKKSEAAKKEYEEAKKDLEEAKAAQKKYEDDQKKTEEKAKLVQKADEERQKAN
                     VAVQKAYLKLREAQEQLNKSPNNKKNAAQQKLKDALAHIDEVTLKQKEAEANFNKEQA
                     KVVPEADKLAETKKKAEQAEKKEPELAKKVAEAKAKAEEAEKKAVEAKQKVDAEKYAL
                     EAKIAELEYEVQGLEKELKEIDESDSEDYIKEGLRAPLQSKLDAKKAKLSKLEELSDK
                     IDELDAEIAKLEKDVEDFKNSDGEQAEQYLVAAKKDLDAKKAELENTEADLKKAVDEP
                     ETPAPAPAPKPAPAP"
BASE COUNT        10009 a         5382 c         6570 g         9995 t
ORIGIN      
        1 ataaatgtta aagaaacatc agacacagca aatggttcat tatcaccttc taactctggt
       61 tctggcgtga ctccgatgaa tcacaatcat gctacaggta ctacagatag catgcctgct
      121 gacaccatga caagttctac caacacgatg gcaggtgaaa acatggctgc ttctgctaac
      181 aagatgtctg atacgatgat gtcagaggat aaagctatgc taccaaatac tggtgagact
      241 caaacatcaa tggcaagtat tggtttcctt gggcttgcgc ttgcaggttt actcggtggt
      301 ctaggtttga aaaacaaaaa agaagaaaac taatcagcta aggaaataaa tgatggatag
      361 tgggctgact aagattagtt taacaactca atcagcaatc aggactttct ttcaatagca
      421 gattaaaatc atcgtaaaac aataaaaata gtgttatact taaagcagta tagcactgtt
      481 tttatcaaag gagagacaga tgggaaagac aattttactc gttgacgacg aggtagaaat
      541 cacagatatt catcagagat acttaattca ggcaggttat caggtcttgg tagcccatga
      601 tggactggaa gcgctagagc tgttcaagaa aaaaccgatt gatttgatta tcacagatgt
      661 catgatgcct cggatggatg gttatgattt aatcagtgag gttcaatact tatcaccaga
      721 gcagcctttc ctatttatta ctgctaagac cagtgaacag gacaagattt acggcctgag
      781 cttgggagca gatgatttta ttgctaagcc ttttagccca cgtgagctag ttttgcgtgt
      841 ccacaatatt ttgcgccgcc ttcatcgtgg gggcgaaaca gagctgattt cccttggcaa
      901 tctaaaaatg aatcatagta gtcatgaagt tcaaatagga gaagaaatgc tggatttaac
      961 tgttaaatca tttgaattgc tgtggatttt agctagcaat ccagagcgag ttttctccaa
     1021 gacagacctc tatgaaaaga tctggaaaga agactacgtg gatgacacca ataccttgaa
     1081 tgtgcatatc catgctcttc gacaggagct ggcaaaatat agtagtgacc aaacgcccac
     1141 tattaagaca gtttgggggt tgggatataa gatagagaaa ccgagaggac aaacatgaaa
     1201 ctaaaaagtt atattttggt tggatatatt atttcaaccc tcttaaccat tttggttgtt
     1261 ttttgggctg ttcaaaaaat gctgattgcg aaaggcgaga tttacttttt gcttgggatg
     1321 accatcgttg ccagccttgt cggtgctggg attagtctct ttctcctatt gccagtcttt
     1381 acgtcgttgg gcaaactcaa ggagcatgcc aagcgggtag cggccaagga ttttccttca
     1441 aatttggagg ttcaaggtcc tgtagaattt cagcaattag ggcaaacttt taatgagatg
     1501 tcccatgatt tgcaggtaag ctttgattcc ttggaagaaa gcgaacgaga aaagggcttg
     1561 atgattgccc agttgtcgca tgatattaag acccctatca cttcgattca agcgacggta
     1621 gaagggattt tggatgggat tatcaaggag tcggagcaag ctcattatct agcaaccatt
     1681 ggacgccaga cggagaggct caataaactg gttgaggagt tgaatttttt gaccctaaac
     1741 acagctagaa atcaggtgga aactaccagt aaagacagta tttttctgga caagctctta
     1801 attgagtgca tgagtgaatt tcagtttttg attgagcagg agagaagaga tgtccacttg
     1861 caggtaatcc cagagtctgc ccggattgag ggagattatg ctaagctttc tcgtatcttg
     1921 gtgaatctgg tcgataacgc ttttaaatat tctgctccag gaaccaagct ggaagtggtg
     1981 gctaagctgg agaaggacca gctttcaatc agtgtgaccg atgaagggca gggtattgcc
     2041 ccagaggatt tggaaaatat tttcaaacgt ctttatcgtg tcgaaacttc gcgtaacatg
     2101 aagacaggtg gtcatggatt aggacttgcg attgcgcgtg aattggccca tcaattgggt
     2161 ggggaaatca cagtcagcag ccagtacggt ctaggaagta cctttaccct cgttctcaac
     2221 ctctctggta gtgaaaataa agcctaaaac ccctttacaa atccagctat tcatggtaga
     2281 atagattttg tgtgaaatat cagcaggaaa gcatgaagct cgtcaacagg tgtcttatga
     2341 caagtaacct tggctgttta ggcgaagggc atctgcacga atcagggctt tctaagtgac
     2401 tatttccacc gaaatattat ttatatcagg aggacattca tatgtcacgt tatacaggac
     2461 catcttggaa acaagctcgt cgccttggcc tttcacttac aggtacaggt aaagaattgg
     2521 cacgtcgtaa ctacgtacca ggacaacacg gaccaaacaa ccgttctaaa ttgtcagaat
     2581 acggtttgca attggctgaa aaacaaaaac ttcgtttcac ttacggtgta ggtgaaaaac
     2641 aattccgtaa cttgttcgta caagctacaa aaatcaaagg cggaatccta ggtttcaact
     2701 ttatgcttct tttggaacgt cgtttggata acgttgttta ccgtcttggt ctcgcgacta
     2761 ctcgtcgtca agctcgtcaa ttcgtaaacc acggtcacat ccttgttgac gggaaacgcg
     2821 ttgatatccc atcataccgc gtaactccag gtcaagtgat ctcagttcgt gaaaaatcat
     2881 tgaaagttcc agcaatcctt gaagcagtag aagctactct tggacgtcca gcattcgtat
     2941 cattcgacgc tgaaaagttg gaaggttcat tgactcgctt gccagaacgc gacgaaatca
     3001 acccagaaat caacgaagca cttgtcgttg aattctacaa caaaatgttg taatatttta
     3061 ttaaataaga taggctttga ggccttgata ttaagcactt tgggacgttc tcccttagtg
     3121 cttttttgat ttctcttagt atccagctat aatcgtttag acataactag accgatatag
     3181 tccaaagtga tatagtaaaa tgaaccaaaa atagtacaca atgtggtata atcttttatg
     3241 gcatattcaa tagattttcg taaaaaagtt ctctcttatt gtgagcgaac aggtagtata
     3301 acagaagcat cacacgtttt tcaaatctca cgtaatacca tttatggctg gttaaagcta
     3361 aaagagaaaa caggagagct aaaccaccaa gtatagtgta ttgaatctat aacagtacac
     3421 cttggctgct aaaatatttc tataaattaa tttgactttc ctgatagagt tgttcacatc
     3481 ttatttcaaa ctactataaa agttctataa tctctttata agatttgccc atcagacgaa
     3541 atataatgga ttgaaactag aatagtacac ctctacttct aaaacattgt tagaaatcga
     3601 tttgactgtc ctgatcgatt tgtcctgttc ttgtttcatt ttactataga acgatttgaa
     3661 ggcgtttatg atatttagct gtatgagagt cttttaaaag tgttttgatg gtttggattt
     3721 cttctttagt tgatttcata tcactgttat ataatgcttt ttgatttgag tctagtatta
     3781 gtaagcagac tcaaacctta gaaaatcttt tgagatcatt gacaggtgta tcgaatccta
     3841 ccacagattc agcacctctg gttttggcag aggctaagaa agcttttgca gatgatagtt
     3901 tgatagagca aggtttacgt gatatcttgc aaacagtcaa agatgccatt gcttccctag
     3961 agtccattaa ggaaagccag tcagcaacta agattgataa tcttaaagag gttattacta
     4021 agttgaaagc aaacgcctaa taacatatta aaaatctcca gattaggaac tatcgctgag
     4081 ttccctagtc tggagatttt tcagtatacc ccgttgttgg atacttataa cagagtgacg
     4141 ccatcactgg gctaatagag ataaaataaa caattgattt aggacatttg tttgatagtg
     4201 gtgataaagt tttaaatctg ctacataatt tgtggagttt tttctataat taggagttta
     4261 acctaacctg caaataggag tatactaata atgtaatcgt tatcaaaagt ctaaaaaaga
     4321 atttttagat ggatatcaaa ataaaaaggg aggaaattat gaaaaagttt tcaaaaacat
     4381 tgagagacaa ctggatcttt ctcttgatgg ttttgccagg ggcactctgg ttgattctat
     4441 tcttttacat tccagtattt gggaacgtgg ttgccttcaa agactaccac atgaccagta
     4501 atggtttcat agatagtatc ataaatagta aatgggtcgg actcgataat ttcagattct
     4561 tatttagttc aagagacgcc tttattatca cacgaaatac tgtcctctac aatcttggct
     4621 ttatctttct aggtttagtt gtatctgtag ggattgccat tatcctcagc gagctccgtt
     4681 ctaagagaat ggtgaagatt ttccaaactt ctatgttgtt cccttacttc ttgtcttggg
     4741 ttatcatcag tttctttaca gatgccttcc taaatattga taaaggggtg ttcaatcatc
     4801 tattggaaag tcttggtctc aaagaagtca atttttacgc tgacctgggc atctggccct
     4861 atctcctact tttcctaggt atttggaaag gctttggata tagcagtgtc atgtactatg
     4921 cgacgatcat gggaattgat ccaacctact acgaagcagc gacagtggac ggagctagca
     4981 agtggcaacg tattcgcaac gtaaccattc ctcagttgac tccgcttgta actgtattga
     5041 ccatccttgc agtcggaaat atcttccgcg cagacttcgg tctcttctat caaatcccac
     5101 acaatgctgg tcagctttac aatgtaacca acgttttgga cgtatatgtc tttaatggtt
     5161 tgactcagac agcagatatc ggtatggctg cagcagccgg tctttaccaa tccgttgttg
     5221 gtttgattct ggttatccta tcaaacttgc ttgcaagacg agtcgatcca aactcagctt
     5281 tgttctagaa aggaggagaa tatggcaaaa aagaaaatta aaaaagaaaa aattgataat
     5341 gtcggcattc actccttcag taagaaagca gatatcttct tcagtatcat ttcgggtttg
     5401 attgccctct cttgtatcct accttttgta ttcgttatca ttatttcagt gacagacgag
     5461 aaaagcctcc tccaatacgg ctatagcttc ttcccatccc aatttggctt agacggtttt
     5521 gagtttttgg cacagtttaa ggataaaatc ctacaagccc tcttcatctc tgtctttgta
     5581 accgtagttg ggacattgac aaatgtcttt atcacaacaa cctatgccta cgctatttca
     5641 cggacaacct ttaagtatcg cagatttttt accatcttcg tccttctcag tatgttgttc
     5701 aacgctggtt tggtaccagg ttatatcatg gtgacccgtg tacttcagct tggtgacact
     5761 gtttgggcct tgattgtgcc aatgcttctc tcccccttta acatcatctt gatgcgttcc
     5821 ttcttcaaga agaccattcc agaagccatt ctcgaatcgg ctcgtatcga tggtgccagt
     5881 gaggcccgga ttttcttcca aatctgtttg ccattgtcac taccaggtat cgcaaccatc
     5941 acgcttttga cagctcttgg tttctggaat gactggttca acgcccttct ttacatcaag
     6001 agtgataact tgtatccatt gcaatatttg ctcatgcaaa tccaacaaaa tatggactac
     6061 attgccaaag cggtcggctt gactggtcaa ctgggagttg ctctaccgaa agaaacaggt
     6121 cgtatggcca tggttgtggt tgcaaccctt ccaatcgcga ttttatatcc attcttccaa
     6181 cgctactttg taaaaggttt gactatcggt ggtgtgaaag aatagtgctt attgaaaaag
     6241 aacatttctc agttcccaac ttcccttgtg tgaagttaat actcttcgaa aatcaaattc
     6301 aaaccgcgtc aacgtcgcct tgccgtagat atatgtaact gacttcgtca gtcttatcta
     6361 caacctcaaa gcagtgcttt gagcagcctg cggctagttt tctagtttgc tctttgattt
     6421 tcattgagta taagatcatt acattgttta taagtttaaa aataaaaaaa ggagttttta
     6481 tcatgaaaaa ctggaaaaaa tatgcttttg catctgctag tgtagtcgct ttggctgcag
     6541 gtcttgctgc ttgtggcaac ttgacaggta acagtaaaaa agctgctgat tcaggtgaca
     6601 aacctgttat caaaatgtac caaatcggtg acaaaccaga caacttggat gaattgttag
     6661 caaatgccaa caaaatcatt gaagaaaaag ttggtgccaa attggatatc caataccttg
     6721 gctggggtga ctatggtaag aaaatgtcag ttatcacatc atctggtgaa aactatgata
     6781 tcgcctttgc agataactat attgtaaatg ctcaaaaagg tgcttatgct gacttgacag
     6841 aattgtacaa aaaagaaggt aaagaccttt acaaggcact tgatccagct tatatcaagg
     6901 gtaatactgt aaatggtaag atttacgctg taccagttgc agccaacgta gcatcatctc
     6961 aaaactttgc cttcaacgga actctccttg ccaaatatgg tatcgatatt tcaggtgtta
     7021 cttcttacga aactcttgag ccagtcttga aacaaatcaa agaaaaagct ccagacgtag
     7081 taccatttgc tattggtaaa gttttcatcc catctgataa ctttgactac ccagtagcaa
     7141 acgggcttcc attcgttatt gaccttgaag gcgatactac taaagttgta aaccgttacg
     7201 aagtgcctcg tttcaaagaa cacttgaaga ctcttcacaa attctatgaa gctggctaca
     7261 ttccaaaaga cgtcgcaaca agtgacactt catttgacct tcaacaagat acttggttcg
     7321 ttcgtgaaga aacagtagga ccagctgact acggtaacag cttgctttca cgtgttgcca
     7381 acaaagatat ccaaatcaaa ccaattacta acttcatcaa gaaaaaccaa acaacacaag
     7441 ttgctaactt tgtcatctca aacaactcta agaacaaaga aaaatcaatg gaaatcttga
     7501 acctcttgaa tacgaaccca gaactcttga acggtcttgt ttacggtcca gaaggcaaga
     7561 actgggaaaa aattgaaggt aaagaaaacc gtgttcgcgt tcttgatggc tacaaaggaa
     7621 acactcacat gggtggatgg aacactggta acaactggat cctttacatc aacgaaaacg
     7681 ttacagacca acaaatcgaa aattctaaga aagaattggc agaagctaaa gaatctccag
     7741 cgcttggatt tatcttcaat actgacaatg tgaaatctga aatctcagct attgctaaca
     7801 caatgcaaca atttgataca gctatcaaca ctggtactgt agacccagat aaagcgattc
     7861 cagaattgat ggaaaaattg aaatctgaag gtgcctacga aaaagtattg aacgaaatgc
     7921 aaaaacaata cgatgaattc ttgaaaaaca aaaaataatc agctaaattg atttcgtgta
     7981 ttcattccta actcctaaaa taagaatcac tgctttcctc aggttggtct ggggagggca
     8041 gtggtttttt tggcacaagg atatagatat ccatgttttc tcttgtcctt attttaacca
     8101 ttcaggaaat ttcgagaacc ctctacaatt tccagtcaaa taaattgcat tcgttttttc
     8161 aagcaggtat actagtatag ataaataaaa aatttagaaa atttaagaat agaaaagaga
     8221 acaaatctta tggcaaaaga tattcgtgtc ttactttact acctttatac tccaattgaa
     8281 aacgcagagc aatttgctgc agaccacttg gctttctgta aatcaatcgg ccttaaaggc
     8341 cgtatcctag tcgctgacga gggaattaac ggaacagttt caggtgacta tgaaacaact
     8401 caaaaataca tggactacgt tcacagcctt ccaggaatgg aagatctctg gttcaagatt
     8461 gacgaagaaa atgaacaagc cttcaagaag atgtttgttc gctacaagaa agaaattgtc
     8521 caccttggtt tggaagacaa cgactttgac aatgacatca acccacttga aacaacaggt
     8581 gcttacttgt ctccaaaaga gttcaaagaa gcgcttcttg ataaagatac cgttgtcctt
     8641 gacacacgta acgattatga gtacgaccta ggacatttcc gtggggctat tcgcccagat
     8701 attcgcaact tccgtgagtt accacaatgg gtccgtgaca acaaagaaaa attcatggac
     8761 aagcgtgtcg tggtttactg tacaggtggt gttcgctgtg agaaattctc aggctggatg
     8821 gttcgtgaag gttacaaaga tgttggccaa ttgcacggag gaatcgcaac ttacggtaaa
     8881 gacccagaag ttcaaggtga gctttgggat gggaaaatgt acgtctttga cgagcgtatt
     8941 gccgttgatg tcaaccatgt caacccaact atcgtaggga aagactggtt tgatggaacg
     9001 ccatgtgaac gttatgtcaa ctgtggaaat cccttctgta accgtcgtat cttgacatca
     9061 gaagaaaatg aagacaagta ccttcgtgga tgctcacacg agtgccgtgt tcacccacgt
     9121 aaccgctatg tttcaaaaaa tgaattgaca caagctgaag tgatcgagcg cctagccgct
     9181 atcggtgaaa gcttggatca agcagctact gtataagatc aaacagtcct caggggctgt
     9241 ttttctatgc tttgtactca aaaatctaaa gtttgtttct gtatctttca gaaaaataag
     9301 gtatactgtg tgtaagcgat ttcaaaggag tccagttatg gcgaaaacat tttttattcc
     9361 aaataaacag agcattttag gagaacaaga gattttgaat gccaagtcga tcttggcctt
     9421 gctagacggt ttggagtcac atagctatga tgtagtctat ctccgtcagc ctcttaatcg
     9481 tctcgaatat attgagtgtg cgatagtggg gcaatcacaa tttcttttta aggtcagtta
     9541 tgctgatggt caaaaggctt accgtgtcga tcttcctgac ctactaacaa agacagactg
     9601 gctgattatc aagtcatttt tagatgcttt gcttgcttat acagggactg atattgaagg
     9661 gctagatggt tttgattttg aagcttattt ccaagcaagt attcaagcct atctagcaga
     9721 ccctgtagct cgttttacga tttgccaagg aatttttaat cctattttct ttagtcgtga
     9781 gaacttgaaa agctttttag aggcagatgg cttggctcag tttgaagcgc gtgtgcgtgc
     9841 ggttcaagag acagatgcct actttgcgag agtttccttc tatcaggatg gagaaggaaa
     9901 agtgcatggc gtttaccatc tagctcaagg agtcaagaca gttttaccga gagaaccgtt
     9961 tgttcctgca gcctatattg agcaattggt ggataaggaa gtccagtggg agattgactt
    10021 ggttcaaatc acaggagacg gctctaaacc agaagactat gaagccattg cccgcttgga
    10081 ctatgcaaaa ttcttagagg tattaccccc atctttttac caccagctag acgccaatca
    10141 aatagaaata caacccatcc taggacaaga ttttaaaaca ttagcacaag aaaagtaaag
    10201 cagaagcagg tcaatcgact tgcttttttg acatagaaaa aatcctgcca aggatgacag
    10261 gattgctact caatgaaaat caaagagcaa actaggaagc tagccgcagg ctgtacttga
    10321 gtacggtaag gcgaagctga cgtggtttga atttgatttt cgaagagtat gaagtttaaa
    10381 gaaaggccaa gatacgaaga taatctccaa tcagtgccac ttcagctaca aagaagagga
    10441 ggataataac tccgttcaca aggacagaca agaataattg atagaaggag tcggtttcac
    10501 ttgcttgact tggtcttgta atgatatgga gactggcaag cagaatgatt ccaatgctaa
    10561 ttacacacaa gagagctgta aatcgtaggc tatcaaagaa agcaaagaaa ctagcaatag
    10621 cagtgaggaa gattggaatt gccaagagtt gactatattg ttggagaacc ttgtctagcg
    10681 tccagtcctt ttcctggtgg ataaatcgtc tcacaacgaa actacccaag aggaatgaaa
    10741 agaagaagag tgttgtcgct actaggatag agatgataga aaaaagagtt aaaggagcta
    10801 gctgctcagg gaagcgactg ttaatgcttg ctatatgtcc atagtaagca tgtttgatgt
    10861 gatagatact aaagaaaaag gaagatgcag aaaacagaat gagcaagaga aaggctgtgt
    10921 aactgtgtgt gatacttgtt tccaacttac ttgtaggaga tttgatcgct tccactagcc
    10981 aagaccaaaa atcaagcact tgctctttcc atttatccct agattttgga gcttggtagg
    11041 ggatataagg actttctaaa gatttactga taagaagtgg ctctttcgta gttgcttttt
    11101 gctgaggaag agcttcttgg ctctcttcag ctatagtgac tttttctgtt tctttagaaa
    11161 ggtctggctc ttcttcagta gaattagatg ccttcttttc ttctattttt gttctcgctt
    11221 cactgtcttc aggagtttca attttctctt cttgctggct ttccaattcg acttcagctt
    11281 gagagacttc ctcctctaac tgagtatttt tttcaattgg tgtatcgagg tcggttatcc
    11341 tttcttcagc cttgtctgca acctcttgag cttgctcttc aggcttgttc ttgcttgttg
    11401 tttttacaaa atcattactt tcaaaccatt cttgtttcat ggtagaacct cctttttagt
    11461 tagataaata tgcttccata gtagcagatg taagcgtttt tgtcaacgtc tgcttggtgt
    11521 ggatattaga tcaatattat catcagatct cgcaatgagt tgatccttga catcggtttt
    11581 ttcagttttg taagggttgc ttaattccgt acctcttgat tcaggctttt ctcttgtgaa
    11641 ttggaagata gaaccatagt tgcttgagat gtcccagtta attcgttggt tttctttctg
    11701 gtctaggatg attctgagat aatctttggc agtcagttca accttaccat ggacttggat
    11761 attttcagcg tggaagtgat tatctgttga ctctagctga ctatctgtaa gaactgtatc
    11821 aaagatatta acgatattgg gcgttgtgag tttactgttt ttgatacgac ttccttcaat
    11881 tcggaggata tagctgtttg tattgagggt cgcattttca aggctagcat ttatgatggt
    11941 ggtttgtccg cgattggctg agatgttgat cccttttaga gttctccctt ttggtagtcg
    12001 gagaataact tcttcaaaac gactagagta gctacttgcg atatgaagaa tcccaccaat
    12061 tccagaagag agaaacggag tttcagacag tttcttatca gtgagactca gagttctatc
    12121 gttctgattg gtgataagat catggtgagc agaaagagat ggatggtaag aaatgtggat
    12181 ttgatcatcg aaagagtctg tgatggtgag cgtgtgttgg tggagagtaa tttctaggtt
    12241 ttcgacttcc ttgccaaagg ttagcttttc cgtacggcta tcatagacag gttctttgga
    12301 catggaaagt aggctcttaa tcccgtcaga ttggatacct acaaaaagca ggataaagcc
    12361 gataacggta gtcaccacac caaagatgag aaatcctttt gtccatttac gcatgctggt
    12421 tacctctctt tcttttttta agaacaaatt gtaccaggcg aacaatgagt agaccgaaga
    12481 agcgagctac ataggaaatg cctagtaaaa ctagcgaaga agcaccgata gccagtaaac
    12541 cagaaccaaa aatcaagata aaggctgatt tggcttgggc gaggacagtg aaactttcaa
    12601 ctaaaaatag gaatccgccg atgataccca gtatggaaac tgcaaagaaa gccagaatga
    12661 cagtcaaagc ggctacaagg attgcgaaca gggtcacgag gatggcgatt cccagaggaa
    12721 tgccgatagg tgctgcaagg agggctaaca aggcgatatg taaaatttgt cggttatttt
    12781 tttgagcggg tgcttcattg atttttttat cgagaagatt ggatagaact tcgtgggccg
    12841 cttctttggg agttcccaaa ctagcgatga gttcttcttc tccttcgact ccagcatcgt
    12901 caaagagctc tctgaaatag tccatggctt cgatacggtc agcttcaggt agtttcttga
    12961 gatagagttc tagctgagtc aggtattcag ttcttgtcat ggcggatact cccttctatg
    13021 atgccattga tggtgtctgt atagagtgtc cattcatctt ttagggtcaa gagctgctct
    13081 ataccaccgt ttgtcaagga gtagtatttg cgcatgcgac cttggaactc tctagaatag
    13141 gttgtcagaa agctattgcc ttccaatttt ttgagaatgg gatagagtgt ggattctttg
    13201 atattagcga tcagcttaat ggtttggcta atctcataac cataagaatc accctgctcc
    13261 agtacagcca agatgagaaa ttcaatcaag gcagaggatg ttggaaagta catgggaaac
    13321 ctccttttct aatgtgtaag atttttatat ataatttttc tacacataca ttgtacatct
    13381 aaaagaaagc cctgtcaaga gaaatgtgta aaatttttat atataaaaaa cttctagcta
    13441 aaactagaag tttaaaggat cttatccgct ctgtccactg taaagagggc cacagtcatc
    13501 aggatatcga tgagcaagag ggcagctaca gctggtaccc aagagtggaa caggtcaaaa
    13561 ctgtaaccaa agagggttgg cccaaaggct gctaggatat agcctcctgt ttgagatagg
    13621 ccggacaatt gggctgtctt ttcaggggcg cttgtcttga gtgaaaagtt gaccatgaga
    13681 taagggaaga gggcgctggt tgcggttccg atgaggagat ggatggcaag ccagtaaatg
    13741 aaattattga ttgggaaaaa gagcatggaa atgccgatca caccagctag tgaaaccaga
    13801 gtgagcatga gctgacggtt gcgagtagat aaactggttg tcaggcttgg gatggtcatt
    13861 gaaaaaggaa tgctaatcag agataagata gaagtcagca agccagcttc gtgactggat
    13921 agacctgcat ggatagacat ggtaggtaac caggtcatga cggtgtaaaa gatcaaggat
    13981 tgaaaacctg aaaagataat aattgcccaa acctgtttat tacgcatgac ctttatttga
    14041 cttttttgtt tggtttgtgg agctagtcta tgattatagc ggtgatttgg gagccagacc
    14101 aaaaaagttg ctagacagag taacgtgagg agaaggataa gtcctttcca agaactggct
    14161 tgtgtaatgg gcacagctag ataggaagcc agagccgttg caatccccat agacgttaca
    14221 tataaggtgg tcagaaaacc aattttcttt ggttgattgg cttggataag actaggaagc
    14281 aggacattga tgactgcgac acttgcccca accatcaagg ttcctagata gagtaggggc
    14341 agattgatta gtcgaataag tgagccgatg gtcaagaaga agaggctgta ggtgaagaga
    14401 tgctccaagc cgattttctg agccagttgg gtagaaaatg gtgaaaagag ggtaaacata
    14461 aggagaggca ggctggtcaa gacaccaagc gaactaactt ctacctccag accttgcgaa
    14521 atatttccca aaataatggg taaaacagta aaaggagttc gcaaggaaac accaatcagg
    14581 ataatacctg gaacaaaaaa gagtgattgc tttttcatat aatacctctt atagctgatt
    14641 ttaataacag cttattttaa ggctttttca ctataatgtc aagtaaggtt tctggctttc
    14701 aagataaaaa tgggaaagtc ttgaaaatta tgatagaatg gtggaaggaa aaattcagga
    14761 gagtagtagt gactcaaaat gttgaaagtc ttctcgtatc cattgtaatc agtgcataca
    14821 atgaagaaaa atatctgcct ggtctaattg aagacttaaa aaatcaaacc tatcctaaag
    14881 agaatattga aattctattt ataaatgcta tgtccacaga tgggaccaca gctatcattc
    14941 agcaatttat aaaggaagat acagagttta actcaattag attgtataac aatcctaaga
    15001 aaaatcaagc tagtggtttt aacctgggag ttaaacattc tgtaggggac cttattttaa
    15061 aaattgatgc tcattcaaaa gttactgaga gttttgtaat gaacaatgtg gctattattc
    15121 aacaaggtga atttgtctgt ggggggccta gaccgacgat tgtcgaagga aaaggaaaat
    15181 gggcagagac cttgcatctt gttgaggaaa atatgtttgg cagtagcatt gccaattatc
    15241 gaaatagttc tgaggataga tatgtttctt ctatttttca tgggatgtat aaacgagagg
    15301 ttttccagaa ggttggttta gtaaatgagc aacttggccg aactgaagat aatgatattc
    15361 attatagaat tcgagaacat ggttataaaa ttcgctatag cccaagtatt ctatcttatc
    15421 agtatattcg accaacattc aagaaaatgc tgcatcaaaa gtattcaaat ggtttgtgga
    15481 ttggcttgac aagtcatgtt cagtttaagt gtttatcatt atttcactat gttccttgtt
    15541 tatttgtttt gagtcttgtg tttagtctag cattgttacc gatcacattc gtattcataa
    15601 ctttactatt aggtgcctat tttctacttt tgtcactact cactttgctg actttattaa
    15661 aacataaaaa tggatttcta attgtgatgc cctttctttt attttccatt cactttgctt
    15721 atggctttgg gacgattgta ggtttaatta gaggatttaa atggaagaag gagtacaagg
    15781 gaacaataat ttatttggat aaaataagcc aaataaatca aaatatgcta taataacaat
    15841 atagtaaaac tcttttaagg aggagtagat ttctatgaat aaaaaactaa cagattatgt
    15901 gattgatctg gtggaaattt taaataaaca acaaaagcag gttttctggg gaatatttga
    15961 tattttcagt atggtggttt ccataattgt atcttatatt ttattttatg ggctgattaa
    16021 tccagcacct gttgactaca ttatctatac gagtttggcc ttcttgttct atcaattgat
    16081 gattggtttt tgggggttga acgcgagcat tagtcgttac agcaagatta cggatttcat
    16141 gaaaatcttt tttggtgtga ctgctagcag tgtcttgtca tatagtatct gttatgcctt
    16201 cttgccactc ttctccatcc gtttcatcat tctctttatc ttgttgagta ccttcttgat
    16261 tttattgcca cggattactt ggcagttaat ctactccaga cgcaaaaaag gtagtggtga
    16321 tggagaacac cgtcggacct tcttgattgg tgccggtgat ggtggggctc tctttatgga
    16381 tagttaccaa catccaacca gtgaattaga actggtcggt attttggata aggattctaa
    16441 gaaaaagggt caaaaacttg gtggtattcc tgttttgggc tcttatgaca atctgcctga
    16501 attagccaaa cgccatcaaa tcgagcgtgt catcgttgcg attccgtcgc tggatccgtc
    16561 agaatatgag cgtatcttgc agatgtgtaa taagctgggt gtcaaatgtt acaagatgcc
    16621 taaggttgaa actgttgttc agggccttca ccaagcaggt actggcttcc aaaaaattga
    16681 tattacggac cttttgggtc gtcaggaaat ccgtcttgac gaatcgcgtc tgggtgcaga
    16741 actgacaggt aagaccatct tagtcacagg agctggaggt tcaatcggtt ctgaaatctg
    16801 tcgtcaagtt agtcgcttca atcctgaacg cattgtcttg ctcggtcatg gggaaaactc
    16861 aatctacctt gtttatcatg aattgattcg taagttccaa gggattgatt atgtacctgt
    16921 gattgcggac attcaagact atgatcgttt gttgcaagtc tttgagcagt acaaacctgc
    16981 tattgtttat catgcggcag cccacaagca tgttcctatg atggagcgca atccaaaaga
    17041 agccttcaaa aacaatatcc gtggaactta caatgttgct agagccgttg atgaagccaa
    17101 ggtgcctaag atggttatga tttcgacaga taaggcagtt aatccaccaa atgttatggg
    17161 agcaaccaag cgcgtggcgg agttgattgt cactggcttt aaccaacgta gccaatcaac
    17221 ctactgtgca gttcgttttg ggaatgttct tggtagccgt ggtagtgtca ttccagtctt
    17281 tgaacgtcag attgctgaag gtgggcctgt aacggtgaca gacttccgca tgacccgtta
    17341 ctttatgacc attccagaag ctagtcgtct ggttatccat gctggtgctt atgccaaaga
    17401 tggggaagtc tttatccttg atatgggcaa accagtcaag atttatgact tggccaagaa
    17461 gatggtgctt ctaagtggcc acactgagag tgaaattcca atcgttgaag ttggaatccg
    17521 cccaggtgaa aaactctacg aagaactctt ggtatcaacc gaactcgttg acaatcaagt
    17581 tatggataag attttcgttg gtaaggttaa tgtcatgcct ttagaatcca tcaatcaaaa
    17641 gattggagag ttccgcactc tcagtggaga tgagttgaag caagctatta tcgcctttgc
    17701 taatcaaaca acccacattg aataaaaaag aaaaacgcat attatcaagt taaacaacct
    17761 tggtaatatg cgttttatta tgtagagact tatactcttc gaaaatctct tcaaatcacg
    17821 tcaacgtcgc cttgccgtat atggttactg acttcgtcag ttccatctac aaccttaaaa
    17881 cagtgttttg agctgacttc gtcagttcca tctacaatct taaaacagtg ttttgagcag
    17941 cccgcagcta gtttcctagt ttgctctttg attttcattg agtattactt cattttcttc
    18001 tgaaatggag ttgttaccca gtctatgcta ttgaaaatac gccaaaactt ctaagggttt
    18061 gtgagcgata taatcaggtt gatagtttag tagatctgct tgctctccaa atccccaagt
    18121 gacggccaat ttctgaatac ctgtttctcg agctcccagc atatcaaact tggtatctcc
    18181 gatgatgatg gcttgttctg gtgctagttg atgtgtctgt aaggcttggt gaatgacatc
    18241 tgccttatgg ggtgcttcag ggctagaacc ataaatacca tcaaagaaat gatggatttc
    18301 caagtttttg gccatgtctt gagcagtaga tgtattcttt gtcgtggtga tgtagagtgg
    18361 ataactgctc gataactcct caagcaagtc tataatctga ggaaagagtt gagcttcata
    18421 gatgcctttt gccttatagt aagaacgata tatctgcatg gcttcagaaa tttggtcttt
    18481 ggacaggcag gtcgcaaaac tactttcgag aggtggtccc ataaaaccac gaatagtttt
    18541 ggcatcaggg ctaggcaccc ccagctcttt aaaggtatag gtaaaggcat tgtgaatccc
    18601 gatagaacta tcaacgaggg ttccatccaa atcgaaaaaa atcgctgtga tagaggtcat
    18661 ggtttctcct atttgataag cttattctcc gaaaatctct ttttggaggc gacgaccagt
    18721 aggggtggta gcgagtccac cttcagctgt ttcacgaaag gcagttggca tgcttgctcc
    18781 tacttggtac atggcatcga tcacttcatc cacagggatt ttagattcga tacctgccaa
    18841 ggccatgtct gctgcgatga aagcaaagct agctcccatg gcattacgtt tgacacaggg
    18901 aacttcgacc aaacctgcaa cagggtcaca gatgaggcct agcatatttt taatgacaaa
    18961 ggcaatagct tgactggcct gataaggtgt tccacctgca gccagagtca aggcggcagc
    19021 actcatagca gaggctgaac caacttcagc ttgacaccca ccctcagcac ctgagatgga
    19081 ggcattgttt gcgatgacta gtccaaaggc accagcagca aagaggaaat ccaattgttg
    19141 ctcgtggctg aggtctaatt tttcaatagc agcagtgaga acggatggca gacagccagc
    19201 acttccagcg gttggagtgg cacagaccaa gcccattttg gcattgtgtt cattgactgc
    19261 gatggcattt cgggcagccg agagaatcgt ataatctgac agagtttttc cgttttcgat
    19321 gtagtgatcc aatttggcag catctccacc tgtcaggcca ctacgagatt tattttcatt
    19381 gaggccaagt tggacagagg ctttcataac ttccagattg cgttccatga gaaggaagac
    19441 ttcttcacgt tcgcgaccgg tcaattcaaa ctctgttgta atcatgagtt ctgcgacatt
    19501 tccttgaaag tccagatctg cttgctcgac caattctttg atagaataaa acatgcttcc
    19561 tcctatttaa agaaattgac attgtggaga tgagggattt ttcgaatttc ttcgatagcc
    19621 tcatcacagt tgcgactgtc aacttcgata atcataatgg ctttttcacc agctttttca
    19681 cgagtgacat tcatctgggc gatattgata ccatagcggg aaagcgcctc tgtaacaagg
    19741 gcaatcatac ctggaatatc ttgatgaacg atgatgatag tcggtgtatt catattgaga
    19801 gagacggcaa aaccattgag ttcggttacc tgaatatttc ctccaccgat agaaatacca
    19861 gtcacgctga tggtcttgtg ggcattttta acagtaattt tagtggtgtt agggtgaggg
    19921 gcattgctgt ctttctgaat ggtccagaca atcttgatac cacgcttgtg ggcaatttcc
    19981 agactatttg gaatttcagg atcatctgta tccattccta aaatacctgc aacaagggct
    20041 aggtctgttc cgtgaccacg ataggtcttg gcaaatgagt taaaaagttg gaattcaact
    20101 tctgtcggag tatcatcaaa aatggaagag acaatcttcc caatacgaac agcaccagcg
    20161 gtatggctac tagatgggcc aatcataact ggtccgatga tatcaaagac agattgaaaa
    20221 cgaagtgatt tcatcagttt ccccttataa aaattcttat ctctattata tcaaagaatg
    20281 aggggcttgg ctttaattgt ggatgaaaac ctttctaata cctcaaatag cataaaaata
    20341 gtatctttta tgacaaaaaa caccttattt agggaaataa aaaataattt tgtaatattt
    20401 ctacataaaa gtgtcaagaa acggtaatat ttaaagggta tgatagaact atagaaagaa
    20461 ggagaatttt cgaatatgaa atcaataact aaaaagatta aagcaactct tgcaggagta
    20521 gctgccttgt ttgcagtatt tgctccatca tttgtatctg ctcaagaatc atcaacttac
    20581 actgttaaag aaggtgatac actttcagaa atcgctgaaa ctcacaacac aacagttgaa
    20641 aaattggcag aaaacaacca cattgataac attcatttga tttatgttga tcaagagttg
    20701 gttatcgatg gccctgtagc gcctgttgca acaccagcgc cagctactta tgcggcacca
    20761 gccgctcaag atgaaactgt ttcagctcca gtggcagaaa ctccagtagt aagtgaaaca
    20821 gttgtttcaa ctgtaagcgg atctgaagca gaagccaaag aatggatcgc tcaaaaagaa
    20881 tcaggtggta gctatacagc tacaaatgga cgttatatcg gacgttacca attaacagat
    20941 tcatacctga acggtgacta ctcagctgaa aaccaagaac gtgtagcaga tgcctacgtt
    21001 gcaggacgtt acggttcatg gacagctgct aaaaacttct ggcttaacaa tggctggtat
    21061 taagaactaa cgaacaaata atatgtaaag agtcgaggaa atccctcggc ttttttatct
    21121 ttccttcgct tggtaataga tctctacttc ttttttgaga tgagacagca tagaagtttc
    21181 ctcggtcagc tctaggagtg agaacccttt ttggataagt ttcgcattat ccctacaaat
    21241 cccaatgcgg acatagcaga tagccagcct atcgtagctt ttcttattct tggcgtcctt
    21301 cagtaaagtg tagcagattt gcttacacat gtttttatct tgattgtata gatagagtgt
    21361 ggaaaggttt aatagaattg tcattcgcaa gtcatataaa tgttgatagt ttttatagac
    21421 ttctaagcgt tgcaagattt tctcggatta ttgacaaata aacggacatt ctgatagacg
    21481 attgtcctag cggcttagtg taaactttac aaatttggct tgtaattttt ttataaaatt
    21541 cactttagtt acttgacagt tattatattt tcgctcataa tatagataaa aggatgggat
    21601 agagtttaaa aatttgaaag cgctatccat aatcataacg cataattttc tccttttcgt
    21661 gaaaaaagtt aacgtaattt tgaaatgagc ttaataagag gtactatgta ggtagaaaat
    21721 aaagatagga gaaaaagtat gaataaaaaa atattttgta ttctagtatg tattatatca
    21781 ttgattagtc tagctataat ctttccatgg ggctggtcga tataatgtaa gggagcttga
    21841 gttgttagtg gaggataaaa tgttaagagt aatagtagtt attcaatctt tagtaataat
    21901 actgcttgct gttgctttat tattatctcg gaaaaacttt gattcgttaa atgttgttct
    21961 tataatgatg atcgtatcac aattgttgtt attagtatat ttgataaaat cagggaatca
    22021 gtgattagct gttatttgaa ttaagtaaac tgttaagctt caagcagtaa ctggttttaa
    22081 atatttaaaa taagataaag gaaggaagtc taatttaggt aactaaacaa agcctgcgat
    22141 cacttgttag gaaaccatcc taagcatgct taataaaaaa ggagaaaata aatggaactt
    22201 gtattaccaa ataattatgt tgtgattgat gaagaagaga tgatgtacct tgatgggggg
    22261 gctatatata tacccaggtg ggcaattaca ggagccatta ctggtgcagc atatgcagca
    22321 ttagcagcag gaggtggagg ccttcaacta gttcttgcat cttatggatt acgctccgca
    22381 ctggtagctg ggattgttaa aggtttagga gtattaggaa ttcatattgg aaatgctttt
    22441 gcaaatactg ttattagaag tattgcatct gctggaattg gtgctggagc tgattggatt
    22501 tttaccaata ttattgatgg ctgggatggg cgacgtgata atcaattgag aataggttaa
    22561 taatcttatg ttgattgttt taatttcagt tattgttgca ttcctgtatc ataaaattac
    22621 agagtatgtc aacaacagga aaattgatat tgttattttt ctatcattgc tgatttctca
    22681 ttttatttgg aattactatt ttttaccaat tgaaatattg atagcaatca gtggagcaaa
    22741 tttattatta agttttttaa aaaaattaca gattaaataa tattattcca tatgacatat
    22801 caactaggtc attagatttt attgaagata taaattaaaa acgaggttgg gaaaaaactc
    22861 aatttgaaag tgagattgag taaatctttc tatctatata acgtatatca tcaatatttt
    22921 tgaacacctg ataatatgca cttttcttat tttaaagatt ttttgccttt cttcatttct
    22981 tgaatgaatt ggagagatga ctttatttag gtgtttgaca ttactataga taggatttag
    23041 cagtactaat atgaactcat attataggtg tagacttaaa ttttggaagc aagctaaagg
    23101 atatcttatc taggtaacta agtgctataa caagatatat tggtggagtt agtatggcaa
    23161 ctattactaa tgctcttaat attgcggcta ctgttgctga agtcttctca ttaggaggag
    23221 ccattgcata tggtttagat atcgtagacg gtaaatttga tgggtattta tgggcgtaaa
    23281 actatagcta tgaaatattt ttttgcagga attggtgaaa ttcatttttt gttattttta
    23341 ttatatctaa gcatgtctgc tagtccaatt attggactag tgattggata tactaaaata
    23401 aatctaataa attctattat tatagctctt ggtatgatat tggcattaat tttggtatta
    23461 tcaagagtgt atagaaaata tttttataga gacgatgatg actaaagttt ttatcaataa
    23521 tttgggctcc ttgtcaactg tagtgggttg aagaaaagct aacgtctggg gaaggggtta
    23581 aagctttgct ttatcaaata ttgacttaca gagttgctct attgtattga tgtattctta
    23641 gtaaataata tggtgttttg aatgaaagat gatcagaaat atttattagc gggactttat
    23701 tcgcttctag ttgcaatatt ttattttcca ttgattgagt ccaaggggat ttttgtaagt
    23761 atattgatgg cggttttact tttatattta atatacttca ttgcaacagt cattcatatt
    23821 gtgataatta agtttataag aaaaaaatct tttaagtatt tggttctata tccatttact
    23881 tatgatggga gttggagatt tcaacctata aacttactct actttccaga aatggtgaga
    23941 gatgtcattc cgattaattt agttcaagaa tattgccaag gacaacctta cggactgtta
    24001 aaaaagatgc tgaaaagaat tcgattgtca cgagagatat ctttactcct ggctaccatt
    24061 atcgtctatt tttttacgca tagaattcta cctctttcag tatttacgtt catattttct
    24121 tacatattgc tatttgtaca atcttatttg ggtggtaata ccgcttggat tggaaataga
    24181 agattaataa tagatgatga atttgaaaaa atcttgcttt caaaaagtta tgtaaaagaa
    24241 atatcatctg cacgatactc agaatacttg acatgtgaat acaaaaacct tacaccaatc
    24301 atattgatag ctatttttga aaatttgctt gactcctact tgcttcagaa tcagagtgag
    24361 gttgacttag atatttttta taaagtttta cctttgcttt ataaagaaaa atatactatg
    24421 ggattcaatt actttgtaag tttaaattat ttactatata aggttggatt tttgggaatc
    24481 atttacgata atgaagcatt aagagatttg tcaaaacaat atttaaacaa aaatatttcg
    24541 gaattacaag atggttcttt cgagggcggt atacaagatg ctgttgcctc taaacaaata
    24601 gtagttataa atgaatttat agcttgttta aattccagat gcgtgccatc ccaatatgat
    24661 agattttttt ataaagatag accttatatt ttttccagaa agagtcctat taaggggtga
    24721 aaatttgtta catttggatt aacaagtgtc ctagggatta gaaataactc tagtatagct
    24781 agatattttt gagtaactag aaatatcatt aggctaccca tatgattgcc agaaaagatg
    24841 gctgatgaat cttatttata ctgttgcagt aggcattgtc taggataaat aagctatctt
    24901 gatgggggaa attggaataa ttttagtaga aacattaaag gattatggat aagtagcgca
    24961 ggattaggtg atgcaatgtg ctaagttggc ttggtgttag cagtagtatt atttaacaat
    25021 ggaaagtaga ctaaatgaaa aataaacgtt atttttttga cacaatttta ataattttac
    25081 tgcttataag cacgatattt tgtgtcagcc cagtatttat aaaattggac atcttaggaa
    25141 ctccctctca tgccatctta acctttgtat tggcgatacc gttattctat attttgtctc
    25201 aatgcttaca tactttgcta ttactagttt cctcaatctt ttgtaaatta agaccaattt
    25261 atttttattt tatatctgtg atcattatag gagctaggaa atactatcga attctctttc
    25321 accaactaat gggatttagt ccaggaatag cagtgtttta taaggagagt caaacaacta
    25381 agaatctgtt taaattttac tacttcttgt actttacaac actaatttca tactattttt
    25441 tctttacttt tgtgtatgac aaaccgttgc ttttgcctct tatttcattt tctattatca
    25501 tagcattagt acaaaaactt tatagaattg agaatcaaca attatttctg ttaaaatcaa
    25561 aggtactaac aatactggaa tctaagaaga attgtgagtt taatcttcag gattatcatg
    25621 aaatttggaa attgcaatca aaatctgagt tgccatgcgt ggctttatct tatatcagtt
    25681 taatcaagcc atatctttca gagagtgtgc gtgaacaaat tgatttatta gaagttaagc
    25741 gatttaaaaa aataaataat ccaatatcac tttatggtat gttggatgtt ataaaattaa
    25801 atctatattt acggcattat aatgaaaaaa ataaatatga atcaatgtta aagaaaattt
    25861 tagaggtaag accagacttt gttttaatcg agcagaatat tgatgatagt ttaaatagct
    25921 cgcaaccatt atctttatct ttagccattt cagaaatcca acttttgctt gaagtgtata
    25981 tagggatcaa acatgtttca attaggagat aaaactagaa taatatttgc cattataggg
    26041 gcaagttgca tattagtcag tatgtatctt attccactta ttaaaactga gaataaattt
    26101 tgggaaatac ttttatttat attaggtgta ttgctaattg gaattgcgtt actaagtcaa
    26161 aaaaaataaa ttttgaaata gtattagtga gttcgcaatc atttattgct agtggtttag
    26221 aactgttaag tttcaaacaa taattgattt taaaccttag gtaacctata aaaacaaata
    26281 aggtagagaa aggatatctt atctaggtag ctaagtgata aaaacacagt cgtctatcac
    26341 ttgttaggaa acgatcctaa ctatgcttaa taaaaaagga gaaaataaat ggaactcgta
    26401 ttaccaaata attatgttgc tcttgagcaa gaagagatga tgtatcttga tgggggattt
    26461 tctattctga gatggcctgt tgcaacagcc attaatatag cttttaatgg tgttttaggt
    26521 ggaggagcaa tcagtctagt tagaaattat attcgtaatt atggtttgcg gcgagttaca
    26581 agcgcaattg ctggagcagc tgcaagatat gttggggtac gagttgcaaa tagagtggca
    26641 ggatttgcac tgtctgctat taatggattt gcagcttgga tgtcaattgg cgatgctatt
    26701 acaacaatct gggccaacaa tgatgtaaat aggagagacc caaatttaaa cgccttgtgg
    26761 taactagata tgggtattaa aatggaaaaa atttttgtta ttattttttt tgtatgtcta
    26821 tttatatcat ccataacttt tttagcctat gattttgtta gcgaagaaat aaaaaagttg
    26881 attatttgga tgaatgtcgt ttttttgatt ttaatcatag caatgataat ttatccaaaa
    26941 ttaagaaaat gataaggaca ctgtaaaatt atgatacgta aactaatcat ttttttatta
    27001 atgctccctc tttttgtctt gtggctagag ttgcatttgt tagtgagtaa cttgcaattg
    27061 aatctagaaa ttccccttga ttttgtggtt agtacgagtc ttgctttctg tagtttgatt
    27121 ttatcaaaaa tagttttaga catactatac gcattgaaag atttgtacaa gaaagaagct
    27181 cttattacga tttttccttt tatttttata ggtaggaaga aagtaaatgt gaggttctcg
    27241 ccctattttt cattccatcg taaaagtttg tcgcctgatg atttaagatc taggattata
    27301 tggagtttta ttcttgaaat tgctattatt ctagtattta ttttaaaaat tccttttgca
    27361 atcatcatgc ttactacaat atttttctgg actataatgg atatcaatca tctcgttttt
    27421 aataagacgg aatttctttt taatcaaaat aaatgggaaa aagaagattc gtttgaaagc
    27481 gatttgacga aaacgttaaa ggataagata caaaaatcag agctaagtta ttctgactta
    27541 atgtctcttc agctgtatga tgcgatgaac caatccacct ttttaacgga tagtgaactt
    27601 tttgaggata ttttgaaaaa aatcgaagat tctcataaca cccttctgtg tacaggtctt
    27661 gtcgagttac tgctgtatga aatgtctatt agtaacaata acaactggtc caacaaggtt
    27721 gataaaatta ggatacacct catcagaatc aatcaattag attttttcta ttatacaagt
    27781 tggttaaggc aaaattttga tttctgtatg aatagagagt atcataaaat gaaatctcgg
    27841 aaattattac tgagtaataa aaagatagtt taagttcgtc ctatttgtaa aacaaatgaa
    27901 acaatttcaa ctaaggagga gaaaacaaat ggaacttgta ttaccaaata attatgttgt
    27961 gattgatgaa gaagaaatga tgtatcttga tgggggagct tatttaagca agcgtgcttg
    28021 tcaaggaatt tgcgtagctt tagctatgag ttcaggaact tttatagcat tagctggagc
    28081 tgcagtttta accaaaaaac taataaacta tattaaggtt ggaggtcttg gaggctggct
    28141 tattggtgca gcagcaggaa aaatagctta ctgtattgga tatggtgctc ttaatagagg
    28201 ttgtgatatt agcgggaacc cttatccttg ggatggattt atatctgcga cagtaagatg
    28261 aataatgtag ataagattcg aaaaatacat attatcgtat gttgggtgta tatattttta
    28321 tcattcaggg cgattataaa tgacacggag tattttttgc ttattttttt agcttttatc
    28381 tactcaatag tatcactacc tctatattct gtgaaaaata aaatagtatc tatctgtcta
    28441 gccataaatt cgattctgtt aatgagtttc cccattttaa tcaataagtt tttcccagaa
    28501 agttttttga cttataccgt attaataagt gtttttatcc tagagttagc aatctttcat
    28561 ttaattgggg aagattttgc tactaaattg actaacgaat ataagaaaat tagtcagttt
    28621 agaagcaagg tgtctcaatc ttcttggata aaatatttag agatttctag ttttatatta
    28681 actatatttc catctattct ttacggtaca gttgataatc gtgtattggc tcttatcttt
    28741 ttgataaaaa tttgtgtaga tactacgata aaatttttat tcatcagatt atttgacaca
    28801 agtactttaa tgaagaggag aatatttttt cttttcgcat tggatgttat agcttactta
    28861 tttttaggat atcttttagt gattcaaaaa gcaggctatt tgttttcggt tttacttctt
    28921 ttttctaatt tttcagttcc atttatcaaa gcaaaggaat acgaattatt taaaaatagc
    28981 aagtaataga aacataggtt aaatcttaga acggcttaaa atcagatatg ataaagggaa
    29041 atagtcttat ctaggtaact aagtgctaca aacacagtcg aggatcactt gttaggatta
    29101 cattttaatc atgcttaata agaatggaga attcctatgg ggattgtatt actctgaagt
    29161 ttcgaatacc ttagttctcg tgattttgag ctgttctagc tttagaatcc ttcagaatgt
    29221 aaaattttaa gcagtcaaag acttagaata gcctggaaac atttatttta tagcaattct
    29281 aggcttagaa ttgctcatat atatgtattt gagctgctcg atagttagga cagctctatt
    29341 ctgagaaatc tgagctatca atgcttcaga atagtatttc gcaaatggtt tttattgaag
    29401 aggtgattgt tttatgatag tctaaaataa aactgattta atggagtaaa tggagaatcg
    29461 tcacatgaaa catttttttg caggaattgg tgagataaaa cttgttggct acttattgta
    29521 tatatgtgta ggactagccc ttctttttca tatatatgtc ataggttcgg aactgagttt
    29581 tgtgaaaata gtgttatcta ttttgggagt tatatttgta agtatgttaa ctattgctcg
    29641 aatttatcgg acttttctat aaagaatagt ttggacttga actgtatcta aaaacagagg
    29701 ttggtcgatt atcagcctct ttcttgtcgt tgaaaagagt gagatatatt gacttttgaa
    29761 aaaaatgtca taattgagtt gggataaacc taaaagtaat atagtagatt gaatctggaa
    29821 tagtccgtta tgactgttaa aatatttcta gaaattaatt tgactttcct aatcgatttg
    29881 ttcacatctt gtttcaatct actatacttt ctcgttaaac cgttcggcaa ttcatggtga
    29941 catggacaca tagtagtaag cacactatgt ggcttggcag agctaaaaac tgttcccttg
    30001 cgataagcct aataagcaca acatagggag ttagagaagc cgactctaat caaccacttt
    30061 gggcagtagt gagaactgcc ccgtgctttt ttattttgag aaaatatgga gtttgtcgtt
    30121 gaaattactt gattgtattt tggactatca agaaagattc aatggaaaaa catgtcaagt
    30181 atcaacgaat tataagtatt tagagatttt caaagtgaat ttttgcttga ctgatttaca
    30241 tcatttattt gacttataca aaatcacacg agattatgct agtcaaacaa aacctgctat
    30301 tcaagctggt gtttttattt tagaagattt tagaaatatc ctatgtacaa tgatgtaatc
    30361 gaaaggatat ctttatatga gtttatcggc gatatcttct atatctaagc tagcaagttg
    30421 ttgcatcgta gctagggatt tatctaaaaa tactatgaaa ttggacgtca tattttttga
    30481 ggataaaaat aaaagatccg cagttttagg tttacgaaga gacaaaagcg gagtatttaa
    30541 atcagttact ctacatttta caagcgctaa gaaatatgct aaagttcgta aaacagatgt
    30601 gaaagaaatg aaatggctat aaagattgtc cgcaggctta agcttgcgtt ttttgttgtt
    30661 taacgaaatt aaaaaacaag ctctctcatc ggaaatgttt ttataggaat gaaggaagat
    30721 gatgctatgt ttaaaaagag aatcgaaaag ggcaaaagta gtatctttat ctattttttg
    30781 gagtagaagc ttatgatata gaaatttgta ataaaaatgt aatataaaac atttgacaaa
    30841 tatttacggg gggagtatac ttaatataag tatagtctaa aaatgactat cagaaaagag
    30901 gtaaatttag atgaataaga aaaaaatgat tttaacaagt ctagccagcg tcgctatctt
    30961 aggggctggt tttgttgcgt ctcagcctac tgttgtaaga gcagaagaag ctcccgtagc
    31021 taagcagtct caagctgaga gagactatga tgcagcaatg aaaaaatctg aagctgctaa
    31081 gaaagaatac gaagaagcta agaaagattt agaagaagca aaagctgctc agaaaaaata
    31141 tgaagatgat caaaagaaaa ctgaagagaa agcaaagctt gttcaaaaag cggatgaaga
    31201 gcgtcaaaaa gcgaatgtgg cagttcaaaa ggcgtattta aaactccgag aagcacaaga
    31261 acaattgaac aaaagtccaa acaataagaa aaatgccgct caacagaaat taaaagatgc
    31321 attagctcat attgatgagg taacattaaa acaaaaagag gcggaagcga atttcaataa
    31381 ggaacaagca aaagtagttc ctgaagcaga taagttagct gagactaaga aaaaagcaga
    31441 acaggctgaa aaaaaagaac cagaacttgc taaaaaagta gcagaagcta aagcaaaagc
    31501 agaagaagct gagaaaaaag ctgttgaagc caaacaaaaa gtggatgctg aaaaatatgc
    31561 tcttgaagct aaaatcgctg agttggaata tgaagttcag ggactagaaa aagagctcaa
    31621 agagattgat gagtctgact cagaagatta tattaaagaa ggtctccgtg ctcctcttca
    31681 atctaaattg gatgccaaaa aagctaaact atcaaaactt gaagagttga gtgataagat
    31741 tgatgagtta gacgctgaaa ttgcaaaact tgaaaaagat gtagaagatt tcaaaaactc
    31801 agacggtgag caagctgaac aatatcttgt tgcagctaaa aaagacttag atgctaaaaa
    31861 agctgaatta gaaaatactg aagctgacct taagaaagca gttgatgagc cagaaactcc
    31921 agctccggct ccggctccta aaccagcccc agctcc
//
LOCUS       DBERPV010000022        31451 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.22, whole genome shotgun sequence.
ACCESSION   DBERPV010000022 DBERPV010000000
VERSION     DBERPV010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 31451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31451
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.22"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            5..75
                     /locus_tag="ACL8C7_001290"
     tRNA            5..75
                     /locus_tag="ACL8C7_001290"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37..39,aa:Gly,seq:tcc)
     gene            110..183
                     /locus_tag="ACL8C7_001291"
     tRNA            110..183
                     /locus_tag="ACL8C7_001291"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:144..146,aa:Ile,seq:gat)
     gene            266..355
                     /locus_tag="ACL8C7_001292"
     tRNA            266..355
                     /locus_tag="ACL8C7_001292"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:302..304,aa:Ser,seq:tga)
     gene            366..439
                     /locus_tag="ACL8C7_001293"
     tRNA            366..439
                     /locus_tag="ACL8C7_001293"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:400..402,aa:Met,seq:cat)
     gene            443..515
                     /locus_tag="ACL8C7_001294"
     tRNA            443..515
                     /locus_tag="ACL8C7_001294"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:476..478,aa:Phe,seq:gaa)
     gene            528..608
                     /locus_tag="ACL8C7_001295"
     tRNA            528..608
                     /locus_tag="ACL8C7_001295"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:562..564,aa:Tyr,seq:gta)
     gene            613..683
                     /locus_tag="ACL8C7_001296"
     tRNA            613..683
                     /locus_tag="ACL8C7_001296"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:645..647,aa:Trp,seq:cca)
     gene            698..770
                     /locus_tag="ACL8C7_001297"
     tRNA            698..770
                     /locus_tag="ACL8C7_001297"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:731..733,aa:His,seq:gtg)
     gene            781..852
                     /locus_tag="ACL8C7_001298"
     tRNA            781..852
                     /locus_tag="ACL8C7_001298"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:813..815,aa:Gln,seq:ttg)
     gene            862..945
                     /locus_tag="ACL8C7_001299"
     tRNA            862..945
                     /locus_tag="ACL8C7_001299"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:896..898,aa:Leu,seq:caa)
     gene            1052..2329
                     /locus_tag="ACL8C7_001300"
     CDS             1052..2329
                     /locus_tag="ACL8C7_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HGS1395493.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     MKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIISPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETMIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2405..3889
                     /gene="thrC"
                     /locus_tag="ACL8C7_001301"
     CDS             2405..3889
                     /gene="thrC"
                     /locus_tag="ACL8C7_001301"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004795 - threonine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HGS1395494.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIALLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNMQGQYKLTDFDAEILELFAAEYATEEETAAEIKRVYELDS
                     YIEDPHTAVASAVYRKYQAVTDDATKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLETAPVRHKTTVAAADMQAAVEAYLGL"
     gene            3950..5230
                     /locus_tag="ACL8C7_001302"
     CDS             3950..5230
                     /locus_tag="ACL8C7_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGS1395495.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            5234..5854
                     /locus_tag="ACL8C7_001303"
     CDS             5234..5854
                     /locus_tag="ACL8C7_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGS1395496.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            6020..7162
                     /locus_tag="ACL8C7_001304"
     CDS             6020..7162
                     /locus_tag="ACL8C7_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGS1395497.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETSSAVAEEAPQETTPGEKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPESSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            7482..7906
                     /locus_tag="ACL8C7_001305"
                     /pseudo
     CDS             7482..7906
                     /locus_tag="ACL8C7_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
     gene            7917..8275
                     /locus_tag="ACL8C7_001306"
                     /pseudo
     CDS             7917..8275
                     /locus_tag="ACL8C7_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
     gene            8382..9000
                     /locus_tag="ACL8C7_001307"
                     /pseudo
     CDS             8382..9000
                     /locus_tag="ACL8C7_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(9028..9885)
                     /locus_tag="ACL8C7_001308"
     CDS             complement(9028..9885)
                     /locus_tag="ACL8C7_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HGS1395498.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            10015..11157
                     /gene="tgt"
                     /locus_tag="ACL8C7_001309"
     CDS             10015..11157
                     /gene="tgt"
                     /locus_tag="ACL8C7_001309"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HGS1395499.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            11258..13075
                     /locus_tag="ACL8C7_001310"
     CDS             11258..13075
                     /locus_tag="ACL8C7_001310"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HGS1395500.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAVAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13228..14379
                     /gene="nagA"
                     /locus_tag="ACL8C7_001311"
     CDS             13228..14379
                     /gene="nagA"
                     /locus_tag="ACL8C7_001311"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HGS1395501.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPYTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14542..15600
                     /locus_tag="ACL8C7_001312"
     CDS             14542..15600
                     /locus_tag="ACL8C7_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HGS1395502.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15751..16116
                     /locus_tag="ACL8C7_001313"
     CDS             15751..16116
                     /locus_tag="ACL8C7_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HGS1395503.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16192..17133
                     /gene="comGA"
                     /locus_tag="ACL8C7_001314"
     CDS             16192..17133
                     /gene="comGA"
                     /locus_tag="ACL8C7_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HGS1395504.1"
                     /translation="MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKIASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEEFAVVLQGVCYQRLIGGGGIVDFAS
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17081..18097
                     /gene="comGB"
                     /locus_tag="ACL8C7_001315"
     CDS             17081..18097
                     /gene="comGB"
                     /locus_tag="ACL8C7_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HGS1395505.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVTQMRVGLSQGKSFSEMMESLGCSSAIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLFFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
                     LGMIVFVSVGVLLALTFYKRSSKMRVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLRPMYQNM
                     EVNF"
     gene            18099..18425
                     /gene="comGC"
                     /locus_tag="ACL8C7_001316"
     CDS             18099..18425
                     /gene="comGC"
                     /locus_tag="ACL8C7_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HGS1395506.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKDDGRITEEQVKAYKEYNDKNGGA
                     NRKVND"
     gene            18418..18822
                     /gene="comGD"
                     /locus_tag="ACL8C7_001317"
     CDS             18418..18822
                     /gene="comGD"
                     /locus_tag="ACL8C7_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HGS1395507.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTISNGSQKLPVPKGIQVPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18785..19087
                     /gene="comGE"
                     /locus_tag="ACL8C7_001318"
     CDS             18785..19087
                     /gene="comGE"
                     /locus_tag="ACL8C7_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGE"
                     /protein_id="HGS1395508.1"
                     /translation="MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQE
                     EAKILQKEEVLRVAKMALQTGQNQVNINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            19050..19511
                     /gene="comGF"
                     /locus_tag="ACL8C7_001319"
     CDS             19050..19511
                     /gene="comGF"
                     /locus_tag="ACL8C7_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HGS1395509.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALLVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWILFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            19489..19902
                     /gene="comGG"
                     /locus_tag="ACL8C7_001320"
     CDS             19489..19902
                     /gene="comGG"
                     /locus_tag="ACL8C7_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HGS1395510.1"
                     /translation="MWKKKKVKAGVLLYAVTMAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTDKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            20039..20633
                     /locus_tag="ACL8C7_001321"
                     /pseudo
     CDS             20039..20633
                     /locus_tag="ACL8C7_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            20694..21647
                     /locus_tag="ACL8C7_001322"
     CDS             20694..21647
                     /locus_tag="ACL8C7_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGS1395511.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELEQVKDNNQTLKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSNLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21698..22888
                     /locus_tag="ACL8C7_001323"
     CDS             21698..22888
                     /locus_tag="ACL8C7_001323"
                     /EC_number="2.7.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008776 - acetate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006085 - acetyl-CoA biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HGS1395512.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            22889..23020
                     /locus_tag="ACL8C7_001324"
     CDS             22889..23020
                     /locus_tag="ACL8C7_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395513.1"
                     /translation="MKLKKYSIQGVGKVIFPASFSDEIVQNLAMIGFFEKYGIIVVI"
     gene            23037..23408
                     /gene="rnpA"
                     /locus_tag="ACL8C7_001325"
     CDS             23037..23408
                     /gene="rnpA"
                     /locus_tag="ACL8C7_001325"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HGS1395514.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            23383..24207
                     /locus_tag="ACL8C7_001326"
     CDS             23383..24207
                     /locus_tag="ACL8C7_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HGS1395515.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            24226..25212
                     /gene="jag"
                     /locus_tag="ACL8C7_001327"
     CDS             24226..25212
                     /gene="jag"
                     /locus_tag="ACL8C7_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HGS1395516.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            25263..25886
                     /locus_tag="ACL8C7_001328"
     CDS             25263..25886
                     /locus_tag="ACL8C7_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HI_0552 family protein"
                     /protein_id="HGS1395517.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQTKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            26017..27474
                     /locus_tag="ACL8C7_001329"
     CDS             26017..27474
                     /locus_tag="ACL8C7_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGS1395518.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFIFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27497..27778
                     /locus_tag="ACL8C7_001330"
     CDS             27497..27778
                     /locus_tag="ACL8C7_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS1395519.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            27855..28340
                     /locus_tag="ACL8C7_001331"
     CDS             27855..28340
                     /locus_tag="ACL8C7_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002267837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGS1395520.1"
                     /translation="MNLKQALIDNDSIRLGLEANDWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            28357..29022
                     /locus_tag="ACL8C7_001332"
     CDS             28357..29022
                     /locus_tag="ACL8C7_001332"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HGS1395521.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAVDPAGAARAFKDEIKR
                     IWG"
     gene            29026..29889
                     /locus_tag="ACL8C7_001333"
     CDS             29026..29889
                     /locus_tag="ACL8C7_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HGS1395522.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFIEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDSVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            29891..30595
                     /locus_tag="ACL8C7_001334"
     CDS             29891..30595
                     /locus_tag="ACL8C7_001334"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HGS1395523.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVTYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30772..>31451
                     /locus_tag="ACL8C7_001335"
     CDS             30772..>31451
                     /locus_tag="ACL8C7_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HGS1395524.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALVDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEIT"
BASE COUNT         9396 a         5530 c         7247 g         9278 t
ORIGIN      
        1 tttagcgggt gtagtttagt ggtaaaacta cagccttcca agctgttgtc gcgagttcga
       61 ttctcgtcac ccgctttgaa ctttgttctt tgtaccaagt ttttgacttg ggcgcgtagc
      121 tcaggtggtt agagcgcacg cctgataagc gtgaggtcgg tggttcgagt ccactcgtgc
      181 ccatagtgtt tagtccatta ctaggggatt ggaatattat ctgttcacta agaggacacg
      241 ggcttgttcc cgtataaact attttggagg attacccaag tccggctgaa gggaacggtc
      301 ttgaaaaccg tcaggcgtgt aaaagcgtgc gtgggttcga atcccacatc ctccttttat
      361 attaacgcgg gatggagcag ctcggtagct cgtcgggctc ataacccgaa ggtcgtaggt
      421 tcaaatcctg ctcccgcaat aaggctcggt agctcagttg gtagagcaat ggattgaagc
      481 tccatgtgtc ggcggttcga ttccgtctcg cgccatttat atattttgga agggtagcga
      541 agaggctaaa cgcggcggac tgtaaatccg ctccttcggg ttcgggggtt cgaatccctc
      601 cccttccatt ttacgggcat agtttaaagg tagaactaag gtctccaaaa ccttcagtgt
      661 gggttcaatt cctactgccc gtgttaatag aattatggcg ggtgtggtga agtggttaac
      721 acaccagatt gtggctctgg catgcgtggg ttcgatcccc atcactcgcc tattttatat
      781 tggggtatag ccaagcggta aggcaaggga ctttgactcc ctcatgcgtt ggttcgaatc
      841 cagctacccc agttactatt tgccggcgtg gcggaattgg cagacgcgct ggactcaaaa
      901 tccagtgtcc gcaaggacgt gccggttcga ccccggccgc cggtatagta tagtgttagg
      961 aacgttgtta ttcttcgttc cttttttata ttatttttgg tataattata gttattcaaa
     1021 ttttatttag attaagaaag tgtaggggag tatgtcttgt tctatcgatt tattaaaaca
     1081 tcggtatttg aaaaatatta aagaaaatcc tgaattgttt gtcggaattg agttggagta
     1141 tcctgttgca agtttagaag gggatgctac agatgttgaa gttatgaagg atctatttca
     1201 ttatttagtt tctactttgg atctcaccgt agcaaaggta gatgattttg gcaatctgat
     1261 ccagttagta gatccgataa gtcaggatgc tattttattt gaagtttcct atacaacgat
     1321 tgagtttgca tttggtaagg ctgaaacgat tcaagaggtc gaaaatcgtt tcaataatta
     1381 tatgaatgta attcagagaa agttagctga atcaaatcat gctattgttg gctgtggtat
     1441 ccatcccaac tgggataaaa atgagaattg tccagtggct tatccacgct atcagatgtt
     1501 gatggattat ttgaatttga gtagaaatat tattaaatca gatttacatc atttccctga
     1561 atatggtact tttatctgtg ggagccaggt tcagctggat atttcaaaaa ccaactactt
     1621 acgggtgatt aatgctttta ctcaaattga agcggctaag gcttatttat ttgcaaactc
     1681 tgagttttcg ggtgcggatt gggatacgaa aatttcaagg gatattttct gggaagaatc
     1741 tatgcatggt atctatccag agaatgttgg ggtcaatgct agactcctta atgatgaagc
     1801 tgattttttt gactatctaa atcattctgc gatttttact gcggaacgtg atgggcagac
     1861 ctattatttt tatcctattc aggctgggga ctatttggct acgcctgaaa tccaagcatt
     1921 tgctctgaat ggggatgagg ttattatttc ccctcaagag aaggattttg aaactcatcg
     1981 tagttaccaa taccaagatt taacgactcg aggaacagtt gagtttcgta gtgtgtgtac
     2041 acagccactt gataggactt ttgcttctgc agcttttcac ttgggattat tggttaattt
     2101 agacaagtta gaagcttact tagaaacagc acctttcttt aaagtatttg gttatgatta
     2161 caagtcttta aggagacaat tttctaagaa aaatcttaca gatgaggaag aaactatgat
     2221 tattgaattt tccaaagact tactcctact agctgaggag ggactagtgg tgagaaataa
     2281 ggaagaaatg acctatttac agcctttgag agaagaattg agcctataat ttctcttata
     2341 aagggagaat tttctgaaaa atcatgatat aatggacgag actatagata aaggatagag
     2401 agtaatgaca ttagtttatc aatcaacgcg tgatgccaac aatacagtaa ctgccagcca
     2461 agcaattttg caaggtttgg cgacggacgg cggtttgttt acaccggtta cttatccaaa
     2521 ggtagatttg gactttgaca aattgaaaga tgcttcttac caggaagttg ctaagctagt
     2581 tttgtcagca tttttagatg actttacagc tgaggagttg gactactgta tcaacaatgc
     2641 ctacgatagc aaatttgata ctccagctat tgcactatta gtgaaattag atgggcaata
     2701 caatttggaa cttttccatg gttcaacgat tgcctttaag gatatggcct tgtctatttt
     2761 gccatacttt atgacgactg ctgctaagaa acatggtttg gagaacaaga ttgttatatt
     2821 gacagcgaca tctggtgaca cggggaaagc tgctatggcg gggtttgcgg atgtgcctgg
     2881 tactgagatt atcgtctttt atccaaagga tggtgtcagc aagattcaag agttacaaat
     2941 gaccactcag actggcgaca atactcatgt tattgctatt gatggtaact ttgacgatgc
     3001 gcaaacaaat gtgaagcaca tgtttaacga tgtggctctt cgtgaaaaat tgactaccaa
     3061 caagttgcaa ttttcatcag ctaactctat gaacattggt cgtctggtgc cacaaattgt
     3121 ttattatgtt tatgcttacg ctcaattggt taagactggt gaaattgtag ctggtgaaaa
     3181 ggttaacttc acagtaccaa caggaaactt tggaaatatc ttggctgcct tttatgccaa
     3241 acaaattggt ttgccagttg gtaaattgat ctgtgcttca aatgacaaca atgttttgac
     3301 agacttcttt aaaacacgtg tctatgacaa aaaacgtgag tttaaggtaa caaccagccc
     3361 atctatggat atcttggtat cttcaaactt ggagcgcttg attttccatc ttttgggaaa
     3421 taatgctgaa aagacagctg aactcatgaa tgctttgaac atgcaaggac aatataagtt
     3481 gacagacttt gatgcagaga ttctggagct ctttgcagct gaatatgcga ctgaggaaga
     3541 aacagcggca gaaatcaagc gtgtttatga gttagattct tatattgagg atccacatac
     3601 ggcggttgcc tcagcagttt atagaaaata ccaagcggtt actgatgatg cgactaagac
     3661 agtgattgct tcaacagcta gtccctacaa gttcccagta gttgcagtag aagctgtaac
     3721 tggaaaagca ggtttaacag actttgaagc cttggctcaa ttacatgaaa tctcaggcgt
     3781 tgcagtgcca ccagcagttg atgggcttga gacagctcct gttcgtcaca agacaactgt
     3841 agcggctgct gatatgcaag cagcggttga ggcttattta ggactttaag atagagggag
     3901 taaactcggt tgggaaacca actgagtttc ttttcatcag gaggagagat tgtttaagaa
     3961 aaataaagac attcttaata ttgcattgcc agctatgggt gaaaactttt tgcagatgct
     4021 aatgggaatg gtggacagtt atttggttgc tcatttagga ttgatagcta tttcaggggt
     4081 ttcagtagct ggtaatatta tcaccattta tcaggcgatt ttcatcgctc tgggagctgc
     4141 tatttccagt gttatttcaa aaagcatagg gcagaaagac cagtcgaagt tggcctatca
     4201 tgtgactgag gcgttgaaga ttaccttact attaagtttc cttttaggat ttttgtccat
     4261 cttcgctggg aaagagatga taggactttt ggggacggag agggatgtag ctgagagtgg
     4321 tggactgtat ctatctttgg taggcggatc gattgttctc ttaggtttaa tgactagtct
     4381 gggagccttg attcgtgcaa cgcataatcc acgtctgcct ctctatgtta gttttttatc
     4441 caatgccttg aatattcttt tttcaagtct agctattttt gttctggata tggggatagc
     4501 tggtgttgct tgggggacaa ttctgtctcg tttggttggt cttgtgattt tgtggtcaca
     4561 attaaaactg ccttatggga agccaacttt tggtttagat aaggaactgt tgaccttggc
     4621 tttaccagca gctggagagc gacttatgat gagggctgga gatgtagtga tcattgcctt
     4681 ggtcgtttct tttgggacgg aggcagttgc tgggaatgca atcggagaag tcttgaccca
     4741 gtttaactat atgcctgcct ttggcgtcgc tacggcaacg gtcatgctgt tggcccgagc
     4801 agttggagag gatgattgga aaagagttgc tagtttgagt aaacaaacct tttggctttc
     4861 tctgttcctc atgttgcccc tgtcctttag tatatatgtc ttgggtgtac cattaactca
     4921 tctctatacg actgattctc tagcggtgga ggctagtgtt ctagtgacac tgttttcact
     4981 acttgggacc cctatgacga caggaacagt catctatacg gcagtctggc agggattagg
     5041 aaatgcacgc ctcccttttt atgcgacaag tataggcatg tggtgtatcc gcattgggac
     5101 aggatatctg atggggattg tgcttggttg gggcttgcct ggtatttggg cagggtctct
     5161 cttggataat ggttttcgct ggttatttct acgctatcgt taccagcgct atatgagctt
     5221 gaaaggatag gaaatgcaaa aaacagcttt tatttgggat ttagacggga ctttattgga
     5281 ctcttacgaa gcgattttat cagggattga ggagactttt gctcagtttt ctattcctta
     5341 tgataaggag aaggtgagag agtttatctt caagtattcg gtgcaaaatt tgcttgtgcg
     5401 ggtggcagaa gatagaaatc tggatgttga ggtgctaaat caggtgcgtg cccagagtct
     5461 ggctgagaaa aatgctcagg tagttttgat gccaggtgcg cgtgaggtgc tagcttgggc
     5521 agacgaatca ggaattcagc agtttatata tactcataag gggaacaacg cttttaccat
     5581 tctcaaggac ttgggggtgg aatcctattt tacagagatt ttaaccagtc agagtggctt
     5641 tgtgcggaag ccaagtccag aagcggctac ctatctgcta gataagtatc agttgaattc
     5701 tgataatact tattatatag gggatcggac tctggatgtg gaatttgccc agaatagtgg
     5761 gattcaaagt atcaactttt tagagtctac ttatgaaggg aatcacagga ttcaagcgtt
     5821 agcagatatt tcccgtattt ttgagactaa gtgataaaaa gattgtgtca gttttgtgac
     5881 agagacctaa caaactattt caagtaacct agtttgttac aaggaataga cagttctgtt
     5941 aaataggccc gagagggctt tttttctaca ttttttgtgt tatgatagac aggtactcat
     6001 ttgaaaggaa tttgaaagaa tgaagaaaag aatgttatta gcgtcaacag tagccttgtc
     6061 atttgcccca gtattggcaa ctcaagcaga agaagttctt tggactgcac gtagtgttga
     6121 gcaaatccaa aacgatttga ctaaaacgga caacaaaaca agttataccg tacagtatgg
     6181 tgataccttg agcactattg cagaagcctt gggtgtagat gtcacagtgc ttgcgaatct
     6241 gaacaaaatc actaatatgg acttgatttt cccagaaact gttttgacaa cgactgtcaa
     6301 tgaagcagaa gaagtaacag aagttgaaat ccaaacacct caagcagact ctagtgaaga
     6361 agtgacaact gcgacagcag atttgaccac taatcaagtg accgttgatg atcaaactgt
     6421 tcaggttgca gacctttctc aaccaattgc agaagctcca aaagaagtag catcaagttc
     6481 agaagttaca aagacagtga ttgcttctga agaagtggca ccatctacgg gcacttctgt
     6541 cccagaggag caaacggccg aaacaagcag tgcagttgca gaagaagctc ctcaggaaac
     6601 gactccaggt gagaagcagg aaacacaagc aagccctcaa gcagcatcag cagtggaagc
     6661 aactacaaca agttcagaag caaaagaagt agcatcatca aatggagcta cagcagcagt
     6721 ttctacttat caaccagaag agacgaaaat aatttcaaca acttacgagg ctccagctgc
     6781 gcccgattat gctggacttg cagtagcaaa atctgaaaat gcaggtcttc aaccacaaac
     6841 agctgccttt aaagaagaaa ttgctaactt gtttggcatt acatccttta gtggttatcg
     6901 tccaggagac agtggagatc acggaaaagg tttggctatc gattttatgg taccagaaag
     6961 ttcagaatta ggggataaga ttgcggaata tgctattcaa aacatggcca gccgtggcat
     7021 tagttacatc atctggaaac aacgtttcta tgctccattc gatagcaaat atgggccagc
     7081 taacacttgg aatccaatgc cagaccgtgg tagtgtgaca gaaaatcact atgaccacgt
     7141 tcacgtttca atgaatggat aaacccgact tggtaacatc attttgacga atgagatcta
     7201 gctttcgtga taggaagcga ttctcgttcg ttttttcttt gtcatactct tcgaaaatct
     7261 cttcaaacca cgtcagtttt atctgaaacc tcaaagctgt gctttgagca acctgcgact
     7321 agctttctag tttactcttt gatttttatt gagtatcaat ttgaatggaa aatggaaagt
     7381 tattatcttg taataatcca agcaacattc ttgcaatcta ttttacttta tatcacaatt
     7441 gattggtcaa ctattgataa gtcaatggat aggaggaaga aatgatagag attcaagatt
     7501 tactgtatca actccgcttg tctgagcaag cgagtacgca attgtttgaa aaaggcttgg
     7561 gattagtttg acacggtatc agattttact gtttttgctg gagcattctc cttgtaacca
     7621 aatggcggtt caggagcgtt tgaaaattga tcaggctgct ttgacacggc atttcaagat
     7681 tttggaaacg gaaggtttgg tggagcgtca tcgtaatcct gaaaatcagc gggaagtgtt
     7741 ggtagaggct gcgaagtatg ccaaggagca gttagtggtg aatccccctc tgcaacatat
     7801 caaggttaag gaagagatgg aaagtatctt aacagagttt gagagaacag aactcagccg
     7861 tttattaaat aaattggttt tgggtattga aaatatagaa atttaaggag aaatagatgt
     7921 caattatttt aacaacgatc gttgctttgg agcattttta tattttttat ttggaaagta
     7981 ttgccacgca atcagatgcg actagtcgtg tatttaatat ggaaaaggaa gaattggctc
     8041 atccgtcagt aagttcattg ttcaaaaatc aaggaattta taaggctctg ctaggagtct
     8101 ttctcttgta tgtcatttat ttctcacaga atttagaaat tgtgactatt tttgtcttat
     8161 ttgtgattgg tgctgcgact tacggctctt taacagcgga taaaaaatta ttttgaagca
     8221 aggtggatca gctattttgg ccttgattag tattttactc tttaaataca cttgaaggtt
     8281 gattctaatc tcgctaatcc tttttaatcc agaataaggg aaatatgtta tacttgtttt
     8341 taagaaaaaa gtctcattga attggttttg aggagttaga aatgaaagta ttagtgacag
     8401 gttttgagcc cttttgaggc cattaaaggt ttaccagctg aaatccatgg tgctgaggtc
     8461 cgttggctag aggtgccgac agtttttcac aaatctgctc aagtattgga agaagagatg
     8521 aatcgttatc aacctgactt tgtcctttgt attgggcaag ctggtggaag aactagtttg
     8581 acacctgaac gagtggccat taatcaagac gatgcacgta cttctgataa cgaagataat
     8641 caaccgattg accgtcccat tcgcccagat ggtgcttcgg cctactttag tagtttgccg
     8701 attaaagcga tggttcaagc tataaaaaaa gagggcttac cggcctctgt ttccaatacg
     8761 gcagggactt ttgtctgcag ccatttgatg tatcaggctc tctatttggt agaaaagaaa
     8821 ttttcatatg ttaaggcagg ttttatgcat attccttata tgatggaaca ggtggtgaac
     8881 agaccgacta ctccagctat gagtttagtg gatattcggc gagggataga agcagcaatc
     8941 ggcgctatga tagaacatgg agatcaggaa ctcaagttgg taggcggaga aactcattga
     9001 tagaaaaaag cttgagggga aaaaccttca agcttttgga cgttttcgag ccaatactgc
     9061 tcggtaaaac ataattttag tgcattggat ataaggtagg agtgaaaaac tagcaatgcc
     9121 aaaggtaatc caattgagga agtaccaagg aagaagctgt aaatctagga caaagtgctg
     9181 gaacttgtag cccttcataa aggaacggct agtttttagg attcgtcttg gtgggacctg
     9241 tcctaggtct agactataac agagaagaaa ttccacctgt gaataggcat aatactgtgg
     9301 aatatagagg atatttccta caatgatcaa gatgagactt gcaagaaagt agagtccaaa
     9361 gaccatgagg aaacgctcgg tttcaactga tgagagatct agatttggaa actcaggatg
     9421 tagggtgacg aattttttgg ctaaaaagct actataaaag aggaggtaaa tcccaagtaa
     9481 attagggata ctccataaaa agagatagaa acgtttgaga agtagggtca aaaaggtttg
     9541 agaaaagcgc tcctcatcaa agagagctag gctgtttttt acagatggct ccgttttaga
     9601 atctttcatg agtgtcagtg ttgcatagac ggaactggtc aaaagaatag tcccgataaa
     9661 ggagactagt agaggaaaga ggtaggcttg aagtatttgg ccaagtatgc tgaaaaatgg
     9721 ctgttctaaa acagtcccgt ggatccgaga taagggatta agaaaactag ataagatgac
     9781 cagcatactg ggaaggatat agaggagaaa gagacggggg gtgtcagcct gaaaatgttt
     9841 tgactcctga cgaattgttt ttaaatcaat ttttggatag ttcattctct tattatacca
     9901 tagttcttat acatagttcg tgacagttcc tacttttttt gataaaatca tacagtgtgt
     9961 ccttgggcac actgtatgaa ctgggactgt ctttcccagc ttcggaggta aaaaatgtca
    10021 gattcaccaa tcaaatatcg tttgattaag aaagaaaaac acacaggagc tcgtctagga
    10081 gaaatcatca ctccccacgg tacctttccg acacctatgt ttatgccagt tgggacacaa
    10141 gccactgtca aaactcagtc acctgaagaa ttgaaggaga tgggttcggg aattatccta
    10201 tcaaacacct atcatctctg gcttcgccct ggagatgaac tcattgcacg cgctggtggt
    10261 ctccacaagt tcatgaattg ggaccagcct atcttgacag atagtggtgg ttttcaggtt
    10321 tattctttag cagatagccg taatatcaca gaagaaggag taacctttaa aaatcatcta
    10381 aatggttcta agatgttcct atccccagaa aaagccatct ctattcagaa taatctgggt
    10441 tcagacatca tgatgtcctt tgatgaatgt cctcagtttt atcaacctta tgactacgtt
    10501 aagaaatcga tcgagcgtac cagccgttgg gctgagcgtg gtttgaaggc tcaccgtcgt
    10561 ccacatgacc aaggtttgtt tggaattgtg caaggtgcag gatttgaaga ccttcgccgc
    10621 caatcagctc atgatcttgt cagcatggat ttctcaggct actctatcgg tggtttggca
    10681 gtgggagaaa cccatgaaga gatgaatgcg gtcttggact ttacaactca actgctacct
    10741 gaaaataaac ctcgttatct gatgggtgtg ggagcgccag atagcttgat cgatggggtc
    10801 attcgtgggg tggatatgtt tgactgtgtc ttaccgactc gaattgctcg taacgggact
    10861 tgtatgacca gtcaaggacg tttggttgtg aaaaatgccc agtttgctga ggactttacg
    10921 ccactggatc ctgagtgtga ttgttacaca tgtaataact atacacgcgc ttaccttcgt
    10981 cacctgctca aggctgatga aacctttggt atccgcttga ctagctacca caatctttac
    11041 ttcttgctta acttgatgaa gcaagtgcga caagccatca tggatgacaa tctcttggaa
    11101 ttccgtgagt attttgtgga aaaatatggc tataataagt caggacgtaa tttctaaaat
    11161 ggaattgata taagctaaaa atcctaagtt ttctcttagg atttttcttc tttttttgat
    11221 agaataaagt gtacaatgaa aggaagaata aactcgtatg cgcattaaat ggttttcctt
    11281 gattaggatt ataggtttac ttttggtact cttgtatcac ttctttcaga cgatctttcc
    11341 tggaggattt ttcggggtag atgtcttttt cacattttca ggtttcctga ttacagctct
    11401 actcattgaa gaattttcta agaacaatga gattgatttg ataggatttt ttagaagacg
    11461 cttttatcgg attgtgccac ctgtggtttt gatggtcttg gtgaccatgc cttttacttt
    11521 cttggttcgc caagactatg ttgctggaat tggtggccag attgcgggcg tcttaggctt
    11581 tatgaccaac ttctatgaac tcctaacagg tgggagttat gaatctcagt tcattcctca
    11641 tttgtttgtt cataattgga gtttggcagt tgaggttcac tactatattc tttggggatt
    11701 ggcagtttgg ttcttatcca aacaagctaa atcaaatggt cagttgaagg ggatggtctt
    11761 tctcttatct gctgttgcct tcttgatcag tttcttctcc atgtttattg gtagttttct
    11821 agtgacctct tattcctctg tttatttctc cagtttaact catgtctatc cattcttttt
    11881 gggaagtatg ttagcaacta ttgtaggtgt tcgtcagacg acttccctcg tcaagcagtt
    11941 ggataaaatc tgggatttac gaaagacttt ggtagttttt ggaggaggct ttggtttcct
    12001 agttcttttg actttctttg tcaaattcac ttatcttttt gcctatctta tcggcttctt
    12061 gcttgccagt cttgcagctc ttgccatgat tctggcggcg cgtgtcttac atgaaaagac
    12121 acatcatata caggagccga agattatcag ctttttagcg gatactagct atgcggttta
    12181 tcttttccat tggcctttct atatcatttt ctcacagttg acatcaaatc ttcttgctgt
    12241 attactgact ctgatttgtt cttatggctt tgccagtctg tcattttatg tattggaacc
    12301 ttggattgca ggcaagaaca cacctatttt acaaactctt cgtcccctgc cttatattca
    12361 cgcaattctt gcagcaggta caggaatctt gacattcatt gtctgcatgg tgaccttgtt
    12421 ggcaccacaa gtgggagcgt ttgagacaga cttgactgtc aatggcttga agcaagctgc
    12481 aacaaatatt ggccagacca aggtgatggc agaacgggca gatgcaaaca gtttgggaat
    12541 tgctgatggc actatgttaa ttggtgactc agtggcttta agggcaaata cagcactaca
    12601 gacagctctt cctggagcac agattaacgc gcaggtcagc gtaacaacca agaccgcaaa
    12661 tgaaatcatg ctaaataata gccagaataa atttttacct aagacggtgg tcattgcgac
    12721 tggggtaaat aatcctgaga attacaagga tgactgggac agtatcgtga aaaatcttcc
    12781 taagggacac catatgattt tggtgactcc ttatgaggga gataagacaa aagagaccta
    12841 tgccatcgtt gagaaggctg ctgcctatat gagagaattg gcagagaaga caccttacat
    12901 tacgatagca gattggaatc aagttgcgaa agagcatcca gaaatttggg caggaacaga
    12961 ccaggttcat ttcgggagtg agagtagcac tatcgaagca ggagcaaaat tgtatgcaga
    13021 tacgattgcc acagctttgc agacagctca agataagccg gttaaatcaa aataacttgt
    13081 attaaaaaag agaagagttg gagaaatcca gctcttttaa aatatctcca aaaaataggt
    13141 ctataccatt tacaaataaa aaagaaaggt ttataatgta attgacataa taaattgtag
    13201 aatcaatctt ttaaggaggt taacattatg cctaactata ttaaagcgga tcagtttttc
    13261 tacccacacg gagttcgtcg aggtggttac ttggaacttg tggacggcaa gtttgggaaa
    13321 catgtagagc agattcctga aggggctgag gtgattgact atacaggtta tagcattgcc
    13381 ccaggtcttg tggatactca tattcatgga tatgcaggtg tagatgtgat ggacaacaac
    13441 attgaaggta cattgcatac tatgagtgaa ggacttctta gtaccggtgt taccagtttc
    13501 ttacccacaa ctttaacagc cacttatgag caattgcttg cagtcactga aaatcttgga
    13561 aaccattata aagaagcaac aggtgctaag attcgtggga tttattatga aggtccatat
    13621 ttcacagaaa cttttaaggg ggcacaaaat ccaacttata tgagagaccc gggtgttgag
    13681 gagtttcatt cttggcaaaa agcggcaaat ggcttgctta ataaaattgc ccttgcacca
    13741 gaacgtgatg gggtggaaga ctttgttcgt acagttacgg gcgaaggtgt gacggttgct
    13801 cttggacatt caaacgcgac ttttgatgaa gccaaaaaag cagtcgatgc tggagcgagt
    13861 gtttgggtgc atgcctacaa tggaatgcgt gggttgactc accgtgaatt gggtatggtt
    13921 ggagccatgt accaattgcc atatacctat gcagagttga tctgtgatgg tcaccacgta
    13981 gatccaaagg cttgcgaaat tcttatcaaa caaaaaggaa cagaaaacat cgctcttatc
    14041 acagactgta tgacagctgg gggattggaa gacggagatt atatgttggg agaattccca
    14101 gttgtcgttg caaatggaac tgcacgcctc aaatcgacag gtaacttggc aggttctatc
    14161 ctcaaactca aagatggttt gaagaatgtg gtcgaatggg gaattgcgaa tccgcatgaa
    14221 gcagtcatga tggccagctt caacccagct aaatccgttc acatcgatga cgtctgtggc
    14281 caaatccgtg aaggctacga cgctgacttc atcgtattag ataaagattt ggaattggta
    14341 gcaacctacc tagatggtgt gaaacgttat caagcataag agagaaggca gaagttagag
    14401 actagcttct gcttttttat acagggtact ttactggtaa ataaaaagtt aaaaaaatca
    14461 caaaaaaagc ttgaagaaac aaagaaaaag gcttacaatt gaactataaa tattacaaat
    14521 aaaaaaacgg aggagtgctt tatgaaagcc tatacttatg ttaaaccagg acttgcttct
    14581 tttgttgatg tagacaaacc agttattcgc aagccaacag atgctattgt gcgtattgta
    14641 aaaaccacta tttgtggaac agacctccat attatcaaag gggatgttcc tacttgccaa
    14701 agtggtacca ttcttggcca cgaagggatt gggattgttg aagaagttgg ggaaggagtt
    14761 tccaacttca aaaaaggtga caaggtcttg atttcttgcg tctgtgcctg tggtaaatgc
    14821 tactactgta aaaaaggaat ttatgcccac tgtgaagacg aagggggctg gattttcggt
    14881 cacttgattg atggtatgca ggctgaatat ctacgtgtcc ctcatgcaga taatactctt
    14941 taccatactc cagaagactt gtcagatgaa gctttggtta tgctgtcaga cattctgcct
    15001 actggatatg aaattggtgt cttaaaaggg aaagtagaac ctggttgtag cgtagccatt
    15061 attggttcag gtccagttgg attggctgct cttttaacag cccaattcta ttcaccagct
    15121 aaattgatta tggtagacct agacgataac cgcttggaaa ctgccctatc attcggtgcg
    15181 actcataagg ttaattcttc agaccctgaa aaagccatta aagaaattta tgatttgaca
    15241 gatggtcgtg gtgtggatgt cgctatcgaa gctgttggta ttcctgcaac atttgatttc
    15301 tgtcaaaaga ttatcggtgt agacggaacg gttgccaact gtggtgtgca tggtaaacca
    15361 gttgaattcg atttagataa actttggatt cgcaacatca atgtaacaac tggtttggta
    15421 tctacaaata cgactccaca attgttgaaa gcacttgaaa gtcataagat tgaaccagaa
    15481 aaattggtaa ctcactattt caaactcagt gaaattgaaa aagcctatga agtcttcagt
    15541 aaggcagcag accaccatgc cattaaggtc attatcgaaa acgatatctc agaagcctaa
    15601 gtagtaaaaa tatttttgta cataagtaaa tagaaattca gtcatccatc agatggctgg
    15661 attttttatc aaaaaattaa gaaatgagca tatttctttc cttgtctggc ggaattggtt
    15721 ataatatacg gtacaaagga atgaatgaat atgtatcgtg ttatagaaat gtacggagat
    15781 tttgaaccgt ggtggttctt agaaggttgg gaagaagata ttgtagcaag tagaaaattt
    15841 gaccagtatt atgatgctct caaatactac aaaacttgct ggtttagatt ggaacaagaa
    15901 tcccctcttt ataaaagtag aagcgacttg atgaccattt tttgggaccc ggaagaccaa
    15961 cgctggtgtg atgaatgtga tgagtattta caacaatacc attctttggc tcttttgcag
    16021 gatgagcagg ttatcccaga cgaaaaacta cgctcaggct atgaaaaaca aaccagtcag
    16081 gaaaggaatc gttcttgccg tatgaaatta aaatagagaa aagtaacttt tttggagttg
    16141 ctttttttat ttttctaacg ctttgcgaat agtataggtg aggaggtaag tatggttcaa
    16201 gaaattgcac aagaaatcat tcgttcggct cggaaaaaag gggcgcaaga catttatttt
    16261 gtccctaagt tagatgccta tgagcttcat atgagggtag gagacgagcg ctgtaaaatt
    16321 ggtagctatg attttgaaaa gtttgcagcc gttatcagtc actttaagtt tgtggcgggt
    16381 atgaatgtgg gagaaaaaag acgtagtcaa ctgggttcct gtgattatgc ctatgaccag
    16441 aagatagcgt ctctacgttt atctactgta ggcgattatc gggggcatga gagtttggtt
    16501 atccgtttgt tgcacgatga ggagcaggac ttgcattttt ggtttcagga tattgaagaa
    16561 ttaggcaagc agtacaggca acggggactc tatctttttg ctggtccggt tgggagtggt
    16621 aagacgacct tgatgcatga attgtccaag tcactcttta aaggacagca agttatgtcc
    16681 atcgaagatc ctgtcgaaat caagcaggac gacatgcttc agttgcagtt gaacgaagca
    16741 atcggcctaa cctatgaaaa tctaatcaaa ctttccttgc gtcatcgacc agatctcttg
    16801 attatcggag aaattcgtga cagcgagacg gcgcgtgcag tggtcagagc tagtttgaca
    16861 ggtgcgacag tcttttcaac cattcacgcc aagagtatcc gaggtgttta tgagcgtctg
    16921 ctggagttgg gtgtgagtga agaagaattt gcagttgttc tgcaaggagt ctgctaccag
    16981 agattaatcg ggggaggagg aatcgttgac tttgcaagca gagattatca agaacaccaa
    17041 gcagccaagt ggaatgagca aattgaccag cttcttaaag atggacatat cacaagtctt
    17101 caggctgaga cggaaaaaat tagctacagc taagcaaaaa aatatcatca ccctatttaa
    17161 caatctcttt tctagcggtt ttcatctggt ggagaccatc tcctttttag ataggagtgc
    17221 tttgttggac aagcagtgtg tgacccagat gcgtgtgggc ttgtctcagg ggaaatcatt
    17281 ctcagaaatg atggaaagtt tgggatgttc aagtgctatt gtcactcagt tatccctagc
    17341 tgaagtccat ggcaatctcc acctgagttt gggaaagata gaagagtatc tagacaatct
    17401 ggccaaggtc aagaaaaaat taattgaagt agcgacctat cctttgattt tgctgttttt
    17461 tcttctctta attatgctgg ggctacggaa ttacctgctc ccacaactgg atagtagcaa
    17521 tattgccacc caaattatcg gtaatctgcc acaaatcttt ctaggaatga tagtttttgt
    17581 ttcagtaggt gtccttttag cactcacttt ttataaaaga agttctaaga tgcgcgtctt
    17641 ttctatctta gcgcgccttc cttttattgg aatctttgtg cagacctatt tgacagccta
    17701 ttatgcacgt gaatggggga atatgatttc acagggaatg gagttgacgc agatttttca
    17761 aatgatgcag gaacaaggtt cccagctctt taaagaaatc ggtcaagatc tggctcaaac
    17821 cctgaaaaat ggccgtgaat tttctcagac gataggaacc tatcctttct ttaggaagga
    17881 attgagtctc atcatagagt atggggaagt taagtccaag ctgggtagtg agttggaaat
    17941 ctatgctgaa aaaacttggg aagccttttt tacccgagtc aaccgcacca tgaatttggt
    18001 gcagccactg gtttttatct ttgtggcact gattatcgtt ttactttatg cggcaatgct
    18061 caggcccatg tatcaaaata tggaggtaaa tttttaaaat gaaaaaaatg atgacattct
    18121 tgaaaaaagc taaggttaaa gcttttacat tggtggaaat gttggtggtc ttgctgatta
    18181 tcagcgtgct tttcttgctc tttgtaccta atctgaccaa gcaaaaagaa gcagtcaatg
    18241 acaaaggaaa agcagctgtt gttaaggtgg tggaaagcca ggcagaactt tatagcttgg
    18301 aaaagaatga agatgctagc ctaagcaagt taaaagacga tgggcgaatc acggaagaac
    18361 aggttaaagc ttataaagaa tacaatgata aaaatggagg agcaaatcgt aaagtcaatg
    18421 attaaggcct ttaccatgct ggaaagtctc ttggttttgg gtcttgtgag tatccttgcc
    18481 ttgggcttgt ccggctctgt tcagtccact tttgcggcag tagaggaaca gattttcttt
    18541 atggaatttg aagaactcta tcgggaaacc caaaaacgca gtgtagccag tcagcaaaag
    18601 actagtctga acttagatgg gcagacgatt agcaatggca gtcaaaagtt gccagtccct
    18661 aaaggaattc aggtcccatc aggccaaagt attacatttg accgtgctgg gggcaattcg
    18721 tccctggcta aggttgaatt tcagaccagt aaaggagcga ttcgctatca attatatcta
    18781 ggaaatggaa aaattaaacg cattaaggaa acaaaaaatt agggcagtga ttttactgga
    18841 agcagtagtc gctctagcta tctttgccag cattgcgacc ctccttttgg gacaaattca
    18901 aaaaaatagg caagaggaag caaaaatctt gcaaaaggaa gaagtcttga gggtagctaa
    18961 gatggccttg cagacaggtc aaaatcaggt aaacataaac ggagttgaga ttcaggtgtt
    19021 ttctagcgaa aagggattgg aggtctacca tggttcagaa cagttgttgg caatcaaaga
    19081 gccataaggt caaggctttt accttgttag aatccctgct tgccctgctt gtcatcagtg
    19141 ggggcttact cctttttcaa gctatgagtc agctcctcat ttcagaagtt cgctaccagc
    19201 aacaaagcga gcaaaaggag tggattttgt ttgtggacca acttgaggca gaattagacc
    19261 gttcgcagtt cgaaaaagta gaaggcaatc gcctatacat gaagcaagat ggcaaggaca
    19321 tcgccatcgg taagtcaaag tcagacgatt ttcgtaaaac cgatgctagt ggacgggggt
    19381 atcagcctat ggtttatggc ctcaaatcag ctcagattac agaggacaat caactggttc
    19441 attttcgttt ccagtttcaa aaaggcttag aaagggagtt catctatcgt gtggaaaaag
    19501 aagaaagtta aggcaggtgt tctcctctat gcagtcacca tggcagctat ctttagtctt
    19561 ttgttgcaat tttacttgaa ccgacaagtc gcccactatc aagactatgc tttgaataaa
    19621 gaaaaattgg ttgcttttgc catggctaaa cgaaccaagg ataaagccga gcaagaaagt
    19681 ggggaacagg tctttaatct aggtcaggta agctatcaaa acaagaaaac aagcttggtg
    19741 acgactgttc gtacggataa gagtcaatat gagtttctgt ttccttcagt caaaatcaaa
    19801 gaagagaaaa gagataaaaa ggaagaggta gcgaccgatt caagcgaaaa agtggagaag
    19861 aaaaaatcag aagagaagcc tgaaaagaaa gagaattcct agtcaattca actataatgc
    19921 gttgaatcca gaatagtcca ctgtagtttc tagaaaattg ctggaaatgg atgttaagct
    19981 ccaattcatt tgtttatatc ttatttcagt ttactatact ttgtgctaaa ttaaagatat
    20041 gaaacatgat tttaaccaca aagcagaaac tttcgatttc cctaaaaata tcttcctcgc
    20101 aaacttggta tgtcaagcag ccgagaaaca gattgatctt ctatcagaca aagaaatttt
    20161 agatttcggt ggtggcacgg gtctattagc cttgccccta acccctagcc aagcaggcta
    20221 agtcagtcac tcttgtagac atttctgaga aaatgttgga gcaagctcgt ttgaaagtgg
    20281 agcagcaagc aatcaagaat atccagtttt tggagcaaga tttaccgaaa aatcccttgg
    20341 agaaagagtt tgattgcctt gctgttagtc gggttcttca tcatatgcct gatttggatg
    20401 cggctctctc actgtttcat caacatttga aggaagatgg gaaactcatc attgctgatt
    20461 ttaccaagac agaagctaat catcatggat ttgatttagc tgaactggaa aacaagctaa
    20521 ttgagcatgg tttttcatct gtgcatagtc agattctcta tagcgctgaa gacctgtttc
    20581 aaggaaatca ctcagaattc tttttaatag tagcccaaaa atcactcgcc tagtcaggga
    20641 gtgatttttc tataagaatg gaaaaaagaa gggaaatttg ataagatagg aatatggatt
    20701 ttgaaaaaat tgaacaagct tatacctatt tactagagaa tgtccaagtc atccaaagtg
    20761 atttggcgac caacttttat gacgccttgg tggagcaaaa cagcatctat ctggatggtg
    20821 agactgagct agaacaggtc aaagacaaca atcagaccct taagcgttta gcactacgca
    20881 aagaagaatg gctcaagacc taccagtttc tcttgatgaa ggctgggcaa acagaaccct
    20941 tgcaggccaa tcaccagttt acaccggatg ctattgcttt acttttggtg tttattgtgg
    21001 aagagctgtt taaagaggag gaaattacta tcctcgaaat gggttctggg atgggaattt
    21061 tgggcgctac tttcttgacc tcgcttacta aaaaggtgga ttatttggga atggaagtgg
    21121 atgatttgct gattgatttg gcagctagca tggcagatgt aattggtttg caggctggct
    21181 ttgtccaagg agatgccgtt cgtccacaaa tgctcaaaga aagtgatgtg gtcatcagcg
    21241 acttgcctgt tggctattat cctgatgatg ccgttgcgtc gcgccatcaa gttgcttcta
    21301 gtcaagaaca tacttacgcc catcacttgc tcatggaaca aggacttaag tacctcaagt
    21361 cagacggata cgctattttt ctagctccga gtgatttgtt gaccagtcct caaagtaatt
    21421 tgttgaaagt ctggttgaaa gaggaggcaa gtctggttgc tatgattagt ttacctgaaa
    21481 atctctttgc taatgctaaa caatctaaga ctatttttat cctacagaag aaaagtgaaa
    21541 tagcagtaga gccttttgtt tatccacttg ctagcttgca agatgcaagt gttttaatga
    21601 aatttaaaga aaattttcaa aaatggactc aaggtactga aatataaaat agattttgtt
    21661 ataatagttg aaaacgctta aaaaggggta tcatgttatg acaaaaacaa ttgcaatcaa
    21721 tgcaggaagt tcaagcttaa aatggcaatt atacttaatg ccagaagaaa aagtattggc
    21781 gaaaggcttg attgaacgta tcggtttgaa agattcaatt tcaactgtaa aatttgacgg
    21841 ccgttctgaa caacaaattt tggatatcga aaatcataca caagccgtta aaattttatt
    21901 ggatgacttg attcgtttcg atattatcaa ggcttatgac gagattacag gtgttggcca
    21961 ccgtgttgta gcaggtggag aatatttcaa agaatcaaca gttgttgagg gagatgtttt
    22021 agaaaaagtt gaagagttga gtttgttggc tcctctacac aacccggcca atgcagcagg
    22081 tgttcgtgcc ttcaaggaat tgttgccaga cattaccagt gtagttgttt ttgatacttc
    22141 cttccacaca agtatgccag agaaagctta tcgctaccct ctaccaacaa aatattacac
    22201 agaaaacaag gttcgtaaat acggtgctca tggtacaagt caccagtttg tagcaggaga
    22261 agctgcaaaa ctcttgggac gtccattaga agacttgaag ttaattacct gtcatattgg
    22321 taacggaggc tcaattacag ctgtgaaagc cggcaaatct gtagacactt ctatggggtt
    22381 cactcctctt ggtggtatta tgatgggaac gcgtacaggg gatattgatc cagctatcat
    22441 tccttattta atgcaatata cagaggattt taacacacca gaagatatca gtcgtgttct
    22501 taaccgtgaa tcaggtcttt tgggagtttc tgctaattct agcgatatgc gcgatataga
    22561 agcagctgta gcagaaggga atcacgaggc tagcttggct tatgaaatgt atgttgaccg
    22621 tatccaaaaa catatcggtc agtaccttgc agtgctaaat ggagcagatg ccattgtttt
    22681 cacagcaggt gtcggtgaaa atgcagagag tttccgtcgt gatgtaatct cagggatttc
    22741 gtggtttggt tgtgatgttg atgatgaaaa gaatgtcttt ggcgttacag gagacatctc
    22801 aacagaggca gctaaaatcc gtgtcttggt tattccaaca gatgaagaat tagtcattgc
    22861 ccgtgacgtt gaacgcttga aaaaataagt gaaactaaaa aaatattcaa tacaaggagt
    22921 tgggaaagtt atttttccag cttctttttc tgatgaaatt gtccaaaacc ttgctatgat
    22981 tggctttttt gaaaaatatg gtataatagt agtaatttaa tagatggagt tgagttttga
    23041 agaaaaactt tcgtgtaaaa agagagaaag attttaaggc gattttcaag gaggggacaa
    23101 gttttgctaa tcgcaaattt gtggtctacc aattagaaaa ccagaaaaac cattttcgag
    23161 taggtctatc agttagcaaa aaactgggga atgccgtcac tagaaatcaa attaagcgac
    23221 ggattcggca tattatccag aatgcaaaag ggagtctggt agaagatgtc gactttgttg
    23281 tcattgctcg aaaaggagtc gaaaccttgg gatacgcaga gatggagaaa aatctactcc
    23341 atgtattaaa attatcaaag atttaccggg aaggaaatgg gagtgaaaaa gaaactaaag
    23401 ttgactagtt tgctaggact gtctctgtta atcatgacag cctgtgcgac taatggggta
    23461 actagcgata ttacagccga atcggctgat ttttggagta aattggttta cttctttgcg
    23521 gaaatcattc gctttttatc gtttgatatt agtatcggag tggggattat tctctttacg
    23581 gtcttgattc gtacagtcct cttgccagtc tttcaggtgc aaatggtggc ttctaggaaa
    23641 atgcaggaag ctcagccacg cattaaggcg cttcgagaac aatatccagg tcgagatatg
    23701 gaaagcagaa ccaaactaga gcaggaaatg cgtaaagtat ttaaagaaat gggtgtcaga
    23761 cagtcagact ctctttggcc gattttgatt cagatgccgg ttattttggc cctgttccaa
    23821 gccctatcaa gagttgactt tttaaagaca ggtcatttct tatggattaa ccttggtagt
    23881 gtggatacaa cccttgttct tccgatttta gcagcagtat tcaccttttt aagtacttgg
    23941 ttgtccaaca aagctttgtc tgagcgaaat ggcgctacga ctgcgatgat gtatgggatt
    24001 ccagtcttga tttttatctt tgcagtttat gcgccaggtg gagtcgccct atactggaca
    24061 gtgtctaatg cttatcaagt cttgcaaacc tatttcttga ataatccatt caagattatc
    24121 gcagagcgcg aggccgtagt acaggcacaa aaagatttgg aaaatagaaa aagaaaagcc
    24181 aagaaaaagg ctcagaaaac gaaataaata aggaggaatc tggtaatggt agtatttaca
    24241 ggttcaactg ttgaagaagc aatccagaaa ggattgaaag aattagatat tccaagaatg
    24301 aaggctcata tcaaagtcat ttctagggag aaaaaaggct ttcttggtct atttggtaaa
    24361 aaaccagccc aagtggatat tgaagcgatt agtgaaacga ctgttgtcaa agcaaatcaa
    24421 caggtagtaa aaggcgttcc gaaaaaaatc aatgatttga acgagcctgt gaagacggtt
    24481 agtgaagaaa ccgttgacct tggtcatgtg gttgatgcta ttaaaaaaat agaggaagaa
    24541 ggtcaaggta tttctgatga agtcaaggct gaaatcttaa aacatgaaag acatgccagc
    24601 actatcttag aagaaactgg tcacattgag attttaaatg aacttcaaat cgaggaagcg
    24661 atgagggaag aagcaggcgc tgatgacctt gaaactgagc aagatcaaac tgaaaatcaa
    24721 gacttgaaag agatgggctt gaaggtcgag caaagttatg atattgccca ggtggctacg
    24781 gatgtgactg cttatgttca aacgattatt gatgacatgg atgttgaggc tacactttca
    24841 aatgattata accgtcgtag catcaatttg caaattgata ctaacgaacc aggtcgtatt
    24901 atcggctacc atggtaaagt cttgaaggcc ttgcaactgt tggctcaaaa ttatctttac
    24961 aactgctatt caagaacctt ctatatcact attaatgtca atgattatgt tgaacaccgt
    25021 gcagaagtct tgcagaccta tgcgcaaaaa ttggcgattc gtgttttaga agaagggcgc
    25081 agtcatcaaa cagatccaat gtcgaatagt gaacgcaaga ttatccaccg tattatttca
    25141 cgtatggatg gcgtgaccag ttactctgaa ggtgatgagc caaatcgcta tgtcgttgta
    25201 gatacagaat aagtaaaatc agggttgacc tgattttttg ctagctagag gaggttaaac
    25261 tgatgttgaa taagataaga gactatctag acttttctgg tttgcagtac cgtagtcctg
    25321 ataaagcggg agcagagcga gagaagatgc tggcgttccg ccacaaagga caagaggccc
    25381 gaaaggcttt tacagaactg gccaaagcct ttcaagcaag ccatccagaa tggcaactcc
    25441 aacagactag tcagtggatg aatcaggccc agcgtttgag accacatttt tgggtttatc
    25501 tacagagaga cggacaagtg acagaaccta tgatggcctt acgtttgtat gggacatcta
    25561 ctgactttgg aatttctttg gaagtcagtt tcatcgaacg taagaaggat gagcaaacac
    25621 tgggcaagca gaccaaagtt ttagacattc caaccgttaa agggatttat tatctaacct
    25681 actctaatgg tcaaagtcaa cggtgggagg cgaatgaaga aaagcgtcgt actttacgcg
    25741 agaaggtgag aagtcaagaa gttcgaaaag ttttagtgaa ggtagatgtt cctatgacag
    25801 aaaattcgtc tgaagaagag atcgtagaag gcttattgaa gtcttattct aaaattcttc
    25861 cctattatct agctacgaga aaataagata atttgtaaaa catcataaat catacagtcc
    25921 aagagtgaac agtccgctgt gtaattcttg gtctttttgt ttgcgctttc gcattatata
    25981 ataaacttac aaaaacaatt caaaaggaga acaattatgg aagtcgtttc aagtgttcta
    26041 aattggtttt ctagcaatat tttgcagaat cccgcatttt tcgtaggttt attggtgttg
    26101 ataggatatg cacttttgaa aaaacctgcc catgacgttt tttcagggtt tgttaaagca
    26161 acagtagggt atatgttgct taacgtgggt gctggtggtt tggttacaac ctttcgtcca
    26221 atcttagcag ctcttaacta caaattccaa attggtgcag cggttatcga cccttacttt
    26281 ggacttgctg cagcaaacaa caaaattgca gcagagtttc cagattttgt tggaactgca
    26341 actacagctc tattgattgg ttttggaata aatatcttgc tcgtagctct tcgaaagatt
    26401 acgaaggtaa gaaccctctt tattactggt cacatcatgg tacaacaagc tgcaacagta
    26461 tctcttatgg ttctattctt agtaccacaa ttgcgcaatg cttacggtac agcagcgatt
    26521 ggtatcatct gtggacttta ctgggcagtt agttcaaata tgactgttga ggcaactcaa
    26581 cgcttgactg gtggtggcgg atttgcgatt ggtcaccaac agcaatttgc aatctggttt
    26641 gtagataaag tagcaggacg ctttggtaag aaagaagaaa gtttagacaa tcttaaatta
    26701 cctaagttcc tctcaatctt ccacgataca gttgttgcat ctgctacctt gatgctcgta
    26761 ttcttcggag ccattctttt aatcttgggt ccagacatta tgtctaataa agaagtcatc
    26821 acttcaggaa ctctattcaa tcctgctaaa caagatttct ttatgtacat tatccaaaca
    26881 gcttttacct tctcagttta cttgttcgtt ttgatgcaag gtgtccgaat gttcgtatct
    26941 gagttgacaa acgccttcca aggtatttca aacaaattgt taccaggttc attcccagcg
    27001 gttgacgttg cagcttctta tggatttggt tctccaaatg ctgtcctgtc aggatttata
    27061 tttggtttga ttggtcaatt gattacaatt gttttactca tcgtctttaa aaatccgatt
    27121 cttattatta caggatttgt accagtgttc tttgacaatg cagccattgc ggtctacgct
    27181 gataaacgcg gcggatggaa agcggctgtt atcctttcct ttatatcagg tgtccttcaa
    27241 gttgctctag gagctctttg tgtggccctt ctcgatttgg catcttatgg tggctaccat
    27301 ggaaatatcg actttgaatt cccatggctt ggatttggat atatcttcaa ataccttggt
    27361 attgttggtt atgtacttgt gtgtctcttc ttgcttgtta ttcctcaact tcaatttgcc
    27421 aaagcaaaag ataaagagaa atattacaac ggtgaagttc aagaagaagc ttagtatcta
    27481 gaaaaggaga aataaaatgg ttaaagtatt agcagcgtgc ggaaatggaa tgggttcatc
    27541 aatggttatc aagatgaagg ttgaaaatgc tctccgtaag cttaatcaaa cagattttac
    27601 agtcaattca tgcagtgtcg gtgaagctaa aggtttagca gtaggatatg acatcgtaat
    27661 cgcttctctt catttgattc aagaattgga agggcgaact aatgggaagt taattgggct
    27721 tgataacttg atggatgata aagaaatcac cgaaaaactc agtcaagcac tacagtaaaa
    27781 ggttggaggg ggctggacag aaactgagag ttatcgtttc tgtccttctc cctctttaaa
    27841 taaaggaggc agatatgaat ttaaaacaag ctttaattga caacgactcg atccgactag
    27901 gtttagaggc taacgattgg aaagaagcag tcaaggtagc agtagatccc ttgattgaaa
    27961 gtggggcaat tttgccagag tattacgatg ctatcattga atcgactgaa gagtatgggc
    28021 cttactatat cttgatgcca ggtatggcta tgccccacgc tagacctgaa gctggtgtgc
    28081 aaagtgatgc cttttcatta attaccttac aaaatcctgt tgtattttca gatgggaaag
    28141 aggtatctgt tttgttggca ctagcagcaa caagttcaaa aattcacaca agtgtagcca
    28201 ttccacaaat tattgccctg tttgaattag aagattctat tgcacgttta caggcttgcc
    28261 agactaaaga agatgtcttg gctatgattg aagaatctaa ggatagccct tatctcgaag
    28321 gattggattt ggaaagttag aaagaggaat aaagaaatga caaaaagaat acctaattta
    28381 caagttgcat tagaccattc agacttgcaa ggagcgatta aagcagctgt ttctgttggt
    28441 caggaagtag atattatcga agctggaact gtttgcttgc ttcaagttgg aagtgaactg
    28501 gctgaagtct tgcgtagcct tttcccagat aagattattg tggcagacac aaaatgtgct
    28561 gatgctggtg gaacagttgc taaaaataat gcggttcgtg gagcagactg gatgacttgt
    28621 atctgttgtg caaccatccc tactatggaa gcagctctaa aggctatcaa gactgaacga
    28681 ggagaacgag gcgaaatcca gatcgagctt tatggcgatt ggacttttga acaagctcag
    28741 ctttggctag atgcaggtat ctcacaagct atttatcacc aatctcgtga tgctcttctt
    28801 gctggtgaaa cttggggtga aaaagacctt aataaggtta aaaaactcat tgacatgggc
    28861 ttccgtgtat ctgtaacagg tggtctagat gtagatactc tcaaactctt tgaaggtgtt
    28921 gatgtcttta cctttatcgc aggtcgtgga attacagagg ctgtggatcc agcaggagca
    28981 gcgcgtgcct tcaaggatga aatcaaacga atttgggggt aaatcatggt acgtccaatt
    29041 ggaatttatg aaaaggcaac cccaacacac tttacttggc tagaacgttt aaattttgcc
    29101 aaggagttag gctttgattt tatcgagatg tctattgacg aacgtgacga gcgtttagca
    29161 agacttgact ggagtaagga agaacgcttg gaagttgtca aagaaatcta tgaaactggt
    29221 gttcgtattc cttctatctg tttttcaggc catcgtcgct acccattggg atcaaaagat
    29281 tcagttctag aggaaaaatc tctagaactc atgaaaaaat gtatcgaatt agctcaagac
    29341 ttgggagttc gtacaattca attagctggt tacgatgttt actatgagga aaagtcaccc
    29401 cagacacgcc aacgttttat caaaaatttg agaaaagcct gtgactgggc tgaagaagct
    29461 caggtggtac ttgctattga aattatggat gatcctttca tcaatagcat cgaaaaatat
    29521 ttggctatag aaaaagagat tgactctccc ttcctctttg tatatccaga tattggtaat
    29581 gtgtctgcat ggcataatga tatctatagt gagttttatc ttggtcatca tgccatcgca
    29641 gctctccatc tcaaggatac ttatgcagtg acagaaagtt caaagggcca gttccgagat
    29701 gtacctttcg ggcaaggttg tgtcaaatgg gaagaagctt tcgatatttt aaaggaaacc
    29761 aattataatg gacctttcct aatcgaaatg tggtctgaaa attgtgaaac agtagaagaa
    29821 acacgcgcag ccattcaaga ggcgcaagct tttctctatc cactcattaa gaaagcaggt
    29881 ttgatgtaag atgaatcaag taatcaatgc tatgcgtaaa cgagtctgtg atgccaatca
    29941 atcattgcca aaacatggac ttgtcaaatt tacctggggg aatgtatctg aagtcaatcg
    30001 cgaactcggt gtcattgtta tcaaaccatc aggcgtggat tatgacgaat tgacacctga
    30061 aaacatggta gtgactgatc tagatggtaa gatcctagaa ggggatttaa gaccatcttc
    30121 cgacctccca actcatgtgc aattatataa ggcttggtca gaaattggta gtgtggttca
    30181 cacccattcg acagaagctg ttggttgggc tcaggcaggt cgtgatattc ctttctacgg
    30241 aacaacccat gcagattatt tctacggttc aatcccttgc gcccgtagtt tgaccaagga
    30301 cgaagtagaa gtgacctatg aaaaagatac tggcctggtt atcgtagaag agtttgaaca
    30361 tcgcggactt aacccagttg aagtaccagg aattgttgta cgcaatcacg gtccattcac
    30421 ctggggcaaa aatccagaga atgctgttta tcactctgtc gtactagagg aagtatcaaa
    30481 gatgaatcgc tttacagaac aaatcaatcc aagagttgga cctgctcccc agtacatact
    30541 agaaaaacac taccaacgta aacatggacc aaatgcttat tatggtcaaa agtaagaacg
    30601 atgaaggagg agaaaaagat aaatttagct cctcttttta catttgattt ttattgagag
    30661 taaagttgga gttgaagtaa ttttgaaaga ttttttagaa atagcgcttg atatatatgg
    30721 taaaataaaa agaattgctg tgatatcaat agatttgggg gattttttaa tatggtactg
    30781 gataaggcaa gttgtgattt gcttcaatat ttgatggatc aagaaacgtc caaaacgatt
    30841 atggcgattt cgaaagattt gaaagagtca agaaggaaaa tttattatca cattgacaaa
    30901 atcaatgctg ctctggttga cgaggcgctt cacatcatta gtattccacg aattggtatt
    30961 cacttaacgg aagagcagag agatgcttgt tgtaaactat tatcggaagt agattcgtac
    31021 gattatatca tgagtgcgca tgaacgtatg atgataatgt tactatggat aggtatttct
    31081 aaagaacgta ttacgattga aaaattgata gagttaacag aggtatctag gaatactgtt
    31141 ctcaatgatt tgaatagtat tcgttatcaa ctaactttgg aacaatatca ggtgatcttg
    31201 caagtgagca agtcacaggg ataccacctt catgcccacc ctcttaataa aattcagtat
    31261 cttcaatcgc ttctatatca tatttttatg gaagaaaatg ccacttttgt atctatttta
    31321 gaagataaga tgaaagagag gttagatgat gagtgtttgc tttctgttga aatgaaccaa
    31381 ttttttaagg aacaggttcc tttagttgaa caagatttag ggaagaaaat aaaccatcat
    31441 gaaataactt t
//
LOCUS       DBERPV010000023        31097 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.23, whole genome shotgun sequence.
ACCESSION   DBERPV010000023 DBERPV010000000
VERSION     DBERPV010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 31097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31097
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.23"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(22..663)
                     /locus_tag="ACL8C7_001336"
                     /pseudo
     CDS             complement(22..663)
                     /locus_tag="ACL8C7_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            complement(772..1290)
                     /locus_tag="ACL8C7_001337"
     CDS             complement(772..1290)
                     /locus_tag="ACL8C7_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HGS1395525.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(1327..1455)
                     /locus_tag="ACL8C7_001338"
                     /pseudo
     CDS             complement(1327..1455)
                     /locus_tag="ACL8C7_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CD1845 family protein"
     gene            complement(1517..2386)
                     /gene="rsmI"
                     /locus_tag="ACL8C7_001339"
     CDS             complement(1517..2386)
                     /gene="rsmI"
                     /locus_tag="ACL8C7_001339"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HGS1395526.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGTSAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGL
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQDVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(2389..2706)
                     /gene="yabA"
                     /locus_tag="ACL8C7_001340"
     CDS             complement(2389..2706)
                     /gene="yabA"
                     /locus_tag="ACL8C7_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HGS1395527.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(2746..3636)
                     /locus_tag="ACL8C7_001341"
     CDS             complement(2746..3636)
                     /locus_tag="ACL8C7_001341"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HGS1395528.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(3633..4271)
                     /gene="tmk"
                     /locus_tag="ACL8C7_001342"
     CDS             complement(3633..4271)
                     /gene="tmk"
                     /locus_tag="ACL8C7_001342"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HGS1395529.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLEKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            complement(4491..5288)
                     /gene="proC"
                     /locus_tag="ACL8C7_001343"
     CDS             complement(4491..5288)
                     /gene="proC"
                     /locus_tag="ACL8C7_001343"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HGS1395530.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLSKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGIVMEAVHQAYKRTQELGK"
     gene            complement(5292..6554)
                     /locus_tag="ACL8C7_001344"
     CDS             complement(5292..6554)
                     /locus_tag="ACL8C7_001344"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HGS1395531.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            complement(6564..7673)
                     /gene="proB"
                     /locus_tag="ACL8C7_001345"
     CDS             complement(6564..7673)
                     /gene="proB"
                     /locus_tag="ACL8C7_001345"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HGS1395532.1"
                     /translation="MKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAMLHEAGHEL
                     ILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQIVSAQILL
                     TQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSAQVAAMVQ
                     ADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMSGGAGSSNGTGGMLTKIK
                     AATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLAFYAQSQG
                     SIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKGRVQFGAS
                     ALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(7774..9657)
                     /gene="cbpE"
                     /locus_tag="ACL8C7_001346"
                     /gene_synonym="pce"
     CDS             complement(7774..9657)
                     /gene="cbpE"
                     /locus_tag="ACL8C7_001346"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HGS1395533.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDNRITNSERLWDNLYGYDKVLQT
                     ASEKGVSVIQNITQGDAHFQFGDMDIELYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWIKERGIERINAASKDYDATVFDIRQDGLVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFY
                     LTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTDGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            complement(9660..10547)
                     /locus_tag="ACL8C7_001347"
     CDS             complement(9660..10547)
                     /locus_tag="ACL8C7_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGS1395534.1"
                     /translation="MEIKIETGGLRLDKALSALSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHSVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(10537..10998)
                     /gene="lspA"
                     /locus_tag="ACL8C7_001348"
     CDS             complement(10537..10998)
                     /gene="lspA"
                     /locus_tag="ACL8C7_001348"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HGS1395535.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(10995..11903)
                     /locus_tag="ACL8C7_001349"
     CDS             complement(10995..11903)
                     /locus_tag="ACL8C7_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGS1395536.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKSQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLREGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            11932..12084
                     /locus_tag="ACL8C7_001350"
     CDS             11932..12084
                     /locus_tag="ACL8C7_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGS1395537.1"
                     /translation="MIPYFRSFPKRKKEHPILLHYLPFSSQPYFQNQFKKISGYTPLQ
                     YRKEKR"
     gene            complement(12136..12807)
                     /locus_tag="ACL8C7_001351"
     CDS             complement(12136..12807)
                     /locus_tag="ACL8C7_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGS1395538.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISPPS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(12861..13082)
                     /locus_tag="ACL8C7_001352"
     CDS             complement(12861..13082)
                     /locus_tag="ACL8C7_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HGS1395539.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKEPNGYYPWQMEPVLTMP
                     VHGFCPRGTDDLGYIGGGNHLCKGSAARF"
     gene            13355..14164
                     /locus_tag="ACL8C7_001353"
     CDS             13355..14164
                     /locus_tag="ACL8C7_001353"
                     /EC_number="3.-.-.-"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGS1395540.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHIAAIHQAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(14345..15220)
                     /gene="aguB"
                     /locus_tag="ACL8C7_001354"
     CDS             complement(14345..15220)
                     /gene="aguB"
                     /locus_tag="ACL8C7_001354"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0050126 - N-carbamoylputrescine amidase
                     activity [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HGS1395541.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(15230..16315)
                     /gene="aguA"
                     /locus_tag="ACL8C7_001355"
     CDS             complement(15230..16315)
                     /gene="aguA"
                     /locus_tag="ACL8C7_001355"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047632 - agmatine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HGS1395542.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKDAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(16312..17439)
                     /gene="nspC"
                     /locus_tag="ACL8C7_001356"
     CDS             complement(16312..17439)
                     /gene="nspC"
                     /locus_tag="ACL8C7_001356"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0045312 - nor-spermidine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HGS1395543.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEVGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(17439..18698)
                     /locus_tag="ACL8C7_001357"
     CDS             complement(17439..18698)
                     /locus_tag="ACL8C7_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HGS1395544.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(18695..19555)
                     /gene="speE"
                     /locus_tag="ACL8C7_001358"
     CDS             complement(18695..19555)
                     /gene="speE"
                     /locus_tag="ACL8C7_001358"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HGS1395545.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQSFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
     gene            19811..20415
                     /locus_tag="ACL8C7_001359"
                     /pseudo
     CDS             19811..20415
                     /locus_tag="ACL8C7_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846390.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            20395..20520
                     /locus_tag="ACL8C7_001360"
                     /pseudo
     CDS             20395..20520
                     /locus_tag="ACL8C7_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812181.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(20492..21967)
                     /locus_tag="ACL8C7_001361"
     CDS             complement(20492..21967)
                     /locus_tag="ACL8C7_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HGS1395546.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            22674..23723
                     /locus_tag="ACL8C7_001362"
                     /pseudo
     CDS             22674..23723
                     /locus_tag="ACL8C7_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153810.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            23665..24339
                     /locus_tag="ACL8C7_001363"
     CDS             23665..24339
                     /locus_tag="ACL8C7_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HGS1395547.1"
                     /translation="MDSNFAGRLNILRAGVLGANDGIISIAGVVIGVASATTNIWIIF
                     LSGFAAILAGAFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQN
                     GECKTSAQLLTNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPML
                     SVTIFPSEYRIPATVLIVGVALLLTGYTSARLGKDPTRTAMIRNLAIGLLTMGVTFLL
                     EQLFSI"
     gene            complement(24381..26369)
                     /locus_tag="ACL8C7_001364"
     CDS             complement(24381..26369)
                     /locus_tag="ACL8C7_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1395548.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTITYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVLFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(26371..27129)
                     /locus_tag="ACL8C7_001365"
     CDS             complement(26371..27129)
                     /locus_tag="ACL8C7_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1395549.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSATLLDVFNEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQLFQEISDTLTVMASEVN"
     gene            27557..27748
                     /locus_tag="ACL8C7_001366"
     CDS             27557..27748
                     /locus_tag="ACL8C7_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395550.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFISTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            complement(28102..28374)
                     /locus_tag="ACL8C7_001367"
     CDS             complement(28102..28374)
                     /locus_tag="ACL8C7_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HGS1395551.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(28432..28881)
                     /locus_tag="ACL8C7_001368"
     CDS             complement(28432..28881)
                     /locus_tag="ACL8C7_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HGS1395552.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKVYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQTYQRKRRIDTQRYRCGLCRGKLLLVNQPED"
     gene            complement(28868..30997)
                     /locus_tag="ACL8C7_001369"
     CDS             complement(28868..30997)
                     /locus_tag="ACL8C7_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HGS1395553.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
BASE COUNT         9162 a         6963 c         5687 g         9285 t
ORIGIN      
        1 attatcaatc ataaactaga attctagttt tgcaggaagt ctaatgtaat tctcaagctg
       61 tgagttcatt atgatttgta aatccgatat atcttcagca gctaaaaaca cattttgaaa
      121 tgttccaagt ccgttttcac caaaactata ttctctctta ctatacttac tcttattatt
      181 ctctatatag ttagagtcaa ggttcttaac ctcttgaagt tcattttctt tacttctgag
      241 gttaaaatct tttacttctg aagttaagtt ttttgacttc tgtaagtcat tttcttttac
      301 ctgaaatata ctcataaagt ctttaacata aatgatgttc ggcttaccaa gtccaagcct
      361 tactctttcg atcagtccta ttcctttttt tacatcaagc tcatctaatg tttttatggc
      421 agttggcttt gagatatttc ttcttttcat aatttcttcg acagtaaaat agataaatac
      481 tctgccttcc ttgtctatcc agttattctt aaatgacatt cctgtctatt taagaagtat
      541 ggaataaagg ataattgctt ctgctgataa gccccgaaat tcttctctat caactaatat
      601 ctccggtact tttaagaagt taaatctttc cgcttctctg ttataaaaat attcaaagtc
      661 catgcaagat cacctccctt cttaaaaatt tgcaaagaaa aagacgatag tttttcttct
      721 atcgcctttg gtaaccattt ttatgaaatt ttttaaagtt aaaaatataa tttataatac
      781 tatcttcttc cattttctga ttttagttct gaaagttcca aaaggtgcaa ccgtatttac
      841 atgaataaac ttatacactt cccaagtcgc tgttttagtc gcttcatcag cccactttct
      901 catatgcggt tcaaataatt cttcctcact caacgaatca atcattgcag agatagaatt
      961 aatattttca tttaattttg ctttcaactc ttgcagagat aaatgagcgt aggtatctgt
     1021 gaaccactga tataattcac caagttgatt ccatttaaat ttatccgatg gtgtttttac
     1081 ttgaagcccc tttctttcat cttcttccca tttaagaacc aagttggtcc aaccaacctg
     1141 ataagcaagg ttttctgctg gagttctgtc aacttcatca gctctcttat cttttaaatt
     1201 ttctggaata ttatcaaatt ctaaaatata tttctcaaat gttttctcta tctcagcttt
     1261 tagttcttct ttattttcgt atgttcgcaa aaaatcacct tctttctgat ttatcaatcc
     1321 tttgatttaa aatgacctta tttttctatt tataccttct aagaacgcta taactgctgc
     1381 tccaaccatc ggtattccgt atgggcttaa taaaaaactt aataccaaag cttctatacc
     1441 aagtgataca tctttatatt atcatcacta attaagttaa acagaaacag acagaattat
     1501 tacatcctgt ctccctttat tgtttttctt cccagtcgtg gtaggcagcg tagagttgac
     1561 tcttattcca ctggtaaatc ttagctactt ccttaatagc ttgatttttc ttcatacctt
     1621 gctggatacg agcttggatt tctaagaaca agtcttcctc gtctttttct tccacatcct
     1681 gactggcacc ctcaacaatg agaagacatt cgcccttgag tggcgtttca gcaatgcttt
     1741 ctaataactc agagatagta cctcgttggt attcttcata gattttggtc aattccctga
     1801 ccaagacaac ggagcggtca ccgtagactt ctaacatatt ttccaacgtg tctgctacac
     1861 gatgaggtga ttcataaaaa atctgtgttt caggataatc ttttttcaag ccaaaaaatt
     1921 gcttctgctg acctgatttt ctcggtaaaa atccgtaaaa gatatgtggc tgtggcgcta
     1981 aaccactggc aatcaaggca gaaattcctg cagaggtacc tggaacagtc acaactgcaa
     2041 tttcttcctc aatagctgcc ttaactaaat catgaccagg gtctgaaatg ctaggcaaac
     2101 cggcatcaga gacctgagca atactttgcc ctgctttcaa gaaaccaatc aaatcaggaa
     2161 ttttttcctt ggcattgtgc tcatgaaaac tgatctgctt ggtggaaatg tcaaaatgct
     2221 tgagcaaaag ccctgtattg cgcgtatcct cagcagcaat ccagtccact tctttcaagg
     2281 tctggatagc acgaaaagtc atatcatcta gattgccaat cggcgttgcc actagataca
     2341 gcttgccata gggagattgc cccttaaaac ttttttgaat ttgcatgcct actccctgta
     2401 taacaactca tcacagaaca tacattcttc gtcctgctct cgacgttgtc cataaaaatc
     2461 attacatacg tgaaatccat cacggtaaat acgacggaca ctttcgcgaa catgcttggc
     2521 cttgacggga gcgtctgctt ccacctcacc caagcgttct cgcaacttac tattttccaa
     2581 gcgaagagct gtattttctt ctaccaagct cttgagattt ttcttgatgg cttccacatc
     2641 ggctaaagtt accaataatt gttgggaaaa atcatccagc gcgtcaaata attctttttt
     2701 gtccataaaa cagccctttc ctttctttat cattcatttt tgagtttata tttctttcaa
     2761 gaccagatat tccatggcat tttgaaagct gacattagct tgccacattt ttctagcttc
     2821 tagtaaatct tgtagaatca ctcttactct tacctgcaag aggtcctgcc cacagagaac
     2881 ttcaagaatc cgtaaaacct gatcctgttt ttccttatca tctgccaagt tggctaattt
     2941 ggcaacctgt agataacttt cttttttctt agctactaac caagtcagca ggcgttcact
     3001 ttcatcgacc aaggtccaaa aacttgcctg attagccaac ttttctgctt cagctcgcga
     3061 ttgactaaac ttagctaaaa gagtcgcttt tttcttaaca agtcccattt gttctaagag
     3121 taagataagt ttttcttctt gctttttaaa gtggaagatc tgagtccgac ttcggattgt
     3181 cggtaacatc ttttcctcat cgctagtcaa gaagaaaata taaacttcac tctggggttc
     3241 ttcgataacc ttgagcagag aattggctgc gttgggatgc attttatccg cttgctcgat
     3301 gataaagacc tgttgctggc tttcaatccc tgcttgagaa aactgtccca ccaattcccg
     3361 aatgcgttct gtcttgatga cctgattgac tggcttaatc aaggtgacat ctggaaactc
     3421 ttcctgttca atcagcttgc aacttcggca tttctcacat ggtaagacgc caactttatc
     3481 cgtacaaaag aggctcttag ctaaaaattg cgccatttcc aagcttccaa agaaacctga
     3541 aaagagatag gcgtgattga gctggtcttg ttctaagata cggacaaaac ggtcaaactg
     3601 agctggttgc caagccttta gttgatcttg tttcatttgg ccaagcccat tccgtcaaac
     3661 aagacagcct tggtagtttc cacaacttgc tccaaaggga gactagcatc aatcttgaca
     3721 atgcgatttc cttctttttc caggagagaa aggtagcctt gacgaacttt tttatgcaag
     3781 tccaaccctt ccaaatccaa acgattaacc tcgcggtcac tattagcagc aatacgagcc
     3841 agcccttctt ccacctcgat gtcaaaatag agtgtcaaat cgggtttgag gccatctgtc
     3901 gcaaactgat tgagccagtc aatggcttca atatctaagc cacgaccaaa tccctgatag
     3961 gcaacagaac tatcgataaa acgatccatg atgaccaact tgccagcttc aagggctgga
     4021 agaacttttt ccaccaaatg ctgtctgcga ctggcaatat agagaagtag ctctgtttta
     4081 gcatccatct gagtatgact tggatccaaa atcacttccc gaatcttctc cccaatcaag
     4141 actccgccag gttcacgggt cgtcagcacc tttactcctt tttcctctaa aattggtagc
     4201 agagcctcta aaacactggt cttgcctgct ccctctggtc cctcaagaga gactaaaaat
     4261 ccttttgaca tgtctaactc atttcttttt tactacttct attctatcaa aaaaataggg
     4321 gtttgtgaca atctttttgt cttctcattt catactcaat gaaaatcaaa gagcaaacta
     4381 ggaagctagc cgcaggctgt acttgagtac ggcaaggtga agctgacgca gtttgaattt
     4441 gattttcgaa gagtatcaac caccataaaa gaggcagata aaactacctc ttatttacct
     4501 agttcttgtg ttcgtttata ggcttgatga actgcctcca tgactatgcc tcgaaaagca
     4561 tgcgcttcta agcttgctac gccagcaata gtcgaaccgc ctggactaca aacttgatct
     4621 ttcaaaactc caggatgttg ctggctttct aggaccaatt gcccagctcc taccacagtt
     4681 tgggctgcca ttttcaaggc tgtttctcgt ggtaatcccg tctgaacacc tgcatctgcc
     4741 aaggcctcaa taaagagata gacaaaggct ggtccacagc ctgcaagacc tgtcgctgca
     4801 ttgatcaagc tttctcctaa ttcaaccaag agaccagcct tggataaaag ctgacaaaag
     4861 agctcactgt cctcagccct gcaattagga gacaaggcat aactaatcac tccttgcccg
     4921 atagaagcag gggtattagg catcatacga ataattcggt gttgacttgg gataagactt
     4981 gctagttttt ctaaggtcaa tccagctgcc atcgaaatca aaagaagact ttctcttttt
     5041 tcaaggatgg tctggtattg agaaagcagt tcagaaaact gagcaggctt aactcctaga
     5101 aaaatcacat ctgcttctgc aaacatttct tcattgctgg aagcctgacc accaaagtct
     5161 gcaatgaaag catctacctt agcttgacta cgattggcaa ggagaatctc atctgacgtc
     5221 ctagtctgca agacagattt tgccaagcta gcacccatat tccccaaacc gataaatcca
     5281 atcttcatct cttactccct tatctgccca tcaccagcaa ccacatactt gtagctggtc
     5341 aactctttca agcccattgg accacgcgcg tgcaatttct gagtagaaat ccccatttca
     5401 caaccaagac caaattgtcc tccatctgtg aaacgagttg aggcattaac atacaccgct
     5461 gcagagtcca cttgatctgt aaagtatgct gcagcttcag cattttccgt cacaatagca
     5521 tccgaatgat gggtgctgtg ggattcaatg tgcgcaaccg cttcttctaa actgctcaca
     5581 accttaacag caaggacata gtctaaaaac tcggtgtcaa agtcttgggt ctcagctgct
     5641 tgacctgaaa caaactggct tgctttgcta tccaagcgga attgaattgg ttccagtcca
     5701 gcttccttac gctctgcaac cagcatttga tccaagcgag gaaggatgct tgctgccttg
     5761 ttttcatgaa ccagcagaac ctccatggca ttacaaacag aaggacgact ggttttagca
     5821 ttgttgatga tagacagcgc cttgtcttcg tctgcatcct tatccacata gacatggaca
     5881 atcccagtcc ctgtctcgat aacaggtaca atcgcattct caaccactgc attgatcaag
     5941 ccagctcctc cacgaggaat gagaaggtct agatagccct tggccttcat catagcataa
     6001 ctactttcac ggctagtatc ctccaccagt tgaatcacat ttggatgaat agtagtcgtc
     6061 tccaagccct tcttcaaggc tgtgacaatg gcatgggttg tttgataggc atccttacca
     6121 ctacgaagaa caaccgcatt tccactctta agagtcaaag cagccgcatc agacgtcaca
     6181 tttggacggc tttcatagat aataccgatg acacccatag ctacacgttt ttttgtgata
     6241 accaaaccat tttcaagctg acttgtttct aaaacttcac cgattggatc tggtaaggca
     6301 accacttcac gaattcctct tgccatcgct tctatacgat ctgcatccaa ataaagacga
     6361 tccaacatca catctgagat tttcccctta gccgctgcca tatcgagggc attagccgct
     6421 aaaatttcct cagtagcagc cactaagtga tcagccatgg ctagcaaggc ttggtttttc
     6481 acttcttcac tagctgtgtt aatcgatttt ttaacagcct gtacctgttc aaattgttct
     6541 tgtctactca ccatagttta cctctaaaat tctgtaaaaa gtagttggat ttcaggagta
     6601 atggaaatcc agtcgtcacg gtaaatcaag acacccttgg ctttttgaga acgcaacata
     6661 tcctccaaag cagatgctcc aaattgcacg cgtccttttc caagtgattt tccactttcc
     6721 ttgtcaaata ctgtcacgat atcaccgtaa gaaaaggctc cttctgcttc aacgatacca
     6781 gataagagaa gactctttcc atgttgagag agagcttccg cagccccttt atcaacccaa
     6841 atagaacctt gactctgagc atagaaggca agccattgtt tctgggtacg aagccccttc
     6901 tcttgagcaa caaagtaaga accatcctcg gtctcctctg ccgcctcaat catggaatct
     6961 gatttcaagg atgagcagat ataaacagga actcctgatt ccgtcgcgat agttgcagcc
     7021 ttgattttgg ttaacatacc cccagttccg tttgacgaac cagctccacc agacatatca
     7081 ataatctcac gattgatggt ctcgattctc tccaagcgtt tggctcttgg atctgaatta
     7141 ggatttccag tatagagacc gtccacatct gtcaagaaaa ctaaaaggtc tgcttggacc
     7201 atcgccgcta cttgagcact tagagtgtca ttgtccccaa ccttgagctc atcaataacg
     7261 acactatcat tctcattgat gataggaatt gccccacggt tgagcaaaac cgacaaagcc
     7321 tgatgggcat ttttataacg acgcttatcc acaaagtcat cttgggtcag caagatttgt
     7381 gcagaaacga tttgacgcaa gagaagattg gttgtatatt cttccaacaa aagcccctgc
     7441 cctaccgctg ctgaagcctg tttatcagca attttagtcg gacgcttttt aaatcctaag
     7501 gctccaaaac cagccgcaat ggcacctgaa gacaccaaaa tcaactcatg accagcctcg
     7561 tgcagcatag ccaactgctg ggtaatatcc tttaccttac tacgtgataa acttccatcc
     7621 tcatttgtca gagaagaagt acccacctta aagacaatcc gtttgtattt catagtctca
     7681 ctccgattat tcatatttat ccattataac atgaataaca gaaaatagaa aagagttgat
     7741 aggaaaaaga aggccctaaa accttctttt ctactactgt tctgattccg atttgtttac
     7801 actcgtttca gagctttgtg aagttgagga tgtcaaatct tgactagttg aagaatttgt
     7861 aacactttca tgttgactcg tttctttatt ttcaagatcc tttttcacta cttctttgga
     7921 ttcttttatt tctgaatgac ttgtagtttt aattgtagca gatttctcga tcggaacatc
     7981 cactaaccag gcaccacttg aatccacagt atagccttct ggtgtcttac cattcacaag
     8041 taattgacca ttttctttca agaagtacca tttatccttg tctttaatcc aacctatagc
     8101 tcgtgaacca tctgtcttgt agaaatacca atcatttgcc tttttaagcc agccttgctt
     8161 catagctcct gattcttcta gatagtaatg atgtccagca acttctatct cacctgtctt
     8221 catgatacca gtagaatcca tatagtacca ggcttcttta tcttttaccc agcccgtttt
     8281 catttcccct gatggagcaa agtaatacca ttgcccctta tattgaagcc aacctgtctt
     8341 catagagcca tcaacatcca aataatacca ctgctcttta tcttgaatcc aaccaatttc
     8401 catctggttt tctttgttaa aataatacca gattccagcg attttcttcc aatttttagc
     8461 agcaacacca gagtctgtca aatagaacca acgattgttc cattttttcc attgattctg
     8521 taataagata cccgtttggt taaagtaata ccattcaccc ttaatttcat tccaaccgac
     8581 agcatattct cctgtagaat caggcgcttg ataccaccag tttccatatg aactcttatg
     8641 ccaaccagct tgaaaacttg gaatcggctt gtaggaagtt gaaatgttta ctaaaccgtc
     8701 ttgtcgaata tcaaaaactg tcgcatcata gtctttgctg gctgcgttga ttctctcaat
     8761 tcctcgttct ttgatccaat taacatactc actatcaaca ccatttttcc aaggtagact
     8821 atccgaagtt tgaacaatca aactcggact caaattttta atgaaatcct tggtatttga
     8881 tttgttggta tcatggtgat gattaaactt catcaaatca acttttccaa tgagaggacc
     8941 atacttgtct tctgctccat gaacattatc taagtcgccc ccaaggtaaa ttttcttgcc
     9001 attgactttt accacactaa tcaaggaatt ggaattatca tcccaaattt tctttaattc
     9061 acccgatgaa tcggtttcat tttcatagtt atagagctca atatccatgt ccccaaactg
     9121 aaaatgagca tccccttgtg tgatattttg aataactgaa acaccttttt ctgaagcagt
     9181 ctgtaaaacc ttatcataac cgtacagatt atcccataga cgttcagaat tagtaatacg
     9241 attatcacta tattttttaa gatagactcg gtcaactgga taggtagaca gtaattcatc
     9301 aacatttcca atatgatcac tgtgggtatg ggtcaccaaa ataaaatcaa gtttttggac
     9361 acccaattcc ttcaaacgac gaaagacacg gtctgttaga acatgcttat aagacgtttc
     9421 aattccttct ctccatggat agcgagaatc acttccatct gggaaatcat aatcttctcc
     9481 tgtatccacc atggcaaaat gtccattgct ttcaagaata atcgcatcac tgccaccttc
     9541 ttgaacattg ataaagtgga ttttatttcc tgaactttct tgagcctgaa cattcccata
     9601 ccatgacaaa cctaaaaaag cgcctacaag tgctaaacta gttaatttct ttttcattct
     9661 tactttctca atctctccaa ggtttcctta aaaatctctg ggatatctgc tttaaattcc
     9721 aaggtcttac ctgttctcgg atgagtaaaa cctaaagtct tggcatgaag aaattgtcca
     9781 tgtcctttca aagtcttgcg aggaccatag acctcatcac cagcgactga atggccgata
     9841 taagccatgt ggacacggat ttgatgagtg cgccctgtct ccagttgcaa ctctactaag
     9901 ctataatcgc caaagcgttc caagacgtga aaacgcgtca ctgcaggctt ccctttagca
     9961 gttacagcct gtttcttacg gtctttttca ctccggccaa tcggcgcttc aattacacca
    10021 cgatcattag gcagatttcc atgaacaatc gcccaatatt tgcggagaga ctttttatcc
    10081 ttgagttctt gggcaagtgc tagatgcgca tcatcgtttt tagcaatcat gagaagacct
    10141 gacgtatcct tatcaatacg gtgaacaatc cctggacgca gaaccccatt gatacccgac
    10201 aagtccttaa tatgatacat gagggcattt actagggttc cactggtatg accagcactc
    10261 gggtgcacaa ccattccctg aggtttgtta acgacagcca catcctcatc ttggtagact
    10321 atttctagcg gaagatcctc agccacatac tctaatacct ctggttctgg cacatggtaa
    10381 gtgacgacat caccctcttg gactgtgtat ttagctttct tgacttgacc attgaccaag
    10441 acctggcctg atttaatttg ttcattcgcg agactacgtg ataattctga caaagctgac
    10501 aaagccttat ccaaacgcag accaccagtt tcaattttaa tttccattta tttcctcttt
    10561 tagcattgca atcaataaaa taatcactcc aaccgtcaga tagctatctg ccacattgaa
    10621 aattgcaaag ttgataaagt caaggtggaa catatccaca acaaagccct gactgaccct
    10681 gtcaataaag tttccaagac cacccgcgat tattagagtc aaacccaaga ccatccagaa
    10741 tgagtcctcc atgtgtttat gtaaatacca aatggcacct atcacgacaa ccagagtaat
    10801 gacagcgaat aacagctgct gatcttgtaa gatagaaaag gctgcacctc gattttgcag
    10861 gtaggtcaag ctaacgaaat tgggaatcca ggagcgcact tcacccagtg gaatctgctg
    10921 gacgatatag gatttgacca actgatccag cccaattaaa agcagtacaa tgactgccac
    10981 tattgctctt tttttcatga tttcctcttt tgatcaaaat attcttgcat gacttctacg
    11041 aagagagtcc cagcttgact aagctccact tcttcacgtt taacatagac catgcggtta
    11101 tctaggttat ccttgagacg aataactgta ataccattaa cactgtcact atctaaaaat
    11161 ccagaacctg tcgcataggc gtccgtccgc tccaaaatac cattcaaggt ggcacggtct
    11221 gtcacattaa acatctgtga gctagcgctg gtatcgacaa agttctctga ataataaagg
    11281 tactcgtctt tctcttgagt gaaacgaacc gttggtaaat ccgctaaatc ctccatgact
    11341 aattcctctt tctgggctaa aggatgaccc tcacggagat aaatatgggt atggaaagga
    11401 atcaattcga tgacctccag acctaatttt tcaacccgtt gcataatccc ctttttattt
    11461 tgattgttga ggtagataat cccaatctca ctatgccctt gcgccacttc atctaatatt
    11521 tgaacagtag ttgattcaaa aatacggaag ttcttatagt caggatagcg ctctgaaaag
    11581 gccgtaatag ttggtggcaa gaagtcatag tgctggctag caacagaaaa ttcatctttt
    11641 tcttcttcag gattggcata ctgattttga aaaatatcaa atcctttaac caattcttgc
    11701 gatttttcat agaattccat cccacgacgg gtcaagaaag tccctgagct ggtccgacgg
    11761 aaaatcttaa aacccaactc tttttccaaa tcacgaacag aaatagacag actcggctga
    11821 ctaacataca tcttttcagc agcttcacgg aaagtaccac tattggcaat ggccacaaca
    11881 tagcgtaatt gttgaatgtt catcttctac ccctaacttc tttatctttt cattatacca
    11941 tattttagaa gttttccaaa aaggaaaaaa gaacatccta ttcttcttca ctatctgcct
    12001 ttctcaagcc aaccttattt tcaaaatcaa ttcaaaaaaa taagtggcta cacaccactt
    12061 cagtatcgga aagaaaaacg ttgactattt gtgaaaaaag aaaatgctgg aaagttccga
    12121 cattatttta gtaagctaac ttcctgaaaa taggagcaac cacacgtccc agaaggcagt
    12181 gatattaatg agaatatgaa ctagtattgg atagtagaga tttttagtca tgcgatacaa
    12241 tagagctaaa ataagacctc cactagcata aatgaaaaaa gcaagaggag ttaaagcaaa
    12301 attgatatga atataaccga aaataatagc agaaagcaaa acatctccgt accaaggtga
    12361 gtttttgaaa aaggttgtca taagcacacc tcgataaatc aattcctcag caataggggc
    12421 gatgaagcaa acgatgagca agaaataagg gaactcctgt ctccccatca tttctaccgt
    12481 ttcattcaaa gaaatttgat ttgaaggcgg ggatatgaaa tacgaaaaga ggaagtcaga
    12541 catatatgaa atgatgtagc ccagtaaaag gtagatgaag tacctcagct gccacttgaa
    12601 atgaaaaatt ttctttcctg caaaaaccag tagatagatg accgctaaga aaagaactcc
    12661 gctctccatc aaaagcagaa tctgaaaaaa ttcacgactt gctggtagat agggctttgc
    12721 gaggtgattg aaaactctcc aaaaccaagt tgatttgtaa aaaattaagg acaatgctag
    12781 taaaatttga atagcccgtt ttttcatatt aaatcctctg ttttctcccc ttgtttcttc
    12841 atattcctaa taaattttac ttaaaatctc gcagcacttc ctttgcaaag atgattacct
    12901 cctccaatat atcctaaatc atcggttcct ctgggacaaa atccatgaac cggcatagtt
    12961 aatactggtt ccatttgcca aggataataa ccattaggtt ctttaccata gggatctgct
    13021 ccaccttgta tcagctctaa ttcttcattt gttagattta tattttttgt cattaaaatc
    13081 atgatatatt tcctccgtta ttgtttagat tagttgagta atctgctact catacctact
    13141 tacaaaaaaa actattatat taagttggtt ttttaatttg tctagttgca acattgacaa
    13201 acatagtata gcatatcttt gccaaatctc ctcttcaaat catgaattgt catcaaaaca
    13261 tcttaaacta taaaatcaat tagtctcaag ctttctatca atttcttctc caaaatatgc
    13321 tataataata gcaaaagata aagaaggaag acctatgatt aaactactag ccttggatat
    13381 ggatggaacc ctcctcaatg aagccaagga aatcccacag gctcacatcg ctgctattca
    13441 ccaagccatt gaaaaaggtg tcaaactggt cctctgtacg ggtcgccccc ttttcggtgt
    13501 cctcccctac tacaaaaaac tgggactcga cctccagaac gaatatgtga ttgttaacaa
    13561 cggttgttca actcaccaga ctagcgactg gggcttggtt gactggcaag aactgagtcc
    13621 agctgacatc gaatacctct atgaccttgc tgaaaagagt gatgttcagt tgacactttt
    13681 tgacgagtca cattattttg ttctcggtgg caagcccaat caagttattg aaaatgatgc
    13741 taaactagta ttttcagacc tgactgaaat ttctcttgaa gaagcgacta gtggaaagtt
    13801 ccggatgttc caaggtatgt ttttaggaac aaaagaacaa acagacgatt ttgagcagcg
    13861 ttttgctgaa gagctttgcc aacgattcag tggagttcgt tcgcagcctg tcatttatga
    13921 agcaatgcca cttggaacga caaaggctac tgctctttca cgacttgctg agattttgaa
    13981 gattgattcc tcagagatta tggccatggg cgatgctaat aacgatatcg aaatgctcca
    14041 gtttgcaggg cttgggattg caatgggaaa tgccagcgat tatgtcaaat ctcttgcgga
    14101 tgccgttacc tcaagcaacg aagaagacgg cgttgcgcgt gctattgaga aatatattct
    14161 ataaaaaaag aaaagcaaat agacagaagt tactgctatt tgcttttttg ctaatattta
    14221 aaatacggac taatcaatag acaagaatag cgaatcataa aaatcgattt actagatgcc
    14281 atagtatctt atagttgcta ataagaagtt agtctagcag aatgaatctc tcatttctcc
    14341 cacactaatc tgtaatttgt ctatacattt ctggtcttct atctcgaaac aagccccagt
    14401 ttagacgttc acttgctccc ttgtctaggt cataagtagc taacagaaca gcttcttctt
    14461 gtctttcagc tcgttctaga atagctcctg tttcatccgt cataaaggag gaaccgtaga
    14521 agtcaagact ggaactctgt ccgccatttt cctcactagg agtaacctcc tctaaaccat
    14581 aacgattggc tgcgatgact ggaacaatat tcgctgctgc gtgcccttgc atagtacgtt
    14641 gccagtgacc acaactatct gtatccaaaa ttggctctga accgatagct gtaggataaa
    14701 agagcaattc agcaccattc aatgcaagac agcgggctgt ttcagggaac cattgatccc
    14761 aacagatacc gataccaatc ttagcatagc gagtattcca gaccttgaaa ccagtgttac
    14821 caggcgtgaa atagaatttt tcttgataat aatggtcatc tggtatatgg gtctttcgat
    14881 aaacgcccag cacttcccca tctgcatcaa tgacggcaat agagttatac aagacattac
    14941 catctttttc atagaaactg attggtaaaa caacttgtag ttccttagca atcaccttaa
    15001 aatgctgaat ggcagtattt tccgctacag attgggcata ctggtagtag tcatactgac
    15061 gttcctgaca gaaataggga tgttcaaaca actcgggcaa gagaataatt tgggctcctt
    15121 gctcagcagc ctgacgtact aaacgctctg cggtttggat atttgttgcc acatccttag
    15181 cgcattgcat ctgaatggtt gcaactctta catttctcat ctttttctcc tattctggaa
    15241 tttgttgggt gatacagtgg atattgccac cacctaagag aatatctctg gctggtattc
    15301 cgacaacttt acggtctggg aaacacttgc tgaggatatc taaggccact tggtcgttta
    15361 catcctcaaa ctgtggaacc aagacagcct tgttggcgat ataaaagttt acgtaggaag
    15421 ctgctagtcg ttcacctgcg tatcgctctt cttctccttc ttcatagatg tagcctggca
    15481 aatcttcttc tgtcacaact tgtcgaactg cagggatagg caatttatga atggtgaagt
    15541 gacaaccttt tgcatctgtt tcctgttcta agagttcgag atctgctttt gacatggcat
    15601 actggggatc attttcgtca tctgtccaag ccaaaacaac ctcagcagga ccaacaaagg
    15661 cagcaacatt atcgacgtgt tcattggttt catcctgata aataccataa ggaagccaaa
    15721 taactttttc agcaccaaga ctttctaata atgtgttttc aatctcctct ttagtcaagt
    15781 taggattgcg accaggacta agcaagcaac tttcagttac gagaatagtt ccttgaccat
    15841 cgctatggat tgcacctcct tccagtacaa aaggtttagc atcatagaca ggcctttcca
    15901 aggcctcagc aaaacgactg gctacttggt catcctcttc ataatcttga taaagaccat
    15961 cataggtgcc tccccaagca ttgaaggccc aatccacggc taatttctta cctttatcat
    16021 tgacgagaat ggttgggcca gtatcacgcg cccaggcatc attggtggga atgtctaaat
    16081 aaacaacctt gtccccaaga taggattggg cttcagatag ataggcctgc tccaccaaaa
    16141 gatagactct ttccccttct gctatagtct cgatgatctg agtaaatgct cttttagcat
    16201 cctttccttg aaaaggccat gatcctggtc gagtcggcca tatcatgagg gtaccatgat
    16261 ggggttcgta ctctgctggc atgtgatagc ctaatttttt tggactgtcc atcatgataa
    16321 tctcccttta aagtcttgat agccaaaagc tttgagtaag ctacagtctc cctgttcgtc
    16381 catgagatag agacttggca atccaatacc attaaaggta ttatttttga caaaagaata
    16441 aatggccatg tcttgaaaat aaagtctgtc tccgatttgg actggatttt caaaactata
    16501 atcaccaatc acatcgcccg tcagacaggt attagaagaa agtctgtagg tatgggcttt
    16561 ttcctgtgcc tcaaagccat ttctcaaagg tggacgatag ggcatctcaa gtacatcagg
    16621 catatggcag gtcgcagagg cgtctaaaac caagatttcc ataccgtttt ctacaatatc
    16681 taatacctca gttgctaaat aacccgcatt aagcgcaatg gcttcaccag gctcgatata
    16741 gatttcaaga ttgtaagttt ttcggatacg cttgatttct gaaatcagca aatccacatc
    16801 gtaaccttct cttgtaatat gatgaccacc acccatattg agccatttta cctcatgtaa
    16861 gtagggacca aactgttctt ctactgcttt caaagttgtt tgtaaatcat ctgctccctg
    16921 ctcgcaaagg gtatgaaaat gaagtccgtc aaccaaatct agcaaatcac tcggaatctt
    16981 gtctatagta actccaaagc gagaacctgg tgcacaaggg tcatagagcg cgtgatctcc
    17041 ttgagttgaa cactgagggt tgaggcgcaa accaacactg acaccagcct ctcgacaacg
    17101 agccccatgc ttacgcaact gtctctctga gttaaagacg atatggtctg ttatcccaag
    17161 caattcctcc aagtctgcat ccttgaaagc aggcgcaaat acatggactt caccaggaaa
    17221 ttcttccctt gccaatttgg cctcatagag tccactagct gtcgtacctg atagatactg
    17281 gctaatcaag ggataagttt tgtagaggga atatgccttc tgggcaagca agaccttgca
    17341 accgacctct tcttgtacat attgtagaat gcggcaatta gcttctaact tggccaagtc
    17401 aataacatag gctggtgttg gtacttgttc taacttcatt agtccaccat ttgtggattt
    17461 tcaaccacaa cccatggcaa accatactca ttcaaagctt ccatgaatgg atctggatct
    17521 aactcctcaa ggttatacac tccagcttgt ttccaagttc cgttcatgac taattttgtc
    17581 ccaatcatgg ctggaacgcc tgtcgtgtat gaaattgctt gtgacccgac ttctgcatag
    17641 cactcttgat ggtcgcaaac attgtagatg tagatagtct tttcaacgcc atctttgaca
    17701 cctgtaaaga tacatccaat attggtttta cctacagtac gtgggccaag gctagcagga
    17761 tctggaagca aggctttcaa aaattgaatt ggaacaattt cttggccgtt aaagttaatg
    17821 gtatccgtac gaaggagtcc aacattttca agacatttca tgtgcgtcaa gtaagattga
    17881 ccaaaagtca taaagaaacg aatgcgtttg acacctggaa tgttcttggc caatgattcg
    17941 atttcttcat ggtgaaggag atacatatct ttttgtccaa cttgagggaa atcatactca
    18001 cgcttgatag acatagcttc gacttcgacc catttcccat cttcccagta agaacctggc
    18061 gcagaaacct cacggagatt aatttctgga ttaaagttgg ttgcaaatgg ataaccgtgg
    18121 tcaccgccat tacagtctaa aatgtcgata taatggattt catcaaaata gtgtttgagg
    18181 gcataagctg aaaagacact agttacacct gggtcaaagc cagaaccaag aagagcagtc
    18241 aagcctgctt ctttgaattt ctcttgataa gcccactgcc atgagtagtc aaagtaggct
    18301 gtaaaaccaa gttccttaca acgtttttcg tagatagcac gccactcagg gtcttctgtg
    18361 tcttctgctt cgtagttggc tgtatcgata tagtgaacac ctgttgccaa acaagcatcc
    18421 ataatggtta aatcttgata aggcagagct acattcaaaa cagcttctgg tttgtagctt
    18481 tcaatcaggg caatcacttc ttcaaccttg tcagcatcaa gtgctgcagt ttcaatttta
    18541 gtacttgttt tgccttctag cttcgctttc aagtcatcgc attttgactt ggtacggcta
    18601 gcaatcataa tctctgtaaa tgtttcgcta tcttgacaaa tctttgaaat agcaacttgg
    18661 gcaacgcccc cacaaccaat aactagtaaa cgactcattt ttttccttcc tcttcttcta
    18721 aaatgtcctc aacatacttg ggcaacataa aggatcccac gtgtaagttt gcagtgtagt
    18781 attctgtgaa aagctggcgt tttttccaac cttccttgtc aaaatctttg acagggtggt
    18841 attttttcga tgcaaatcca aacaaccaat agccagctgg gctagttgga atatgggcct
    18901 gataaacccg actgattgga aaggattgat tgaccttgcg gtgcatgctt cggcaggccg
    18961 actcatcctc gtcaaagaag ggactcccat gctggtaaat catgatgccg tcttccttca
    19021 gagctcgata actattgccg tagaattcct tggtaaagag tccttccgta tggccaaatg
    19081 gatctgtcgc atcgttgatg ataatatcgt aatcatcttc gcagtttcgc aaaaagcgta
    19141 gcccattttg gtagtaaatg gtaacacgag gatcatctag ccctgcagca aagtctggga
    19201 aatactcacg acagacctcg accaacatct catccggttc cacgatatcg atttgttcca
    19261 gttcaggata gagtgttaat acttgggcaa caccgccgtc accaccccca ataaccaata
    19321 ctttctttgg atttgggtgg acagccatgg gaacgtgaac ggtcatttca ttgtagacga
    19381 aatcatccgc atctgagaac aagacatggc catttaaaat cagtattttc ccaaaagctg
    19441 gcgtatccaa gacttcgata tcctgccatt cactttttcc agcgtaaagt tgcttggctg
    19501 ttctcagaga caatttgaca tctggagtat gaacttcaga aaaccataaa tccatctatt
    19561 tctccttata ttatatttag cgcagttagc tactgccaaa gcccaagtgg tatacttgga
    19621 ataagccact gtggattagt ttattccctc caatcgcttg acgatttccg aaaggctcta
    19681 accacagttt tttgtttcaa ttggtaatga gtttgataac gcatagacgt tttatctcgt
    19741 ctaaggtaac aaggcaaaaa attcgtggat aaccaagtag acttgaaata ctacatctgg
    19801 aggtactccc atgctttatg tgggcattga tgtcgctaaa aataaacacg atgttacagc
    19861 cttgaatgtt ccaggaaaaa ctgttcttaa accactcact ttttcaaata ataaagctgg
    19921 ttttgaactc ttagatctgt ctcttcgaca actcaaccaa gactgtctca tcgctcttga
    19981 aaataccgga cattatgcct ttaatctact gaacttcctg catgaacaag gatataaagt
    20041 ttacacctgc aatcctttgc tcatcaagga atttgccaaa tcattatcac ttcgcaagac
    20101 taaaacggat aagaaagacg ctcatggcat cgctcttaaa cttctttctg accccaatcg
    20161 tgaacaattt caacacgata atcggcaagt agaactaaaa atactggcta gacatattca
    20221 tcgtctcaag aaaaacagtc tgattggaaa gtacaataca ctcgttgtct tgatatcatc
    20281 tttcctgagt tggataaaat cgttggaaag cattcagaat atacctacca actcttgaca
    20341 cgctacccta atcctcagaa aaggattgag gcaggatttg ataagctgat agaaattaag
    20401 cgattgaccg cttctaattc aagggctttt tgccgtgctc taaaatcatc gccaaatcat
    20461 caaattgaaa taagaaatag tttagataaa actattgact tttcttatag tttgtctttc
    20521 tcttaataac gttgatatga ttgacctctg gatcttccgt cccttggagg gagcaaccac
    20581 gttccttggc gaattggata tagtctacaa tttctcgtgt aatgcgttca ccaggagcca
    20641 agataggaat ccctggagga tagcacatga caaattctcc acagacctgt ccaacagact
    20701 catctaaggt caaacttttt ctctctgaat agaaggcttc ttgtggagac agcaccaact
    20761 cgggctgaat atattctcca gctattaagt ccttcccatc tcgtgaatag agtctcttaa
    20821 tatcagccag agcaccaacc aagcgctcga tgtcttggat gcggtcgccg atggaaatat
    20881 aggccaagat attgccgata tcaccaaact cgatctgaat gtcgtattcg tctcgcaaga
    20941 ggtcataaac ctcgatacct gttaagccta ttccctgagt gtaaactgac aacttggtta
    21001 catcaaaatc acagaccgac acaccatcta ttaactcttt tgagtaagca tagtaaccgc
    21061 caatggcatt gatttcatga cgagcgtact cggatagctc aatgacttcc tcaaacgact
    21121 ctttaccacg aagggccaag ttgcgacgtg aaatatccaa actagccatc aataagtaag
    21181 aggcagatgt agactgggtc aggtttataa tctgacgaac gtattcggga ttcatctgct
    21241 ccccgattaa aagaagcgaa ctttgtgtca aactcccacc agacttatgc atggaaactg
    21301 ctgccatatc agctcctgca tccatagcag aaattggaag tttaccagtg aaatgcaaat
    21361 gcgctccatg ggcttcatct actaaaacca tcatgccagc ttcatgagcc atttctgtca
    21421 acccctttag gtctgaacag ataccgtagt aagtaggatt gttgattagg atagccttag
    21481 catctggatg gtcctttatg gcctgtgcta ctcggtcatt ttcaagacct aaagcgatac
    21541 caatcttagg atctacactc atctcgatat agatgggaat ggcaccacat agaaccaacg
    21601 cattgatagc agatttatgg acatttcgtg gcagaataat cttatctcct gccttgcagg
    21661 ttgccagaat catagtctgc accgatgaag ttgttccacc aatcattaga aaggcatggc
    21721 tagctccaaa agcatctgca gccagctcct ctgcatcacg aataatcgaa ataggatggc
    21781 ctaaattatc caagggtttc atcgaattga catcaatgcc tacacatttt tctcctaaga
    21841 gttcgacaag ttctggattt ccccgtccac gcttgtgacc tggaacatca aagggaacaa
    21901 tccttttctt gcgtaacttc accaaggcct cataaattgg ggcttggttt tgatctaact
    21961 ctttcaaaac atactccttt caatattttt aggaccttat gaaaactaag gaactaaagg
    22021 ttgactcatg aaaaaagagc aggttttcac ctgctctgca atcttctgac gtgtttattt
    22081 tggtttctgt tgagtatgtc tgttcccgat gtttcctaac tctctagtag caaatattac
    22141 gtactttatt gatcgtttca caagatgacg tgtgctttca ccacactaaa aatttatgaa
    22201 ttaggacaag tgtcctaaca tcaacttata aaagtaggct tttaacccta tcaataatgt
    22261 ggcttttcaa ccacgcttcg gcattcaacc ctgcctgtcc gtaggcattt tttactcggg
    22321 tttatatttg ctagaaaaca tcatctcatt ttctaagctt tattactata tcatgttttt
    22381 aagaacttgt aaagtatttt ttgataaaaa acaaaaatat aatagattga aactagaata
    22441 gtacacttct gcttctaaaa cattattaga aatagatttt actgtcctga tcgatttgtt
    22501 ctgttcttgt ttcattttac tatatgttcg taaatgaaag ttctataatg aagttagcca
    22561 cccagccctc ctaaaaatta gatggttcaa ctagctgata gctcttgtag gcataagaaa
    22621 acacctctgt gttatacttg ttgttcaacc acaaacacaa gaaaggcaca gagatgcaag
    22681 acaattatac tacaaaagcc aaacatttga caatcgatag ccgtcgctta atcgaaagat
    22741 ggaaaaaaga agggaaatca aatagagaaa ttgcctctct gcttggaaaa gttcctcaaa
    22801 ctatccacac tgaaatcaag cgtgggacag tccgacaatg tcttggaaaa gggcgcttca
    22861 aagaggttta ttctgccgac tatgctcaac agtcttatga aaacaatcgc aagcgctcgg
    22921 tcaagaaatc aagcttgaca aaggaactaa aggaaaagat tctccactat cataaccaaa
    22981 aatttttgcc tgaaatgatg gttatggcta aaggggttaa cgtgggaatt tcaaccattt
    23041 actattggat tcatcatgga aaattggggt aaagcaagca ggatctgctt taccctagaa
    23101 aaggaaaagc gcttaagaaa caggccagca ccaactttaa acctgctggt caatccatcg
    23161 aacagcggcc tgaagctatc aattttcgct tggagaatgg gcattatgag attgatacgg
    23221 ttctacttac gagagcgaaa aactactgct tgcttgtctt gacggatcga aaaagtagac
    23281 atcagatcat ccgattgatt ccaaataaaa gtgctgaggt ggtcaatcag gctctaaaac
    23341 tcatcttaaa acaacacaag attctttcca tcacggcaga taatggaacg gaattcaatc
    23401 gcttgtctaa tgtattttct gaggagcaca tctattatgc gcacccctat gcctcttggg
    23461 aaaggggaac taatgagaat cacaacaggc tcattcatag atggttacct aagggaacca
    23521 agaaaatgac tcccaaagaa gtcgcattca tcgaaaagtg gattaacaac tatcctaaaa
    23581 aatgcttgaa ctacaagtca cccagagaag acttcttgat ggctaacttg aacttgaaat
    23641 ttagcgtcag aaacaaatca cgaaatcgat tcaaattttg caggtcgttt aaatatcctg
    23701 cgcgcaggtg ttcttggtgc taacgatgga attatttcca ttgctggtgt ggttatcggg
    23761 gttgccagtg ccacgaccaa tatctggatt atctttttat caggatttgc ggctatctta
    23821 gctggtgcct tttcaatggc tggtggagaa tatgtatccg tttcaactcc aaaagatacc
    23881 gaggaagctg ccgtttcgcg agaaaaactc ttgttagacc aagataggga actagccaaa
    23941 aaatccctct atgctgctta tatccaaaat ggagaatgca aaacttctgc ccaactcttg
    24001 accaataaga tctttcttaa aaatccactc aaggctctgg tagaggaaaa atatgggatt
    24061 gagtatgaag aatttaccaa tccttggcac gctgccattt ctagcttcgt tgcctttttc
    24121 cttagaagtt tgcctccaat gctgtcagtg accatattcc caagtgaata tcgcatccct
    24181 gctactgtcc ttattgtcgg tgtggccctt cttctcactg gttacactag tgccagactt
    24241 ggaaaggatc cgactagaac agctatgatt cggaaccttg ctattggtct cttgaccatg
    24301 ggagttacct tcctgctcga acaacttttc agcatttaga atacaagaaa tacctcgatt
    24361 ttgaagtcga ggtatctttt ttacatttgc acaatcttgc gataacttct tgaagtaatc
    24421 atgaaaatca gcacataggc gatgaggaag atagcgcaga tagacaaggt cacaatcaac
    24481 atcatagtcg tatccagtac accaatcact tttaaaatca ggctaagcat atggtaggca
    24541 aaggcgagat gtatgaaggc aaagagcaaa ggaaggaaga aaacagttaa aacctgtttg
    24601 ttgatggttt gcttgatttg cttttggtcc aaaccgactt tctgcaagat aataaagcgt
    24661 tcacggtctt cgtagccttc agaaatttgt ttgtagtaga tgaccagaac agttccgacc
    24721 ataaagataa tggataggaa aataccgata aagaagacac caccaaagag ggcactcatc
    24781 tgagaactag catctgctag attgctacca taaacatagc taccttctgt gtctaattga
    24841 gcattaaatt gattgaggta gttttcatac tcctcagcga ccttgagttg ttcttcttcg
    24901 ctggcatcta cattcatacc accgtaaaac tgattataga tagccgaatc tgggaattga
    24961 tccaaaaagg cttgtaaatc aggaacaaca aggtaattgt aatcagtagt caagatatta
    25021 aacttatttg gaacatggtt gacaatgaaa tctttattaa attcttcttt gacagaaaat
    25081 tgatgatcat ttagagttag agctttctgt cctttcagtc cgtcattttt ggcaaagaga
    25141 ccgacctcat ttcctgatag agacagtttt tgaccagtca tattttcata atctttttgg
    25201 tcaaatacca tgaaaactgt ttttggttgg acacggtttt gtcctttttc aaaaatagtt
    25261 aacttggttc cttcttgatt tgcaatacca aagttactgt aacgaagcac ttctttctct
    25321 ttaatcttat aacctttgtc acttgcaaac tggctcaaga gtttgtccaa atcttctttt
    25381 tcaacatttt gccctgaaac cccaaaatca tgaggattta gaactttttt aaaggattct
    25441 gcggaattga aaatgcttgt cgctgctgac atggttacca aaaccattgt tgacaaaata
    25501 gcgatagttg ctagtccaac tgcatttttc ttcatacgga aaatcaagtt agaaacagat
    25561 atgagattat taggttggta atagtatttc ttatttttct ttaagatttg aaggaaaacg
    25621 gtaatccctg cattgaacaa aagataagta ccaaagataa ccagtaaaac agctatgaag
    25681 aaggttgtta aggctgtaag aggatctttt accgtaaggg caagataata tccaatccct
    25741 aaacttatgg aaccaagaat agtttggaga ggaaggaagc gacctttttt ctctccgcta
    25801 gctttctcac gtgagagctg gagggcattc atacgggcga ttcgaagggc attcaggaac
    25861 atgaggccta ggaaaatcaa accgaagaca agaagtactg taatgacaac tttcatctgg
    25921 aaggtagcga ccagttccac cttcaatttc atcagtttga gtaggaaagc gaaaatcaac
    25981 ttgtcaaaca aggctccaat accgattcct gctccaacag ttagaatccc aaatagcact
    26041 aactccttaa aggtcatact gattagatgg cgcttctcca agcctaacat gccatatata
    26101 cccagttcct tggaacggtt tttcatgaca aaactattgg catagaggac gataatggct
    26161 gacgcaaggg taacgacaaa cataccaaat ccaagtgttg cttgaatggt ggttcctcca
    26221 cggatttccg caatcttggg attgaaggtt agggagtaaa agagataggt gatggtgact
    26281 gccaagagaa cagccagtgc aaagggatag tagagtttgc ggtttttaat caagttcgat
    26341 accgctaact tattggttaa tcgaaacata ctaattcacc tcgcttgcca tgacagtcaa
    26401 ggtatcagag atttcttgga acaactgacg ctctgtcttc tctccacggt agatttggtt
    26461 gtaaagaatg ccgtctttga taaagagaac acgcttggcc ctgctagcag ctgctgttga
    26521 gtgggttacc atgaggatgg tttgcccacg ctcattgatt tcattaaaga catcaagtaa
    26581 ggttgcagat gacttggaat caagggctcc tgttggctcg tccgcaagga gaatttcagg
    26641 ttctgtgatg atggcgcggg ctactgctac acgctgtttc tggccaccag aaatctcgta
    26701 agggtacttc tcttgcaatt ggttaatacc cagattctca gctgtcacca ccaatttctt
    26761 catcatctcc gttataggtc ttcttgacaa gacaagcgga agcaagatat tgtccttaac
    26821 agacagagta tctagcaagt taaagtcttg gaagacaaat cctagctttt cacgccggaa
    26881 actagaagcc tgtgaatttt taatagttgc ggtgtcagtt ccattcaagt aaacctgccc
    26941 acgacttggt ttatccaaca tagctagaat attgagaaga gttgatttac cagaaccaga
    27001 ctcacccatg atggcaacgt agtcaccctt ttctacggta aagtgaatat ccttgagggc
    27061 ttctacttgg ttgccctgaa aacgtgtttt ataaattttt tgaacgtgtt ttacatctaa
    27121 aagtgtcatg agaatctcct ttcttaatat cccatcaaat gaaatgtagc ttgcatcata
    27181 gtgcatccca gctgaacgcg ctcaatttct ttgtgacttg gttttctagt tttcttatgt
    27241 aagatttgtt tcatgatgtt actcctttgt tctttatgag tctagtttac atcaaaaaaa
    27301 gaccgcttgc cataacctaa ccttacaaaa gagactttaa tcttacattt ttgtaagatt
    27361 gggtgaaata taagcaaaat tacttagaaa atgatttgat ttcctatttt taaagttgta
    27421 aaatataagt gtgaaaaggc ttactttgaa aaggaggaag cgggaactaa cattttagta
    27481 agcttaccta gataacatac cattcaattt aacacttgca agtcgttcaa cctataagga
    27541 aagaaggtgc gctttaatga aacacaaaga acatatactc atcggacttc tctatctgct
    27601 ctctccattc atcggtcagc tcttagttga acacacacac tttatcagta cagaatttac
    27661 cggcactgct tatgttattt gctggttatc agttgttatc agcatccacc atttttccaa
    27721 aaatgtattg tctcaacagc aaaaatagat taaaaaactg cgtttaaatt actgctttta
    27781 tagtaaaatg aaataagaac aggacaaatc gatcaggaca gtcaaatcga tttctaacaa
    27841 ttttttagaa gtataggtgt cctattctag ttccaatcca ctatagtttg tggatgaagc
    27901 tggcgaaata ttattaatac tattcaaaaa tcaaagtgca aactatatca acttcacatt
    27961 gccgactaaa ttacagcctg cggctggctt cctagtttgc actttgattt ttattgagta
    28021 taaaagtaaa aaagctttaa atcaagcagt ttagactatt gatttaaagc tttttgcgta
    28081 ttccaaatct tttgtaaaac ctcaccaaaa ccagccttca ttatcgtcaa tggcttgagc
    28141 ttctttgcgt ttacgtgggc ctgttccgta catttctgct tcgatttctt ccttggttgg
    28201 catgatagaa gctaggatga tatagataat caccccaagt ccaaagtttg cgactgtaaa
    28261 aatggcaaac agaaaacgta caagggtaac atcaaagttc cacttgtctg acagacctgc
    28321 taaaactcct gaaatcatgc gatttcgtct cattttataa aacttactgt tcatgatatt
    28381 tcctctttct gctaggttag actagtatat cacggatagg ctcggctttc atcagtcctc
    28441 aggctgattt actaatagca actttcctcg acaaagtcca cagcgatagc gttgggtatc
    28501 aatcctacgc ttacgctgat aagtttgctg gcaggattgg caacgataga gcttgattgg
    28561 cttggagtta ctattgggca aggatggtac aaaccgtaat ccatccactg ctttcaacag
    28621 ttccttaaaa tcccgatcct tgtgttgata gactttccct tgaaaataga ggtgataatg
    28681 acagagttca tgtcggacaa ttttcctaaa aacgtccaac cccagttcct gataaacctt
    28741 gggattaaaa tccaaatgcc catctttggg gaaaaatcgc ccacctgtcg aacgtagacg
    28801 cctattccac tggacatgat ggataaaagg tctgccgaag tcttctagtg aaacctgctt
    28861 gacgtaatca gtcagtttca tttggagcta ggagagacag attaactttt tcacgttcag
    28921 tatcaatttt cttaacccaa acgctcacca aatctccaac tgccaccact tgactagggt
    28981 gtttgataaa cttgcgactc atatgggaaa tatggatgag accgtcctca tgaattccga
    29041 tatcaacaaa agcaccgaaa tcaacaacat tacgcaccac tccttctagc ttttgtccaa
    29101 ccactaagtc cttgatatct aggacatctt gacggagaac tggagcatca aaggaatcac
    29161 ggaaatctcg acctggtttg agaagatctg caatgatatc tttaagagtt tctggaccaa
    29221 ggtctaactc ttgcgccatt tccttgactg aaagcgactt gagtttactt tgggcctctt
    29281 cattcagatc cttaatgtcc aagcatttga agagttcctt aacggcagcg taattttctg
    29341 ggtgaactcc tgtattatca aggatattgc tactttcagg gatacggagg aaaccagcag
    29401 cctgttcaaa agccttggcc cccaaacgag gaactttctt gatttgggag cgtgaagtga
    29461 tttttccctc ttcctcacgg tatttgacga tattttcaga aatggtttta ttgagtccag
    29521 ctacgtgtga aagaagagct gggctagctg tattgacatt gacaccaact tggttaacca
    29581 ctgtatcgac aacaaagtcc agactctcag atagtttctt ctgactgaca tcgtgttggt
    29641 attgaccgac accaattgac ttaggatcga ttttgaccaa ttccgcaaga ggatcttgca
    29701 aacgacgggc gatagaaatg gcagagcgtt tttcaacggt caagtctgga aactcctgac
    29761 gagcaagttc gctggcagaa tagacagaag caccactttc attaacgata acatagctga
    29821 cttcagggaa atctttcaga acttccgcta caaaagcttc actttcacga ctggccgttc
    29881 catttccaat ggcaataatc tctacaccgt attgaccaat taaatctgct aaatctttct
    29941 tggcttcttc gatttgacga gctgatgctg gtttaacagg ataaataacc tgagttgtca
    30001 gcatttttcc tgttgcatcc acgacagcta gcttggcacc tgtacgaaag gctgggtcaa
    30061 acccaagaac cacgcgccct ttcagtggag caaccaagag gagattgcgc agattgtcag
    30121 aaaaaagttg gatagctccc tcttcagctt tctcagttaa ttctgtccga atacgacgct
    30181 caatagcagg caagaccttt ttcttaacgg attgctgaac aacttcatca atataagcat
    30241 ttttcacctt gaaacgagta gcaaagaagg caagaatacg gtccgtcgca tgttcaaaac
    30301 cgatcttcaa gacaccaagt ttctccccac gattgagagc caaggtacga tagccttgca
    30361 tagttccaac tgtctctgaa aaatcataat aaatctgaaa aacctgcttt tcatcaagac
    30421 tttcatcctt ggcttgagaa gtgagtttag agtgtctcag cacttcctga taagtcatag
    30481 aacgcaaggt cacatcttcc gataaggctt cgaccaaaat atcaactgca ccggtcaagg
    30541 cttccttgcc agtcgcaaat ccttcacaga cgaacttttc agcttctttc tctaagtcaa
    30601 ctatattctg caaaatcaag cgagcaagag gaaagagtcc agcttcacgg gcaatggttg
    30661 ccttggtacg acgcttttcc ttataaggaa gatagagttc ttcaacgtct gctaattttt
    30721 cggcaactaa gatagcttct tccaattcct tggtcaactt accttgttct tgaatcttag
    30781 ctaagacagc ttccttacgg tcattgagat ttgtcagact tttatccaaa tcaataatag
    30841 ccttaatcgc cacctcatcc agactaccag tcatgtcctt gcgataacgc gcgataaagg
    30901 gaatagtcgc cccttcagct gtcaaactta gaacggtatc aatttgcttt aacgtcactc
    30961 ccaaatcctg agagattttt tcatattttt tatccataaa tctattatac cacaagctgg
    31021 aaggctttct ccaatccttt tcatactcaa taaaaatcaa aaagcaaact aggaagctag
    31081 ccgtaggctg ctcaaaa
//
LOCUS       DBERPV010000024        27284 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.24, whole genome shotgun sequence.
ACCESSION   DBERPV010000024 DBERPV010000000
VERSION     DBERPV010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 27284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27284
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.24"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..214
                     /locus_tag="ACL8C7_001370"
     CDS             <1..214
                     /locus_tag="ACL8C7_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000530076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS1395554.1"
                     /translation="VFKTFLKNKEKIVNALQLHYSNAKLEATNNLIKLIKRNAFGFRN
                     FENFKKRIFIALNIKKERTKFVLSQA"
     gene            complement(288..1484)
                     /gene="pgk"
                     /locus_tag="ACL8C7_001371"
     CDS             complement(288..1484)
                     /gene="pgk"
                     /locus_tag="ACL8C7_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HGS1395555.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            complement(1574..6484)
                     /locus_tag="ACL8C7_001372"
     CDS             complement(1574..6484)
                     /locus_tag="ACL8C7_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HGS1395556.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEAASAAKPEEKAGEVVAETPS
                     AEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKTLKPKEIKFNS
                     WEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSNTNSKAKDHAS
                     VGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLFFNWSNSIADQ
                     ERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLGEKMRQFMLYS
                     KEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPADNFFANFNWD
                     KAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGKLRLSLGLFAP
                     DTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADRTPAVGNTFTT
                     SFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAEYDFTDAYNGG
                     NSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAFSTTPDYKFDD
                     ADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNLGQLTISDNHQ
                     EPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKLLTGSSSTTIY
                     LPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLPKPLAENIVPG
                     ATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKSRTVVRWVMDH
                     AGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLDKPITAQDWRL
                     NVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQVGFADVPAGA
                     TITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGKEISNVLAVSV
                     PKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIRLTHAGVSVSG
                     FDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEPKKDYLVGDSL
                     DLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGHEVNFDVLVSP
                     KAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLKDHETSTQDQV
                     NDRLNKLTEAHKALNGQEKFTEEKTELDRLTGEAQELLAAKPNHPSGSALAPLLEKNK
                     ALVEKVDLSPEELATAKQSLKDLVALLKEDKSAVFSDSKTGVEVHFSNKEKTVIKGLK
                     VERVQASAEEKKYFAGEEAHVFEIEGLDEKGQDVDPSYASIVKIPIEKDKKVKKVFFL
                     PEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNTVLPKPTYQPA
                     SDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVFEVDENGQRRL
                     RSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQLPNTGTADANE
                     ALIAGLASLGLASLALTLRRKREDKD"
     gene            6777..8408
                     /locus_tag="ACL8C7_001373"
     CDS             6777..8408
                     /locus_tag="ACL8C7_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005436 - sodium:phosphate symporter
                     activity [Evidence IEA];
                     GO_process: GO:0044341 - sodium-dependent phosphate
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HGS1395557.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            complement(8967..10574)
                     /locus_tag="ACL8C7_001374"
     CDS             complement(8967..10574)
                     /locus_tag="ACL8C7_001374"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HGS1395558.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAAAMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDAEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(10964..11551)
                     /gene="rpoE"
                     /locus_tag="ACL8C7_001375"
     CDS             complement(10964..11551)
                     /gene="rpoE"
                     /locus_tag="ACL8C7_001375"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HGS1395559.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(11679..11990)
                     /locus_tag="ACL8C7_001376"
                     /pseudo
     CDS             complement(11679..11990)
                     /locus_tag="ACL8C7_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
     gene            complement(11888..12304)
                     /locus_tag="ACL8C7_001377"
     CDS             complement(11888..12304)
                     /locus_tag="ACL8C7_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395560.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLKNHI
                     LPLWIGMVSFFGLKSRRRENGFQLGILHYLRIISPL"
     gene            complement(12332..12982)
                     /locus_tag="ACL8C7_001378"
     CDS             complement(12332..12982)
                     /locus_tag="ACL8C7_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGS1395561.1"
                     /translation="MKDKQTFLMKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIR
                     GDLPDYLTILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIV
                     TFKNIYQRPRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIVQI
                     VLGLYLVSVLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(12972..13535)
                     /locus_tag="ACL8C7_001379"
     CDS             complement(12972..13535)
                     /locus_tag="ACL8C7_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGS1395562.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(13700..13934)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(13988..14491)
                     /locus_tag="ACL8C7_001380"
     CDS             complement(13988..14491)
                     /locus_tag="ACL8C7_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HGS1395563.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFMSQMKGKLYLISKFAEKIYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(14684..15514)
                     /locus_tag="ACL8C7_001381"
     CDS             complement(14684..15514)
                     /locus_tag="ACL8C7_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGS1395564.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(15499..17181)
                     /locus_tag="ACL8C7_001382"
     CDS             complement(15499..17181)
                     /locus_tag="ACL8C7_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1395565.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQAAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNMSIS
                     KGQVQLQNELAKETPELQSLFKLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DIVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            complement(17283..17540)
                     /locus_tag="ACL8C7_001383"
     CDS             complement(17283..17540)
                     /locus_tag="ACL8C7_001383"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395566.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEVVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            complement(17547..18095)
                     /locus_tag="ACL8C7_001384"
     CDS             complement(17547..18095)
                     /locus_tag="ACL8C7_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HGS1395567.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVINS
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(18110..18958)
                     /locus_tag="ACL8C7_001385"
     CDS             complement(18110..18958)
                     /locus_tag="ACL8C7_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HGS1395568.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            19147..20496
                     /gene="trkA"
                     /locus_tag="ACL8C7_001386"
     CDS             19147..20496
                     /gene="trkA"
                     /locus_tag="ACL8C7_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HGS1395569.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIEREHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            20500..21939
                     /locus_tag="ACL8C7_001387"
     CDS             20500..21939
                     /locus_tag="ACL8C7_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGS1395570.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDISVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYIALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRVKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNQTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(22064..22465)
                     /locus_tag="ACL8C7_001388"
                     /pseudo
     CDS             complement(22064..22465)
                     /locus_tag="ACL8C7_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS alpha-glucoside transporter subunit IIB"
     gene            23515..23799
                     /locus_tag="ACL8C7_001389"
     CDS             23515..23799
                     /locus_tag="ACL8C7_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395571.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            23792..24040
                     /locus_tag="ACL8C7_001390"
     CDS             23792..24040
                     /locus_tag="ACL8C7_001390"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395572.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVDGYVLEYHGLRATQDVD
                     AFYDQNQKINEIIARVGKQFNLNIHEELWLNNHVAKQI"
     gene            24136..24354
                     /locus_tag="ACL8C7_001391"
     CDS             24136..24354
                     /locus_tag="ACL8C7_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395573.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMEFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(24722..27046)
                     /gene="pflB"
                     /locus_tag="ACL8C7_001392"
     CDS             complement(24722..27046)
                     /gene="pflB"
                     /locus_tag="ACL8C7_001392"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HGS1395574.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
BASE COUNT         7938 a         5921 c         5043 g         8382 t
ORIGIN      
        1 tgtctttaaa acctttctaa agaacaaaga gaaaatcgtc aacgcccttc aactacacta
       61 ttctaatgcc aaactggaag cgaccaataa tctcatcaaa cttatcaagc gcaatgcctt
      121 tggttttcgg aactttgaaa acttcaaaaa acggattttt atcgccctga atatcaaaaa
      181 agaaaggacg aaatttgtcc tttctcaagc ttagcttttt ttcaacccac tacagttgac
      241 aaagagccaa ctttcatccc tctcttcttt gatttgttta taaaatctta tttttctgtc
      301 aaggctgcaa gtcctggaag aaccttacct tcaagaagtt ccattgatgc tccaccaccc
      361 gtactaatcc atgagaactt gtctgcacgg ccaaggttaa tcgctgcggc agctgagtca
      421 ccaccaccga tgattgattt aactcctggt tgtttcacga tagcgtccat cacaccgatt
      481 gtaccagctt ggaaatctgg gttttcaaat acacccatag gtccgttcca tacaactgtt
      541 ttggcaccag tcaaagcttc gtcaaatttg gcgatagatt ttggaccgat gtcaagacca
      601 aggaagcctt cagaaactgc ttcaccttca gtgtcacgca cttcagtgta accagcaaat
      661 gcgttagctt cttttgagtc aactggcaag atcaatttac catttgcttt ttcaagaaga
      721 gctttcgcaa catccaattt gtcttcttct acaagtgagt taccgatttc gataccttgt
      781 gctttgtaga atgtgtaagt catcccacca ccgataagga ctttatcagc tttttcaagc
      841 aagttttcga taacaccgat cttgtctgaa acttttgaac caccaaggat agccacgaat
      901 ggacgttctg gagtttcaac tgcttcttgg atgtaggcaa tttcgttttc aagaaggaaa
      961 ccagcaactg ctttttcaac gtttgctgag ataccaacgt tagatgcgtg tgcacggtga
     1021 gctgtaccga atgcatcgtt tacgaagata ccatctccaa gtgatgccca gtatttacca
     1081 agttcaggat cgtttttaga ttctttcttg ccgtcaacat cttcgtaacg agtgttttca
     1141 accaagagaa cttgtccatc ttcaagagcg ttgattgccg cttccaattc agcaccacga
     1201 gtgacacctg ggaaaacaac atcttgacca agttttgctg ccaagtcagc tgctacagga
     1261 gcaagtgatt taccagcttt atcagcttct tctttcacac gtccaaggtg agagaaaaga
     1321 attgcacgtc caccttgttc gatgatgtac ttaatagttg gaagagctgc tgtgatacgg
     1381 ttatcgttag tgattacgcc atctttcaat ggtacgttga agtcaacacg aacgaggact
     1441 tttttacctt tcaagtcaac gtctttaaca gtaagttttg ccatgttaca aaaactcctt
     1501 tatttatttt attcgaaact attatatcac actttggaaa tataaggaaa gatttcacaa
     1561 gatttttcga tatttaatct ttatcttctc ttttccgtct caaggtcaag gctaaactag
     1621 caagaccaag gctggctaag cctgctatta gggcttcatt agcatcagct gttcctgtat
     1681 ttggcaattg tttgcttgct tcttctgatt taactgctgt attttgagct ggtttttcct
     1741 gtgtagctac tactgctggt actgttttta cttttgttcc aatttcaaca atttctggaa
     1801 tcgcttcttg gatgacttct gttgaacgaa gacgacgctg accgttttca tcaacttcaa
     1861 agacatgtct taacagtcca tctcgtccct gtatgatgac tcgttgttcc ccaactagca
     1921 tctcagcatt ttcatgctct tgacgatgaa aggcaacctt ttcctcttga acttccaatt
     1981 taggagcctt ttgttgatca gaagccggtt gataagtagg ttttggaagg actgtgtttt
     2041 gtggtgctgg tttagcaggt tgtggttttt cagcagattc ataaacaaag gcataatgag
     2101 taaagtgagg tgctgtaaag ataacatgac tatccgtttg ttcaaaagcc aattctactg
     2161 cctctttgcc ttcaggtaag aaaaatactt tcttaacttt cttatctttt tcaattggga
     2221 ttttcacaat agaagcataa gagggatcaa catcttgacc tttttcatcc aaaccttcta
     2281 tttcaaagac atgagcctct tctccagcaa agtatttctt ctcttcagca cttgcttgaa
     2341 cacgctctac tttcaaaccc ttgatgacag tcttctcttt atttgagaag tgtacttcaa
     2401 cacctgtttt actatcagaa aagactgctg acttgtcttc tttcaataaa gcaaccagat
     2461 cttttagact ctgtttcgct gttgcaagct cttctggact caaatctact ttttcaacca
     2521 aggccttgtt tttctcaaga agcggagcta gggcagaacc tgaaggatgg tttggtttgg
     2581 cagccaagag ttcttgagcc tcacctgtta agcgatcaag ctctgtcttt tcttccgtaa
     2641 atttctcttg accattcaga gctttatgag cttctgtcaa tttattaagt cggtcattga
     2701 cttgatcttg ggtgctagtt tcatggtctt tcaacacttg ttcggccgct tcaattgctt
     2761 tcaagaaggc ttcttttact tctggtgaag caaagttata gaccaccttg ttcttagcag
     2821 cttcaacttc tgctaatttt tgtttgaggt actcatcgtt caatgctgct tttggagata
     2881 ccaaaacatc aaagttgact tcatgacctt ggtaacgaag cgtcaaggtt tgacgaccag
     2941 tcttttgagc atcgtaacca gaaatttcaa ctccctcatc agtaaaggaa tgttcttcca
     3001 tggtgtcatt gctataagcc actgcaaagc gtccttcaga caagtctaag ctatcaccaa
     3061 ctaggtaatc ttttttcggt tcctgactta cttcaattcc caaaatagtt ttcggacttg
     3121 cttcatcttg gccagtgaca gtcactgaca aattagcatt tactggttgt cccaaatatt
     3181 ggagagtaag attctgttct cccttatgat gcgtatcaaa acctgatact gatacacctg
     3241 cgtgagttag gcgaatgagt tcgtcctcag ttcctccttc atactgaact cgaagaacac
     3301 cacctctaag gtccaaatcc tccccttcgg cgtagcttgt tttcttaggt cctgtttcta
     3361 ggctgactga cttgattctt ctgtcatctt ttggaacgga aactgctagg acattactaa
     3421 tttccttgcc tggcaactgg gtacgataat aaagaagacc agattgattt gtcaaatcca
     3481 atggtgcact tgctaggtct cctccaactt cgctcttcaa ggttgcgagc ggagtttgag
     3541 aatttggatt atcataaacg gtaatagttg ctccagccgg tacatctgca aagccaactt
     3601 gtaccttgtt attgcctaga gaacgggctg cagccttggc catcggaata ttgacactct
     3661 cagtatcaag cttttcatac attttccagt tatagatacg aatagccttc catggagttc
     3721 cattgtcaga agtgacaaca ttcaagcgcc agtcctgagc agtgattggt ttatcaagag
     3781 tgatatctgt cacgtgtgct ttgttaccac ggacttcctt agctagcttc cactcaccat
     3841 ctgcatcttt ataataaagg tcaaagtctt tagtgttcat caagccatcg ttaacagact
     3901 caccaccagc tcctgcatga tccatgaccc atctaacaac ggtacgtgac ttggtcaaac
     3961 gaatatccac actaccactc aactgagctg aagaccattt atctgacaag ctagtaatgg
     4021 taccgttcaa cataccttca ataccttctc caccttcagt cttagggaaa gtactatcaa
     4081 taactgttgc acctggaacg atattttcag ctagtggttt tggtaggctg gtatctttta
     4141 cagtcatacc ccaatcaaag gttgtggttg cagcttctga acgaactcca tttttaccga
     4201 ctgctacaac cttcagttct tgagttgtac cctgagcact tgctgagcgg ctaacttttg
     4261 gtagataaat agttgtagaa gatgagccag ttagtaattt ccagctgtct ccatcttttt
     4321 cataaacttc atagaaatct gcatccttgt tgcctttaaa ttgcacaact gcttccgctt
     4381 cttgggcatt tttaagagat tgtttcacta cagaaaagct tgtcggcgat tgtggctctt
     4441 ggtgattgtc cgagatagtt aattgtccta ggttgaactg ataatctttt acagcacctt
     4501 catgctcgaa aaatagtttg actgcataga tggttttacc tgctagtgag ctgagatcaa
     4561 attcttcatt tgtccagttg tcagaaaggg ttagctcttt ccatgcatct gcatcatcga
     4621 atttgtagtc tggagttgta gagaatgcca tataaacttt agaacctttt cctcccttgt
     4681 gggcaacacg aagtttggtc ttctcagtta cttctaactt agtagaataa agtctcacat
     4741 cctgatctgt cttaccggct acatcaccag agaatttaag ggaatttccg ccattatagg
     4801 catctgtaaa atcatattct gcacgaagtt tttcccctgt tgaagtctgc caccagcgcc
     4861 atgttggaag aacacctgat actgaacgat aattccactc agaatcctta gaaaccttac
     4921 catctacgaa ccatttttta ccatgacctg tattaaaaga agtagtaaaa gtattaccta
     4981 ccgctggcgt acggtccgca actaggttag caataccata ccaatctttg tcacctggtt
     5041 tttggccagt agggtctcct tgataacctg taaagaagat atcttcattt ttatgataat
     5101 cttcaccagt ttttcctaaa cttgtaatgg tatctggggc aaataaacca agagaaaggc
     5161 gcaatttccc attttcgtct aaaatgtcat tccacttaac ctttgtcttg taggaaccac
     5221 cctgttgcaa ttccaaacct gcaaatacat cataaggatt acgaccaatc cagttggcag
     5281 ttgcaatagt gtaatcattt ttagccttat cccagttaaa gttagcaaag aagttatctg
     5341 ccggaacctt atctccttct ggttgcatga attggtagtt gtattctccc aaaccatctt
     5401 gatggtaacg tccatagtta taggtcatgg catcatacca agaatacttg attggatggt
     5461 ttaccttagc agcatattcc ttgctataga gcataaactg gcgcatcttt tctccaagag
     5521 gtttaaccaa atctccagtt gtttcttggt tgatgaaata gccatcatag ccataatact
     5581 tggccatgtc taccaattta cgggcaattg ggaagctacc atctgcgtct tgcttcaaag
     5641 cttcagcaaa tctttcttga tctgcaatac tattagacca gttgaagaag agtgtaccgt
     5701 atacaggaac cccgttacgg tgacctgcat caataacgtc aggagttggt acgagacctt
     5761 cccagaagac cattgaatct agatattgcc aatagtcaaa agcataggcc ttgaactctt
     5821 ctccaccaac agaagcatgg tcttttgctt tagaattggt gtttgataag gcttgaactt
     5881 ttgcttcctt gctagctttt tcattgacta aatgacctgt ccgacgtgaa gcgaggacaa
     5941 cagatccgcg gttaatagca tcatcttcac gagcacctgg ttcccatttt aacaattctt
     6001 cccaagaatt aaatttgatt tcctttggtt ttaatgtttt ttctgtattt ttagggacat
     6061 ctggctggac ttctttttca gtcttattag cttctgctgc tggcttagac tcatcccctt
     6121 ggttagttgc ttcgggcttt gcttctgttt ccttgtcaga cttaggtttt gcttctgcag
     6181 atggtgtttc tgcaaccacc tcacctgctt tttcctctgg tttagctgcg ctagctgctt
     6241 ctgccttttc tagcttgttt tctctagcat gttccccttc attctgctta tcagcttcat
     6301 tggtcgaatg ctcactctct cctgaaacaa gctctgtatt agctccgcta ttttcaggaa
     6361 ctgcagtttc ttcagccaag gctggaccag caaataaaac agcaccaatc atcagcgagc
     6421 aggctcctac tgataactta cgaatactgt aacgacaacg tctttcaaaa aatggattct
     6481 tcattttctc ctcctaaaag attgattttg ttgttttaaa gaaagcgctt tatattctgt
     6541 agttttttat caaactctag aaccatgata atcacatttt tatcctaaaa catttttaga
     6601 caaaaaacaa taactgtttg cacaaatcta aaataaggtt aaaaactctt aaaaataata
     6661 cacttatcaa ttataatttt cttttacaaa cttgacatta acacttgtta gatttacttt
     6721 tatcctttaa aatagaatag gagatattcc gcgattattt ttcggaggaa aaagaaatgt
     6781 ccattaattg gcaggaaatt ttatttcact ttttaggtgg tctggggcta ttcttatata
     6841 gcatcaagac catgggagac ggtttgcaac aagctgctgg agatcgcctt cgtttttaca
     6901 ttgacaaata tactagtaat cctttctttg gagttctggt tggtattggg atgactgctc
     6961 taattcagtc tagttctggt gtaacagtta ttacagtcgg cctggtcagt gccggtctct
     7021 taaccttacg tcaggctatc gggattgtca tgggtgctaa tattgggaca actgtcacat
     7081 cctttctcat cggttttaaa ttaggtaact atgccctacc tatgctcttt atcggtgccg
     7141 tctgtctctt ttttacgaaa aatcggacag tcaataatat cggacgcatc ctctttggtg
     7201 tcggtggtat cttttttgcc ctcaatctca tgagcggcgc aatggctcca ctcaaggatt
     7261 tacaggtctt taaggactat atgattgagc taagtaagaa tcctgttttg ggtgtctttg
     7321 tcggtaccgg cttgaccttg ctaattcaag cttcttcggc taccattggg attttacaaa
     7381 acctctacgc cggcaatcta attgacctac agggagcttt gccagttcta tttggtgaca
     7441 atatcgggac aaccattaca gccatcattg cctctttagg ggctaatatt gcagctaaac
     7501 gggtagcagg agctcatgtt gccttcaacg ttatcggaac agtcgtctgc gttatttttc
     7561 tagttccttt tactgtcctg attcattggt ttgaagctac gctaaatcta gcaccggaaa
     7621 tgaccatcgc ctttgctcac ggaaccttta atattaccaa caccattgtc caatttccat
     7681 ttatcggagc tctggcttac tttgtaacca agattattcc tggagaggac gaggttgtca
     7741 aatacgaacc cttatatctt gatgaacatt tcatcaaaca agccccatct atcgctctag
     7801 gaaatgctaa aaaagagctc ttgcacttag gaaactacgc tgctaaagcc tttgaccttt
     7861 cctataagta catcattgac ttggatgaaa aagttgctga aaaagggcat aaaaccgaag
     7921 aagcaattaa caccatcgat gagcaattaa cacgttatct cattgccctt tcaagcgaag
     7981 ctctcagcca aaaagaaagt gaagtgctca ccaatatcct tgattcctcc cgtgatttgg
     8041 aacggattgg agaccacacg gaggctctac tcaatctgac tgactatctt caacggaaaa
     8101 atgttgaatt ttctgatgcc gccttgaaag aattagagga agtttaccgc caaactagtg
     8161 actttatcaa agatgctctg gatagtgtgg aaaacaatga tattgaaaaa gcacgcagtc
     8221 ttgtagaacg tcatgaagca atcaataaga tagaacgtgt tctcagaaaa acccacatca
     8281 aacgcctcaa caaaggcgaa tgttcaacac aagctggggt caactttatc gacatcatct
     8341 cacactacac tcgtgtatca gaccacgcta tgaaccttgc tgaaaaggtt tttgcagaac
     8401 aaatctaaga accaagaagc tatccatcat aattggatgg cttcttactt tttcctaagc
     8461 aagactaggc tgaatgaaac tgaaagagta ttctgcagat atatagtata ttgaaactag
     8521 aatagtacac ctctatttct aaaacattgt tagaaatcga tttgactgtt ctgatcgatt
     8581 tgtcctgtta ttatttcatt ttactatagt ggattaaatt aaaaaagtat aatgtattga
     8641 atctataaca gtacatcttg actgctaaaa tatttctata aattaatttg actttcctta
     8701 tagagatgtt cacatcttat ttcaattcat gatacaatcc agttcctaaa actttgctag
     8761 aaattaattt ggctttccga attaatttgt tcagatttta tttcatttca atatactgat
     8821 aaatccattc actagcacag ggcaagaggg agtcgctatt gatttcaacg gtagcaggta
     8881 catacagagg actcctacct cagatatact gcaatatcat cgtatgcaaa aaacctctga
     8941 gatttttctc aaaggttctg attttgctaa ttgctgttct caaccgctgc agtaacaaag
     9001 gcagtgtaga gttcttctgg tcggtttgga cggcttgaca gttcagggtg atactgacaa
     9061 gctacaaaga atttattttc aggaatttcc acgatttcta ccaaacgatt gtctggagaa
     9121 actcctgaaa agacaaaacc tgctgcctca aactgctcac ggaaggcatt attaaactca
     9181 taacggtgac ggtgacggcg ttgcaccact tcttgattgt gataagcagc agcagcctta
     9241 gagccacgtt tcaacttaga cggataaagt cccaaacgaa gggttccacc catatcctca
     9301 atatcaatct gatcacgcat gatatcaatg atagggtatt ttgtttctgg tgcaagctct
     9361 gcagaattgg caccttcaag acctaaaacg tgacgagcaa actcgataca tgtcaactgc
     9421 attcccaagc agactcccaa cattggaaca tcattttcac gcgcatagcg gatggcttgg
     9481 attttccctt ctgtaccacg ttgaccaaaa ccacctggta cgatgatccc gtccgcatca
     9541 gacaagagtt ctgctacatt ctctgctgtc acatcattgg cattgaccca attgatttta
     9601 acttctgcat cattgacata gccagagtgt ttcaaggctt cgaccactga gatataggca
     9661 tcttgcaact ccacatactt accaacaagg gaaatcttaa cttgtttctt gaggttcatg
     9721 accttgtcca ccatggctga ccattctgtc atagccgctg ctggtgcgtc taatttcaaa
     9781 tgatcacaaa caatttggtc catcccttgt gcctgcaagt tcagtggaat ttggtaaagg
     9841 tgttcaacat ccaacgattc gataacggct tctggtgcca catcacagaa ctgggccagt
     9901 ttatttttaa ttccttgacc agctggctct tctgtacgaa taaccaacat atttggttgg
     9961 attcccaagc cacgcaattc tttgacagag tgttgggttg gtttggtttt catttcacca
    10021 gcagccttga ggtaaggaag caaggttgta tggatataca tgacattatc cgcacccaca
    10081 tctgccttca tctgacgaag agcctctagg aatggcaagg actctatatc tcctactgtt
    10141 ccaccaacct ctgtgataat gacatcagag tcggtcgtta gagcggcacg cttgattttt
    10201 tctttcaaag catctgtgat atgaggaatg acttgaacag ttgccccaag gtattctcca
    10261 cggcgttctt tacgaagaac ttcactgtaa attttcccag ttgtcacgtt ggaatatttg
    10321 ttgagattga tatcgatgaa acgttcatag tgacccaagt ccaaatctgt ctcagctccg
    10381 tcatctgtca caaaaacttc cccgtgctgg taaggactca tggttcccgg atcaatattg
    10441 atataagggt caaacttttg aatggttact ttgagaccac gatttttcaa gagacggcct
    10501 agactcgctg ccacaatccc tttcccaata gacgatacca caccaccagt tacaaaaata
    10561 tatttcgtag acatagattc ctctttctaa aatgctcaag gtcttgttaa ctacgagggg
    10621 atatagaaaa caagacccta ctaataagaa taatctggga cgactgcacc agattcacaa
    10681 ctaatactct tcgaaaatct cttcaaaccg cgtcaacgtc gccttgccgt agatatgtgt
    10741 tcctgacttt gtcagtctta tctacaacct caaaacagtg ttttgagcag cctacggcta
    10801 gtttcctagc ttgctctttg attttcattg agtataaaat acaagaagat aacttcttga
    10861 aaaaacaaaa atagctccct aagaactagg gagccccgac ctctaaaaga ggtgcccaaa
    10921 caatatgata cctaaaaata ggataattgt caatagctaa ctcttattcc tcgctggttt
    10981 cagcgtcgtc atctgaaaac tcgtcgtcgt cttcgttgag atccacatct tctcccaagt
    11041 catctggagc gatttcgttg atttctgcat cataagcttc cacttcattt ttttcatcat
    11101 ctggattttc atcatcgtat gaaagagctg gatctgcttc gtatgcatct tcgtcttctg
    11161 gatcatctgc attgtagtca atggcatctg aatcaccatc cataaaggca ttgacacgtt
    11221 ttttcttagc ttttggtgct acttcatcgt cgtcattttc ttcaagagcg atgatttctt
    11281 cgtcgatttc gtccacacca taccatgaac gaagacccca tttgttgtcc ccaagtgaga
    11341 tgaagctacc gtcaaagttc aactctgtgt agaacaaagg caaagcttcg cggatatcgc
    11401 tgtttgatgt tccaaggtag ttttgaattt cgtttacaag atcgctaaaa tgcatctcat
    11461 gatcgcgacc acgaagttct aagatagcac gcgctacctc aatcatagat agttcacttt
    11521 tttcttgccc agcaaatact tctaattcca aagcgtttct cctcatttat actactatcg
    11581 tcagagcgaa cagactctga cctcatttta tcatttactc tttattttac gataattttg
    11641 cggaatagtc aaaggttaag ggggagaaag tggcaggatt agactaattc caatataaaa
    11701 ctccttcctt tttctgttgc tccattttcc acaaatccaa gcgacttgaa acacctccta
    11761 gaagcatgat tgtaggtgta gatttccttg actctcaatt ctttccatcc ttttactcga
    11821 gccaattcaa tcaaagcact tagaatcttt tttccaagtc ctcgatgttg gtaagcggaa
    11881 ttcccaatca caatggggag attatcctga gatagtgtaa tatccccaat tggaaaccat
    11941 tctcccttct ccttgacttc aatccaaaaa agctcaccat gccgatccaa agaggtaaga
    12001 tatgattttt taaatcaaaa acagagtaaa tctttctttc ctcgcaagct tgcgcataga
    12061 gatgatatag ttcatcacca ccatctctat cccactcagc agaaatcgta tcccgacctg
    12121 ccaataaagc ctgataagcc ctgtgatgcc catctgtaat cagcaaacaa tctccaaagg
    12181 caagaatact gattggatcg acttggattg tttctgccga ctggtaaagc atctgaatat
    12241 cttgcaactt cttttctgat aaatatagtt gagtcggatg aagatctgct atattgactt
    12301 tcatttcttt ctcctcaagg gaattcgata ctcacttctg tttgccttta aatcgccatt
    12361 ggaagcggag cttgtcatag aagggaaact cgataaacaa aactcccaag cccacacaga
    12421 gactggcaag gacgtctgat gggtaatgaa ctcccagata gactcttgat accagcacac
    12481 tgactaggta gaggccaagg acgatttgta cgatttttct ccagacctga tctttaatcc
    12541 gctgactaag aataacaatc aaagtcccta ccatcagcgt tacagctaga gaatgcccac
    12601 ttgggaagga aaatcccttc tcctccacca gatgtaaaat agctggtcgt gggcgctggt
    12661 agatattttt aaaggtcacg attaaaagac ctgccaaagc cagatttccc aacatgaaga
    12721 aactttctat cttccatcgc ttacgataaa agacaaaagc tgtaatgaca acccaagtga
    12781 taatcactgg gatatcaatc agacgtgtga gggctcgaaa aagaatagtc aaataatctg
    12841 gtaagtctcc tcgaatggca gtctgaatcg attggtcaaa attgaccaac atttcagggt
    12901 aaaatttgac catatagcca agaataacga aaagtaaaag ggcaaaactg cccttcatta
    12961 aaaatgtttg tttatctttc atagtgtttt aaggttggtt tcaaaaggac gtacaacaac
    13021 cagaatgaaa cggaaaagat tacaccctca atcaagttaa aaggtaatac catggtcatt
    13081 aggtagttgg aaagtcccaa aatttttcca atatcaaagt tagcaaactt agcgtacaaa
    13141 ggaacagcat aaacatagtt gagaaccaac atggccaagg ttaaaccaac agttccagct
    13201 agagagccta gtaggaaacg aagggttgtc cgttcctttt tccaaatcaa agcaaatacg
    13261 atgacaaaaa ctcccaaagc tacgatattc atcggcaaac caatgtaagt attcactcct
    13321 tggctgttaa gaagcaattt caatagtgag cgaagcaaga gcactcctag agcagcaggc
    13381 aaatccatga ccaccagacc cacaaggact ggcaagatac taaattcgat cttgaggaaa
    13441 gatgccgctg gtaaaagcgg aaagtcaaag tacatcagca caaatgagat ggctgataga
    13501 attgcaatgg tcgaaagtcg acgtgtgttt gtcataacag gttcctccaa ttttctataa
    13561 aatcagaaga agttggaaag gattcctcta tctattctca ctttttatat cccaaaagtt
    13621 ccctcttact ctattaaaga aaaacaaagc aagtggttac aatccggcta taaatctatc
    13681 aaaacagaca aagctattct ttcgtcttct cccatccaga ctatactgtc ggttgtggaa
    13741 tctcaccaca tcagcttgcg ctcgcggact tctttaaaga gaaggaaata gagatttttc
    13801 ttttagacta ggcgacaagc tgtaggcata acttctggtt aggcaaagct tgtcaacaaa
    13861 gtataaaagg aaaagatcat ttcctagtta aagtcaccgc cggtcgggaa tcacaccctg
    13921 ccctgaagac tcttttatca taacaaaaaa cgcttgcaag cgcaagcatt ttgttcattt
    13981 tcatttttta tttcaattta tccacttcat aggtatggac gagctcaaga cctgcaaagt
    14041 tctgctggcg aagagcctca tagacaatca tgcagacggt attagacaca ttgagactgc
    14101 ggacatgttc atcattcatg ggaatacgga gagccttctc aggatgttct cgcataaaat
    14161 cttcaggtaa gcccttgtct tcacgtccaa agagaaaata atggtcctcg tcagtcgata
    14221 aatccacctc agaatagatt ttttccgcga atttcgaaat cagatagagt tttcccttca
    14281 tctgagacat gaaatcttct aagctctcgt aaaaataaat ctctagctta tcccagtaat
    14341 ccaatccagc ccgcttcatc ttgcggtcat caataggaaa gcccataggc ttgatgatgt
    14401 ggaggggaga attggtcgca gcgcaagtac gcgcgatatt gcctgtattt tgtggaattt
    14461 gaggttcaaa taatacaatg tgatttgtca tgacttgctt cctttcacca ttgcaaaaaa
    14521 atagccacac tgcccggagt caagctcagc aaacagcgtg gttaaggcat cgttaactta
    14581 cctcacaaca ggtttgaagt aaatcagcga aactactttc ttagtataac actttcagaa
    14641 tcattgtcaa tagaaatgac ttgatttttt caattttttc aagctatttc caagggttgt
    14701 aaaatcgtcc ctgattctgc aagataagta gtaaactaac tactaaaaac aaggttgcca
    14761 agagcaaggt aatatagtct ccttttttca aggcctgata actataccat gtgcgttttt
    14821 tctctttccc aaagcggcga agctccatgg cagtcgcaat ggtatcaatg cgttctagcg
    14881 agctaaaaat caagggcgta ataatgagca gattgccttt gattcgttgc ataagagaag
    14941 ctttcttgga taattccatc ccacgcgcct cctgagacat cttgatagta aagaattctt
    15001 cctgcaaatc tggaatatag cgcaaggtca ggctgacaga ataagcaatc ttatagggca
    15061 caccaatttg atttaaactg gaagcaaact gactaggatg ggttgtcatc aaaaagataa
    15121 tagccagagg aatggtgcaa agatacttaa tggccaaatt tagcagataa aagagctcct
    15181 ggctggttag agtgtagaca ccgattccct gccaaatcac acttctctct ccataaagtc
    15241 caaccccata ctcgggagaa aagagataga ccatcaaaac gtttaaaacg gcaaataccg
    15301 tcgcaaaaac ggctacaaag gaaacatctt taaagcgaat ttctgataaa tagaggagaa
    15361 agactgaaaa gatggcaatc agcaagagca ttctggtatc atagctaatc atggccgcca
    15421 atgataccag aatgaaaaag agaagtttcc cagctcctga caagcgatga atcacagtat
    15481 ctctatgctg gtaaccgatt aatttagctt gcatccctct ctcctttctt tgtaaaatgc
    15541 cgttaaatcc agtggatcca catctagttt cttagccaag ttaaagatgg aggtttcttt
    15601 tagattggct tttactaaca gctcaggatc gctcaacaga ctggctggaa caatatcggc
    15661 aatcaattct ccatccacca tgacaaggac ccggtctgaa taatccagca tcaattgcat
    15721 atcatgggta atcatgacaa tggtatgccc tttttgatgt aactcttcga gaaattccat
    15781 aatctcagta tagttcttct gatcttgacc tgcagtcggt tcatctagga gaataatttc
    15841 agctcctaag accaaaattg aagcaatggt gacacgtttt ttctgaccaa atgacagggc
    15901 agaaataggc caattacgga attcataaag tccacagatt ttcaaggttt catagactct
    15961 cgtttcaatt tccttctcat ccacacctcg caaacggagc cctagagcca cctcatcaaa
    16021 aatcatattg gttgaaatca tttgattagg attttgtagc acatagccta ctcgttccgc
    16081 ccgctctgca acagaatcgc cttttatatc ctgtttttcc caaagatagc gtccttccgt
    16141 ctgaataaag ctacttatag ccttggctag agttgatttc cctgctccat tttttccgac
    16201 aatagcaatc ttttcaccct ttttaatatc taaatgtagg gattttaaaa tcggtctatc
    16261 atcataagag aaagacacgt cctctaattt aaagagtgac tgcaattctg gagtttcttt
    16321 tgccagttca ttctgcagct gaacctgacc ttttgagata gacatgttat ccagattcgc
    16381 taactgttct tccttgacta agtccacacc taattgacgg agagtcgtta gataaagggg
    16441 ttctcgaatt ccattttgag tcaataaatc agtcgcaagc aactggtcag ggctcccatt
    16501 aaaaaggata cgaccatcgt ttatcaagac aatccgatcc acagggcgat gcagaacgtc
    16561 ctccaaacgg tgctcgataa taagagtcgt cgtcccctct tccttatgaa tctggtcaat
    16621 caattcgata atatcctgac ctgacttggg atctagattg gcgagtggct catcaaacaa
    16681 gagaatcgga ctttcatcaa tcaagacacc agccagactg actcgctgct tttgtccacc
    16741 tgacaaatcc tgaggacgct gatccagtaa aggaagaagg tccagctttt cagcccattt
    16801 ataaacacga cctttcatct catctaaggc tgtcacatca ttttccagag caaacgccaa
    16861 atcttctgcc acagacaagc caataaactg cccatctgta tcctgcaaaa ctgtgctaac
    16921 cagatgagac ttatcataga tgctcatatc aaaggctgct tgacccttta tcaaaaattc
    16981 tccatatgtc tgacccttgt aaatattggg aataatccca ttcaaacact gacccaaggt
    17041 agatttacct gacccagatg gtccaacaat taagactttc tctcccttgt aaatggtcaa
    17101 gtctatccct tgcaaggtcg gttcttgttg tgtttcatac cggaaagaga aatccttcca
    17161 ctcaattata gcttctttca tcttactctc ttcattcgct tcttagactt ctattttatc
    17221 ataaatcaag cccttcttgc agtctcttct cttaaaatct tagcgccaaa aagattccta
    17281 tcctagctta cttgcctaac taatctataa acatcgaaaa agactagttg cccagccttc
    17341 cccatcattt tatactcttc gaaaatctct tcaaaccacg tcagcttcgc cttgccgtag
    17401 gtatggttac tgacttcgtc agtttcatct acaacctcaa aaccatgttt tgagctgact
    17461 tcgtcagttc tatccacaac ctcaaaacac tgttttgagc aacctgcggc taacttccta
    17521 gtctgctctt tgattttcat tgagtattag tcctttttca aacttcctgc acgagtttgg
    17581 gttcctgcat aggcaagtaa gagaagagtt cctgcaatag ctacagatac accattggca
    17641 attcccgcaa caatcccttg tgcaaatact ttttctgctg cttcttgata aatcacaaca
    17701 tctccaagtg gtgccaagac accccaaaca agggcatttg caagtagttg aatgagatta
    17761 aaaataagaa tatctttcca gtcaaaaaca ctattgatca cgcgaacgta ctttctaaaa
    17821 agtcccacaa ctaaaccaaa gagtccgcta gcgataatcc aagtccacca tagaccataa
    17881 ccagcaagag agtccttgat tgcatgacca attaacccga caagcaaacc gataatcggt
    17941 ccaaaaataa tagaaagtag cgcttgtacc gcatactgaa gctggatgct tgtatttgga
    18001 acaggggttg gaatgttgat catcccgatg acgacaaaga gggcagcgcc aattccgaca
    18061 gcaacaactt gtttaattgt aaatttgatt tccatactat tctcctattt tatccttcta
    18121 ttttctttat ttcaatagtc caagatgaac cgacacctac attataggcc ttggcaaagg
    18181 aaccttggtt gatagccaaa cctaaacgat agagagagtt gatgtaaaga atgggttgcc
    18241 caattctcac atctgcaaat gatttgccat agacaacctg attttgatag accagcatat
    18301 cagcatgata gatggtcact tcaaaacgat caccaaattc tggttccaac ttgtaaaatt
    18361 cttcccgtgt gatagaggtc caaagcgaac cgaaacgcac atccagaata tcaatggctc
    18421 ccttcaccag atgatcttct atgatggtcg ctacgactgg aagctctaca atctgttcca
    18481 cactgagctc tggccctact tcctcaaaag taatgtgacc actggccagt ttagcaccag
    18541 tataggcata gacatcacga ccgtggaagg tataagaatg ctctgtgttt tgacgcctat
    18601 tggccacctc agaaatctca cgaatggcta caatgccaac gtgtttcttg ataaaggaaa
    18661 gcgtcccatt atctggcgtg acaatgtatt gattttttgc agtcttggca actacactct
    18721 tacgtttcga accgacacct ggatcgacaa ccgatacaaa cgtcgttccc tcaggccagt
    18781 aatccaccgt ctgaaagaga cgatagctcc cctcaaaaat attataaggc gtgatatcgt
    18841 gcgtcaagtg atggattttt aaggttggag actcttctaa agccactcca atcatagccg
    18901 ataccgcacc atcaaccaga ccaaagtctg attgtaatac cagtaaatta ttattcattt
    18961 tatctccttg tatatccttt atcataccat atttcagaga aagtcgctaa tagctatttc
    19021 aattggttag ggtatagttt taacttatag caaatttcct actaaaaact ctggttatta
    19081 gctagtaggt gcattttttc ttgaaaaagg gtatgatagt tacatcatga aaaagtaggt
    19141 tttattatga aaattatcct tgtcggaggg ggaaaagttg gttttgccct ctgtcgctcc
    19201 ttggttgcag aaaagcatga tgttttgctg attgagcaag acgaagctgt tctcaatcat
    19261 attgtcagtc gctttgatat cattggtatc cttggtaacg gggccgattt tgccattctt
    19321 gagcaagcca gcgtccaaga ttgtgatatc tttatcgccc tgactgagca cgatgaagtc
    19381 aacatgattg cagcagttct agccaagaaa atgggagcta aagaaactat cgttcgggtg
    19441 cggaaccctg aatattctaa ctcttatttc aaggaaaaga atattctcgg tttttctctt
    19501 atcgttaatc ctgagctctt ggctgcccgc gctatcgcga atatcattga cttccccaac
    19561 gccctgtctg tcgaacgctt tgctggtgga cgcgttagcc tcatggaatt tgtcgtcaag
    19621 tccaccagcg gtctttgcca aatgcccatt tctgattttc gtaaaaaatt tggtaatgtc
    19681 attgtctgtg cgatagagag ggagcatcaa attatcattc caagcggtga catgactgta
    19741 caggataaag atagaatctt tgtcactggt aaccgtgtcg atatgatact cttccataat
    19801 tattttaaat cacgcgccgt gaagagcctt ctcatcgttg gggcaggtag aattgcctat
    19861 tatctacttg gtattctcaa agatagtcgt atcgatacaa aagtcattga aatcaatcct
    19921 gaaatcgcca gcttctttag cgagaaattc ccaaatctct acatcgttca aggagatgga
    19981 accgcaaaag atatcctgct ggaagaaagt gctcaacact atgatgccgt tgcgactcta
    20041 acaggtgtcg atgaggaaaa tctgattaca tctatgttcc ttgacagggt aggtgtacag
    20101 aaaaatatta ctaaggtcaa tcgtaccagt ctcctcgaga ttatcaatgc gcctgatttt
    20161 tcaagtatca tcacacctaa aagcatcgct gtagatacga ttatgcactt tattcgtggt
    20221 cgagttaatg cccagtattc agaccttcaa gccatgcacc atctagccaa tggccaaatc
    20281 gaaaccctgc aattccatat caaggaagcc aataaaatga ctgccaaacc tctttctcaa
    20341 ctgaaattga aaaaaggggt tcttattgca gccattattc gaaagggcaa gactattttc
    20401 ccaactgggg aggatatgtt ggaagttgga gacaagctcc tagtaacaac cttgttgcca
    20461 aacatcacca agatttatga cttgattgcg aggtaaaaaa tgaataaaag tatgattcgt
    20521 tacctccttt caaagttact tttgattgaa gctgttctcc tcttggttcc tgtggctatc
    20581 gctgtctatt accgtgaatc gagccaagtc tttacggccc tcttttcgac catagggatt
    20641 ctcgtattgt taggcggttc agggagttta cagaagccaa aaaatcaacg gatttatgcc
    20701 aaggagggag tcttgatcgt tgccctctgt tggatccttt ggtctttctt tggtggtctc
    20761 ccctttgtct tttctgggca aatccccagc cttattgatg ccttttttga aattagttct
    20821 gggtttacaa ctactggagc aagtattttg aacgacattt cggttctcag ccgttccctc
    20881 ctcttctggc gaagttttac ccacttgatt ggagggatgg gagtgcttgt ttttgcactt
    20941 gctattatgg acaatgccaa aaatagtcac ctagaagtaa tgaaggctga ggttcctggt
    21001 cctgtctttg gtaaggttgt atccaaatta aaaaacactg cccagatcct ctatctcctt
    21061 tacatagccc tcttttccct ctttgtcatc atctattatc tagccggtat gcctctctac
    21121 gatagttttg tcattgctat ggggacagcg ggaactggag gatttaccgt ctataacgat
    21181 ggaattgccc actatggtag ctcactgatt acctatctgg ttagtatagg agttttggtt
    21241 tttggggtaa atttcaatct ctactactac cttatgctcc gtcgggttaa ggccttcttt
    21301 ggtgacgaag aacttcgggc ttacttggtc attgtactgg tttctacagg cttgattagc
    21361 ctcaacaccc tctacctcta cccagggttt tcaaagagct ttgaaatgac cttcttccag
    21421 gtttccaaca tcattacaac aactggtttt ggatatggag atattaccaa ctggcccctc
    21481 ttctcccagt ttatcctcct tttcctcatg gcaatcggtg gctctgctgg atcaactgca
    21541 ggtggactca agattattcg aggcctcatc ctttcaaaaa ttgccaaaaa ccagattttg
    21601 tcaatcctat cgccccaccg tgttttgact ctccatgtga atcaaacggt gattgataaa
    21661 gatacccagc ataagattct caagtacttt gtcatctatg ctatgatttt gctagcgctt
    21721 atctttattg tcagcctaga tagcaatgat tttctggtcg tgaccagcgc tgtctttagc
    21781 tgtttcaata atatcgggcc tattctagga accacttcta gtttctcaat ctttagtcct
    21841 atctcaaaaa ttctcctctc ctttgcaatg attgcaggcc gcttggagat ttacccaatc
    21901 ctacttctct ttatgaagag aacttggtct aagagataaa atacaaaatc cctcttttta
    21961 caattgtgaa agagggattt ttatattaaa aagggggaac gtttttaaat ccaagcctgt
    22021 ctgtaagcaa agttcttact caaataaaag atggaaaaac ttactacaca gcttggtaat
    22081 gctccaatac aaattgtaag gctttacttg gattctttgt taaatgaata tattccattc
    22141 ctctggtagc aactatctga atacctaatc tttctgcatc caccttcatc tctctataat
    22201 aactccgaac ttgtggagcc agaataatta aatcataaac acccataata tcataatgag
    22261 ctccgtacgc tcctgaattc gcaatcactc taacttctgc taattgagcg ccctcgttaa
    22321 ttgcattggc taattacgca cttgttccag accctgcaca aagaaccagt actttcaact
    22381 ccttactttt tattacatct atctcaccag gcattatttc acttgtatcc tcctctaaaa
    22441 taatatcatt tgagcttgca atatctacaa cctgtagtaa atatctcgta tttagacaat
    22501 atgaaaacaa gacgacttcc atataggaaa ccgccttctc gctatgttgc atgaaactgt
    22561 aaaagtggat gaaattgata gcggtagtca gatcaagaga catcataact ctaaaaagtc
    22621 acaatatata agttcatcct cggaaaaata tcattctaat tgttgaaatg gatatataaa
    22681 caggggtatt aacattaaat gctcatgaaa caacgaatac aggtatcaaa actatgacaa
    22741 aacgagtccc taaatttact aaagacactg ctcaacttta cacctgtaaa tggttgttgt
    22801 ataataaagt tacaaagatg tacgaccaca ctgttgtaaa tcatagtgtt cgcgaatata
    22861 ttactgatag catttctaca aatacaattg aagagactgg ataggcttta aacgaaatat
    22921 gtcagtgttt tggcattcct agtcttcata tcatttaaag aattgtatag ataaaatttt
    22981 tcccaataca gacactcgta acaactgctt catttttcta ccaacatatt taggaacagg
    23041 ataagataca agaagattaa tccatagctc agttctatac caatctaaga caaataagct
    23101 aaaaaatgat tgataataag caaatagatt ccaaattttc tctatctgct cattttaata
    23161 aacaatacta gtgtaactat ccttccagtc agaaacttgt caaatcacac cgaaaactct
    23221 tctaaaattt atctcgttag gcaatcaagc aaaaactcga cgatagtaca aacattatta
    23281 tacagaattg acttcctaaa ttatatactt tagtaaggtt ttcggataag aaaaaaggtt
    23341 cattttacat ttctaaacat tcttttctaa gatgaaaaac agaatttttc gattgtgatt
    23401 taaagcaaca agaagatttt cagtgtcatc ctatagatac gagctaatta agaaaaacta
    23461 catttttgaa tataaactac aataatataa actaaatttt ataggaggaa gacaatggat
    23521 tggtacgatt atatgataca ggcatccaaa caatcacaat tcaacgcaag ccattggttt
    23581 cgctatttgc gaaaagttat ttttgaagac tattcttatt taacaaacca agatgtagaa
    23641 aagttgctag actccaaaga actaacccgt tttcaaaaaa ttagcttgaa gtatgccttt
    23701 caagagcata ctccaactca taaatatgtg atttcattaa ataaacctgc taagttaacc
    23761 aatgttcaaa aattgatgga gaaatacaaa catggataaa atgaaaccgg tcttccaagc
    23821 cctaaataag gaattaattc aggaaaatct gactttaaca attatctgtg tcgatggtta
    23881 tgtcttagaa tatcatggtt tacgtgccac acaagatgtt gatgcttttt atgaccaaaa
    23941 tcagaaaatc aatgaaatta ttgctcgtgt aggaaaacag tttaatctta acatccacga
    24001 agagttatgg ctcaacaatc atgttgcaaa gcaaatatga acaaacaacc tcccttaagt
    24061 ttatgcgaat ccttgtactc atttgagaat ctgaccgttt tagtagtccc tattgagtat
    24121 gtgttaggaa tgaagatgat gagtatcaga gagcaggatt tgcaagatat tggtgcaatt
    24181 attaaataca aaaactttca ttcaccattc gataccttta aatatttaaa agacatggaa
    24241 tttgatacta ttgacctctc tgttctatta gaaggtttta gttatgctta tggtatggat
    24301 tggttagaaa aattttttaa agaaaatcaa gataaacttc gcgaatttta ttaacagtat
    24361 caaacaagat gattgtcaat tagccagtcg tcttgttttt tatgatgaaa tgaaataaaa
    24421 tctgaacaaa tcgcttagag aattccagtc aatttctagc gctgtttgag acgtttcagt
    24481 ggactatagt aaaatgaaat aagaatagga caaatcgatc aggacagtca aatcgatttc
    24541 taagaatgtt ttagaaataa aggtgtacta ttctagtttc aatctattat atttcagatt
    24601 cggtccacta ttccttccca aaaacattgc atattgcgcc gaaggaattg ctcacactat
    24661 cccaagcaca aaaccctcag tcgtttgacc gagggttcct tttcattatt caagaacttg
    24721 attagctcaa tgcatccaag gcgtcatcca ttgaaagaac ttcgtggaag acacgttgtg
    24781 tcaattcagt tttttgttct ggagtgaggt atttagtgtt tacacagtat ccagagatac
    24841 gtacgataac gtcttcgcct gacatgattt tttcgtaaac atcgttcaag tccataacgt
    24901 tcaagttaac gtgttgtcca ccgttttcga agtaaccatc aaggattgtt accaagttat
    24961 caacttgttc atcacgagtc ttaccaagag cgcgaggtga tacttgtgta gtcaatgaga
    25021 taccgtcagc tgcataacta aagtcaaggc tagaaagtga gttcaagttt tgcaaccaac
    25081 cacctttagc tttgttagat gggttagcac ctggtgagaa gaattcaagt ttagacaagt
    25141 tcacagaacc atcttcgttg aggtatacac ctttgtgaac tggtgagtta ccagtttgtt
    25201 tagagtaagc aacgttagat gtgattgtca aaagtgatac tgtagcttct gcgtctttgt
    25261 atagtttgtg gctacgtaga cgagttgtgt aagcttcgat taaccattct gccaattcgt
    25321 ttgaacgtgg gtcatcttca ccccagcgtg ggtagtcacc gattgtttcg taatcgtaga
    25381 tgtagccatc ttcgtcacgg attggtttaa ctgtagcgta tttgatagct gacaatgtat
    25441 caacagtgtt agcaaatcca cagataccga atcccatgtt ggcacgttgt ttagttggca
    25501 agaaggccat ttgaacagct tcgtagttgt acctatcagt catgtagtgg atgatgttca
    25561 aggcatctac gtaagtgtca gtcaaccagt caagagattt ttcaaagttc gctttaactg
    25621 attcaaattc aagaacttcg tcacggattg gttcgatatc aaatactttg tagtctttgt
    25681 gaacatcgtc gtaaccacca ttcaaaccag taagaagggc tttaagaacg tttacacgag
    25741 caccgaagta ctggatgttg tggcgttgtt cttcattttc tggatcaagt ggagacacac
    25801 agcatgagat acagctcatt tcaccatatc cgtctttagc cattgttgtt acaccttcgt
    25861 attggataga agagtgtttg tggctcatgt gcatacagta gcgacggaag ttgtatggca
    25921 atttgtcagt ccaaagaact gtcaagtttg gttctggtga gttaccgatg ttgtcaagag
    25981 tgttcaagaa acggtagtcc atcttagtaa cacggtgacg accgtcgtta cccataccag
    26041 ccatagaagt tgtgataaag gttgggtcac ctgagtacaa ttggtcataa gcttttgtac
    26101 gagcaaattt aactgtacga agtttcataa cgaaatcatc aacgaattct tggatttctg
    26161 attcagtaaa tgtaccacga gcaaggtcac gttctgcaaa gatgtccaat acgattggta
    26221 cacgacctag agatgtagca gcaccgttaa tcacacggca gacagccatg aaagcaatgt
    26281 taacccattg gattgcttct ttcacgttca tcgctggttt gcgaacatca accccgtaaa
    26341 ggtcacccag gcgaacaact tgttgcaatg cttggtattg aaggtttact tcttcacgaa
    26401 gacggattgt ttcttcatcg atttctttga ttgcattcca gtcatttact ttttcttgca
    26461 tcaagtagtc tgcaccgtaa agagcaagac gtgcgtaaac accgatgata cgtccgcgtg
    26521 agtatgcatc tggaagacca gttacagtgt gtgcgtgacg agcgcgacga atatttgaag
    26581 tgtaggcacg gaaaataccg tcgttaactg ttgttacata tttagtgaag atttcgtgaa
    26641 cagctgggtc tggttcgtat ccattttctt tcaaagtagt ttcagccata cggataccac
    26701 cttttggcat gaagttcaat ttgaagagtt catcgttttg gataccgaag ataacttcat
    26761 tttctttgtc gataaatcca gcagggatat cagcgataga tgttggacga gtgtccattg
    26821 ggaaacgagt ttcttcgtag tgtgctttag tttcttctac aattttcttg atgtgaagtg
    26881 aacgctctgt tggtcctgca aggaagcttt cgtctccatc ataaggtgtg tagttagctt
    26941 gtacaaatcg tgatacactt gctttttctt tccaatctac gcctttgaag ccttcccaag
    27001 ctttgtcaaa aatatcttgt gcttcaacaa ctgtcttaac aaccatatta atgtcctctt
    27061 ttttctagta acagtcatct gttacattca taagacaagt ataccatata gtaaccgatt
    27121 tcaacaagtg aaaattccct atttttacac tttcttttct aaaacagtct atattttatt
    27181 tcaaactgta ttatattttt gaaaaaataa agtccttttt tctttttttc agaaaaaagg
    27241 gtataataaa agaaaataag cagtaacact caatggaaat cgaa
//
LOCUS       DBERPV010000025        26386 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.25, whole genome shotgun sequence.
ACCESSION   DBERPV010000025 DBERPV010000000
VERSION     DBERPV010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 26386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26386
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.25"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..899
                     /gene="lytB"
                     /locus_tag="ACL8C7_001393"
     CDS             <1..899
                     /gene="lytB"
                     /locus_tag="ACL8C7_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HGS1395575.1"
                     /translation="KNETVDGYQLGSDGKWLGGKATNENAAYYQVVPVTANVYDSDGE
                     KLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYESDGH
                     RFYHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNYSAE
                     ELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKDKNN
                     FFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEYASD
                     PYWGEKIASVMMKINEKLGGKD"
     gene            complement(960..2615)
                     /gene="pavA"
                     /locus_tag="ACL8C7_001394"
     CDS             complement(960..2615)
                     /gene="pavA"
                     /locus_tag="ACL8C7_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HGS1395576.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            2720..3217
                     /gene="ybeY"
                     /locus_tag="ACL8C7_001395"
     CDS             2720..3217
                     /gene="ybeY"
                     /locus_tag="ACL8C7_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HGS1395577.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            3198..3593
                     /locus_tag="ACL8C7_001396"
     CDS             3198..3593
                     /locus_tag="ACL8C7_001396"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGS1395578.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFALTGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            3610..4509
                     /gene="era"
                     /locus_tag="ACL8C7_001397"
     CDS             3610..4509
                     /gene="era"
                     /locus_tag="ACL8C7_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HGS1395579.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            4558..5382
                     /gene="mutM"
                     /locus_tag="ACL8C7_001398"
     CDS             4558..5382
                     /gene="mutM"
                     /locus_tag="ACL8C7_001398"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HGS1395580.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQEPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQAALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQIYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            5382..5987
                     /gene="coaE"
                     /locus_tag="ACL8C7_001399"
     CDS             5382..5987
                     /gene="coaE"
                     /locus_tag="ACL8C7_001399"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HGS1395581.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSNQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRYAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            5974..7173
                     /locus_tag="ACL8C7_001400"
     CDS             5974..7173
                     /locus_tag="ACL8C7_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter PmrA"
                     /protein_id="HGS1395582.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            7173..7322
                     /gene="rpmG"
                     /locus_tag="ACL8C7_001401"
     CDS             7173..7322
                     /gene="rpmG"
                     /locus_tag="ACL8C7_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGS1395583.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            7362..7595
                     /gene="secG"
                     /locus_tag="ACL8C7_001402"
     CDS             7362..7595
                     /gene="secG"
                     /locus_tag="ACL8C7_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HGS1395584.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            7697..10051
                     /gene="rnr"
                     /locus_tag="ACL8C7_001403"
     CDS             7697..10051
                     /gene="rnr"
                     /locus_tag="ACL8C7_001403"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HGS1395585.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEAKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEIIFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            10014..10481
                     /gene="smpB"
                     /locus_tag="ACL8C7_001404"
     CDS             10014..10481
                     /gene="smpB"
                     /locus_tag="ACL8C7_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HGS1395586.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            10497..11357
                     /gene="tehB"
                     /locus_tag="ACL8C7_001405"
     CDS             10497..11357
                     /gene="tehB"
                     /locus_tag="ACL8C7_001405"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0046690 - response to tellurium ion
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HGS1395587.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTKPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDIPVDLYDINSASIGQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            11430..12383
                     /gene="coiA"
                     /locus_tag="ACL8C7_001406"
     CDS             11430..12383
                     /gene="coiA"
                     /locus_tag="ACL8C7_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HGS1395588.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQIHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYKVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            12402..14204
                     /gene="pepF"
                     /locus_tag="ACL8C7_001407"
     CDS             12402..14204
                     /gene="pepF"
                     /locus_tag="ACL8C7_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HGS1395589.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQIEKLYVYAHMKNDQDTREAKYQEYYAKAMTFYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            14206..14919
                     /locus_tag="ACL8C7_001408"
     CDS             14206..14919
                     /locus_tag="ACL8C7_001408"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HGS1395590.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            14986..15927
                     /gene="prsA"
                     /locus_tag="ACL8C7_001409"
     CDS             14986..15927
                     /gene="prsA"
                     /locus_tag="ACL8C7_001409"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HGS1395591.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKSNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(16046..16387)
                     /locus_tag="ACL8C7_001410"
                     /pseudo
     CDS             complement(16046..16387)
                     /locus_tag="ACL8C7_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            16800..16895
                     /locus_tag="ACL8C7_001411"
                     /pseudo
     CDS             16800..16895
                     /locus_tag="ACL8C7_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(17148..17768)
                     /locus_tag="ACL8C7_001412"
     CDS             complement(17148..17768)
                     /locus_tag="ACL8C7_001412"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGS1395592.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTPNTWNDTSYQS"
     gene            complement(17768..18250)
                     /locus_tag="ACL8C7_001413"
     CDS             complement(17768..18250)
                     /locus_tag="ACL8C7_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HGS1395593.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMILQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDQMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(18250..19092)
                     /locus_tag="ACL8C7_001414"
     CDS             complement(18250..19092)
                     /locus_tag="ACL8C7_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HGS1395594.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDFKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDFLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(19187..19987)
                     /locus_tag="ACL8C7_001415"
     CDS             complement(19187..19987)
                     /locus_tag="ACL8C7_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HGS1395595.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            20131..21510
                     /gene="glmU"
                     /locus_tag="ACL8C7_001416"
     CDS             20131..21510
                     /gene="glmU"
                     /locus_tag="ACL8C7_001416"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002899862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HGS1395596.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAEQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVILKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            21520..22065
                     /locus_tag="ACL8C7_001417"
     CDS             21520..22065
                     /locus_tag="ACL8C7_001417"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGS1395597.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTARRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            22077..22391
                     /gene="macP"
                     /locus_tag="ACL8C7_001418"
     CDS             22077..22391
                     /gene="macP"
                     /locus_tag="ACL8C7_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HGS1395598.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            22408..23100
                     /locus_tag="ACL8C7_001419"
     CDS             22408..23100
                     /locus_tag="ACL8C7_001419"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HGS1395599.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNTQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHTLNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLAFLKALD"
     gene            23177..23668
                     /gene="rocS"
                     /locus_tag="ACL8C7_001420"
     CDS             23177..23668
                     /gene="rocS"
                     /locus_tag="ACL8C7_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HGS1395600.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            23766..24356
                     /locus_tag="ACL8C7_001421"
     CDS             23766..24356
                     /locus_tag="ACL8C7_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HGS1395601.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            24365..26128
                     /locus_tag="ACL8C7_001422"
     CDS             24365..26128
                     /locus_tag="ACL8C7_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HGS1395602.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDRYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         8027 a         4798 c         5780 g         7781 t
ORIGIN      
        1 cgaaaaatga gacagtagat ggttatcagc ttggaagcga tggtaaatgg cttggaggaa
       61 aagctacaaa tgaaaatgct gcttactatc aagtagtgcc tgtcacagcc aatgtttatg
      121 attcagatgg tgaaaagctt tcctatatat cgcaaggtag tgtcgtatgg ctagataagg
      181 atagaaaaag tgatgacaag cgcttggcta ttactatttc tggtttgtca ggctatatga
      241 aaacagaaga tttacaagcg ctagatgcta gtaaggactt tatcccttat tatgagagtg
      301 atggccaccg tttttatcac tatgtggctc agaatgctag tatcccagta gcttctcatc
      361 tttctgatat ggaagtaggc aagaaatatt attcggcaga tggcctgcat tttgatggtt
      421 ttaagcttga gaatcccttc cttttcaaag atttaacaga ggctacaaac tacagtgctg
      481 aagaattgga taaggtattt agtttgctaa acattaacaa tagccttttg gagaacaagg
      541 gcgctacttt taaggaagcc gaagaacatt accatatcaa tgctctttat ctccttgccc
      601 atagtgccct agaaagtaac tggggaagaa gtaaaattgc caaagataag aataatttct
      661 ttggcattac agcctatgat acgacccctt acctttctgc taagacattt gatgatgtgg
      721 ataagggaat tttaggtgca accaagtgga ttaaggaaaa ttatatcgat aggggaagaa
      781 ctttccttgg aaacaaggct tctggtatga atgtggaata tgcttcagac ccttattggg
      841 gcgaaaaaat tgctagtgtg atgatgaaaa tcaatgagaa gctaggtggc aaagattagt
      901 actataagtg aatatgattt gagtgaatag taagttaaaa atcctgattt caagtaaaat
      961 caggattttt tcatggatgc aatttttttg gagtctggtg tgacgcggag ggtcttttgt
     1021 cctgtgtaag tgacaaagcc gggttttcca ccagttggtt tattgagttt tttgacttca
     1081 atcatatcta cctgcaccag attcgacagg cgcccttgag agaagtaggc agctaactct
     1141 gctgcgtctg tcttgactgc atcagatggg tcaagatttc ctgagatgac aacatggctt
     1201 ccaggaatgt ccttagcatg gaaccaaagt tcctccttgc gggccatttt aaaggtcaat
     1261 tcctcatttt gaagattgtt tcgtccgaca tagatgatgg ttttgccatc gcttgctaga
     1321 tattgttcta gttttttgcg tttctggatt ttctcccgtt gtcttctgcg gataaaacct
     1381 gtttgaatca attcttcacg gatttcagcg atttcttcca gtccagcttg gttgaggacg
     1441 gtttctacac tttccagata gagaatagtg gctttggttt cttcaatcaa atcagtcaag
     1501 tatttgacag cttctttgag tttctgatac cgtttaaaat agcgttgggc attctggttg
     1561 ggagtcagag ccttatcaag cgcaatcatg ataggttggt tggtatagta gttgtctagg
     1621 ataacctggt cttggtcgtt aggcacttgg tggaggaagg ttgtcagcaa ttctcctttt
     1681 tgacgaaatt cttcagcgtt gtctgtcgcc agtaactctt tttcctgttt tttgagtttg
     1741 tgtcggtttt tctgaagttc attttcaaca cgacgaatca gttcactggc ctgctgtttg
     1801 acgcggtcgc gctcagcctt atccttatag taggtgtcca acaaatcaga aagatttgca
     1861 aaaggctctc ccacctgatt tgcaaaagga actggactga aggaagtctc agtcaagcat
     1921 ggcttggttt cttgattgaa aaaatttcgg aaagcggaaa gtttttcact aaccagtatc
     1981 ctttccaatt catttgccgt atcgcgtccc agaccttgaa agaggctttg aagatttttt
     2041 gctgttagtt cttgggtttg caggatttca aagagctttt catccttgat agtaaaagga
     2101 ttgagagatt ttgtacttgg cggagcgata taggtcgatc ctggaagtaa ggtgcggtag
     2161 ctattttgtg aaaagccgac gtgtttgata acttcgagga ttttatgact gcttttatcg
     2221 accagtagaa tattactgtg tttccccata atttcgataa tcaaggtagc ctggatatgg
     2281 tctccaatct cgtttttatt ggaaactgta atttccacaa tacggtcatt ttccacttgc
     2341 tcaatcgact caatcagggc cccctgcaaa tactttctca aaaccatgat aaaggtagaa
     2401 ggttgggctg gattttcaaa agtcgtttgg gttagctgaa tgcgtccaaa aactggatgg
     2461 gcagaaagga gcaggcgatg gctttggcga ttgctgcgga tttgcaagac caactcttgt
     2521 tcaaaaggct gattgatttt ctggatgcga ccattcacta attcgcttcg caattcctca
     2581 actatgtggt gtaaaaaaaa tccgtcaaat gacatcgttc tctccttgtg attgtattcc
     2641 atagtattat atcaaaaagg tagaataaaa tcatggaaat gtggtataat aaagccaagt
     2701 aaagagaaac gagaagcaca tgtatattga aatggtagat gaaactggtc aagtttcaaa
     2761 agaaatgttg caacaaaccc aagaaatttt ggaatttgca gcccaaaaat taggaaaaga
     2821 agacaaggag atggcagtca cttttgtgac caatgagcgt agtcatgaac ttaatctgga
     2881 gtaccgtgac accgaccgtc cgacagatgt catcagcctt gagtataaac cagaattgga
     2941 aattgccttt gacgaagagg atttgcttga aaatccagaa ttggcagaga tgatgtctga
     3001 gtttgatgcc tatattgggg aattgttcat ctctatcgat aaggctcatg agcaggctga
     3061 agaatatggt cacagctttg agcgtgagat gggcttcttg gcagtacacg gctttttaca
     3121 tattaacggc tatgatcact acactccgga agaagaagcg gagatgttcg gtttacaaga
     3181 agaaattttg acagcctatg gactcacaag acaataaacg aaaatggaaa aatcgtgact
     3241 tgatatccag tttagaattt gctttgacag gtatttttac tgctatcaag gaagaacgca
     3301 atatgcgaaa acacgcagtg acggctctag tggtcatcct tgcaggtttt gtttttcagg
     3361 tgtcacgaat cgaatggctc tttctcctat tgagcatttt cttggtggta gcctttgaaa
     3421 ttatcaattc tgctatcgaa aatgtggtgg atttggccag tcactatcac ttttccatgc
     3481 tggctaaaaa tgccaaggat atggcggctg gcgcggtatt agtggtttct ctttttgcag
     3541 ccttaacagg cgcattgatt tttctcccac gaatctggga tttattattt taaacagtaa
     3601 gaggaaatta tgacttttaa atcaggcttt gtagccattt taggacgtcc caatgttggg
     3661 aagtcaacct ttttaaatca cgttatgggg caaaagattg ccatcatgag tgacaaggcg
     3721 cagacaacgc gcaataaaat catgggaatt tacacgactg ataaggagca aattgtcttt
     3781 atcgacacac cagggattca caaacctaaa acagctctcg gagatttcat ggttgagtct
     3841 gcctacagta cccttcgcga agtggacact gttcttttca tggtgcctgc tgatgaagcg
     3901 cgtggtaagg gggacgatat gattatcgag cgtctcaagg ctgccaaggt tcctgtgatt
     3961 ttggtggtga ataaaatcga taaggtccat ccagaccagc tcttgtctca gattgatgac
     4021 ttccgtaatc aaatggactt taaggaaatt gttccaatct cagcccttca gggaaataac
     4081 gtgtctcgtc tagtggatat tttgagtgaa aatctggatg aaggtttcca atatttcccg
     4141 tctgatcaaa tcacagacca tccagaacgt ttcttagttt cagaaatggt tcgcgagaaa
     4201 gtcttgcacc taactcgtga agagattccg cattctgtag cagtagttgt tgactctatg
     4261 aaacgagacg aagagacaga caaggttcat atccgtgcaa ccatcatggt cgagcgcgat
     4321 agccaaaaag ggattatcat cggtaaaggt ggcgctatgc ttaagaaaat cggtagcatg
     4381 gcccgtcgtg atatcgaact catgctagga gacaaggtct tcctagaaac ctgggtcaag
     4441 gtcaagaaaa actggcgcga taaaaagcta gatttggctg actttggcta taatgaaaga
     4501 gaatactaag tagaggtagg ctcatgcctg cttcttgttt ttacagaagg aggacttatg
     4561 cctgaattac ctgaggttga aaccgtttgt cgtggcttag aaaaattgat tataggaaag
     4621 aagatttcga gtatagaaat tcgctacccc aagatgatta agacggattt ggaagagttt
     4681 caaagggaat tgcctagtca gattatcgag tcaatgggac gtcgtggaaa atatttgctt
     4741 ttttatctga cagacaaggt cttgatttcc catttgcgga tggagggcaa gtatttttac
     4801 tatccagacc aagaacctga acgcaagcat gcccatgttt tctttcattt tgaagatggt
     4861 ggcacgcttg tttatgagga tgttcgcaag tttggaacca tggaactctt ggtgcctgac
     4921 cttttagacg cctactttat ttctaaaaaa ttaggtcctg aaccaagcga acaagacttt
     4981 gatttacagg tctttcaagc tgcccttgcc aagtccaaaa agcctatcaa atcccatctc
     5041 ctagaccaga ccttggtagc tggacttggc aatatctatg tggatgaggt tctctggcga
     5101 gctcaggttc atccagctag accttcccag actttgacag cagaagaagc gactgccatt
     5161 catgaccaga ccattgctgt tttgggccag gctgttgaaa aaggtggctc caccattcgg
     5221 acttatacca atgcctttgg ggaagatgga agcatgcagg actttcatca gatctatgat
     5281 aagactggtc aagaatgtgt acgctgtggt accatcattg agaaaattca actaggcgga
     5341 cgtggaaccc acttttgtcc aaactgtcaa aggagggact gatgggaaaa atcatcggaa
     5401 tcactggggg aattgcctca ggtaagtcaa ctgtgacaaa ttttctaaga cagcaaggct
     5461 ttcaagcagt ggatgccgac gcagtcgtcc accaactaca gaaacctggt ggtcgtctgt
     5521 ttgaggctct agtacagcac tttgggcaag aaatcattct tgaaaacgga gaactcaatc
     5581 gccctctcct agctagtctc atcttttcaa atcctgaaga gcaaaaatgg tctaatcaaa
     5641 ttcaagggga gattatccgt gaggaactgg ctactttgag agaacagttg gctcagacag
     5701 aagagatttt cttcatggat attcccctac tttttgagca ggactacagc gattggtttg
     5761 ctgagacttg gttggtctat gtggaccgat atgcccaagt agaacgctta atgaaaaggg
     5821 accagttgtc caaagatgaa gctgagtctc gtctggcagc ccagtggcct ttagaaaaaa
     5881 agaaagattt ggccagccag gttcttgata ataatggcaa tcagaaccag cttcttaatc
     5941 aagtgcatat ccttcttgag ggaggtaggc aagatgacag agattaactg gaaggataat
     6001 ctgcgtattg cctggtttgg taattttctg acaggagcca gtatttcttt ggttgtacct
     6061 tttatgccca tcttcgtgga aaatctaggt gtagggagtc agcaagtcgc tttttatgca
     6121 ggcttagcaa tttctgtctc tgctatttcc gcggcgctct tttctcctat ttggggtatt
     6181 cttgctgaca aatacggccg aaaacccatg atgattcggg caggtcttgc tatgactatc
     6241 actatgggag gcttggcctt tgtcccaaat atctattggt taatctttct tcgtttacta
     6301 aacggtgtat ttgcaggttt tgttcctaat gcaacggcac tgatagccag tcaggttcca
     6361 aaggagaaat caggctctgc cttaggtact ttgtctacag gcgtagttgc aggtactcta
     6421 actggtccct ttattggtgg ctttatcgca gaattatttg gcattcgtac agttttctta
     6481 ctggttggta gttttctatt tttagctgct attttgacta tttgctttat caaggaagat
     6541 tttcaaccag tagccaagga aaaggctatt ccaacaaagg aattatttac ctcggttaaa
     6601 tatccctatc ttttgctcaa tctcttttta accagttttg tcatccaatt ttcagctcaa
     6661 tcgattggcc ctattttggc tctttatgta cgcgacttag ggcagacaga gaatcttctt
     6721 tttgtctctg gtttgattgt gtccagtatg ggcttttcca gcatgatgag tgcaggagtt
     6781 atgggaaagc taggtgacaa ggtgggcaat catcgtctct tggttgtcgc ccaattttat
     6841 tcagtcatca tctatctcct ctgtgccaat gcctctagcc cccttcaact aggactctat
     6901 cgattcctct ttggcttggg aaccggtgcc ttgattcccg gggttaatgc cctactcagc
     6961 aaaatgactc ccaaagccgg catttcgagg gtctttgcct tcaatcaggt attcttttat
     7021 ctgggaggtg ttgttggtcc catggcaggt tctgcagtag caggtcaatt tggctaccat
     7081 gctgtctttt atgcgacgag cctttgtgtt gcctttagtt gtctctttaa cctgattcaa
     7141 tttcgaacat tattaaaagt aaaggaaatc tagtgcgagt aaaaatcaat ctcaaatgct
     7201 cctcttgtgg cagtatcaat tacctaacca gtaaaaattc aaaaacccat ccagacaaga
     7261 ttgaggtttt aaagtattgt cccaaggaaa gaaaagtaac cctacatctt gaatctaagt
     7321 agattttatg gtaaaataat agggatttta aggagtttga tatgtataac ctattattaa
     7381 ccattttatt agtattatct gttgtgattg tgattgcaat tttcatgcaa ccaaccaaaa
     7441 accaatccag caatgtattt gatgccagtt caggtgattt gtttgaacgc agtaaagctc
     7501 gcggttttga agctgtaatg cagcgtttga cagggatttt agtctttttc tggctagcca
     7561 ttgccttagc attgacggta ttatcaagta gataagaaaa taatgggcag gactaggtct
     7621 ttgcctcttt ttatttttaa aggatgtttg agaaggtttt acagtaaaag aaaattaaaa
     7681 aatctagaaa gaaaatatga aagatagaat aaaagaatat ttacaagaca agggaaaggt
     7741 gactgttaat gatttggctc aggctttggg aaaagacagt tccaaggatt ttcgtgagtt
     7801 gattaaaacc ttgtccttaa tggaaagaaa gcaccagatt cgctttgaag aagatggcag
     7861 tctgaccttg gaagccaaga aaaaacatga gattaccctc aaggggattt ttcatgccca
     7921 taaaaatggt tttggttttg tcagcctaga aggggaagag gacgaccttt ttgtagggaa
     7981 aaatgatgtc aactatgcta ttgatggtga taccgtcgag gtagtgatta agaaagtcgc
     8041 tgaccgcaat aagggaacag cagcagaagc caaaattatt gatatcctag aacacagttt
     8101 gacaacagtt gtcgggcaaa tcgttctgga tcaggaaaag cctaagtatg ctggctatat
     8161 tcgttcaaaa aatcagaaaa tcagtcaacc gatttatgtt aagaaaccag ccctaaagtt
     8221 agaaggaaca gaagttctca aggtctttat cgataaatac ccaagcaaga aacatgattt
     8281 ctttgtcgcg agtgttctcg atgtggtggg acactcaacg gatgtcggaa ttgatgttct
     8341 tgaggttttg gaatcaatgg acattgtatc cgagtttcca gaagctgttg ttaaggaagc
     8401 agaaagtgtg cctgatgctc cgtctcaaaa ggatatggaa ggtcgtctgg atctaagaga
     8461 tgaaattatc tttaccattg acggtgcgga tgccaaggac ttggacgatg cagtgcatat
     8521 caaggctctg aaaaatggca atctggagct tggggttcac atcgcagatg tttcttatta
     8581 tgtgaccgag gggtctgccc ttgacaagga agcccttaac cgtgcgactt ctgtttacgt
     8641 gacagaccga gtggtgccaa tgcttccaga acgactatca aatggcatct gctctctcaa
     8701 tccccaagtt gaccgcctga cccagtctgc tattatggag attgataaac atggtcgtgt
     8761 ggtcaactat accattacac aaacagttat caagaccagt tttcgtatga cctatagcga
     8821 tgtcaatgat atcctagctg gcgatgaaga aaagagaaaa gaataccata aaattgtacc
     8881 aagtatcgaa ctcatggcca agcttcatga aactttagaa aacatgcgtg tgaaacgtgg
     8941 agctctcaat tttgatacca atgaagcgaa gattttagtg gataaacaag gtaagcctgt
     9001 tgatatcgtt cttcggcagc gtggcattgc cgagcggatg attgagtctt ttatgttgat
     9061 ggctaatgaa acagttgccg aacatttcag caagttggat ttgcctttta tctaccgaat
     9121 tcacgaggag cctaaggctg aaaaggttca gaagtttatt gattatgctt cgagttttgg
     9181 cttgcgcatt tatgggactg ccagtgagat tagccaggag gcacttcaag acatcatgcg
     9241 tgctgttgag ggagaacctt atgcagatgt attgtccatg atgcttcttc gctctatgca
     9301 gcaggctcgt tattcggagc acaatcacgg ccactatgga ctagctgctg actattatac
     9361 tcactttacc agtccaattc gtcgttatcc agaccttctt gttcaccgta tgattcggga
     9421 ttacggccgt tctaaggaaa tagcagagca ttttgaacaa gtgattccag agattgcgac
     9481 ccagtcttcc aaccgtgaac gtcgtgctat agaagctgag cgtgaagtcg aagccatgaa
     9541 aaaggctgag tatatggaag aatacgtggg tgaagagtat gatgcagttg tatcaagtat
     9601 tgtcaaattc ggtctctttg tcgaattgcc aaacacagtt gaaggcttga ttcacatcac
     9661 taatctacct gaattttatc atttcaatga gcgtgatttg actcttcgtg gagaaaaatc
     9721 aggtatcact ttccgagtgg gtcagcagat ccgtatccgt gttgaaagag cggataaaat
     9781 gactggagag attgattttt cattcgtacc tagtgagttt gatgtgattg aaaaaggctt
     9841 gaaacagtct agtcgtagtg gcagagggcg tggttcaaat cgtcgttcgg ataagaagga
     9901 agacaagaga aaatcaggac gctcaaatga taagcgtaaa cattcacaaa aagacaagaa
     9961 gaaaaaagga aagaaacctt tttacaagga agtagctaag aaaggagcca agcatggcaa
    10021 agggcgaggg aaaggtcgtc gcacaaaata aaaaggcacg ccacgactat acaatcgtag
    10081 atacgctaga ggcagggatg gtcctgactg gaactgaaat caagagtgta cgagctgctc
    10141 gaattaatct caaggatggc tttgctcaag tgaaaaatgg agaagtttgg ctgagcaatg
    10201 ttcatatcgc accttacgaa gagggcaata tctggaacca ggaaccagaa cgtcgtcgta
    10261 aactcctgct ccataaaaag caaattcaaa aattggaaca agagaccaaa gggacaggaa
    10321 tgaccttagt tccccttaag gtctatataa aagatggcta cgctaagctt cttttaggac
    10381 ttgccaaagg gaagcatgac tatgacaaac gggagtctat caaacgtcgt gagcaaaatc
    10441 gagatatcgc gcgtgtgatg aaagctgtta atcagcgata aaaagaggaa ttgaaaatgg
    10501 aaaaattagt tgcctataaa cgcatgcctt tgtggaataa acaaacaatg cctgaagctg
    10561 ttcagcaaaa gcacaataca aaagttggga cttgggggaa aattactgtc ttgaagggag
    10621 ctctcaagtt tattgaattg acagaagaag gggaagttct agctgaacac ctctttgaag
    10681 caggggcaga caatccaatg gcccaacctc aagcctggca ccgagtggaa gctgccacag
    10741 atgatgtgga atggtacttg gaattttatt gtaaacctga ggattatttt gctaaaaaat
    10801 acaataccaa acctgttcat tcagaggtcc tagaggccat gcagacagtg aaacaaggga
    10861 aagctttgga tttgggttgt ggtcaggggc gtaattctct ttttctagcc cagcaagatt
    10921 ttgatgtgac ggctgtagat caaaatggac tggctcttga aatcttgcaa agcattgtgg
    10981 agcaggaaga tttggacata cctgttgacc tttacgatat caattcagct agcattggac
    11041 aagaatatga ttttatcgtt tcaacagttg ttctcatgtt tctacaagcg gaccgcattc
    11101 cagctattat tcaaaatatg caggagaaaa ccagtgttgg tggttacaac cttatcgttt
    11161 gtgccatgga cacggaggac tatccttgct cggttaactt cccattcacc tttaaagaag
    11221 gagaactggc agactattac aaggattggg aattggttaa gtacaatgaa aatccaggcc
    11281 atttgcatcg tcgcgatgag aatggcaatc gtattcaact acgctttgcg actttactag
    11341 ctaagaaaat caagtaaaca cacatgaaga ttaggaattt tcctgatctt ttttcttttt
    11401 tacgaatgat atagaaaagg agggaattca tgtttgttgc gagagatgct aggggagaat
    11461 tggtaaatgt gttagaggat aaacttgaga agcaagcata cacctgccca gcttgtggag
    11521 gccagatcca tttgcgtcaa ggaccaagtg tacggacgca ttttgcccat aaatccttaa
    11581 aagactgtga ttttttcttt gaaaatgaaa gtccagaaca cctggccaat aaggaatccc
    11641 tctatcactg gttgaaaaaa gagacaaagg ttcaattaga gtacccgctt tcagaactta
    11701 aacagattgc ggatgtattt gtaaatggca atctagctct agaagttcag tgtagtccct
    11761 tgcctcagaa agtccttaaa gagcgaagtg agggctatcg tagtcagggt tacaaagtac
    11821 tgtggttgct gggtcaaaaa ctgtggctca aggagcgttt gactcgtcta cagcaaggtt
    11881 ttctgtattt cagtcaaaac atgggctttt atgtttggga attagacaag gaaaaacaag
    11941 ttttaagact caaatacctg atttaccagg atctccgcgg taaactccat tatcaaatca
    12001 aggaattttc ctatggtcaa ggtagtttat tggaaatatt gcgtcttccc tataagagac
    12061 aaaaaatatc tcattttaca gtttctgagg acaaggacat ctgtcgctat atccggcaac
    12121 aactttatta tcaaaatctc ttttggatga aagaacaagc agaagcctat caaaagggag
    12181 aaaatatcct gacttatggg ctgaaagaat ggtatccaca aattcgacca atagtgggca
    12241 aatttttcca gattgaacaa gacttgacta gctattatca gcatttttat acctattacc
    12301 aaaaaaatcc tcaaaatgat tggcaaaagc tttatccacc agccttttat cagcaatatt
    12361 tcttgaaaaa tatggtagaa tagaaaggat ggaggaatct aatggtatta caaagaaatg
    12421 aaataaatga aaaagataca tgggatctat caacgatcta cccaactgac caggcttggg
    12481 aagaagcctt aaaagattta acagaacaat tggagacagt agcccagtat gaaggccatc
    12541 tcttggatag tgcggataac ctactagaaa tcactgaatt ttctcttgaa atggaacgcc
    12601 agatagagaa gctttacgtt tatgctcata tgaagaatga ccaggataca cgtgaagcta
    12661 agtatcaaga gtactatgcc aaggccatga cattctacag ccagttagac caagcctttt
    12721 cattctatga gcctgaattt atggagatta gcgaaaagca gtatgctgac tttttagaag
    12781 ctcaaccaaa gctgcaggtt tatcaacact attttgacaa gctcttgcaa ggcaaggatc
    12841 acgttctttc acaacgtgaa gaagaattat tggctggagc tggagaaatc tttggttcag
    12901 caagtgaaac cttcgctatc ttggacaatg cggatattgt gttcccttat gtcctagacg
    12961 atgatggtaa agaagttcag ctatctcatg ggacttacac acgtttgatg gagtctaaaa
    13021 aacgtgaggt tcgccgtggt gcctatcaag ctctttatgc gacttacgaa caattccaac
    13081 acacctatgc caaaaccttg caaaccaatg ttaaggtgca aaattaccgt gctaaagttc
    13141 gtaactacaa gagtgctcgt catgcagccc tcgcagcgaa ttttgttcca gaaagtgttt
    13201 atgacaattt ggtagcagca gttcgcaagc atttgccact cttacatcgc tatcttgagc
    13261 ttcgttcaaa aatcttgggg atttcagatc tcaagatgta cgatgtctac acaccgcttt
    13321 catctgttga atacagtttt acctaccaag aagccttgaa aaaagcagaa gatgctttgg
    13381 cagtcttggg tgaggattac ttgagccgtg ttaaacgtgc cttcagcgag cgttggattg
    13441 atgtttacga aaatcaaggc aagcgttcag gtgcctactc tggtggttct tacgatacca
    13501 atgcctttat gcttctcaac tggcaagaca atctggacaa tctctttact cttgttcatg
    13561 aaacaggtca cagtatgcat tcaagctata ctcgtgaaac tcagccttat gtttacgggg
    13621 attactctat ctttttggct gagattgcct caactaccaa tgaaaatatc ttgacggaga
    13681 aattattgga agaagtggaa gacgacgcaa cacgctttgc tattctcaat aacttcctag
    13741 atggtttccg tggaacagtt ttccgccaaa ctcaatttgc tgagtttgaa cacgccattc
    13801 accaagcaga tcaaaatggg gaggtcttga caagcgattt cctaaataaa ctctacgcag
    13861 acttgaacca agagtattat ggtttgagta aggaagacaa tcctgaaatc caatacgagt
    13921 gggctcgcat tccacacttc tactataact actatgtata tcaatattca actggctttg
    13981 cggccgcctc agccttggct gaaaaaattg tccatggtag tcaagaagac cgtgaccgct
    14041 atatcgacta cctcaaggca ggtaagtcgg actatccact taatgtcatg agaaaagctg
    14101 gtgttgatat ggagaaggaa gactacctca acgatgcctt tgcagtcttt gaacgccgtt
    14161 taaatgagtt tgaagccctt gttgaaaaat taggattggc ataaaatggt tgaatcgtat
    14221 agtaagaatg ctaaccataa catgcgtcgt cctgtcgtca aagaagaaat tgtagacttg
    14281 atgcgtcagc gtcaaaagca ggtcacaggt ttcttgaaag aattggaaga ctttgcccgc
    14341 aaggaaaata ttcctattat tccccatgaa acggttgctt atttccgttt tcttatggaa
    14401 accatgcagc ctaaaaatat tctggaaatt gggacggcta tcggtttttc agctctcttg
    14461 atggctgaac atgcgccaaa tgctaagatt acaactattg atcgtaatcc agaaatgatt
    14521 ggttttgcca aggaaaattt tgcccagttt gacagtcgca agcaaatcac tctcctagag
    14581 ggagatgcgg tggatgtctt atctacactg acagagtctt atgatttcgt ctttatggat
    14641 tctgccaagt ctaaatacat cgtctttctg ccagaaatcc tcaaacattt ggaagttggt
    14701 ggtgtggttg tcttggatga tatttttcaa ggtggtgatg ttgccaagga tattatggaa
    14761 gtccgtcgtg gtcagcgaac catttatcga ggccttcaaa aattatttga tgcaacctta
    14821 gacaatccag aactcaccgc aacattagtg cctttaggag atggtattct catgcttcgt
    14881 aaaaatgtag cagatgttca actgtctgaa agcgaatgat tttcagaaaa atttaagaaa
    14941 aaatagtaaa atagatagag taacacttat ctcaaaggag tagacatgaa gaaaaaatta
    15001 ttggcaggtg ccatcacact attatcagta gcaactttag cagcttgttc gaaagggtca
    15061 gaaggtgcag accttatcag catgaaaggg gatgtcatta cagaacatca attttatgag
    15121 caagtgaaaa gcaacccttc agcccaacaa gtcttgttaa atatgaccat ccaaaaagtt
    15181 tttgaaaaac aatatggctc agagcttgat gataaagagg ttgatgatac tattgccgaa
    15241 gaaaaaaaac aatatggcga aaactaccaa cgtgtcttgt cacaagcagg tatgactctt
    15301 gaaacacgta aagctcaaat tcgtacaagt aaattagttg agttggcagt taagaaggta
    15361 gcagaagctg aattgacaga tgaagcctat aagaaagcct ttgatgagta cactccagat
    15421 gtaacggctc aaatcatccg tcttaataat gaagataagg ccaaagaagt tctcgaaaaa
    15481 gccaaggcag aaggtgctga ttttgctcaa ttagccaaag ataattcaac tgatgaaaaa
    15541 acaaaagaaa atggtggaga aattaccttt gattctgctt caacagaagt acctgagcaa
    15601 gtcaaaaaag ccgctttcgc cttagatgtg gatggtgttt ctgatgtgat tacagcaact
    15661 ggcacacaag cctacagtag ccaatattac attgtaaaac tcactaagaa aacagaaaaa
    15721 tcatctaata ttgatgacta caaagaaaaa ttaaaaactg ttatcttgac tcaaaaacaa
    15781 aatgattcaa catttgttca aagcattatc ggaaaagaat tgcaagcagc caatatcaag
    15841 gttaaggacc aagccttcca aaatatcttt acccaatata tcggtggtgg agattcaagc
    15901 tcaagcagta gtacatcaaa cgaatagtcc aaatcaatga gtcagggaaa aaactcgact
    15961 tcaggaaaaa atgaagcaaa cattcccaca ataaaacgca tagtacaagg tttgtactgc
    16021 cccccaaaaa agttagacaa ttaatttatc cgaaggattt agttctgtat tgcacagagc
    16081 taagtccttt tagttttatc ttaattctct tattgttgta ataatcaata tagtctataa
    16141 tggctcgttc caattgatta agtgatttaa atgtttgctc atagccataa aacatttcgg
    16201 attttaaaat gccaaagaaa gattccatcc taccgttgtc ttggctgttt cctttgcgtg
    16261 acatagatgc ttgaattccc ttactctcta ggaagcgatg ataagaatcg tgttgatatt
    16321 gccagccttg gtcactatgg agaatcgtat tctcgtagtg cttctctttg aatgcctgtt
    16381 ccaacattaa cgatcaatca atttaatcat gtacctaaga ttagaattgt ttatcccaaa
    16441 tttatttgaa agcttctcta agctatatcc ttgttttcta agttcataga tctgaacttt
    16501 atcatcataa gttaatttca taataaaaac accccaaaag ttagattttt tctgtctaac
    16561 ttttggggtg tagttcatgt acacctgata tgatgcgttt tataatttta aagacttttt
    16621 gaccagcctc atttttttaa cttgatactc agtgaaaagc aaagattaaa ctaggaagct
    16681 agctgtaggc tgctcaaaga acagctttga ggttgtagat aaaacttgtg aggtcaccaa
    16741 catatataat gtgaagctga cgtggtttga atagatttta gaagagtatg agtctggaag
    16801 ttttaatgga taatgcaaga ttccatagaa tgggtaagct agagttctta tgtgaagagt
    16861 ttgggcataa acttttacct tttcctccct actcatctta gtatagaaaa gtgaatctga
    16921 aatagtacat aactgcttct aaaacattct tataaattga tttaaattct caaatcatat
    16981 tattcagttc ttatttcatt ttgttctaca atcctgttga gaagacacgt gttcatatca
    17041 aaaaggtatt ggcaagttgc aatacctttt tacgaggctc tgttgtctta tttttgtttc
    17101 aactgactat atctcctatg gttctagttc agaaggctag gctataatta tgattgataa
    17161 gaagtatcat tccaagtatt gggagtgaat gtttcaaaat catgggtttc tataatggtc
    17221 aggctggcat ttgctagacc gccatcttta cgaagaagtg gttctttata gcctaggaga
    17281 gtacgaagac tggcagtaag attggcgccg tgtccgacaa ttagaatacg ttcagctgga
    17341 ctatctttta atgatttgat aaattggatg gtccgttgag ttgtactata gagggattcg
    17401 gctccgaaca ttcgagtgtc aaattgagca agatttgaac gaaaagcctg gatttgttgc
    17461 gggtaaatag cttccaaggt tgcaattttc aaaccttcta acttcccaag ttgccattca
    17521 cggagattag gaacgatttc taaagaacag ggggtataga gttgactttg gataatctca
    17581 gcagatttga ccgctcgagg taaatcactt gaataaatct gatcaaaagg aatttccttg
    17641 agatactgac caagtcgttt tagggtttca atggattcag gaagaagagg agaatcacca
    17701 ctagcacctt gaaaacgacc ttcttggttc cagagggtac gaccgtggcg gacaaagtag
    17761 agtttcatta cttgatgtcc tccaaaatat ctacaaagtc tgcctttaca aagctagcca
    17821 agtcttgtgg cgcgacgata atgctgtgtc cgacttcgcc tgcagagaca atcatttgat
    17881 ccaaatctag agcaatttta tcgataaaaa tgggataatt gtgtttctga cgaattccga
    17941 caggattatt ggctccatga atgtaaccag ttgttttttc taagtccttt tgtagaatca
    18001 tgctcacttt tttattgcca gaaattttag ctagtttctt ttcagacaag tgctgagtga
    18061 tagggacaat tccgataatc ggtccggtct tgtctcccaa aagcgccaag gttttgaaaa
    18121 tctgatctcg ttcataacct tgaggaagct ctccttctag ggcattgatt tgaatcccct
    18181 gatgagggat agctgcttta gataggattt gttccaccaa tgtttttttg attttaactt
    18241 tttttgccat tatttatatt tatcctccaa ttgactcatc caaataccaa gccagattcc
    18301 cagcgcaaag aagaaggcga tgatgacata accgacaagt gaaagtcctg tgtattggat
    18361 actttcagcg tttcctgcat ttggaattaa gatcaaaagg gtacttgata ggacgatacc
    18421 gatgatgaaa tgatagacac gtgagtggta gttgtttaag gcataatcca tcaattttga
    18481 aaaaacgatg agagttgcac ctgcaccaat tccaatcgga aagaaggttc ccaagaaatc
    18541 aaaagtttta aaaccagtca acataggagc atagagtccc aaaatcaaaa gtaaatttga
    18601 tgggctgagg ccaggaacca agacgccaag ggccaatagt gcgcctgcta ggacgaagtt
    18661 aagaaagctg gcgcttaagg ttccaacgac aaaatttaag gcatagagtc ctaatccaga
    18721 aatgataaag gttgtccata accaagctaa atcaatcttg tctcggtcag attctcgagt
    18781 tgattctttg aggaggctag gaactgtacc gataatagct cccgcaaagc tccataatac
    18841 aaaaacctga taattttcaa gcaggtattc aatcgggtag gaaaataagc cgattcccag
    18901 aagcataccg atggcaactg gaataaagta caaaacattt tctttaaagt ctttaaaggg
    18961 atgggccaga aagccaatca ttcgttcata gattcctaag attgctgcta gaacccctcc
    19021 ggaaattccc ggtaggataa atccaagagc aattacaatc cctttaataa cgcgtgctaa
    19081 ccatgagagc atatatttcc tccaactatt tctatttcaa aaaatcctta ctatattgta
    19141 tcacaatcag acacaaaaag aaaaagcaaa tgataaacaa atgcttttaa ggttttaaaa
    19201 aaagttttcg aaaggtttct tctttatttt ttaagggaga gataacgttg atatctaaat
    19261 cgtggtcaaa gccggcaatt tttcctttag atgtgtattg gtgaatatca taatctaaat
    19321 cagttttagg actgctctcc aaaaatcctg agtctgagcc gtaggacgga atccaaacag
    19381 aggtaaactt gcctgtatca atactgtgtt cttccatgaa gtagacacca acgtagatgc
    19441 cgatgttttt agcacctagt gatgctagtt ttgctcgaaa gttttcgaca ccttcgttca
    19501 tattagacat ggttttgtct tccacgtcaa gccaatagta actagggctg taaggagagg
    19561 cagcattgta gaaaacttcg gcagcctttt ccatttcttg gacacttttt ccagctacat
    19621 aagcgtagac agcaactggg acattccgct tttgaagttc agtgatatga ctcttatagg
    19681 ccttgtctat tccattgata aatgaagcat cattttcttt tgttgtttga gcaccactgt
    19741 gaacacgaac aatagcacct gaaatatttt gtgagagggc atcgtagttg atttcctcag
    19801 gacgctgcca gccagagagg tcaataatcg gtttgtctaa gtgtttcaaa gcctgtgctt
    19861 caatctgtgc tatattggat tttgttttaa acgattggct gtcattaagt gggcgattga
    19921 tgattaaaat gaacatcata atcccaaaaa aactaaataa aataagtgga tgaatttgtt
    19981 ttctcatatc ttataattct accctaaaaa tcaaaaaaaa tcaaaaaaat gggttaagga
    20041 agagacttta gagcattttt tcattcaaga gtgcggaatg atttgaaata tggtataata
    20101 aaagggaatt tctacagaaa agagaagatt atgtcaaatt ttgccattat tttagcagcg
    20161 ggtaaaggga ctcgcatgaa atctgatttg ccaaaagttt tgcacaaggt tgcgggtatt
    20221 tctatgttgg aacatgtttt ccgtagtgtg ggagctatcc aacctgaaaa gacagtaaca
    20281 gttgtaggac acaaggcaga attggttgag gaggtcttgg ctgaacagac agaatttgtg
    20341 actcaatctg aacagttggg aactggtcat gcagttatga tgacagagcc tatcttagaa
    20401 ggtttgtcag gacacacctt ggtcattgca ggagatactc ctttaatcac tggtgaaagc
    20461 ttgaaaaact tgattgattt ccatatcaat cataaaaatg tggccactat cttgactgct
    20521 gaaacggata atccttttgg ctatggacga attgttcgta atgacaacgc tgaggttctt
    20581 cgtattgttg agcagaagga tgctacagat tttgaaaagc aaatcaagga aatcaacact
    20641 ggaacatacg tctttgacaa cgagcgtttg tttgaggctt tgaaaaatat caataccaat
    20701 aacgctcaag gcgaatacta tattacagac gtcattggta ttttccgtga aactggtgaa
    20761 aaagttggcg cttatacttt gaaagatttt gatgaaagtc ttggggtaaa tgaccgtgtg
    20821 gcgcttgcga cagctgagtc agttatgcgt cgtcgcatca atcataaaca catggtcaac
    20881 ggtgttagct ttgtcaatcc agaagcaact tatatcgata ttgatgttga gattgctccg
    20941 gaagttcaaa tcgaagccaa tgttatcttg aaagggcaaa cgaaaattgg tgctgagact
    21001 gttttgacaa acggtactta tgtagtggac agcactatcg gagcaggagc ggtcattacc
    21061 aattctatga ttgaggaaag tagtgttgca gacggtgtga cagtcggtcc ttatgctcac
    21121 attcgtccaa attcaagtct gggtgcccaa gttcatattg gtaactttgt tgaggtgaaa
    21181 ggatcttcaa tcggtgagaa taccaaggct ggtcatttga cttatatcgg aaactgtgaa
    21241 gtgggaagca acgttaattt cggtgctgga actattacag tcaactatga cggcaaaaac
    21301 aaatacaaga cagtcattgg agacaatgtc tttgttggtt caaattcaac cattattgca
    21361 ccagtagaac ttggtgacaa ttccctcgtt ggtgctggtt caactattac taaagacgtg
    21421 ccagcagatg ctattgctat tggtcgcggt cgtcagatca ataaagacga atatgcaaca
    21481 cgtcttcctc atcatcctaa gaaccagtag gagcctatca tggagtttga agaaaaaacg
    21541 cttagccgaa aagaaatcta tcaaggacca atatttaaac tggtccaaga tcaggttgaa
    21601 ttaccagaag gcaagggaac tgcccgacgg gatttgattt tccacaatgg ggctgtctgt
    21661 gttttagcag taacggatga acaaaaactt atcttggtca agcagtaccg caaagctatc
    21721 gaggctgtct cttacgaaat tccagccgga aaattggaag taggagaaaa cacagcccct
    21781 gtggcagctg cccttcgtga attagaggaa gaaacagcct atacagggaa attagaactc
    21841 ttgtacgatt tttattcagc tattggcttt tgtaatgaga agttaaaact atatttagca
    21901 agcgatttga caaaagtgga aaatccgcgt ccgcaggatg aggatgaaac cttggaagtc
    21961 cttgaagtga gcttagaaga agcgaaagaa ttaatccaat caggtcatat ctgtgatgcc
    22021 aagacaatta tggctgttca gtattgggag ttgcagaaaa aatagaggag gtcagtatgg
    22081 gtaaatcttt attaacggat gaaatgattg aaagagctaa tagaggcgaa aaaatttcag
    22141 gtcctccttt gctagatgat aatgaggaaa ctaagatttt accaacctct tcttcccgtt
    22201 ttggttatgc caatcctaag gatcatggtt ttagccagga aaccttgaag attcaggtcg
    22261 aaccatctat tcataaaagc cgtcgtattg aaaataccaa gagaaatgtc ttcaattcta
    22321 agttgaataa aatcttattt gcggtcatct ttctcttgat tttgcttgtt ttagcaatga
    22381 aacttttgta atagaaaagg aattgaaatg aaaataggaa ttattgctgc tatgccagaa
    22441 gaactggctt atctggtcca gcatttagat aatacccagg agcaagttgt tttggggaat
    22501 acctatcata caggaaccat tgcttctcat gaagtcgttc ttgtagaaag tggaattggt
    22561 aaggtcatgt ctgctatgag tgtggcgatt ttggctgatc atttccaggt ggatgccctt
    22621 attaatacgg gttcagctgg ggcagtagca gaaggtatcg ctgttgggga tgtcgtgatt
    22681 gctgacaaat tagcctatca tgacgtagat gtcacagctt ttggctatgc ttatggacaa
    22741 atggcgcaac aaccgcttta tttcgaatca gacaaaacct ttgttgctca aatccaagag
    22801 agtttatctc aattggacca aaactggcat cttggtttga ttgctacagg agatagtttt
    22861 gttgcaggaa atgacaagat agaagcgatt aagtcccatt tcccagaagt tttagccgtg
    22921 gagatggagg gggcagctat tgctcaagca gcgcataccc tcaatctccc agtcttagtc
    22981 atccgagcta tgagtgacaa tgccaaccat gaagcaaaca tcttttttga tgagtttatt
    23041 atcgaagctg gacgtcgctc tgcccaagtc ttgttggcct ttttgaaggc tttagattaa
    23101 gcggaaattt gacagttttt ctagcttatg ataagattta agtaaagaaa agctagaaaa
    23161 cgtttcagag gatattatga gtattgaaat gaccgtcagt gagattgcag aggtcttagg
    23221 attatctcgc caagcaatca ataaccgtgt caaagaatta ccagaagaag acacagataa
    23281 aaatgacaaa ggggtaacag ttgttaccag aagtggcttg attaagctag aagaaatcta
    23341 taaaaaaacg atttttgaag atgaacctgt cagtgaagat gtcaaacaac gtgaactgat
    23401 ggagattcta gtggatgaga agaatgcaga aattcttcgt ctttatgaac aattaaaagc
    23461 caaggatcgt cagttatcag aaaaagacga gcagatgcgt atcaaagacc gtcagattgc
    23521 tgagaaagac aaacaattag atcagcaaca acaattgacc cttcaagcca tgaaggatca
    23581 agaaaatctt aagctagagc tggaccaagc aaaagaagaa gtccaatcca ctaaaaaagg
    23641 cttttttgct cgtttatttg gaggataatc aaggagctgt ttaggttaaa tgctaacctg
    23701 atggcttctt ttgtttgtga atagtatagt tgattagaac agagacagta gaggagaggt
    23761 acagaatgga acgattagaa gattacattg cttttgattt agaatttaat cagcacgaag
    23821 gacaaacaca cttgattcaa gtatcggcag tgcgttttag agatggtcgg gaaatcgatg
    23881 cctatgattc ctatgttcat accagcgtcc ctctaaaaag ctttatcaat ggtttgaccg
    23941 ggattacagc tgagacctta aaagatgctc ctccagttga gaaagtctta gaagaattcc
    24001 aagagtttgt gggttctttg ctgatgatag gctacaatgc tgctaaaagt gatttaccta
    24061 ttttagcaga gcatggttta gactatagcc aacagtacaa ggtggatttg tatgatgaag
    24121 cttttgaacg tcggagttca gatttacatg gtattgccaa tctcaaattg caaactgttg
    24181 cctcatttct tggatttcaa ggtcagtctc ataatagttt agaggatgct cggatgacgg
    24241 cgcgtgttta cgaatccttc ttagagtcgg atcaagctag ggaattgtta gagacagaaa
    24301 gtagcttatc aaacaatcct tttggtggct tggacttgtc tcaattattt gactaggagt
    24361 gcctatgaaa cctgaaaaac ctaaaaaatt gggtcttaaa cagatttacc tcaatcttga
    24421 taaaatcctc tttctatttt tcttgatttt tatgatagtg gagtatttgt gggtaccatt
    24481 caattcatgg ttggctagct tcttattaga tcagacaggt tatcttttta tttcctataa
    24541 caatgtctta gccatcctta ctcattctcc attgattagt ctagcttttt tagccttgat
    24601 tgtaattaac cttctggttg cttattttca aataggactc ctctttattg gtgctcgtca
    24661 tctcctctat aatgaaaagc gaaggctaat tgagtatatc cgcaaggttt tccatgaaag
    24721 ttttggattt atgaaaaagc taacttgcgc taaagccttg tttatctttt tctatatagc
    24781 tatgctgttt ccttttatac ggaaaatgct gaagatttat tatcttaata aaatcgtcat
    24841 tccagagttt atccaagctt atttagaaga tagatattgg atgtggtggc tgagcatcct
    24901 acttctatct cttatctttc tctatgtctc tgtcagattg atgtttgccc ttccgaagat
    24961 tgtatatgat cagctgactg ttcgagaagc agtgatgttt agcttggaga aaaccaagaa
    25021 gagagttact ttttatgctt ggaatttatt ttacatcttg ctcaaagcac atttattatt
    25081 ttatcttcct ttgatccctt tattattggc tcaaactttg gtagatgata tcactcagag
    25141 agagtctctg attcttggta ttttgaattt tgtcgtgatt aaaaatctct attatatggc
    25201 tctgacttat tttttggtta aatttgtttc atttttgaca ggaaaggagc tggatatgct
    25261 tcctaggaga gaaaaagatc acatcgtgcg atggggtgtc atgacttgtg ccagtctttt
    25321 ctttgcctta gaaggttata tttatctgga ggctcccatg gttcatctac ctcaacttat
    25381 ttctcaccga ggggtttcca atgcaaatgg gattcaaaat acagtagagt ccttggaaac
    25441 tacagcacaa ctcaaaccag acttggtgga gacggatgtg caggaaacaa aagatgggca
    25501 gtttgtcatg atgcatgatg ctaacttgaa aaatctagca ggtatcaata aaagtcctca
    25561 agacttaaac ttggaggagc ttaaagggat tgatattttt gaaaatggct accagactaa
    25621 aatttcaagc tttgaagatt atctcagtcg agccaacgaa cttggtcaaa aattactaat
    25681 tgaaattaaa accagtaaaa aagatagtcc agacatgatg aaccgctttt tagcccgtta
    25741 tgctgcaaag ctcaagattt atggacatca aatccagtct ttagactacc atgttgtcga
    25801 aaaagtaaga cagtatgatg ccgaactgcc agtttatttc atcatgccct acaattctgt
    25861 ctttcctaaa acaagagcga caggatatac tatggagtac tcaaccttgg atgaatattt
    25921 tgtaagcaaa ctatggacaa cggatcagaa actttatgtc tggactgtca atgattcaga
    25981 agctatcagc aaatctcttc acttaggagt agatggagtg attacagatg atttggaaaa
    26041 agttcagcgg gaaatagaag tagcccaaga agacccagaa tatacggatt tgctcttgaa
    26101 aaaagcattg gaattctttg aattttagta ataaaaaaga ggaacggttg ttcctcccat
    26161 gataggtaag tattcttgtg aatgcttgct tttttgtggt tgcaatccgt ttacgagaat
    26221 tgtttgtatt gttcttgttt caatttactt tatagtgctt tgaagttgga atgctacact
    26281 ataacttcta aaatatagtg aaatgaacca aaaatagtac acaatgtggt ataatcttct
    26341 tatggcatat tcaatagatt ttcgtaaaaa agttctctct tattgt
//
LOCUS       DBERPV010000026        25982 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.26, whole genome shotgun sequence.
ACCESSION   DBERPV010000026 DBERPV010000000
VERSION     DBERPV010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 25982)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25982)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25982
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.26"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            283..6699
                     /locus_tag="ACL8C7_001423"
     CDS             283..6699
                     /locus_tag="ACL8C7_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HGS1395603.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     AENKEKHEDIHSAMETSKDTEEKKATVIEEKEVVSKNPVIDTKTSNEEARIKEDSNQS
                     QGDNAHSSANKGTENPKKEDRLVYIAEFKDKESGEKAIKELSSLKNTKVLYTYDRIFN
                     GSAIETTPDNLDKIKQIEGISSIERAQKVQPMMNHARKEIGVEEAIDYLKSINAPFGK
                     NFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKIPHAFN
                     YYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQIFSYK
                     MYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRALRKAGI
                     PMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQTVEFDK
                     VNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDLRGKIA
                     VMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGTKSQVF
                     SISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVGDEKEI
                     DFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVINGKSTY
                     GYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQNTARP
                     MMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGSISLKE
                     IKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGKQIVPE
                     IHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESVEEMEA
                     LNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGKPKIPG
                     TLNKGIGGEHGIDKFNPAGVIQNRKDKNRTSLDQDPDLFAFNNQGVHAESTSGSKIAN
                     IYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQKDLKVVSREHFI
                     RGILNSKGNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATKIRGQF
                     EPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLITKDTYH
                     KVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYAGEGQG
                     RNRKLDKDGNTIYEISGAGDLRGKIIEVIALDGASNFTKIHRIKFANQADEKGMISYY
                     LVDPDQDSSKYQKLGEIPESKFKNLKNVKDDSLNKETAEVENNLLVDNQSIEGKSLFN
                     IHKTISTIRDFENKDLKKLIKKKYKQEDDFVNGGTRTVERDYKYDDKGNIIAYDDGTD
                     LEYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKSIEIKATKY
                     DFHSKTMTFDLYANINDIVDGLAFAGDMRLFVKDNDQKKAEIKIRMPEKIKETKAEYP
                     YVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGYALKVT
                     TYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRALSETTIYADSRNVEDGRSTQSVLMS
                     ALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKFNVEAI
                     KEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWELRVNE
                     SVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGNVYLQ
                     TGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRNNGFDG
                     EIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTGEVSEL
                     KPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKDAGYVI
                     NLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQREDHS
                     QKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVGIFLGL
                     KKKNQD"
     gene            7324..7800
                     /locus_tag="ACL8C7_001424"
     CDS             7324..7800
                     /locus_tag="ACL8C7_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGS1395604.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVCLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEALYAYIAEAIA"
     gene            7838..8143
                     /locus_tag="ACL8C7_001425"
     CDS             7838..8143
                     /locus_tag="ACL8C7_001425"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS1395605.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            8191..9666
                     /locus_tag="ACL8C7_001426"
     CDS             8191..9666
                     /locus_tag="ACL8C7_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HGS1395606.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLLIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVAFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            9971..16672
                     /gene="bgaA"
                     /locus_tag="ACL8C7_001427"
     CDS             9971..16672
                     /gene="bgaA"
                     /locus_tag="ACL8C7_001427"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000515226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored adhesin/beta-galactosidase BgaA"
                     /protein_id="HGS1395607.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNIVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASNQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKIF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVEEYEVDKWEIAEEDKAKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPAVPTV
                     TVGGEAVTGLTSQKPMQYRTLAYGAKLPEVTASAKNAAVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLLVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVDLTIQANTEKKIAQSIRP
                     VNVVTDLHQEPTLPSTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARARVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRIEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAKLKAGEMNHF
                     SFDKVETYAIRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLSVEWEEVPAEN
                     LTKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIEAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSASSQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(16920..17366)
                     /locus_tag="ACL8C7_001428"
     CDS             complement(16920..17366)
                     /locus_tag="ACL8C7_001428"
                     /inference="COORDINATES: protein motif:HMM:NF013752.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS1395608.1"
                     /translation="MFDKEQKRGYKQSAKNLANWHYNDKEDSYTHPDGWYYRFHHTKY
                     QKTQTDFQQEIKVYYADEPESAPQKGLYMNERYQNLKAKECQALLSPQGRQIFAQRKI
                     DVEPVFGQIKASLGYKRCNLRGKRQVRIDMGLVLMANNLLKHSEMK"
     gene            complement(17531..17776)
                     /locus_tag="ACL8C7_001429"
     CDS             complement(17531..17776)
                     /locus_tag="ACL8C7_001429"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS1395609.1"
                     /translation="MHIHYNTNQTTLPLEISSFLPQDHLVFTIEKVVNTLEERHFYTS
                     YHAFDRPSYHPKMLVSTLLFAYSQGIFSGRKIEKWKS"
     gene            complement(17986..18345)
                     /locus_tag="ACL8C7_001430"
     CDS             complement(17986..18345)
                     /locus_tag="ACL8C7_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HGS1395610.1"
                     /translation="MGMILMKLASILLLILTLVICIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            18456..19403
                     /locus_tag="ACL8C7_001431"
                     /pseudo
     CDS             18456..19403
                     /locus_tag="ACL8C7_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241739.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            19387..19944
                     /locus_tag="ACL8C7_001432"
     CDS             19387..19944
                     /locus_tag="ACL8C7_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGS1395611.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQADLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            19937..20191
                     /locus_tag="ACL8C7_001433"
     CDS             19937..20191
                     /locus_tag="ACL8C7_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395612.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            20203..22257
                     /locus_tag="ACL8C7_001434"
     CDS             20203..22257
                     /locus_tag="ACL8C7_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HGS1395613.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            22436..23296
                     /locus_tag="ACL8C7_001435"
     CDS             22436..23296
                     /locus_tag="ACL8C7_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HGS1395614.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            23507..24217
                     /gene="ccdA2"
                     /locus_tag="ACL8C7_001436"
     CDS             23507..24217
                     /gene="ccdA2"
                     /locus_tag="ACL8C7_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HGS1395615.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            24237..24803
                     /locus_tag="ACL8C7_001437"
     CDS             24237..24803
                     /locus_tag="ACL8C7_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HGS1395616.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            24814..25926
                     /gene="msrB"
                     /locus_tag="ACL8C7_001438"
     CDS             24814..25926
                     /gene="msrB"
                     /locus_tag="ACL8C7_001438"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HGS1395617.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
BASE COUNT         8482 a         4563 c         5494 g         7443 t
ORIGIN      
        1 tgttttgagc aacctgcggc tagtttccta gtttgctctt tgattttcat tgagtactaa
       61 tcttattttt taatgtgtgc taaaaaataa attaatgcat gttaattttt cttgaattaa
      121 atttttttaa atgatatact gtatttatgg agagataaca attatatata aatgtactac
      181 tctatttcct agataatact tagtaaaact ttttataaca aaggctagca aagttaaagt
      241 ttattatcta ttggaagtta tataaatatg taaggaatta aaatgaaaaa aagtacagta
      301 ttgtcattaa ccacagctgc agttatttta gcagcctatg cccctaatga ggtagtctta
      361 gcagacacat ctagctctga agatgcttta agcatctctg ataaagaaaa agtagcagaa
      421 aataaagaga aacatgaaga tatccatagt gctatggaaa cttcaaagga tactgaagaa
      481 aagaaagcaa cagttattga ggaaaaagaa gttgttagta aaaatcctgt gatagacact
      541 aaaactagca atgaagaagc aagaatcaaa gaagattcca atcaatccca aggagataat
      601 gcacactcgt ctgcaaataa aggcacagaa aatcccaaaa aagaagatag acttgtctat
      661 attgctgaat ttaaagataa agaatctgga gaaaaagcaa tcaaggaact atccagtctt
      721 aagaatacaa aagttttata tacttatgat agaattttta acggtagtgc catagaaaca
      781 actccagata acttggacaa aattaaacaa atagaaggta tttcatcgat tgaaagggca
      841 caaaaagtcc aacccatgat gaatcatgcc agaaaggaaa ttggagttga ggaagctatt
      901 gattacctaa agtctatcaa tgctccgttt gggaaaaatt ttgatggtag aggtatggtc
      961 atttcaaata tcgatactgg aacagattat agacataagg ctatgagaat cgatgatgat
     1021 gccaaagcct caatgagatt taaaaaagaa gacttaaaag gcactgataa aaattattgg
     1081 ttgagtgata aaatccctca tgcgttcaat tattataatg gtggcaaaat cactgtagaa
     1141 aaatatgatg atggaaggga ttattttgac ccacatggga tgcatattgc agggattctt
     1201 gctggaaatg atactgaaca agacatcaaa aactttaacg gcatagatgg aattgcacct
     1261 aatgcacaaa ttttctctta caaaatgtat tctgacgcag gatctgggtt tgcgggtgat
     1321 gaaacaatgt ttcatgctat tgaagattct atcaaacaca acgttgatgt tgtttcggta
     1381 tcatctggtt ttacaggaac aggtcttgta ggtgagaaat attggcaagc tattcgggca
     1441 ttaagaaaag caggcattcc aatggttgtc gctacgggta actatgcgac ttctgcttca
     1501 agttcttcat gggatttagt agcaaataat catctgaaaa tgaccgacac tggaaatgta
     1561 acacgaactg cagcacatga agatgcgata gcggtcgctt ctgctaaaaa tcaaacagtt
     1621 gagtttgata aagttaacat aggtggagaa agttttaaat acagaaatat aggggccttt
     1681 ttcgataaga ataaaatcac aacaaatgaa gatggaacaa aagctcctag taaattaaaa
     1741 tttgtatata taggcaaggg acaagaccaa gatttgatag gtttggatct taggggcaaa
     1801 attgcagtaa tggatagaat ttatacaaag gatttaaaaa atgcttttaa aaaagctatg
     1861 gataagggtg cacgcgccat tatggttgta aatactgtaa attactacaa tagagataat
     1921 tggacagagc ttccagctat gggatatgaa gcggatgaag gtactaaaag tcaagtgttt
     1981 tcaatttcag gagatgatgg tgtaaagcta tggaacatga ttaatcctaa taaaaaaact
     2041 gaagtcaaaa gaaataataa agaagatttt aaagataaat tggagcaata ctatccaatt
     2101 gatatggaaa gttttaattc caacaaaccg aatgtaggtg acgaaaaaga gattgacttt
     2161 aagtttgcac ctgacacaga caaagaactc tataaagaag atatcatcgt tccagcagga
     2221 tctacatctt gggggccaag aatagattta cttttaaaac ccgatgtttc agcacctggt
     2281 aaaaatatta aatccacgct taatgttatt aatggcaaat caacttatgg ctatatgtca
     2341 ggaactagta tggcgactcc aatcgtggca gcttctactg ttttgattag accgaaatta
     2401 aaggaaatgc ttgaaagacc tgtattgaaa aatcttaagg gagatgacaa aatagacctt
     2461 acaagtctta caaaaattgc cctacaaaat actgcgcgac ctatgatgga tgcaacttct
     2521 tggaaagaaa aaagtcaata ctttgcatca cctagacaac agggagcagg cctaattaat
     2581 gtggccaatg ctttgagaaa tgaagttgta gcaactttca aaaacactga ttctaaaggt
     2641 ttggtaaact catatggttc catttctctt aaagaaataa aaggtgataa aaaatacttt
     2701 acaatcaagc ttcacaatac atcaaacaga cctttgactt ttaaagtttc agcatcagcg
     2761 ataactacag attctttaac tgacagatta aaacttgatg aaacatataa agatgaaaaa
     2821 tctccagatg gtaagcaaat tgttccagaa attcacccag aaaaagtcaa aggagcaaat
     2881 atcacatttg agcatgatac tttcactata ggcgcaaatt ctagctttga tttgaatgcg
     2941 gttataaatg ttggagaggc caaaaacaaa aataaatttg tagaatcatt tattcatttt
     3001 gagtcagtgg aagaaatgga agctctaaac tccaacggga agaaaataaa cttccaacct
     3061 tctttgtcga tgcctctaat gggatttgct gggaattgga accacgaacc aatccttgat
     3121 aaatgggctt gggaagaagg gtcaagatca aaaacactgg gaggttatga tgatgatggt
     3181 aaaccgaaaa ttccaggaac cttaaataag ggaattggtg gagaacatgg tatagataaa
     3241 tttaatccag caggagttat acaaaataga aaagataaaa atagaacatc tctagatcaa
     3301 gatccagact tatttgcctt taacaaccaa ggtgttcatg cagaatccac tagtggttct
     3361 aagattgcta acatttatcc tttagattca aatggaaatc ctcaagatgc tcaactagaa
     3421 agaggactaa ctccatctcc acttgttcta agaagtgcag aagaaggact aatttcaatt
     3481 gtaaacacca acaaagaagg agaaaaccaa aaagacctta aagttgtatc aagagagcac
     3541 ttcataagag gaattctaaa ttctaaggga aatgacgcta agggtatcaa atcatccaaa
     3601 ctaaaagttt ggggtgactt gaaatgggat ggactcatct ataacccaag aggtagagaa
     3661 gaaaatgccc cagaaagtaa ggataaccaa gatccagcta ctaagatacg aggacaattt
     3721 gaaccgattg cggaaggtca atatttctat aaatttaaat atagattaac taaagattac
     3781 ccatggcagg tttcctatat tcctgtaaaa attgataaca cagcccctaa gattgtttcg
     3841 gttgattttt caaatcctga aaaaattaag ctaatcacaa aggatactta tcacaaggta
     3901 aaagatcaat acaagaatga aactttattt gctagagatc aaaaagaaca tcctgaaaaa
     3961 tttgatgaga ttgcaaatga ggtgtggtat gcaggagctg ctcttgttaa tgaagatgga
     4021 gaggttgaga aaaatcttga agtaacttat gcaggtgagg gtcaaggaag aaataggaag
     4081 cttgataaag atgggaatac tatctatgaa attagcggag caggagatct aagaggaaaa
     4141 atcatcgaag taatcgccct agatggagca agcaacttta ccaaaatcca taggattaaa
     4201 tttgctaatc aagctgatga aaaagggatg atttcctatt atctagtaga tcctgatcag
     4261 gattcatcta aataccaaaa gcttggcgaa attcctgaat ctaaatttaa gaatttaaaa
     4321 aatgttaaag atgatagcct aaacaaagag acagctgagg tggaaaataa ccttttagta
     4381 gataatcagt ctatcgaagg aaaatctctc tttaatattc ataaaactat ttcaacaatt
     4441 agagactttg aaaataaaga cctaaagaaa ctcattaaaa agaaatataa gcaagaagac
     4501 gactttgtaa atggtggaac aagaacagta gagcgtgatt ataaatacga tgataaagga
     4561 aatataatag cctacgatga tgggactgat ctagaatatg aaactgagaa acttgacgaa
     4621 atcaaatcaa aaatttatgg tgttctaagt ccgtctaaag atggacactt tgaaattctt
     4681 ggaaagataa gtaatgtttc taaaaatgcc aaggtatatt atgggaataa ctataaatct
     4741 atagaaatca aagcgaccaa gtatgatttc cactcaaaaa cgatgacatt tgatctatac
     4801 gctaatatta atgatattgt ggatggatta gcttttgcag gagatatgag attatttgtt
     4861 aaagataatg atcagaaaaa agctgaaatt aaaattagaa tgcctgaaaa aattaaggaa
     4921 actaaagcag aatatcccta tgtatcaagt tatgggaatg tcatagaatt aggggaagga
     4981 gatctttcaa aaaacaaacc agacaattta actaaaatgg aatctggtaa aatctattct
     5041 gattcagaaa aacaacaata tctgttaaag gataatatca ttctaagaaa aggctatgca
     5101 ctaaaagtga ctacctataa tcctggaaaa acggatatgt tagaaggaaa tggagtctat
     5161 agcaaggaag atatagcaaa aatacaaaag gccaatccta atctaagagc cctttcagaa
     5221 acaacaattt atgctgatag tagaaatgtt gaagatggaa gaagtaccca atctgtatta
     5281 atgtcggctt tggacggctt taacattata aggtatcaag tgtttacatt taaaatgaac
     5341 gataaagggg aagctatcga taaagacgga aatcttgtga cagattcttc taaacttgta
     5401 ttatttggta aggatgataa agaatacact ggagaggata agttcaatgt agaagctata
     5461 aaagaagatg gctccatgtt atttattgat accaaaccag taaacctttc aatggataag
     5521 aactacttta atccatctaa atctaataaa atttatgtac gaaatccaga attttattta
     5581 agaggtaaga tttctgataa gggtggtttt aactgggaat tgagagttaa tgaatcggtt
     5641 gtagataatt atttaatcta cggagattta cacattgata acactagaga ttttaatatt
     5701 aagctgaatg ttaaagacgg tgacatcatg gactggggaa tgaaagacta taaagcaaac
     5761 ggatttccag ataaggtaac agatatggat ggaaatgttt atcttcaaac tggctatagc
     5821 gatttgaatg ctaaagcagt tggagtccac tatcagtttt tatatgataa tgttaaaccc
     5881 gaagtaaaca ttgatcctaa gggaaatact agtatcgaat atgctgatgg aaaatctgta
     5941 gtctttaaca tcaatgataa aagaaataat ggattcgatg gtgagattca agaacaacat
     6001 atttatgtaa atggaaaaga atatacatca tttgatgata ttaaacaaat aacagacaag
     6061 acactaaaca ttaagattgt tgtaaaagat tttgcaagaa atacaaccgt aaaagaattc
     6121 attttaaata aagatacggg agaggtaagt gaattaaaac ctcatagggt aactgtgacc
     6181 attcaaaatg gaaaagaaat gagttcaacg atagtgtcgg aagaagattt tattttacct
     6241 gtttataagg gtgaattaga aaaaggatac caatttgatg gttgggaaat ttctggtttc
     6301 gaaggtaaaa aagacgctgg ctatgttatt aatctatcaa aagatacctt tataaaacct
     6361 gtattcaaga aaatagagga gaaaaaggag gaagaaaata aacctacttt tgatgtatcg
     6421 aaaaagaaag ataacccaca agtaaaccat agtcaattaa atgaaagtca cagaaaagag
     6481 gatttacaaa gagaagatca ttcacaaaaa tctgattcaa ctaaggatgt tacagctaca
     6541 gttcttgata aaaacaatat cagtagtaaa tcaactacta acaatcctaa taagttgcca
     6601 aaaactggaa cagcaagcgg agcccagaca ctattagctg ccggaataat gtttatagta
     6661 ggaatttttc ttggattgaa gaaaaaaaat caagattaag acaaaagcta tagaaaaaat
     6721 ggtttatgta ctgagattag atagtgaggt gatgacatag ttttgtgaaa acagccattt
     6781 ataactcaat tatttagttt acttcactat tgatactatt tggagttatt aatggactta
     6841 gtttagataa ctaatgaatt gattgaaagg gttagtattg acaatattgg tcatattgat
     6901 tagaaaatag agtctatcaa aatttaaagg ctaatagagg tgatgagaca atttcaagga
     6961 attaagtagc gtttggttgc ttaattcctt tttatttgga aggaagtttt tcgtaaccgc
     7021 ccaataacga agtctattgg acggttacga tatgatcact gacttcgtca gtcttatcta
     7081 caacctcaaa actgtgtttt gagcaacctg cggctagctt cctagtttac tctttgattt
     7141 tcattgagta ttagaacaga aaaaatgctt ggagtatttg tttgtgtgtt tatttttaca
     7201 taacaaacta taaacaaaac aaaaatataa aaaaagagac aaaaaagaac agaaagtaat
     7261 tgacaacggt ttcatatagt gttatactta tggcataaag ttaatggaaa gaagggaaaa
     7321 cttatggtat tagattattt ctttgacaaa aaccttgtgt tttgcttaga agcggataat
     7381 caagaacaac tctttgatca ggttgcaact ttattggaag aacgagaaat tgtcactcca
     7441 acttatcgtg aagccttgat cacgcgtgaa aagtcatttc caactggttt agatatggaa
     7501 tttctaggaa aggacttgcc aaatgtagcg attcctcata cagatattgt tcataatcta
     7561 gctgagaaag tggtggttgt tcgattagag aaaccagtaa cttttcacaa tatgatagct
     7621 cctgataagg aagtagaagt atgcttactc ttctttatca tcaataattc aagttcaagt
     7681 caaacgaaca ttcttgctca gttgatggac ttcttcacag gaaatggtca tcttgaagac
     7741 ctatcaaaaa tttctgaacc agaagccctt tatgcttata tagctgaagc aatcgcttaa
     7801 tcttgtctat taaaaaataa aatcggagga aatccaaatg attaaaattc ttgctgcctg
     7861 cggtgcaggt gttaactcaa gtcaccaaat taaaagtgct ctagaagaag aactttcaaa
     7921 ccgtggttat gatgttcact gtgatgcagt catggtgaaa gatgtaaacg aagaccttat
     7981 gaaaggttac gatatcttta caccaatcgc tgcaacagat cttggttttg aaccaggtat
     8041 cccagttatc gaagctgggc caatcttatt ccgtatacca gcaatgagcg ctccagtatt
     8101 tgacaatatt gaagcagcta ttaaagaaca cggattaagc taattctaat ttgttaacat
     8161 tcatataaca taaaaaaggg aggaactgtt atggatgcaa tctttgacct aatcggaaag
     8221 gttttcaatc ccatcttaga aatgggtgga cctgtcatta tgttaatcat tttgacagta
     8281 ttggctttac tttttggagt gaaattctcc aaagcgcttg aaggtggtat caaacttgcc
     8341 atcgctctta caggtatcgg tgctatcatc ggtatgctaa atggtgcttt ctcagcatca
     8401 cttgcaaaat tcgttgaaaa cactggtata caattgagta ttaccgacgt tggttgggca
     8461 ccactcgcaa caatcacttg gggttctgct tggacacttt acttcttgct catcatgttg
     8521 attgtcaacg tagtgatgct tgctatgaag aaaaccgata cacttgatgt cgatatcttt
     8581 gatatctggc acttgtctat cacaggtctc ttgattaaat ggtatgctga taacaatggt
     8641 gtgagtcaag gggtttcact cttgattgct acagcagcta tcgttcttgt cggtgtgttg
     8701 aaaattatca actctgactt gatgaaacct acatttgatg accttcttaa cgccccaagt
     8761 tcatcaccaa tgacatcaac tcacatgaac tacatgatga acccagttat catggttttg
     8821 gataagattt ttgaaaaatt cttcccaggc cttgataaat atgactttga tgctgctaaa
     8881 ttgaacaaga aaatcggttt ctggggatct aaattcttca tcggtttcat ccttggtatc
     8941 gttatcggta ttatgggaac tccacatcca attgcaggtg ttgcagatgc agataaatgg
     9001 cgtcttgtta tcaaaggatg gttgtctctt ggtttgactg ccggtgtatc tttggaactc
     9061 ttctcactta tcggttcatg gttcatcgca gccgtagaac cactatcaca aggtattaca
     9121 aacgttgcta ctaaacgtct tcaaggacgt aaattcaata tcggtcttga ctggccattc
     9181 atcgctggtc gtgctgaaat ctgggcttgt gccaacgtac ttgcaccaat catgttgatt
     9241 gaagcagtgc ttctttcaaa agttggaaat ggtatcttgc cacttgcagg tatcatcgct
     9301 atgggtgtta ctccagctct cttggttgta actcgtggta aattgctccg tatgattatc
     9361 ttcggaacac tcttgttgcc actcttcctt ctttcaggta cccttattgc accatttgca
     9421 acagaacttg ctaaaggtgt aggtgccttc ccagaaggtg tgagccaaac tcaattgatt
     9481 actcactcta ctcttgaagg accaatcgaa aaacttcttg gttggacaat tggtaacact
     9541 acaactggtg atatcaaagc aatccttggt gcagtagcct tccttgtatt ctatatcggt
     9601 atctttgctt ggtacagaaa acaaatgatc aaacgtaacg aagagtacgc agcaaaagca
     9661 aaataatgcg ctcctataaa atataaactc aatgaaaatc aaagagcaaa ctaggaagct
     9721 agccgcaggt tgctcaaaac acagttttga ggttgtagat aagactgact aagtcagctc
     9781 aaaacatggt tttgaggttg tagatgaaac tgacgaagtc agtaatcata tctacggcaa
     9841 ggcgacactg acgaagtttg aattggattt tcgcagagtg taaattgttg aaactaggtt
     9901 gtcataccat gtataccact tgggctttgg tagtagctaa ctgcactaaa tataatataa
     9961 ggagggtttt atggggaaag gccattggaa tcggaaaaga gtttatagca ttcgtaagtt
    10021 tgctgtggga gcttgctcag taatgattgg gacttgtgca gttctattag gaggaaatat
    10081 agctggagaa tctgtagttt atgcggatga aacacttatt actcatactg ctgagaaacc
    10141 taaagaggaa aaaatgatag tagaagaaaa ggctgataaa gctttggaaa ctaaaaatat
    10201 agttgaaagg acagaacaaa gtgaacctag ttcaactgag gctattgcat ctgagaagaa
    10261 agaagatgaa gccgtaactc caaaagagga aaaagtgtct gctaaaccgg aagaaaaagc
    10321 tccaaggata gaatcacaag cttcaaatca agaaaaaccg ctcaaggaag atgctaaagc
    10381 tgtaacaaat gaagaagtga atcaaatgat tgaagacagg aaagtggatt ttaatcaaaa
    10441 ttggtacttt aaactcaatg caaattctaa ggaagccatt aaacctgatg cagacgtatc
    10501 tacgtggaaa aaattagatt taccgtatga ctggagtatc tttaacgatt tcgatcatga
    10561 atctcctgca caaaatgaag gtggacagct caacggtggg gaagcttggt atcgcaagat
    10621 tttcaaacta gatgaaaaag acctcaagaa aaatgttcgc cttacttttg atggcgtcta
    10681 catggattct caagtttatg tcaatggtca gttagtgggg cattatccaa atggttataa
    10741 ccagttctca tacgatatca ccaaatacct tcacaaagat ggtcgtgaga atgtgattgc
    10801 tgtccatgca gtcaacaaac agccaagtag ccgttggtat tcaggaagtg gtatctatcg
    10861 tgatgtgact ttacaagtga cagataaggt gcatgttgag aaaaatggga caactatttt
    10921 aacaccaaaa cttgaagaac aacaacatgg caaggttgaa actcatgtga ccagcaaaat
    10981 cgtcaatacg gacgacaaag accatgaact tgtagccgaa tatcaaatcg ttgaacgagg
    11041 tggtcatgct gtaacaggct tagttcgtac agcgagtcgt accttaaaag cacatgaatc
    11101 aacaagccta gatgcgattt tagaagttga aagaccaaaa ctctggaccg ttttaaatga
    11161 caaacctgcc ttgtacgaat tgattacgcg tgtttaccgt gacggtcaat tggttgatgc
    11221 taagaaggat ttgtttggtt accgttacta tcactggact ccaaatgaag gtttctcttt
    11281 gaatggtgaa cgtattaaat tccatggagt atccttgcac cacgaccatg gggcgcttgg
    11341 agcagaagaa aactataaag cagaatatcg ccgtctcaaa caaatgaagg agatgggagt
    11401 taactccatc cgtacaaccc acaaccctgc tagtgagcaa accttgcaaa tcgcagcaga
    11461 actaggttta ctcgttcagg aagaggcctt tgatacgtgg tatggtggca agaaacctta
    11521 tgactatgga cgtttctttg aaaaagatgc cactcaccca gaagctcgaa aaggtgaaaa
    11581 atggtctgat tttgacctac gtaccatggt cgaaagaggc aaaaacaacc ctgctatctt
    11641 catgtggtca attggtaatg aaataggtga agctaatggt gatgcccact ctttagcaac
    11701 tgttaaacgt ttggtcaagg ttatcaagga tgttgataag actcgctatg ttaccatggg
    11761 agcagataaa ttccgtttcg gtaatggtag cggagggcat gagaaaattg ctgatgaact
    11821 cgatgctgtt ggatttaact attctgaaga taattacaaa gcccttagag ctaagcatcc
    11881 aaaatggttg atttatggat cagaaacatc ttcagctacc cgtacacgtg gaagttacta
    11941 tcgccctgaa cgtgaattga aacatagcaa tggacctgag cgtaattatg aacagtctga
    12001 ctatggtaat gatcgtgttg gttgggggaa aacagcaacc gcttcatgga cttttgaccg
    12061 tgacaacgct ggctatgctg gacagtttat ctggacaggt acggactata ttggtgaacc
    12121 tacaccatgg cacaaccaaa atcaaactcc tgttaagagc tcttactttg gtatcgtaga
    12181 tacagccggc attccaaaac atgacttcta cctctaccaa agccaatggg tttctgttaa
    12241 gaagaaaccg atggtacacc ttcttcctca ctggaactgg gaaaacaaag aattagcatc
    12301 caaagtagct gactcagaag gtaagattcc agttcgtgct tattcgaatg cttctagtgt
    12361 agaattgttc ttgaatggaa aatctcttgg tcttaagact ttcaataaaa aacaaaccag
    12421 cgatgggcgg acttaccaag aaggtgcaaa tgctaatgaa ctttatcttg aatggaaagt
    12481 tgcctatcaa ccgggtacct tggaagcaat tgctcgtgat gaatctggca aggaaattgc
    12541 tcgagataag attacgactg ctggtaagcc agcggcagtt cgtcttatta aggaagacca
    12601 tgcgattgca gcagatggaa aagacttgac ttacatctac tatgaaattg ttgacagcca
    12661 ggggaatgtg gttccaactg ctaataatct ggttcgcttc caattgcatg gccaaggtca
    12721 actggtcggt gtagataacg gagaacaagc cagccgtgaa cgctataagg cgcaagcaga
    12781 tggttcttgg attcgtaaag catttaatgg taaaggtgtt gccattgtca aatcaactga
    12841 acaagcaggg aaattcaccc ttactgccca ctctgatctc ttgaaatcga accaagtcac
    12901 tgtctttact ggtaagaaag aaggacaaga gaagactgtt ttggggacag aagtgccaaa
    12961 agtacagacc attattggag aggcacctga aatgcctacc actgttccgt ttgtatacag
    13021 tgatggtagc cgtgcagaac gtcctgtaac ctggtcttca gtagatgtga gcaagcctgg
    13081 tattgtaacg gtgaaaggta tggctgacgg acgagaagta gaagctcgtg tagaagtgat
    13141 tgctcttaaa tcagagctac cagttgtgaa acgtattgct ccaaatactg acttgaattc
    13201 tgtagacaaa tctgtttcct atgttttgac tgatggaagt gttgaagagt atgaagtgga
    13261 caagtgggag attgccgaag aagataaagc taagttagca attccaggtt ctcgtattca
    13321 agcgaccggt tatttagaag gtcaaccaat tcatgcaacc cttgtggtag aagaaggcaa
    13381 tcctgcggca cctgcagtac caactgtaac ggttggtggt gaagctgtca caggtcttac
    13441 tagtcaaaaa ccaatgcaat accgcactct tgcttatgga gctaagttgc cagaagtcac
    13501 agcaagtgct aaaaatgcag ctgttacagt tcttcaagca agcgcagcaa acggcatgcg
    13561 tgcgagcatc tttattcagc ctaaagatgg tggccctctt caaacctatg caattcaatt
    13621 ccttgaagaa gcgccaaaaa ttgctcactt gagcttgcaa gtggaaaaag ctgacagtct
    13681 caaagaagac caaactgtca aattgttggt tcgagctcac tatcaagatg gaacgcaagc
    13741 tgtattacca gctgataaag taaccttctc tacaagtggt gaaggggaag tcgcaattcg
    13801 taaaggaatg cttgagttac ataagccagg agcagtcact ctcaaagcgg aatatgaggg
    13861 agctaaaggc caagttgatc tcactatcca ggccaatact gagaagaaga ttgcgcaatc
    13921 tatccgtcca gtaaatgtag tgacagattt acaccaagaa cctactcttc cgtcaacagt
    13981 aacggttgag tatgacaaag gtttccctaa agctcacaaa gtcacttggc aagctattcc
    14041 gaaagaaaaa ctagactcct atcaaacctt tgaagtacta ggtaaagttg aaggaattga
    14101 ccttgaagcg cgtgcaagag tctctgtaga aggtatcgtt tcagttgaag aagtcagtgt
    14161 gacaactcca atcgcagaag caccacaatt accagaaagc gttcggacat atgattcaaa
    14221 tggtcacgtt tcatcagcta aggttgcatg ggatgcgatt cgtatagagc aatacgctaa
    14281 ggaaggtgtc tttacagtta atggtcgctt agaaggtact caattaacaa ctaaacttca
    14341 tgttcgcgta tctgctcaaa ctgagcaagg tgcaaacatt tctgaccaat ggaccggttc
    14401 agaattgcca cttgcctttg cttcagattc aaatccaagc gacccagttt caaatgttaa
    14461 tgacaagctc atttcctaca ataaccaacc agccaatcgt tggacaaact ggaatcgtag
    14521 taatccagaa gcttcagtcg gtgttctgtt tggagattca ggtatcttga gcaaacgctc
    14581 cgttgataat ctaagtgtcg gattccatga agaccatgga gttggtgcac cgaagtctta
    14641 tgtgattgag tattatgttg gcaagactgt cccaacagct cctaaaaacc ctagttttgt
    14701 tggtaatgag gaccatgtct ttaatgattc tgccaactgg aaaccagtta ctaatctaaa
    14761 agcccctgct aaactcaagg ctggagaaat gaaccacttt agctttgata aagttgaaac
    14821 ctatgctatt cgtattcgca tggttaaagc agataacaag cgtggaacgt ctatcacaga
    14881 ggtacaaatc tttgcgaaac aagttgcggc agccaaacaa ggacaaacaa gaatccaagt
    14941 tgacggcaaa gacttagcaa acttcaaccc tgatttgaca gactactacc ttgagtctgt
    15001 agatggaaaa gttccggcag tcacagcaag tgttagcaac aatggtctcg ctaccgtcgt
    15061 tccaagcgtt cgtgaaggtg agccagttcg tgtcatcgcg aaagctgaaa atggcgacat
    15121 cttaggagaa taccgtctgc acttcactaa ggataagaac ttactttctc ataaaccagt
    15181 tgctgcggtt aaacaagctc gcttgctaca agtaggtcaa gcacttgaat tgccgactaa
    15241 ggttccagtt tacttcacag gtaaagacgg ctacgaaaca aaagatttgt cagttgaatg
    15301 ggaagaagtt ccagcagaaa atctgacaaa agcaggtcaa tttaccgttc gaggccatgt
    15361 ccttggtagt gatcttgttg ctgaggtcac tgtacgagtg acagacaaac taggcgaagc
    15421 tctttcagat aaccctaact atgatgaaaa cagtaaccag gcctttgctt cagcaaccaa
    15481 tgatattgac aaaaactctc atgaccgcgt tgactatctc aatgacggag atcattcaga
    15541 aaatcgtcgt tggacaaact ggtctccaac accatcttct aatccagaag tatcagcggg
    15601 tgtgatcttc cgtgaaaatg gtaagattgt agaacggact gttgcgcaag ccaaacttca
    15661 cttctttgca gatagtggta cggatgcacc aactaaactc gttttagaac gctatgtcgg
    15721 tccagagttt gaagtgccaa cctactattc aaactaccaa gcctacgacg cagaccatcc
    15781 attcaacaat ccagaaaatt gggaagctgt gccttatcgt gcggataaag acattgaagc
    15841 cggtgatgaa atcaacgtaa catttaaagc tgtcaaagcc aaagccatga gatggcgtat
    15901 ggagcgtaaa gcagataaga gcggtgttgc gatgattgag atgaccttcc ttgcaccgag
    15961 tgaattgcct caagaaagca ctcaatcgaa gattcttgta gatggaaaag agcttgctga
    16021 tttcgctgaa aatcgtcaag actatcaaat tacctataaa ggtcaacggc caaaagtctc
    16081 agttgaagaa aataatcaag tagcttcaac tgtggtagat agtggagaag atagccttcc
    16141 agtacttgtt cgcctcgttt cagaaagtgg aaaacaagtc aaggaatacc gtatccactt
    16201 gactaaggaa aaaccagttt ctgagaagac agttgctgct gtacaagaag atcttccaaa
    16261 actcgaattt gttgaaaaag atttggccta caagacagtt gagaaaaaag attcaacact
    16321 gtatctaggt gaaactcgtg tagaacaaga aggaaaaact ggtaaagaac gtatctttac
    16381 agcgattaat cctgatggaa gtaaggaaga aaaactccgt gaagtggtag aagctccgac
    16441 agaccgcatc gtcttggttg gaaccaaacc agtagctcaa gaagctaaaa aaccacaagt
    16501 gtcagaaaaa gcagatacaa aaccaattga ttcaagtgaa gctagtcaaa ctaataaagc
    16561 ccagttacca aatacaggta gtgcgtcaag ccaagcagca gtagcagcag gtttagctct
    16621 tctaggtttg agtgcaggat tagtagttac taaaggtaaa aaagaagact agaaattttg
    16681 ataccttctt tatcattaaa gaccaaagaa aaactcttgt cctaaataga agataaagag
    16741 tctggaacaa aatagttctc aaccacaaaa aagctagata tttccaattg cggaactcta
    16801 gctttttaat tttgagtcgt tctcttattg tatagtagat tgaaactaga gtagtacact
    16861 tctacttcta aaacattgtt agaaatcgat ttgactgtcc ttatcgattt gtcctggtct
    16921 tatttcattt cactatgttt taggaggtta ttggccataa gtaccaatcc catgtcaatt
    16981 ctcacttgac gcttgcctct cagattacat ctcttgtaac ccaaagaagc ctttatctgt
    17041 ccaaagacag gttccacatc aatcttgcgt tgagcgaaaa tctgtctacc ttggggagat
    17101 aaaagcgcct gacattcttt agctttcaag ttttgatagc gttcgttcat atacagtccc
    17161 ttttgagggg ctgattcagg ttcgtcggcg tagtaaacct tgatttcttg ttgaaagtct
    17221 gtctgtgttt tctgatattt ggtatggtga aaacgataat accagccatc aggatgtgta
    17281 tagctatcct ccttgtcatt atagtgccaa ttcgctaagt ttttagctga ctgtttatac
    17341 cctctctttt gttccttatc aaacatggca tatttaatca ggaggggagt gatttcttct
    17401 tgaaaataga cttgtatctg ttcttgaagt ttggcggaga atttctctgt cgttttcttc
    17461 cacacaaaac tatacttgtt ggcattggct tcaatcttag ttccgtcaat aaacaaacaa
    17521 tctaaggtca ctaactcttc catttttcaa tttttcgacc agagaaaatc ccttgtgaat
    17581 aggcaaatag aagagtagat acaagcattt tagggtgata agacgggcga tcaaaggcat
    17641 gataggaggt gtagaagtga cgttcctcca aggtattcac cactttttca atagtaaaga
    17701 cgagatggtc ttgtggtaag aaggaactga tttctagtgg taaagttgtt tgatttgtgt
    17761 tatagtgaat atgcatggga tagcctttct aaatggttta ttaagcaatt ctattttacc
    17821 aagactatcg taaccatgca aaaaagcaac ggcaaatccg ttgccttttt ggatataaga
    17881 gactattgtc ccagactctt ttctttgtat aaaattgtat agtgttattg tctatactat
    17941 tttgtagaga aagcaaaaat ccctagaaaa tgcttaggga ttcgactatt tcattaagaa
    18001 caattcaaca atcatttcta tatacatgat aagggttaat aagaatcctg cacgccagaa
    18061 gaatttgatg aatttaggat agtaaaagct gcgttttttc aaaaggaaga aaaagacgag
    18121 aataatggct aggatcgaga gggctagccc cagtctaggg aggaaattat gggtaaaggt
    18181 tttagctgta atcaagtaat actcaaatac caagactgga aaagccaaat ccgcaaagtt
    18241 tcgtcctagt ttttttaatc taaaaagttt ggttaggata atgcagatga ctaaggtcag
    18301 tatcaataat aaaatagatg ctaatttcat taaaatcata cccatattgt atcataaaaa
    18361 aaggctaatg gaaacgagaa acagaggaat ttataggaaa gtcaggcttt tgagattgtg
    18421 ggtgattttt gttataatga aagttataaa atcttataat accttataat accttgaatg
    18481 attattatcg aaaactcttt ggagaaaaga cttttaaagt ccctattgat gcgggatttg
    18541 actgtcccaa tcgtgatgga actgtggctc atggaggttg tactttttgt acggtttcag
    18601 gttctggaga tgctattgta gccccagatg cgcctatccg tgagcaattt tataaggaaa
    18661 ttgactttat gcaccgtaag tggccggatg ttcagaagta tctggtttat tttcaaaatt
    18721 ttaccaacac ccatgaaaag gtggaagtta ttcgagagcg ttatgaacag gctatcaatg
    18781 agccaggtgt ggtaggtatc aatattggaa cgcgcccaga ctgtttacca gacgaaacca
    18841 tcgaatattt ggctgagtta tcggagtgca tgcatgtgat ggttaaattg ggcttgtaga
    18901 ctacttatga agcaacttct gacctgatta accgtgcgta ttcttatgaa ttgtaggtgg
    18961 aaacggtcaa gcgtttgaga aagtatccca agattgagat tgtttcccat ttgatcaatg
    19021 gtttgcctgg tgaaacccat gagatgatgg ttgaaaatgt ccgccgttgt gtcacgaata
    19081 acgatattca agggattaaa ctgcatttgc tccatcttat gacaaatact cgtatgcaac
    19141 gagattacca tgagggacgt ttacaattga tgagtcagga cgaatatatc agggtcatct
    19201 gtgaccaact ggaaatcatt cccaaacata tcgtcatcca tcgaatcaca ggagatgcac
    19261 ctagggatat gctgcttggg cttatgtgga gcctcaataa atgggaagct ctcaacagca
    19321 ttgagatgga gatgcgacgt cgtggaagtg ttcaaggatg caaggctgta aaacaggagt
    19381 ttgaaaatga aaagaccact tgagatggca catgattttt tggctgaggt cgtgacaaaa
    19441 gaggatgtcg tagtggatgc gactatggga aatggtcatg acacgctttt tttagccaag
    19501 ctagccaagc aagtctatgc ctttgatatt cagaagcaag ccttggaaaa gacccaagag
    19561 cgtttgcatc aggctgactt gacaaatgcc cagttaatct tgcaaggcca tgagacactg
    19621 gaccagtttg tgacaaaagc taaggcaggg atttttaatc tgggctattt gccgtcagct
    19681 gataagtctg tcatcacccg accgcagaca acgattgagg cattagaaaa gctatgtggc
    19741 ttacttgtca aaggtggacg aattgctatt atgatttact atggtcatga aggaggcgat
    19801 ctcgagagag atgctgtctt ggattttgtg atccagttga accaacaaga gtacacagct
    19861 gccatttacc gaactttaaa ccaagtcaac aacccgccgt ttttagtgat gattgaaaaa
    19921 ttagagagat acagacatgg ataaacaata cctacacgaa aagctggatg ccatgcgcca
    19981 gaattttgtt gaatcaaccc accacgaacg agcggtgggc gtgctagacc aagcgcatat
    20041 gagcaaaaaa atgcttaaaa tcaagaaaaa attagttgct cttgaaatgg aacggtgcca
    20101 gagaaaaatt gagcacaaag actgttccaa gattgaccaa aaaatcaaag agcagaagga
    20161 gatatttgaa tcctgttgta aaaaagatta aggaggacgt gcgtggaatt actgatttac
    20221 ctcatcctat ttttactggt cttgattgtc tcaagtacaa ccaataagct cctacccttt
    20281 ttgcctctcc ctttggttca gattcttttg ggaattgtga ttggtctctt tttacccaat
    20341 actgactttc accttaatac ggagttgttt ttggcactgg ttatcggacc cttgcttttc
    20401 cgagaggctg aagaagcaga tgttacggct attttaaaac actggcgaat cattgtttat
    20461 ctcatatttc cagtgatttt tatctcgacc ctgagtttgg gtggcttggc ccatcttctt
    20521 tggttcagcc ttcccttggc agcttgcttg gctgttgggg cagcccttgg tcctacggac
    20581 ttggtggcct ttgcctctct ttcggagcgt tttagctttc ctaagcgcgt gtccaatatt
    20641 cttaagggcg aaggactctt gaatgatgct tctggtttgg tggcttttca ggtagctttg
    20701 acagcttgga caactggagc tttttctctg gggcaagcta gcagttcgct catcttttca
    20761 attctaggcg gttttttaat tggattttta acagctatga ccaaccgctt cctccatacc
    20821 ttcttgctaa gtgtgcgcgc aacggatatt gccagtgaac ttttattaga gttgagtttg
    20881 cctctagtga ccttctttct ggcagaagaa gtccatgttt cagggattat tgccgtcgta
    20941 gttgctggaa ttttaaaggc aagtcgcttc aagaaaatca cgctcctcga agcccaagtg
    21001 gatacggtga ccgagacggt ctggcataca gtgaccttta tgctcaacgg ttctgtcttt
    21061 gtgattttag ggatggagtt ggaaatgata gcagaaccta tcttgaccaa tccaatctat
    21121 aatcctctac ttttattgct atctctcatc gcccttacct ttgtcctctt tgtcattcgt
    21181 tttattatga tctatggcta ttatgcctat agaacccgac gcctcaagaa aaagctaaat
    21241 aagtatatga aggacatgtt tctcttgacc ttttcaggtg ttaagggaac ggtgtcgatt
    21301 gctacgattc tcttgatacc aagtaatcta gaacaggagt atcctctctt gcttttcctt
    21361 gttgcaggtg tgacgcttgt cagcttttta acaggtctct tggtcttgcc tcatctttct
    21421 gatgaagagg aagaaagcaa ggattatctc atgcatatcg ccattttgaa tgaagtaacg
    21481 ctagagttgg aaaaagagtt ggaagacacc agaaataaac ttcccctcta tgcggctatt
    21541 gacaattatc atggacgtat tgaaaatctc attttaagcc aagaaaacca ggatgatcaa
    21601 gaagactggg ctgctttgaa actcttgatt cttagtattg aaagtgatgg tttggaacag
    21661 gcctatgaag aggggaacat tagcaatcgt gcttaccgag tttaccaacg ttatctgaaa
    21721 aatatagaac aaggaatcaa tcgtaaactt gcctcaagac tgacctatta ttttcttgtt
    21781 tccttgagga ttttacgttt tctccttcat gaagttttta ctcttggaaa gaccttccgt
    21841 agctggaagg acaaggagca aagccgtctc cgtgctcttg attatgacca aattgcagag
    21901 ctctatcttg ccaatacaga gatgattatt gaaagtttgg aaaacctgaa gggagtctac
    21961 agacgctctt tgattagttt tatgcaggag tctcgtcttc gagaaacagc tattatcagc
    22021 agtggtgcct ttgtcgaacg ggttatcaat cgtgtcaaac ccaacaatat cgatgaaatg
    22081 ctgagaggct attatctgga gcgcaagttg attttcgaat acgaagaaaa acgattgatt
    22141 acgactaagt atgccaagaa attacgacaa aatgtaaata acttagagaa ctattccttg
    22201 aaggaagctg ccaataccct accgtatgat atggtggaat tggtaagaag aaattagtta
    22261 atactcttcg aaaatctctt caaaccacgt cagcgtcgcc ttaccgtatg tatgtgactg
    22321 acttcgtcag tcttatctac aacctcaaaa cagtgttttg agcagcttgc ggctagcttt
    22381 ctagtttgct ctttgatttt cattgagtat aagattataa gtgaaggagt atgacatgaa
    22441 aaagtggtgg aaagagctga tagacaaacc tttattaaaa gcttttttgc attattatca
    22501 agcatcagat agtgagttga ccagtgtcgc agtagcctac tattggttga tttcgatttt
    22561 ccccctgctt ttggtggtgg tcaatatcct cccctatttt cagattcctg tgggagaatt
    22621 tctgggcttt atgaaagacg tcctgccccc aagcctctat gaaggtgtgg aaaaaatagc
    22681 cagagaagtc ttgacgcaac cttcaacagg tttattgagt ttttctgttt tatcggcgtt
    22741 atggagtttt tcaaaatcta tgaatttctt gcaaaaagct tttaacaagg cttatggcgt
    22801 cgaaaagagt cgtggactta tttcccatca gatgctaagt ctcctagtca gttttggctt
    22861 gcagctcctc tttgcgtttg ccttgttttt gatcttattt ggtcagatga ttttggcttt
    22921 acttgctcat tattggacaa aagatggcat tatctatcag gctttacaag ggttggcagg
    22981 tcctctgatt tacgccctcc tctttgctat cttggtcatg ctttattatt ttcttcccaa
    23041 tctatctaac aggaaaatta gctataccct accaggcagt gcctttgttc tcttagtgat
    23101 tttaggttta ctaactctgt tctctagtta tctcaattac tatgtccatc atttggtgga
    23161 tgtccgaatt ttaggttccg ttcttcttgt tgttatgatg ttttggttta tcttgattgc
    23221 taaaattgtt atcctaggcg cggttatcaa tgccagtatg cagagtttga aagatccggt
    23281 ctttaaaaaa gactaactat ttatccatta taaaagcgca tagtatcaag actttataga
    23341 accttgatac tatgcgcttt tgtgctttga cagttttttg tatagttttt gtccaagatt
    23401 tctaaatcat ctgattaaat tcctattttc ccctatcatt gtccctgttt tttcgaaaat
    23461 ggaaggagta taataaatct atcaataaaa tgataggagg aactttatgg gtcatatttt
    23521 cttttttcta agtgtctttt tggcagggat tctatccttc ttttctcctt gtatcttacc
    23581 tttgttaccg gtctatacag gggtgttact agatgataag gatggtgctc aggcttctag
    23641 cggcaaattt tcaatctcag ttactagttt attacgaact ctggccttta tagcaggaat
    23701 ttcctttata tttattttgt tgggctatgg agctggtttt ttaggcgatt tgctttatgc
    23761 ttcttggttc caatatctta ctggggcaat tattatcctt cttggtttgc accaaatgga
    23821 gattctacac tttaaggggc tttataagga aaagaggcta caactgcaag gacaggggca
    23881 aaatggtaag ggctatagtc aggcattttt attgggcttg acctttagtt ttgcttggac
    23941 gccttgcgtg gggccggttc tagggtctgt tttggccttg gcggcttcag gtggttcagg
    24001 agcttggcag ggagctggtc tcatgttggt gtatacgctg ggcttggcgc taccattctt
    24061 gcttctagct ctgacctcta gttatgtttt gaaacatttc cgaaaacttc atccctatct
    24121 cggaatcctc aaaaaagtgg gaggttttct cattattgtg atgggactct tggttctgtt
    24181 tggaaatgct tcaattttaa gtcaattatt tgaataaaat ggaaaggaat atcaatatga
    24241 aaaaatggca aacatgtgtt cttggagcgg gttcgctcct ttgtttgacg gcttgttcag
    24301 gcaagtccgt gactagtgaa caccaaacga aagatgaaat gaagacggag cagacagcta
    24361 gtaaaacaag cgcagctaaa gggaaagagg tggctgattt tgaattgatg ggagtagatg
    24421 gcaagaccta ccgtttatct gattacaagg gcaagaaagt ctatctcaaa ttctgggctt
    24481 cttggtgttc catctgtctg gctagtcttc cagatacgga tgagattgct aaagaagctg
    24541 gtgatgacta tgtggtcttg acagtagtgt caccaggaca taagggagag caatctgaag
    24601 cggactttaa gaattggtat aagggattgg attataaaaa tctcccagtc ctagttgacc
    24661 catcaggcaa acttttggaa acttatggtg tccgttctta cccaacccaa gcctttatag
    24721 acaaagaagg caagctggtc aaaacacatc caggattcat ggaaaaagat gcaattttgc
    24781 aaactttgaa ggaattagcc taggaggtgt cttatgaatg ataagttaaa aatcttcttg
    24841 ttgctaggag tattttttct agccataacc ggtttctatg ttctattgat acgaaatgca
    24901 gggcagacag atgcctcgca aattgaaaag gcggcagtta gccaaggagg aaaagcagtg
    24961 aaaaaaacag aaattagtaa agacgcagac ttgcacgaaa tttatctagc tggaggttgt
    25021 ttctggggag tggaggaata tttctcacgc gttcccgggg tgacggatgc cgtttcaggc
    25081 tatgcaaatg gtagaggaga aacaaccaag tacgaattga ttaaccaaac aggtcatgca
    25141 gaaaccgtcc atgtcaccta tgatgccaag caaatttctc tcaaggaaat cctgcttcac
    25201 tatttccgca ttatcaatcc aaccagcaaa aataaacaag gaaatgatgt ggggacccag
    25261 taccgtactg gtgtttatta cacagatgac aaggatttgg aagtgattaa ccaagtcttt
    25321 gatgaggtgg ctaagaaata cgatcaacct ctagcagttg aaaaggaaaa cttgaagaat
    25381 tttgtggtgg ctgaggatta ccatcaagac tatctcaaga aaaatccaaa tggctactgc
    25441 catatcaatg ttaatcaggc ggcctatcct gtcattgatg ccagcaaata tccaaaacca
    25501 agtgatgagg aattgaaaaa gaccctgtca cctgaggagt atgcagttac ccaggaaaat
    25561 caaacagaac gagctttctc aaaccgttac tgggataaat ttgaatccgg tatctatgtg
    25621 gatatagcaa ctggggaacc tctcttttca tcaaaagaca aatttgagtc tggttgtggc
    25681 tggcctagtt ttacccaacc catcagtcca gatgttgtca cctacaagga agataagtcc
    25741 tacaatatga cgcgtatgga agtgcggagc cgagtaggag attctcacct tgggcatgtc
    25801 tttacggatg gtccacagga caagggcggc ttacgttact gtatcaatag cctctctatc
    25861 cgctttattc ccaaagacca aatggaagaa aaaggctacg cttatttact agattatgtt
    25921 gattaatact cttcgaaaat ctcttcaaac cacgtcagcg tcgccttacc gtatgtaggg
    25981 tt
//
LOCUS       DBERPV010000027        25286 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.27, whole genome shotgun sequence.
ACCESSION   DBERPV010000027 DBERPV010000000
VERSION     DBERPV010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 25286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25286
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.27"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            213..1694
                     /gene="mgaSpn"
                     /locus_tag="ACL8C7_001439"
                     /gene_synonym="mgrA"
     CDS             213..1694
                     /gene="mgaSpn"
                     /locus_tag="ACL8C7_001439"
                     /gene_synonym="mgrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor transcriptional regulator
                     MgaSpn"
                     /protein_id="HGS1395618.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            2056..3057
                     /locus_tag="ACL8C7_001440"
     CDS             2056..3057
                     /locus_tag="ACL8C7_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS1395619.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPFSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILKKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            3207..4124
                     /locus_tag="ACL8C7_001441"
     CDS             3207..4124
                     /locus_tag="ACL8C7_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1395620.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            4135..5025
                     /locus_tag="ACL8C7_001442"
     CDS             4135..5025
                     /locus_tag="ACL8C7_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS1395621.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            5054..6670
                     /locus_tag="ACL8C7_001443"
                     /pseudo
     CDS             5054..6670
                     /locus_tag="ACL8C7_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            6680..7999
                     /locus_tag="ACL8C7_001444"
     CDS             6680..7999
                     /locus_tag="ACL8C7_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HGS1395622.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKIEQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKNNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            8396..8809
                     /locus_tag="ACL8C7_001445"
     CDS             8396..8809
                     /locus_tag="ACL8C7_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395623.1"
                     /translation="MKNNERLGIKLSRDSVLGLREVRRLYLGSSDIPVPDGYVIEVAY
                     KQISNEIDIIDWVELNKSKIKISEISESVDIDATSLRTTLTLDTLVYEGMRDIQLKLR
                     ELTKGRVFFSFVVKLVLFASILKKKGLLEKFQEKC"
     gene            9047..9346
                     /locus_tag="ACL8C7_001446"
     CDS             9047..9346
                     /locus_tag="ACL8C7_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395624.1"
                     /translation="MNRNVLEFLKTETAEKISLFIRKINGLEGNVTLLSINSQDLEDI
                     KNAMLSNSNLGLKIARLDVMKKIAYASNRTHYKDGTTIMDDISSGKIHRRPKSYI"
     gene            9400..9621
                     /locus_tag="ACL8C7_001447"
     CDS             9400..9621
                     /locus_tag="ACL8C7_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000916559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395625.1"
                     /translation="MLKNFCQNAFISLYFIVSLLGGFSAQVDLKSFSPYQSMKIALLL
                     GVALILLQLPIMFAKLLEALKTKKGETHE"
     gene            9837..11156
                     /locus_tag="ACL8C7_001448"
     CDS             9837..11156
                     /locus_tag="ACL8C7_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HGS1395626.1"
                     /translation="MFKIKQTASLSDHYFLNTSKLRSIRWFTIGFLSILSLSSSILFK
                     GWFLQMITLSVGLIITLYIERKIKGWAQQIEPLLIVRENLLFMLRRNSFLFTATKDGA
                     ILRSARFNYQLNDVSIVIQALKSGDEFTREMETLEVLLSSTLGISLSSKEIYATHVEY
                     VFVYRQPERLHVTSLPLEDDSLKIKIYDDFVIDLRKNFSMLISGASGSGKSFFTYYYL
                     TRFISQTVNGKHAKIYVIDPKFSDIYKLCEFSGFPVENYGTTNEDAFRIVRHYINEMN
                     RRMEIYNKSDLFNSICIDLGFPPLLLIIEEYSSLVASMDAKAKKDFENMVAIVAQKAR
                     SLSMGVCIVMQQPRSDSLSTNIREQLVNAIFLGAPTRESSQMVFGTTDVPKVQKGKGV
                     GLYSIEREPPKEFHSPMFDRDVFETIFSIWEFASKDYAKDYMKDEDV"
     gene            11334..11597
                     /locus_tag="ACL8C7_001449"
     CDS             11334..11597
                     /locus_tag="ACL8C7_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395627.1"
                     /translation="MKETVVVLAISTKKDRGWVRVSTANNCWSDLGMHFDKSKFGAVF
                     SAPGLYEVEVINNASFGQNAQYEVIQSRKLGTFAELIEMAKIK"
     gene            11722..12765
                     /locus_tag="ACL8C7_001450"
     CDS             11722..12765
                     /locus_tag="ACL8C7_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HGS1395628.1"
                     /translation="MNKEVLNRAPSNSPITIHQMSNKSYSKFQEEVSLKYGFIGLKLD
                     KLSLTAEVSEEFHSEILSGNFTLYDYFGVVEPNLNRNGELASYKGQFFNDEKENWYIE
                     YTPVASIKMNKRPLKIEFTPSKVSKKNFLIVFHRMFPYMFNIAISTFHLAYDFERDLS
                     ALRVNWPKVMYRPIYKGMKLETMDFGAPKGNYHLTAYNKLKERMDSGDMAEIEIYQQY
                     DNLWRIEYKFYNEGNIKKELKNGLPFLAKIPVYIENFKGLEFNNLGVNEKIYLFALRN
                     KPELFAESDKRTVAKYKKLAESISEVNLNVFFQNALDFVEIFNQEPCLINFFEFMNSM
                     LQGDIPKLTINQE"
     gene            12781..12963
                     /locus_tag="ACL8C7_001451"
     CDS             12781..12963
                     /locus_tag="ACL8C7_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HGS1395629.1"
                     /translation="MKDTISNKDLISMGYRPSTANAIIHQARELLVSRGYTFYNRKRL
                     MVVPKGVVKELLGMEL"
     gene            12965..14092
                     /locus_tag="ACL8C7_001452"
     CDS             12965..14092
                     /locus_tag="ACL8C7_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGS1395630.1"
                     /translation="MAYIEYKQRGKKRLWSFSIRERSKSLLHKSGFKTKREAKIEAEK
                     VLHKLNTGSVLSSSMTLSELYNEWLDLKILPSNRSVVTKKKYLMRKKVIERLFGNKPV
                     SQIKPSEYQKIMNEYGETVSRNFLGRLNSCIRASIQMAIADKVIIEDFTAYVELFSSK
                     SGQKVEEKYLHAESDYQKVLVYLKNKFDYQKSIVPYVIYFLFKTGMRFSELIALTWDE
                     VDELNEQLKTYRRYNTAIHKFTPPKNNTSIRLVPITSDMLSLLKTLKILQLKTNKELN
                     IDNENNLIFQHFGYVYDVPDIATVNKAIKVMLKELQIFPLITTKGARHTYGSYLWHNN
                     IDLGVIAKILGHKDISMLIDVYGHTLEEKISEEFMAVKSLL"
     gene            complement(14175..14247)
                     /locus_tag="ACL8C7_001453"
     tRNA            complement(14175..14247)
                     /locus_tag="ACL8C7_001453"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14212..14214),aa:Lys,seq:ctt)
     gene            complement(14512..15783)
                     /locus_tag="ACL8C7_001454"
     CDS             complement(14512..15783)
                     /locus_tag="ACL8C7_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HGS1395631.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            16053..16253
                     /locus_tag="ACL8C7_001455"
     CDS             16053..16253
                     /locus_tag="ACL8C7_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395632.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQ"
     gene            16457..16636
                     /locus_tag="ACL8C7_001456"
     CDS             16457..16636
                     /locus_tag="ACL8C7_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395633.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            16773..16952
                     /locus_tag="ACL8C7_001457"
     CDS             16773..16952
                     /locus_tag="ACL8C7_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HGS1395634.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERLITIPHGE
                     LNKYTERGIRKQAGL"
     gene            16989..17441
                     /locus_tag="ACL8C7_001458"
     CDS             16989..17441
                     /locus_tag="ACL8C7_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HGS1395635.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            17732..18202
                     /locus_tag="ACL8C7_001459"
     CDS             17732..18202
                     /locus_tag="ACL8C7_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HGS1395636.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVLSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            18221..19288
                     /locus_tag="ACL8C7_001460"
     CDS             18221..19288
                     /locus_tag="ACL8C7_001460"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M50 family metallopeptidase"
                     /protein_id="HGS1395637.1"
                     /translation="MKKIGTYLVYVLAFVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVGITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKELAEGV"
     gene            19290..19718
                     /locus_tag="ACL8C7_001461"
     CDS             19290..19718
                     /locus_tag="ACL8C7_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGS1395638.1"
                     /translation="MEIEISDFTGCKIALFCGDKLLTILRDDKDDIPCPNMWELSGGG
                     REGDESPFECARREVYEELGIHLDEDCLLWSKIYPSVIFKGKKSVFMVGQLRQEQFDN
                     IIFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            19856..20806
                     /gene="prmA"
                     /locus_tag="ACL8C7_001462"
     CDS             19856..20806
                     /gene="prmA"
                     /locus_tag="ACL8C7_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HGS1395639.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARISELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     IFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKW
                     DMVRELAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            20808..21551
                     /locus_tag="ACL8C7_001463"
     CDS             20808..21551
                     /locus_tag="ACL8C7_001463"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HGS1395640.1"
                     /translation="MQQYFVKGSAISPVTIENKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLTQLDQ
                     FDSIIVAYEESGKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            21562..23358
                     /gene="pepF"
                     /locus_tag="ACL8C7_001464"
     CDS             21562..23358
                     /gene="pepF"
                     /locus_tag="ACL8C7_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HGS1395641.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            23605..24396
                     /locus_tag="ACL8C7_001465"
     CDS             23605..24396
                     /locus_tag="ACL8C7_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HGS1395642.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLLDHLGDPSPEIRDDLVFTSF
                     ARGIQEELFTQEQFHFIAEGVSSDVGLDKEIDKVGLPTLERSFRALVYANLLYADANQ
                     QSVFYQGLQLEIRNVFSNQGLHYLSKEKDTTGFSSQYGWVHAFAHGADLLTEVVCHPD
                     FPINRIHEVFDILGQLFKRMSIRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVD
                     FPIEEREDFSKFSNFRSCLVEVYVQLDQRNSLQDELKEAIQSFQY"
     gene            24507..25175
                     /locus_tag="ACL8C7_001466"
     CDS             24507..25175
                     /locus_tag="ACL8C7_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HGS1395643.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGFDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGPIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
BASE COUNT         7943 a         4109 c         5359 g         7875 t
ORIGIN      
        1 attaaaaata taatctttag acttgaattt gattctgtat tcacgccctc aatagacggt
       61 aaaataagaa aattgtttat atattgtctc cgtagtgtta ttatacgaaa taaaagattt
      121 taggaaaagt cgttatatca tgctatacct attctttgtg gtataattgc aagaggttta
      181 atccgataat ttataaagag agaaagatat tcatgagaga tttattatct aaaaaaagtc
      241 ataggcaatt agaattatta gaattattat ttgaacataa acgttggttt catcgttctg
      301 aactagcaga gttattaaat tgtacagaac gtgcagtcaa agatgatcta tcccatgtta
      361 aatctgcttt tcctgacttg atttttcatt cttctactaa tggtatacgc attattaata
      421 ccgatgatag tgatattgaa atggtttacc atcatttctt taaacattca actcattttt
      481 cgattttaga attcatcttc tttaatgaag gttgtcaagc tgagagtatt tgtaaagaat
      541 tttatatcag ttcatcttcg ctctatcgta ttattagcca aatcaataaa gtgattaaaa
      601 ggcaatttca atttgaagtc agtctgaccc ctgttcaaat cattggaaat gagagagaca
      661 ttcgttactt ttttgcacaa tatttttcag aaaaatatta tttcctagaa tggccatttg
      721 aaaatttttc atcagagcca ctatctcaat tgttagaatt ggtttataag gaaacaagct
      781 ttccaatgaa tttgtcaacg catagaatgc taaagttgct cctagttacg aacctatata
      841 gaataaagtt tggtcatttt atggaagtag ataaagattc ttttaacgac caaagtttgg
      901 attttttaat gcaggcagaa ggaatagaag gtgttgctca gagttttgaa tcagaataca
      961 atatctcttt agatgaagaa gttgtttgcc aattatttgt gtcttacttt caaaaaatgt
     1021 ttttcataga tgaaagtctc tttatgaaat gcgtaaaaaa ggatagttat gttgaaaaat
     1081 cttaccatct attgagtgat tttattgatc agatttcagt caagtatcag attgaaatgg
     1141 agaataagga taatctgatt tggcatctgc ataataccgc acatctgtat cgtcaagagt
     1201 tgtttactga gtttatttta tttgatcaaa aagggaatac aatcaggaac tttcaaaata
     1261 tttttccaaa atttgtttca gatataaaaa aagagctttc tcactattta gagactcttg
     1321 aggtttgttc tagttcaatg atggtaaatc atctatctta taccttcatc actcatacca
     1381 aacatttggt gattaatttg ctacaaaatc agcctaaact aaaggttttg gttatgagta
     1441 attttgatca gtatcatgca aaattcgttg cagagacact ttcttattac tgtagcaata
     1501 attttgaact ggaagtttgg actgaattag aattatcaaa ggaatcttta gaagattcac
     1561 cttatgatat cattatttct aattttatta ttcctcctat tgaaaataag agactcatct
     1621 attcaaataa tataaacacg gtctcactca tatatttgtt aaatgccatg atgtttattc
     1681 gattagatga gtaaccaaaa ataacaaaaa aacgctattt cgcgtttgaa ctgtacctca
     1741 aaagttagac agaaaaaatc taatttttgg ggtgtttttg ttaagaaaag accttcaatc
     1801 atttaagcaa aatgtacatc tagatttata gccctctaaa actcttgctt tttttgtaga
     1861 agatacgaaa aaagccataa aaccaaggct tttcctgttt tatgtagatg tttacacatg
     1921 aaaattgaag tattttcaaa agctaattgg agtgatttta ttcatgatgg gataaatgat
     1981 ctggccaaaa atgattgaga aatagttgct taaaaagcat ttgcatgata ctatatattg
     2041 aaaggaggtg ataatatggt agaacaaaga aaatcaatta ccatgaaaga tgttgcttta
     2101 gaagcaggag ttagtgttgg aactgtttca cgtgtaatta ataaagaaaa aggcattaaa
     2161 gaagtaactt tgaaaaaagt ggaacaagcg attaaaactt tgaattacat tccagattac
     2221 tacgctagag gaatgaaaaa aaatcgaaca gaaacgattg caatcattgt accaagtatc
     2281 tggcatccct tcttttcaga atttgctatg catgtggaaa atgaagtcta taagagaaat
     2341 aacaaattac tcttatgttc tatcaatggt acaaatagag agcaagacta tctggagatg
     2401 ttgcgtcata ataaagttga tggagtggtt gccattacct atagtccaat tgaacattac
     2461 ttgacgtcag gaattccctt tgttagtatt gaccgcacat actcagatat tgccattcct
     2521 tgtgtttcat cagataatga tgcaggtgga agagaagcag ctaaacaatt aattagtaaa
     2581 ggatgtcagc atttagcctt tgtgggcgga cataatacaa ccattaatga aaccaaacgt
     2641 cgtagaattt catttgaaaa gtatgtccaa gagcataaaa taccttttag tatttttgat
     2701 ttggatgaga cagttactga ctattatgga aagctagaga gtttcttgga agaaaattct
     2761 tctatagatg gaatttttac aatcaacgat tttacagctt tggatgtgat tgaaatacta
     2821 aaaaaaaatg gcaaacgtat tcctcatgat gtccaaatta ttggatacga tggaattaaa
     2881 atggctggag atagagatta tctactttca actattgaac aaccattgga agaaatggca
     2941 aaagaagcgg ttcgtatttt gtttgatata attgatggaa agactgttaa tttgcagaca
     3001 atcctaccag taaaatttgt tgaaggaaaa acaacaaaaa atgaaaataa gtcttgacag
     3061 aaagcgctat caatgataga atgaattcag ataaaaagat ttatttttaa aacaaaaatg
     3121 aaacgtttca aaaaaagaaa taaagagaca gcgtcaagcg ctatcttttc tagaaaaaaa
     3181 tgaaacgttt caaaaaggag gttgctatga atagcaaagc gaagcaagtt tctctttggg
     3241 aaagaatcaa gaaacaaaaa ctcttgttat tgatgactgt ccccggttta gttttaacct
     3301 ttatctttaa atacatccct atgtatgggg tcttaatcgc atttaaagat tacaatcctt
     3361 taaaaggaat tttagggagt gattggattg gtttttctga gtttacaaaa ttcatatcct
     3421 ctcccaactt tggtatcttg ttagccaaca cattaaaatt aagtatctat ggtttattgc
     3481 ttggcttttt accaccaatc attcttgcta ttatgctcaa tcaactcttg agtgaaaaag
     3541 tcaaaaaacg aattcagctc attttatacg caccaaactt tatctcagtc gttgttattg
     3601 tcggtatgat tttcctcttc ttttcagtgg gaggaccaat caacaatttt ctttctatgt
     3661 ttggaatgaa ggctgacttc ttgacaaatc cagacttctt tagaccctta tacatcttta
     3721 gtggtatctg gcaaggaatg ggctgggctt caacgctcta cacggcaaca ttggtaaatg
     3781 tagatccagc cttagtagaa gcagcccgac tggatggagc caatatcttc caacgaatct
     3841 ggcacattga tattccagct cttaagccta ttatggttat ccaatttgtt ttagctgcag
     3901 gtggaattat gaatgtcgga tatgaaaaag cattcttgat gcagacatcg ttaaatttgc
     3961 caacttctga aattatctcg acatatgtct ataaagttgg tcttgtatca ggagactatt
     4021 cttactcaac agcggttggt ttgtttaatg cagtgatcaa cgtagtattg cttgttgcag
     4081 ttaaccaaat cgttaaacgc atgaataatg gtgaaggaat ttaaggagga aagtatgaaa
     4141 aattcgatta tggatacaaa atttgataga cgtatcttac tcttaaataa aatcattatt
     4201 gtctttatcg ttttgatgac tttgcttcct ttactttata tcgtcgtagc atcctttatg
     4261 gatcctaagg ttctggttag tagagggatt agctttaatc cagccgattg gactgtagaa
     4321 ggttaccagc gtgtattcag tgaccaatct attctaagag gttttatcaa ttctctacta
     4381 tactcttttg gatttgcagc tttaacagta ttgctatctg tgtttacagc ttatcctctt
     4441 tctaagaaag acttggttgg acgtcgttgg attaactact tcttgattgt gactatgttc
     4501 tttggtggtg gtttagtccc aacttacttg ctcgtaaaag aattgggaat gctcaatact
     4561 ccatgggcta tcattgttcc aggtgctgtc aacgtttgga atattattct tgctagggcc
     4621 tatttccaag gattgcctga agaattagtt gaagctgctg tcattgatgg tgcaaatgat
     4681 ttacagattt tcttcaaaat catgcttcct cttgcaaaac caattatgtt tgttctcttc
     4741 ctttatgctt ttgtaggaca gtggaactca tactttgatg caatgattta tatcaaggat
     4801 ccaaacttgg aaccattgca acttgtactt cgtaaaattc tcattcagag ccaaccaggt
     4861 caagacatga ttggagcaca agcggctatg aatgaaatga aacgtttagc tgaattgatt
     4921 aaatacgcaa ctattgtcat ttccagcttg ccattgattg ttatgtatcc attcttccaa
     4981 aaatactttg ataaaggaat tatggctggt tcacttaaag gataaaaaaa gaaaaaataa
     5041 aaggagtttt ctcatgaaat tcaaaacatt ctcaaaatca gcagttttgt tgacagctag
     5101 tttagcagta cttgcagcct gtggctcaaa aaatacagct tcaagtccag attataagtt
     5161 ggaaggtgta acattcccgc ttcaagaaaa gaaaacattg aagtttatga cagccagttc
     5221 accgttatct cctaaagacc caaatgaaaa gttaattttg caacgtttgg agaaggaaac
     5281 tggcgttcat attgactgga ccaactacca atccgacttt gcagaaaaac gtaacttgga
     5341 tatttctagt ggtgatttac cagatgctat ccacaacgac ggagcttcag atgtggactt
     5401 gatgaactga gctaaaaaag gtgttattat tccagttgaa aatttgattg ataaatacat
     5461 gccaaatctt aagaaaattt tggatgagaa accagagtac aaggccttga tgacagcacc
     5521 tgatgggcac atttactcat tcccatggat tgaagagctt ggagatggta aagagtctat
     5581 tcacagcgtc aacgatatgg cttggattaa caaagattgg cttaagaaac ttggtcttga
     5641 aatgccaaaa actactgatg atttgattaa agtcctagaa gctttcaaaa acggggatcc
     5701 aaatggaaat ggagaggctg atgaaattcc attttcattt attagtggta acggaaacga
     5761 agattttaaa ttcctatttg ctgcatttgg tataggggat aacgatgatc atttagtagt
     5821 aggaaatgat ggcaaagttg atttcacagc agataacgat aactataaag aaggtgtcaa
     5881 atttatccgt caattgcaag aaaaaggctt gattgataaa gaagctttcg aacatgattg
     5941 gaatagttac attgctaaag gtcatgatca gaaatttggt gtttacttta catgggataa
     6001 gaataatgtt actggaagta acgaaagtta tgatgtttta ccagtacttg ctggaccaag
     6061 tggtcaaaaa cacgtagctc gtacaaacgg tatgggattt gcacgtgaca agatggttat
     6121 taccagtgta aacaaaaacc tagaattgac agctaaatgg attgatgcac aatacgctcc
     6181 actccaatct gtgcaaaata actggggaac ttacggagat gacaaacaac aaaacatttt
     6241 tgaattggat caagcgtcaa atagtctaaa acacttacca ctaaacggaa ctgcaccagc
     6301 agaacttcgt caaaagactg aagtaggagg accactagct attctagatt catactatgg
     6361 taaagtaaca accatgcctg atgatgccaa atggcgtttg gatcttatca aagaatatta
     6421 tgttccttac atgagcaatg acaataacta tccaagagtc tttatgacac aggaagattt
     6481 ggacaagatt gcccatatcg aagcagatat gaatgactat atctaccgta aacgtgctga
     6541 atggattgta aatggcaata ttgatactga gtgggatgat tacaagaaag aacttgaaaa
     6601 atacggactt tctgattacc tcgctattaa acaaaaatac tacgatcaat accaagcaaa
     6661 caaaaactag aggttgatta tgggagataa gaaatacaca gtagaaaaag ccaatcgttt
     6721 tatagcagaa aataaacatc tcgttaatac tcaatataag cctgaagaac atttttcagc
     6781 tgagattggt tggatcaatg atccaaatgg atttgtctat tttcgtggag aataccatct
     6841 cttttatcaa ttctatccat atgatagtgt ttgggggcct atgcactggg gacatgctaa
     6901 aagtaaggac ttggtgactt gggagcactt gccagtggca cttgctcctg accaagatta
     6961 tgaccgaaat ggttgtttct caggctctgc cattgtcaag gatgatcgcc tctggctcat
     7021 gtacactgga catatcgaag aagaaaccgg tgtccgccaa gtgcaaaata tggcattttc
     7081 agatgacggg attcactttg aaaagattga acaaaatcca gttgcaactg gatcagactt
     7141 gccagatgag ttgattgctg ctgattttcg tgatccaaaa ctctttgaaa aagatggacg
     7201 ctattactcc gtagtagctg ccaaacacaa gaataatgtg ggctgtatcg ttctactagg
     7261 gtccgataac ctagtagaat ggcagttcga atccatcttt ttaaaagggg tagaacacca
     7321 aggctttatg tgggaatgcc cagattactt cgagttagat gggaaagatt gccttattat
     7381 gtcacccatg cgttatcagc gtgagggaga ctcatatcat aacatcaact catcgctttt
     7441 gttcacgggt aaggtagatt ggggagaaaa atgttttatc ccagaatcag ttcaagaaat
     7501 tgatcatggc caagacttct atgcgcctca aacattgttg gacgatcaaa atcgtcgtat
     7561 cctgattgct tggatgcaga catgggggcg tacccttcca acccatgacc aagaacacaa
     7621 atgggcatgt gccatgactt tacctagaat tttaagattg gaagatggca aactaagaca
     7681 attccctgtt aaaaaaggcc aatatcaaat ccaaatagat aaagattgtc attaccactt
     7741 aggaaatgat atagattatc ttgaatttgg ttatgatagt aatgcgcagc aagtttacat
     7801 tgatcgtagc catcttattc aaaaaattct aggtgaagaa gaacaggaca ctagtcgacg
     7861 gtatgtagat attgaagcta aagaattgga agttgttcta gataaaaatt ccatcgagat
     7921 ttttgtcaat caaggtgaag caagcttgac tgcaacttat tacttaacgg tgccagctga
     7981 gctatcacga attgattaaa aattaagtta tttctcctaa agaaaaagtt ctctttctaa
     8041 aatagtggaa agaggacttt ttgtgttttg ggtatataag cttagtttat ggtatttgta
     8101 aaattggtgt tggattatga tttaagctag ttttctaaag aatttgaaaa aaattttatt
     8161 taagcaaaaa aaacccttgg ttccaaggct tttcctgttg tatttatatg ccccctacag
     8221 gaattgtagg agatatgttg tttagatgtt cttgattttc tggtgttttg taacgtttaa
     8281 atgagttttt tgagtttgtt ggtggggcgt tgcccggcaa ttgcccgact tattgtttga
     8341 aaaagaattt aaaatatggt atagttaatt atagattaac acttgggggg aatagatgaa
     8401 gaataatgaa agattaggta ttaaattaag tagagatagc gttttaggat tgagggaagt
     8461 tagaaggctt tatttaggca gttcagatat cccagtgcct gatgggtatg tgattgaagt
     8521 tgcttataaa cagatatcaa atgagattga tattattgat tgggtagagt tgaacaagtc
     8581 aaaaattaag ataagtgaaa ttagtgaaag cgtagatata gatgccacta gcttgagaac
     8641 aactttgact ttagacacgt tagtatatga aggtatgaga gatatacagt taaagttgag
     8701 agagcttaca aaggggagag tattcttttc atttgtagtg aagttagttt tatttgcttc
     8761 tattttaaag aaaaaaggtt tactagaaaa atttcaagaa aagtgttaat caagtattga
     8821 ctttttagtt gagttcaagt atactttaat tagagagatt tctctctaaa ttttttcgct
     8881 tcttttgtgt taatcaatga caaactcttt gtcttatttt ttaacgcttg ggtgtgttaa
     8941 tcaaagatgt atatattgga ggatgaagat gaaagctaga gcttcaccgt tgaattgatt
     9001 ttgtttctag aaaaaatcaa taattagaaa aaataagagg taagaaatga atagaaatgt
     9061 actagagttt ctgaaaacag agacagctga gaaaattagc cttttcatca ggaaaataaa
     9121 tggattagaa ggaaatgtga cattactttc tattaactct caagatttgg aagatattaa
     9181 aaatgctatg ctttccaatt ctaatctcgg attaaaaatt gcgagactgg atgtgatgaa
     9241 gaaaatagca tatgcttcta atcgtactca ttataaagat ggaacgacta tcatggatga
     9301 catctcatct ggtaaaatac atcgtcgccc taaaagctat atctaataag gaaggttaat
     9361 ccctcttcct tattagatat ttaaaaaaag gagaaaaata tgcttaagaa tttttgtcaa
     9421 aatgccttta ttagtttata tttcatagtg tctctgctag gaggattttc agctcaggtt
     9481 gacctaaaat ccttctctcc ttatcaatct atgaagatag ccttgttatt aggagttgct
     9541 ttaattttat tgcaacttcc aataatgttt gctaaattat tagaagcttt aaaaaccaag
     9601 aaaggtgaaa ctcatgaatg acatcgtaaa aatgagatta gccttttgta tcactataat
     9661 attgatggca tgctctgttt ttgtgtttac tcctgttgga gaaggcatgt ccctactttg
     9721 ctcaattttt gctaccccgt ttttatttat ttttgttttc tattttttta aaataaaatt
     9781 aagaatttta cttattatta tcaaggattt cataaaaaaa tttagatagg tataagatgt
     9841 ttaaaattaa acaaacggct tctttgtctg atcattattt tttaaataca tctaaattga
     9901 gaagtattcg ctggtttact ataggatttt tgagcatatt gtccctttct agtagtattc
     9961 tttttaaggg atggtttctt caaatgatta cattatccgt tggattgatt ataactttgt
    10021 atattgaaag aaaaatcaag ggatgggctc agcagattga accgctgtta attgtcagag
    10081 aaaaccttct atttatgctt cgcagaaatt cctttctttt tacagcaaca aaagatggcg
    10141 ctattcttcg ttcagctaga tttaattacc aattgaatga tgtttccatt gtaattcaag
    10201 cattgaaatc tggagatgaa tttacgagag agatggagac tttagaggtt ctcctatcta
    10261 gtactttggg aataagccta tcgtcaaaag aaatttatgc gactcatgtt gaatatgttt
    10321 ttgtatatag acagcctgaa cgtttacatg ttacctccct ccctcttgaa gatgatagcc
    10381 tgaaaattaa aatctatgat gattttgtta tcgatttgag aaaaaacttt tccatgctta
    10441 tatcgggggc ctccggtagt ggtaaatctt tctttacata ttattacttg actcgtttca
    10501 tatctcagac cgtaaatggg aaacatgcaa aaatatatgt gattgaccca aaattttcag
    10561 atatttataa attatgcgaa ttttctggtt ttccagtaga aaattatgga acaactaatg
    10621 aagatgcctt tagaatcgtg cgtcactata ttaacgagat gaataggcgg atggaaattt
    10681 acaacaaaag tgatctgttc aatagtattt gtatagactt gggctttcct cctttactgt
    10741 taataataga ggagtattca tcgttagtag cttcgatgga tgctaaagct aaaaaagatt
    10801 ttgaaaatat ggttgctatc gttgctcaaa aagcaaggtc tctatctatg ggggtttgta
    10861 ttgttatgca acaaccccgt tccgatagcc tttctaccaa tattagagaa cagcttgtca
    10921 atgctatatt tcttggagcc ccaactcgcg aatctagcca gatggtgttt ggcacaacag
    10981 atgtgccgaa agttcaaaaa ggcaaagggg tgggacttta ctctatagag cgagagcctc
    11041 ctaaggaatt ccattccccg atgtttgata gagatgtgtt tgagacaatt ttttcaattt
    11101 gggaatttgc ttctaaagat tatgctaaag attatatgaa ggatgaagat gtatgagaat
    11161 tttaagcgtt ttgaagatga ataaaattct tttattcatt ttcaaaatgc cattgtgcag
    11221 ccggcgaaca acaaggccgg tcggacgtaa cgtccgaata aatgtattta tgtccaatac
    11281 tgattgacgt taaaagctgt atattacttt aaataaggaa ggatttttta actatgaaag
    11341 aaactgttgt tgttctggcc atttctacga agaaagacag aggctgggta agagtttcca
    11401 cagccaataa ttgttggagt gacctaggta tgcatttcga taaatccaaa tttggagctg
    11461 ttttctctgc tccaggcctt tatgaggttg aagtgattaa taatgcttca tttggacaga
    11521 atgcccaata tgaggtgatt cagtccagaa agcttgggac ctttgcagaa ttgattgaaa
    11581 tggcaaaaat taaataattt atatttaggg taaggctgga cctgccagct ttgctggcaa
    11641 gtggagcgtg gtcagtggaa cggcagtctt accctaaaat ttaagtatat agaatgtttt
    11701 gttttttgaa ggagaaattt catgaataaa gaagttttaa atcgggctcc ttctaatagc
    11761 ccgataacga tacatcaaat gtctaataag agttactcta aatttcaaga ggaagtatct
    11821 ctgaagtatg ggtttatcgg tctgaaattg gataagctaa gtttgaccgc tgaagttagt
    11881 gaggaatttc attctgagat tcttagtggg aacttcacct tatatgatta tttcggtgta
    11941 gttgagccga atttaaatag aaatggtgaa ctagctagtt ataaagggca attctttaat
    12001 gatgaaaaag agaattggta tatcgagtat acccccgttg cgtcgattaa gatgaacaaa
    12061 agacctttaa agattgaatt tactccttca aaagtttcaa aaaagaattt tttaattgtc
    12121 tttcatagaa tgtttccgta catgtttaac atcgcaatct ctacttttca tttagcctat
    12181 gattttgagc gagatttatc tgctttacgt gtaaattggc caaaagtaat gtatcgtcct
    12241 atttataagg ggatgaaact tgagactatg gattttggtg ctcctaaagg taattatcat
    12301 ctaactgctt ataataaact taaagaacgt atggatagtg gagatatggc agaaatagaa
    12361 atttatcagc aatatgataa tctatggagg attgagtata aattctacaa tgaaggcaac
    12421 ataaaaaaag aattaaaaaa tggattacca ttcttagcta aaattccagt gtatattgaa
    12481 aatttcaaag gcttagaatt taataattta ggagttaatg agaagattta tcttttcgct
    12541 cttcgtaata aacctgaatt atttgcagaa tctgataaac gaacggtagc taagtataaa
    12601 aaacttgccg aaagtatctc tgaagttaat ttgaatgtct tttttcaaaa tgctttagat
    12661 tttgttgaaa tctttaatca agagccttgt ctgataaatt tttttgagtt tatgaattct
    12721 atgttacaag gcgatattcc aaagttaaca ataaaccaag aataataaga ggggaacagt
    12781 atgaaagata cgatttctaa taaggatttg atttccatgg gctatagacc atcaacagca
    12841 aatgctatta tccatcaggc gagagaatta cttgtatcac gaggctatac attttataat
    12901 cgcaaacgtt tgatggttgt tccaaaaggt gttgtgaaag agttgttggg aatggaattg
    12961 tgaaatggct tatatcgagt ataaacagcg tgggaagaaa aggctttggt ccttttctat
    13021 aagagaaaga agcaagagcc tactccataa aagcggattt aaaacaaaac gagaagctaa
    13081 aatagaagcg gagaaagttc ttcataagtt aaatactggg agtgtcttaa gctctagtat
    13141 gactttatcg gagctttata atgaatggct tgatttaaaa attttaccta gcaatagaag
    13201 tgtagttact aaaaaaaaat atctcatgag aaagaaggtc atcgaaaggt tatttggaaa
    13261 taagcctgta tcacaaatta agcctagcga gtatcaaaaa attatgaatg agtatggaga
    13321 gactgtatcg agaaatttct taggaagatt gaattcttgt attcgggcaa gtatacagat
    13381 ggctattgct gataaggtga taatagagga ttttactgct tatgttgagt tgttctcttc
    13441 taagagtgga caaaaggttg aggaaaagta tttgcatgct gagtcagatt atcaaaaagt
    13501 tttagtatat ttgaaaaata agtttgatta tcaaaaatct attgtaccgt atgtaattta
    13561 tttccttttt aaaactggca tgcgtttctc cgaattgatt gctctaactt gggatgaagt
    13621 tgacgagctt aatgagcaac ttaaaactta tcgtcgttac aacactgcta ttcataagtt
    13681 tactccacct aaaaacaata cttcaataag attagttcct attacttcag atatgctttc
    13741 cttgttaaaa acattgaaaa tattgcaatt aaaaacaaat aaagaattaa atattgataa
    13801 tgaaaataat ttgatttttc agcattttgg ctatgtctac gatgttccag atattgcaac
    13861 agtcaataaa gctataaaag taatgttgaa ggaattgcaa atttttccat tgattactac
    13921 caaaggagct agacacactt atggtagtta tttatggcat aataatattg atttgggagt
    13981 tatagcgaaa attttaggac ataaagatat ctccatgttg attgatgttt atgggcatac
    14041 cttggaggaa aaaattagtg aggagtttat ggctgtgaaa agtttgttgt aaaaacacgg
    14101 caaattgcac gacaattttt aaaaggaaag caaaaaaagc cctatattat aaggcttttc
    14161 ctgttgtatt tagatgcccc ctacagggat cgaacctgtg acccacggat taagagtccg
    14221 ctgctctgcc agctgagcta aggaggcaaa gaaaaaagct gtattggtgc cgaaacttca
    14281 cggtttgtat tgaacccgcg caattaagca ggtgggcaac tcgctctaac tgaagctgtt
    14341 tccgtgtgag acggcctaca tgctgttaga agacttttgt ttccctaata atacaaaaaa
    14401 tagtcggtca acacttaagt gtgaagtcgt acaccacagc gtttctatac ttatatgata
    14461 ccactttttc aaaaaaaatc aagaggaaag tgcaattttt tgaaaaggat ttcagatttt
    14521 tcgcaaacgg tcgatagctt cctttctttg agccaaagcc cgttcatatt taccagtatc
    14581 ttctgcttgg aaatagtgat gattacgaat tttttctggc agatagtctt gcttgaccca
    14641 atttccagga tagttgtgtg gatagagata gtcttgggca ttccccagtt ccttgcttcc
    14701 actgtagtgc ccatcacgta ggtgtcgcgg aataggcaag tgccctgatg ttttgaggtc
    14761 agcaagtgcc ttatccatag ctacataggc tgagttggat tttggagaaa gggccaaatc
    14821 aatcacgaca ttggcaatga gaatgcgggc ttctgggaac ccaatcttct gggcagcatc
    14881 cagagcagtc acggtatgaa tctgggcctc aggattggct aagccgatat cttcataggc
    14941 gataacagtc aagcgacgag cgagactagg cagatcccca gcctcaatca agcgggcagt
    15001 atagtggaga ctggcatcca catctgagcc acgaatagac ttttgcaggg cagatagaac
    15061 atcatagtga ccgtctccat ccttgtccat agtgatgtag cttctctgaa gactattttc
    15121 catgatgtct aaggtgatgt ggcgaatgcc ctcgtcattc tcaggggtag agagaacagc
    15181 taagtccagt gagttaaagg cagagcgaag gtctccgttt gtagaggttg cgatgaaatc
    15241 cagcgcatcc tcatctagtt ctattggaaa atcaaaacca cgttcagggt tacttagagc
    15301 tatctgcagg gcctctttga cgtcttggtt agacagaggt tccaactcga aaatttgaac
    15361 tcggctacga atggcaggag tgacagagaa gaaaggattt tcagtcgttg ctccaatcat
    15421 gatgaccagt ccactttcca agagaggcaa gaggaagtct tgcttggtct tatctagtcg
    15481 atgaatttcg tctagcaata ggacgagacc accagaaaat ttagcttctt ccgagatttc
    15541 ttgcagtcgc tttttactat caactgtcgc attgaaagtt cgaaaggcat acttggtcgt
    15601 tccagcgatg gcagaggcaa tactggtttt gccgattcca ggagggccat atagaatcat
    15661 ggaggacagg cggttggctt ccaccatgcg gcggatgatt tttccaggtc cgaccagatg
    15721 ctcctgaccg atgacctggt cgatggtttt agggcgcatg cgaagcgcga gattgtctgg
    15781 catagcagtc ctttctagcg tggatttgag tagaatgact catctactat atcttactat
    15841 gtccattcta gcctattagt tgtgatattt caatggtttt gtaataatca gggagtgaga
    15901 tagaatcttt tttactattt aatttaatga ggagaggtat cagcatgaga gatttgattt
    15961 tccttaaagc tcaaaatagg atagttgagc ctaaagaagt ggaagtgctg acttgagaaa
    16021 taatattgct gaatgtcatt gtatgaacta taatgaaaag agaggtgata agcaatggaa
    16081 atgatggacc aagtcaggaa attttgattt ttacaaaaca aattcgtcat tggattctta
    16141 gtgatcaagt tatttcaggg aaaagaaaac ttttcttccg ggaagatact ccaaaagaga
    16201 ttttagattt gtacgaaaac attaaatcta aacttgattt tgcttaccaa taagtttatt
    16261 ctaataatgg gttgaaaaaa tatgaaaaat agaataattg atgtttttga agtagtaaat
    16321 cgcatccttg taataactgt tgaaaatcct gatttcgaag acttgagagt taatcatact
    16381 caatgaaaat caaagagcaa actaggaaac tagccgcagg ctgtacttga gtacggtaag
    16441 gcgacgttga cgtggtttga atttgatttt cgaagagtat cagtttgtaa aaattggaga
    16501 taaaaaatat agagtacgca gtgttcctat gattcattca actccgcctc aatctgtctt
    16561 agatcgagat acttttacaa ttgactatac agatgatgaa ttgctcgata aagaagcagt
    16621 ttttactact cattagaaaa ataggtctga ataaattggc ttcccttaga accacatcta
    16681 ggggctttta tgtataatag aataataagt atcactcctt tacaatacgt gtaacacgtg
    16741 ttataatggt gttgtcagga ggtaaaagcg ctatgcctat gacacaaaaa gagatggtta
    16801 aactccttac ggcccatggt tggataaaga ctagaggcgg taaaggctcc catattaaaa
    16861 tggagaagca aggggaaaga cttatcacaa tccctcatgg tgagctgaat aagtacactg
    16921 aaagagggat aagaaagcaa gctgggttgt aaaattcagc ccctgttttt tgatatggag
    16981 gtagtgaaat gttagttacg tatccagctt tattttatta tgacgacaca gacggaacag
    17041 aagcgactta ttttgtccat ttcccagatt ttgaatactc agctacacaa ggagagggga
    17101 tttctgaggc tttggctatg gggtcggagt ggctagggat aactgttgca gatttgatag
    17161 agagtgatgg agagttacct cagccatcag atatcaatag cttgtcttta attgataatg
    17221 atccttttaa agatgatgaa gatttcgtgt caacctatga ccttgataaa tcttttattt
    17281 ctatggtatc tgttgatgta tcagaatacc taggaagtca ggaacccata aaaaagactt
    17341 tgaccatacc aaaatgggca gataagttgg gacgagaaat gggacttaac ttttctcaga
    17401 ctttgacaga cgctattgca gataagaaag ttcaagccta agattaagcg tggtatcgtg
    17461 gtaatagtca ataaaaaagc acgtccactt gtgctagtta ctcgcctatt gattttatag
    17521 atttattagc cctttcgcgg gctttttata ttgattttta tgagaaatga agaaatcaga
    17581 cttttaagaa aatcactgat accaagggtt taaatgaggt aatatggtat aattaggaca
    17641 taaaataatt ttgtggtaag atggtagtat ctattttagc atatttccga gcaatcgggg
    17701 cgattaaaga gtcgcataga aagaggacaa aatggcaaca tacggatttt tagatgtttt
    17761 agaggaagag ttggacaaga actttccctt tgactttgag attagctggg acaaacgcaa
    17821 ccatgcggta gaagtgagtt ttctattgga agcgcaaaat gctgcaggtg tggagatggt
    17881 ggatgaagac ggagaggttt tatcagatga cattcttttt gaggaagcgg tccttttcta
    17941 caatcctgcc aagtcaacag tcaatgagga agactatttg actgttattc cttacctgcc
    18001 taaaaaagga ttttcccgtg aatttttagc ttattttgcg cttttcctta aagatactgc
    18061 tgaggttggg ctagatgtcc tcatggactt tttggaagac ccagaagcag aggaatttgt
    18121 catggaatgg aaccaagaag tctttgaaga aggaaaagtt ggcttggaag agggagaatt
    18181 ttatccttat ccaagatact aggagttggt tggaggtgtt atgaagaaaa ttgggactta
    18241 tttggtttat gtgctagctt ttgtctttat tatgctagct tttgcttgtg gaacaatcgc
    18301 atttgcagag ttggggtatt ccgcagtttt agcctttact tttggttatg ccttcgctct
    18361 tctaagcatg tatttaatct ttattcttca tgagctgggt catgcttttt gtggctactt
    18421 gacaggctat cggctggtgg cttttggatt aggacatttt attttgacca aaaagtcagg
    18481 caggtttcat cttagtagaa cagccattct gaaaaatgtt ggtgctcaat acattggttt
    18541 aaaagaggat gaaagcgatc aaagaatcat cctgatgctt tcaggaggct tgatggttca
    18601 tctcggcttg atattattgg cgatagtgtt tggatttttg acaagaagct ggtattttgc
    18661 agggacttgg atttttctta atttatcttt cttcctaaat aacattttac cagtcggcat
    18721 caccgatgga gcaaaaattt gggaattact acaacaccct gaaaatacca aatacgccta
    18781 cctggtattg agacattctg ctcaaacttt gctggctcct caagaatatg atttgaaaga
    18841 ctttgttcaa gcagttcctg aggatgcacg agggagtttt gcggatggtg tattaggtat
    18901 gcaaggtgaa gtttccattt tggaagggaa ggaagaagta gctaaacagc agtttcaagc
    18961 attacttgag aggacaacta ctccgatgat gcagacagtt gcccaactat ccctacttca
    19021 tatcgccttg ttggaaggag attttgagca agcggagcaa tatgctagta ttcgacaggt
    19081 caaatcgttt ctgtctctca aactgtccaa tcttcaagtg atacaagcct ggtatcaatt
    19141 aaaggtgaag aaagatgtag atcgaactcg taaggctctc aagattgcta gacagaaaat
    19201 ggatagtagt cgaatgttga gggacgagaa acgctattat gaaaacttgt tagcagagct
    19261 ggaaaaggaa ttagccgaag gagtctaata tggaaataga gatttctgat ttcacaggtt
    19321 gcaagattgc tttgttttgt ggggataagc tactgacgat tttgcgtgat gacaaggacg
    19381 atatcccttg tcccaacatg tgggagttgt caggtggtgg ccgtgaaggg gacgaaagcc
    19441 cttttgaatg cgctcggcgt gaagtttatg aggaactggg aattcattta gatgaagact
    19501 gtctgctttg gagcaagatt tatcctagtg taatttttaa aggcaagaaa tcggtcttta
    19561 tggttggtca gctaagacaa gaacaatttg acaatatcat cttcggagat gaaggacagg
    19621 gctatcagct gatgaatgtt gaggaatttc ttagttccag tcaagttgtg cctcagttgc
    19681 aagagagatt aaaagattat ttaaaagtaa gtgattagaa aggatggttc agttaaattt
    19741 ctaaactgaa cccgccctaa acactgtgcc aaaaagataa acttctctta gacacaagcg
    19801 tcttcagaga atttcctatt ttggttttgt gttttacggg cttggtatct taatgatgga
    19861 aacatggcaa gagttaaaag ttacagtgaa gcgtgaggga gaggagttgg tttccaatct
    19921 cttgattgag ctgggagcgc aaggtgttgc gattgaagac agtatggact atgtgggaaa
    19981 tgttgaccgc ttcggcgaga ttttcccaga ggtcgagcag caagaagaaa tcgtagtgac
    20041 agcctactac cctgacacgg tggatgtgac agtggttgag gcggacttgc aggctcgcat
    20101 atcagaattg acggatttta tggatttggg agagttaaaa ataggtacga ctgccttggc
    20161 tgaggaagac tgggcagata actggaagaa atactatgag ccagctcgta tcactcatga
    20221 tttgaccatc gttccctctt ggacagacta tgaggcgact gcgggagaaa aaattatcaa
    20281 gctggatcct ggcatggctt ttggtacggg aacccaccca actaccaaga tgagcatttt
    20341 tgccttggaa caggttcttc gtggtggcga aacggtgcta gatgtgggaa ctggttcagg
    20401 ggttctctct attgccagct cgcttctggg ggctaaagaa attttcgcct atgacctgga
    20461 tgatgtggca gttcgtgtgg ctcaggaaaa tattgagctc aaccctggaa tggaaaatat
    20521 ccatgtagcg gcaggcgatt tgcttaaagg cgtggagatt gaagcagatg tcatcgtggc
    20581 aaacatcttg gcggatatcc tcattcatct gacagaggat gcttatcgct tggttaagga
    20641 tgaaggttac ctgatcatga gtggcattat caaggataag tgggacatgg tgcgcgagtt
    20701 ggctgaatca gctggatttt tcctcgaaac tcacatggtt caaggggaat ggaatgcctg
    20761 tgtctttaag aaaaccaagg atatctctgg tgtgattgga ggctagcatg cagcagtatt
    20821 ttgtaaaagg cagtgctatc tctcctgtca ctatcgagaa caaggaaacc agtaagcata
    20881 tgtttcaggt tatgcgcttg aaagaagagg atgaggttac cttagtcttt gatgatggca
    20941 tcaagcgctt ggcgcgcgtg ctggatatgg aaaatcgtca gtttgagttg gtccaagaat
    21001 taaatgacaa tgtggaacta ccagttcaag tgaccatcgc atctggattt cccaagggag
    21061 acaagctgga gttcatcgct caaaaagtaa ccgaactggg tgctagccaa atctgggcct
    21121 ttcctgcaga ctggtcagtt gccaagtggg atggcaagaa attgggtaaa aaagttgaaa
    21181 aactagaaaa aattgccctt ggagcagccg agcaaagcaa gcgtaatatt gtaccaagta
    21241 ttaaactttt cgagaaaaaa gcagattttc taactcagct ggaccagttt gactctatca
    21301 tagtagccta tgaagaatca ggtaaagaag gagaagccgc tgcgcttctg caagcagtca
    21361 ctggtcttga aacaggagcc aaactgctct ttatctttgg tccagaaggc ggtctctcac
    21421 ctgcagaaat cgaaagtttt gaagctaagg gagccgtttt ggtaggccta ggtcctcgta
    21481 ttttgcgagc agaaacagca ccgctttacg ccttatcagc ccttagtgtt ttagtagaat
    21541 tagagaaata agaggaagaa aatggaacaa aaacaccgtt cagaatttcc agagaaggaa
    21601 ctctgggact taacagccct ataccaagac cgtgaggatt tcttgcgtgc aatcgagaaa
    21661 gctcgtgaag acatcaacca atttagccgt gactacaagg gtaatcttca tacttttgag
    21721 gatttcgaga aggcctttgc ggaattggaa cagatctaca ttcagatgag ccatattggc
    21781 aactatgctt ttatgcctca gacgacggac tatagcaatg acgaatttgc caatattgcc
    21841 caagctggga tggaatttga aacagatgcc agcgtagcct tgaccttctt tgacgatgcc
    21901 ttggtggtag cagacgagga agtcttggac cgtttgggtg aattgcctca cttgacggca
    21961 gctattcgtc aggccaaaat caaaaaagcc cactatctag gggctgatgt ggagaaggcc
    22021 ttgaccaatc tcggtgaagt tttctatagt ccgcaggaca tttatactaa gatgcgagct
    22081 ggggattttg aaatggctga ctttgaagcc catggcaaga cctataaaaa cagctttgtc
    22141 acctatgaga atttctacca aaatcacgag gatgctgagg ttcgtgagaa atccttccgt
    22201 tccttctcag agggacttcg taagcaccaa aatacggctg cagcagccta tctggctcag
    22261 gtcaagtctg aaaaactctt ggctgatatg aagggatacg actctgtctt tgactatctt
    22321 ctagctgaac aagaagtgga ccgtgtcatg tttgaccgcc agattgacct catcatgaag
    22381 gactttgcac cagtcgctca gagatacctc aagcatgttg ccaaggtaaa tggtcttgaa
    22441 aagatgacct ttgcagactg gaaattggac ttggacagcg ccctgaatcc tgaagtgact
    22501 attgacgatg cctatgattt ggtcatgaag tcggtagaac ctttggggca agaatattgt
    22561 caggaagttg ctcgttacca agaagagcgc tgggtggact ttgctgctaa cagtggcaag
    22621 gattccggtg gttatgcggc ggacccatat cgcgtacacc cttatgtcct catgagctgg
    22681 acaggccgtt tgagcgatgt ctataccttg attcatgaaa tcgggcattc tggtcaattc
    22741 atcttttcag acaatcatca aagttacttc aatgcccata tgtcgaccta ctatgttgaa
    22801 gcaccgtcaa ccttcaatga attgctactc agtgattact tagagaacca atctaatgac
    22861 ccacgtcaaa aacgctttgc tctggctcat cgcttgacag acacctactt ccataacttt
    22921 atcacccacc tcttggaagc cgccttccag cgtaaggtgt atacattgat tgaagaagga
    22981 gaaaccttcg gagcaagcaa actcaacagt attatgaagg aagttttgac agatttttgg
    23041 ggcgatgcca ttgaaatcga cgacgatgca gctttgactt ggatgcgcca agctcactac
    23101 tatatgggct tgtatagtta cacttactct gctggtcttg tcatctcgac agctggttac
    23161 cttcatctta aaaactcaga aactggagct gaagactggc tcaatctcct caaatcaggt
    23221 ggtagcaaga caccacttga gtcagccatg attatcggtg ctgatatttc aacagacaaa
    23281 ccactccgtg ataccatcca attcttgtct gacacagttg accagattat cgcctacagt
    23341 gctgagttgg gggagtaagg ggaatagaaa aattttttag aatgatgttt atgggcttgt
    23401 taagcgtcat tctatttgtc ttagttgtag ctattttcaa aaatgtcgtt gaaggtcgtg
    23461 atgttaaatt tgaacttact gtagaactgg tattgatagt tatttacgtc attttatatc
    23521 agattgtatt taattgagaa ttcaatattg agtcatttaa gactgccttt ttgaacagtt
    23581 gctagaaatg tagaggtatt gaccatgtat caagatttac taagaaaaat agcagaagaa
    23641 aaaccaaatt ataaccagga ggaaatccag tggttgcttg atcatttggg agatccttct
    23701 ccagaaattc gcgatgacct tgtttttaca agctttgcta gagggattca ggaagagcta
    23761 tttacacagg agcaatttca tttcattgct gaaggggttt catctgatgt aggactagat
    23821 aaagagattg ataaggtagg tctgccaaca cttgaacgtt cttttagggc acttgtttat
    23881 gcaaatctct tgtatgcaga tgccaaccag caatcggttt tttatcaggg attacaatta
    23941 gaaattcgta atgtcttttc aaatcaaggc ttgcactatc tttcaaaaga aaaggataca
    24001 acaggtttct caagtcagta tggttgggtt catgcttttg cacatggagc cgatttactg
    24061 acagaggtgg tctgtcatcc agactttcct ataaacagaa ttcatgaagt atttgacata
    24121 cttggccaac tatttaaaag aatgtcgatt cgctttacag atgatgagga ttggcgttta
    24181 gcaagagtga tctatgaacc tattttacaa gggaagttgg agcaagaaca agtagcttct
    24241 tggataaaaa ctgttgattt tccgatagaa gaaagggagg atttttccaa attttccaac
    24301 tttagatcct gtctggtgga agtctatgtc caacttgacc agagaaatag tttacaagat
    24361 gagttgaaag aagctatcca gtcttttcaa tactagagat tagctaatag ttctatgatt
    24421 ttcaaaaaat ttccaatcaa ttttcttgaa accctttcct acttttgata gactagtatc
    24481 tagtttttga aaaaaggaga aagaaaatga aaaaatttgt tgctgagtta atcggtacgt
    24541 tcatgcttgt gttcgttggg acaggagctg ttgtttttgg aaatggtttt gatggccttg
    24601 gtcaccttgg aatcgccttt gcctttggtt tggcaatcgt ggtggcagcc tactcaatcg
    24661 gaactgtttc aggtgctcac ttgaacccgg ctgtttcgat tgctatgttt gtaaacaaac
    24721 gtttgtcatc ttcagaactt gtaaactaca tccttggtca ggttgttgga gctttcatcg
    24781 cttctggcgc tgtcttcttc ctcttggcta actcaggtat gtcaactgct agtcttggtg
    24841 aaaatgcctt ggcaaacggt gtcactgtct ttggtggttt cttgtttgaa gtcatcgcaa
    24901 ctttcttgtt tgtattggtt atcatgactg tgacttcaga aagcaagggc aatggcccga
    24961 ttgctggttt ggtaatcggt ttgtcattga tggcgatgat tcttgtcgga ttgaagatta
    25021 ctggactttc agtaaaccca gctcgtagct tggcaccagc tgtcttggta ggcggcgcag
    25081 cccttcaaca agtttggatt ttcatccttg caccaatcgc tggtggagtt cttgcagccc
    25141 ttgttgcaaa aaatttcctt ggaacagaag aataattgaa actcaaaaag ccttgctcct
    25201 catcttgagg aacagggctt tttcgtatga tactcttcga aaatctcttc aaaccacgtc
    25261 agcttcacct tgtcgtaggt atggtt
//
LOCUS       DBERPV010000028        25030 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.28, whole genome shotgun sequence.
ACCESSION   DBERPV010000028 DBERPV010000000
VERSION     DBERPV010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 25030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25030
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.28"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(1..270)
                     /locus_tag="ACL8C7_001467"
                     /pseudo
     CDS             complement(1..270)
                     /locus_tag="ACL8C7_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(332..781)
                     /locus_tag="ACL8C7_001468"
     CDS             complement(332..781)
                     /locus_tag="ACL8C7_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGS1395644.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(783..1541)
                     /locus_tag="ACL8C7_001469"
     CDS             complement(783..1541)
                     /locus_tag="ACL8C7_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGS1395645.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(1656..3635)
                     /gene="stkP"
                     /locus_tag="ACL8C7_001470"
     CDS             complement(1656..3635)
                     /gene="stkP"
                     /locus_tag="ACL8C7_001470"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine-protein kinase StkP"
                     /protein_id="HGS1395646.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(3632..4372)
                     /locus_tag="ACL8C7_001471"
     CDS             complement(3632..4372)
                     /locus_tag="ACL8C7_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HGS1395647.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDEE"
     gene            complement(4387..5700)
                     /gene="rsmB"
                     /locus_tag="ACL8C7_001472"
     CDS             complement(4387..5700)
                     /gene="rsmB"
                     /locus_tag="ACL8C7_001472"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HGS1395648.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLLAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVADRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(5693..6628)
                     /gene="fmt"
                     /locus_tag="ACL8C7_001473"
     CDS             complement(5693..6628)
                     /gene="fmt"
                     /locus_tag="ACL8C7_001473"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HGS1395649.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELIKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGALFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMEIASFLNGVGRTLTVGERFGD"
     gene            complement(6641..9037)
                     /locus_tag="ACL8C7_001474"
     CDS             complement(6641..9037)
                     /locus_tag="ACL8C7_001474"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HGS1395650.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQINFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QESNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMDCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNPQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(9103..9417)
                     /gene="rpoZ"
                     /locus_tag="ACL8C7_001475"
     CDS             complement(9103..9417)
                     /gene="rpoZ"
                     /locus_tag="ACL8C7_001475"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HGS1395651.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(9442..10068)
                     /gene="gmk"
                     /locus_tag="ACL8C7_001476"
     CDS             complement(9442..10068)
                     /gene="gmk"
                     /locus_tag="ACL8C7_001476"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HGS1395652.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(10198..11811)
                     /locus_tag="ACL8C7_001477"
     CDS             complement(10198..11811)
                     /locus_tag="ACL8C7_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HGS1395653.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEIKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(12002..12256)
                     /locus_tag="ACL8C7_001478"
     CDS             complement(12002..12256)
                     /locus_tag="ACL8C7_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HGS1395654.1"
                     /translation="MLLKFTEDAWADYCYWQNQDKKTLKRINKLIKDIQRDPFTGIGK
                     PEPLKYDYQGAWSRRIDAENRLIYMMDGDSVAFLSFKDHY"
     gene            complement(12260..12514)
                     /locus_tag="ACL8C7_001479"
     CDS             complement(12260..12514)
                     /locus_tag="ACL8C7_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HGS1395655.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSTQVHVIEE"
     gene            complement(12752..13849)
                     /locus_tag="ACL8C7_001480"
     CDS             complement(12752..13849)
                     /locus_tag="ACL8C7_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HGS1395656.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILARLGIDSLAFGTEEVLD
                     YQKIADLYTEQGAEMENFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGYNIKLHPIQRQGAGYHSVDKDVNFASATALRQHQRDKDFLERFMPSVALFEQA
                     SKVSWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQVRESNLPEAIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            complement(13859..14599)
                     /locus_tag="ACL8C7_001481"
     CDS             complement(13859..14599)
                     /locus_tag="ACL8C7_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGS1395657.1"
                     /translation="MATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLELA
                     CGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGKYD
                     FVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHENA
                     EDFSMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQAG
                     FKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(14708..15061)
                     /gene="rsfS"
                     /locus_tag="ACL8C7_001482"
     CDS             complement(14708..15061)
                     /gene="rsfS"
                     /locus_tag="ACL8C7_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HGS1395658.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(15074..15574)
                     /locus_tag="ACL8C7_001483"
     CDS             complement(15074..15574)
                     /locus_tag="ACL8C7_001483"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGS1395659.1"
                     /translation="MKMAFIIIDVQNILVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            complement(15575..16168)
                     /gene="yqeK"
                     /locus_tag="ACL8C7_001484"
     CDS             complement(15575..16168)
                     /gene="yqeK"
                     /locus_tag="ACL8C7_001484"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HGS1395660.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDFDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            complement(16168..16797)
                     /locus_tag="ACL8C7_001485"
     CDS             complement(16168..16797)
                     /locus_tag="ACL8C7_001485"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HGS1395661.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEQHPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(16849..17160)
                     /gene="yhbY"
                     /locus_tag="ACL8C7_001486"
     CDS             complement(16849..17160)
                     /gene="yhbY"
                     /locus_tag="ACL8C7_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HGS1395662.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(17374..18480)
                     /gene="yqeH"
                     /locus_tag="ACL8C7_001487"
     CDS             complement(17374..18480)
                     /gene="yqeH"
                     /locus_tag="ACL8C7_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HGS1395663.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            complement(18483..19010)
                     /locus_tag="ACL8C7_001488"
     CDS             complement(18483..19010)
                     /locus_tag="ACL8C7_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HGS1395664.1"
                     /translation="MAIENYIPDFAVEAVYDLTVPSLQAQGIKAVLVDLDNTLIAWNN
                     PDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVEKFGIDYVYWALKPFTFGIDRA
                     MKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKPLVQHDSIKTQINRTRERRVMR
                     KITEKYGPITYKKGI"
     gene            complement(19025..19933)
                     /locus_tag="ACL8C7_001489"
     CDS             complement(19025..19933)
                     /locus_tag="ACL8C7_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGS1395665.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(19990..20550)
                     /locus_tag="ACL8C7_001490"
     CDS             complement(19990..20550)
                     /locus_tag="ACL8C7_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel domain-containing
                     protein"
                     /protein_id="HGS1395666.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            20688..21897
                     /gene="sstT"
                     /locus_tag="ACL8C7_001491"
                     /pseudo
     CDS             20688..21897
                     /gene="sstT"
                     /locus_tag="ACL8C7_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            21965..22918
                     /locus_tag="ACL8C7_001492"
     CDS             21965..22918
                     /locus_tag="ACL8C7_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HGS1395667.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            23061..23441
                     /locus_tag="ACL8C7_001493"
     CDS             23061..23441
                     /locus_tag="ACL8C7_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGS1395668.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            23540..23761
                     /locus_tag="ACL8C7_001494"
     CDS             23540..23761
                     /locus_tag="ACL8C7_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HGS1395669.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            23778..24092
                     /gene="trxA"
                     /locus_tag="ACL8C7_001495"
     CDS             23778..24092
                     /gene="trxA"
                     /locus_tag="ACL8C7_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HGS1395670.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            24398..24931
                     /gene="queF"
                     /locus_tag="ACL8C7_001496"
     CDS             24398..24931
                     /gene="queF"
                     /locus_tag="ACL8C7_001496"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033739 - preQ1 synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046857 - oxidoreductase activity, acting
                     on other nitrogenous compounds as donors, with NAD or NADP
                     as acceptor [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preQ(1) synthase"
                     /protein_id="HGS1395671.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDKR"
BASE COUNT         6788 a         5847 c         4953 g         7442 t
ORIGIN      
        1 ctcccttgac ttgtgacaat cgcttgagcc ttcatagcgt ggcatttctt tttaccagaa
       61 taattcgcta attgtttttt agggcgattg atttttactt ccgtcacatc aatcattacc
      121 atgtcctcag aactgagagg agttcttgaa attgtaacac cacctttgaa caagagttac
      181 ttcaacccat tggctccgac ggagtaagtt gctttcgtgg ataccaaaat cagccgcaat
      241 ttcttcataa gtgcggtatt ctcgcacata tagaaagcgt tgttaattta tttatctcat
      301 ttttcagaaa attcttttat ttctgtaaag tctacgatac tcgatgtgtt tttatataat
      361 gatacagtct gagaatcact gttccgctag ccattccaat agagattacc aaagccaaca
      421 tgacaaccaa ggtcgcactt gccagtgctt tattatagtc ccctgtcaca aaaaaggcag
      481 ttgttcggta ggagagataa cctggaacca gcggtgccaa aatggccaag ataaagacca
      541 cagcaggtgt cttataaaga atacttaaaa tctggctgac acaagaacca ataatggctg
      601 caatgaaggt agctacaatg acattggtcg gttccttgag caagagatag attagccaga
      661 cagtcatgcc caaaatccct ccaggtaaga gcatagaccg ttgcacattg agtacgatta
      721 aaaaagtgat aatggcaaga aaacttgcta ctgcttgtaa taaaaaggtt gttagtgtca
      781 tattagttca tcaataccaa ggcgacagaa gttcctgccc ctaaagcgag ggtaatgagc
      841 agggattcaa acatcttact cataccagag tttatgtggt tggtcataat atcacggacc
      901 gcattggtca aggcaatacc tggtacaaac ggcatgaccg caccagctat aatcaaatct
      961 gccgttgaag gaaaacctgt gtagcgagcc caaaactggg caattatccc aaagacaaag
     1021 gctccagcaa aggctgtcac aaagggaatt cggataaatt tttccacata gagggaaaag
     1081 gcaaaaccaa ataaggtcgc cactcctgcc ccaagtgcgt cgtagatatt tccgctaaac
     1141 ataactgaaa agaaaggagc actaaaggtc gcagccagag ttacctgcaa cttagtatag
     1201 ggaaggggtt gagcttgcaa ggccgtcaat tgcttaaagg ctgtttctaa gtcaatctgc
     1261 cccccaacta gctgacgaga aatctggttc acatcgcaga ctttttcgat gttataagaa
     1321 gaggaggtca cgcgcttcat gcgcgaaata ttggtatttt caatagagaa aaagatagcg
     1381 gcaggcatgg caaggacatt gcaatccaca atcccctgcg aatgcgcgat tcgaatcatg
     1441 gtatcttcta cacgatggat ttctgagcca cttttaagga gaatagtccc cgctagcata
     1501 atcacatcaa tgacggcatt taattctttt gattcttcca tgctttcctc cttttatcaa
     1561 ctccctctat tctatcacaa atctggactc aaaaaaaatc tttgccatga aatcatgaca
     1621 aagattgatt actcattttg attatccatc tgcttttaag gagtagctga agttgtttta
     1681 ggtttgtaga ttgaaatctt gactctagtc ttattgaggt ctaccttttc acctgctcta
     1741 ggactttgtt caacaaccat gccttctgca ctacctgcag gcgctgtcgt cacttctaca
     1801 acttctatat tagcttcctt aatcccaaca atttgaatca aattgttctt agtaaactcc
     1861 aagctggaac caatgtaact cggcatggca acacttgtaa cttttttagc tactgtcaag
     1921 acaatttgag taggtttact cacatcataa gtcgttccgg cacctggact ttgtttcata
     1981 atcgttcctg gttcactttc gctggactct tcttcctcta tcttaatcaa attctcagga
     2041 accttcttct gcttgagttc tgagattact tctgtagagt tccgtccaat atagttccct
     2101 aattgaattg tcgtagcttt tttagctact gtcaaaacaa tttgagttgc cttgctcaag
     2161 tcataggtcg taccttctgg tagactttgc ttcaggaccg ttccagcctc actctcattg
     2221 gactcttctt cctcaatttt aatcaaatta tctggaactt ttttctcttt taattccgcg
     2281 ataacatcag aagatttccg gccgacataa ttactaattt ggaaggattg tttgcctgat
     2341 gagacaacca aattgatttt cgttccttct tttcgaccag ttccagcgcc aggatctgta
     2401 cggataatcc gcccttcttc caccttttca ctagcctctg tcttctcctc accaatctca
     2461 aaattggctt ttttgagcgt tgccttggcc tctgcaactg tctgacctgc cacatctgga
     2521 atggcaatgg ttgcaggagt tctggatagt atccaaataa gagaagctgc caccaataca
     2581 aggctggcca acaaaatcag gtaacgcatc ttaaatctat gttttttcgg tgcttgtggt
     2641 tggtaagttt cctctgtcac agcctggctt gggtttttga ttgatttgtg ttctgtctgc
     2701 gcttgaacct taggaataga tgtcaaggta ctctgagaaa ccttcggcaa ggtcttggta
     2761 tctgccttgc tcgtttcatc aaagattaac ttactttcat ttctacgatt gtaggacaag
     2821 ctactagaca agtccacata catctctgaa accgagcggt agcgattggt caacttttta
     2881 gcagttgcct tgataataac attttctaaa gcctgaggta cagatggatt ttctgcaata
     2941 acggacggca ggggtttctg gaaatgctgg agggcaatgg tcaccgcgct atccccgtca
     3001 taagggatat ggcctgtcaa catctcatag aaaataatcc ccatggcata gatatcactc
     3061 tgcacagtcg ccttagaacc acgcgcctgc tctggtgaca agtaatgaac tgagcccaac
     3121 atcgagttag tctgggtcag acttgtctct gcaaaggcta cagcaatccc aaagtctgtg
     3181 accttggccg tcccatctgg tgtcaaaagg atattttgag gtttcaagtc cctgtgaaca
     3241 attcctcgag tatgggccaa gcgcatagcc aagagaattt gtcccatgat acggactgct
     3301 tcttcattag aaagaggata atgttccttg atatagcgtt tgaggtccag tccagccaca
     3361 tactccatag ctaggtactg ttgaccgtct tcctcaccaa tatctgttat ccgaacgata
     3421 tgaggatggt ctagatctgc catagctctc gcttcacgct gaaaacgagc tacagctatc
     3481 gggtccgtct ggtagttggt cctcagaacc ttcactgcca cttcttcccc atctaagatt
     3541 aagtctttgg ctaggtagac atccgccatg cctcctcgac caatctgttt gacaatccga
     3601 tagcgtccgg caaaaatctt gccgatttgg atcattcttc atcctcctcg ttcatagaaa
     3661 caagggcaac cgtaatgttg tctaaacctc ctgcattgtt agcaaaacga acaagtgtct
     3721 ccgttttatc tgctaaagga atatcactgg ttacaatatc acgaatctca ctgcctgaaa
     3781 tcatgttggt caagccgtca ctattgagca agagatagtc acctgactca aggataactg
     3841 tcccaaaatc aggctgaatt tcatcttttt gcccaataga ctgggtgata atattttttt
     3901 gcggatgagc ttctgcctct tctggtgtca attgaccagc cttgagcaat tcattaacca
     3961 aggaatgatc gctcgtcaac tgatggtatt cttctccacg aatcaagccg atacgcgaat
     4021 caccaatatg agcatagata gcctgattat caataatagc aaggacttcc aaagtagttc
     4081 ccatgcctct gtaagcttca tcctgaccaa gctggtgaat cttttgattt tcaatttcta
     4141 ggtaatgggc gaaccattca cgcacttcat tgactgtatc gatctgggta tcaacccaag
     4201 ctacacccag gtctgtgacc gccatttcac tagcgatatt ccctgcacga tgacctccca
     4261 tcccatcagc taaaataatc atggtacgtc cagctctatt gacatagtgg ttgacatagt
     4321 cttggttatt tgttcgtttc tgaccaacat ctgttaataa tgaaatttcc atgtgtcagt
     4381 tccttcctaa tccgatatct tgcgaaattg actgatgaag aatccatcac ttccatacaa
     4441 ttcaggtgta atgaggatac agccgtcttt catgatatcc ttacattcat gttctagttt
     4501 tacctgctcg aactcgggat gactctctaa aaaggcctta acgacttgaa aattctcctc
     4561 tgagacgata gtgcaggtgc tataagttat tataccacct ttgcctagta tttgacaaac
     4621 actacctaat atttctaact gaatttcctg caaggacgcg aaatctgccg tttctttatt
     4681 gtatttgata tctggttttc ggcgcaaaag accgattcct gaacaaggag catccaccaa
     4741 aatcttatca aaggaatcct ggtcaaaaaa ctcatgcacc tttctggcat ccaatttttg
     4801 agtttgaacc cgatctgcaa ctcccagacg ttgggcattt tcttgaatta aatccaactt
     4861 gtggtcgtac aagtccagag cagtaacctg acctgtcgta agataagagg ctatatgggc
     4921 tgttttccca cctggagccg cacaggcatc aagcactcgc tcatcacctt gtaaatcaag
     4981 cgtcggagca accaactgac tggactcgtc ttggatggta atggctccat ccgcaaacaa
     5041 attatgccct gcaaaatgcc cctgctcctt aaccagacca gtggttgcta aaagggaatt
     5101 attcgcctcc aacaaggctt ggatttcctc ttttcgactt aggtctgtta cacgaatact
     5161 ggctttgttt cgcactaaca ggctttcaaa gatggctttt gctctctcct ctccgtattc
     5221 ttccttgagt ttggcaacta gccaaactgg gagagaatag gcaatggagt cacgcttgtt
     5281 ttttcgcttg atgctagcaa tatctggcca gccttcacgc aagatacggc gaaggacagc
     5341 gttgaccaat ttttcactgc cttttttacg gagtttggcc aattccactg cttcattaac
     5401 cacagcatga tctggaatct tgtccaaata gcggagttgg taggcactca tgagaagaag
     5461 gacatagagc cagctgtcta actggtctct gtcttcgata aagtgggata ggtaccattc
     5521 cagagtcagt ttacgggcta ccgttccata gaccagctcg gtcactaagc ccttgtctgc
     5581 tgccaaaagt tgacttccct ttagatgctt atttaaggcg atatttgaat atgcttggtt
     5641 cacaaaaaca tcctctagca ctgctagagc taaacttcta gccgtttcta ctttagtcac
     5701 caaatcgttc tcctacagtc aatgtacgtc caactccgtt gaggaaggaa gcaatctcca
     5761 tcttaggctt accagctggc tgcacttgtt tgagggatag agccccttca gccgttgcga
     5821 caatcaattc tttcttgccg atagagagaa tctcacctgg atttccctga ccttctactg
     5881 gtagggcttc ataaatctta aagcggtcgc ccttaaggaa agtatgggca acaggccagg
     5941 ggttcattcc acgaatttgg ttaaagagtt gacgattggt tttgttccag tccagttttt
     6001 cttcctctgg ctttatattt ggagagaagg taacctgact cgtatcctgc ggttcaggtt
     6061 tgatatcacc agcaatatag gcaggcagag tgtccaaaag caaatcacga ccaactagcg
     6121 ccaatttttc aaacaaggcg ccaacattgt cctcatctgt gatcggaatg ctgcgacgag
     6181 aaatcatatc tcctgcatcc atttccttaa ccatttccat gatggtcaca ccagcttcct
     6241 catccccttg aatcaaggca taatggatag gcgcaccacc acggtgtcta ggaaggaggg
     6301 aggcatgaac gttgacagca aagtccatgc tatcaaggag tttgcttggg agaaactgcc
     6361 caaaagcagc agtcacaatt ccatctgctc ctagctttat aagttcttcc atctctggac
     6421 ttccagataa tttttcaggt tggtagatag atagtcctgc ttccttggca gcctgcttga
     6481 ctggggtttc ttggataact tttttacgac caacagcacg gtctggctgg gtcacaacgg
     6541 ctagaatttc gtaacggtca tctgtcaaaa gtccttttaa gactgttgct gaaaagtcgg
     6601 gggtccccat aaagattagt tttgtcatat cttctccttt ttataaaaat tgctgcggct
     6661 catggtcaat gctgagacgg agctcactat tttcccgttc ttgagtcaag gccaagacct
     6721 ggttgagggt cggccccagc tcatcttcta aacggtattt aattaaaatc tggtaatgat
     6781 agaggttgtg ggtacgggca atcggttttg gcgttggccc cagaatggga ctggtctctg
     6841 acaagcctga ccgcaaaatg ttcatgactt cataggcacg tttgaaaacc tcttcttctt
     6901 tcttgtgaga aagggtaata ccaatcgtga aatagtaagg tggatagccg agttgtcgtc
     6961 tgattcccat ttcataggca taaaagcctt cgtaatcttg atccttggca aatcgaatag
     7021 catagtgctg cggattgtag gactgtatca agacttgacc tgccttttca gcccgacctg
     7081 ctcgacctgc cacctgagtc aagagctgga aggttctctc agaagaacgg aaatcaggca
     7141 gattcaaggc cgtatccgca tttagaactc cgactagggt aacattggga aaatccaaac
     7201 cctttgcaat catctgagta ccaagtaaaa tatccgcttc ccctcgccca aactggtcaa
     7261 gcaaggcttg gtgactgcct ttctttcgag tcgtatccac atccatcctc agaatgcgag
     7321 cttggggaaa gagttctgct agctcatcat aagccttctg agttcccgtc ccatagtaac
     7381 gaatactgtg gctcttacag ttaggacaga cctgaggaat atccttcgag aaaccacaat
     7441 aatggcagtc catagtcttg gtatccatat gcaaggtcag agaaatatcg cagttgggac
     7501 aagtatccac cgtcccacac tcccgacaca tgacaaagct agaataacca cggcgattga
     7561 gcatgagaac cacctgctct tttttaacca gacggtcttg gatagcctct agcaaaggag
     7621 gcgtaaagtt tgacgtctca ttttgtccga tatagtctcg aaagtcaatc acttgaacct
     7681 cagggattgt agccaaagga ttggcacgtt gggttagacg taagtgttga tagacgcctt
     7741 tgccagcacg cgcccggctc tctaagctcg gcgttgcaga tccaagtacc agagttgctt
     7801 gattatactg agcccgtaaa atagctacct ctctggcatg gtaacgggga ttgctttcct
     7861 gcttataagc cgcttcatgc tcttcatcaa taatcatgac acccagattt ttcagaggag
     7921 caaagatagc agatctggca ccaacaacaa cttgggcatc gccacgctcc accttgcgcc
     7981 attcatcata cttttcacca ttggataatc ctgagtgaag aatggctacc ttgtccccaa
     8041 agcgtgctat aaaacgctcg gtcatttgag gagtcaagga aatctcaggt accagcaaaa
     8101 tagctgtctt gcccttatcc agggcacctt ggataatctg caagtaaacc tcggtcttcc
     8161 cacttcctgt aatcccttga agtagaaagg gaggttgaga actgccaata gaactcacaa
     8221 ccgcatcacg cgcctgtctt tgttctggat ttaactccaa aggtctactt gcttcaattc
     8281 cttcaaaata agcagccgag cgttgaactt ccttttggac tatggtaaca gcaccttgat
     8341 ccacaaagaa gttgatttgc tctcgcgagt aggactctaa caagctagcc aaggaagcgc
     8401 tctctggatg agacagcaga taatctctca gttccaactt tttcttggca cgtgtagaaa
     8461 tctcaacacc ttctaattga gcatggtcaa cctcatacca agactgggtc ttgaccttct
     8521 tttgatcgac tgcctgatat tccagaccaa gcaggccttt tctagtcaaa cgcatcattt
     8581 cagcttgctt ggcaaggtct agtgaagaaa aggctagcga atcttctgaa ccaaacaggc
     8641 gcactcgttc ttcctgactc aagccttcca gaggatagag aatcttgtca tagctagaat
     8701 tcagaaatcc tggaagcatg gccttgagga tagaaatttt gtaggagaag acagatttgc
     8761 gtaactcctc agccagccag agttgttctg gcgtgagaac aggagaaaaa tccagcacct
     8821 ctgcaatatc ttttaaatct tgctccatct cttctccatc tgattgggac tccaaaccaa
     8881 gaacaatccc ttgaatcagg cgattaccct taccaaaagg cacatgaacc cgcatcccaa
     8941 cttccagcat tccctcaaat tcctccggaa tcctgtaact atagggctgg tccgtctgca
     9001 tcaagggcac atctacgata atcttagcta gggccatcgt ctcacctcct ccttgtcagt
     9061 acattcttgc aatagaaaaa ataagattga gtccccccaa ccttaaattt tttcaccatc
     9121 ttctttttct ttagcaattt gctctttgat tttcttttct tcttcttctt tgcggcgttt
     9181 ttcttcttcg atacggcgac gcactgcttc acgttttcct tctggatctg ggtgaattgt
     9241 aacgtttcct gattcgattt cttctaaagc gcgaagagtt gatttttcag acttgaaacc
     9301 ttgagttgct ggggcacctg cttccaattc gtgggcacgt tttgcttcca agattacgag
     9361 tgaatatttt gaaggaacct tgtcgagcaa ggtatcaata gagggtttta acatcatttg
     9421 cttgtaccta ttttctaaat tttatcgggt agttggagat tttggtaaca tctcctgata
     9481 gtgaccaatg acacgatcca cacagaagtg ttctgcttca atcacacatt tgacacgttc
     9541 agcagctagg ggcacctgat cgttgacaat cgcataatca tactcacgca tgagggcaat
     9601 ttcttccttg gccttttcga ttcgttgggc aatcacttct gcactatctg ttccacgacc
     9661 taccaagcga tcttgcaatt catccaaatc tggtggtgtc aggaagataa agacagcatc
     9721 tggaaccttt ttcttgacct gaagagcacc ctgaacttca atttcaagga aaacatcgat
     9781 tcccttgtcc aaggtttcat tgacataggt cagaggagtt ccatagtagt taccgacata
     9841 ttctgcgtat tccaacatct gtccttgacg aatcagctct tcaaattctt cacgagtacg
     9901 gaagaaatag tcaacaccgt ccacttctcc aggacgttgt gcgcgtgtcg tcatcgatac
     9961 agagtattga aattggtttt cagaactctc aaaaatctct cttctaaccg ttccttttcc
    10021 aacccctgaa ggaccagaaa aaacgattag taagcctcgg tctgccattg tgtctccttt
    10081 tagtcaatct gtgaaataac atttctctag aataatggca aaaagccaga ttatccttta
    10141 cagtctttct atctagtgta acaaaaaagc agtaattttt caactgctct ttcttattta
    10201 tttagcataa tctactgcac gaagctcgcg aatcacggtt accttgatat ttcctggata
    10261 atcgagattg ttttcaattt tcttacgaac tttgtgagcc aagattgtga ctttgtcgtc
    10321 cttgattttt cctggattga ccatgatacg aatttcacgt cctgcttgaa gggcaaagct
    10381 agtttgcact ccttcaaagc cgttagcaat ttcttccaaa tcatggagac gcttgatgta
    10441 gctttcaaga gactcactac gagcacctgg acgggctgcg ctcaaggcat ctgctgcagc
    10501 gacgataact gctatcacgc tctcagcttc aacatctccg tggtgactag caatcgtatt
    10561 caccacaact gggggttcct tgtacttacg ggccaattcc ataccgattt caacgtggct
    10621 accttcaacc tcatggtcaa tggctttccc gatatcgtga aggaatccag cacgacgggc
    10681 aagagccgca ttttcaccaa gttcgctcgc catgatacca gccaacttag caacctcaat
    10741 cgaatggcgc aaaacatttt gtccatatga agtacggaac tgcaaacgtc ccataatctt
    10801 catcaagtct ggatgaaggt ttggcgcacc aatttcatag gcagcagcct caccgtattc
    10861 acgaatctta ttgtcaatct cttgacggtt tttctcaacc aactcttcga tacgagctgg
    10921 atgtatacga ccatctttga gcaacatttc catagtcata cgggcaatct cacgacgaat
    10981 cggatcaaat cctgacaagg tcaccacttc tggtgtatcg tcgataatca catcgacccc
    11041 tgtcaaactt tcaaaggtac gaatgttacg accttcacga ccaataatgc gtcccttcat
    11101 agtatcgtct ggcagatgaa ctgttgagtt tgttgactcc gctacatatt caccagcgat
    11161 acgttgcata gcttgaacca agatgtcctt ggccattttg tcagaacgtt ccttgatctc
    11221 ttgctcagct tcgcgaatgc gactggcaat ctccctggtc aagttttcct ctgtctgagc
    11281 caagataata tctcgtgctt ctgcctgaga cagagcacca atacgctcta gttctgcttc
    11341 tttttgtctt tcgacttcct ctaattgctc ttcacgcgca tcaaggtttt tcgctctatc
    11401 agaaatactt tgttcttttt gttcaagtgt ttgttcttta ctcgtcaaat tgtcgtcctt
    11461 acggtcaagg ctagtagctc tctctgtcaa acgactttcg atttgtttga gttcttgacg
    11521 ttctgattta aattcagcgt ccacttcttc acggtatttt ctggcttctt ctttggcctc
    11581 caatagtgct tcttttttaa gagacttact ttcacgtttg gcttcattaa caagtaaatc
    11641 cgcttcacgc tcagcttgtc cacgtaaatt agttgcttct tgttcagcat ttaaaagcat
    11701 caactctgca gcttcctgag atgatttcat cttagctgag atgctgacat atccaatgac
    11761 taaaccaatg atgacggcaa aaacagcaat cgcaagcgac atgatttcca tgtttttacc
    11821 tcattttatt gttattccga atgacataca ttcttttaca ttctaccata aaaaagggat
    11881 tttcacaaac ctaaaataga atatgttttg gggaatttgg aacacattta ccaaaataaa
    11941 cttgttgttt agaaatagta gtttagtaga gacttgagaa aaagcctact ttgcagtaga
    12001 cttagtaatg atctttaaag gacaagaaag ccacgctatc tccatccatc atataaatca
    12061 agcgattttc tgcatcaata cgccgtgacc aggctccttg gtaatcatat ttgagtggct
    12121 ctggttttcc tattcctgta aatggatcgc gttgaatatc cttgattaat ttattgattc
    12181 tttttagtgt ttttttatct tggttttgcc agtagcaata atctgcccag gcatcttctg
    12241 taaacttgag tagcattcat cactcctcaa tcacatggac ctgagtgctt ccagcacgga
    12301 cttgagccat tcctcgcaaa accttgtctg ataactcctt attttgggcg attctcaggg
    12361 tttcctgaat actgtcccat tcgctctttg aaagaactac aatgtcctca tctggatttt
    12421 tattgaccac cgtcaaaggc tcaaattcat catttacctt cttcatgtag tcctttaaat
    12481 gatttcggaa tgttgagtaa aggactgctt ccataaccat acctcgtttt agctcttttc
    12541 cactattata cacgaaaaga aagaaattgt caggaacttg tacaagattt tcttttctat
    12601 ctatttatac tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag gctgtacttg
    12661 agtacggcaa ggcgacgttg acgcgatttg aatttgattt tcgaagagta ttattcgtaa
    12721 aaaatctcaa aaagcctacc tttcggtaga cttagtttgt ttctattcta atcggcactc
    12781 ttccaaaatt ttgctctgct atacttggct ttcctagttg gtaaatctgg tctgcttttt
    12841 gggtcatagc atcccaaggt tctttgccaa ttcggctgac tagactgacc tgacctttca
    12901 aagatttgag atgttgcctg cctttttcag taaatccaag gacatgaatc gcttctggca
    12961 agttactttc tctaacctgc accaaaatat aggtcaatag gcgtctgaca cgcgccttgg
    13021 tgtaacgttt ggtagtcact aactcgacca attcttccac agactgggct gttttaatag
    13081 cttctttaat gcgcacagcc atttcttgat tgacctgata gatggtggtt aggtcgggat
    13141 ttgacaagat ttgatagcgg agcaagggaa aatagtcttc ccagctcacc ttactggcct
    13201 gctcaaagag ggcaacagaa ggcataaatc gttctaagaa atctttgtcc ctctggtgct
    13261 gacgaagggc tgtcgccgaa gcaaagttca catccttgtc cacagaatgg tagcctgccc
    13321 cctgacgctg aatcggatga agtttgatgt tgtacccagc aaccgccttg gcgtaagcga
    13381 gggcaagaac atgattgggc gtattgcctg aaaaatcaag acctgcaaat tccttccaca
    13441 tggcttgggt cttctgggga taagaaagag agtcaggcaa attttccaca aaattctcca
    13501 tctcagcccc ctgctctgtg tataagtcag cgattttttg ataatctaga acttcttctg
    13561 tcccaaaagc gaggctatct atgcccaacc gagctaagat atccacggcc ccttgaccga
    13621 aaaaatctgc cgcctgaacg ctgactaaaa agggcaattc cactaccaga tccgctccat
    13681 tttccagcgc catctgggct cgtgtccact tatccacgat agcaggttct ccacgctgca
    13741 tgaaattccc tgacatagcc acgattttca gcccctccgc ttgatccagc aggtatttgt
    13801 gtccattatg aaaaggattg aactccgcga taatacccgt gatggtcata gtaatctcct
    13861 acttctgcgc cacaaaaaac caacgggtgc tagtttctgt tggctcctta tcctcaaagt
    13921 ctgcatagag tttgaaggac ttgaatccag cctgttccag caagatatca taggtcaaga
    13981 tctcataggt cctctcctca tgtacttcat cgtggcgact aaaggaaccg tcagcctcct
    14041 tgataaagaa agtcagctca tgcacgatgg agtgaggagc ttcgtcctca tatgtatccc
    14101 aaagcatgga aaaatcttcc gcattttcat ggtaggaata gccagggaat acttcatctg
    14161 tctggtaggt cgagtgcacg tcaaagatga aaactccctc ttcattcagc gcattgtaca
    14221 cgtccttaaa gacgtcccct acttccacct catcctgcat atagcagata gagtccgaat
    14281 aacacgtgac aaaatcgtat ttccctgcct tggacaaatt cagcatatta ccttctataa
    14341 aagcaatctt ttgcttggct gaagttgctc tcttctccgc aatcttcaac atatccgcac
    14401 tcaagtcaag tccagtcaca tcaaaaccag cctgagagaa gcgcactgat tgaattcctg
    14461 tcccacaagc cagttccaag agtttctttc tctccttggt cttaggcaaa tgacgcagag
    14521 aaaaattcgt ccatttgtcg tataaactat cgtccatgac cgcatcatag accgccgcaa
    14581 aggtttcata agtcgccata atcatgatac taagagctcc atggtaaaca ccactagccc
    14641 tttacctttc tatcaatttt tctaaaataa gcaaagaaac ccagttgact acaactgagt
    14701 tcatcttcta agcaagagct tctgaaatat ctactgaatt cgcctcatgc catagcttct
    14761 ctagattata atgggcacgc atttcttctg aaaagatatg cacgacaaca gcaccgaggt
    14821 ccagtaagac ccagcctcca gctgcatcgc cttcgacatg gctaccttta aagcccgctt
    14881 gagctacttt ttcacggata ttagctgcga tagcgtccaa ctgacggcta ttcattgagc
    14941 tagtgatgac aaagtagtcc gtcacactag tcaaatcttg tacatcaagt gcgaggatat
    15001 cctccgcacg tttctcatca gccgctttca cgactagttc tagtaattct ttttcgttca
    15061 tttaatcctc tttttagaaa atatgtttgt aatctaggac atctgcaaag cgctcctccc
    15121 aaatgtcctc ataaaattca ttaatcgttt ctgctggaat gtcatcccca tcaaaggttg
    15181 tgacagcacc ttctggaaca ataagctgat agccatattc aaaggcaacc ttgacagaag
    15241 tatccacaca atattctgtc tgcataccac ataaaactaa tttttcaatc ccctgtttat
    15301 ccaagtattc ttttaagcca gtttctttga aaatactgtt atacttcttc tgaaagacct
    15361 tttcagcagg ttttcgattt aaaagcgcag ataactgcca atcttctgat gtttgagctt
    15421 cagagttctc aatatgttga acatagataa tttcaatatt cttgcttcta gcctggtttt
    15481 gtaaataaga aattttttcc aatagacttt ttgtctggaa cccagtttct actaaaatat
    15541 tctgaacatc aatgattata aaagccatct tcatttagtt ctctttcaaa tagtgcacaa
    15601 aggcgttata ggtttcaagg gtttggggat agatggggaa tccctgatga gctagatact
    15661 ccacggtacg agctgtttcg taggccaccg ccttattgag cgatagactt gcaatctcac
    15721 gcgccacatc tactccagga aaggctcgat tgtgctcgat atagtctgcg acgtagatga
    15781 ccttatctag gtctgtcatc tgaccagcac cgactgtatg gacttcaatg gctcgcagga
    15841 tttctgaatc atgcaaatcc aaatcttcct gaattttgta aattccgacc ataccatgcc
    15901 agacattatt accccagttt ttgaggtcga aatctagctg ataacggtca atcaagtcta
    15961 gaaattcctg atctgacaac tttttagcat agtcatgaag aagacctgct agacttgctt
    16021 tctcaacatc tacaccaaag cgctgagcta attccatagc ggcacgctcc acacctagac
    16081 aatgggttag acgtttctca ggtagaagct ctgccatttt ttccaacaag gcctcacggg
    16141 agcagttgat atagtcttga taggacatca gtagagcccc tccttctcga tgtagtctag
    16201 cactggctga ggtaggagaa agttgggttt ccgaccttgg gcaaggaagt cccgcaccat
    16261 gctggacgag atatccatga gcggtacgtc cacccagata actggatagg aagtccctgc
    16321 cttgtagcgt ggacgctgaa cccccacaaa ctgaaccatg tcaaccagtt catcaattcg
    16381 gtaccactta ggcagatagt caaccatgtc ggcgccgatg ataaagtaat aatccgtatc
    16441 tggatgttgc tctgtcaaga ttttcatggt gtcgtaggtg taggaaatac ccttgcgctc
    16501 caactcaata gtttcaatga ctaggccgtc aatcccctca attgccaact caagcatctt
    16561 gagacgatgg tgttcaggga tggtttcctt tttatcaacg tgaggaggtt ggtattcagg
    16621 catgagcaga acttgatcca gtcccaactg ttgccgtact tgatccgcaa caatgagatg
    16681 ggcattgtga acagggttaa aattcccccc taaaatccca acttgtttgc gttttttctc
    16741 cttgatttct ggctccaact ctaccttggt aaagggagtc aatagttcga ttgtcatagg
    16801 ctagtcccct ttatttctct ataaaaacag ttatttggag tttcggtctt agatttcttt
    16861 gactttctta gaaatcttgc gattttcttt cttgctagat tgtttaaaca aaatcaagat
    16921 gcgtcctatt ttttggactg tatccacacc gatttcttct tccaaaattt cagctacttc
    16981 gtggatgttt tcatctgtgt tttgtaagag agtaaccttg attaattcac gcgcatcaag
    17041 agcttgacgg acgctggttt tgatttggtc gttgagtcca tttttcccga tttggatgat
    17101 aggtttgagg gtgtgtgcct ggctgttgag gaaggcacgt tgttttgatg ttaatgacat
    17161 aattttcttc cttgtttttt gatagttatt ttaggtggtg agggacggtc ggaactaatt
    17221 ttccaaagat ttcatctttg aaaaatggat ttcctgacct cacaattgag ccttggtctc
    17281 aattgtgccc cttgccaatc tacagattgg caatcacacc acggcaataa ctatcgctat
    17341 atgagctcac tttgttcgct cagcgatttt gttttaaata attgcttttc gtgtgacgac
    17401 ggcgacgcct tctggtgccc agacggcgac ttttgctatg cctgttacac gaatccagcc
    17461 taggcctgag atgactaggt ctgtcttatc tttaatggta aagacatgct ggactagcct
    17521 tgggaaatct tctttttcct tgctatttgg tggtgtcaga agagttccca ggtgcttatc
    17581 gtagaaagca ctagctcctt caagcttgct acgatggagt ttgagttcat tatcaaagaa
    17641 agcagtaaat ccttgctttt ctcctgctat aaagtcaaag cgtcccaaac cacctaaaaa
    17701 tagggtttgc tcaggattaa gctgataggt cttaggcttg atttcctttt taggactgac
    17761 atacttgagg tttttggccg tcaagtagtg agccatctgg tggcggtgga taattcccgg
    17821 cgtatcgtaa atataagatc cgtcgtcaag cggaatctct attttgtcca aggttgtacc
    17881 tgggaagcgt gaagtagtga tgacattctg atcacccgtg atttcttgga taatagcatt
    17941 gattagagtt gattttccaa cgttggtcac accgaccaca tagacatcgc ggcccttacg
    18001 gtagtgttca atcttgtcaa tgacttcctt aatggcatgt ttattttgtg ctgaagttag
    18061 gaccacatcg actggacgaa gaccttcttc atgggcacgt ttcatgagcc actggctaat
    18121 cttaccagac ttaactgact taggaaggat atctttttta tttcctacca agaggacatc
    18181 attgcccgag acgaaacgtg gtaaacctgg gatgacagat ccattaaaat caaagatatc
    18241 aatgacattg accactaagg catcactgtc tcccacctcg tgcaagagct tgaggaaatc
    18301 atcgttcgtc aactggacat ctgtgatttc attgtagtgg cggagacgga aacagcgttg
    18361 gcaatagact tcgccagtct ccaaaccttt ttcaagtgcc gactgggggg taaaaccaag
    18421 accagcttta tctgtcgtct gaatggttgc tccacaacca atacagagaa tttcttccat
    18481 agttaaattc cttttttata tgtaatcggt ccgtactttt cagtgatttt tctcataaca
    18541 cgacgctcac gagttcggtt aatctgcgtt ttgattgagt catgttggac caagggtttg
    18601 actaaaattg accgaatccc tgcacggtgg gctgctcgta tatctgtcat gagctggtcg
    18661 ccaaccatga ccacttcctt tttgtcatag tggaattcct tcatagcacg gtcaatacca
    18721 aatgtgaagg gcttcaaggc ccagtaaacg taatcaatcc caaatttctc aactgctcgt
    18781 tgaacgcgtt ttttggtgtt atttgacact acgataatgc caatacccgc gtcccgaagg
    18841 tcatgtagcc attgcttcat ctctggcgtt ccatcagggt tgttccaagc aatgagggta
    18901 ttatccaaat cgaccaaaac agccttgatt ccctgcgcct gcaggcttgg gactgtcaga
    18961 tcatagactg cttccacagc aaaatctggt atataatttt caatcgccat tctggctcct
    19021 tttcttaact ttttttcgca attttcctta gtaacaagga taaaacaatc cacaaacctg
    19081 cactagccaa actgatatag agccaagcat ggggctcatc tgttaaaggt aagggaacat
    19141 tcattccgaa aaagcctgtc acgactgcca aaacagctag caagactgaa atgatagtca
    19201 aggttgtcaa attgtcattc agattattgt ttagaatatt gttgtaagag gctgaaagct
    19261 gctgtaaaat ctgagagatt aggtctgtca tggataccag ctgatgagcc tcaatcatgg
    19321 catcatcaaa ctgttctctc tcaatctcat caaaactacg atacaaggca tgaccttgaa
    19381 tatgctctaa caaaatccga ttttgtttgg cagctgccgt cagataaacc ataccagtct
    19441 ccaaatcaga cagggcaaag aggtttttct tggtagttcg ctggcgcaag aggtcattga
    19501 cctcatccct actcttgtcc atctgctcaa tgacaggata gtaggcattg ctgataattt
    19561 ccagactggc aaagagaaac ttataaatcg aaagcgtgtc atggctctcc agataacgag
    19621 tcatctgttc aatgacatag gcgttcttgg tattactaat ggtaatcagg cgacgatgct
    19681 cgacaataaa ggtcatggga aaagtctcat agtaggcctt gtcctttttt acgtctagga
    19741 cattatagat aaaggtaacc gtcccacttt cacggtggta atccatgtgg gcgcgctcgt
    19801 ttctatccag tgcgtattca atggtttcct tgtccaaacc gtaaatttca gaaaggtctt
    19861 ctagtttatt caactttcct aggtctaggt ctatccaggt acaaccattg cccaactgct
    19921 tttctaaaac catcttttct ccttattaaa ctccctctat tgtaccacaa attacttaaa
    19981 ataacaggtc tagtctgtgc gtgagaaatt gctaacaact gtgatatttc ggttagggac
    20041 aaagtgaagg gcttgctcct cgctacgaag ctgtgtcgta cgaattccca cactgacaac
    20101 cttacccgat acagtaatcg gtccatttgt cagaacgacc tcatctccca catccagttg
    20161 acgttcaaag aggatgaaaa agccattgat gacatcagac agaaagcctt gggctcccat
    20221 accaatcgct accccagcaa taccagctcc agccagcaaa ctagaaactg gcaaacctaa
    20281 aatcgacaaa atgcagtaga gtaaaaagaa atatagcgta taattaaaca cattttctag
    20341 taaacgtgag atggtttttt ggcgtccgac atcatgacga gacattttta gagaaggttt
    20401 gacaattctc tgcaccatgg tatgaagcat ttttttagca atataaaata caatcaaaag
    20461 cagtaaaaga gaaatgacct tggttagaat attctcgata atggttgtca catctagctt
    20521 ttcaatataa gcctgaataa atttttgcat ataaaactcc tttatttcat tataccatat
    20581 tttcatcagt ctcattctcc ataaatattc aaaaatagac agaaaattct tgattttgtc
    20641 tatcatttat actataatca taatcactac acaaaaagga gattattatg aaaagaatca
    20701 ttcatgcttg gaataaggca agccttgtca agcgtatctt gattggtatg ctttgtgggg
    20761 attcctagga ctgacccttc ctaatctctc agggattggg ctactcgggg atttattcgt
    20821 tggagctcta aaagctgttg ctcctatcct agtctttgcc ctcgttgcca atgccctttc
    20881 ccaacatcaa aagggacaag atagcaatat gaaaactgtt gttttcttgt atatcctatg
    20941 atagggactt tcgccgctgc tcttgtagct gtactagcaa gtttcatcgt ccctattgaa
    21001 attaccctaa atagtgccaa tactgaaatt gcaccaccag atgggattgg gcaggtcctc
    21061 agcaacctct tgctcaaact ggttgacagc ccagtcaacg ccctgcttac tgctaactat
    21121 attggaatct tatcttgggc agtcattttt ggaatcgcta tgagagaagc cagtaaaaat
    21181 agtaaagaat tgctaaaaac tatcgctgac gtgacttcta aaattgtcga atggatcatc
    21241 aatctggctc catttggaat ccttggtctt gtttttaaaa ccatttctga caagggagtc
    21301 ggaagccttg ccaactacgg tattttattg gttccattag taacgactat gctttttgtt
    21361 gcccctgtgg tcaacccttt gattgccttc ttctttatga gacgcaatcc ttactctcta
    21421 gtttggaact gcctccgtgt cagcggtgtg acagcctttt tcactcgtag ttctgcgact
    21481 aacattcctg tcaacatgaa actctgccat gaccttggac tcaacccaga tacctattct
    21541 gtttctatcc cactcggttc tactatcaat atggctggag tagcgattac cattaacctt
    21601 ttgacccttg ctgcagttaa cactcttgga attcctgttg actttgccac agcttttgtc
    21661 ctcagtgtgg tagcagctat ctcagcctgt ggtgcttcag gtattgccgg aggttccctc
    21721 cttcttatcc cagttgcttg tagccttttc ggtatttcta acgatattgc catacaagtt
    21781 gttggggttg gttttgtgat tggtgtcatc caagactcat gtgaaacagc ccttaactct
    21841 tctacagatg gcctctttac cgccgttgcc gaatacgcag caacccgtaa aaaataactc
    21901 atcaaggcaa gcctgctcat gtcttgtctt ttacgctttt attctaactt attaggaaat
    21961 tcttatgtct attagccaac gtacgaccaa gctcatctta gctacctgtc ttgcctgcct
    22021 gcttgcttat tttctcaatc tttcgtcagc agtttcggct ggaattatcg ctctcttgag
    22081 cctatctgat acgcgtagaa gtactttaaa actggctcgc aatcgtcttt tttctatgct
    22141 tctagctctg gctattggtg ttctagcttt tcacttgagc ggatttcata tctggagtct
    22201 cggcctctat ctggccttct acgttccttt agcctacaag atgggctggg aaattggcat
    22261 cacaccaagc actgttttgg ttagccatct cttggttcaa gagtcaacct ctccagacct
    22321 tctagtcaat gaattccttc tctttgctat tggtacagga tttgccttgc ttgttaatct
    22381 ctatatgcct tcacgagaag aggaaatcca gcactaccac acgctggtgg aagaaaagtt
    22441 aaaagatatc ctccagcgct tcaaatacta tttatccaga ggagacggac gcaaccgagc
    22501 acagctggta gcagaattag acacgctttt gaaagaagcc ctcagactgg tctatttgga
    22561 tcactctgac cacctctttc accagaccga ctaccatatc cactactttg agatgagaca
    22621 acgacaaagt cgtatcctga gaaacatggc ccaacagatt aacacttgtc accttgccgc
    22681 cagtgaaagc ctgatcttag cgcaactctt ttcaaaaatt gcaggtcaac tgagccagac
    22741 caatcctgct tctgatttgc tagatgaaat tgaacgttat ctggaagtct tccggaaccg
    22801 cagtctgccc aagacaagag aagaatttga aacccgcgcc acccttcttc aactcctacg
    22861 tgaagccaaa accttcatcc aagtaaaagt tgacttttat caaaaatata gacagtaaaa
    22921 aagaaaacca ctaaaaaaca gagcttgcca gcattcttga aaagtagtat aattattgca
    22981 tgcgcaatca tcttgtgacg cagagactgc ccgttaatgg actttcttct atttatgact
    23041 ctaaaaagaa aggagacact atgacctatt tggaaaaatg gtttgacttc aatcggcgtc
    23101 agaaagaaat tgaaagtctc ttggaagaga ccattgccca acagagcgag caaagtctga
    23161 ccttgaaaga gttctacctg ctctactatc tggacttggc tgaagaaaaa tctctacgcc
    23221 agattgatct gccagataag cttcatctga gtccaagcgc agtttctagg atggtggctc
    23281 gcttggaagc taaaaattgc ggtctactca gtcgcatgtg ttgccatcaa gatagacgct
    23341 ctagttttat ctgcctgacg aatgatgggc aaaagacact ggcctcgcta caaaagactg
    23401 tcgaagaaag cttggaagca ggtttggatt tcttgattta agatgatttt agaaaaagtt
    23461 gcgtgcgcaa tcatttttct tgacattctc ttttataagg agtaaaataa agttagcatt
    23521 aaacaaagga gttttaaata tgattgaaat tacctatata gatgccagca agaacgaaag
    23581 aactgtgact ttcgagtctt atgaagactt tgaacgttcg caacaagctt gccttatcgg
    23641 cgtcgcagac tactaccctg tccaaaaatt aacttacaag ggtcataatt tggactacca
    23701 tgggacttat ggagatatct tcttctatct catgaaacaa gatttaagcc aatataacta
    23761 aaaaaaggag aaatacaatg gcaaaagcaa ttacagatgc aacattcgaa caagaaacaa
    23821 aagacggttt ggtcttagta gacttctggg caacttggtg tggtccatgt cgtatgcaag
    23881 gtccaatctt ggacaaattg tctgaagaac tttcagaaga tgtcttgaaa atcgttaaaa
    23941 tggacgttga tgaaaatcca aacacagctc gtgcttttgg aatcatgtct attccaactc
    24001 ttctcttcaa aaaagacggc caagttgtca aacaagttgc aggtgttcac acagcagaac
    24061 aaatcaaggc catcattgct gaattgagct aatcaaacga gagaccaagt actttctttg
    24121 gtctcttttt tcttgccctt tgccattttt caaaaaatat gctagactat agtagattga
    24181 aactagaata gtacacctct acttctaaaa cattgttaga aatcgatttg actgtcctga
    24241 tcgatttgtc ctgttcttat ttcattttac tatataagta gaatattacg atgtttggga
    24301 tatgccatcg ctaaaaaaac ctcgatttgg tattttttag ctccctaatg ggagcttttt
    24361 gcgtgctctg aacatttccc attttggaag gagtactatg aaacgtcaat cagccttggt
    24421 cgtctttagt ggtggtcaag attcaacaac ctgccttttc tgggccatgc aacactatga
    24481 aacagtcgaa gctgtcacct ttgcctacgg ccaacgtcat cacctcgaaa ttcaaattac
    24541 tagagaaatc gctaaggaac agggcattcg tcaccatatc ctcgatatgt ctctgctggg
    24601 acaaatcact gctcagccag actttgcgac gattcatatt tcctacattc ctgacaagct
    24661 ctgtgtcgag tcaaaatccc tcaaactata tctatttagc taccgaaacc acggagattt
    24721 ccacgaaaac tgtatcaaca ccatcgggaa agacttggtc aacttgctag accctcgcta
    24781 tttagaagtc tggggaaaat tcactccgcg cggtggcatt tcaatcgacc cctactacaa
    24841 ctacggtaag caaggaacta agtatgaggg cttggcagaa caacgcctct tccaacacga
    24901 cctttatcca gagaaaattg acaagcgcta aactcatact caatgaaaat caaagagcaa
    24961 actaggaagt tagccgcagg ttgctcaaag cagtgttttg aagttgtaga tgaaactgac
    25021 gaagtcagct
//
LOCUS       DBERPV010000029        24995 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.29, whole genome shotgun sequence.
ACCESSION   DBERPV010000029 DBERPV010000000
VERSION     DBERPV010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 24995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24995
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.29"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            432..1142
                     /gene="deoD"
                     /locus_tag="ACL8C7_001497"
     CDS             432..1142
                     /gene="deoD"
                     /locus_tag="ACL8C7_001497"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGS1395672.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(1165..1689)
                     /locus_tag="ACL8C7_001498"
     CDS             complement(1165..1689)
                     /locus_tag="ACL8C7_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HGS1395673.1"
                     /translation="MKIAIIGYSGSGKSTLAEKLSNYYSISKLHMDTLQFQPGWQDSD
                     HEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFDWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(1742..1978)
                     /gene="rpsT"
                     /locus_tag="ACL8C7_001499"
     CDS             complement(1742..1978)
                     /gene="rpsT"
                     /locus_tag="ACL8C7_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HGS1395674.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(2046..2966)
                     /gene="coaA"
                     /locus_tag="ACL8C7_001500"
     CDS             complement(2046..2966)
                     /gene="coaA"
                     /locus_tag="ACL8C7_001500"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HGS1395675.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            3156..3560
                     /locus_tag="ACL8C7_001501"
     CDS             3156..3560
                     /locus_tag="ACL8C7_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395676.1"
                     /translation="MKILKRYILELCFILSFALPFIKGANADNGRCFVETYYGFTFLM
                     EHAIVTAVFICSFLIAFLLKKRWTKWIAAGSYCFLVLRIATEGYFFHMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            3767..4357
                     /locus_tag="ACL8C7_001502"
     CDS             3767..4357
                     /locus_tag="ACL8C7_001502"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGS1395677.1"
                     /translation="MSKMYYAEHPDAAHDIHELRVDLLGEKMTFLTDAGVFSKKMVDF
                     GSQLLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLAQRNAEK
                     NNAKATIFQSNIYARVQGRFDHVISNPPIRAGKQVVHEIIEKSKDFLEIGGDLTIVIQ
                     KKQGAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            4354..5631
                     /locus_tag="ACL8C7_001503"
     CDS             4354..5631
                     /locus_tag="ACL8C7_001503"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HGS1395678.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDVLDYETGIVFEKKIGDSVQKGEIVSKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            5649..6311
                     /gene="deoC"
                     /locus_tag="ACL8C7_001504"
     CDS             5649..6311
                     /gene="deoC"
                     /locus_tag="ACL8C7_001504"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HGS1395679.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVRLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            6298..6687
                     /locus_tag="ACL8C7_001505"
     CDS             6298..6687
                     /locus_tag="ACL8C7_001505"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGS1395680.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAVFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            6777..7829
                     /locus_tag="ACL8C7_001506"
     CDS             6777..7829
                     /locus_tag="ACL8C7_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HGS1395681.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            7973..9508
                     /locus_tag="ACL8C7_001507"
     CDS             7973..9508
                     /locus_tag="ACL8C7_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1395682.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQGLGVLMAGGNLGKEK
                     SDV"
     gene            9501..10559
                     /locus_tag="ACL8C7_001508"
     CDS             9501..10559
                     /locus_tag="ACL8C7_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1395683.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGSVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            10562..11518
                     /locus_tag="ACL8C7_001509"
     CDS             10562..11518
                     /locus_tag="ACL8C7_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1395684.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            11603..12952
                     /locus_tag="ACL8C7_001510"
                     /pseudo
     CDS             11603..12952
                     /locus_tag="ACL8C7_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(12995..13636)
                     /gene="plsY"
                     /locus_tag="ACL8C7_001511"
     CDS             complement(12995..13636)
                     /gene="plsY"
                     /locus_tag="ACL8C7_001511"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HGS1395685.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            13772..15715
                     /gene="parE"
                     /locus_tag="ACL8C7_001512"
     CDS             13772..15715
                     /gene="parE"
                     /locus_tag="ACL8C7_001512"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HGS1395686.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            15730..15934
                     /locus_tag="ACL8C7_001513"
                     /pseudo
     CDS             15730..15934
                     /locus_tag="ACL8C7_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014166.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
     gene            16135..18606
                     /gene="parC"
                     /locus_tag="ACL8C7_001514"
     CDS             16135..18606
                     /gene="parC"
                     /locus_tag="ACL8C7_001514"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HGS1395687.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLV
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEAILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            18738..19760
                     /locus_tag="ACL8C7_001515"
     CDS             18738..19760
                     /locus_tag="ACL8C7_001515"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HGS1395688.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            19816..20520
                     /locus_tag="ACL8C7_001516"
     CDS             19816..20520
                     /locus_tag="ACL8C7_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS1395689.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     STTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            20585..21274
                     /locus_tag="ACL8C7_001517"
     CDS             20585..21274
                     /locus_tag="ACL8C7_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0858 family membrane protein"
                     /protein_id="HGS1395690.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            21271..22194
                     /locus_tag="ACL8C7_001518"
     CDS             21271..22194
                     /locus_tag="ACL8C7_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0859 family membrane protein"
                     /protein_id="HGS1395691.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSVFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            22209..22853
                     /gene="pcp"
                     /locus_tag="ACL8C7_001519"
     CDS             22209..22853
                     /gene="pcp"
                     /locus_tag="ACL8C7_001519"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HGS1395692.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            23021..23251
                     /locus_tag="ACL8C7_001520"
     CDS             23021..23251
                     /locus_tag="ACL8C7_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HGS1395693.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            23301..23381
                     /locus_tag="ACL8C7_001521"
     tRNA            23301..23381
                     /locus_tag="ACL8C7_001521"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:23335..23337,aa:Tyr,seq:gta)
     gene            23391..23462
                     /locus_tag="ACL8C7_001522"
     tRNA            23391..23462
                     /locus_tag="ACL8C7_001522"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:23423..23425,aa:Gln,seq:ttg)
     gene            23624..24826
                     /gene="rpsA"
                     /locus_tag="ACL8C7_001523"
     CDS             23624..24826
                     /gene="rpsA"
                     /locus_tag="ACL8C7_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HGS1395694.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
BASE COUNT         7532 a         4411 c         5651 g         7401 t
ORIGIN      
        1 ggtttgaaga gattttagaa gagtataaac agaaaggtag agcgcgtgtt ctaatttgaa
       61 cacgagtaga aaacttttct aaaaacaaaa acgaaaggat gggtaaactg tattcgctga
      121 actgaatacg ggcgactctc ctctaaatca aaattaagaa aggaattgac cccaccctaa
      181 aagtagtggg aaaaagatag ttggtctagc gagcatcgct cactgcgccc aactcctatt
      241 ttcccttcgc tttttgatgg gtttggtatc tttctcaata taaaatataa aataaagaaa
      301 ggtagagcgc gtgttctaat ttgaacacga gcggaaaact cggaaaatag ataatctgac
      361 tgaaaaatca ggatttctcg tcaggttcct aattttcagt cgttttcttc tcgctctttg
      421 tatcataaat tatgtctatc catattgctg ctcagcaggg tgaaattgct gataaaattc
      481 ttcttcctgg ggatcctctt cgtgctaagt ttattgcgga gaatttcctt ggtgatgctg
      541 tttgttttaa cgaagtgcgt aacatgtttg gttacactgg tacttacaag ggtcaccgtg
      601 tatctgtcat gggaactggg atgggaatgc catctatttc gatttatgcg cgtgagttaa
      661 tcgtagacta cggtgtgaag aaattgattc gtgtgggaac tgcaggttct ttgaatgaag
      721 aggttcatgt tcgtgaatta gttttggcgc aggcggctgc aaccaactca aacatcgttc
      781 gtaatgactg gccacagtac gattttccac aaattgctag ctttgatttg cttgataaag
      841 cctaccatat cgccaaagaa cttggtatga ctactcacgt tgggaacgtt ttgtcatctg
      901 atgtctttta ctcaaattac tttgaaaaga atatcgagct tggtaaatgg ggagtcaagg
      961 ctgtggaaat ggaagcagca gctctttact atcttgctgc ccaataccat gttgatgcgc
     1021 tagctatcat gaccatctct gatagcttgg tcaatccaga cgaagacaca actgcagaag
     1081 aacgtcaaaa taccttcact gatatgatga aggttggttt ggaaaccttg attgcagaat
     1141 aattatagcc aaaaaggaag ccctttatga attgtaggac ttccttttct tatccagaaa
     1201 ttgatctagc tctctctgat ttcgaagaat agtgacttta tgtgaatatt cttggcaaag
     1261 tttttggtaa ttttcttttt gagttttgct acgtccatcc caaagaatcc atctgataaa
     1321 ctcccagtca aagcgttcag ggcaatctgc cgccatactt tctctgactt ttccacggta
     1381 tttaagataa cgcttaaagg ctctaaagag acaggtcaat ggcgaaaaat tgagaaagat
     1441 gatttggtca gcttcttgca ttcgttcttg gtagtagcac caagaataat taccatcgat
     1501 gacccaagct ttatgcttgg tgagaaagtt ttttatctcg gttaacatcc attcgtggtc
     1561 actgtcttgc caaccaggtt gaaattggag tgtgtccatg tgcagttttg aaatggagta
     1621 gtagttagat aacttttctg ctagagttga cttaccagaa ccagaatatc cgataattgc
     1681 gattttcatt ttctaccttt tcctatttgg agacaaaaaa acagcctcta tggactgttt
     1741 cttatttagc aagtttagct gaaagacgag ctttatcgcg gcttgctttg tttttgtgaa
     1801 tcaaaccttt agtttctgct ttatcgatag ctgagctagc agcacggaaa agttcttcag
     1861 atgggtttgc ttcgaaagct tttatagcag tacgcatagc tgatttttga gctgagttct
     1921 tttcgttttg tttaacgttc aattcagcgc gtttgatagc tgatttaatg tttgccaatg
     1981 ttcttacctc catatttact aactatacca ttatatatga aaacttacgt tttgacaagg
     2041 gaaaattatt tttttaagta aatttcatcg atttcatggt tcttgctttt atgaagaatc
     2101 acttctgcac gatttctggt tggttcaata taattttgta gatttgtgag attgatactg
     2161 gtccagacct gatgggcaaa ggcttccact tccccaatcg gcatctgagt aaaacgataa
     2221 tagtagctat cagggtcgtt ttgggctaga ctcagcattt tcaagaaacg gtccagatac
     2281 caactttcaa tatcatccac tccagcatct acatagatgg aaaagtcaaa gaagtcagtg
     2341 atatagagac gatcgttttg tggattttga aagacattga ttccctcaac aattacaaaa
     2401 tcagcagctt tgacactttg tttctcttcg ggtacgatgt cgtaaacttc atgagaatag
     2461 acaggaatat ctacatcttg tccatttttg atgcggtcca agaagttgag aagagcttcc
     2521 atatcatagc tttcaggaaa tcctttacga tttaaaatcc cctgctcaat caaggtttga
     2581 ttgggataga gaaaaccatc agttgtaacc aactcaaccg tagcatctgt aaacgtacgg
     2641 gacagtagga tttgaagtag gcgactggtt gtggattttc caacggcaac actcccagaa
     2701 accccaataa taaaaggttg agatttactt tcacgttgga ggaaaattcc ttttgaaaag
     2761 gctaaatctt ccttagttcg cttgtaaatc tgaatcagat gagccaaggg gagatagata
     2821 tctgtaacgt cttggagact gatttggtca ttaaaactct tgatagattc caattcttct
     2881 tctgtcaaag gaggtgttgt ctttcgatgt aaagattgcc aagtctggcg gctgattttt
     2941 tcaaaatgta aaaattcgtt ggtcatttgt tttcccctag atattttgtc tatcatacca
     3001 taaaaagcta aaaaaataaa gcggtttctt gaatgtggta agtcaatggt atatagtata
     3061 agtgatcaat ttattgatga aataggagat agattctact gatttataag cttataaagg
     3121 gggctttttg gttcacaact tataggaggt gtactatgaa aatcttaaaa cgttacatat
     3181 tggaactctg ttttatttta agttttgctt taccttttat aaaaggagcc aatgcagata
     3241 atggtagatg ctttgtggaa acctattacg gttttacttt tttgatggaa catgctattg
     3301 taacagctgt ctttatctgt tcgtttttaa ttgctttctt actaaaaaaa cgatggacga
     3361 aatggattgc tgcgggtagt tattgctttt tagtcctacg gattgcgaca gagggttatt
     3421 tcttccacat gtcactagaa gatttgatac gactttggac aagtttggaa atcctgacac
     3481 aaacgtatca gttgggcttt tatctaaaca ttttgttagg aattttgttg ataataaagt
     3541 attttaaggt taagcaatag aaataataat ctgcctgatt atagatgata aactttttgt
     3601 ttttatctgg actgtgatat ttatagttct aaatggttta ttatttataa gtgttgaaag
     3661 agattgaaga aaatggcttc gtgacttgct ttcttcggtc tttttcgttt tattatcaat
     3721 ttgtaaacga tttacaattt gagtcaaatt atggtaaaat agtgtcatga gtaaaatgta
     3781 ctatgcagaa catcctgacg ctgctcacga cattcatgag ttgagagtgg acttgttggg
     3841 agaaaaaatg acttttttga cagatgcggg tgtttttagc aagaaaatgg ttgactttgg
     3901 aagtcaactc ttgctcaagt gtctggatgt caaccaagga gagacagtcc tagatgtagg
     3961 ctgtggctat ggtccattag gtttgtcctt ggtcaaggtt tacggagttc aggcgaccat
     4021 ggttgatatt aacactcgtg ccctggattt agctcagaga aatgctgaaa aaaataatgc
     4081 aaaagcgacg atatttcaat ctaatattta tgcaagagtt caagggcgat ttgaccatgt
     4141 catttccaat cctcctatcc gtgcgggcaa gcaagtcgtt catgaaatca tcgagaaaag
     4201 taaagatttc ttggaaattg gtggagattt gaccatcgtc atccagaaaa aacaaggagc
     4261 tccaagtgcc aagtctaaga tggaagatgt gtttggcaat tgtgaaatcc ttaaaaaaga
     4321 caagggatac tatatcctta gaagtgtgaa agaatgagag cagttgattt aatccaaaaa
     4381 aaacgagacg gtcaagaact gacttcaagt gaaattgaat ggctgataga aggctatgta
     4441 tcaggaactg ttcctgatta tcagatgtct gcctttgcta tggctgttta ttttaaagga
     4501 atgacgactc gagaaatctc tgatttaacg atgaatatgg ttaagactgg gcaagagttt
     4561 gacctgtcag ccattgatgg tgtgaaagtt gacaagcatt ctactggtgg tgtcggcgat
     4621 aaggtaacct tgattttagc tcctcttgtt gctagcttcg gtgtgcctgt agcaaaaatg
     4681 agtggtcgtg gtcttggcca tacaggcgga acaattgata aattggagtc cattaagggc
     4741 tatcaagtag aacgtagtca agaggatttt attcgtcagg ttcaggatat tggagtatct
     4801 gtcattgggc aatcagacca gctggtcaaa gcagataagc ttctctatgc tcttcgtgat
     4861 gtgaccgcaa ctgtcgacac gattcctttg attgcgagtt cggtgatgag caagaaaatt
     4921 gcggcagggg cggatgctat tttgctagac gtgactgtcg gtgagggtgc cttcatgaag
     4981 acggttgatg aggcgcgtga gttggctcaa actatggtag atcttggtaa ggttgttgga
     5041 cggaagacag tagcagtgat tacggatatg agccagcctt tgggacgagc gattggaaat
     5101 cgtctggaaa tccttgaagc attggagatt ttgcaaggtc aaggacgtca ggatattacc
     5161 cactttattt gtgaattggc tcaaattatg cttggtttgg caaatgttaa caaaactgtt
     5221 gaagaagttc gccaacatct tgaaaatggt caagcactgg ctaagtttga ggaaatggtg
     5281 caagcccaag gtggagactt ggaagacctc tatcgtcctg taaatgtagc tcatgtggtg
     5341 gaaatccctg ctcaggaaac gggtgtcatt tcagctcttc cagctatgga ctttggtctt
     5401 tatgccatga ggctgggtgc tggtcgtgca gttaagtctg atgtcttgga ctatgaaaca
     5461 ggaattgttt ttgaaaagaa gattggagac tccgttcaaa agggtgaaat tgtttcaaaa
     5521 gtatacacaa atgaaaaaat tccacctcaa ctagttacag atttccaaaa atgtgttaaa
     5581 ataagtgatg aagtgaaaaa aatccgtgaa attgtagaaa tcatctccta aatggaggga
     5641 aaaccgaaat gaaattaaat aaatatatag atcatacgct tttaaaacaa gatgcaaaga
     5701 aaaaacaaat tgatagtttg ttgtctgagg ctagagagta tgactttgcc agtgtttgcg
     5761 ttaatccgac ctgggttgaa catgctaaaa aaggacttga aggcacagat gttaaggttt
     5821 gcacagtagt aggtttccct ttgggagcaa caacttcagc cgtgaaagca tttgagacaa
     5881 aagaagctat ccaaaatggt gcagatgaga ttgatatggt gatcaatgtt ggagctctca
     5941 aatcaggtaa tttagccttg gttgagtcag atattcgcgc agtagtggaa gcaagtggtg
     6001 ataagttagt gaaagtcatt attgaagctt gccttctgac agaccaagaa aaaattgttg
     6061 tttgccaatt ggcccaaaaa gctggggctg actttgttaa aacatctact ggcttttcaa
     6121 ctggtggtgc tacgatagca gatgttagat taatgcgtga aacagttgga tctgatatgg
     6181 gagtcaaggc tgctggtgga gctcgttctt atgcagatgc tcttgccttt gtcgaagcag
     6241 gtgcgacccg tatcggaacg tcagctgggg tagctatttt aaaaggagaa ttggcagatg
     6301 gcgactactg agttgattga actggcaatt gaaaccagca aacatgccta tgtcccctat
     6361 tctcactttc ctatcggagc agttttagta gccaaagacg gaagtgttta cacgggagtg
     6421 aatatcgaaa atgctagcta tcctttgacc aattgcggtg agagaacagc tgtttttaag
     6481 gctatatctg aaggccaaag agaattttca gaattgattg tctatggtca aactgaaaaa
     6541 ccgatctcgc catgtggtgc ttgtcgccaa gtaatggtcg aattttttga acaagattta
     6601 aaagtgacct tagtcgcaaa agataaatcg acggtcgaga tgacggtcgg ggaattactt
     6661 ccatactctt ttacagactt aaactagtct gagtcgctct ctgagtggca cggtccttgt
     6721 ggccaaccaa tccatacttg caacatcgtt gcacatctta tttaggaggt tcagtaatga
     6781 acaagaaaca atggctaggc cttggtctag ttgcagtggc agcagttgga cttgctgcat
     6841 gtggtaaccg ctcttctcgt aacgcagctt catcttctga tgtgaagaca aaagcagcaa
     6901 tcgtcactga tactggtggt gttgatgaca aatcattcaa ccaatcagct tgggaaggtt
     6961 tgcaggcttg gggtaaagaa cacaatcttt caaaagataa cggtttcact tacttccaat
     7021 caacaagtga agctgactac gctaacaact tgcaacaagc ggctggaagt tacaacctaa
     7081 tctttggtgt tggttttgcc cttcataatg cagttgaaga agcagctaaa gaacacactg
     7141 acttgaacta tgtcttgatt gatgatgtga ttaaagacca aaagaatgtt gcgagcgtaa
     7201 ctttcgctga taatgagtca ggttaccttg caggtgtggc tgcagcaaaa acaactaaga
     7261 caaaacaagt tggttttgta ggtggtatcg aatctgaagt tatctctcgt tttgaagcag
     7321 gattcaaggc tggtgttgcg tcagtagacc catctatcaa agtccaagtt gactacgctg
     7381 gttcatttgg tgatgcagct aaaggtaaaa caattgcagc cgcacaatac gcagccggtg
     7441 cagatattgt ttaccaagta gctggtggta caggtgcagg tgtctttgca gaggcaaaat
     7501 ctctcaacga aagccgtcct gaaaatgaaa aagtttgggt tatcggtgtt gatcgtgacc
     7561 aagaagcaga aggtaaatac acttctaaag atggcaaaga atcaaacttt gttcttgtat
     7621 ctactttgaa acaagttggt acaactgtaa aagatatttc taacaaggca gaaaaaggag
     7681 aattccctgg cggtcaagtg atcgtttact cattgaagga taaaggggtt gacttggcag
     7741 taacaaacct ttcagaagaa ggtaaaaaag ctgtcgaaga tgcaaaagct aaaatccttg
     7801 atggaagcgt aaaagttcct gaaaaataat ggatggaagt catttcttag gaagcggcca
     7861 agggccgctt ttttaagagt tgagacaaag tcattttgtc tcagtaaagc ttgctactag
     7921 acaaactagc aagttttatt gaaataaaat aagactctga aaggaagagc acatggcaca
     7981 cgaaaatgtc attgagatgc gtgatattac caaggtgttt ggtggatttg ttgctaacga
     8041 caaaatcaac ttgcacctac gaaaaggtga aattcatgca cttttaggag aaaatggggc
     8101 tggtaagtcc acgctaatga acatgttagc aggccttctt gaaccaacta gtggtgaaat
     8161 cgcggtcaac ggtcaagttg tcaatctcga ctccccatct aaagcagcta gcttgggaat
     8221 cgggatggtt caccagcact ttatgttggt tgaagccttc acagtggctg aaaacatcat
     8281 tttaggtagt gaattgacta aaaatggtgt gctagatatc gctggagcta gcaaagaaat
     8341 caaggctctt tctgaacgtt atggcttagc tgttgaccct tctgccaagg tagcagatat
     8401 ctcagttgga gcccaacaac gtgtagaaat tttaaaaaca ctttataggg gggctgatat
     8461 ccttatcttt gacgaaccaa cggctgtttt gactccatca gaaattgatg agttgatggc
     8521 tattatgaaa aatcttgtca aagaaggaaa atcaattatc ttgattaccc acaaattgga
     8581 tgaaattcgc gcagtttctg accgtgttac agttatccgt cgtgggaaat caattgaaac
     8641 cgttgaaatt gcaggggcta ccaatgctga tttggcggaa atgatggtag gacgttctgt
     8701 ttcctttaaa acagagaagc aagcctctaa accaaaagaa gtggttttgt ctatcaaaga
     8761 tttggtggtc aatgaaaacc gtggtgttcc agctgttaaa aatctgtcct tggatgttcg
     8821 tgctggagag attgttggta ttgcggggat tgatggaaat ggtcagtctg aactgattca
     8881 agccattaca ggtcttcgta aggttgaatc tggtagcatt gagctaaaag gagattcaat
     8941 tgtaggcttg cacccacgtc agattacaga actaagtgtt gggcacgttc cagaagaccg
     9001 tcaccgtgat ggcttgattt tggaaatgat gatatctgaa aatattgccc ttcaaaccta
     9061 ctataaagaa ccacatagta aaaatggaat tttgaattat tcaaatatta cttcttatgc
     9121 taaaaagctg atggaagagt ttgatgttcg cgctgccagt gaattagttc ctgcagctgc
     9181 actctcagga ggaaatcaac aaaaagcaat tattgctcgt gaaattgatc gagatcctga
     9241 tctccttatc gttagccagc caactcgtgg gttggatgtc ggtgccattg agtatatcca
     9301 caaacgcttg attgaagagc gtgataatgg caaggctgtc cttgttgtca gctttgaatt
     9361 ggatgagatt ttaaacgtct cagaccgtat tgccgttatc cacgatggta agattcaagg
     9421 tattgtatca ccagaaacaa ccaataaaca aggacttggt gtcttgatgg ctggtggaaa
     9481 cttgggaaag gagaagagtg atgtctaaaa aattacaaca aatttcggtt cccttgattt
     9541 ctgtattcct aggaatttta ctcggagcca ttgtcatgtg gatcttcggt tatgatgcta
     9601 tttggggcta cgaagaattg ttctatacag cctttggcag tctgcgtggg attggagaaa
     9661 tcttccgtgc tatgggtcct ctggtcttga ttggtcttgg ttttgcggtt gccagtcgag
     9721 ctggtttctt taacgtcgga cttcctggtc aggctttggc aggttggatt ctcagtggtt
     9781 ggtttgccct gtcgcatcca gatatgcccc gtcccttgat gattctagca accatcgtga
     9841 ttgccttgat tgctggtggg attgtcggag cgattccagg tattcttagg gcctatctag
     9901 ggacgtcaga ggttattgta accatcatga tgaactacat tgtcttgtat gtagggaatg
     9961 cctttatcca tgctttccct aaagacttca tgcaaagtac agattcgacc attcgtgttg
    10021 gggctaatgc aacctatcag acaccttggt tggctgagtt gactggtaac tcacggatga
    10081 atattggtat tttctttgcc atcattgccg ttgcagttat ttggttcatg ctcaagaaaa
    10141 caactcttgg ttttgaaatc cgtgcagttg gtcttaatcc acatgcttca gaatatgctg
    10201 gtatttctgc caagcggact attatcctat ctatgattat ttcaggtgcc ttggcaggtc
    10261 ttggtggatc tgttgaaggt ttgggaacct tccagaacgt ctatgttcaa ggttcgtcat
    10321 tagctatcgg atttaacgga atggcggtta gtttgcttgc ggccaactca ccaattggta
    10381 tactctttgc agccttccta tttggcgttc tccaagttgg ggctcctggt atgaatgcgg
    10441 cgcaggtacc atctgagctt gtcagcattg taacagcgtc tattatcttc tttgtcagtg
    10501 ttcattacct tatcgaacgc tttgtcaaac cgaaaaaaca agttaaagga ggtaagtaaa
    10561 gatgtctatt ataaccttgc tccccctctt ggtgtcttct atgctgattt actcagcacc
    10621 tctcatcttt acaagtatcg gtggtgtttt ctctgaacgt ggtggtgtgg taaacgttgg
    10681 ccttgaagga attatggtta tgggtgcctt ttctggagtt gtctttaacc ttgaatttgc
    10741 agaacaattt ggagcagcaa ctccatggct atccttgctt gtagcaggat tggttggtag
    10801 tgttttctct atcatccacg cagcagcgac ggttcatttc cgtgcagacc atgttgtcag
    10861 cggtacggta ttgaacttga tggcgcctgc cttggctgtt ttcttagtta aagttcttta
    10921 taacaaagga caaaccgaca acctaagtca aacttttgga cgctttgatt tcccagtctt
    10981 ggcaaatatc ccagtgattg gtgatatctt cttcaagtca actagtctac ttggttatct
    11041 ggcgattgcc ttctcattcc ttgcttggtt tattctcttt aagactcaat ttggtcttcg
    11101 tctccgctct gtcggtgaac atcctcaagc agcggatacc ttgggaatca acgtctacaa
    11161 gatgagatat ttagggatta ttatttcagg ttttctaggt ggaattggcg gagcgattta
    11221 tgcgcaatca atctcagtta acttctcagt gacaactatt gttggacctg gatttatcgc
    11281 ccttgctgcg atgatctttg ggaaatggaa tccaatcggt gctatgcttt ctagtctctt
    11341 ctttggactt tcacaaagtt tggctgttat cggttctcaa ttgccgttcc tacaaggagt
    11401 gccagcggtt tatcttcaaa ttgcacctta tgttttgaca attcttgtct tagcagcctt
    11461 ctttggaaaa gcagtcgcac caaaagcaga tggtatcaac tacatcaaat caaaataagc
    11521 atacaaaaaa acgtcagtcc aatgactgaa ctgcccccca aaagttagac agaaaaaatc
    11581 taacttttgg ggtgttttta ttatgaaatt aacttatgat gataaagttc agatctatga
    11641 acttagaaaa caaggatata gcttagagaa gctttcaaat aaatttggga taaacaattc
    11701 taatcttagg tacatgatta aattgattga tcgttacgga atagagttcg tcaaaaaagg
    11761 aaaaaatcgt tactattctc ctgatttaaa acaagaaatg attaataaag tctgacatga
    11821 aggctggact aaagacagag tttctcttga atacggtctc ccaagtcgta cgatacttct
    11881 taactggcta gcacaataca gaaaaaaacg ggtatactat tgttgagaaa acaagaggga
    11941 gagtacctaa aatgggacgt aagccaaaaa agagacctga agagaggaca gaattagaac
    12001 atcttcaagc agaaaatgag tacctgagag cggagaatgc catcctaaaa aagttaagag
    12061 aactccgatt gaaggaggaa aaagagaaag aagaaagaca gaaattgttc aagaattaat
    12121 gactgagttt tcgttagata ttcttctaaa agccattaaa ctagctcgtt cgacctacta
    12181 ctatcacttg aaacagctag acaaaccaga taaggaccaa gagcttaaag ctgaaattca
    12241 atccattttt atcgaacaca agggaaatta tgcttatcgt cggatttatt tagaactaag
    12301 aaatcgtggt tatctggtaa atcataaaag agttcaaggc ttgatgaaag tactcaattt
    12361 acaagctaaa atgcgacaga aacgaaaata ttcttctcat aaaggagacg ttggtaagaa
    12421 agcagagaat ctcattcaag gccaatttga aggctctaaa acaatggaac agtgctacac
    12481 agatgtgact gaatttgcca ttccagtaag tactcaaaag ctttacttat caccagtttt
    12541 agatggtttt aacagcgaaa ttatcgccta taatctttca acttcaccca acttagaaca
    12601 agtacaaaca atgttggaac aggcattcac agagaagcac tacgagaata cgattctcca
    12661 tagtgaccaa ggctggcaat atcaacacga ttcttatcat cagtttcttg agggtaaggg
    12721 aattcaagca tccatgtcac gtaagggtaa cagcccagac aatggtatga tggagtcctt
    12781 ctttgggatt ctgaaatcgg aaatgtttta cggttatgag aagtcgtttc agtcgcttaa
    12841 gcaattggaa caagccattg tagactatat tgattactac aacaataaac gaattaaggt
    12901 aaaactaaaa ggacttagcc ctgtgcaata cagaactaaa tccttcggat aaattaattg
    12961 tctaactttt tggggtcagt acagaactgg cgttttattt tttaggatct tgatgggtta
    13021 ggttcaatcc ccaagggacc aaattttcag ttttattttt gatacgagct atattgtcct
    13081 tatgacgaat gataatcaaa ctagcaagtg ctaagataat agcgatgaag agagagtcat
    13141 agttactcag gataaaacca aaaagtggaa agagcagaac cccgataaca gccgcgatcg
    13201 atgctgtgac actagacagt gaaatcatac tgccaagata gagagctcca aagaagataa
    13261 tcgcaaggta gagacagaag ataggcgcaa atccgaaaat cactccagca ctggttgcga
    13321 cagccttacc acctttaaat cctgcaaaga tagggaaggt atggccgata acagccaaaa
    13381 gtccaaagat gagaggagaa acgccttgta gatgaaaaat aatcggaagc agcgttgcta
    13441 gggttccttt gaaaaagtca atcacaaagg ttgccatacc agctttctta cctaaaatgc
    13501 ggaaggtgtt ggtcgttcca gtgttaccag aaccatgctc gcgtagattg atttgaaaga
    13561 atacttgtcc aatccagaga ccagatggaa tcgaacccag cagataggct aggattaata
    13621 aaactattgt aatcatactc ctattatatc atgaattggg aaagaaaagc agagaatctc
    13681 tgctgaaatt gtcacatcgg agaaagaaaa attttgcaaa atccttggaa aacctgtaga
    13741 atagtaaaga tgaacgaata ggaggttcct tgtgtcaaaa aaggaaatca atattaacaa
    13801 ttataatgat gatgctattc aggtgctaga agggttggat gcggtccgaa aacgtccagg
    13861 gatgtatatt ggatcgaccg atggcgctgg tcttcatcac ctagtttggg aaatcgttga
    13921 taatgcagtc gatgaagcct tgtctgggtt tggtgatcgt attgatgtaa ctatcaataa
    13981 agacggtagt ctaacggttc aagaccatgg acgtgggatg ccgacaggta tgcacgctat
    14041 gggaattcca actgttgagg ttatctttac cattcttcat gccggaggga aattcggtca
    14101 aggtggctat aagacatcag gtggacttca cggagtgggt tcttccgttg ttaacgccct
    14161 ttctagctgg ttagaagttg aaattacccg tgatggcgca gtttacaagc aacgttttga
    14221 aaatggtgga aaacctgtca cgactttgaa gaaaatcggt acagcaccca agtctaaaac
    14281 aggcaccaaa gttactttta tgcctgacgc gactatcttt tctacgacag atttcaagta
    14341 caataccatt tcagagcgcc ttaatgaatc agcctttctc ttgaaaaatg tgaccttgtc
    14401 tttaacggac aagcgaacag atgaagcgat tgagttccac tatgagaatg gagtacaaga
    14461 ttttgtttct tatctcaacg aagataagga aatcttgacg ccagttcttt actttgaagg
    14521 ggaagacaat ggttttcaag tggaagtagc cctccagtac aatgacggat tctcagataa
    14581 cattctatcc tttgtcaata acgttcgcac caaggacggt ggaacgcacg agacaggact
    14641 caagtctgcc attaccaagg tcatgaatga ctatgcacgt aaaacaggtc ttctcaagga
    14701 aaaagataaa aaccttgaag gttcagacta tcgtgaggga ctagcggccg ttctttctat
    14761 cttagttcct gaagaacact tgcagtttga aggacagacc aaggataaac taggaagccc
    14821 cctagctcgc ccagttgtgg atggaatagt ggctgataag ttgacctttt tccttatgga
    14881 aaatggggaa ttagcttcta acctcatccg caaggctatc aaggcccgtg atgctcgtga
    14941 agcagcacgt aaggcgcgtg atgagagccg aaatgggaag aaaaacaaga aagataaggg
    15001 cttgttgtct gggaaattga ccccagccca atctaagaat cctgctaaga atgaactcta
    15061 tctagttgag ggggactctg ccggtggttc tgccaaacaa ggtcgtgacc gcaagttcca
    15121 ggctattcta cctcttcgtg gtaaggttgt caatacagcc aaggccaaga tggcggatat
    15181 cctcaaaaat gaagagatca ataccatgat ttataccatt ggtgcgggtg ttggagcaga
    15241 cttctctatt gaagatgcca actatgataa gatcattatc atgaccgatg cggataccga
    15301 cggtgcccat atccagacct tgctcttgac atttttctac cgttacatgc gtccgctagt
    15361 cgaggcaggt catgtctata ttgccctccc acctctttac aagatgtcca aaggtaaagg
    15421 caagaaagaa gaagtggcct acgcttggac ggacggagaa ctagaagaac tccgtaaaca
    15481 gttcggtaaa ggcgctaccc tccaacgata caaaggactt ggtgagatga atgcggacca
    15541 gctctgggaa acaaccatga acccagaaac acgtaccctc atccgtgtca caattgaaga
    15601 tttagcgcgc gccgaacgcc gcgtcaatgt tctcatggga gataaggtag aaccacgccg
    15661 taaatggatt gaagataatg tcaagtttac gctagaagaa gcgacagtgt tttaatgaaa
    15721 gaaaataata tgttagtaaa ctggaaatta gagtcggatg tgaatgacta tgtgaaaaag
    15781 cagtttgaaa atcttggttt gaaaaaattg caggattatt aatgaagaat ctgctatgag
    15841 tgcttatctc aaagaggcgt ttaagggagc ggctaagaca caaactaaga ctaattttgg
    15901 aaaaccatat tttcatattg aaaaatacaa acaggatagt ttggttactt atcgtaactg
    15961 aacacgggac gaattcccgt aaaatatctt ttactgcata aaaacctact ctacattctt
    16021 tgaaaggagt tgaacacgcc ctagatactg tgtgaaaaag ataaattctc ttgtgagttt
    16081 gcttacttca agaattttct attttcactt ggtattttat gggctttgta tcttatgtct
    16141 aacattcaaa acatgtccct ggaggacatc atgggagagc gctttggtcg ctactccaag
    16201 tacattattc aagaccgggc tttgccagat attcgtgatg ggttgaagcc ggttcagcgc
    16261 cgtattcttt attctatgaa taaggatagc aatacttttg acaagagcta ccgtaagtcg
    16321 gccaagtcag tcgggaacat catggggaat ttccacccac acggggattc ttctatctat
    16381 gatgccatgg ttcgtatgtc acagaactgg aaaaatcgtg agattctagt tgaaatgcac
    16441 ggtaataacg gttctatgga cggagatcct cctgcggcta tgcgttatac tgaggcacgt
    16501 ttgtctgaaa ttgcaggcta ccttcttcag gatatcgaga aaaagacagt tccttttgca
    16561 tggaactttg acgatacgga gaaagaacca acggtcttgc cagcagcctt tccaaacctc
    16621 ttggtcaatg gttcgactgg gatttcggct ggttatgcca cagacattcc tccccataat
    16681 ttagctgagg tcatagatgc tgcagtttac atgattgacc acccaactgc aaagattgat
    16741 aaactcatgg aattcttgcc tggaccagac ttccctacag gggctattat tcagggtcgt
    16801 gatgaaatca agaaagctta tgagactggg aaagggcgcg tggttgttcg ttccaagact
    16861 gaaattgaaa agctaaaagg tggtaaggaa caaatcgtta ttactgagat tccttatgaa
    16921 atcaataagg ccaatctagt caagaaaatc gatgatgttc gtgttaataa caaggtagct
    16981 gggattgctg aggttcgtga tgagtctgac cgtgatggtc ttcgtatcgc tatcgaactt
    17041 aagaaagacg ctaatactga gcttgttctc aactacttat ttaagtacac cgacctacaa
    17101 atcaactaca actttaatat ggtggcgatt gacaatttca cacctcgtca ggttgggatt
    17161 gttccaatcc tgtctagcta catcgctcac cgtcgagaag tgattttggc gcgttcacgc
    17221 tttgacaaag aaaaggctga gaaacgtctc catatcgtcg aaggtttgat tcgtgtgatt
    17281 tcgattttgg atgaagtcat tgctcttatc cgtgcttctg agaataaggc ggacgccaag
    17341 gaaaacctca aagttagcta tgattttacg gaagaacagg ctgaggctat cgtaactttg
    17401 caactgtacc gtttgaccaa taccgatgtg gttgtcttgc aggaagaaga agcagagctt
    17461 cgtgagaaga ttgctatgct ggtggctatt atcggtgatg aaaggactat gtacaatctc
    17521 atgaagaaag aacttcgtga ggtcaagaag aaatttgcaa ctcctcgttt gagttcttta
    17581 gaagacactg cgaaagcaat tgagattgat acagctagtc ttatcgctga ggaagatacc
    17641 tacgtcagcg tgaccaaggc aggttacatc aagcgtacca gtccacgttc ctttgcggct
    17701 tccaccttgg aagaaattgg caagcgtgat gatgaccgtt tgatttttgt tcaatctgcc
    17761 aagacaaccc agcacctctt gatgttcaca agtcttggaa atgtcatcta cagaccaatc
    17821 catgagttgg cagatattcg ttggaaggac atcggagagc atctgagcca aaccatcaca
    17881 aactttgaaa cgaatgaagc aatcctttat gtggaagtac tggatcagtt tgacgatgcg
    17941 acaacctact ttgcagcgac tcgccttggt caaatcaaac gggtagagcg aaaagaattc
    18001 actccatggc ggacctatag atctaagtct gtcaagtatg ctaagctcaa agacgataca
    18061 gatcagattg tagcagtggc tccgattaaa ctagatgatg ttgtcttggt tagtcaaaat
    18121 ggttatgccc tgcgtttcaa tatcgaagag gttccggttg tcggtgctaa ggcagcaggt
    18181 gtcaaggcta tgaatttgaa agaagatgat gtcctccaat ctggctttat ctgtaatact
    18241 tcgtccttct acctcttgac ccagcgtgga agcttgaaac gtgtttccat tgaggaaatt
    18301 ctagcaacca gccgtgccaa acgaggatta caagtcttgc gtgagttgaa aaacaaaccg
    18361 catcgtgtct tcttggcagg agcagttgca gagcaaggat ttgttggcga tttcttcagt
    18421 acggaagtgg atgtgaacga ccaaactctg cttgtccaat ccaataaagg aacaatctat
    18481 gaaagccgat tgcaagactt gaacttgtca gaacgcacta gcaatggaag cttcatttct
    18541 gacacgattt cagatgaaga agtttttgac gcttatcttc aggaagtagt tactgaagat
    18601 aaataagtga aatgaagaat cagttctaag agctggtttt tattggagaa attttctgaa
    18661 aattacaaaa tatacttgct attttagaaa aatagtgtag aatataagaa ataggttttt
    18721 agaataagga gtggaatatg acagtaacga ttgattggga aaacctcggt ttttcctata
    18781 tgaaattacc ttatcgctat cttgctcatt tcaaaaatgg acaatgggat caaggagagc
    18841 ttacagagga tgcaactttg catatttcag agtcttctcc aagtcttcac tatggacaac
    18901 aagcatttga aggtttgaaa gcttatcgta ctaaggatgg cagtgttcaa ctgttccgtc
    18961 ctgatgaaaa tgctaaacgc ctgcaacgta catgtgaccg tctcttgatg ccacaagttc
    19021 cgacagacat gtttgtagaa gcttgtaaag cagttgtccg tgcgaatgaa gaatacgtac
    19081 caccatacgg aataggtgga accttatatc ttcgccctct tttgattggt gtcggagata
    19141 ttatcggggt aaaaccggca gaagaataca ttttcaccat ctttgctatg ccagttggaa
    19201 attactttaa aggtggtttg gtcccaacca acttcttgat tcaggatgag tacgaccgtg
    19261 cagcaccaaa tggtacaggt gcggctaagg ttggtggaaa ctatgctgca agtctcttac
    19321 caggaaaaat ggccaagtca cgtcatttct cagatgttat ctatctggac ccatcaactc
    19381 atacaaagat tgaagaagtc ggatcagcta acttctttgg aattacagct gataatgaat
    19441 ttgtaacacc attgagtcca tctatcttgc catctattac caagtattcc ttgctttatt
    19501 tggcagaaca tcgcttggga ttaactccta ttgagggtga tgttccaatt gataatcttg
    19561 accgttttgt agaggcaggt gcctgtggta cagcagcggt tatttctcca attggaggta
    19621 ttcaacatgg tgatgatttc catgtattct atagtgaaac agaagtaggt cctgtgacgc
    19681 gtaaattata taatgaattg acgggtattc agtttggcga tattgaagcg ccagaaggtt
    19741 ggattgtaaa agtagattaa aataaaccaa aggagatttt ttatgaaata gaaaaagtgg
    19801 ctcttaacag caggagtggt cctgagcacg tcagctattt tagtggcttg tggaaaaact
    19861 gataaagaag cagatgcacc gacaacattt tcttatgtct atgcagtaga tccagcatca
    19921 ttgggctaca gtatagcgac tcgaacatcg acgacagacg ttattggaaa tgttattgat
    19981 ggtttgatgg aaaatgataa atacggcaat gttgctcctt ctcaaaaaga ctatgatttg
    20041 aatagtacag gatgggctcc aagctatcaa gatccagcgt cttacttgaa tattatggat
    20101 ccaaaatctg gttctgccat gaaacacctt ggcattacga aaggaaaaga taaggatgtt
    20161 gtagctaaac ctggtttgga taaatataag aaattgttag aagatgctgt ttctgagacc
    20221 actgacctag agaagagata tgaaaaatat gccaaagctc aagcttggtc gacagatagt
    20281 tcattattga tgccaacagc ttcatctggt ggttctccag ttgtaagtaa cgtagtacca
    20341 ttctcaaaac catactcaca agttggtatt aagggggaac catatatctt taaaggaatg
    20401 aaattgcaaa aagatattgt tacaacaaaa gaatataacg aggtttttaa aaaatggcaa
    20461 aaagaaaaat tggaatccaa tagcaaatac caaaaagaac tagaaaaata cattaaataa
    20521 ggaatggtat tgatcttgat aaaattttta aaatactgtc attttgaata taaaggagtt
    20581 tgatatggag tggattagat taataggaat agcaatcatt gttgtgggtt ttattttaaa
    20641 atttgataca attgcaacag tagtcttagc tggtttggtt acagctttag tttcaggtgt
    20701 ttctctcgtt gaatttttgg agattttggg aaaagaattt agcaatcagc gagtgctcac
    20761 gatttttatg gttaccttgc ctcttgtggg gctgtcagaa acctttggac tcaagcaacg
    20821 atcaatcgat ttgattcgaa agattaaagg tctgacagtt ggaaacttct atacagttta
    20881 tttctttatt cgagagttag ctggtttctt ttcaattcgt ctaggaggac accctcagtt
    20941 tgtcagacct ttggttcaac ctatgggaga agcagctgca gagtctcaat taggtagaaa
    21001 gttaacagag gttgaagatg agacaataaa agcgcgtgcg gctgcgaatg aaaattttgg
    21061 gaatttcttt gctcaaaata cgtttgtagg tgctggggga gtcctcttga tagggggaac
    21121 attagatcag ttaggctatg aaagcaatta tgcagggatt gcttctacat ctattattgt
    21181 tgctgttata acacttattg tagtggggat ttacaattat ttatttgata aaaaattgat
    21241 atcaaaaaag actaggggag gagaacaaaa atgacagagt tggcaaagca actattagag
    21301 ttgacctata ttgtgattgg ttgtcaattt ctccatacag cctattgtag ttataaagat
    21361 aaaacaaacc cagttcgact tgggacatct gtattttgga ctctattgtc tattacgttt
    21421 ataggtggtt cctatatgcc aaatatgagt attggtatta ttgtaatcct attatcgctg
    21481 ttaacattgt ttaagcaagt ccgtatcgga accttgccat ccttagatga aatgaaagcc
    21541 aatattgaat ctaacaggtt gaaaaataaa atttttattc cagttatgct gatggcaata
    21601 cttgcgttgg tcttagcgca aatgattcca gaatttagca agatttcgat tagccttgcc
    21661 gccttgtttg ctacaatttc tgttcttgtg attaccaata gtcaccctaa gagtctgtta
    21721 tcagaaaata atcgaatgac tcagcaagtt tcaacaagtg ggattgttcc tcaattatta
    21781 ggggctttgg gggctatttt tactgtagca ggtgttggtg atgttatctc tcatctgatt
    21841 agcggtattg ttccttcaga tagtcgcttt ataggagttt tggcttatgt tcttggaatg
    21901 gttctattca caatgattat gggaaatgct tttgcagcat tcaccgttat tacagcaggt
    21961 gttggagttc cctttgtatt tgctctggga gctaatccaa ttgtggctgg tgctcttgcc
    22021 atgacagcag gttattgtgg gaccttattg accccaatgg ctgctaattt taacgctcta
    22081 ccagcagcat tgatggatat gaaagatcag aatggcgtta taaaggctca agcaggtgtt
    22141 gctctagtaa tgattgttat tcacatattc ttaatgtact ttctcgcatt ttagtaaagg
    22201 aaaataaaat gaaaatattg gttacaggtt ttaatccttt tggaggtgaa aagattaatc
    22261 cagctttgga ggctgtaaaa ttattaccat ctgagattaa tggggctgaa gttcgctggg
    22321 tagaaattcc aacggttttt tataagtcgt cagaagtttt agaggcagaa atattacgat
    22381 atcaaccaga tgctgtactt tgtattggac aagcaggcgg caggaccggc ttaacacctg
    22441 aacgagtggc tattaatcaa gatgatgctc gcatacctga taacgaaggc aatcaaccaa
    22501 ttgatacacc gattcgtatt gatggagcat cggcctattt tagtagttta cctatcaaag
    22561 cgatggtaca agctatcaaa aaacagggac ttccggcagt tgtatccaat agtgcaggaa
    22621 cctttgtttg caatcatttg atgtaccaag ctctttattt agtggataaa aaattcccta
    22681 atatgagagc aggtttcatg catattccat atatgatgga acaagtagta aataagccga
    22741 atactgcagg aatgagtcta tgtgatattg taagaggcat agaggtagct attgaagcta
    22801 ttgtagacta caaagataag gatttgcagt tagtaggcgg tgagactcac tgataaccta
    22861 aaaaggatag tcaattatgc ttgtttacta actattaact atgctaaatc aattgaggtt
    22921 gtttacataa aactctatat cagagaagcc tgatatagag ttttttcttg ctagttttag
    22981 gattttcttg taaaatagaa aaagtgaaga gaggtatgaa atgagcaaga aagataaaaa
    23041 aatcgaaatt caagtagcgg atgccaaagt taatgttggt aaagacagtt ttgaaggtta
    23101 tacattgact atcggtaaaa aagttatcgg agaaattgcc gaattagacg gacaatttgc
    23161 cattataaag aatgggaatg tcgatagttt ttataaaaaa ttggaaaaag ctgtggaaat
    23221 tttgattgaa aattataatt tagcaaaata agtcttgttt ttttgaaatt ttcatgatat
    23281 aatagtccat gttgattgta ggagagatag cgaagaggct aaacgcggcg gactgtaaat
    23341 ccgctccttc gggttcgggg gttcgaatcc ctctctctcc atttcattaa tggggtatag
    23401 ccaagcggta aggcaaggga ctttgactcc ctcatgcgtt ggttcgaatc cagctacccc
    23461 agttcttagg taataatcaa gatagaaagc aaaatatctt agggtatttt atttttataa
    23521 ttgaaagacg tgaatgatat gaacatgtcc ttgcgggtgc ttaggaaaaa aattataagt
    23581 atgtcaagtt taagaaaaac ttgattgttg gaggattttt tagatgaacg aatttgaaga
    23641 tttgctaaat agcgttagtc aagttgagac tggtgatgtt gttagtgctg aagtattgac
    23701 agttgatgcg actcaagcta acgttgcaat ctctggaact ggtgttgaag gtgtcttgac
    23761 tcttcgcgaa ttgacaaacg atcgtgatgc agatatcaat gactttgtta aagtaggaga
    23821 agtattggat gttcttgtac ttcgtcaagt agttggtaaa gatactgata cagttacata
    23881 ccttgtatct aaaaaacgcc ttgaagctcg caaagcatgg gacaaacttg ttggtcgcga
    23941 agaagaagtt gttactgtta aaggaacgcg tgccgttaaa ggtggacttt cagtagaatt
    24001 tgaaggtgtt cgtggattta tcccagcttc aatgttggat actcgtttcg tacgtaacgc
    24061 tgagcgtttt gtaggtcaag aatttgatac taaaatcaaa gaagttaacg ctaaagaaaa
    24121 ccgcttcatc ctttcacgtc gtgaagttgt tgaagcagct actgcagcag ctcgcgctga
    24181 agtattcggt aaattggctg ttggtgatgt tgtaactggt aaagttgctc gtatcacaag
    24241 cttcggcgct ttcatcgacc ttggtggtgt tgacggattg gttcacttga ctgaattgtc
    24301 acatgaacgt aacgtatcac caaaatcagt tgtaactgtt ggtgaagaaa ttgaagtgaa
    24361 aatccttgat cttaacgaag aagaaggacg tgtatcactt tcacttaaag caacagtacc
    24421 aggaccatgg gatggcgttg agcaaaaatt ggctaaaggt gatgtagtag aaggaacagt
    24481 taaacgtttg actgacttcg gtgcatttgt tgaagtattg ccaggtatcg atggacttgt
    24541 tcacgtatca caaatttcac acaaacggat tgaaaatcca aaagaagctc ttaaagttgg
    24601 tcaagaagtt caagttaaag ttcttgaagt taacgcagat gcagaacgcg tgtcactttc
    24661 tattaaagct cttgaagaac gtccagccca agaagaagga caaaaagaag aaaaacgtgc
    24721 tgctcgtcca cgtcgtccaa gacgtcaaga aaagcgtgat ttcgaacttc cagaaacaca
    24781 aacaggattt tcaatggctg atttgtttgg tgatatcgaa ctttaatcaa attgaaaatt
    24841 cacaaaatcc tttgtttact aaacaaggga tttttctggc tctttgtcaa ctgtagtggg
    24901 ttgaagaaaa gctaagcttg agaaaggaca aatttcgtcc tttctttttt gatgttcaaa
    24961 gcgataaaaa tccgtttttt gaagttttca aagtt
//
LOCUS       DBERPV010000030        24189 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.30, whole genome shotgun sequence.
ACCESSION   DBERPV010000030 DBERPV010000000
VERSION     DBERPV010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 24189)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24189)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24189
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.30"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(98..331)
                     /locus_tag="ACL8C7_001524"
     CDS             complement(98..331)
                     /locus_tag="ACL8C7_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGS1395695.1"
                     /translation="MTKKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            complement(337..1329)
                     /gene="plsX"
                     /locus_tag="ACL8C7_001525"
     CDS             complement(337..1329)
                     /gene="plsX"
                     /locus_tag="ACL8C7_001525"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HGS1395696.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YSKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLSGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(1326..2096)
                     /gene="recO"
                     /locus_tag="ACL8C7_001526"
     CDS             complement(1326..2096)
                     /gene="recO"
                     /locus_tag="ACL8C7_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HGS1395697.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(2093..3262)
                     /locus_tag="ACL8C7_001527"
     CDS             complement(2093..3262)
                     /locus_tag="ACL8C7_001527"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGS1395698.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQVISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            3411..4421
                     /locus_tag="ACL8C7_001528"
     CDS             3411..4421
                     /locus_tag="ACL8C7_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HGS1395699.1"
                     /translation="MSFLSKNGAGILVCLLISIVSWYLGGFFPVIGAPVFAIFMGMLL
                     HPFLSSYKQLDVGLTFSSKKLLQYAVILLGFGLNISQVFAVGQSSLPVILSTISIALI
                     VAYLFQRFFALDTKLATLIGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNDGFALFAGTAVNDTSSVTATASAWDSLYQTNTLESATIVKLT
                     RTLAIIPITLFLSYWQSREQKNKQGLQLKKVFPLFILHFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIIMAMSAIGLKTNLVAMVKSSGKSIVLGAVCWIAIILTSLGMQTLIG
                     IF"
     gene            complement(4649..5086)
                     /locus_tag="ACL8C7_001529"
     CDS             complement(4649..5086)
                     /locus_tag="ACL8C7_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HGS1395700.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(5171..7804)
                     /gene="polA"
                     /locus_tag="ACL8C7_001530"
     CDS             complement(5171..7804)
                     /gene="polA"
                     /locus_tag="ACL8C7_001530"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HGS1395701.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAKGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCEDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQPYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYLQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            8060..8967
                     /locus_tag="ACL8C7_001531"
                     /pseudo
     CDS             8060..8967
                     /locus_tag="ACL8C7_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603324.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
     gene            9094..9375
                     /locus_tag="ACL8C7_001532"
                     /pseudo
     CDS             9094..9375
                     /locus_tag="ACL8C7_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436408.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(9509..10477)
                     /locus_tag="ACL8C7_001533"
     CDS             complement(9509..10477)
                     /locus_tag="ACL8C7_001533"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGS1395702.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(10622..11436)
                     /locus_tag="ACL8C7_001534"
                     /pseudo
     CDS             complement(10622..11436)
                     /locus_tag="ACL8C7_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
     gene            complement(11461..11958)
                     /locus_tag="ACL8C7_001535"
     CDS             complement(11461..11958)
                     /locus_tag="ACL8C7_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-class carbonic anhydrase"
                     /protein_id="HGS1395703.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(12031..13395)
                     /gene="radA"
                     /locus_tag="ACL8C7_001536"
     CDS             complement(12031..13395)
                     /gene="radA"
                     /locus_tag="ACL8C7_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016893792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HGS1395704.1"
                     /translation="MIAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEIEVAEVK
                     NARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGK
                     STLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEV
                     ERIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKE
                     GTLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLN
                     PSQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASL
                     IMAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVG
                     ELGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLK
                     KVFA"
     gene            complement(13406..13921)
                     /locus_tag="ACL8C7_001537"
     CDS             complement(13406..13921)
                     /locus_tag="ACL8C7_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGS1395705.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSDMGRQQVQKLSK
                     NPLLSSAEIIVSSAVARALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENRGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(13923..14366)
                     /locus_tag="ACL8C7_001538"
     CDS             complement(13923..14366)
                     /locus_tag="ACL8C7_001538"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HGS1395706.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(14651..15016)
                     /locus_tag="ACL8C7_001539"
                     /pseudo
     CDS             complement(14651..15016)
                     /locus_tag="ACL8C7_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
     gene            15036..15203
                     /locus_tag="ACL8C7_001540"
     CDS             15036..15203
                     /locus_tag="ACL8C7_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzC family protein"
                     /protein_id="HGS1395707.1"
                     /translation="MANTPIKPGTDNQKPGRYVEVGPRGGKVTNGHTATIGKGDRLPP
                     TSAKGNGWKKV"
     gene            complement(15358..15561)
                     /locus_tag="ACL8C7_001541"
     CDS             complement(15358..15561)
                     /locus_tag="ACL8C7_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395708.1"
                     /translation="MRPKRYPYSGQKESTFVKADPELVEKLLRNTSFLECLQKKPINF
                     QIDSEEFKRLSYEAIHDTSQVTQ"
     gene            complement(15584..15775)
                     /locus_tag="ACL8C7_001542"
     CDS             complement(15584..15775)
                     /locus_tag="ACL8C7_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HGS1395709.1"
                     /translation="MPDIANGRERVIAFLKEKGIKKATLAVAYGFKRQEVTNILSGTT
                     KGPRANSFILQVIEDYGIE"
     gene            15840..16079
                     /locus_tag="ACL8C7_001543"
     CDS             15840..16079
                     /locus_tag="ACL8C7_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000142894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395710.1"
                     /translation="MTFKEYLLKASKRDIYDDGKDFDFETIFAREILRYAHDSELETK
                     TGFFRHLEIMNADSWFVELARSIYQDFEKSISDSH"
     gene            16493..16861
                     /locus_tag="ACL8C7_001544"
     CDS             16493..16861
                     /locus_tag="ACL8C7_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS1395711.1"
                     /translation="MFETFEKIKELAKKRGKALGQVEEDLGYGRNTLYKIKNSTPNAE
                     RIAEIANYFNVSTDYLLGRTDNPAIAGSDEFAQVNGQIIDLRKAAANTMLFDGKPLNE
                     DDIDFITSVLSAHFKSKGER"
     gene            16861..17094
                     /locus_tag="ACL8C7_001545"
     CDS             16861..17094
                     /locus_tag="ACL8C7_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395712.1"
                     /translation="MTITINFTEKNSYITDYLNKHGIDTTTMDFDDFMALMEDIEDAR
                     AADQAYMEYLADPATYTMDEVLDELGLTREDIA"
     gene            17094..17357
                     /locus_tag="ACL8C7_001546"
     CDS             17094..17357
                     /locus_tag="ACL8C7_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HGS1395713.1"
                     /translation="MYRLDIDKKALKQLKKLDTPTRKQILSWLAKNIENTTNPRQHGK
                     ALKANLAGYWRYRVENYRIICDIQDDKLVVLAVEIAHRRDVYK"
     gene            17370..17750
                     /locus_tag="ACL8C7_001547"
     CDS             17370..17750
                     /locus_tag="ACL8C7_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HGS1395714.1"
                     /translation="MTLAKLCEEYQVELCLFDGSNWHNSGFYNPDTNVLAIDHNLTPE
                     QQIQVALHELGHKDHTRSEHQNARLRCENEADRNMIHHLVKDALENLDDPTEFDYLKF
                     MSYYNLKTMTNEIMVKEEYLALVN"
     gene            17767..18837
                     /locus_tag="ACL8C7_001548"
     CDS             17767..18837
                     /locus_tag="ACL8C7_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease"
                     /protein_id="HGS1395715.1"
                     /translation="MEIDKVKADLKQVGKRVADLSQSITNEEQTKNAFIMPFFQALGY
                     DIFNPLEFVPEFTADVGIKKGEKVDYAIILDGEPQILIECKSITENLTKHDSQLFRYF
                     VTTKSKFGILTNGREYKFFTDLDEPNKMDTTPFLTIDVTDIKENQFTEIIKFHKENFD
                     IDNIVSSASELKYLNNLKAFLTENITTPSDSFLRYLTSEIYEGRVTQNILTTFSPIIV
                     KGFNQFITERVNEKLSAALNTSVETKVTTDIPKVEAEAEEIVEVTDEIITTPAELEVY
                     TVVKMLARDVVSPERVFYRDNRSYFNVLVDDNIKKWVLRYRSNSKKSTIEIRDKGIFP
                     VSTPLEVANYANEILEVIKKFS"
     gene            18898..20034
                     /locus_tag="ACL8C7_001549"
     CDS             18898..20034
                     /locus_tag="ACL8C7_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGS1395716.1"
                     /translation="MEELPNGKYKFFERYKDPYTEKLKKVSVTMEKKTPQARNQAAIL
                     LQEKIKQKLGEKQHSVSNITFEKLYEEFEENWKHGVKNSTVYASKNVKKEILKQIEGD
                     YLVRNIDRRLLQKVIDQLLQDGRSHNYVSKIKFKLNQIMKFAIRMNYIDTNEMLFVET
                     PRKVITSDELKKKNTKYLDQKEFKLFIQNLKDEALCDYRITKYIRIAKVLFLTGMRYG
                     ELAALNYKEDIDFSKKTIHIKHTYDFRQKERTTPKTIKSDRVITAPQKVLDIIKEQII
                     ENATNGFDTDFIFINTLGEPITNARVICALKRHGQKIGIEKNITTHTFRHSHISLLAE
                     LGIPLTAIMDRVGHSDSKTTLEIYSHVTQKMVSDISSKLDKIKF"
     gene            complement(20117..20210)
                     /gene="ffs"
                     /locus_tag="ACL8C7_001550"
     ncRNA           complement(20117..20210)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACL8C7_001550"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(20243..20710)
                     /gene="tadA"
                     /locus_tag="ACL8C7_001551"
     CDS             complement(20243..20710)
                     /gene="tadA"
                     /locus_tag="ACL8C7_001551"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HGS1395717.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYNILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(20911..22197)
                     /locus_tag="ACL8C7_001552"
     CDS             complement(20911..22197)
                     /locus_tag="ACL8C7_001552"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HGS1395718.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(22428..22664)
                     /gene="comW"
                     /locus_tag="ACL8C7_001553"
     CDS             complement(22428..22664)
                     /gene="comW"
                     /locus_tag="ACL8C7_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma(X)-activator ComW"
                     /protein_id="HGS1395719.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            22906..23703
                     /locus_tag="ACL8C7_001554"
                     /pseudo
     CDS             22906..23703
                     /locus_tag="ACL8C7_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(23738..23947)
                     /locus_tag="ACL8C7_001555"
                     /pseudo
     CDS             complement(23738..23947)
                     /locus_tag="ACL8C7_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(24113..24186)
                     /locus_tag="ACL8C7_001556"
     tRNA            complement(24113..24186)
                     /locus_tag="ACL8C7_001556"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(24150..24152),aa:Asn,seq:gtt)
BASE COUNT         7593 a         5625 c         4160 g         6811 t
ORIGIN      
        1 gcccttgata accactgtca gccaagattt taccagcttg tccgatattt ctaatttcta
       61 aaaaccatct acttccgttg acttggaact ccgattgcta ttttccttga atgattttaa
      121 ccacatctcc tacgttttgg agttggtcaa tttcttcatc gctgatttcg atactaaatt
      181 catcttccag agtcaagata aactccatca agtcaacaga atccgcatcc aaatcgtctt
      241 tcagactcaa ggattctgtc acgacaaagt cctctccctg tcgctcttgg ataatggtca
      301 caatacggtc aaaaatttct ttttttgtca tctcttttat tctcctgaaa attcacgcgc
      361 agtctgggca accacgtctg tttctagcat ggtacggatc tgacgaatcg tactataaac
      421 agccttggca tcgcttgagc catgagtctt gacaacaggt gccttaacac caaacaagac
      481 cgctccacca acatctgaat aattgagctg ttttttcaaa ccactgaggc tgtccttgag
      541 aaggagggca cctagtttcg ctcgaagacc accacctgta atagctgtct tgagcaagcc
      601 catgattccc atagctgtcc cttcgatgga tttgagcaca gcgtttcccg tgaaaccatc
      661 tgccacaaca acatctgcaa cgccattcat caaatcacgc gcttccacgt ttccgataaa
      721 gttcaaactt tcatcagccg ccagtaattc ataagtttcc ttacgaagcg ggtcgccctt
      781 gctactctct gttccgttgt tgagcaaacc aacgcgtggt tgcgcaatgc cacggacatt
      841 tttagaatag aaggaaccta gaaccgcata ttgatggagg tgctgggctg tattttctgc
      901 attggcacca aggtctagca tgtcaaaacc ttttccatca acggtaggca aggtagacat
      961 gagtccagga cggtcgatat tcttgatacg acccacgatg aagaatcctg ctgccaacaa
     1021 ggcacctgta ttcccagccg aaaggacagc gtctgcttca ccatctttga cagccttggc
     1081 tgccaatacc atactggcat ttttcttatt cctaatagct ctcgtaggtt catcatccga
     1141 atcaatcttc tcatccgtat ggataatgct gacgcgctct gtcgctgtca gatattgctt
     1201 gattttagct tcatctccgt aaagttgaac ctcgatatct gaaaagtcag atagggcttg
     1261 attgacaccc tcaacaatgg cctgaggtgc gtaatcgccc cccatggcat ctactgcgat
     1321 ttttttcatt tcttttcctc ttttagtaat tgtccccagt ctgctaggga atcaataaat
     1381 ttctttgatt ttaggtgaat cccaacgtac tcttcatata attgatccat aaattggcgt
     1441 agctcttgct tgattccagg cttgagcgaa atggtctcca aagtctcaaa atcaatagct
     1501 tgaaattgat tgagcagata ggggatattg ggattgagat gacaacgtct cttatcctca
     1561 tgataatgct ctggacagag gcaggctcca tatttgaaag aaaagtcaaa agcctgacca
     1621 acccgatggc agaagacaca ctcattaaaa ttgaggctga ttccaaatcg agtcaaaatt
     1681 tgaatttcaa aaatattggt caaaacctga taatccaagc ctgcttccat caactccaaa
     1741 gtcttttgca aaaaagcaaa caagggagca tcctgctgat tgtcctgcaa actagcatct
     1801 gcaagagctg ccacataggt cgcataggcc atgacaaaga ggtcactatt aatcttggga
     1861 aaagtcatga cctcatgata gtcttcgatg taactgagtc cgtcatcatt gattcgcaag
     1921 agaaatcgtg ccagcaccaa gggctgaata acaggcgcca gcttagactg accagcgtgt
     1981 ttgacaaaaa acatgcgttt gccaacctgc tctgtaaaaa ttttgacgag cttgtcatcc
     2041 tcacgaaaat tgcgattgta aagcaccaag ccttgactcg tgatagactg aatcatgctt
     2101 ctctcatgta ctcctcaagt cgtttcatgg cttctttgat agtctccatg ctggctgcat
     2161 aagataggcg gacgtagcct tccccgtaac gtccaaaggc tgcaccaggg ataaaggcaa
     2221 cggccttctt ctgagcaaaa tccttcagaa aagcaaagga gtcttgattg tagcccgctg
     2281 gaattttagc aaaaatatag aaggcaccgt ctggtttgat aatctcaaaa ccaagagcag
     2341 tcattttttc gatgatatag tcccgacgct ggatatattc cttcttcatg ggctccgcat
     2401 catttttacc agccgtcaag gcttctaccg cagcatgttg cgccatggta tttgcggcag
     2461 tgaccaagta ttggtgactc ttgattaact gggctgtgaa ggccgcagga gcgaaaatca
     2521 gccccaaacg ccaacctgtc atggcatgcg atttagacaa accattgata ataatagcct
     2581 ggtctctcaa catcgttcct agagacacat gggcttcgcc tgtgtaggtc aattctgagt
     2641 aaacctcatc acagacaaca aaaatttcgt acttgcgtaa aacagctgcc aaggcctcta
     2701 actgctctcg actgtaggta attcctgtcg gattggctgg atagttgaga ataaccgcct
     2761 tgagcttatc accctgctcc aaaatggcct tctccaacat ctcaggagtc aagacaaaac
     2821 cattttcagt cgtatcaatc tcaacaattt ctgccccaac taagttaaca atcggttcat
     2881 agcctggata agcaggagct ggcaaaagta ccttgtctcc ctcttccaaa atagccgtca
     2941 aagtcgcaga taaagcctct gtcgccccaa ttgtaaccaa gatttcattt tcaggagcat
     3001 agtccagttg gtacttttcc ttaacaaagt cactggctgc ctgacgtaga gtcagcagac
     3061 cactcatccc tgtatagtag gattggttct gatcaatcgc tcgcttggcc gcctccttga
     3121 catggtctgg cgttgtaaaa tcaggttccc ccaaggtcaa acgcaagacc ccaggaatct
     3181 ccgaaataac ctggtcaaac tgacgaatca acgaaacttg aattttatct aactgtttat
     3241 taaagcgctt agttaagtcc atagatacct cctactttca aaacgtatct ctattatact
     3301 acaaaagccc cccgaccgca aaaatacatt agagaatagc tttccacttt ctattttact
     3361 tttcctgttt acaggtctat aatggtaaca gattctattt ggaggttttt atgtcatttc
     3421 tatcaaaaaa tggagcaggc atcttggtct gccttctcat ttctatcgta tcttggtact
     3481 taggaggatt cttccctgtg attggcgcgc ccgtttttgc gatttttatg ggcatgctcc
     3541 tacatccctt tctctcgtct tataaacaac tggatgttgg attgaccttt agttccaaga
     3601 aattgctcca gtatgccgtt atcttgcttg gttttggtct caatatctct caagtcttcg
     3661 cagttgggca atcttcactc cctgtcatcc tttccaccat ttcaatagcc ttgattgttg
     3721 cctacctctt ccagcgcttc tttgccctgg atacaaaact ggctaccttg attggagtag
     3781 gttcttctat ctgtgggggt tctgccattg cagcgacagc gcctgttatc catgctaagg
     3841 aaaaggaagt agcccaagcc atctccgtta tctttttctt caatgtcttg gctgcgctca
     3901 tctttccaac cctcggcacc tggcttcatc tatccaatga cggcttcgcc ctctttgcag
     3961 gaactgcggt caatgatact tcctctgtaa ccgccacagc tagcgcttgg gacagtctct
     4021 accagaccaa taccctcgaa tccgcaacca ttgtcaaact cacgcgcacc ctagctatca
     4081 tccccatcac tctctttctc tcctactggc aaagtcgcga gcaaaaaaat aagcaaggct
     4141 tacaactgaa aaaagtcttc ccacttttta tccttcactt catccttgca tcgctcctaa
     4201 ccacccttct gacctctctc ggtgtgtcta gtagtttctt tacccctctc aaacaactct
     4261 ctaaattcct cattatcatg gccatgagtg ccatcggtct caaaactaat ctggtcgcta
     4321 tggtcaaatc cagtggaaaa tccattgttc tcggagccgt ctgctggatt gccatcatcc
     4381 tcaccagcct tggtatgcag acccttatcg gcattttcta atactcttcg aaaatctctt
     4441 caaaccacgt caacgtcgcc ttgccgtata tatgttactg acttcgtcag ttctatctgc
     4501 aacctcaaaa cggtgttttg agctgacttc gtcagttcta tctacaacct caaaacagtg
     4561 ttttgagcag cccgcggcta gtttcctagt ttgctctttg attttcattg agtataacac
     4621 aaaaggtagc ccatcagcta cctttttctt atgcttcctc aatcaagcga gtatgttctc
     4681 tcttgataca gcgattcatc acgatatcat cacatccacc atcacgcaaa atctctttcg
     4741 cttctaaact ttcaagtcct agctgtgccc aaaaaatctt ggcatcagct ttgagaaaat
     4801 cacgcgccac atcgggcaga aattcactgc gacgataaac attgacaata tctacaggaa
     4861 aaggaatttc agcgaggcta gcataagcct tttcacccaa gatttcgcca cctgccgcct
     4921 tgggattgac tgggatgatt ttatagcccc gagcctgcat ttcctttgtt actcgattgc
     4981 tggttgtttc ttcacggtca gacaaaccca ccacagcaag ggttttactc gttgcgagat
     5041 actgacgaat cacgccatca cttggattga taaattcttg actcatagaa atcctccttt
     5101 ttcatcagta tagcacattt tgaaaaggtt tgcagaattc tactacaaaa aaggaggact
     5161 agcccccttt ttatttagcc tcgtaccagg ttgccccttc attctcatct gcgataagag
     5221 gaacactgag ttgaatggct tcttccatgg tttgtttcac caattttttc atctctacca
     5281 attcagattt aggcacttca aggacgattt catcgtgcac ttgtaacagc atcttagtct
     5341 gataaccacc tgcaaccaag gctttatcca gctgaatcat ggcaatcttg agaatatctg
     5401 ctgccgaacc ctggataggt gagttgatag cagttcgctc cgcaaaacca cgaatattga
     5461 agttgcgcga attgatatct ggcaactcac ggcgacgctt aaagagggtc tctacatagc
     5521 ccttatcacg cgcctcccgc accacttcat ccatgtagtt tttaatacct ggaaaacgtt
     5581 caaagtaggt atcaatgtag gctttggctt ccttacgact aattcccaaa ttattagaca
     5641 agccaaagtc tgaaatccca taaaccactc caaagttaac tgccttggca ttgcgacggt
     5701 catttgcagt cacattatca ggacgctcaa tgccaaagac ccgcatggct gtcgaagtat
     5761 ggatatctgc cccctcttgg aaggccttaa tcaagtgctc atccttagaa atatgcgcca
     5821 aaacgcgcaa ttcaatctgt gaatagtcag agctgagtag cacactatcc tcccactctg
     5881 gcacaaaagc cttccgaatc aagcgccctt gttccaatcg ggcaggaata ttttgcaagt
     5941 ttggatccac actagacaaa cgcccggtct gggtcaaatc ctgcaaatag cgagtatgaa
     6001 tctttccatc agccaaaatc cagtcctgca agccaattac ataagtagat tgaatcttag
     6061 caatttgacg gtaatccagg attttcttaa caatcggagc aataggagcg agacgctcca
     6121 aaacatccac tgctgtcgaa taacctgtct tggttttctt agtgtattct agaggaagtc
     6181 ccaatttctc aaagagaagc acgcccaact gcttaggcga gttgacatta aactcctcac
     6241 cagccagctc gtaaatctct tgagtcagtt tttcaatgac aagctcattt tcagcctgca
     6301 tctcaagcaa ggtctctttc ttgaccacaa tcccagcaat ttccatcttg gcaaggacaa
     6361 aagccagagg ttgctccata tcataaagaa gctctaattg cccattttcg ctgagttttt
     6421 caagtaaaat aggctctgtt tctaccaaaa cagcaagttt acaagctaag tgttccaaga
     6481 atttctcacg ttcaggaatg gcctttttaa cacccttacc gtagaaagtt tcatcatcaa
     6541 ccaagtaagg ctgaccataa agactagcga tggtcgcaat ttcattgtcc tccacagtcg
     6601 aaaggaggta tttagccaaa cggatgtcaa aagcaggcgc ctgcaaatcc acaccaaaac
     6661 gttgcaaaag aactttaacc ttcttaaagt cataaactct cagagatgtt ttttctaaga
     6721 aatccttgaa aatcgggtct tgcaacagct caagcttgtc tgtggcatag agcttatcct
     6781 cacaagacca ggcaaatcca accaaattat ccgtatggta attctcacca aaaagctcaa
     6841 agtggaagat agactcttca ctcagcatat cttgactgat ttggtcaaca atagtaaaat
     6901 ccaaaccctt agccacatca gctgacgaca catttaaagc ctgcttgagc tgtttgaatc
     6961 ccatctcatc gtaaaatttc ccaagatttt caacatctgg accactatag accaagtcct
     7021 ctaaaccaat cgcaatcggt gccttggtat caatggtcgc tagtgtttta gacaaaaagg
     7081 cctgttcctt gtcattgatg agattttcct tcatcttaga agtcttcatt ccatcaatat
     7141 tttcataaat cccctcaagc gaaccatgct ccagcaagag cttaataccc gtcttttcac
     7201 cgactttggt caccccaggg atattatccg acttatcacc catgagcgcc ttgagatcga
     7261 taaactgagc tggtgtgagg cccatttctt ccatgaggta atctggcgta aaggcctcaa
     7321 actcagccac acctttcttg gaaatttcaa ccaccgtatg ctcatccgtc agctgaatca
     7381 aatccttgtc cccactgaca atggtaatat caaaaccatc ctgctctgct agcttatcca
     7441 gcgtcccaat gatgtcatcc gcctcatact gagccagctc atagtgacga atccccatat
     7501 gatccagcaa ctcacgaatg aaaggaaatt gctcacgaaa ctcatcagga gtcttggccc
     7561 gaccaccctt atagtccgca tacatctctg tccggaaggt cgtctttccc gcatcaaaag
     7621 ccaccaaaat atgactcggc tcaacccgct ccaacaaatg actcaacatc aactgaaaac
     7681 cataaatcgc attggtatgc aaaccagccg cattcttaaa acggtccaac tgctgataca
     7741 gcgcaaaaaa cgcccgaaaa gctacagaag acccatcaat caataataat tttttcttat
     7801 ccatacaccc attataaagg aaagaatcaa aaaataccat tgggaagagc tagagcaagt
     7861 atttttcaaa ctttttccga ataaatagat agagccaaag aatttagtaa acctagattt
     7921 aaaaatgtgc tataatatag tatattgaat ctataatagt acaccttgac tgctaaaata
     7981 tttctataaa ttaatttgac tttcctgata gagttattca catcttattt caactcacta
     8041 tagaaggagg aataggagga ttctcagaca tccgggcatc agcccaacta atgatttgat
     8101 tgctaagaaa atattcagca atccagaaat cacttgtcaa tttattcgcg atatgctgga
     8161 cttgccagca aaaaatgtga ccattttgga gggaagcgat attcacgtat tactctccat
     8221 gccttactcg gtgcaggatt tttataccag tatagacgtc ttggcggagt tggataacgg
     8281 tactcaagta attattgaga ttcaagtcca tcatcagaat tttttcatca atcacttgtg
     8341 ggcttacctg tgcagtcagg ttaatcaaaa tcttgaaaaa attcgtcagc gagaaggtga
     8401 tactcactag agctacaaac acatcgctcc tgtttacgcc attgctatcg tggatagtaa
     8461 ttatttctca gatgacctgg cttttcatag ctttagtatg cgcgaagaca caacaggtga
     8521 ggtattggcg attaccaaca atggacagga aaaccatctg gttaagatgg cattcttgga
     8581 attaaaaaat acagagaaac cagcaaagac aaggttcgca agccatggtt ggagtttttc
     8641 ggcaacaagc cctttaccca gcaacctgag cgagccatta cccaagcaaa tcaactgctg
     8701 gactacaaga gctggtccga ggaggacagg aaaatgttta gtcaactata tatgcgagaa
     8761 gaacaagtct tgttagcaca ggactatgcc ttggaaactg ctagggctga aggccttgaa
     8821 caaggactag agcgtgggaa agttgaagga agggcagaaa ggaaactttt tgccttccta
     8881 gacacagtac gccaaggtct tctgacttct gaggttgcca gccagcaatt aggtatgtca
     8941 gtatctgaat ttgaggcact gttgtaaaat ggctccataa tatccatagt gggtaaatcc
     9001 cctatggata ttatggagcc tattttgtgt agaaaaaaag tcccatatga cctataatga
     9061 aaagcgacca aacaactcat tagaaagatt catatggaac aattacattt tatcacaaaa
     9121 ttactagaca ttaaagaccc taatgtccag attttagaca tcatcaataa ggatacacac
     9181 aaggaaatca tcgccaaact ggactacgac gctccatctt gccctgagtg cggaaaccaa
     9241 ttgaagaaat atgattttca aaaaccttct aaaattcctt atcttgaaac gactggtata
     9301 cctactagaa ttctccttag aaagcgtcga ttcaagtgct atcactgttc aaaaatgatg
     9361 gtcgctgaaa cttctgatga cgtacagtca tatttcttct ctttttatta tatcacagtt
     9421 ttaaatctag ctttactaga ttcaccgcta ctatctattt attcggaaaa aagacgaaaa
     9481 aacctgagaa tcatctcagg cttggtcatt aaattttttt ctcaatatcg aaaagtggag
     9541 aaagtggtcg tttttcatga atacgtacga tagcatcccc taggagatga gcgattgaaa
     9601 tctgctcaat cttatcaatc aaacgctctt ctggcagata gatggtatcc aaaacaacca
     9661 atttcttaat agctgatttt tggatattgt ccgtagcagg accagaaaga actgggtgcg
     9721 tacagcttgc atagacttca acagcaccag cttccgcaag agcatctgcc gcatgacaaa
     9781 tcgttccagc ggtatcaatc atatcatcaa tcaagataca agtcttgcct tcaaccttac
     9841 cgatgatgtt cataacttca ctagtattca tcttatcaac gctacgacgt ttatcaataa
     9901 tagcgataga tgttttcaaa aattctgcca acttacgagc acgagtcacc cctccatggt
     9961 ccgggctgac aaccacatag tcagaaccaa ccataccacg ccgctcaaaa taatctgcaa
    10021 ttagaggagc acccatcaaa tgatccacag gaatatcaaa gaatccttga atttgcgcag
    10081 catgcaagtc gatggtcaat aaacgatcca ctccagctac ttcaagcata tttgcgacaa
    10141 gttttgaagt gattggctca cgcgctctcg cctttctatc ctgacgtgca tacccatagt
    10201 aaggcatgac aacattgaca gactctgcac tcgcacgctt caaagcatct accataatca
    10261 aaatttcaag cagattgtca tttacaggcg aactagttga ttgtaagata aagacgtgtt
    10321 tcccacggat tgattcttca atgttgacct gaatctctcc atctgaaaat tggcgaacac
    10381 ttgatttccc caactctatc ccaatctcct gcgccacacg ttctgccaat tctttattag
    10441 aagaaagggc aaacagcttt aaatcagaaa aagacatgat ttcctccggt atatatgtat
    10501 aacttgtgct tttcacaaga ttttccatct accattgtag cgctttttgc actatttttc
    10561 aatcaaaaat aaaagaaggg caccatattt gtacccttgc atcattcttt tgaaaaatat
    10621 tctaggtcat caactcattg tgtttctcaa caaagcaata agcatgataa aaaccataga
    10681 gagcaatagc cgtaaccact ggaatcgcta aaggcaactc tgtttccaac tccacaaaag
    10741 gagagttaaa caagaagtga gttcccaagg ctaaacctag aaaaataagg ccctgtttct
    10801 tgccaacctt ctgtccttta taggctctgt aaagcaagta aacacctact acagctagac
    10861 ctgaaaaagt ccagtgagag gcaattcctg agatgatacg ctctaaaatt cgcgaaatag
    10921 taaagtcaaa gccctctggc aaatccgtac gaatataacc aatatcctta atcatttgga
    10981 atcccaaacc ggaagcaatt ccaagtaaaa acaaagattt taattttcgc acaggaatca
    11041 aagccaaaac aaaaacaagt ggcaataatt tcaagggttc ttctaccaaa ggagccacaa
    11101 tagcactttc aaaggcattt aaaaatgtac tatctgggaa aagaaccccc agtaaatcat
    11161 ggatataagt attagcaaaa ctagacaacc agcctgaaag gaacatccct cccaataaag
    11221 acagaatcaa aaccttcttt ggcaattccc atttttccca atacggaaga gaaaataaag
    11281 agccggaatc atgtaaaaga gagctagaaa gatagaaact cccattagtc catattccgc
    11341 acctgacctc gaaccgtccg tatagtagat ggtttcatac tgtaaaccaa tacatagcaa
    11401 taaaataaaa ataaataaaa tactgctttt cttcatacac tttctttcta aatgaagtat
    11461 ttataattct acgactgtca tacttcctgt atcaacattg taaatggcac cagagataat
    11521 gacatcgtct ggtattaggg gagactcgat aagcagttgc atatcctcgc gtacactctc
    11581 ttctatatct tggaagggca agaagtcctg gtctgacaca tctacaccta attcctcttt
    11641 taaatactcc tgaaaaggtt cattttcaaa ggtctgagca ccacagtctg tatggtgcaa
    11701 taccacaatc tctcttgtcc ccatttgttg ctgggaaata actagcgaac gaatcatgtc
    11761 ttcagtcact cgaccacctg cattccgcaa gatatgagca tccccaagtg ccaagcccag
    11821 agcttgcgca acgtgcagac gagagtccat acaggtcaca atagctactc ttgttttggg
    11881 tttaagtggc agatttaact gcccatgtag ggcaacataa gcctgattag cttgcataaa
    11941 ctgttcaaaa tacgacacga ttccctcctt gaaaatttga tagtcaaata tttctcctat
    12001 cttatcattt ttaagagaat ttgtcacgga ttatgcaaag acctttttca aaacttcctg
    12061 aatcgttgtc acgccaatga cctgaatttc cttaggcaga gtgattcctg tcaaggaatt
    12121 cttaggtaca taaatcttag taaagcccag tttagcagct tcgttgatgc gttgctcaat
    12181 acgattcacg cgccgaatct ctcctgtcaa gcccagttct ccgacaaaac attcctgagg
    12241 attagttggc ttgtctttgt agctcgaagc aatagcaact gcaacagcca agtcaatcgc
    12301 aggttcatcc aatttaacac caccagcaga tttgagatag gcatcctgat tttgcaagag
    12361 aagccctgcc cgtttttcca aaacagccat aatcaagcta gcacggttaa aatcaagtcc
    12421 tgtcgtagta cgcttggcat ttccaaacat ggtcggtgtt accaaagcct gaacctccgc
    12481 caaaatcgga cgcgtccctt ccatggttac aacgatggag gaaccagtcg ccccatccaa
    12541 acgctcttct aggaaaactt gactcggatt gagtacctca accaagccgc ccgactgcat
    12601 ctcaaaaatc ccaatctcat tagtggaacc aaaacgattt ttgaccgctc tcaagatacg
    12661 aaaggtatgg tggcgctccc cttcaaagta aagcaccgta tccaccatat gctccaacat
    12721 acgaggtcca gccaaggtac cctccttggt cacatgacct acgataaaga tggcgatatt
    12781 atttgtctta gccaactgca tgagctcagc cgtcacctca cgcacctgag aaacagaccc
    12841 ctgcacccct gaaatctcag gagacataat ggtctgaatg gagtcaataa taaggaaatc
    12901 tggttggatg cgctctactt ctgcacgaac actctgcata ttggtctctg catagaggta
    12961 aaactcgcta tcaatatcac ccaagcgctc tgcacggagt ttaatctgct gggcagactc
    13021 ttcaccactg acataaagaa ccgttccaac ttgagacagc tgggtagaga cttgtaggag
    13081 aagggttgat tttccaatcc caggatcccc accgatgagg acgagacttc ctggtaccac
    13141 tccgcctcca agtacacggt tgaattcctc catctccgtc ttggttcgat tgacattgat
    13201 tgaagtcacc tcagccagtt tcatgggctt ggttttctca cctgtcaagg acacacgcgc
    13261 attcttgacc tcggcaacct caatctcttc tacaaaagaa gaccaagacc cacagttggg
    13321 gcatcgtccc agatatttag gggaattata cccacaattt tgacatacaa atgtcgcttt
    13381 tttctttgcg atgataaacc tctttctata tctctaactc acactcaatc acttggcaaa
    13441 aatcaatctt ctcatttggc acaaactggc gcatgagcat tcgatgagca acaactacca
    13501 cagtctgatg ttctcgatac ttagacatac attctagaaa ccgagacttc atttccgtag
    13561 ctgtctcata ttgaatagga ctattaggaa gtaactcccc cctgttttct aaaaacagtc
    13621 ttctagctgt ttcaaagttt tctattcctg ttttatagac ctgccattca tgtaataaag
    13681 gctctactct taaaggaaga cccgtagcac agaccacata cgaagccgtt tctaaagctc
    13741 ttgcgactgc agaagatacg attatttcag ctgacgagag taaaggattt ttgctcaatt
    13801 tctggacttg ctgccgtccc atatcagaca agggtgccaa atctatccca aatcctatat
    13861 aagaacgctc ctctaactca cggtaatctg gctccccatg acgtacaaag ataatcttca
    13921 ttctagtgcc ctgtcgatcc aaatccacca gttcgaacgc catcagccgc atctccatct
    13981 gcaattaaga aagtagcaaa aacagcctgg acaatacgtt ccccaacttc aagaacaacc
    14041 tcttggtctg tgatattctt catctgcgca aaaatatgcc cttcatttcc aggatttcca
    14101 taataatccc catcaatgac cccaactgag ttaattaaaa ccaagccctt cttacgagga
    14161 tttgaagaac gatcatagag gtagagaacc tcagtcggct gcatataagc cttaacccct
    14221 gtcggaacca agacaatctc tcctggcgca acaactgtac gcacagcaac ctttaagtcg
    14281 taaccagccg catgcgctgt ctcacgcttg ggcaataaat tttcatctgt aaaactcgaa
    14341 accaattcaa aaccacgaat tttcataatt ttctcttttc tattatcatt tattctagat
    14401 tattctatct tatttattcg gaaaaagcac gaaaaaaaga gcacacaaca attataggcg
    14461 atacgataat ttacactgtt tcacaatacg ttgaaattta gagctttaaa gcgagggcaa
    14521 agttgatttt ttacatcgtt ttacagaggt ttacgacact tttgcccctt ttttgcccct
    14581 tttgagcaaa caaaaaaacc gcaagcctga gcctgcggtg aaagaacaat ttagaaagtt
    14641 tcctttctat ttatttaact gtaatcaagc catctggctc tactgtgaac tctggcttat
    14701 ctgccagtgt tccgtctggt ttgaggtagt accagcctgt tccgtccgct gactggataa
    14761 aagcatttga taccatagca ccttctttag cgtctaagta gtaccaagtg tccttgtact
    14821 tgacccaacc tatttgcata gcaccttcta catcaaaata gtaccacttg tcagcgattt
    14881 tcttccagcc tgtggccatt tcgcctgatt ggtcaaagta ataccaatta ccgtctgtgt
    14941 gcttcttcca gcggtctgca agcatatagc ctgagccatc gaaataatac caggtaccgt
    15001 tgattttctc aaacttatag aaaggaggag atagtatggc aaatactcca ataaaacctg
    15061 gaacagataa tcagaaacct ggtcgctatg tagaggtagg acctcgtggc ggaaaagtta
    15121 ctaatggtca taccgcaact atcggaaaag gtgatcggct ccctccgaca tctgctaaag
    15181 gcaacggttg gaaaaaagtc taatcttcgt ttgcgtacaa tcgttcaatg gttgtacgct
    15241 ttttccatac acaaaagcac attcccaaaa aatcaatttg aatccatgct tcggcgtaat
    15301 ctttcccatt gctggcatag tgagttatat aatggtgaat cattttattc cttcctccta
    15361 ttgagttact tgagaagtat catgaatggc ttcatagcta agacgcttaa attcttctga
    15421 gtctatctga aaattgatag gctttttttg taaacactca agaaaactag tgtttcttaa
    15481 aagtttttca actaactcag ggtctgcctt tacaaaggtg gactcttttt gtccactata
    15541 cggatatcgt tttggtctca ttttcctact cctcaaatct ttcctactca atcccataat
    15601 cttcaataac ctgaagaatg aaactgttcg ctcgtggacc tttagtcgtt ccacttagaa
    15661 tgtttgtcac ttcctgtcgt ttaaagccgt aagcaaccgc tagagttgct tttttaatgc
    15721 ctttctcttt caagaaagca ataactcttt cgcgaccgtt tgcgatatct ggcatatttt
    15781 ctcctttctt tttctttctt ctttttctgc tataatataa gcagaaagga gttaacctta
    15841 tgacttttaa agaatattta ctcaaagcaa gcaaacgcga catctacgat gatggtaaag
    15901 attttgattt tgaaaccatc tttgctagag aaatattacg ttatgcacac gattctgaac
    15961 tggaaaccaa aacaggtttc tttcgtcatc ttgaaatcat gaatgctgat tcgtggtttg
    16021 ttgaacttgc tcgctcaatt tatcaagatt ttgagaaatc aatttcagat tctcactaat
    16081 cgagcgtgac ttttttgata tggcaatctc agaaatttac caccagcgct gactacctta
    16141 atgacttttt caaggtggtc tttttcttgt tctaaatttt taagaatact taccatcagc
    16201 acgttcctcc tctttactta tttgtaaata agaaacaact aaaaatgtaa ctatttttct
    16261 gcattatact tgacaactta caccaaatcg gctaaaatta aagcataata aaaacaccaa
    16321 taaatctata aataccgttc gccaaaacat ttttataatt tatttcttag ttgttttttt
    16381 agttgtttat cacttacaaa aaacatttta caccttttgg gataattagt caaccttttt
    16441 acaccaaatt tgttaaattt ttttgtgatg tcttagaaag gttgatttaa caatgtttga
    16501 gacatttgaa aaaataaaag aattggcaaa aaagcgtgga aaagctcttg gacaagtaga
    16561 agaagactta ggttatggta gaaatacact ctataagata aaaaattcta cgccaaacgc
    16621 tgaacgtatc gcagaaattg ctaattattt caacgtatcc accgactacc tgctcggacg
    16681 aacagataac cctgctatcg ctgggagtga tgaatttgcc caagtaaacg gacaaatcat
    16741 agacttacgc aaagcagcag ccaacaccat gttatttgac gggaaaccac taaatgaaga
    16801 tgatatcgac ttcattacat ccgtcctatc cgcccacttc aaaagcaaag gagaacgcta
    16861 atgactatca ctatcaactt cacagaaaaa aattcctaca ttacggacta cctaaacaaa
    16921 cacggtatcg acacaacgac catggatttt gacgacttca tggcactcat ggaagatatc
    16981 gaagacgcac gagcagccga ccaagcctat atggagtatt tagccgaccc agctacttat
    17041 accatggatg aggtcttgga tgaactagga ctaactcgag aggatattgc ttaatgtatc
    17101 ggctagatat tgataaaaaa gctctcaagc aacttaaaaa actagatacc ccaaccagaa
    17161 aacaaatcct atcctggctt gctaaaaaca ttgaaaacac gaccaatcca cgacaacacg
    17221 gaaaagcact aaaagccaac cttgcaggtt actggcgata cagagtagag aattaccgca
    17281 tcatctgtga tatccaagac gataaactag tcgtcctagc cgtggaaatc gcccaccgca
    17341 gagatgtcta taaataacga aggagaacta tgacactcgc taaactctgc gaagaatatc
    17401 aagtagaact ttgtctcttc gacggttcaa actggcacaa tagcggtttc tacaatccag
    17461 acacaaacgt gctcgctatt gaccacaact tgactcctga acaacaaatc caagtcgccc
    17521 tacacgaact tggacacaaa gaccacacac gctcagagca ccagaacgcc cgtctacgct
    17581 gtgaaaacga agctgatagg aatatgatcc atcatctcgt aaaagacgct ctagaaaact
    17641 tagacgaccc cacagagttt gattacctca aattcatgtc ttactacaat ctaaaaacca
    17701 tgacaaatga aatcatggtt aaagaagagt atttagcatt agtaaattaa aaaaaggagt
    17761 atcaatatgg aaattgataa agtaaaagcc gatttaaaac aagtcggcaa acgtgtagca
    17821 gacctcagcc aaagcattac gaatgaagaa caaacaaaga atgccttcat tatgccgttc
    17881 ttccaagcgc ttggatatga tatcttcaat ccacttgaat ttgtcccgga atttactgcc
    17941 gacgtgggca ttaaaaaagg cgaaaaagtc gactatgcga tcattttgga tggcgagcct
    18001 caaatcctaa ttgaatgtaa atcaattaca gaaaacctta ctaagcacga ctctcaacta
    18061 ttcagatatt tcgtaactac taaatcaaaa ttcggtatct tgacaaatgg tagagaatat
    18121 aaattcttta ctgatttaga tgagccaaat aaaatggaca caactccatt cttaacaatc
    18181 gatgtgactg atatcaaaga aaatcaattt actgaaatca tcaaattcca caaagagaat
    18241 tttgatattg ataatattgt ttcatcagct tctgaattga aatacctcaa caatcttaaa
    18301 gcgttcctta ctgaaaatat cactacaccg tcagatagct tcctcagata tctaacttct
    18361 gaaatctatg aagggcgtgt tactcaaaat atcttaacga cattttctcc cattattgtg
    18421 aaagggttta atcaattcat cacagagcga gttaatgaaa aattaagtgc tgcacttaat
    18481 acaagcgttg aaaccaaagt aacaaccgat attccaaaag ttgaagctga agctgaagag
    18541 attgtcgaag taactgacga aattatcaca actcctgctg aattagaagt ttatactgtt
    18601 gttaaaatgc ttgctaggga tgtagtttct ccagaacgtg tattttacag agataaccgt
    18661 agctatttca atgttttggt tgacgataac atcaaaaaat gggtattacg ttatcgttca
    18721 aattcaaaaa aaagcactat cgaaatccgt gataaaggca tcttcccggt gtctacccct
    18781 ctcgaagtcg caaattatgc caatgaaatt ttagaagtaa tcaagaaatt ctcataataa
    18841 aaaaagccct ctttactata cccattttat caaaaaagtg aggtaaaatc aatgtggatg
    18901 gaagaattgc caaacggcaa atataaattt tttgagagat acaaagatcc atatactgag
    18961 aaattaaaaa aagtctcagt aacgatggag aaaaaaactc cccaagcaag aaatcaagct
    19021 gcgattttac ttcaggaaaa gataaaacaa aagttaggag aaaaacaaca ttctgtttct
    19081 aatataactt ttgaaaaact atatgaagaa tttgaggaga attggaaaca cggcgtaaaa
    19141 aactcaaccg tctacgcttc aaagaatgta aaaaaagaga ttttaaagca gatagagggc
    19201 gactacctag ttagaaatat tgatagacgt ttattacaaa aagtaataga tcaactatta
    19261 caagatggga gatctcataa ctatgtttct aaaatcaaat tcaagctcaa tcagataatg
    19321 aaatttgcta tcagaatgaa ttatattgat acaaatgaaa tgctatttgt tgaaacgcct
    19381 agaaaagtaa ttacatccga cgaactcaaa aagaaaaata caaaatactt agaccaaaaa
    19441 gagtttaagt tattcatcca aaatttaaaa gacgaggccc tatgtgatta tcgaattaca
    19501 aagtatatcc gaatagctaa agttcttttt cttactggca tgaggtatgg agagctggca
    19561 gccttaaact acaaggaaga tatagatttt tctaaaaaga ctattcacat caagcataca
    19621 tacgatttca gacaaaaaga gagaactaca ccaaagacaa tcaagtccga tagggttata
    19681 acagcacctc aaaaagtgtt agatattatc aaagagcaaa taatagagaa tgcgacaaat
    19741 ggatttgata cagattttat tttcatcaat actctaggag aaccaataac aaatgccagg
    19801 gttatttgtg cattgaaaag acatggtcaa aaaatcggca tagaaaaaaa cataactaca
    19861 catacattta gacattctca catatcccta cttgctgagc tgggcattcc cttgactgcc
    19921 atcatggaca gagtagggca tagtgactca aagaccacac tagagattta ttctcacgtt
    19981 actcaaaaaa tggtatcaga catatctagc aagttagaca agataaaatt ttaaattgtg
    20041 cccctcgtct gccccttttt cttatacaag acaaacaaaa accccttaaa gtgttgattt
    20101 taaagggttt ttaaagtgca cgaaaaaaga gcacacaatt caaatcgctt agggctgctg
    20161 gattcctccc ctgacccgct tcacgcagaa ctgttgctcc actatttatt atatcacatt
    20221 cctattcatt ttaaaagcaa aattattttt tccgtctatt tctaaaaaaa tcctgcatga
    20281 tagctgcgca ttcatcttcc aaaattccta tttcaacctc cacacgatga ttgagacgct
    20341 catctgtcaa gatattgtac aaactcccag cagcgccaaa tttctggttt ttagccccat
    20401 agaccacatt tggaatgcgg gcaagcccaa tcgctccact acacatgaca caaggttcaa
    20461 tggtcacaaa aagtgtgcaa tccagcaagc gccagctctc ctcactcaag ttcgcatcct
    20521 ctatagccat aatttccgca tgcataaccg ctcgctgtaa ttcctcacgc gcattatgcc
    20581 cacgaccaat gatttcccca tctttgacaa tcacacaacc aattggaatt tcatcgtgtt
    20641 caagagcaat ctcagcctct ctcaaagcct ccctcataaa gacttctttt tcttcaagcg
    20701 tataatacat ctcttttctc ttttcctact tatcgatttt attattatat catgaatccc
    20761 aacacaaaaa aagccaccga atgcggtgac tctataggga gattattatg aaaaagaaaa
    20821 gtttaggata tttgttacaa caagttagga ggtcttcttg taaccgtcta tagtataccc
    20881 gacctatctt aaacaaatct taaaaatctc ttaggaccaa acactttcta aaatatttgt
    20941 ttgttcacga ccaggaccta ctgagaaagt agaaatacga acgccaacca attcactcac
    21001 acgacgaaca tagttacgcg cattctcagg aagatcttcc aaattgcgaa ctccggtaat
    21061 atcttctgac caacctggca actcttcata gataggcttg caacgtttca attgctcaag
    21121 actagctgga tagtagtcaa tacgttgacc gtcaagatca taggccacac agattttcac
    21181 agtatccaaa ccgctcaaaa catcaataga gttcaaagaa aggttagtaa taccagaaac
    21241 acgacggcta tgacgcatca caactgagtc aaaccaacct acacgacgtg gacgaccagt
    21301 tgttgtacca tattcatgac ccacttcacg gatacgttct cccacttcat caaacaactc
    21361 agttgggaaa ggaccatctc ctacacgact cgtataagct ttacatacac ctacaacctt
    21421 gtcaatcttg cttggaccga caccagaacc aattgtcaca ccaccagcta cagggtttga
    21481 tgacgtaaca aatggataag taccttggtc gatatctagc ataacacctt gtgcaccttc
    21541 aaaaagcaca cgtttgccat tatcaagcgc atcattcaag ataacagatg tatctatcac
    21601 gtatttcttg atttgttgac catattcgta atattcttca aaaatatcat cgaaaacaat
    21661 cgctttactg tcatacaatt tttcaaaaag acgattcttt tcagcaaggt tacgttctaa
    21721 acgctcacgg aaaatatctt tatctaaaag atctgcaata cgaattccaa cacgagcagc
    21781 cttgtccata taagctggac caattccctt aattgtcgta ccaatcttat tgtcgccctt
    21841 agcttcttct tgcaagcgat ccaactcgat atgataaggc aaaataacat gcgcacgatc
    21901 agaaatacgc aagttatcag ttgttacacc ttcctcatga agatagctca actcttttac
    21961 aagagattta ggatttacaa ccataccatt cccaatgaca gatatttttt cagggaagaa
    22021 aatcccagat ggaatcaagt gcaacttaaa tttcttaccg tcaatcacaa tcgtgtgacc
    22081 agcattatca ccaccttggt aacgtgcaat cacttctgca ttcgctgaaa ggaagtctgt
    22141 aatcttccct ttaccttcat caccccattg ggtacctaca acaacaactg aagtcataat
    22201 cttgtctgag ccctcaggct cttcctttct cacatacatg gcaggactct cacctgcaat
    22261 tatatcttac aatttattat aataaaaaat cgccttttta tcaagaagaa acaatagaaa
    22321 gatttgctat ttccaactat taaaaaatga tttagaaaaa ttactagcta tttactatca
    22381 tctttccata aaagagtaaa ttagttcgga aatttactaa aattacctca acaagaaata
    22441 aaaccccgat tcattaccaa tttttcaaga tacaaacgat aagcaacacg ataatggtaa
    22501 acgataaaat ccctacgaca accaatgcca tatctcacta aataataaat taaaaattta
    22561 aaatgaacat gttcccagtc aaaattatca ccaaatgtag gaccatactc ttcttcaata
    22621 ctatcataga aattagccat ctgctcataa attttttgta acataatcaa atactccttt
    22681 tcttttttat aaacttattc taacaaaaaa ttttacacat tcactatcaa ttcctgaatt
    22741 gttaaaatac cagcctcaac aagataaaaa taggaaaagt tgacaaaata gaaacaaatt
    22801 tgctacctaa atttcaaaca attaaagttc taaaaagacc gccttaaaac ttttgggtaa
    22861 atcctaggta ttatggttct gattttctag tataaaaaaa ttcaaactag aattcttctt
    22921 agaaaaggcc gttttaagtg ctatcattgc tcaaaaatgg agctcgctga gacttctatc
    22981 gtcaagaaga atcatcaaat tccttgtatc atcaaccaaa agattgctca gaagctaatt
    23041 gaaaagactt ctattaccga cattgatcat cagttgtcta tttcaacttc aactgtcatt
    23101 cgcaagatca ataattttca ctttgagcat gatttttcgc gtcttcctga gattatgtcc
    23161 taggacgttg aaacagtccg gggagtgact gtttcaatcg ggagatggag atgagcttta
    23221 ttgctcagga ctttgataaa ctcaatatca taactgttct tgagagcaga acacaagcca
    23281 tcatccgaaa tcccatgaat acaaggctat caagcgctac tggaagctca ttcaacaaga
    23341 tagtcagaaa ctgagtgata aacgatttta tcgccctact tttcgtatgc acttgactaa
    23401 taaagaaatt ctagataaac ttttgagcta ttccgaagac ttgaaacacc actataatct
    23461 ctatcagctc ttacttttcc acctcttttt cagactttgt ttaaaacctt cctcaaagat
    23521 aaagagaaaa tcgtcaacgc ccttcaatta ccttattcca acgccaaact ggaagccacc
    23581 aataatctca tcaaacttat caagtacaat gcctttggtt ttaggaactt tgaaaacttc
    23641 aaaaaagaaa ggacgaaatt tgtcctttct agatcttcgc tttcttcaac ccactacagt
    23701 tgacaaagaa ccgaaaaatg tctcgcctct aatatagtca attgaaacaa gaacaagaca
    23761 aaagagcttc ataaaaggta ttgcaacttg gtaatacctt tttgaggtgc tttttgatat
    23821 gagcccatgt tttctcaata gaattgtact caggtgagta gggaggaaga ggtaaaagtt
    23881 tatgcccaaa ctcttcacac aagagtgcta gcttacccat tctatggaat cttgcattgt
    23941 ccataatata gtagattgaa actagaatag tacacctcta cttctaaaac attgttagaa
    24001 ttcgatttta ctgttctaat cgatttgtcc tattcttatt tcattttact ataacacgaa
    24061 atagattatt attacataac aaaaaagagg tctaaacctc ttaactaaat tactccgcca
    24121 gtaggactcg aacctacgac atcatgatta acagtcatgc gctactacca actgagctat
    24181 ggcggatta
//
LOCUS       DBERPV010000031        24008 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.31, whole genome shotgun sequence.
ACCESSION   DBERPV010000031 DBERPV010000000
VERSION     DBERPV010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 24008)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24008
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.31"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..681
                     /locus_tag="ACL8C7_001557"
     CDS             <1..681
                     /locus_tag="ACL8C7_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HGS1395720.1"
                     /translation="APKPETPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNAN
                     GAMATGWAKVNGLWYYLNSNGAMATGWLQYNDSWYYLNTNGAMATGWLEYNGSWYYLN
                     ANGAMATGWLEYNGSWYYLNSNGAMATGWLQYNGSWYYLNANGAMATGWAKVNGSWYY
                     LNANGSMATGWVKDGDTWYYLEASGAMKANQWFKVSDKWYYVNGLGALAVNTTVDGYT
                     VNENGEWV"
     gene            1081..2202
                     /gene="mnmA"
                     /locus_tag="ACL8C7_001558"
     CDS             1081..2202
                     /gene="mnmA"
                     /locus_tag="ACL8C7_001558"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HGS1395721.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTTLLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVVRDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLKKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTRDMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            2343..2798
                     /locus_tag="ACL8C7_001559"
     CDS             2343..2798
                     /locus_tag="ACL8C7_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGS1395722.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALILQNRKLLVTKDKGKYYTIGGA
                     IQVNEKTEDAVVREVKEELGVKAQAGQLAFVVENRFEQDGFSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKFEDIQLVPAFLKTALPDWEGQLRHIHREE"
     gene            2808..4721
                     /gene="mnmG"
                     /locus_tag="ACL8C7_001560"
     CDS             2808..4721
                     /gene="mnmG"
                     /locus_tag="ACL8C7_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HGS1395723.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDKILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDAVPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEELDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(5055..6734)
                     /locus_tag="ACL8C7_001561"
     CDS             complement(5055..6734)
                     /locus_tag="ACL8C7_001561"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGS1395724.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6736..6969)
                     /locus_tag="ACL8C7_001562"
     CDS             complement(6736..6969)
                     /locus_tag="ACL8C7_001562"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002947111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase subunit epsilon"
                     /protein_id="HGS1395725.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDTSSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            7249..7464
                     /locus_tag="ACL8C7_001563"
                     /pseudo
     CDS             7249..7464
                     /locus_tag="ACL8C7_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282487.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7788..7940)
                     /gene="cibB"
                     /locus_tag="ACL8C7_001564"
     CDS             complement(7788..7940)
                     /gene="cibB"
                     /locus_tag="ACL8C7_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HGS1395726.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(7942..8127)
                     /gene="cibA"
                     /locus_tag="ACL8C7_001565"
     CDS             complement(7942..8127)
                     /gene="cibA"
                     /locus_tag="ACL8C7_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HGS1395727.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            8305..8988
                     /gene="tsaB"
                     /locus_tag="ACL8C7_001566"
     CDS             8305..8988
                     /gene="tsaB"
                     /locus_tag="ACL8C7_001566"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HGS1395728.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPH
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLSFEEVLEKVKGTSQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8985..9422
                     /gene="rimI"
                     /locus_tag="ACL8C7_001567"
     CDS             8985..9422
                     /gene="rimI"
                     /locus_tag="ACL8C7_001567"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HGS1395729.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVIAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            9412..10422
                     /gene="tsaD"
                     /locus_tag="ACL8C7_001568"
     CDS             9412..10422
                     /gene="tsaD"
                     /locus_tag="ACL8C7_001568"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HGS1395730.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLYHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(10462..11755)
                     /locus_tag="ACL8C7_001569"
                     /pseudo
     CDS             complement(10462..11755)
                     /locus_tag="ACL8C7_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(12091..12782)
                     /locus_tag="ACL8C7_001570"
                     /pseudo
     CDS             complement(12091..12782)
                     /locus_tag="ACL8C7_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839528.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            13025..14230
                     /locus_tag="ACL8C7_001571"
     CDS             13025..14230
                     /locus_tag="ACL8C7_001571"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGS1395731.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKQQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSNNFETALHVKNILK
                     LLKIQLIHCHGYSTNYFLYMLKKLDKNGFGKVKTVITCHGWVEYNLKKKFLTYFDFWT
                     YSMGDAFICVSETMKKRLESIIKNKKIVAINNGINVSNSDLDVVGVQDFKKEFCIPNN
                     KKIICYVGRLDPEKRPDRFLEFAEKLFLVREDVIFIMAGNGSMWAALKEKICHLKCRD
                     NFRLLGEIYPATIVYQISDLLYIPYDTEGIPMCVLESMSQGTPVLANNVGGLSEIIEH
                     RVDGFLFEKEDVEGVCACANFLLNDSEYLKYIGENSKSKIRKHFSVQKMFVETMRVYD
                     ELLEKSSHG"
     gene            14223..15098
                     /locus_tag="ACL8C7_001572"
     CDS             14223..15098
                     /locus_tag="ACL8C7_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGS1395732.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNLRNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDE
                     YMPDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIA
                     GTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENG
                     ITGVTQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCKALKV
                     IKKAREEKIFNEFLF"
     gene            15185..16801
                     /locus_tag="ACL8C7_001573"
     CDS             15185..16801
                     /locus_tag="ACL8C7_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS1395733.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLSGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            17061..17489
                     /locus_tag="ACL8C7_001574"
     CDS             17061..17489
                     /locus_tag="ACL8C7_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395734.1"
                     /translation="MSEIVEMSKKISDLNDKKEFHKKNCELRFQDSVLDNINSVPGTT
                     HLFSCLNIQILVKIILYIFRYNSCMKIFNFRDKELIFFNKIVNGLIQNIEENLEDDIE
                     RILKYLYICLFNEIFIIKNKVNFFDDVEFNQTLSEFLDKL"
     gene            17501..18250
                     /locus_tag="ACL8C7_001575"
     CDS             17501..18250
                     /locus_tag="ACL8C7_001575"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019213 - deacetylase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HGS1395735.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKIYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIIFWIKK"
     gene            18263..19435
                     /locus_tag="ACL8C7_001576"
     CDS             18263..19435
                     /locus_tag="ACL8C7_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HGS1395736.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GNETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     SFAERRSLNAEVVIKGVCLYPRIGNFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFTKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
     gene            19831..20694
                     /locus_tag="ACL8C7_001577"
     CDS             19831..20694
                     /locus_tag="ACL8C7_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HGS1395737.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACDGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMQIGRKVVDRFAHQDIAGLEQLLEEV
                     EQEQMAQTYRRLNAIVIKDAIHSLNKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNILSELMERKLFSYIPIFE
                     AELERMLRPYDVFEKVSWQFLKKMSVFLQTKGSNQKEIERFIQSLQVLENPQLIALFE
                     LRLQQYKKLID"
     gene            20980..21213
                     /locus_tag="ACL8C7_001578"
     CDS             20980..21213
                     /locus_tag="ACL8C7_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395738.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            21235..21912
                     /locus_tag="ACL8C7_001579"
     CDS             21235..21912
                     /locus_tag="ACL8C7_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGS1395739.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATNLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVKRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            21925..22590
                     /locus_tag="ACL8C7_001580"
     CDS             21925..22590
                     /locus_tag="ACL8C7_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGS1395740.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVTGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            22662..23888
                     /locus_tag="ACL8C7_001581"
     CDS             22662..23888
                     /locus_tag="ACL8C7_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGS1395741.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQILQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
BASE COUNT         7335 a         4063 c         5120 g         7490 t
ORIGIN      
        1 gctcctaaac cagaaactcc aaaaacaggc tggaaacaag aaaatggtat gtggtacttc
       61 tacaatacgg atggttcaat ggcaacaggc tggctacaaa ataatggctc atggtactac
      121 ctcaacgcta atggtgctat ggcaacaggt tgggctaaag tcaacggctt atggtattac
      181 ctcaacagca atggcgctat ggcgacagga tggctccaat acaatgattc atggtactac
      241 ctcaatacta atggtgctat ggcgacaggt tggctagaat acaatggttc atggtactac
      301 ctcaacgcta atggtgctat ggcgacaggt tggctagaat acaatggctc atggtactac
      361 ctcaacagca atggcgctat ggcgacaggt tggctccaat acaatggttc atggtactat
      421 ctaaacgcta acggcgctat ggcaacaggt tgggctaaag tcaacggttc atggtactac
      481 ctcaacgcta acggttcaat ggcaacaggt tgggtgaaag atggagatac ctggtactat
      541 cttgaagcat caggtgctat gaaagcaaac caatggttca aagtatcaga taaatggtac
      601 tatgtcaatg gcttaggtgc ccttgcagtc aacacaactg tagacggata tactgtcaat
      661 gaaaacggtg aatgggttta agccgattaa attaaatcat gttaagaaca tttgacattt
      721 taattttgaa acaaagataa ggttcgattg aatagattta tgttcgtatt ctttaggtac
      781 ctgtcttatg atttcaggaa atgtcattaa aaaaacgact ccttttctct aacttggaaa
      841 atagattaga gaaaatgggt tgttttattt attatagtta tttgaatgaa gataagaaga
      901 aggtatactc acatcattca caaatctgta tattgactat aagttttaaa aaacaatttt
      961 taagctcttc cttgtcttct ctaaccaagc gtgttataat gaatactgct caagcgacct
     1021 tcaatcgtga agcacacacg accttcaatc gtgaataaac gaatagatgg gagacttacc
     1081 atgagtgata actctaaaac acgtgttgtc gtggggatga gtggtggtgt tgattcgtcg
     1141 gtgacgactc ttcttctcaa ggagcagggc tacgatgtga tcggtatctt catgaagaac
     1201 tgggatgaca cagatgaaaa cggcgtctgt acggcgaccg aagattacaa ggatgtggtt
     1261 gcggtggcag accagattgg cattccctac tactctgtca attttgaaaa agagtactgg
     1321 gaccgcgttt ttgagtattt cctagcggaa taccgtgcgg gacgcacgcc aaatccggac
     1381 gttatgtgca acaaggaaat caagttcaag gcctttttgg actatgctat gaccttgggg
     1441 gcagactatg tagcgactgg gcattatgct cgagtggtgc gtgatgagga tggcactgtt
     1501 cacatgcttc gtggcgtgga caatggcaag gaccagacct atttcctcag ccaactttcg
     1561 caagaacaac ttcaaaaaac catgttccca ctaggacatt tgaaaaagcc tgaagttcga
     1621 aaactagcag aagaagcagg tctttcgact gctaagaaga aagactcgac agggatttgc
     1681 tttatcggag aaaagaactt taaaaacttc ctcagcaact acctgccagc tcagcctggt
     1741 cgcatgatga ctgtggatgg tcgcgatatg ggcgagcatg caggtcttat gtactatacg
     1801 attggtcagc gtggcgggct tggtatcggt ggacaacacg gtggtgacaa cgcgccgtgg
     1861 ttcgttgtcg gaaaagacct gagcaagaat attctctatg taggccaagg tttctaccat
     1921 gattcgctca tgtcaactag cctagaggct agccaagtcc actttactcg tgatatgccc
     1981 gaggagttta cgctagaatg tacggctaaa ttccgttacc gtcagcctga ctctaaggtg
     2041 accgtccatg tcaaaggaga caaggcagaa gttatctttg cggaaccaca acgcgcgatt
     2101 acaccaggac aggcagttgt cttttacgat ggcgaagagt gtctaggtgg cggtttgatt
     2161 gacaatgctt accgcgatgg acaagtttgt cagtacattt agattgacaa attttctcaa
     2221 tttgctacaa taataacagc aatagaaatg atggtcaaag ctcatggatg ttgcaggctt
     2281 ttttgtcctg cacttctttg gagttttgac tgtttttgtg tcgtttaagg gaaaggacaa
     2341 gaatgactca acaagacttt cggacaaaag tagacaatac ggtttttggt gttcgggcga
     2401 cagctttgat tcttcaaaat cgcaagcttc tagtcaccaa agacaagggc aagtattaca
     2461 ctatcggcgg tgcgattcaa gttaacgaaa aaacggaaga cgcggtagtc cgtgaagtga
     2521 aggaagaact gggtgtcaaa gctcaagctg ggcagctagc ttttgtggtt gaaaatcgtt
     2581 ttgaacagga cggtttttcc tatcacaata tcgaatttca ttatctggtg gacttgctgg
     2641 aggatgcccc attgaccatg caggaagatg agaaaaggca gccctgtgag tggattgact
     2701 tggataagtt tgaggatatc cagctagttc cagccttttt aaaaacggcc ctaccagatt
     2761 gggaaggcca actaagacac attcatcgtg aggaatagga gagaaacatg acttatcatt
     2821 ttactgaaga atacgatatt attgtaattg gtgcgggaca cgctggggtt gaggcttcct
     2881 tggccgctag ccgtatgggc tgtaaggttc tacttgcgac catcaatatt gaaatgctgg
     2941 ctttcatgcc ttgtaatccc tctatcggtg gttctgctaa ggggattgtc gtacgtgaag
     3001 tcgatgccct cggtggcgag atggccaaga ccattgacaa gacttacatc cagatgaaga
     3061 tgctcaacac agggaagggt cctgctgttc gtgcccttcg tgcgcaggct gacaaggaac
     3121 tttactctaa ggagatgcgc aagacagttg aaaatcaaga aaatctgacc cttcgtcaaa
     3181 ccatgattga taagattttg gtggaagatg gcaaggttgt cggtgttcgt acagcgactc
     3241 atcaagagta tgctgctaag gctgttattg tgacgacagg gactgctctc cgtggggaaa
     3301 ttatcatcgg agacctcaag tactcatcag gtcctaacca cagcttggct tctattaacc
     3361 tagctgacaa tctcaaggaa ctgggtctcg aaatcggtcg tttcaagaca ggaacccctc
     3421 cacgtgtcaa ggcctcttct atcaactacg acgtgacaga aatccaacca ggagacgcag
     3481 tacctaatca tttctcatac acttcacgtg atgaggatta tgtcaaagat caagtgccat
     3541 gctggttgac ctataccaat ggtaccagtc atgagattat tcaaaacaac ctccaccgtg
     3601 cgcctatgtt tacaggtgtg gtcaagggag tggggcctcg ttactgtccg tcgattgaag
     3661 acaagattgt gcgctttgcg gacaaggaac gtcaccaact cttccttgag ccagaagggc
     3721 gcaatactga ggaagtctat gttcaaggac tttcaaccag tctgcctgag gatgtccagc
     3781 gtgacttggt tcattccatc aaaggtttgg aaaatgcaga gatgatgcgg acaggttatg
     3841 ctattgagta tgatatggtc ttgcctcatc agttgcgtgc gactttggaa accaagaaaa
     3901 tctcaggtct cttcactgct ggtcagacaa atggaacgtc aggttacgaa gaggcagcag
     3961 gccaagggat tatcgcaggt atcaatgcgg ctctaaaaat ccaaggcaag cctgaattga
     4021 ttctaaaacg aagtgacggt tatatcgggg tgatgatcga cgacttggtg accaagggaa
     4081 ccattgaacc ttaccgtctc ttgaccagtc gtgctgaata tcgtctcatt cttcgccatg
     4141 acaatgctga tatgcgcttg actgagatgg gccgtgagat tggccttgtg gacgatgaac
     4201 gctgggctcg ttttgaaatc aagaaaaatc aatttgataa tgagatgaaa cgcctagaca
     4261 gtatcaaact caagccagtc aaggaaacca atgctaaggt tgaggaaatg ggcttcaagc
     4321 cgttgacaga tgcggtgaca gccaaggaat tccttcgccg tccagaagtt tcttaccaag
     4381 atgtggtggc cttcatcgga ccagctgcag aggaattaga tgacaagatt atcgaattga
     4441 ttgaaacaga aatcaagtac gaaggctata tttccaaagc catggatcag gttgccaaga
     4501 tgaaacgtat ggaagaaaaa cgcattccag ccaatatcga ctgggatgac atcgattcta
     4561 ttgcgacgga agctcgtcag aagttcaaac tcatcaatcc agaaaccatc ggccaagcca
     4621 gccgtatttc gggagtaaac ccagcagata tttctatttt gatggtgtat ctggaaggta
     4681 aaaatcgtag tatttctaaa actcttcaaa aatcaaaatg atacgtcgta ggcttcttac
     4741 gaatgagttc aaagcttggc tttgattcat ctccaacctc ccatagttcc ccgaactatg
     4801 ggagctaact caagttatgc attttcctag ccttctggtc tgattttcat tgagttttaa
     4861 tctaaaaaga aagcatagag aaaaacagct ccgaggacgg ggctgttttg ttgatttgta
     4921 ctcaatgaaa atcaaagagc aaactaggaa gctagccgta ggttgctcaa agcactgctt
     4981 tgaggttgtg gatagaactg acgaagtcag taacatatat acggcaaggc gaagctgacg
     5041 tggtttgaag agtattattc ttcatctggt gtgaggatca tcgggatgat gatcggttca
     5101 cgttcggtat tttcatagag gaaggggcga atagcgttga caatggcacc attgacagat
     5161 tgcacgctag catccttatt tttcagtgcg atacgaatgg cattgaagag gatacgctgg
     5221 ctttgacgaa tcaagtcgcc agactctctc atgtagacaa agcctcggct gaggatgtct
     5281 ggaccagata gaatcatctg cgatttgaag tcaacagttg cgactgccag aacgacaccg
     5341 tcttcagata gatcgcgacg atctttgagg acagctgcgc caatttcacc gatacgattt
     5401 ccatcgacat agatatcttg ggcgttgaaa tggcctgcga tacgagctga gtcagcagta
     5461 agggcaagca catcgccatt gctcatgata aagatattgt ccttctcaac accagtatcc
     5521 actgctagtc cagcgtggac tttttgcatg cggtattcac cgtggacagg catgaagtat
     5581 tttggcttaa tcaagcagag catgagtttt tgctcttgct gaccaccgtg tccagatgta
     5641 tggatattgt tcactttacc gtggataact tcgacaccag cttcagaaat gatgttaatc
     5701 agcttgttga cgctagtagt gtttccaggg atgggactag aagagaagat aacggtatca
     5761 cctggttgta attgtacttg acggtgggtt ccgttggcga tacgagagag ggctgccata
     5821 ggctcaccct gactacctgt acagaggata agaacttctc ctgcaggata atctttgatt
     5881 tcatttggct cgataaaggt tcccttagga gctttgatgt agccaagatc gattccgttg
     5941 acaatggcct tttccataga acgaccaaag accgcaatct tgcgtccagt cttaacagca
     6001 gcttctgttg cctgctggag acggaagata tttgaggcaa aggatgcaaa gatgatacgt
     6061 ccttcaatac cttggataat cttcataatg gactgaccaa cgactttttc agagttggta
     6121 aaggttggta cttccgcatt tgtcgagtca gacaggagac agagcacgcc ttcttcacca
     6181 agcgcagcca tacgatgcaa gtccgcaggt tctccaactg gagtaaagtc gaacttaaag
     6241 tcacccgtac agacgatttt cccttgagga gtatgaatga caatccccaa aggctctgga
     6301 atagagtgag tcgttctaaa gaaagttgcc ttgagatttt taaaggtcaa ctcggtgttg
     6361 tggttgattt cgtaaagttt ggcgttgcgc aagaggccgt gttcttcgag tttcccacgg
     6421 atcaaagcca aggcaagcgg tccagcataa atagggacat ttgcttgctt gagtaggaac
     6481 ggaatcccac caatgtggtc ctcgtgtccg tgtgtgatta aaacagcctt gacgcggtcg
     6541 atattgtcta cgatgtaaga gtagtcagga atgacatagt cgataccaag caagtcatct
     6601 tctgggaatt taatcccagc atcgacgatg ataatctcgt cttggtattc aattccgtaa
     6661 gtgtttttcc cgatttctcc tagaccaccg atggcaaaaa caccaacttc ttcaggttta
     6721 agagtgtagg ccatattaga actccgtaat ttcgaaggcg ccagtttctt tttcgtaatc
     6781 gagcaatttg tcagacaaga gttcgatata ttcgatattg tactctgggc gattttcttc
     6841 gacaagttgg cgagcagtga tacggccctc aagttctgag ctggtatcga tgtctaggta
     6901 aagcgcgcgt gttgtttcac ggcgtgggct acgttctttt gtttcttgat aaaaaacttt
     6961 gtaaatcata tagttccttt ctatttacag gtcagcttat tccaaacttt tagcagatat
     7021 ttgcttgatt tcattccatt ttgtgtctag attgaccttg attcgttaca attatttcaa
     7081 ttataccaca aaatgaaaaa ttagtaaaag acggaaacga gaaagttagg ggacgatttc
     7141 tttggtaatc gtttgcaaaa ataaagaaaa tgtattatgt tgataacgga agtgaaattt
     7201 attgcttgtc ataattccat atagatttta agtcaaggag gttgccctat gtataactta
     7261 tttgcttttg ctatcggagt tcgtttgtta acttttatcg tttttgttgc ttgcgtttat
     7321 ggaggaaatc ttctatttgc caaactggaa cgatgacaaa ccaagttctt gtggaaaatg
     7381 acctttgtga ctctctactc gctttttctc ctccttgtaa cctatgtcgt ttggtttgta
     7441 ttttactttg gattaaatgc ttagatgccc tgctcatgct agggcatttt tgtttggaga
     7501 taagaagaca atagatttac gatacgaaaa gtccacccca tctatccaga tgaggcggtt
     7561 tttgtatttt ttagaaatga catgataatg gtattttcag agcttattag ttttatggta
     7621 atcattcttc tgatcaaaaa tagagttgaa gcataaaaat aaaacaatac aaacagataa
     7681 atcaattggt aaagggatag tagtaatgtt caaatcattg agaatgctga gcaaactgta
     7741 agagatgaag acaataaaat ttatccttat aaaaatatgt ttcttatcta gcatgactta
     7801 ccaaactttt tacgaaggtc ttttccaatg gtataacctg ccataaataa agcgatacca
     7861 acacctacac caaagccacc cttgatttct tgcaattcct tattagaaat ttcacgatag
     7921 ttgttcaaat ctttcatcat attaatctcc tcctaaaaaa taaccagctg ccaaaccaga
     7981 acctataagt gctgttccac ctgcaatagc cttccaagat actgctactc caaagataac
     8041 caagggagcg agaccgccat caatatctga taattcattt tcagataagg ataaaaattg
     8101 attgtcaaga atgtcaaaat ttgtcattga actttcctcc ttttttcttg ttcactttta
     8161 tattcggaaa agaaaaggaa aagtgagcat ttttttaaat tatttttagt taagtgaggg
     8221 cactcttgtc tgggggcaaa gaaaattccc atgtgccagc ttttgtagta taatagtaag
     8281 cagacaaaaa gataggaatg tgttatgaaa gtattagctt ttgatacgtc cagcaaggct
     8341 ctttctctgg ctattttaga ggataagcag gttcttgccg agacgacgat taatattaag
     8401 aaaaatcaca gtattactct tatgcctgcc atcgattttt tgatggcaag tttggattgg
     8461 acacccaagg atttggaccg aatcgtggta gctgaagggc cgggtagcta tacaggcttg
     8521 cgaattgcgg tagcaactgc taagacctta gcttacaccc tgaacatcga gttggttggt
     8581 atgtcgagtc tcttggctct ggtgccccac caacaagaag gtttgtttgt ccccttgatg
     8641 gatgcgcgtc gcaataatgt ttatgcagga ttttatgaaa atgctaaacc tgtcatggca
     8701 gaagcgcacc tatcttttga agaggtgcta gaaaaagtca agggtactag tcaggtaacc
     8761 tttgtcggag aagttggccc ctttgttgag cagattcaaa aacacttgcc aaggactgat
     8821 tacaaagaaa cattgcccaa tgcagctaat ctagctcttt tggcctggga caaggaagca
     8881 gactccttgc atgattttgt gccgaattac ctcaaacgag tcgaggctga ggaaaactgg
     8941 ctcaagaacc ataccgagtc tggtgagtcc tacattaaac gcctatgata gaaatcaagc
     9001 gaattcaaca acagcctgac ctagctcaag ccatctacgc tgttatagca gctgtttacc
     9061 tagtcagtcc ttggactctg gagcaaatcc aagcagatct gtcccaagac cagacttggt
     9121 atgcattggc ttatgatggg gcagaagtga ttggatttct agctgtgcag gagaatcttt
     9181 ttgaagcaga agtcctgcaa atcgctgtca aaggagccta tcagggtcag ggaattgcgt
     9241 cagccttgtt tgctcaattg ccgacagata aggagatttt cctcgaagtc agaaagtcaa
     9301 atcaacgagc gcaagcattt tacaagaaag aaaaaatggc ggtcatcgct gagcgaaagg
     9361 cctactacca tgacccagtc gaggacgcca ttatcatgaa gagagaaata gatgaaggat
     9421 agatatattt tagcatttga gacatcctgt gatgagacca gtgtcgccgt cttgaaaaac
     9481 gacgatgagc tcttgtccaa tgtcattgct agtcaaattg agagtcacaa acgttttggt
     9541 ggcgtagtgc ccgaagtagc cagtcgtcac catgtcgagg tcattacagc ctgtatcgag
     9601 gaggcattgg cagaagcagg gattaccgaa gaggacgtga cagctgttgc ggttacctac
     9661 ggaccaggct tggtcggagc cttgctagtt ggtttgtcag ctgccaaggc ctttgcttgg
     9721 gctcacggac ttccactgat tcctgttaat cacatggctg ggcacctcat ggcagctcag
     9781 agtgtggagc ctttggagtt tcccttgcta gccctcttgg tcagcggcgg acacacagag
     9841 ttggtttatg tttcggaggc aggagattat aagattgttg gggaaacccg tgatgatgcg
     9901 gttggtgagg cttatgataa ggtcggccgt gtcatgggct tgacctatcc tgcaggtcgt
     9961 gagattgacg agctggctca tcaggggcag gatatttatg atttcccccg tgccatgatt
    10021 aaggaagata atctggagtt ctccttctca ggtttgaaat ctgcctttat caatctttat
    10081 cacaatgccg agcaaaaggg agaaagcctg tctacagaag atttgtgtgc ttccttccaa
    10141 gcagcagtta tggacattct catggcaaaa accaagaagg ctttggagaa atatcctgtt
    10201 aaaaccctgg ttgtggcagg tggtgtggca gccaataaag gtctcagaga acgcctagca
    10261 gccgaaatca cagatgtcaa ggttatcatc ccccctctgc gactctgcgg agacaatgca
    10321 ggtatgattg cctatgccag cgtcagcgag tggaacaaag aaaacttcgc aggctgggac
    10381 ctcaatgcca aaccaagtct tgcctttgat accatggaat aaagagtggc tctttgtcaa
    10441 gtgtagtggg taggcgaaaa gctacaatct ggagagtacg aaattcgtac tctctttttt
    10501 gatgttcaaa gtcatcaaaa tccgtttttt aaaattgtta aagttccgga aaccaaaggc
    10561 tttgcgcttg ataatcttaa tcaaattatt ggtcgcttca agtttagcgt tggaataagg
    10621 cagcttaagt gcgttgataa tcttatctct atcccttaaa aaagtccaaa agaccgtttg
    10681 aaaaagcgga tgaaccgttg gcagttcttg ctcaatcaat ccaaagaaat ggtcggcatt
    10741 cttctcttga aaatgaaaga gcaggagttg atagagttcg tagtgaacct gtaatccctc
    10801 agagtaagaa agcagcttat ctcgtacttc ccgatgggtt aagtgcattc gaaacgtggg
    10861 ctgatagaat cgtttctgac agagcttgaa gctatactgg tgtagtaaat cagtccagtg
    10921 gactgattta gcccgagcct agaaacgaaa aagcgagggt tccaaaagcg cttgagcgcc
    10981 cgatactcca aggattttcg gtcaaattgg ttcatgattt ggattcgtac tcggttcata
    11041 gctcggctca gatgttggac aatgtggaag cggtcaagaa caatcttcgc ctttggaaag
    11101 agttgcttag cgagccgata ataagggctg tacatgtcca tggtgatgac ctcgaccagc
    11161 tcccgaacct ctctctgata gcgctggaaa tggtttcgaa tcaccgcatg agttcgcccg
    11221 tctaaaattg cgaggatgga tttggactca aaatcttggg caatgaagct cattttgctc
    11281 tttttgaagc tatactcatc ccaactcata acttttggca acttggtcca atcggtttca
    11341 aacttaaatt ccctcagttt tcggataacg gtggaagttg agaccgccaa tcagtcatag
    11401 actgcttttc aaggaggagc tgagcgattt tttgtctcac catgttggaa atctggcaat
    11461 ttttcttgac aatggatgtt tgagaaacga ccaccttaag gcaattcttg cactgaaagc
    11521 ggcgcttttt gagatgcagt accgtgggta aaccctgaca gtcgagaagc ggaattttag
    11581 aggctttctg gaagtcgtat ttgatcatct tcccttgaca atgaggacaa ggaggagcgg
    11641 gggaatccaa ctttgcctga acgactagat gggtttggta tttcagaaca gacaagattt
    11701 tgatattttt gtcttccaat ccgagcaaat ctgtggtatt cttaagttgt tccatatgaa
    11761 ccctttctaa tgagttggtt agacgctttt cattataggt catatggggc tttttttcta
    11821 caagaaacga ccctataatt cctggggtgg gattacccac tacagaaatt atagagccaa
    11881 agcattccaa agtcttgtct gactctggaa tgttttctgt tcacagttgt tttgtaactg
    11941 cctaataagt aaccgcgcta taacgaggta tctaccgaga ttgtcaattc tccagtatac
    12001 tgttataaaa aacaaaactg gaggattttt ttatgtcccc ccatcgtccc atcgactgtt
    12061 ccgtagctgc ccaataacgg agtatagtcg gctgaaacaa gaataggaca aaagtgcctc
    12121 aagaaaagca tcgtaatttg acaatattat tctgagatgt ttttgatgta agcccatatt
    12181 ttctcaatgg gattatactc gggtgaatag gtaggaagtg gtaacagtct atgccctgct
    12241 ccttacacat gttcattctg tgaaaccttg catggtccat aatgataagg gatggtgtat
    12301 ctaaagtagg tagtaagaat ttttggaagc aagcttcgaa aaagtcactc gtcatcgtat
    12361 ctttataggt catcggagcc atagtatatt gaaacaaaaa agggcattag tacttctata
    12421 acagtatcgc aatctctggt gtgcgttgtc tcgatcttaa ttcaaataat tatatcttct
    12481 tccagagaga ctaactgcct gctcaaggct cgatcatatt cgagataaaa ataggtctca
    12541 acccctgtct cataaatata aataggagtc aggtagctta agtgattcaa ttctttaagg
    12601 aaccgattta ctttttctgg gtcttgttcg cagtaggtac ggctcttttt tagactatat
    12661 cccatagcct ttagagcgta atgaatagtt gttggaggac agttgaattc agcagctatt
    12721 tcagtcaaat aagcatcggg atgagtttca atatagatct ttaatttatc tctatcaact
    12781 ttttcaatta atagtggaag ttttcttgaa gttagtgtat tgaaacgttt ttatacagtg
    12841 ctaaaatttg aagtgtagtg cagatgcatt tgtaatagta ttatagcaat tctttggaga
    12901 aggtcgagac aagataaaat aggtatcttt gagatataag catgatttac tataaaatta
    12961 ttgagttatt cataaaaatt tctctatcaa atatcataat gcgtcgttta aggagatggt
    13021 tacaatgcaa tatagttgtg gaaaaataaa tattaatatc cctgatggat atggagacat
    13081 taaggatata gtgttttcgg ctcatattat agttaggtat aataatggac attgtggagg
    13141 tatagatccg catataattg gactttgtaa acagcagatc agaaggatgt ctctatatcc
    13201 tattttgata atcgtatcta gagattcaaa ggttattgat gattataaaa atttagatat
    13261 tgcctatgtt gattgtactc aatgttcaaa taattttgaa actgccttac acgttaaaaa
    13321 tattttaaaa ttattaaaaa tccaacttat acactgtcat ggctactcaa ctaattattt
    13381 tttatatatg ttaaaaaaac ttgacaagaa tggatttgga aaggttaaga cagtgataac
    13441 atgccatgga tgggttgaat ataacttaaa aaagaaattc ttgacttatt ttgatttttg
    13501 gacatattct atgggagatg cttttatttg tgtatctgaa actatgaaaa aaagattgga
    13561 gagtataata aaaaataaga agatagttgc aataaataac ggaattaatg tatcaaatag
    13621 cgatttagat gtagtaggtg ttcaagactt taaaaaagaa ttttgtattc caaataacaa
    13681 aaaaatcatt tgttatgttg gaaggttgga tccagaaaaa aggccggata gattccttga
    13741 atttgcagaa aaattatttt tagtcagaga agatgtgatt tttattatgg ctggaaatgg
    13801 tagtatgtgg gctgctttga aagaaaaaat ttgccatttg aaatgtagag ataatttcag
    13861 gttacttggt gaaatctatc cagctactat agtttaccaa atatcggatt tattgtatat
    13921 tccttatgat acagaaggaa tacctatgtg tgttttagag tcaatgtcac aaggaactcc
    13981 ggttttagct aataatgttg gcgggttaag tgaaattatt gaacataggg ttgatggatt
    14041 tttatttgag aaggaagatg ttgagggagt gtgtgcttgt gctaattttt tactcaatga
    14101 ttctgagtat ttgaaatata taggtgagaa tagtaaatca aaaataagaa aacatttttc
    14161 tgtgcaaaaa atgtttgtag aaaccatgag agtatatgat gaattattag agaagagtag
    14221 tcatggatag gaatatagat caagaattag taagtattat aataccaaca cataataggt
    14281 atgaatctct gattagagct gtgaaaagtt gtttacatca aagttataaa aatatcgaag
    14341 ttataattat tgatgataat tatagtaatg taaatttaag aaataaaatt atccatcaat
    14401 ttggctatac caatcataga attaagttaa ttttaagtaa tgaagattta ggtgcaacta
    14461 atgccagaaa cataggtata aaaaattcta gaggtaagta tatatcattt ttagacgatg
    14521 atgatgaata tatgccagat cgaattttaa agttgatggc ttgttttaaa aagagtagaa
    14581 tgaagaattt agctttagtt tatagttatg gaataataat ttatccaaat ggtacacgag
    14641 aagaggagaa gaccgatttt gttggaaatc ccttgtttgt tcaaatggtt cacaatatag
    14701 caggtacgtc attttggttg tgtaaaaaag aggtgctaga attaattaat ggttttgaga
    14761 aaatagattc acatcaggac ggtgttgttt tattaaaact acttgctcaa ggataccaaa
    14821 ttgatatagt gcgagaattc ttggtgaatt actacgctca cagtaaagaa aacggtatca
    14881 ctggagtgac acaaaaaaca attaatgcag atgaagaata ttataattac tgtaggaaat
    14941 attttaattt attgagtttc aacgagagaa tattggttac aaagaaatat tattctttaa
    15001 acataaagcg gttactatta ataggagaca aatgcaaggc tttaaaagta atcaagaagg
    15061 caagagaaga aaaaattttt aacgaatttc ttttttgaaa tacatgttat tatattattt
    15121 tggttttttc tattgtatat atgacaacta tgttcaatta aaatttagaa agtgagaaac
    15181 tattgtgtat actattataa aatcaaatat aaaaaaattt agtttattaa cgatatttat
    15241 tgttgctggt caattattgc taatttatgc agcaactatt aatgctctgg tgttgaatga
    15301 attaattgcg atgaatttag agcggttttt gaaattgtca atctaccaaa tgattgtctg
    15361 gtgtgggata atattccttg actgggtagt gaaaaattat caggttgaag tgatccaaga
    15421 gtttaatcta gagattcgaa atagagttgc cacagacatc tctaactcta cctatcaaga
    15481 atttcatagt aaatcatcag gaacatatct ttcgtggcta aataatgatg ttcagacttt
    15541 aaatgatcag gcttttaaac aacttttttt agtaataaaa ggaatttctg gtactatatt
    15601 tgcagttgtg actcttaatc actatcattg gtcattgact gtagccacct tgttttcatt
    15661 aatgattatg ctacttgtac caaaaatctt tgcatcgaaa atgcgagaag ttagtctaaa
    15721 tttaactaac caaaatgaag cttttttaaa atctagtgag actatattga atggatttga
    15781 tgtgttagcg tccttgaatc ttttatatgt attgcctaag aaaattaaag aagcaggaat
    15841 tttattaaag atggttatac aaagaaagac aactgtagaa acgttagcag gcgctattag
    15901 cttctttctc aatatttttt ttcagatatc tctcgttttt ttaacaggct atcttgcaat
    15961 aaaaggaata gtgaaaattg gtactattga agcaatagga gcactaacag gtgttatttt
    16021 tacagcgcta ggtgaattag gaggtcaatt atcctctatt attggtacga agcctatttt
    16081 tttaaaattg tattcaatta atccaattga gtcaaataaa atgaatgata tcgaaccaaa
    16141 tgaggtgaat agagattttc cgttatatga agcaaaaaat atttgctata agtatggaga
    16201 taaagaaata ttaaaaaact taaatttttg ttttcaacgt aatgaaaagt atttaatttt
    16261 aggtgaaagt ggaagcggga aatctacatt attaaaatta ttgagtggct ttttgagaga
    16321 ttatagtgga gaattgcgat tctgcgggga tgatataaaa aaaacctcct atttaaatat
    16381 ggtttcgaat gttctatatg tagatcaaaa agcttatttg tttgaaggta cgattagaga
    16441 taatatttta ttggaagaaa attatactga tgaagaaata ctacagtctt tagagcaagt
    16501 tggtttgagt gtaaaagatt ttcctaataa cattttagat tattatgttg gtgatgatgg
    16561 gagattactg tcaggagggc agaaacaaaa aattacttta gctagagggc taattagaaa
    16621 taagaaaata gtattaattg acgagggaac ttctgctatc gataggagaa cttcgttagc
    16681 gattgaacgt aagatattag atagagagga tttgactgtc attattgtta cccatgctcc
    16741 gcatccggaa cttaaacaat attttactaa gatatatcaa tttccaaagg attttattta
    16801 agaatatagg ggagggaaac atgagattct attgtgaagc ttatgaggta attactgaag
    16861 agaaaaaagt atcatttttt tatgtagatg aaaaaccctt aaggtatctg ttatttgact
    16921 atatatttct actagttcta gctaaaaaaa atatcccaat cttatgaact gcaccccaaa
    16981 agttagattt attctgtcta acttttgggg tgcagttcat tttgcatagt tttggcattc
    17041 atcctagata tccatataaa atgtctgaga ttgttgaaat gtctaaaaaa atatcagatc
    17101 taaacgataa aaaagaattt cacaaaaaga actgtgagtt gaggtttcaa gatagtgttc
    17161 ttgataacat aaatagtgtc ccgggtacaa ctcatttatt tagttgttta aatattcaaa
    17221 tattagtaaa aattatttta tatatttttc gatacaacag ttgtatgaaa atatttaatt
    17281 ttagagataa agagcttatc ttttttaata agattgtaaa tgggctgata caaaatattg
    17341 aggagaattt agaggatgat attgaaagga tattgaaata tttatatata tgtttattta
    17401 acgaaatatt cattattaag aataaggtga atttttttga tgatgtggaa tttaatcaga
    17461 cacttagtga gtttttagat aaattgtaga gggaatggtt atgagtaaca atactaagta
    17521 tatcttttta tctccacatt tagatgacgc aattttttcc tgtggtgatt atatttcaaa
    17581 attaacttca gaaggagaaa ttgtacttgt tattactata ttttctggtt accctttgag
    17641 ccaacagcta cagccctctg ctaagcaatt tcataagttg tgtaaccttg ggaaatatcc
    17701 gattgaagaa aggaagaaag aagacaggtt agcttgtgaa cgtctacaat gtgattttag
    17761 acacttatcg tactatgaat gtctctatag gaaagataga aatggcaatt ttctataccg
    17821 tcatatctat agtgaattaa aaaatgagga cacattaaag aatgatatca taaaagagct
    17881 gttaatgcat ttagacgaca aatgtgtcgt atattgtccg ctttcacttg gtgaccatgt
    17941 tgatcatgtt tttgtgaata gtattggaag ggcgcttgaa tttatgcgtt ataaagtaat
    18001 atattatgag gatttcccat atgtaagtga tagtagtatg gttagttata tgggaaaaac
    18061 taaagaatta aaaatatatc aagaggaact tgatgaaaaa cattatattg atagaatatc
    18121 atcaatattg tgctataaat ctcagatttt gataatctgg aaatcagttg aaaaactttt
    18181 aaacaatatt aaagagttgt atttaaggaa tggggcagct tattctatta tattttggat
    18241 taagaaataa ggaagtagtt ttatgaatat agcagtaatt ggtttggggc atgttgggct
    18301 ggcctacgcg ttactatttg catctaaata taaagttgtt gcatatgata tagattctgt
    18361 aaaaataaat aatttaaaaa agggcattct tccatctaaa aatgaagagc ttatgaagtt
    18421 tttttgcgag aataacttaa atattacttt ttttgataca ttttctgaaa ttaaaaataa
    18481 tattgattat tatattattg cgcttccgac agattatgat gagaaaattg gtagttttaa
    18541 tacatatgaa atcgaacaaa cggtatcgaa gattctgagg gtaaaaccta atggaaagat
    18601 tattttaaag tcaacagttc cgatcggctt ttcaaacaaa ttaaaaaggc tgtttgatac
    18661 aaaaaatatc atttttgtcc ctgaattttt gagagaaggt tgttctatat atgataattt
    18721 atatccaagt cgcatagttg ttggaaatga gacagttgaa ggaagaaaaa ttgcagagtt
    18781 gttcctttcg attagtactc atagtactgc caatattaaa aatgttatgt tagtttctcc
    18841 tactgaagca gaagcaatta agcttttttc taacacattc ttagctctcc gtgttgcttt
    18901 ttttaatgaa ctagattctt ttgctgagag gagaagttta aatgctgaag ttgtaataaa
    18961 aggtgtttgt ttatatccaa gaattggaaa tttttataat aatccttctt ttggatttgg
    19021 aggatattgt cttcccaaag atactaaaca attaaaaaaa gaatttatag aaataaatgc
    19081 cccagtgata gaagcgattg atatttcaaa cacaaataga aaacagttca tagttaaaca
    19141 aatattggaa cgaaagccaa agatagtagg aatatataaa ttggggatga aatataattc
    19201 agataattac aaagagtcag ctattttaag tataattaat gaactattga ttgtcggtat
    19261 aaaaatttta gtatatgaac caaatttaaa cgttagtata gataacgtaa tttttgaaaa
    19321 gaattttgaa ctatttacaa aacaaagtga tctaattgtt gcaaatagat gggatagggg
    19381 ccttgaagct tataaagata aagtttacac aagggggatc tggataagag attaactatt
    19441 gatattaaaa aggcaataat ttataaaatt tgtacaaaaa aatgttaaat tttcacattt
    19501 tcatagtata ctgtttaata gaaagtaggt tctttgtaac cgctccatta taaaatcctt
    19561 tcactcttcc ggtatactat taggaaaaac ataactggag gatattttga gctcacacct
    19621 catcgttcca gtggctgttc cccaagctcg tgtactgccc aaaaaagtta gacattctat
    19681 ttagaacgag gattgagttc tgtattgtac aaggctcggt ccttttagag tcagcttaag
    19741 gctggctttt ttattttttc taactatcag aatattttga caaatgaaca caaataatga
    19801 tataatatgc aaaagctagg aggtggtagg atgattgaaa aaatggaact gggggaattt
    19861 tacaaggaat tacgtttggc gagaaagctc aagcagtcag atgtggcttg tgacgggcta
    19921 acagcttctc agttgtccaa gtttgagcta gggcagtcca tgttgtctgc tgataagctc
    19981 atattagcca tccaagggat caatgtgacc tttgatgagt ttgggcacaa gctcaacaac
    20041 tatcaagaat ctccacatat gcagattggt agaaaggttg tggatcgctt tgctcatcaa
    20101 gatatagctg gcttagagca actgttggag gaagtcgagc aagaacagat ggcgcagacc
    20161 tatcgtcgtt tgaatgccat cgtgattaaa gatgccatcc attcactaaa taaaagctac
    20221 ccactagcag aggaggatag cgagtttttg accacctatc tctatgctat cgagtcttgg
    20281 acctggtttg aactctatct cttttgcaat accatgccct tcttgagcaa tcaagatctg
    20341 atttttttat caacctcctt actcgaaaaa tccaaagaat ttaaagagtt agtacacaat
    20401 cgattgtata tgaagcaagg actcttaaat atcttatcag aactcatgga gcgaaaactt
    20461 ttctcctaca tcccaatctt cgaagccgag ttggagagga tgttacgacc gtatgatgtt
    20521 tttgaaaaag tatcgtggca atttttaaag aagatgagtg tctttcttca aacaaaggga
    20581 agcaatcaaa aagagattga acgctttatc caatctctgc aggtattaga aaatccacaa
    20641 ttaatagccc tttttgaatt gcgtttgcag caatacaaaa agcttatcga ttagttagaa
    20701 atggcaaaat aataataatc tcagcaacga ttttcaataa tgttaaaatt tgtttcttca
    20761 tatttctcca ctcctcatta gtagtaactt tattatacca gagaagtaat caaattcacc
    20821 aaaatcgcaa atctgaaatt tctataagaa aaaatatcaa atatgcgatt ttctaaaata
    20881 agccaatgtt cgtgttatac tgtacttgta aagcacttga agcaaatcct aggtcgcaga
    20941 agtggtttac aaatgaagat aattgaagga gtgtaaaaga tgttaaattt acaatttgca
    21001 gaaacaatgg aattgacaga agctgagttg caagatgtta gaggaggcaa cctcgtaaat
    21061 tctatgggag gtggtggaag aagtggtata tctggttggg gcgtcccagg aatttaccct
    21121 ggttggggca atcaagggat gagtcctaat cgtggagctt ttgattggac tatagattta
    21181 gcagatggat tgtttggccg ccgtagaaga taggctctta taggagataa taggatgaag
    21241 aaaatgaaag aagtgaaatt tcacctagca actggcttgt tgattttgac ttattacctc
    21301 atttttaatg tcacatcaga cttagatttt atggttgctt tgtctgataa tatgtactat
    21361 gtgttccaag ttttattggt acttattctg ggaactatag ctacaattgc ttttgtcaaa
    21421 agtgaacatt ggaaagagtg tggtcgtttc cagtttcgtt ggtcttacct gggtgttttc
    21481 cttctttctt ttttcttatt gttcgtgtgg gcaaatctaa caacctatat ctttcctcgt
    21541 acccagaatg gaagtacagt cgtagaagta gccaccaatt taacaggaat tagctatttt
    21601 gttacgcgaa tactttatac tagtattatc gcacctgtat cagaagaggt tgtttgtcgt
    21661 ggtcttttga tgacaagttt atctaaagtt aagagatact atcttgatgt tcttgtttcc
    21721 gctgccatat ttggcgctat gcatgttttg cagtatggtt ggataacgac agatttcata
    21781 aagtattttg gaatgggctt gatattttgt atgatgtttc gctacacccg atccatctat
    21841 tgggctatag ctctgcatgc ttcatggaat agtttcttac tcattgttac tttattggta
    21901 tttggatatt agaaaggtga taatatgaaa aagataatct cacaccgcta ctttattata
    21961 gtttttctac tagttattgc tgaccagaag ttcagtgttc tagttttacg cagcgacctt
    22021 gttactgggc tatctgactt tgcctattat ctgtcggata tgatgttgaa ttttcttgtg
    22081 gttttatttg ctcttattgc tatgatttgg tcggggaaat ggcagaaaat caatagtaga
    22141 aagtttaaag gatcctatct tttctattcc ttcctagctc tgcttgcttt tgttgcttgg
    22201 aattttgtca ccttttttct tttcccacct actcgaaatg aaatttctta tcaacatgct
    22261 gctcctactt ttacaggagc tacggcattt ttgatgtatt ttttttatcc tgtgattgca
    22321 ggtcccattt ttgaagacat gatttatcgt ggattagtga tgactgctct ggaaaaagga
    22381 aagaaatggg ggctagatgt acttggttcc gctgttttat ttggggtctc gcacattagt
    22441 aatcacggtt gggtcttgac agactttgtc ttctatatgg gtggaggtct tatatttgca
    22501 gtcttattta gaatgacaaa gtcaatttat tggcctattg ggctgcatat agtctacaac
    22561 ggcattggtc agcttttgat gttactgtaa ttttggttgt tagtagtatc gcggtctatt
    22621 tctggggaaa gattcccatt tgaacttaag aaggagttgt gatgaaagta tttcttcaaa
    22681 atagagattt taggcaatta actatcaacc agtggatttc aacgcttggg gatacgattt
    22741 tttatctggc ctttctgaat tatgtggcag atgcgtcttt tgcacctttg gcgattttac
    22801 tcattacgat ttcagaaacc cttccccaaa ttttacaaat ctttctggga gttttggcag
    22861 attttcaaca tcatcgtgtc ttgaaataca cagtcattag ttttgcaaaa tttttgcttt
    22921 actctatcgt ttctttatca ctttcagggc agtctttctc cttgttgcta gtagcattta
    22981 tttgtctgat taacctcttg tctgacacat tgagttactt ttcaggagcc atgctcactc
    23041 cgattttcat tagaattatt gggcaagacc atctggcaga agctattgga tttaaacagt
    23101 caactgttag tttagtgaaa acaatcagta atattctagg aggagtctta ttaggtattc
    23161 tatccatcca gtttatttcc ttgctgaacg ctcttacctt tttaatcgca tttttaggta
    23221 tcctcttcat aaaaactgac ctcttgaaag tagaaaaaac gattagctat caagaaggac
    23281 tctctgtaaa atccttttgc cagcatttgc tccaatcatc gaaattgata tggaatatga
    23341 ataaggtgct cttggttttg tttattatct ctactagtca agcagtgata aatgttacag
    23401 ttcctgtctc tactctattt ttgaggaatc aacccttttt gaatttacaa acaggtcaat
    23461 ctcttgcctt gctatccact tttgaactgt cagccctgat tgtcggaagc cttgtaagtg
    23521 gctatctgca acataccatt tccataaaaa cagctctcta tgcctcactt gtcatccagt
    23581 tgcttcttct agtaggattt gccacagttc gttttgactg gattctcatc tttagtacct
    23641 tggatgcctt tttcgcaggt gttctctctc ctagattgca agaactcgtt tttaaacaaa
    23701 tacctgagga gtcaatggga gcagttcaat cctctatcgg tgccattacg gttgttttac
    23761 ctagcttatt tacaatagct ttggtaacca ttgctactag ctttggaact ctggcagtta
    23821 gctttgtttt attgctattt cttctagttg cctttgttat gcttctgaat attcgtgaaa
    23881 gtatttagtg gagaatttct ataatatatg tttgagactg gattgccagc ctttttatga
    23941 tggtcaaaat caacagactt ttttctcttt tctgaatgtg ttataataga ctgaatctaa
    24001 aatagtac
//
LOCUS       DBERPV010000032        22009 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.32, whole genome shotgun sequence.
ACCESSION   DBERPV010000032 DBERPV010000000
VERSION     DBERPV010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 22009)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22009)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22009
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.32"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..133
                     /gene="tnpB"
                     /locus_tag="ACL8C7_001582"
     CDS             <1..133
                     /gene="tnpB"
                     /locus_tag="ACL8C7_001582"
                     /inference="COORDINATES: protein motif:HMM:NF017528.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGS1395742.1"
                     /translation="DRFKALYWDGQGFWLLYKRFENGKLTWISTEKDVKALAPEQVD"
     gene            complement(324..611)
                     /locus_tag="ACL8C7_001583"
                     /pseudo
     CDS             complement(324..611)
                     /locus_tag="ACL8C7_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            593..1122
                     /locus_tag="ACL8C7_001584"
                     /pseudo
     CDS             593..1122
                     /locus_tag="ACL8C7_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_050084071.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1197..2117)
                     /gene="cysK"
                     /locus_tag="ACL8C7_001585"
     CDS             complement(1197..2117)
                     /gene="cysK"
                     /locus_tag="ACL8C7_001585"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HGS1395743.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKLGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(2402..3037)
                     /locus_tag="ACL8C7_001586"
     CDS             complement(2402..3037)
                     /locus_tag="ACL8C7_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HGS1395744.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYASSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            3093..4391
                     /locus_tag="ACL8C7_001587"
     CDS             3093..4391
                     /locus_tag="ACL8C7_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGS1395745.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            4388..5050
                     /locus_tag="ACL8C7_001588"
     CDS             4388..5050
                     /locus_tag="ACL8C7_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HGS1395746.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQFWCKEGVGVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            5130..5678
                     /gene="raiA"
                     /locus_tag="ACL8C7_001589"
     CDS             5130..5678
                     /gene="raiA"
                     /locus_tag="ACL8C7_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HGS1395747.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            5814..7787
                     /locus_tag="ACL8C7_001590"
     CDS             5814..7787
                     /locus_tag="ACL8C7_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HGS1395748.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDHVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            7784..8236
                     /gene="rplI"
                     /locus_tag="ACL8C7_001591"
     CDS             7784..8236
                     /gene="rplI"
                     /locus_tag="ACL8C7_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HGS1395749.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            8280..9632
                     /gene="dnaB"
                     /locus_tag="ACL8C7_001592"
     CDS             8280..9632
                     /gene="dnaB"
                     /locus_tag="ACL8C7_001592"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HGS1395750.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            9634..9900
                     /locus_tag="ACL8C7_001593"
     CDS             9634..9900
                     /locus_tag="ACL8C7_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HGS1395751.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            9989..11335
                     /gene="cbpD"
                     /locus_tag="ACL8C7_001594"
     CDS             9989..11335
                     /gene="cbpD"
                     /locus_tag="ACL8C7_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HGS1395752.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSGG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRI
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      11418..11520
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            11591..11881
                     /locus_tag="ACL8C7_001595"
     CDS             11591..11881
                     /locus_tag="ACL8C7_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HGS1395753.1"
                     /translation="MKASIALQVLPLVQGIDRIAVIDQVIAYLQTQEVPMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            11844..12602
                     /locus_tag="ACL8C7_001596"
     CDS             11844..12602
                     /locus_tag="ACL8C7_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1395754.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            12641..13648
                     /locus_tag="ACL8C7_001597"
     CDS             12641..13648
                     /locus_tag="ACL8C7_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS1395755.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            13648..14376
                     /locus_tag="ACL8C7_001598"
     CDS             13648..14376
                     /locus_tag="ACL8C7_001598"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1395756.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            14495..14953
                     /locus_tag="ACL8C7_001599"
     CDS             14495..14953
                     /locus_tag="ACL8C7_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HGS1395757.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            14955..17387
                     /locus_tag="ACL8C7_001600"
     CDS             14955..17387
                     /locus_tag="ACL8C7_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HGS1395758.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIATLRRNLEERAGWTREDLKA
                     LRQRHRTVADRQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGNTLKI
                     GVKAGQLKFDIA"
     gene            17708..18361
                     /gene="rr06"
                     /locus_tag="ACL8C7_001601"
     CDS             17708..18361
                     /gene="rr06"
                     /locus_tag="ACL8C7_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HGS1395759.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            18358..19689
                     /gene="hk06"
                     /locus_tag="ACL8C7_001602"
     CDS             18358..19689
                     /gene="hk06"
                     /locus_tag="ACL8C7_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HGS1395760.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIYE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVSNILESYQMDYSFLPYEHGMEFKISL"
     gene            19784..20311
                     /locus_tag="ACL8C7_001603"
     CDS             19784..20311
                     /locus_tag="ACL8C7_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HGS1395761.1"
                     /translation="MVLAIILVTFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDSMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGRMKG"
     gene            20391..>22009
                     /gene="pspC"
                     /locus_tag="ACL8C7_001604"
     CDS             20391..>22009
                     /gene="pspC"
                     /locus_tag="ACL8C7_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     LPXTG-anchored form"
                     /protein_id="HGS1395762.1"
                     /translation="MFKSNYERKMCYSIRKFSIGVASVAVASLVMGSVVHATENEGTT
                     QAPTSSNRGNESQAEQRRELDLERDKVKKEVREYKEKKVKELYSKSTKSRHKKTVDIV
                     NKLQNINNEYLNKIIQSTSTYEELQKLMMESQSEVDKAVSEFEKDLSSSSSSGSSTEP
                     EASDTAKPNKPTELEKKVAEAQQKVEEAEKKAKDQKEEDYRNYPTITYKTLELEIAEF
                     DVKVKEAELELLKVKAKESRDEKKIKQAEAEVESKQAEATRLKKIKTDRKKAEEEAKL
                     KEAVEKNAATSEQGKPKRRVKRGALGEQATPDKKDYFEKDFRPAFNKNQQMVAIQESL
                     NKLDDETKTVPDGAKLTGEAGNAYNEVRDYAIKVVSENKKLLSQTAVTMDELAMQLTK
                     LNDAMSKLKEAKAKLVPEVKPQPENPEHQKPTTPAPDTKPIPQPEGKKPSVPDINQEK
                     EKAKLAVATYMSKILDDIQKHHLQKEKHRQIVALIKELDEFKKQALSEIDNVNTKVEI
                     ENTVHKIFADMDAVVTKFKKGLTQDTPKEPD"
BASE COUNT         6936 a         3657 c         4939 g         6477 t
ORIGIN      
        1 agaccgcttt aaagcccttt actgggatgg tcaaggattt tggctactat ataaacgctt
       61 tgagaacgga aaactgactt ggataagtac agaaaaggat gtcaaagctc tcgcacctga
      121 acaagtagac tagcttatga agggcttttc tatcactcca aaaatatagt agatggaaac
      181 tagaatagta cacctctgct tctaaaacat tgttagaaat cgatttgact gtcctgatcg
      241 atttgtccta ttcttatttc attttactat aaatccatca gaaagtcgtg atttctattg
      301 aaatgaggac tttcttttta cactcatctg ctttcaaaaa gcattctagt ccgtctccga
      361 ttaacgatgg actttatcac caccttctcc agtccttgta tgacatcttc caaagttcga
      421 aaggctttat tcttaaatcc acgtttacga atctctttcc acacttgttc aatggggttc
      481 atctctggtg tgtatggagg aataaatgca aagccaatat tagtcggaat ctttaaggta
      541 cttgatttat gccatatagc attgtccata acgagtaaaa gataatcatc tggataagct
      601 tgtgaaatct cctattccta aagccccttt agcgcataac tttggctcag cttctattat
      661 cgctcacacc atccatcaga agtttaatct gaaggtaccc aattatcgcc aagaagaaga
      721 ttgggctagg atgggtttac caatcacacg taaggaaatc tctaatcggc atatcaagac
      781 gagtcaatac tatttggagc ccctttataa cctcttgcga gagagactat tgactcagcc
      841 cttacttcat gcggatgaaa cttcttatag ggtgctagag agtgatagtc agctgactta
      901 ctattggact tttttgtctg ggaaagctga gaaacaaggg attacgcttt accatcatgt
      961 cctaatcgat ttgttcatat cttatttcaa tccattataa atagtgagaa atatctatcc
     1021 tatcttctag aatgtcttcc aaacgtggaa actctcgtaa acaaagaggt tttagaggcc
     1081 tatttaccat ggactaaagt tgtacaagaa aagtgcaaat aagaaatctc cagattagga
     1141 actatccgtg agttctctag tctggagatt tttcaataga cttcgttatt ggacggttac
     1201 aattcataaa gtgctgtaga gagataacgt tcaccgttat ctggtgctag ggcaaggact
     1261 tttttacctg tacctaattt tttggcaacc tcgatggctc cgtagatagc tgcagctgag
     1321 gaaatcccta caaggaagcc ttcttttcca ccaatttcac gtccgagtgc aagagcgtca
     1381 tctgatgtta cacgaacgat accatcatag gctttagtat caagtgtatc aggaataaat
     1441 ccagctgaga taccttgaat tttgtgagga ccaggttttt caccagatag aatagcagat
     1501 tcatctgctt ctactgcaaa aacttgaatg ttagaatttt ctgatttgag tgcatgagaa
     1561 acaccagaaa tcgttccacc agtacctact ccagcaacaa aggcatctaa tccatcttta
     1621 ccgaaagcag ctagtatctc agctcctgtt gttctttcgt gtacttctgg attagctgga
     1681 ttgtcaaatt gaagaggaag gaaaccatca cgttcagcag cgatttcttg agccttagca
     1741 atagcacctt tcattccctc gctaccagga gttaggacga gttcagcacc ataagcttgg
     1801 ataattttac gtcgttctac actcatagtt tcaggcataa cgatgacgac tttataccct
     1861 ttagcagcac ctacccatga aagtccaata ccggtgtttc cacttgttgc ttcaacaata
     1921 gtagaaccaa gtttcagaat accatcttgt tcagcttttt caatcatgct aagggcaata
     1981 cggtctttta cagatgaacc aggattaaat gcttcaagct ttatatagac gtctgcagca
     2041 ccttctggca cgatgttgtt aagtttaaca atcggtgttt gaccgattaa ttcagtaatg
     2101 ttgttataaa tagacatatg aatacctctt tgtataagat atctttagta taacgctatc
     2161 cataccattt gtaaaatata gaaatcctat cgaagcgata ggatttctat atatcataga
     2221 ttaaagtcat taattttcaa gtgattgcgt tcagttaatt ctagtaaata ggtgtgaagg
     2281 aaaacgatat caggtttcgt ttgaattgct tcattttcta gtatattttg gtacgcatct
     2341 ttttattttg ctcgctaaag tagttgtgag aatgtcaacg aaacgctgta ttattcattg
     2401 tttacactaa gtttacagga acttcaacct ctcgtaaacc ttggtcagtt aaagtgactt
     2461 ttccattaaa aaactccaca agtgcagctt taatagtttc tttttcttct ttatcaacat
     2521 aaatcatcgt atcgacttga tctgtaaagt ttgtatccag ctccatgaga tcatgttctt
     2581 taaggaagtt actgtactct tggtactgag cataagacat ttgaatagca atgccagcct
     2641 gttcttttat ttcaataata ccaatttctt tgacagctaa ggcgacactg ctggcgtaag
     2701 cacgaattag tcctccagcg cctagtttaa taccaccaaa gtagcgtgtc acgaccacac
     2761 agacattggt gagattgtga ttttctagta ccccaagcat gggaacacca gcagtaccac
     2821 taggctcacc atcatcactt gtacgtttaa tttcactacg ttctccaata ataaaggcag
     2881 agcagttatg tgtcgctttg tagtgttctt ttttgatggc agtaatgaag tcacgagcct
     2941 cttcttcgct ataaacacgc ttggcatggc agataaagcg agattttttg atttcttctt
     3001 ggacttggcc gtcctcttta attgtcctaa attccatgat ttaattgtac taaaaaatca
     3061 tctaaagtgc tagtttttac gaataaagaa gtatgaaagt aaatttagat tatctcggtc
     3121 gtttatttac tgagaatgaa ttaacagaag aagaacgtca gttggcggag aaacttccag
     3181 caatgagaaa ggagaagggg aaacttttct gtcaacgttg taatagtact attctagaag
     3241 aatggtattt gcccatcggt gcttactatt gtcgagagtg cttgctgatg aagcgagtca
     3301 gaagtgatca aactttatac tattttccgc aggaggattt tccgaagcaa gatgttctca
     3361 aatggcgcgg ccaattaact ccttttcaag agaaggtgtc agagggactg cttcaagcag
     3421 tagacaagca aaagccaacc ttagttcatg cggtaacagg agctggaaag acagaaatga
     3481 tttatcaagt agtggctaaa gtgatcaatg cgggtggtgc agtgtgtttg gctagtcctc
     3541 gcatagatgt ttgtttggag ctgtacaagc gcctgcaaca ggatttttct tgcgggatag
     3601 ctttgctaca tggagaatcg gaaccttatt ttcgaacacc actagttgtt gcaacaaccc
     3661 atcagttatt gaagttttat caagcttttg atttgctgat agtggatgaa gtagatgctt
     3721 ttccttatgt tgataatccc acgctttacc atgctgtcaa gaatagtgta aaggagaatg
     3781 gattgagaat ctttttaaca gcgacttcga ccaatgagtt agataaaaag gtccgtttag
     3841 gagaactaaa aagactgaat ttaccgagac ggtttcatgg aaatccgttg attattccaa
     3901 aaccaatttg gttatcggat tttaatcgct acttagacaa gaatcgtttg tcaccaaagt
     3961 taaagtccta tattgagaag cagagaaaga cagcttatcc gttactcatt tttgcttcag
     4021 aaattaagaa aggggagcag ttagaagaaa tcttacagga gcaatttcca aatgagaaaa
     4081 ttggctttgt atcttctgta acagaggatc gattagagca agtacaagct tttcgagatg
     4141 gagaactgac aatacttatc agtacgacaa tcttggagcg tggagttacc ttcccttgtg
     4201 tggatgtttt cgtagtagaa gccaatcatc gtttgtttac caagtctagt ttgattcaga
     4261 ttggtggacg agttggacga agcatggata gaccgacagg agatttgctt ttcttccatg
     4321 atgggttaaa tgcttcaatc aagaaggcga ttaaggaaat tcagatgatg aataaggagg
     4381 ctggtctatg aagtgcttgt tatgtgggca gactatgaag actgttttaa cttttagtag
     4441 tctcttactt ctgaggaatg atgactcttg tctttgttca gactgtgatt ctacttttga
     4501 aagaattggg gaagagaact gtccaaattg tatgaaaaca gagttgtcaa caaagtgtca
     4561 agattgtcaa ttttggtgta aagaaggagt tggagtcagt catagagcga tttttactta
     4621 caatcaagct atgaaggatt ttttcagtcg gtataagttt gatggagact tcctgttaag
     4681 aaaagttttc gcttcatttt taagtgagga gttgaaaaag tacaaagagt atcaatttgt
     4741 tgtaattccc ctaagtcctg atagatatgc taatagagga tttaatcagg ttgagggctt
     4801 ggtagaggca gcaggctttg agtatctgga tttattagag aaaagagaag agagagccag
     4861 ttcttctaaa aatcgttcag agcgcttggg gacagaactt cctttcttta ttaaaagtgg
     4921 agtcactatt cctaaaaaaa tcctacttat agatgatatc tatactacag gagcaactat
     4981 aaatcgtgtt aagaaactgt tggaagaagc tggtgctaag gatgtaaaaa cattttccct
     5041 tgtaagatga ggaaaaaatt tgcaaaaata gaatgaaagc gttataataa aatcataaaa
     5101 acaaaaatgt ttagaaagaa ggtactcata tgattaaata tagtatccgt ggtgaaaacc
     5161 tagaagtaac agaagcaatt cgtgattatg tagtttctaa actcgaaaag atcgaaaagt
     5221 acttccaacc agaacaagag ttggatgccc gaattaactt aaaagtttat cgtgaaaaaa
     5281 cggctaaagt ggaagtaacg attccgcttg gatctattac tctccgcgca gaagatgtat
     5341 ctcaagatat gtatggttca attgaccttg taactgataa aattgaacgt cagattcgta
     5401 aaaataaaac aaaaatcgag cgtaaaaata aaaataaggt agcaactggt caattattta
     5461 cagatgcttt ggtggaagat tcaaatgttg tccagtctaa agttgttcgt tcaaaacaaa
     5521 ttgatttaaa accaatggat ttggaagaag caattctaca aatggattta ttggggcatg
     5581 atttctttat ctatgtggat gttgaagatc agacaaccaa tgtgatttat cgtcgtgagg
     5641 atggcgaaat tggtttgtta gaggttaaag aatcttaatt tcaatatgtg taaaggtagg
     5701 tttactgaat tgtaaactac ctttttctta taattgatag aattactgat tacactttta
     5761 aaaagtcgct ttttgagggg tattatggta taatgggtgc caagaggttt tgaatgaaaa
     5821 aattttatgt aagtccaatt tttcctattc tagtaggatt gattgcgttt ggagtcttat
     5881 ccactttcat tatttttgtt aataataatc tgttgacggt tttaattttg tttctttttg
     5941 taggaggcta tgttttttta tttaagaaac tgagagtgca ttatacaagg agtgatgtag
     6001 aacagataca gtatgtaaac caccaagcgg aagaaagttt gacatctcta ttggaacaaa
     6061 tgcctgtagg tgttatgaaa ttgaatttat cttctggaga ggttgagtgg tttaatccct
     6121 atgctgaatt gattttgacc aaggaagatg gtgattttga tttagaagct gttcaaacga
     6181 ttatcaaggc ttcagtagga aatccgtcta cttatgccaa gcttggtgag aagcgttatg
     6241 ctgttcatat ggatgcttct tccggtgttt tgtattttgt agatgtatcc agggaacaag
     6301 ccataacaga tgaattggta acaagtcgac cagtgattgg gattgtctct gtggataatt
     6361 atgatgattt ggaggatgca acttctgagt cagatattag tcaaatcaat agttttgtag
     6421 ctaattttat atcagagttt tcagaaaaat acatgatgtt ttctcgtcgg gtaagtatgg
     6481 atcgatttta tctatttact gactacacgg tgcttgaggg cttgatgaat gataaatttt
     6541 ctgttattga tgctttcaga gaagagtcga aacagagaca gttgcccttg accttaagta
     6601 tgggattttc ttatggcgat ggaaatcatg atgagatagg gaaagttgct ttgctcaatt
     6661 tgaacttggc tgaagtacgt ggtggcgacc aggtggttgt taaggaaaac gacgaaacga
     6721 aaaatccagt ttattttggt ggtgggtctg ctgcttcaat caagcgtaca cggactcgta
     6781 cgcgcgctat gatgacagct atttcagata agattcggag tgtagatcat gtttttgtag
     6841 tcggtcacaa aaatttagac atggatgctt tgggctctgc tgtaggtatg cagttgttcg
     6901 ccagcaatgt gattgaaaat agctatgctc tttatgatga agaacaaatg tctccagata
     6961 ttgaacgagc tgtttcattc atagaaaaag aaggagttac gaagttgttg tctgttaagg
     7021 atgcaatggg gatggtgacc aatcgttctt tgttgattct tgtagaccat tcaaagacag
     7081 ccttaacatt atcaaaagaa ttttatgatt tatttaccca aaccattgtt attgaccacc
     7141 atagaaggga tcaggatttt ccagataatg cggttattac ttatatcgaa agtggtgcaa
     7201 gtagtgccag tgagttggta acggaattga ttcagttcca gaattctaag aaaaatcgtt
     7261 tgagtcgtat gcaagcaagt gtcttgatgg ctggtatgat gttggatact aaaaatttca
     7321 cctcgcgagt aactagtcgg acatttgatg ttgctagcta tctcagaacg cgcggaagtg
     7381 atagtattgc tatccaggaa atcgctgcga cagattttga agaatatcgt gaggtcaatg
     7441 aacttatttt acaggggcgt aaattaggtt cagatgtact aatagcagag gctaaggaca
     7501 cgaaatgcta tgatacagtt gttattagta aggcagcaga tgccatgtta gccatgtcag
     7561 gtattgaagc gagttttgtt cttgcgaaga atacacaagg atttatctct atctcagctc
     7621 gaagtcgtag taaactgaat gtacaacgga ttatggaaga gttaggcggt ggaggccact
     7681 ttaatttggc agcagctcaa attaaagatg taaccttgtc agaagcaggt gaaaaactga
     7741 cagaaattgt attaaatgaa ataaaggaaa aggagaaaga agaatgaaag taatcttttt
     7801 agcagatgtt aaaggaaaag gtaaaaaagg cgaaattaag gaagtaccaa cagggtatgc
     7861 gcaaaacttt cttatcaaaa agaatctagc caaagaagcg actgctcaag ctgtaggtga
     7921 acttcgtggt aaacaaaaat cggaagaaaa agctcacgct gagatgattg cagaagggaa
     7981 agcaattaaa gcacaacttg aagcagaaga aactgttgta gaatttgttg aaaaagttgg
     8041 tccagatggt cgtacctttg gttctattac caataagaag attgcagaag aattacaaaa
     8101 gcaatttgga attaagattg ataaacgtca tattcaagta caagctccga ttcgagcggt
     8161 tggtttgatt gatgtgccag tgaaaatcta tcaagatatc acaagtgtaa tcaatcttcg
     8221 tgtgaaagaa ggataagttt acaccttctt gacaagattg taaaaggaag ggaagtctga
     8281 tggcagaagt agaagagtta cgagtacaac ctcaagatat cttagctgag caatccgttt
     8341 taggggctat ctttattgat gagagtaaac ttgtttttgt gcgagaatac attgagtctc
     8401 gggacttttt taagtatgcc catcgtttga ttttccaagc catggtcgat ttatccgatc
     8461 gtggtgatgc catagatgca acaacggttc gtactatcct tgataatcaa ggtgatttac
     8521 agaatattgg tggcttgtct tacttggttg agattgtcaa ttctgtgcca acttctgcta
     8581 atgcggagta ttatgctaag attgttgcag aaaaagcaat gctacgtcgt ttaattgcca
     8641 agttgacaga gtctgtcaac caagcttacg aagcgtcaca accagctgat gaaattattg
     8701 ctcaggcaga aaaagggctg attgatgtca gtgaaaatgc aaatcgaagc gggtttaaga
     8761 acattcgaga tgtgttgaat ctcaactttg gaaatctgga agctcgctcg caacaaacga
     8821 ccgatattac aggtattgcg acaggttatc gtgatttgga tcatatgaca acaggacttc
     8881 atgaggagga gttgattatc ttagcagctc gtccagcagt tggtaagaca gcatttgcct
     8941 tgaatatcgc tcagaatatt gggactaagt tggacaaaac ggttgctatt ttttcactcg
     9001 aaatgggtgc ggaaagcttg gtagaccgta tgttagctgc agaaggcttg gtggagtcac
     9061 attctatccg tacagggcaa ttgacagatg aggagtggca aaaatatact attgctcagg
     9121 gtaatctagc taacgccagt atctatatcg atgatacgcc aggtattcgg attacagaga
     9181 ttcgttctcg ttctcgtaaa ttggctcaag aaactggaaa tcttggtttg attttgatag
     9241 actatttgca acttatcacg ggaactggtc gagaaaatcg tcaacaagaa gtttctgaaa
     9301 tttctcgtca gttgaaaata ctagccaagg aattgaaggt tccagtaatc gctctgagtc
     9361 agctttctcg tggtgtagaa caacgtcagg acaagagacc ggtcttgtct gatattcgtg
     9421 aatctgggtc tattgagcag gacgctgata tcgtagcttt tctctatcgc gatgactact
     9481 atgaacgtgg tggtgaagaa gaggagggta tcccaaataa taaggtggaa gttattatcg
     9541 agaaaaaccg tagtggagct cgtggaacag tggaattgat tttccaaaaa gaatacaata
     9601 aattttcaag tatctcaaag agggaggcat aagatgtcag atgcatttac agatgtagcc
     9661 aagatgaaaa aaatcaaaga agaaatcaag gcacatgagg gacaagtcgt agaaatgact
     9721 ttggagaatg gtcgtaagcg ccaaaaaaat agattgggta agctaattga agtttatcca
     9781 tccctattta ttgtggagtt tggggatgtg gaaggagata aacaagttaa tgtttacgtt
     9841 gaatccttta cttactcaga tattcttaca gaaaagaatt tgattcatta tcttgactaa
     9901 agtgagaaat tttctcactt tttctttttt ctccgaataa tttaggtgaa ggcaatcatc
     9961 gctttatatt attttttaag gaggaagaat gaaaatttta ccgtttatag caagaggaac
    10021 aagttattac ttgaagatgt cagttaaaaa gcttgttcct tttttagtag taggattgat
    10081 gctagcagct ggtgatagtg tctatgccta ttccggagga aatggatcga ttgcgcgtgg
    10141 ggatgattat cctgcttatt ataaaaatgg gagtcaggag attgatcagt ggcgcatgta
    10201 ttctcgtcag tgtacttctt ttgtagcctt tcgtttgagt aatgtcaatg gttttgaaat
    10261 tccggcagct tatggaaatg cgaatgaatg gggacatcgt gctcgtcggg aaggttatcg
    10321 tgtagataat acaccgacga ttggttccat tacttggtct actgcaggaa cttatggtca
    10381 tgttgcctgg gtgtcaaatg taatgggaga tcagattgag attgaggaat ataactatgg
    10441 ttatacagaa tcctataata aacgaattat aaaagcaaac acgatgacag gatttattca
    10501 ttttaaagat ttggatggtg gcagtgttgg gaatagtcaa tcctcaactt caacaggcgg
    10561 aactcattat tttaagacca agtctgctat taaaactgaa cccctagtta gtgcaactgt
    10621 gattgattac tattatcctg gagagaaggt tcattatgat caaattctcg aaaaagacgg
    10681 ctacaagtgg ttgagttata ctgcctataa tggaagctat cgttatgttc aattggaggc
    10741 tgtgaataaa aatcctctag gtaattctgt tctttcttca acaggtggaa ctcattattt
    10801 taagaccaag tctgctatca aaactgaacc cctagttagt gcaactgtga ttgattacta
    10861 ttatcctggg gagaaggttc attatgatca gatacttgaa aaagacggct acaagtggtt
    10921 gagttatacg gcttataacg gaagtcgtcg ctatatacag ctagagggag tgacttcttc
    10981 acaaaattat cagaatcaat caggaaatat ctctagctat ggatccaata atagttcaac
    11041 tgtcggttgg aagaaaataa atggtagttg gtatcatttc aaatcaaatg gttctaaatc
    11101 aacaggatgg ctgaaagatg gttctagctg gtattatttg aaattatctg gtgaaatgca
    11161 gacaggatgg ttaaaggaga atggctcgtg gtattatctg ggtagttcag gggcaatgaa
    11221 aacaggctgg taccaggtct ctggtaagtg gtattattct tactcttcag gcgccttagc
    11281 tgttaatacg acggtggatg gctacagagt aaacagtgat ggagaacgag tatagaaaat
    11341 tggagtagga gaaatttcct gctcttttct gtaagcagtt tccttgacat ttttcttatt
    11401 ttgcgctatc atatatacat ataatatatg ggagtctgtg tacagtctga gaggaagtgt
    11461 taaacttcga ccgcacctga tctgggtaat gccagcggag ggaacgatac ttagtctaat
    11521 tttgcacctt ttccatgtat ggtaaaggtt tttctttttt ttaaaaggaa aacgagaaga
    11581 ggaggttctt atgaaagcaa gcattgcctt gcaagtttta cccctagtac aggggattga
    11641 tcggatagct gttattgatc aggtcattgc ttatctgcaa actcaagaag tgccgatggt
    11701 agtgacacca tttgaaacgg tcttggaagg ggagtttgat gagcttatgc gcattctaaa
    11761 agaagcgctg gaagtggcag ggcaggaggc agacaatgtc tttgccaatg tcaaaataaa
    11821 tgtaggagag attttaagta ttgatgagaa acttgagaag tatactgaga cgacacatta
    11881 gtctattggg ctttctcgga gtcttgtcaa tctggcagtt agcaggtttt cttaaactgc
    11941 tccccaagtt tatcctgccg acacctcttg aaattctcca gccctttgtt cgtgacagag
    12001 aatttctctg gcaccatagc tgggcgacct tgagagtggc tttactgggg ctgattttgg
    12061 gagttttgat tgcctgtctt atggctgtac tcatggatag tttgacttgg ctcaatgacc
    12121 tgatttaccc tatgatggtg gtcattcaga ccattccgac cattgccata gctcctatcc
    12181 tggtcttgtg gctaggttat gggattttgc ccaagattgt cttgattatc ttaacgacaa
    12241 cctttcccat catcgtcagc attttggacg gttttaggca ttgcgacaag gatatgctga
    12301 ctttgtttag tctgatgcgg gccaagcctt ggcaaatcct gtggcatttt aaaattccag
    12361 tcagcctgcc ctacttttat gctggtctga gggtcagtgt ctcctacgct tttatcacaa
    12421 cagtggtatc tgagtggttg ggaggctttg aggggcttgg tgtttatatg attcagtcca
    12481 agaaattgtt tcagtatgat accatgttcg ctattattat tctggtatcg attatcagcc
    12541 ttttgggtat gaagttggtc gatattagtg aaaaatatgt tattaaatgg aaacgttcgt
    12601 agaattagaa tgtttctgaa aaagaaaaga ggaaatcaaa atgaagaaaa catggaaagt
    12661 gtttttaacg cttgtaacag ctcttgtagc tgttgtgctt gtggcctgtg gtcaaggaac
    12721 tgcttctaaa gacaacaaag aggcagaact taagaaggtt gactttatcc tagactggac
    12781 accaaatacc aaccacacag ggctttatgt tgccaaggaa aaaggttatt tcaaagaagc
    12841 tggagtggat gttgatttga aattgccacc agaagaaagt tcttctgact tggttatcaa
    12901 cggaaaggca ccatttgcag tgtatttcca agactacatg gctaagaaat tggaaaaagg
    12961 agcaggaatc actgccgttg cagctattgt tgaacacaat acatcaggaa tcatctctcg
    13021 taaatctgat aatgtaagca gtccaaaaga cttggttggt aagaaatatg ggacatggaa
    13081 tgacccaact gaacttgcta tgttgaaaac cttggtagaa tctcaaggtg gagactttga
    13141 gaaggttgaa aaagtaccaa ataacgactc aaactcaatc acaccgattg ccaatggcgt
    13201 ctttgatact gcttggattt actacggttg ggatggtatc cttgctaaat ctcaaggtgt
    13261 agatgctaac ttcatgtact tgaaagacta tgtcaaggag tttgactact attcaccagt
    13321 tatcatcgca aataacgact atctgaaaga taacaaagaa gaagctcgca aagtcatcca
    13381 agccatcaaa aaaggctacc aatatgccat ggaacatcca gaagaagctg cagatattct
    13441 catcaagaat gcacctgaac tcaaggaaaa acgtgacttt gtcatcgaat ctcaaaaata
    13501 cttgtcaaaa gaatacgcaa gcgacaagga aaaatggggt caatttgacg cagctcgctg
    13561 gaatgctttc tacaaatggg ataaagaaaa tggtatcctt aaagaagact tgacagacaa
    13621 aggcttcacc aacgaatttg tgaaataatg acagaaatta gactagagca cgtcagttat
    13681 gcctatggtc aggagaggat tttagaggat atcaacctac aggtgacttc aggcgaagtg
    13741 gtttccatcc taggcccaag tggtgttgga aagaccaccc tctttaatct aatcgctggg
    13801 attttagaag ttcagtcagg gagaattgtc cttgatggtg aagaaaatcc caaggggcgc
    13861 gtgagttata tgttgcaaaa ggatctgctc ttggagcaca agacggtgct tggaaatatc
    13921 attctgcccc tcttgattca aaaggtggat aaggcagaag ctatttcccg agcggataaa
    13981 attcttgcga ccttccagct gacagctgta agagacaagt atcctcatga acttagcggt
    14041 gggatgcgcc agcgtgtagc cttactccgg acctaccttt ttgggcacaa gctctttctc
    14101 ttagatgagg cctttagcgc cttggatgag atgacaaaga tggaactcca cgcttggtac
    14161 cttgagattc acaagcagtt gcagctaaca accttgatta ttactcacag tatcgaggag
    14221 gccctcaatc tcagtgaccg tatctatatc ttgaaaaatc gccctgggca gattgtttca
    14281 gaaattaaac tagattggtc tgaagatgag gacaaggaag tccaaaagat tgcctacaaa
    14341 cgtcaaatct tggcagaatt aggcttagat aagtagaaaa atagggagtt ggtgaagatt
    14401 atcctttacc agcgcccttt ttcttttaaa aatgagaaaa tttcggtata atagtcaaac
    14461 aaggtcaagg tctaaagaga gaggtgggtt tgttatgaga tttaaaaata catcggatca
    14521 tattgaggcc tacatcaagg cgattttaga tcaatctggt atcgtggagt tgcaacggag
    14581 tcagttggca gatacctttc aggttgttcc tagtcagatt aactacgtga tcaagacacg
    14641 ctttacggaa agtagaggct acttggttga aagtaagcgt ggtggcggag gctacattcg
    14701 tataggacgg attgagtttt ctagtcatca tgaaatgctc cgggagctgc tttactcgat
    14761 tggtgagcga gtcagtcaag aaatttatga ggatattctc cagcttttgg ttgagcagga
    14821 attgatgacc aagcaggaga tgaatttgct agaatcagta gctttggatc gcgttttagg
    14881 agaagaagct ccagttgttc gagcaaacat gctacgtcag attatacaag aggtagatag
    14941 aaaagggaag taagatgaac tattcaaaag cattgaatga atgtatcgaa agtgcctaca
    15001 tggttgctgg acattttgga gctcgttatc tagagtcttg gcacttgttg attgccatgt
    15061 ctaatcatag ttatagtgta gcaggggcaa ctttaaatga ttatccgtat gagatggacc
    15121 gtttagaaga ggtggctttg gaactgactg aaacggacta tagccaggat gaaaccttta
    15181 cggaattgcc gttctcccgt cgtttgcagg ttctttttga cgaagcagag tatgtagcgt
    15241 cagtggtcca tgctaaggtg ctagggacag agcacgtcct ctatgcgatt ttgcatgatg
    15301 gcaatgcctt ggcaactcgt atcttggaga gggctggttt ttcttatgaa gacaagaaag
    15361 atcaggtcaa gattgctacc cttcgtcgaa atttagaaga acgggcagga tggactcgtg
    15421 aagatctcaa ggctttacgc caacgccatc gtacagtagc tgacaggcaa aattctatgg
    15481 ccaatatgat gggcatgccg cagactccta gtggtggtct cgaggattat acgcatgatt
    15541 tgacagagca agcgcgttct ggcaagttag aaccagtcat cggtcgggac aaggaaatct
    15601 cacgtatgat tcaaatcttg agccggaaga ctaagaacaa ccctgtcttg gttggggatg
    15661 ctggtgtcgg gaaaacagct ctggcgcttg gtcttgccca gcgtattgct agtggtgacg
    15721 tgcctgcgga aatggctaag atgcgcgtgt tagaacttga tttgatgaat gtcgttgcag
    15781 ggacacgctt ccgtggtgac tttgaagaac gcatgaataa tatcatcaag gatattgaag
    15841 aagatggcca agtcatcctc tttatcgatg aactccacac catcatgggt tctggtagcg
    15901 gaattgattc gactctggat gcggccaata tcttgaaacc agccttggcg cgtggaactt
    15961 tgagaacggt tggtgccacc actcaggaag aatatcaaaa acatatcgaa aaagatgcgg
    16021 cactttctcg tcgtttcgct aaagtgacga ttgaagaacc aagtgtggca gatagtatga
    16081 ctattttaca aggtttgaag gcgacttatg agaaacatca ccgtgtacaa atcacagatg
    16141 aagcggttga aacagcggtt aagatggctc atcgttattt aaccagtcgt cacttgccag
    16201 actctgctat cgacctcttg gacgaagcag cagcaacagt gcaaaataag gcaaagcatg
    16261 taaaagcaga cgattcagat ttgagtccag ctgacaaggc cctgatggat ggcaagtgga
    16321 aacaggcagc ccagctaatc gcaaaagaag aggaagtacc tgtctacaaa gacttggtga
    16381 cagagtctga tattttgacc accttgagtc gcttgtcagg aatcccagtt caaaagctga
    16441 ctcagactga cgctaagaaa tatctaaatc ttgaagcaga actccataaa cgggttatcg
    16501 gtcaagatca agctgtttca agtattagtc gtgccattcg ccgtaatcag tcaggaattc
    16561 gcagtcacaa gcgtccgatc ggttccttta tgttcctagg acccacaggt gtcggtaaga
    16621 ccgagttggc caaggctttg gcagaagttc tctttgatga cgaatcagcc cttatccgct
    16681 ttgatatgag tgagtatatg gagaaattcg cagccagccg tctaaatgga gctcctccag
    16741 gctatgtggg ttacgaagaa ggtggggagt tgacagagaa ggttcgcaat aaaccctatt
    16801 ccgttctcct ctttgatgag gtagagaagg cccacccaga tatctttaat gttctcttgc
    16861 aggttctgga tgacggtgtc ttgacagata gcaagggacg caaggtcgat ttttcaaata
    16921 ccattatcat tatgacatcg aatctaggtg cgactgccct tcgtgatgat aagactgttg
    16981 gttttggggc taaggatatt cgttttgacc aggaaaatat ggaaaaacgc atgtttgaag
    17041 aactgaaaaa agcttataga ccggaattca tcaaccgcat tgatgagaag gtggtcttcc
    17101 atagcctatc tagtgaccat atgcaggaag tggtgaagat tatggtcaag cctttagtgg
    17161 caagtttggc tgaaaaaggc attgacttga aattacaagc ttcagctctg aaattgttag
    17221 caaatcaagg atatgaccca gagatgggag ctcgcccact tcgcagaacc ttgcaaacag
    17281 aagtggaaga caagttggca gaacttcttc ttaagggaga tttagtggca ggcaacacac
    17341 ttaagattgg tgtcaaagca ggccagttaa aatttgatat tgcataaaag aataaaagta
    17401 tcagcatctg accataagtc acagtggagt gaaactcaat gaaaatcaaa gagcaaacta
    17461 ggcagctagc cgcaggttgc tcaaaacact gttttgaggt tgcagataga gctgacgtgg
    17521 tttgaagaga ttttcgaaga gtataagctg caagatgaat gattttcttg tattgacgtt
    17581 gttgttgaca aaaagtagcg gataaatgaa atccattcca ttatcataga tgataggctg
    17641 gtaggaaatt ttcaaatagc atacaggaaa tagatgtatg gagttctggt agtagaaagg
    17701 gagagagatg aacattttag ttgcagatga cgaggaaatg attagagaag gaattgcagc
    17761 atttctgaca gaagagggtt atcatgtcat tatggctaag gatggacaag aggtcttgga
    17821 aaaatttcaa gatctcccta tccatctcat ggtattggat ttaatgatgc ctaggaagag
    17881 tggttttgaa gtgttaaaag aaatcaatca aaagcacgat attcctgtca tcgtcttgag
    17941 tgctctggga gatgaaacta ctcagtcaca ggtatttgat ctctatgctg atgatcatgt
    18001 gacaaaacct ttttctttgg tactgcttgt caagcgtatt aaggcgctta tcagacgtta
    18061 ctacgtcata gaggatattt ggcgatatca ggatgtaaca gtggatttta cctcttacaa
    18121 agcacattat aaaaatgaag aaattgatct caaaccaaag gaattactgg tactaaagtg
    18181 tttgattcag cataaaaatc aagttttaag tagagagcag atattggaag aaatttcaaa
    18241 agatgtagct gatttacctt gtgatagggt cgttgatgtc tatattcgta ctcttcgcaa
    18301 aaaattagct ttagattgta tcgtgactgt gaaaaatgtt gggtataaga ttagtttatg
    18361 ataaaaaatc ctaaattatt aaccaagtcc tttttaagaa gttttgcaat tctaggtggt
    18421 gttggtctag tcattcatat agctatttat ttgacctttc ctttttatta tattcaactg
    18481 gagggggaaa agtttaatga gagcgcaaga gtgtttacgg agtatttaaa gactaagaca
    18541 tctgatgaaa ttccaagctt actccagtct tattcaaagt ccttgaccat atctgctcac
    18601 cttaaaagag atattgtaga taagcggctc cctcttgtgc atgacttgga tattaaagat
    18661 ggaaagctat caaattatat cgtgatgtta gatatgtctg ttagtacagc agatggtaaa
    18721 caggtaacag tgcaatttgt tcacggggtg gatgtctaca aagaagcaaa gaatattttg
    18781 cttttgtatc tcccatatac atttttggtt acaattgctt tttcctttgt tttttcttat
    18841 ttttatacta aacgcttgct caatcctctt ttttacattt cagaagtgac tagtaaaatg
    18901 caagatttgg atgacaatat tcgttttgat gaaagtagga aagatgaagt tggtgaagtt
    18961 ggaaaacaga ttaatggtat gtatgagcac ttgttgaagg ttatttatga gttggaaagt
    19021 cgtaatgagc aaattgtaaa attgcaaaat caaaaggttt cctttgtccg cggagcatca
    19081 catgagttga aaaccccttt agccagtctt agaattatcc tagagaatat gcagcataat
    19141 attggagatt acaaagatca tccaaaatat attgcaaaga gtataaataa gattgaccag
    19201 atgagccact tattagaaga agtactggag tcttctaaat tccaagagtg gacagagtgt
    19261 cgtgagacct tgactgttaa gccagtttta gtagatattt tatcacgtta tcaagaatta
    19321 gctcattcaa taggtgttac aattgaaaat caattgacag atgctaccag ggtcgtcatg
    19381 agtcttaggg cattggataa ggttttgaca aacctgatta gtaatgcaat taaatattca
    19441 gataaaaatg ggcgtgtaat catatccgag caagatggct atctctctat caaaaataca
    19501 tgtgcgcctc taagtgacca agaactagaa catttatttg atatattcta tcattctcaa
    19561 atcgtgacag ataaggatga aagttccggt ttgggtcttt acattgtgag taatatttta
    19621 gaaagctatc aaatggacta tagttttctc ccttatgaac acggtatgga atttaagatt
    19681 agcttgtaga cagattagtt ttttattaaa gttcacatag ggttaacata agtgtattat
    19741 tctttatata gataaaaata tagataaaag aaaggatact aatatggtat tagcgattat
    19801 tttagtaaca ttccttattc gattgatttt tttaaagcgt tcgatagaga atgagaaacg
    19861 aatccttagc aatggcggga aagaatttgg agttgagaat acaaaacgat taactatggc
    19921 tcatattgtt ttttatctct cttgcttggt tgaggcaatg gtgcacaaga caatttttga
    19981 tagcatgggc atggttggtt tagtcttgct tattttttct atgctgatgt taatgttggt
    20041 gattcacttg ttgggagata tttggacagt gaagcttatg cttgtcaata atcacaaata
    20101 tgtagatcat atcttgttta ggacagtaaa acatcctaat tactttttaa atattcttcc
    20161 tgagttgatt ggcttgacct tgttgagtca tgcttatgtg acttttgttt tagtttttcc
    20221 agtttatgca gttattttgt atcgacgaat agctgaagag gaaaagctat tacatgaagt
    20281 tataatccca aatggaagaa tgaaaggtta aaaataaaat acccaattta atatacagtt
    20341 catattggaa gggtatactg aagatgaata aaatattata ggatatcgat atgtttaaat
    20401 caaattatga aagaaaaatg tgctattcta ttcgaaaatt tagtatagga gtagctagtg
    20461 tagctgttgc cagtcttgtt atgggaagtg tggttcatgc gacagagaac gagggaacta
    20521 cccaagcacc cacttcttct aataggggaa atgaaagtca ggcagaacaa cgtagagaac
    20581 tcgatttaga acgagataag gtaaagaaag aggtcaggga atataaagaa aaaaaagtga
    20641 aagagctcta ttcaaaatca actaaaagtc gacataagaa gactgtagat atagttaaca
    20701 agttgcaaaa cattaataac gagtatttga ataaaataat tcaatcaacc tcaacatacg
    20761 aagaactaca gaaactgatg atggagagtc aatcagaagt agataaagct gtgtctgaat
    20821 ttgaaaagga cttatcttct tcgtcaagtt caggctcttc cacggaaccg gaagcttcag
    20881 atacagcgaa gccaaacaag ccgacagaac tagaaaaaaa ggtagcagaa gctcagcaga
    20941 aggttgaaga agctgagaaa aaagccaagg atcaaaaaga agaagattac cgtaactacc
    21001 caaccattac ttacaaaacg cttgaacttg aaattgctga gttcgatgtg aaagttaaag
    21061 aagcggagct tgaactatta aaagtgaaag ctaaggaatc tcgagacgag aaaaaaatta
    21121 agcaagcaga agcggaagtt gagagtaaac aagctgaggc tacaaggtta aaaaaaatca
    21181 agacagatcg taaaaaagca gaagaagaag ctaagttgaa ggaagctgtt gaaaagaatg
    21241 cagcgacttc agagcaaggt aaaccaaaga ggcgggtaaa acgaggagct cttggagagc
    21301 aagcaacacc tgataaaaaa gattattttg aaaaagactt ccgtccagct ttcaataaaa
    21361 accagcagat ggtagccatt caagaatcct tgaacaaact agatgatgaa acaaaaactg
    21421 ttccagatgg ggctaaactc acaggagaag ctggaaatgc ctataatgag gtcagagatt
    21481 atgcaataaa agttgtttct gaaaacaaga aacttctatc acagacagca gtgacaatgg
    21541 atgaactggc aatgcaatta accaaattga acgatgccat gtctaaattg aaagaagcta
    21601 aagcgaaatt ggtaccagag gttaaaccgc agccggaaaa tccagagcat caaaaaccaa
    21661 caactccagc tccggatacc aaaccaatcc ctcaaccaga gggtaagaaa ccaagcgtac
    21721 cagatattaa tcaggaaaaa gaaaaagcta agcttgctgt agcaacctac atgagcaaga
    21781 ttttagatga tatacaaaaa catcatctgc agaaagaaaa acatcgtcag attgttgctc
    21841 ttattaagga gcttgatgag tttaaaaagc aagctctttc tgaaattgat aatgtaaata
    21901 ccaaagtaga aattgaaaat acagtccaca agatatttgc agacatggat gcagttgtga
    21961 ctaaattcaa aaaaggctta actcaggaca caccaaaaga accagataa
//
LOCUS       DBERPV010000033        21855 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.33, whole genome shotgun sequence.
ACCESSION   DBERPV010000033 DBERPV010000000
VERSION     DBERPV010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 21855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21855
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.33"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..82
                     /gene="tnpB"
                     /locus_tag="ACL8C7_001605"
     CDS             <1..82
                     /gene="tnpB"
                     /locus_tag="ACL8C7_001605"
                     /inference="COORDINATES: protein motif:HMM:NF017528.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGS1395763.1"
                     /translation="DRFKALYWDGQGFWLLYKRFENGKLT"
     gene            complement(898..2625)
                     /gene="ezrA"
                     /locus_tag="ACL8C7_001606"
     CDS             complement(898..2625)
                     /gene="ezrA"
                     /locus_tag="ACL8C7_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HGS1395764.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2707..4653)
                     /gene="gyrB"
                     /locus_tag="ACL8C7_001607"
     CDS             complement(2707..4653)
                     /gene="gyrB"
                     /locus_tag="ACL8C7_001607"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HGS1395765.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEIVGDTDKTGTTVHFTPDPKIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4668..5231)
                     /locus_tag="ACL8C7_001608"
     CDS             complement(4668..5231)
                     /locus_tag="ACL8C7_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGS1395766.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(5316..5870)
                     /locus_tag="ACL8C7_001609"
     CDS             complement(5316..5870)
                     /locus_tag="ACL8C7_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1 family glyoxalase III"
                     /protein_id="HGS1395767.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5881..7104)
                     /locus_tag="ACL8C7_001610"
     CDS             complement(5881..7104)
                     /locus_tag="ACL8C7_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGS1395768.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(7141..9591)
                     /locus_tag="ACL8C7_001611"
     CDS             complement(7141..9591)
                     /locus_tag="ACL8C7_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HGS1395769.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLRKKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTEASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEDFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVGHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIIGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9791..10720)
                     /locus_tag="ACL8C7_001612"
     CDS             complement(9791..10720)
                     /locus_tag="ACL8C7_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HGS1395770.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     AQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVR"
     gene            10860..11147
                     /locus_tag="ACL8C7_001613"
     CDS             10860..11147
                     /locus_tag="ACL8C7_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HGS1395771.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(11181..12515)
                     /gene="ciaH"
                     /locus_tag="ACL8C7_001614"
     CDS             complement(11181..12515)
                     /gene="ciaH"
                     /locus_tag="ACL8C7_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HGS1395772.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12505..13179)
                     /gene="ciaR"
                     /locus_tag="ACL8C7_001615"
     CDS             complement(12505..13179)
                     /gene="ciaR"
                     /locus_tag="ACL8C7_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HGS1395773.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(13288..15834)
                     /locus_tag="ACL8C7_001616"
     CDS             complement(13288..15834)
                     /locus_tag="ACL8C7_001616"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HGS1395774.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15957..16361)
                     /locus_tag="ACL8C7_001617"
     CDS             complement(15957..16361)
                     /locus_tag="ACL8C7_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000267274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HGS1395775.1"
                     /translation="MNPLIGDEIDAWAFGVEPDLLADLVFKGEKTATASAYDLYVLED
                     EPLPQVGTFDVILDSQNQAVCVVEITKVSVELFNQVSAQHAFKEGEGDKSLAYWRQVH
                     EDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(16372..17241)
                     /locus_tag="ACL8C7_001618"
     CDS             complement(16372..17241)
                     /locus_tag="ACL8C7_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative PEP-binding protein"
                     /protein_id="HGS1395776.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLDTICSFYLDKEVWYRFSELTNTEANCLAGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAESHVVTEVYQTNPNLSLIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(17283..18011)
                     /locus_tag="ACL8C7_001619"
     CDS             complement(17283..18011)
                     /locus_tag="ACL8C7_001619"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1395777.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(18019..18498)
                     /locus_tag="ACL8C7_001620"
     CDS             complement(18019..18498)
                     /locus_tag="ACL8C7_001620"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGS1395778.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKARGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELTNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVK"
     gene            complement(18509..19207)
                     /locus_tag="ACL8C7_001621"
     CDS             complement(18509..19207)
                     /locus_tag="ACL8C7_001621"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HGS1395779.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(19200..19436)
                     /locus_tag="ACL8C7_001622"
     CDS             complement(19200..19436)
                     /locus_tag="ACL8C7_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018367459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HGS1395780.1"
                     /translation="MTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTIEQNGLALEMT
                     PYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(19534..20460)
                     /locus_tag="ACL8C7_001623"
     CDS             complement(19534..20460)
                     /locus_tag="ACL8C7_001623"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HGS1395781.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELAETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFNLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSQAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(20535..21350)
                     /locus_tag="ACL8C7_001624"
     CDS             complement(20535..21350)
                     /locus_tag="ACL8C7_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395782.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(21354..21674)
                     /locus_tag="ACL8C7_001625"
     CDS             complement(21354..21674)
                     /locus_tag="ACL8C7_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGS1395783.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
BASE COUNT         6605 a         4764 c         3837 g         6649 t
ORIGIN      
        1 agaccgcttt aaagcccttt actgggatgg tcaaggattt tggctactat ataaacgctt
       61 tgagaacgga aaactgactt gaccaagtac agaaaaggat gtcaaagctc tcacaccaga
      121 acaagtagac tggcttatga agggcttttc tatcactccc caaatatagt ggatttaaac
      181 tagaatagta cacccctact tctaaaacat tgttagaaat cgatttgact gtcctaatcg
      241 atttgtcctg ttcttgtttc attttactat agaacgattt gaaggcgttt atgatattta
      301 gctgtacgag agtcttttaa aagtgttttg atggtttgga tttcttcttt agttgatttc
      361 atattactat tatatagtgc ttttttattt tagtctggta taaatagcga gaaatatcta
      421 tcctatcttc tagaatgtct tccaaacgag aaaactctcg taaacaaaga ggttttagag
      481 gcctatttac cgtagactaa agttgtacaa gaaaagtgca aataagaaat ctccagatta
      541 ggaactatcc gtgagttctc tagtctggag atttttcaat agacttcatt attggacggt
      601 taccaagtta ctcaaagtac agatttgaag ctgcagataa gactgacgaa atcactttaa
      661 tactaaatga aaatcaaaaa gcaaactaag aagctagcct caggctgtac ttgagtacgg
      721 taaggcgacg ctgacgtgat ttgaagagat tttcgaagag tataaaacac tgttttgagg
      781 tggtggataa atcggctggg caaaaactca atctcaggag aaaatgaagt aaatctcccc
      841 acaactatag aaaaagattt gattctgctc ctcacacaat aaaatctttt tcttttatta
      901 aaaacgaatc gtttcacgtg ttttctcata tgaggtaaca aagcgattgg ttacaccagg
      961 ctctgccact tccaatgctt gagaaatctt gtcaaatgaa gcgtgataat caaattcttt
     1021 ttcaaaaata tctaaagctt cgttaaatgc ttcttgaatg cgttcatcaa atgagcgata
     1081 gcggttagaa tattgcaaga gttgctctgt caaagttgca tattgtacaa tattataagt
     1141 ttccgtttct aaagcttcca tatcattcgt tgcaatttca agaactcggg taacagattc
     1201 aatgttaatc attttttgtt ctaactcaac cattaaatcc tcggtattat tgcttgccgt
     1261 aaagaataac ttcaagaaag tttgtggaat acctggcaga ttgcgttttt ccatgtatcg
     1321 cttgatagta tggagacgat tgacataaac attggccttt tgacgtgcat taatatcatc
     1381 tttctcaatt tgtgtcaggc gctcactaac tgaaatttgc tcatcttcaa tatcttttag
     1441 ttgagtttgt aaatcctcaa gattttcttc aagaactgaa taagcttggg ttggttcttc
     1501 ttgatttgaa gttacctcaa caatagctgc ctcaaaactc tctaattctg tctgaatacg
     1561 acgaacatgg cttgcagctg tctcaggaag taaataggtc ttgttcaaac gtgcaatatc
     1621 ttctcccaat aaagtattat tctctttcat atgttgaagg taagttggaa gagttgcaag
     1681 tagattttcc actactttct gagcagcaat ttctcgagta aaaatatcat acaaggcatt
     1741 gatttcctct tgtgcctgtc cattctcata ttcggcatta tccaattcca actgacgaat
     1801 attctcttgg tttttcttga atgcttcata aagcaagtgg aaacgcgctt caatatccgt
     1861 ttcaacaaaa tgataattag catcaattag tttacgataa ccggcttcca aatcctgtaa
     1921 ttgatctggc aattctgtag aaagcgtcgt aaccaaggct ggaacacgat ccacaatatg
     1981 acttaaggcc aaaatgtgat tttctgtatt atccaaaatc actgcggctt ccacagggtc
     2041 acccgatgaa ttcaaggtta caaattgtga aaattcagat tggatatttt ctaattgttt
     2101 ttcaatttca tccaaggctt gaccatactg ttctgaattt tcagcaactc tatgctgaag
     2161 ttcctcaaat aaatccaaag catgaagaac acgaccacta tttttagatt cttgcttctc
     2221 taagtctgcc aaagcattgc gaattgccgc aatatcttct tcaatcaaag taatttgact
     2281 ctcaatttgg tcaatttgat gactggcctt gagaaaacga aatgaatggt tatagccttc
     2341 tgcttcaaag agattatttt caatatcggc aaaagagttg agagataaat cgacccattt
     2401 ttgattccat tcacggaaag ccacttgact ttgtccaatc aagtgcatat tttttacagc
     2461 ttctacttca tcatttactg gaagattgta tagttcttct tttctttctt ctagcgcctc
     2521 taatctcccc tcgtttcgct tacgtagaaa gattgccact acataagcca gaactaaaat
     2581 gactgcaatt gcaaccatta aataaattag ttgtccatta gacatatcaa actccttttt
     2641 tacttgaaac aatcgtaacg attatatcat attttttaga ccaagggaac tacttctccc
     2701 tattttttag acatcaagtg tactatagac agcattttct tcgataaact cacgacgagg
     2761 ctctactcga tcccccatca acatatcaaa gattttatct gcttctgcag catcatctac
     2821 agaaactcta gccatcaagc gatgttcggg atccatggtt gtttcccaca gctgatgatc
     2881 gtccatttca cctagcccct tataacgctg aatagtcggt ttggtacgac cttcactata
     2941 acgggctaaa gcttcttgga gtttgatttc ttgatctgca cccggctgga tatattcttt
     3001 aatctcgctt ccaaccttga caccatagat tggtggttgg gcaatataaa catagccagc
     3061 ttctaggatt ggtttcatat aacgataaat caaggttaaa agaagggtac gaatgtgggc
     3121 tccatcgaca tcggcatcgg tcatcaaaac gagtttttgg taacgggctt tcgaaacatc
     3181 aaattctgcg ccaaatcctg ttcccatggc tgtgaaaaga ctacgaattt cttcgttagc
     3241 tagaatctta tccatacttg ctttttcaac gttcaaaatc ttaccgcgaa ttggaaggat
     3301 agcctgaaac tcacggttac gaccagattt ggctgatcca ccagctgagt ctccttcgac
     3361 gatgaagagt tctgtttcag cagggttatt agaagaacag tctgctagtt tccctggaag
     3421 gttggaaatt tccaaaccag attttttacg tgtgacttca cgcgcacgct tggcagccac
     3481 acgagccttg gcagccaaaa ttcctttttc tacgatacgt ttggcaatct gtggattttc
     3541 catgaggaaa tcggagaagg cttcactgaa gaggcgattg gtaatcttga ccacttcgct
     3601 atttcccaat ttggtcttcg tttgtccttc aaactgtgga tttgggtgtt taactgagat
     3661 aactgcagtt aagccttcgc gaacatcttc ccctgttaga ttgtcttcat tgtctttcag
     3721 taacttattc ttacgagcat aatcgttgat aacacgtgtc aaggctgtac ggaaaccttg
     3781 ttcatgcgtt ccaccttcat gtgtatgaat attattggcg aaactcatga cattttcatg
     3841 gtaacccgtt gtgtactgca tggctacctc aactgtgata tcatccatct caccgtctgt
     3901 atagattggt gtatcaaaga ttacatcctt gttctcgttg atatattcaa cgtaactagc
     3961 aatcccacct tcataatgat aatgcttggt ttgttccaaa ccttggcgct tatcagtgat
     4021 agaaatttga agaccgcgat ttagaaaggc caactcttga atccgtttat ttaatttatc
     4081 aaaatcaaag attgttgttt cagtgaagat ttttgggtcc ggtgtgaagt gaacagttgt
     4141 tcctgtttta tccgtatctc caactatttc aagatctgcg acaacatgac cacgacggta
     4201 ttcttggtaa tgaatcttac cgtttttatg gacatgaacg tctaattgag tggaaagggc
     4261 attaacaact gacgacccca ccccgtgaag accacctgaa accttgtatc caccaccgcc
     4321 gaactttcct ccagcgtgaa ggactgtaaa gacggtctca acagcaggac ggcctgtttt
     4381 ttcctgaata tcgactggga taccacgccc atcatccaca acagtaatcg aatcatctgg
     4441 ctcaataaaa acttgaatat ggctggcaaa tcctgccaag gcctcgtcaa ttgagttatc
     4501 aacaatttcc cagactagat ggtgaagacc ttcttttgag gttgatccaa tgtacatccc
     4561 tggacgcata cgaacagcct ctaagccctc taaaacttga atttgactgg catcataatc
     4621 ctgtgcctgc agatttttga tttcttctgt catcttattc ctttttctta tatgtctaat
     4681 acttgtctta aatttacgat actggtaaac aagtgggtat caagtcctgc agcttgacct
     4741 gcttcgatat caatcggccg atcaccaatg acaagaccag agctaatctg atacttttct
     4801 cttaaataaa gcatggattc gggatttggc tttctcttaa agcctgagct agaagtcacc
     4861 acttctgtaa aataagctgc tatagaggtt ttttctaaaa tttccaaaac ctgatcattt
     4921 cgatgagaga ccaaaaaatg acggccacct tgatttaaaa tgtcttccaa taggtcagaa
     4981 actccttcaa ataaaatcgg gtgttcaagc tctctggctt cattttcctt gtacttttct
     5041 aaaaaattct ctaaattggg agcgaatgtc tcaatcgcaa aaggagtaga aacctttaaa
     5101 gcttgataga cactgtcatg gtcttgtgtg ataccataca gtgccaatgt ttcaacaaat
     5161 gcagctgttg aagtttcata attatccagt aaagttccac ctaaatccca gatgtaatcg
     5221 tgatatttca tacccttcat tatagcattt ttttatgaaa aaagcgatga tttccctgag
     5281 ttttccacat aaaaaacgag agaataactc ccgttttact gatttttacc aaagacatct
     5341 cgatagagca ttcctgttcg taaactctct gcgtcccctc ctagttgctc caccaactcg
     5401 taggcaaagg caagggctgt tgaaggaccc cgactggttg tcaactgacc atctaccact
     5461 actgtttcct tgacgtagtg accatcaaga atttgctctt gaacgccgtc ataacaagtg
     5521 tatcgcttat ttttcaatat ctctgcttga ttgagggcaa ttggtgccgc acaaatggct
     5581 gctagtttct tcccttcttg ctcaaagctt tgcaattctt gaatcaaggt ctgattatca
     5641 cgtaaatgtg cagaaccagg catacctcca ggaagaacaa tcatatcata gtctgataaa
     5701 tctccatcaa agacatgatc tgctcttact tggattgcat gcgaacccgt tacttgctct
     5761 tcaaaaccaa ccatatcaca tgtgatattg gctcgacgca agacatctac aactgtcaag
     5821 gcttcaattt cttcaaagcc ctgagctaac ataactgcta cttttaccat gattttctcc
     5881 ttatttaatt tgttttaata caaccttttt ccgtttgaat gggacttttc cgctcttttc
     5941 ttcagctaga ttagtctggt aactcatcga taaaagcaaa ccaacaccaa tcagattact
     6001 gataatagct gatccccctt gcgaaatgaa aggcaaggga atccccgtca aaggaagtag
     6061 tccagtcaca gcaccgatat tctcaaagat gtggaagagc aacatcataa tcaaacctgt
     6121 ggaaatataa gtgtagaact ggttatttga tttaagagta atcttcaaca tacggtaaat
     6181 caacatgaga tagagggcaa taaccaggac agagccaata aagccaaaat cttctgcaat
     6241 aaccgtaaaa atcatatctg actctcgaac tgggataagc agattcgaag cattaaatcc
     6301 ctgaccaaat aagccaccac tcccaatggc aatctgccct tgagcctgct ggtaagtcgt
     6361 tgtttgggca aactcaaagg gattgagcca agccaaaatc cgattaattt ggtaggtcgg
     6421 cattccaatc tggtgaagaa aagctcgtcc gtccttgcta ataaagatag ctaagaaacc
     6481 agcaactcct gttacagcag tcacaaatac tgggataata attttccaag aaacccctga
     6541 taataaaacg attcctgaga aaatggctac aaaaaccaaa gccgtcccca agtcactttg
     6601 aagtgctaaa agaactagga ctggaatggt aaagagaatc atccagaaaa ttaacaaaaa
     6661 gtccagcgga accgtgcgtc tccattcctt atgtttcttt gtaaattgga caatgacacg
     6721 agccaacatg aggatatagg atatcttcat aaattctgac ggttgaaata gggtaattcc
     6781 atttattgat acccagtttt tggcacccgt tgatgcaact aagcttggat tataaaatac
     6841 aatcggcaag atcataagtc ccaagcctaa aatatataga aagggggtca ccttccaaag
     6901 aaattctgta ttaaagagca tgaccacaaa accaatcaca agccccaagg caatccaggc
     6961 gacctgctgc cctaaaatgg gcagaatatt attgggataa tcatgactaa cggctatata
     7021 gatagccacc acaccgatga ccagtagaaa aaatactggc aagagcaaac tataatcgac
     7081 tctagagtcg agagaacgtt tcatatgtac taaccttata ctttcataca atactattta
     7141 tcaaagttca ttaaaaaatc tatcaatagc ctcgtcaact tcggatcgag agatggtttt
     7201 aacagtcgct tcttctgcta gagatgctac tatttgtttg ccgtatcgtt ttccgatgat
     7261 tctcctatcc aaaataagag ttaaggaacg ttggtattca cgtctcatac ttcttcccaa
     7321 agcctgtttt aaacgaataa tggccattgg caattgataa tcataaaagg catttttccc
     7381 ttcttgattc agttcttgat taatcttttt cgtcaagggt tcttgaggat tttggaaagg
     7441 aagcctcggt acaacttgaa tcacaaaagg atggcttgaa aaatcaactc cctcccagaa
     7501 acttgctgca ccaagcaaga tttgttgttc acctttttca aagcgtttct ttagctgatg
     7561 aacatcccca tttttatact gggccaagtg gccaactgta agtaaatccg atactgctag
     7621 aagcatgtct ttagcggtaa agagaaccaa aatcggttgc tggaaagctt gaatttccac
     7681 tagtaaagca gctacctctc tggcatagac ttctaaggag gtttctgtta ccagagggaa
     7741 atctttgacc ataaccactt cttgttcctg ttttccccga gattcaatct tgacaaattt
     7801 ggcttcagga tagcctaaaa ggtctgccaa agaaaccctc tgactaatct caagagtagc
     7861 tgatactccc aagacttggc aactctcagg aagtaaagag gacagaagag tacggcctga
     7921 ttttgtagaa gaaatctgaa ttttcttttg actcgtttca gttacttcaa gccagtaatc
     7981 accttcagct gtaaaatagc gaaccagctc atcaaagtct tctacttcca attctgaaaa
     8041 atactgatgg agattgtcca gagaatctaa gatatttttc ctagatttgc cagactgaaa
     8101 ttgttctatc aagtagagac actcaaagcg aatactttct agtatccgtt gttgaaccct
     8161 gttttcttct cctactaaag ccttatcaat taaatcgata atagattgta tatcgtaggt
     8221 ctcttgaagc agattttcta gagctaacaa aatcttttgg acttcatcaa taatcagtaa
     8281 acggtcactg acaaattcag gattatcttc aagtctggtt acgagatagg catgattagt
     8341 cactaaaagc ttgcaagtct ctgccctttc ttgactacgt ttccaaaaat cttccgtcac
     8401 aaataagctc tgggatgata aattcccatc atgacgaagg tctgctagaa aatgttggta
     8461 acggtagagt tgcccgattt catccaaatc tcctgtctct gtctcagtaa gccagaccaa
     8521 gacttgcatt ttaaagcgtc taaataagcg attttcatca ttttcctgca aggaatgata
     8581 aaaggcatcc aacttcagat aattttgtgg tccctttaag ctatgaatat ctgtatggaa
     8641 cacttccttg aggcgtttac cttcttcttc catgatttga ttttgaagaa tctttgtcgg
     8701 aacactaaga acaatttgtc gctctttgga ttgagataaa gcgggtaaga gatagccata
     8761 ggttttccca atccctgtcg gcgcttgaat cagagagaca ggttcatctt tcaatagcaa
     8821 gccaacctct ttagcaaaac tttcttgttc ctccctcact tcaaggttca acagagaaat
     8881 atttttagaa aagtcttgag atagttttcg tggctccaga gaagcttccg ttttcttaaa
     8941 atatagacct tgaacttgga ccaagtctgg agaactcagg atagattggt tgcgataagt
     9001 ttcctcaata accaggtagg actcatatag gagagcgtca gccatttcca gcaagcgttc
     9061 caagagacct ttaggaagct gggtcatctt tttccgtaaa aaaagaagta attctgctgt
     9121 agcttgggca tctgaaaggg ctgtgtgtgc gtgtttaaga ggaattccta attctcgaca
     9181 caaaatcggc aaactatatt tttccagttc agggaaaaag acctgggcca attcgaccgt
     9241 atcaacacga gggtttctta gctcatagcc ttcaaaaaat aaattttccg ccaagagatt
     9301 agcatcaaac tgaacattat gggctacaaa aatcccatcc tccaccaagt caaatatttt
     9361 tctggcaact tgcgaaaaat caggtgcttg cgccagacgt tggtctgtca atcctgtcag
     9421 ttctttgata tgagcatcca agggttcatg tggattgaca tccgtcgtat agtgatcgac
     9481 gatttctccg tcctcaatca cgacaattcc cacttggata attttagcct tactacctgt
     9541 gctagttgcc tctaaatcca ccacaacata gcgattacca atcgttttca ttataaaaaa
     9601 ttataccaaa aaaagggcca tttggcacct gcaaacatag gataattttc aaactcaaga
     9661 acactacttt tcttaaaaat cccatcgaat agagcattct agcctgctga tttttgtaaa
     9721 atagtgaaga aatacgaaaa attgagagaa gaaatgtttg catcttcctt ctctcaacga
     9781 atcatgtatt ttatctaacc atgtcaggat cgtagtcata aaatcctgta tcaaggaaac
     9841 ggtttttagg gtgaagttta cgaacttctt catccagcaa gaaggcttga gcatgactaa
     9901 agttgccctc ttgaatcaag ctacgcgctt ggataaagag ttttgcaatc tcaacaaagt
     9961 tctgaccagg agtgtagagc ccttctagtt tccagcgagt aaagccatgc tccaccaatt
    10021 ctgttaattt gatcatcaaa tcaaggtcat tgttggcaaa gatatgggtc ccatgattat
    10081 cttcaaaaat ggaatagtgg ctctctggat cacttggctc agccaagaag aggtcacgtt
    10141 tatgcgtctt ttcatcatcg atatgtgtaa agttatagta gttttgcaag agtggacgtt
    10201 tagaatgatg gatgacgcta gcaccgtaaa ccaaaacttc agcaggaatt tccaaaatct
    10261 ctggcatttt gaaaagttca gctgatggaa tttcacgcgc caaaacagcc tcagatgcgc
    10321 cagccttttg tccccagaag ttaatctgac gactgctagt taccatggtt gaagcatcgt
    10381 agatggtctt aaatgaataa ccatcgcggt taactacgta aaagacgcct gcatccccaa
    10441 tcgtaatata gtctgtcttg atttcttcca agaagtctaa gaaaggcttg atacggtcca
    10501 tcatatcttg gtgcatgaga gcattgaccg caacgatcaa ttccttacca gcatcatgaa
    10561 ccaacttagc gatttcacgt aattggtcat aactaaaggt cgttggcaga cgaagaccaa
    10621 aatctttctc accgacatag atacggtcta cgccagcttc gagtagttgt tcaacttgtt
    10681 caatactttc agcagttgct gtaatgacaa tcttttccat aagaaaaatt ataccacatt
    10741 tctccaaaat cagccatgct ttgaaaatga aaagggactt tattcttttt gtaacctttc
    10801 tgtaataatt ctctgccgaa aaaatgataa aataggtatg tactgttaag gagagaatca
    10861 tgcccgtaag aaaattacaa tcctatgagg tagactatca agaagaatta aaccagcagc
    10921 ttcctcatta ccaagcttat acacctgaag cgcaatctga tgccaatctc aaggaaatcc
    10981 tattttttat taatatcgct gttttttgta tctgtattgc tatctttagt tttatctttt
    11041 tagcattaaa attatcaact gctcttgcct ttgccgcagc aatcggattc agcttacttg
    11101 ttttaaaagt tcaacggtct attatcaaac gaaaacgtag aagataaatc caaaatatcg
    11161 ccccaattgg agcgatattt ttattttttc tttttagatg gtgtctgaat ggcaatcttc
    11221 acttcaaaga ttgttccctt gggtttatta tctttgacag taacagttcc ttttagagca
    11281 tctacaattt gcttggctag ggataatcct aaaccaaaac cacctttttg ccgggttcta
    11341 gccttgtcta ctcgataaaa acggtcaaaa attttctttt tatcttctgt cgaaataccg
    11401 attccattat cagaaacaag taaataaaga ttgcgatcgg tcgccgagat aagaaaatca
    11461 atttcaccat cctcctcagt atacttgacg gcattatcga aaagaatggt catcagttgt
    11521 ttcagaagaa gctgatctgt gacaattgtt cgatggatac gattttcaaa acggaagaca
    11581 cgattatttt ccgaagcaat catctcatag tttgtgaaag ttgtattaaa aaagctagtt
    11641 ggaacttctg caagctccgg cttaatccca tcatctctcc gagctaagtt cagcaagctt
    11701 gtcgttaaaa aacgcatatt tcggacttct tccaaactcg atgcaatgct ttcgctcaca
    11761 tccataatgg tagcttctgg cttacgaaaa agggtctcta agcgattttg caaaactgcg
    11821 agtggagttc gtaactcatg actggcattt tccacaaaag actgttgctt ctgcatactc
    11881 tcaagcaggg gcctaacact gaccctagct agatagagac tggcaagtaa agacaaaatc
    11941 cagaaactag ccatcacgac cacaatcaat tgctcatgct tttgactagc ctgctccaac
    12001 tgactggtat taatcaagac agcagcatac ttgatattgg ttgaaaccga actaatattg
    12061 gtctccatca aaatcacacg atagatttct tcctgcccat agctattaaa aacctgaatc
    12121 tggtagatat gtcctagttc tttcttttct aacttaatct tatccaagcc caaaaatcga
    12181 tttccagaaa gaagttgagt aaagtcttta tcaaagagaa tgacttccgt attggaactg
    12241 acattaggtt ttatttctac tttactagcg tccgccctag cattttctaa atctttaatc
    12301 tcttctgttg ccctatttat agccagctga ataactgctt gaggattttc actcagtcca
    12361 tgaagcttat cgtccaccga agtataaaga ctcgaatgca tgacttgtaa aataatcaga
    12421 gtcattgtag aaaaaatcag ggtgaagaca ccgaagttgc ggataaaata actaaagtca
    12481 tccgcatacc atgttttttt aagtttactg aacatctttt aaaagatacc caacactacg
    12541 caaagtttgc aaattctctg caaaagtggt tccctttaat ttcttacgga cttttgaaac
    12601 atagacttcg acaaccgaaa tcgttgtatc actatcaaat ccccatagac ggtcaaaaat
    12661 ctgcgtctta ggcaaaatca cattttgatt ttgaaggaaa taaactagta agtcgaactc
    12721 tttccccagc aattcgacag gagtatcttc aactttaacg gtattggttg ataaattaac
    12781 cacgatattc ccataagtca aggtgttttc attaaacttc cctgaacgtt tgagaagggc
    12841 ctgaatccgc attttaagtt cttctaggta gaaaggtttg gtcagataat catccgctcc
    12901 cagttcaaat ccatgtccct tgtcatccaa actttccttg gcagtcataa tcagaactgg
    12961 tgtcgtaatt cccttttcac gcaattcttt taagacttgg aaaccatttt tttctggcaa
    13021 catcaaatcc agcaaaatca agtcatagac accactctca gcttcgtaga gaccttcttc
    13081 tccatcaaat acctgcataa catccgcaaa atcgtctaaa aagtcaaata ctgaatttga
    13141 cagacctagg tcatcctcaa ccaataagat ttttatcatg agaaactcct ccttattaaa
    13201 actattatac caaatttgcc ttaaaaaaaa ctcaactctc tgcattttac atgagatagc
    13261 tgagttttct ttttatttta ggcttattta tgcatttccg tattgaagaa caactgcttc
    13321 gactgcagct ttttcacggc taatcaagtc aacacgtgct gcaatttcct tgattcccat
    13381 accgatgtta cggctaagag caaggtcaga aagttgcggc tcaaagaact ccttgtattc
    13441 cgccaagcgt tgctgagtct taaatacatg agcaggaagg ataacaaagc tatcaaagct
    13501 catatctcct ccaagggctg ccttaatcca agcccagttt tcacgcgccc aagaccaagc
    13561 tgttttctga gttgcttgat gagctaggaa ttggtaatac caagcagaca agtcctgtgg
    13621 tttgaccaca aatttgtcct tccaagaagt aatcaggttt tggatattat ccgcatctgt
    13681 actgtatgca agagctgctg ccaactggcg tttaaagaca gcatctgttg cgtgagtata
    13741 agtatcaaga taaagtgcta acaagtcttt agtctcatga tgtttcatct cattaatcag
    13801 aacttgtgag cgaatagctg ctgggagtcc tgcaagattc tccttgtgtg ttgcgaagat
    13861 ttggctagcg acttgactag cttctgcatc atttgagcga atcatcatcg aaacagccag
    13921 ctgacgaacc aattcatcct catctgattc tccgtcttta gcttcaaaac caagacggtc
    13981 atagttatga cgagccaatt tagcaaccag tcctttgaag gctgtttcag catccgttcc
    14041 ttcatcaata aagcgctcaa gggctgaaat cacttgagaa acagctgaaa ccaccagata
    14101 agactcttcc ttagcaagtt tatcaagaac tggaagcaag tctgcataag aaatgtgccc
    14161 tgcctcagcc aacaaacgac gttcttgaac aatttgcagt ttgcttgtgt tatcaagtgt
    14221 ctctagctca gcaagaacag cttctaacaa gtctccttga tagtcggtaa tatagtgggc
    14281 agtattttca gtgttgagac gaagagctcc ttcattttca gcaagaagag ctgcgtagcc
    14341 agggatttcg atactttcag tttcgagtgt atcaggcaag cctttccagt tgctattgag
    14401 gggcaccacc cagagacggt tcttgtcttc gttctcaccg atgaagaatt gtttttgtga
    14461 aatcttcaag acatcatttt caactttgac agtaagaact gggtaaccag gctgttccaa
    14521 ccaagaatcc atgaaggctg cgacatcacg tcctgacgct tgaccaaggg catcccaaag
    14581 gtcactacca atggtgttgc tgtattggtg tttttcaaag taggcgtgca aacctttagc
    14641 aaaatcagca tctcctagcc aacggcgaag catgtgcatg agacggcttc ctttggcata
    14701 gacgatagcg ccgtcaaaga gtgtattgat ttcatctgga tgtttaactt cgacgtggac
    14761 agactgaacg ccatcagtag cgtcacgttc aagagcaaga ggtactccac ctgtttggaa
    14821 atcttcaaag atattccagc ttggttcgat ggtatccaca cagacgtatt ccatcatatt
    14881 agcgaaactt tcattgagcc aaaggtcatc ccaccatttc atagtcacga ggttcccaaa
    14941 ccattggtga gccaattcat gggccacaac aagggcaact tgttgacggc tagcaaatgt
    15001 agagttctca tcgacaacca agtaaacttc acggtaggtc acaagacccc agttttccat
    15061 agcaccagct gagaagtcag gaagggcgat gtggagagat tgaggaattg ggtacttaac
    15121 tccatagtaa tcttcgtaaa actcgataga gcgaacagcg atatccagtg agaaatcaag
    15181 atttgaaagt ggatgtgctt tggttgagta gacacctacc agggtaccat ttttagtttt
    15241 agcggtcacc ccttgcaaat caccagcaac aaaggccaac aagtaagaag acatgcgagg
    15301 tgttgtctca aacttccaga tacctgtttc cttacggttt tcaacatcga tttctggcat
    15361 gtttgacaag gccaattcac cttctgcttg gtcaaagcga agagagaggt caaaagttgc
    15421 tttggcttca ggctcatcca cacatgggaa agcttcgcgc gcaaaatggc tctcgaactg
    15481 agtagacaag acctccttct tgactccatc aactgtataa taggaagggt aaatccctgt
    15541 catgttgtct gtaattttac cagaaaaggc aagaaccaat tcaacttgac cagcctcagc
    15601 caattcgata tgaagggctt cattgtcatg gtcaactgta aatggacgag cttgacctgc
    15661 aacttctaca gaggtgattt ccaagtcttt ttggtggagg gagatgcggt cactctgtgc
    15721 ttgaccagtg atggtcactt tcccagaaaa agtcttggtc tcacgactca aatctaaaaa
    15781 taaatcataa tgttcaggaa caaattgctt aataaaatgt tcaactgctt gcatagtttt
    15841 ctcctattct aagtttaaga gctgctgctc ttcttaaaac aaacttatta tatcatattt
    15901 tgcttgagaa aaaaggattg gacagcgatt tccaaaactt tcttccttct aatagtctac
    15961 agtgggtaga ccttgcgaaa ttcttctaaa acaaccttgc tttcaggtgt aaaagtcagc
    16021 cctacttcac ccaaacagtc tgtgaaaaag tcctcatgaa cctggcgcca ataggcaagt
    16081 gatttgtctc cctcaccttc cttaaaggca tgttgcgcag aaacttgatt gaagagttca
    16141 acagaaacct ttgtaatttc gacaacgcag acagcctgat tttgactatc taaaatgaca
    16201 tcgaaggtcc ctacttgggg aagtggttcg tcttctagta catagaggtc ataggctgat
    16261 gctgttgctg tcttttctcc tttaaacacc aaatccgcta aaaggtctgg ttcaactcca
    16321 aaagcccaag catcgatttc atctccgatc aaaggattga tttgcttgta tttattctac
    16381 atttcttgcg gtatcatggg tactcctttg taatttttta ctttcttctt ttatgtgttt
    16441 aagatgatct ggatggtcaa tctctaaatc aaaaatctct ggaatagaac tgtagtggat
    16501 aatgcacttg atacccaact gattcatttt ttgtatgaaa gaagtattca gatagcctgc
    16561 tacagcaaaa ttaatcttgt tctttcttgc tttatcctgc atatctctta gcatatctaa
    16621 cattattgga ctttccatat catgccattg actgtttctc atagtcgcaa aaacaaagga
    16681 agtcaaatca ttcattccaa ctacaatctt tgaaatgccc gtttccagta tactagataa
    16741 gtcaaaatac gctgacggta attcaatcat cgttccgact ttcccagtaa agccatactg
    16801 acgcaatact gtaatagctt gttttaattg gtcggcatca ttgacaaaag gaaaaataag
    16861 agacagattg ggattggttt gataaacttc tgtaacgaca tgtgattcag cctgaaattc
    16921 atccaaacac gccagtaaac gcctggttcc tctatagcca aacaagggat gcccttcgtc
    16981 aaaaaactct ctagtccccg ctaaacaatt ggcttctgta ttcgttaatt cagaaaaacg
    17041 ataccaaact tccttatcta agtaaaagga gcaaatagta tcaagataat cttttacaaa
    17101 ttgctgacaa cttgctaata tgatgttttg attaagctct ctcaataagt attccccacg
    17161 aatcatgccg acgtggtgaa atagttgagg ataaattttt tcaagaattt tttcgccact
    17221 aagggcaagt tgatttctca tagccattca cctcgtctta aaagatacaa tatcatatat
    17281 aattatatca aaatttcctc tagttcaaaa gcttcataag gttcagataa ctcatatcct
    17341 aaaaattctg ctactttttt ggaagcctca ttatgagcat cccaaagtgg aaacatatct
    17401 ctatttaaac tctctagaat cattgcagca ccaagctttt tagcaaatcc atttccttgt
    17461 tcgtttggtc tagttgcaac ttccacttca actgctttac ggtaaactaa ccctgaggaa
    17521 atcccagcaa tcagttcatt atttttaaga atcacaaagc caaatccacc ttttaaaaca
    17581 aaatcctgat aggactcaaa atccccctgt aaatcctgtg accattcttc cgtagaaaag
    17641 cagttataaa tatgattatc aataggcaca atattgtaac cttcctctaa atgagtaact
    17701 agattattta aaaattcaac ttgaaaattt gccttatctt taaaagaata gcgagtaaaa
    17761 gaatttagcc ccacttttcg atgcagaaaa tcttgccaat tagtattttc tgaaataata
    17821 atcttataat ctaaaccata ttttctaaca aaatcttccc aaaatctgga atccaactcc
    17881 cctgctaggt atagaaaatt cccaacatca taaaagcttg ttgtcctatc attgtttcgg
    17941 tagacagttc caatttgaga tttaagacca tagagaacca tatttttctt ccatgtttta
    18001 aatagttcca ttatccctct acttcacctt ccaattcatg taagaagtct tgtccagttc
    18061 tggaaatcct aataattcag acttaacctt caagactaat ggcgatgcat tttcttctgt
    18121 aatctcttga atatccatcc aaatatatcc aagtgaatca ttcgcaccat cagacacagc
    18181 ttccgaagtc gtaacttgag gtgcactctc attcatttca acatcataca aggccatgac
    18241 atggtgaacc ataaaatttg ttaactcttc tctgacgaaa acatcgtaga ttcgaggatt
    18301 agagtagctt ctaacagtaa atcccgtctc ttccataact tctctagtca gcgtttccgt
    18361 cagtccttca ccaagttgct gactgcctcc aggtagatca taccgatgtt gataagggcc
    18421 tctcgctttt tcaatgcaga gtaacttccc attttctaag caaacagcgt agactccaaa
    18481 gtgttttttg atttccatcc aactcctcct acttcaaaga ccagccacca tctattgtca
    18541 agatttgtcc ttgcatggcg ctcgcttttc cacttgctaa aaaaagacta agctctgcta
    18601 tttcctctgg ctcaatccag cgcttgattg gggtttcact agccacccag tcagccaaac
    18661 cacctggttc aaaatccgca gcggtcatag ctgtcttgac tgctcctgga gcgatcccaa
    18721 agacctgaat cccagcttca gcatagtcta gagccaactg cttggtgaag ccagccaagg
    18781 catgcttgga tgaagtatag gcgtgaccac ctccacctgc taggctagaa gcaatggaac
    18841 acatattgat gatgattccc tttttatttt ccagcatttg tgtcaaataa taccgagtca
    18901 actctactgg aataatgtag ttgatttcaa aaatctcttg aatgtcctgc gccgtttgtt
    18961 ccaacagtgg tttgtaatca tccaaaactc cggcagtatt acacaaaaca tccacctgag
    19021 ggcaccagtc aaaaataggt tccaagtcca aggtcaaatc tctctgtaaa aagtgaaaat
    19081 caccctctaa gagtggcttt tcaccttggt caactccata aacttgatag cccttctcta
    19141 aaaagaggcg agcttgagcc aatccgatcc ctgaactcac tcctgtaatg agtacacgtt
    19201 tagtcatgca cttctaccca atccgttgcc aaaacatcac aagctgtcgg gctccacatg
    19261 gaaaaacctt ctccttctcc agacacgttg attaggaaat aaggtgtcat ttcaagtgca
    19321 agcccatttt gctcgatggt atcaaagagt tggacatagt tttccgcacc tccccaacca
    19381 gttcgtacat attttctctt agcctttaac ccaggcagga tctcttcaaa tgtcatgttt
    19441 ttctccttta attctacatt cttcatttaa ttataacaaa aaaaccgctt taaaacggct
    19501 ttttgactgt gatttattta catcttcttc tacttacggc aaattattcc ctgcagcaag
    19561 ataaatttca taccattctt ttcttgttaa gctaaagttt gccgcttggc taacttctct
    19621 caagtgctta ggatttgtgg tacctacaac tgcctgcatt tttgctggat aacgcaatat
    19681 ccaagaaatg gcaatagttg aagaggttac tccatattta atagctaaac gatcaagtac
    19741 ttgatttaaa gcttgaaatt tctcatttcc aacaaaattc cctttaaaat acccgaattg
    19801 caagacagac catgcttgaa tgaccacatc gtgtaattgg caatattcaa aaatgctgcc
    19861 atctcgcata gctgcttgac tatcttccat attaacatga aaagctgatt caaatcctgg
    19921 agtaaaagcc gcactcaatt gtagctgatt aacagctaac ggctgcttga catctttttt
    19981 aagcaactcc atcatcatag gattttgatt agaaactcca aaatctcgaa ctttaccttg
    20041 tttataaagg agattaaagg cttctgctac ttggtcagat tccatcaaag catctggtcg
    20101 atgaaggagc aagctatcta gatgatcaat cttcaatctt tgcaaaatac cgtctactga
    20161 ttttataata tagtccttag aaaaatcaaa ataggtaaat tcttcaatgc gaatgccaca
    20221 tttggactga atccacatct tttctcttaa atctggacga ttttttagga caagacctaa
    20281 cagttcttca caacgaccac gaccataaat atcagccaag tcgaaggcat tgattccaac
    20341 agaaagtgct gtttctgcaa gctcttcaac ttcttttaca gacttatctt ttattctcat
    20401 cattccgaga acaatttctg ataattcttt gtcatcttga ccaagagtta tgtatctcat
    20461 caaatttttc tcctttaatt tctaacattc ttcccttcat tataacaaaa aaccgctttg
    20521 caacggcttt ttgactatac ttcactccat tttatcttct taaacccacg gaacaagaca
    20581 aagattccaa taaagaggac agctaaagga ataacttttg taaggaaaac atttgaaatt
    20641 cccatccact cataataacg gagcagagaa cccaccacaa gatgggcaat aatcatactg
    20701 acaaatggac gaaagaccgc ttctttccaa ttccaaatac cgataactag cgaaatcgta
    20761 aagacagaca aactatccca gggagccgga atataaaagg ctccttcttg tatgaagctt
    20821 gccattccta catatcctaa aacaactaga agaactatag tcccaacaac aatgtaagtg
    20881 ccaattttca ttttaggaga atcttggact aaacttcttc gtaaaattgt ggccacaagt
    20941 ccaaatccaa tcagaaaaat aagaagttgc cctaaaaatg tgagcaaatt gactgttaag
    21001 agaggacctt tagaaaaatc acttagtagt tgataataac gtaataccgc caggacaaga
    21061 attggcgtca aaagggactc tttgatagaa ctgcgaggtg ctcccttgag aatctctttc
    21121 attatttttt taggattctt acctagataa tcctctgcac tcatgccatc tcgttctgct
    21181 tctgagaaat ctagcatcat caaatagatc tgctctctga gatagtcttc atcatagaga
    21241 aatccagcaa gattaaaact ttcccacaac tcctcaaaat acttttgatt ctcctcagaa
    21301 aactcatgta gcaaagcgct tgtttcttcg taatacttca ttttcttcat ggtttaaccc
    21361 ccattcttaa tcccttctac tttttgactc aaatcgtccc attgttgcca aaagactgag
    21421 acacgctctt ctccttcttt cattaatgaa aaatacttcc gatctggacc atctggcgac
    21481 gggcgcatgt cgcctcttat ccattgattt ttttctaact tttgcaacaa aggataaata
    21541 gttcctggaa cgatagtatc aaatccagcc tctcgcaaag tctgaaccaa ctcataacca
    21601 taccgctctt tttgaccaat catatccaag acacaacctt caagaacacc ttttaatagc
    21661 tgagtttctt tcatcacttc tcccttctaa tctattttgt aatacctact agtaacttca
    21721 cctatagtat atcacttcta cactagtttg taaagcataa tagttaatac tcttcgaaaa
    21781 tctcttcaaa ccacgtcatc gtcgccctac cgtatgtatg gttactgact tcgtcagttt
    21841 catctacaac ctcaa
//
LOCUS       DBERPV010000034        18659 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.34, whole genome shotgun sequence.
ACCESSION   DBERPV010000034 DBERPV010000000
VERSION     DBERPV010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 18659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18659
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.34"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..995)
                     /gene="lytB"
                     /locus_tag="ACL8C7_001626"
     CDS             complement(<1..995)
                     /gene="lytB"
                     /locus_tag="ACL8C7_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HGS1395784.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGG"
     gene            complement(1037..1975)
                     /locus_tag="ACL8C7_001627"
     CDS             complement(1037..1975)
                     /locus_tag="ACL8C7_001627"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HGS1395785.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            complement(1986..2786)
                     /locus_tag="ACL8C7_001628"
     CDS             complement(1986..2786)
                     /locus_tag="ACL8C7_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HGS1395786.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLFEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            complement(3036..3416)
                     /locus_tag="ACL8C7_001629"
     CDS             complement(3036..3416)
                     /locus_tag="ACL8C7_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGS1395787.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            complement(3474..3833)
                     /gene="rplT"
                     /locus_tag="ACL8C7_001630"
     CDS             complement(3474..3833)
                     /gene="rplT"
                     /locus_tag="ACL8C7_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HGS1395788.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            complement(3885..4085)
                     /gene="rpmI"
                     /locus_tag="ACL8C7_001631"
     CDS             complement(3885..4085)
                     /gene="rpmI"
                     /locus_tag="ACL8C7_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HGS1395789.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            complement(4118..4648)
                     /gene="infC"
                     /locus_tag="ACL8C7_001632"
     CDS             complement(4118..4648)
                     /gene="infC"
                     /locus_tag="ACL8C7_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HGS1395790.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTMKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     misc_feature    complement(4664..4795)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(4955..6136)
                     /locus_tag="ACL8C7_001633"
     CDS             complement(4955..6136)
                     /locus_tag="ACL8C7_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395791.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIERWGSSRKKEVFK
                     V"
     gene            complement(6140..6727)
                     /locus_tag="ACL8C7_001634"
     CDS             complement(6140..6727)
                     /locus_tag="ACL8C7_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS1395792.1"
                     /translation="MLNLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            complement(6759..6947)
                     /locus_tag="ACL8C7_001635"
     CDS             complement(6759..6947)
                     /locus_tag="ACL8C7_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395793.1"
                     /translation="MTATKSYKYDWNTVLEYSTNYHDHQYAWIPEWSRYYSYSEYKVG
                     GGWNYARYEVINYYTGGY"
     gene            complement(7126..9366)
                     /locus_tag="ACL8C7_001636"
     CDS             complement(7126..9366)
                     /locus_tag="ACL8C7_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HGS1395794.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCL
                     FIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQNLVDSVERVRILPDTIKVNGDSL
                     SFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
                     LKTQGIYQTLNIKRIQSLQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLI
                     SLALVYDLRKNIKGLTVLSLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKENVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQTTQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            complement(9350..10000)
                     /locus_tag="ACL8C7_001637"
     CDS             complement(9350..10000)
                     /locus_tag="ACL8C7_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HGS1395795.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     VEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD"
     gene            complement(10068..10637)
                     /locus_tag="ACL8C7_001638"
     CDS             complement(10068..10637)
                     /locus_tag="ACL8C7_001638"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1395796.1"
                     /translation="MESIFVKLAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLVNPLGRWGIELKSNGQFIGTIDLHKIDSVLKKAAIGYI
                     SNKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            10814..11925
                     /gene="ald"
                     /locus_tag="ACL8C7_001639"
                     /pseudo
     CDS             10814..11925
                     /gene="ald"
                     /locus_tag="ACL8C7_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003018852.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0000286 - alanine dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0042853 - L-alanine catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            complement(12226..12551)
                     /locus_tag="ACL8C7_001640"
                     /pseudo
     CDS             complement(12226..12551)
                     /locus_tag="ACL8C7_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003032802.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(12554..13054)
                     /locus_tag="ACL8C7_001641"
     CDS             complement(12554..13054)
                     /locus_tag="ACL8C7_001641"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1395797.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGFDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIV
                     EQSLED"
     gene            complement(13247..14215)
                     /locus_tag="ACL8C7_001642"
     CDS             complement(13247..14215)
                     /locus_tag="ACL8C7_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HGS1395798.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(14301..14516)
                     /locus_tag="ACL8C7_001643"
     CDS             complement(14301..14516)
                     /locus_tag="ACL8C7_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HGS1395799.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            complement(14525..15379)
                     /gene="cvfB"
                     /locus_tag="ACL8C7_001644"
     CDS             complement(14525..15379)
                     /gene="cvfB"
                     /locus_tag="ACL8C7_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HGS1395800.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            complement(15439..15996)
                     /gene="frr"
                     /locus_tag="ACL8C7_001645"
     CDS             complement(15439..15996)
                     /gene="frr"
                     /locus_tag="ACL8C7_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HGS1395801.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            complement(16005..16742)
                     /gene="pyrH"
                     /locus_tag="ACL8C7_001646"
     CDS             complement(16005..16742)
                     /gene="pyrH"
                     /locus_tag="ACL8C7_001646"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HGS1395802.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            complement(16826..18160)
                     /gene="trmFO"
                     /locus_tag="ACL8C7_001647"
     CDS             complement(16826..18160)
                     /gene="trmFO"
                     /locus_tag="ACL8C7_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HGS1395803.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALINAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            complement(18405..>18659)
                     /locus_tag="ACL8C7_001648"
     CDS             complement(18405..>18659)
                     /locus_tag="ACL8C7_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395804.1"
                     /translation="IHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSGKIKYHE
                     DSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
BASE COUNT         5363 a         4250 c         3437 g         5609 t
ORIGIN      
        1 ccaccggatt tgaagtagta ccaagcttga ctatgagaat cgtagaccca ttctttttca
       61 gctattttcc catcagattt gaggtaaaac caagattcct tatcccaaat ccattcattg
      121 gctgtcatgt aaccaccgga tttgaagtag taccaggctt gactatgaga atcgtagacc
      181 cattcttttt cagctatttt cccatcaaat ttgagataaa accaagattc cttatcccaa
      241 atccattcat tggctgccat gtagccaccg gattttagat aataatagtg accattctcg
      301 aaaatccatt ctttatcagc atagtttcca ttttctttga tgtaaaacca agattggtat
      361 tgtttgtcaa aaagccaacc ttgctgtact ttggcaccac tagcattcac ataagcttga
      421 ttaatccact gacttgtcag tagataacca ccggatttga aataatagtc cttcccttta
      481 atttggagcc attctttctc tgcgtgctgt ccatctgctt tgatataaaa ccaagcatcg
      541 tattgagaat catagaccca gtcttctatt actttggcac ctgttgcacc aacataggaa
      601 gttcctaccc aagcatttcg tttcatcttt ccatcttggt caagataata aaaggctccc
      661 ttgtcttcta cccattctga tttggccata tagccaccag atttgaggta aaaatagtcg
      721 tcaccttgct ttagccattc attttcagca tagttagcat ctgcttttat atagaaccaa
      781 gattgataat gagtatcaaa aacccactca ttcgctgctt gactgccatc ttctttcaga
      841 tactgttttc cttgccaagt accatcacta gccattgcac cctctggact agctaagaaa
      901 aatagcagag ctaaaaaaat aaatcttact ttcttcatta accttcttcc tctgttctta
      961 tttattttat tgtaccaaaa ttctcctaaa ttcatattac aaactaataa aaaatcaaga
     1021 acagattgat tgcagtttac ctcagagact cttttacttc ctgacggagt tcttccagac
     1081 tgctaatacc gtatttatcc atgacttttg gtaaattttc gatgatgtca ggacaggcat
     1141 aaggattggt aaagttagct gttccaactc cgatagcaga tgccccagcc agatacattt
     1201 ctagggcagc ttcagccgaa tccactcccc ccattccaat gataggcagg tctgttgttt
     1261 gggctacttg gcggatgagt ttgagggcta ctggaaagac tgctggacct gacattccac
     1321 ctgttccatt ggccaagatt ggttttctgg ttttgaggtc aaagcgcatt ccaaccagag
     1381 tattgatcat ggtcaagcca cttgctcccg catcttctgc agcttttgcg acagtaacga
     1441 tatcggtcac actcggggtt aatttgacat aaactggcac ttctgaggct tccacagctg
     1501 ctttcaccac atcataagcc aaatctggat cttgaccaat caaaagtcca tgattacagt
     1561 ggtcaacatt gggacaagaa atattgagct cgatagcttt tacattagtt gccttggaaa
     1621 tcccatgaga aacagctgca tactcttgtt ttgaaaaacc agctacattg gcaataatag
     1681 gaagatttgg atattctctt tccagccaag gtagcttttc agccaaaaca acctctaaac
     1741 caggattttg caagccaatt gcattgagca taccagcagg cgtctctgcc actcttggag
     1801 ttggattccc aaaacgtggt tcaagggttg tcgccttgat cataatagaa cctaaaaggt
     1861 ctaaatcata gtacttggca tactcttgtc caaagccaaa acagcctgat gctggaataa
     1921 tcggattttt caaatccaaa ccaggtagag acacttgtaa tcgatttgta gtcataattt
     1981 tctccttata atacaactgt tcctgtgcgg aaaacaggac catcttcaca gacgcgttgg
     2041 ctgaccgtct cgctttctgg tacttttaga acacaggcat agcaagctcc catcccacaa
     2101 gccatacgag attccagaga taaataggct cttgggtgat catcaaaggt ttgattgata
     2161 tacttcatca ttcctggagc cccacacgag taaacagcat caaactgact atctaaatca
     2221 ttgataacaa cggaaacatt tcctttgatg ccataagaac catcatctgt cgttacaaag
     2281 acctgaccat actgagccaa ttccgttttc aaaataacag catccttatt agcaaaaccg
     2341 aggactgtca ctactttcac tccacgttca tgcaattcct tggccacctc aaacaagggt
     2401 ggaacaccaa tcccaccacc aacaaggaga acctgattct gctcatcaag gtcagacaag
     2461 tcaaaaccat ttccctgagg ccccatcaca tcaagagtgt ctccctgact taaggttgaa
     2521 aaaattgcag tcccagctcc ctcaatccga taaatgaggt gacactgctt gtttgccttg
     2581 tcaatagacg aaattgaaat aggacgacgt aagagatggg catcgtccgg tacacgcaga
     2641 tgaagaaatt ggcctgctcg catggcttca accatttctc cttctaggac taattcaaag
     2701 attgctggcg cgatttcctc ttgtgcaacc accttcatgg tttccaaccg aatgacaccc
     2761 aaacgcttct tacatgtggg attcataact tttcctcctt aaattttaag gggaccagat
     2821 aaagaaaaga ccttgctagt gcaaggcctc agttaaaatc gtacaacaca agagagcaca
     2881 ctcaaaaagt ctcctctaga aaattgcact attcttttat ctgacacctt gtgagtctct
     2941 ctggactccc cttaaaggtt gaatttttat tagtatactc tttcagctaa aaaaagtcaa
     3001 gtagaaaacg aatattctac ttaacttgca cgaaattatt tttcacgaat gacttcgacc
     3061 ttatatccat cagggtcttt gacaaagtaa tagtttggtg tagttcctgg tagaccattt
     3121 ggctcagtca cttcatagcc ttttgcactg tgttcttgat gaagtgcctc aagatcaggt
     3181 gtactgaggg cgatatgggc aaacccatca ccaaccacat acggaccgtg atcgtagtta
     3241 taagtcaact ccaactcata gtcatcaccc tcaagaccta gatagacaat cgtgaaggca
     3301 tggtctggaa aatctctgcg acgcaattct ttaaaaccaa aagcatcttg ataaaatgcg
     3361 attgattttt caagattttc tactcgtaag caagtgtgta gcatttttga agccatatct
     3421 ttctccttta tttttaaaaa gactggacaa tcctgttcca gtctcatcag ttgttattta
     3481 ccaagttttg ctttagctgc atctgcaaga gctgtgaaag ctactgcatc gttaacagcc
     3541 aagtcagcaa gcattttacg gttaacttca atctcagcca atttcaaacc atgcatcaat
     3601 tgtgagtatg aaagtccgtt catacgagct gccgcattga tacgagtaat ccacaatttg
     3661 cggaagtcac gttttttctg acgacggtca cggtatgcat agtagtaaga gttcattact
     3721 tgttcttttg cagtacggaa caagatgtgt ttagctccat agtaaccttt tgctaattta
     3781 agaatacgtt tacgacgttt gcgtgataca acgccacctt taacacgtgc catgttttat
     3841 ttcctccaaa tatttcctag aattgtttac ttacagtcaa gctattattt caagcgagta
     3901 agcattgctt tgatacgttt gtaatctcct gaatgcacca tagatgcttt acgaagatga
     3961 cgacgttgtt tcttagtttt tccgtggaaa cggtgagaag tgtaagcacg gaaacgttta
     4021 agtccaccag aacctgtacg tttgaaacgt ttagctgatg cgcggtgtgt tttttgtttt
     4081 ggcatgattt tttctccttt atttaacttt ctgacaatta ttttttgtca gtcgctggcg
     4141 ccaattgcat gaacatttga cgtccatcca ttttagcacg ttgttcgatg atggcaatat
     4201 cttgagttgc ttcagcaaac tcggctaaaa cttttgcacc aatctcttta tgggtaatca
     4261 tacgaccctt aaagcgaata gataccttaa ctttatttcc tttttcaagg aacttacgtg
     4321 cattacgaag ttttgtatca aagtcaccct tgtcaattgt tggacttaga cgaacttctt
     4381 tcatagtaac aacgctttgt tttttacgtt gttctttttg cttcttctgg tactcaaatt
     4441 tgaacttacc gtagtccata atttttgcaa caggcggttt ggcttggggt tgaatcaata
     4501 ctaggtcaac attagcgtta tcagccaaag cttgcgcttc actgagtggc ttgatgccta
     4561 gctgttctcc ctcaagacca atcaagcgaa cttcacgtac acgaatctca tcattgatga
     4621 ataagtcttg ctttgctatg gttttcacct cttttgtttt attagagaaa aacaatagcg
     4681 gactcgtaaa tatacaagcc cgcacgttat gatagcgttt cttcgaaact tttcatccgt
     4741 agggccaggc aacttaatgt cacaaggcga gaagctctca cttctgcttt tctcaacttt
     4801 tatatgatac caagttttct agctcttgtc aagataaaaa gttatttttt gaaaagtttg
     4861 tgtttgtatt ttggtttggt tttcgaatca aaaagagaga accaagttga ttctctccct
     4921 atgttagttt ttctttagct tccctatagg aaaactaaac tttaaaaact tcctttttac
     4981 gtgaacttcc ccatctttcg ataaatagaa tccccactaa caaaaggata atcaggcaag
     5041 gaagtaagac catccccatg ctccaattta gatcgacatt atcaatctgc ttagataatc
     5101 ttccagataa aatctccact gaacgcaagt aagtaaaggg aatcagatgt gcaatccttt
     5161 gaagaggctg aattgtttgg atgccaaaca ataagccaac aatcccaatg agtgaaagaa
     5221 agaggacagg cattttttgc ttgaaaaagt aagcaatcaa gtacacaact tccacaatga
     5281 cgataaaggc taagaaagct aagagcaagc caggaaataa tacatcttgt attttcccaa
     5341 tagttacttc ttgattcact aagctataaa ttgggtaggg ataatctaac tgtccaaaac
     5401 cacttatcag acttcccact agaaaagaaa agccacagat tccgataaac agcacagtta
     5461 catatcccac tccaactcca agagaggata ttgcaaatgt cacttttgaa acaggatata
     5521 agtgagctgt gtccagatga ttttgatatc tttctgcaaa tagttgtgtt agcataaaaa
     5581 taatcgcaac cacaaacaag cttgggatga taacctctaa aatccagaca atctgatcaa
     5641 tcccgtgggt cggaaactcc aaagtatgtg cttttatgtt caagggatac agggcttggt
     5701 aaatcttccg ttcgcggtca acccccattt ttaagccaga gctagcagtc gggtcatttg
     5761 atacaaattc ataattcttc tcttcatctt gccactgcag atagtaggct tctttccagc
     5821 gcccttcttt tagtaaagtt agaatttctg tctttcgcgt caaaagattt ttttgcacgt
     5881 ctaaattatt tttagcaaac tggtattcct ccgagctggt atcagacatt tgggagagtt
     5941 tctcttcatt ttcattgata gccctctcgt tggctgcaat gcgactttcc aacctgctct
     6001 ccaagctgtg tgagtttgca gtctgactat ttaaataaaa ggtaacaccg agtacagatg
     6061 caaataaaag taagataatc cagtttaaac gacttttgaa aacttttttc aataaaaata
     6121 gactaacatc tttcataaac taaacctctt ctatctgccc ctgatgaatg gttactactc
     6181 tatcgcagat atcaaccaac tcttccttat agtgggaact taaaagaacc agctgttctt
     6241 gtctatcgat ttgtgctagc ctatcaaaaa acttctgtcg ataatactcg tctaagccat
     6301 ttgtaatctc atccatgagc cagcatttgg cctgactgag aaaatacata gcaatcacca
     6361 agcgttgctt catccctaag gaatacttgc ggatgggaag actgatatag tcagccattt
     6421 cccagtaggc gatttcatct ctcaagttta ggtctgactt ccagatgttt tttatgagac
     6481 gaaggtagtc catcccactt aagtttccat ccagccattc aacgctctca taataaaaca
     6541 aagaaggagg aactgcgatg tgtccactac taaggggaag caacttgctc atagctcgga
     6601 atagtgtcgt ctttcccgag ccattgatag caagaaggcc ataaatccta ccctttttaa
     6661 aggtaaaatc cgcatcttgc aagatgactt gtcgcgtttt taaggtaaca tgagtaagat
     6721 ttaacatatc cagccctcct tttctcactc tttaaggatt aataacctcc agtatagtag
     6781 tttatgacct cataacgagc gtagttccag cctccgccaa ctttatactc agaatagctg
     6841 taataacgag accattccgg aatccaagca tactgatggt cgtgatagtt ggtactatat
     6901 tccaaaaccg tattccaatc atacttgtaa cttttagtgg ctgtcacagc agatacactg
     6961 gactgaagaa gaccaataga ttataaacta actaataaaa caacttttgc tgatttttaa
     7021 tgattttata tcctcaatat tgaatacgtt ttcattatac catttttatc attattatgc
     7081 aacaaatttt tagtttattt cactaatcta caacatttat ccttcctatc gaacactttc
     7141 gattttccaa ctatccaacc ccttaaaacg tatagctcct tgctggtcag ttcgataaac
     7201 tttgctattg ataccttcca gtcgtgtcaa tgtttcctga tgggggagtt tcattcgatt
     7261 gctctttcca actgagataa gagtaagctc tggtttgagt ttttctagaa aggctggact
     7321 tgatgatttt ttattgccat gttggctagc tttcaaaaca tttactttca agtctggata
     7381 gtgcttcagc aagtccttct ctcctttctc ctccaaattt cccgtgaaga gaaattgctt
     7441 atccaagaat ttcccataca gaactagggt gtcatcgtgt cctccatctc ccattttcct
     7501 tggagataga acttctaact gacttccaaa aatgggcaag ttctccccta ctgtcatact
     7561 acgcaccttt gtttgagtcg tctgtagttc tgccacaaat tccttctgtt tcagactgtc
     7621 ttttgatact agaatctccc ctacatggaa agccttggtc acctctgaca aatctccaac
     7681 attctccttg tccgtgttag tcaaaattag ctggtcaatc ttagctactc ctcgactttt
     7741 gagataggga atcaaggttc gctgggcatt gctggtcgtc atcttttctt gccatttttc
     7801 gattttctta taagattctg ccttaccacc tacatctatg agaatggttt tcccagttac
     7861 atcccgtagg aaaatacttt ctccttgccc cacatccagc atggtgattt cattttccag
     7921 tggatgcttg gtcaggagaa agagccctgt aatcaataaa ctcaatactg ttaatccttt
     7981 aatgtttttc ctcaaatcat agaccaaagc caaggaaatt aacaataaaa ttaaaaacca
     8041 tgcattgggt tgtccaaaga ccagaggtct acttgtcacc tgtgacacca agcgaataat
     8101 gccctccaac cattcaaaga taaagttcag ctgaatgact ggatagagaa aggaaaggac
     8161 aaataaaata gacaagagcg gtaagaaggt caagtcaaat agaaaggaaa agacaaaggt
     8221 caaaaggata gaccaaggtt gaaattccgc aaaatagaag gatagaatgg gcaatatgcc
     8281 caaggagatg actagacttt cactagtaac agccttgagc ccctcccctt ctttgctggt
     8341 catggtcagg ataaaagcat aagcgcagga caagactcct cctgctgtca agaaaaagtt
     8401 tggcatgaca ataaagagga caagcaccgt caaggcaaaa ttatccaagc ccttaacccc
     8461 atgttgagcc agtagctttt gcaagagact gcgaataacc gatgctgaaa atccagttag
     8521 tcccgcatag ataagggaaa agggataagt cagccatttc aacttttctt gggtcaagcc
     8581 caatcgcaag agaagtttct taaatccatt catgaaaaaa cctacctgca taccagatag
     8641 ggcaaagagg tggataattc ctagactgga ataaagctca ttcatctcct caaagtcggt
     8701 gtccagatgt cccagcaaga gtcctgtcat gtaattgcgc atagggtctg ggaagtgcat
     8761 cttaatccaa accacagcct ttcgacgtaa actggacagg ttttcaccta tatcccaact
     8821 gccaaccttt tggagtgact ggattctttt aatattgagt gtctggtaaa ttccctgagt
     8881 cttcagatag ccttggtagt caaagccacc aaaatttctc tgcccttctg gctccgaaag
     8941 cttcccttct agtcctatct catgaaggtc agttaaagct tgaaaggctt ctttctcctc
     9001 ctcggactgg agtttataat agacttggaa agcacgacca tcagacttac cacgaaagga
     9061 cagactgtca ccgttgacct taatagtgtc tggtaaaatc cgtacccttt caacagaatc
     9121 caccaaattt tgactcactt gactctgttg ccaagtttga aacagaaacc agaagccaaa
     9181 gactccacaa atcactagaa ctttacctgc tgatttccaa ggaaattgga taaagaggca
     9241 gactagcaga aaaacaaaac ccaacaaagc aaaataggat actgagaaaa tggcgtagta
     9301 aagccataat aacagaaaac tcaggtaaat taggggaata gagaaattct taatccactg
     9361 taacatagtc tttaagtttt tctatggtct tggcaccaat gccagagacc ttcttgagct
     9421 cgtctactga cttgaacttg ccatttgcct cacgatggtc aataatgtcc tgagctcgtt
     9481 tccctcccag tcccttgacc tgcttgagtt cttccagact ggccttgttg agattgacct
     9541 tcttttcctt gcttgttgaa gaagctgtcc ccgaaccagt ctgttgacta actgcttctt
     9601 ctcccttagt aggaacgtaa accagagcct catcactaac tttctgagct agattgagcg
     9661 acttgctgtc tgcttgctct gtcaagccac cagccttctg aacagcatca ttgactcgac
     9721 tacctacagg caagtcataa atccctggcg atttgacagc acctttgaca tctactgtga
     9781 ttagatcttg ttcaactggt tcttccttct cttccttgtt cacttccttt tcggatacca
     9841 aatccttgga aacagctgca acttcaacct gcaaattcgt ttcctttaca ggtgtttgtg
     9901 gagctggctt tagcaggaaa aatccgccta caagcaagcc cagaccagta cagatgacga
     9961 tgattttata ctctttgatt ttctcgataa ttgcttccat attttctcct ctcttagatt
    10021 attcgtaaga ggaagaaaaa acagtcgaaa aatttctttt caactgctta tttatttgca
    10081 aaatagtctt ccttggtcaa gacataatga actcttgtca cgattcggcc tttttcatgc
    10141 tggtccatac aagcatatgg ttctgcatgg gaaaaacgca tgcctgattt ctccatgacc
    10201 tttcctgacg cgggattagc cttatcgtga agggcagtca acttattcat ccctatcttc
    10261 tcaaaagcta gctcaatcac agcacgattg gcttctgtcg ttaatccttg attccaatac
    10321 tttttattgc taatgtagcc aatagctgcc ttcttaagaa cagaatcaat cttgtgcaag
    10381 tcaatggttc caataaactg accattgctt tttagttcta ttccccaacg tcccaaggga
    10441 ttaaccaaat agaactgagc aatgttattc ttggtttctt ccaagctttg attggttgga
    10501 aaagtgtaac gtgtattacc cttgtccgag gcatagtcaa acattgcttc cgcatcatcc
    10561 aaagttacag gtctaagcaa taaacgctcc gtttctatag acggatactg ggcaagtttt
    10621 acaaaaattg attccatact tttccctcca ttagagcttg attttcacta gtctagcata
    10681 aaaaaatttg gatgacaagt ttttcttgat ttttgaagcg gtttcatata caatgaaacc
    10741 gtcacatttt tgatttatga actggaatgt gacaaccaaa acaagaccgt caattgaaag
    10801 gtaggttatc tcaatgttaa tcggaatccc aaaagaaatt aaaaataacg aaaaccgtgt
    10861 cgccctcaca cctgcaggtg ttcatagctt agttagtcgt ggtcatcgtg tccttatcga
    10921 aacaaatgct ggtctcggtt ctggctttac tgatgctgac tatcaaaagc aaggagctga
    10981 gattgtcgct actgctggtg aagcttgggc agcagagttg gttgtgaaag taaaagaacc
    11041 tttaagttct gaatacggtt acttgcgcga cgatcttctt ctcttcacct acttgcacat
    11101 ggccgctgct ccagaattag cagatgctat gttagcagca aaaacaacag gaattgccta
    11161 tgaaactgtt cgtgacaatc aaggacaact accgctcctc gttcctatga gtgaggttgc
    11221 aggtcgtatg gctgtttaaa tcggagctca cttccttact aagcaagctg gtggctctgg
    11281 tgttctacct ggtggtgtac caggtgttcc aaaaggaaaa gtaactatca tcggtgatgg
    11341 tgtcgtcggt acacatgctg cccgcatcgc ccttggtctt ggtgctcaag tgactatttt
    11401 agatattagt gccaagcgtc tctcagttct agaagaagtc tttggaagtc aaattcaaac
    11461 tcttatatct aattcattca acattgaagc aagtgtgaga gatgctgatg tggtgattgg
    11521 agccattctc atccctggtg caaaagcacc ggaattggtg acagatgaga tggtcaaaca
    11581 aatgcgtcca ggctctgtat cgttgacgtt gctgttgacc aaggtggcgt tatcgaaaca
    11641 gctgaccgtg tgacaacgca cgatgaaccc gtctatgaaa aacacggtgt tctccactat
    11701 gccgttgcca atatccctgg tgcggttgct cgcacttcaa ccatcgccct aaccaatgtc
    11761 actcttcctt atatcgaagc tttggctggc aaaggattcg cacaagcaat ctctgaagat
    11821 gaaggcttgc gtcaaggtgt gaccacttat caaggttact taactagcct accagttgct
    11881 caaggactta atcgtgacta cactgatatc aatgatttag tataaatttt gaaaagaaaa
    11941 gggtgacttc gcaagtccta cccactgtgc tttgtgtcat cagctattac atcgttggtt
    12001 tattgtactg tatactttgc aactggagac tttcgttcca gactcaattg tgcataagaa
    12061 actctaaatt gaataaaatc aacagagttt cgcccaacca cttcgtcttg taatgacaat
    12121 tatataaacc aaaggaagct gagctcttta gtcccagctt ctttttatat ataaaatttt
    12181 acccgtgcaa agacagggcc ttagcagact tcttttttac ttcgttcacc cttgcttttt
    12241 ctttttaggt ttgggcgttg gcagttggtt atacatagct aaaatcaggt cttatagaaa
    12301 catcttatta tcaagttctt ccactcaaat catttctttg gcacctttgt atggaaactc
    12361 aaaagaagat tggtcaatct tatctaagac tgcttgcacg ggtttaacta aaagcgatcg
    12421 tcataaatgc cgccaataat cttgccgcgg aagtaaagaa tatactcccc catcatggaa
    12481 cggtaagtca catcatctaa tcctgataat tgttccaaaa caaattccaa atagttctta
    12541 cttgatgcca tttctaatct tctaggctct gttcaacgat aacaaccgta tagagttctt
    12601 gcttaacctc gcatccaatt gatttaaagc cctgcttttc ccaaaaatgc tgagattgcg
    12661 gatttccctt aacataagcc aaacgtgcct ttcgaaagtt cttagcaaaa taagctagtg
    12721 cttctgtcac aatatgacta ccaatccctt tcctctgata ggcttgatca accataaaca
    12781 aaccaataaa aacagtctcc tcatcaggat atgcatagac aaaatccata acagccacaa
    12841 ggtcaaatcc attccaaaat ccaacaaaaa acttatcagc cttagcttta ccttcaggta
    12901 gacaaagcat gtcctctttt acagttgcaa aatttggctc tggtggacaa tgctgaaaat
    12961 acagaggatt actttcatat aaagataaaa tacttggaat atccttttca gttagtatcc
    13021 tacaactgta atacttagat agttggtcaa tcatcttttc aaattcctac tttcttgtgc
    13081 cctgtgatta tgacacagga agatgcactg atcgtcatca gccacataaa agttctttcc
    13141 atcgtgccta atcgttgtct caaacctttg gataaaacct ttagcctata caactggatt
    13201 ttcctctctc aaaagtatat tcttttgcag gcgaacttcc tcaaaatcag tcgtgtgcaa
    13261 cttcagtaga atattcatag gctcggataa tctgagcgac aacaggatgg cgaaccacat
    13321 ccttggctga aaaatgaaca aagtcaatct gatggatgtt cttgagtttc tcttgagcat
    13381 caatcaaacc ggacttgaca ttacgtggca ggtcaatctg actaatatct ccattgacaa
    13441 tcatcttaga atgaaaacct aaacgagtca agaacatctt catctgcatg atggtcgtat
    13501 tttgcgcctc atcgagaatg acaaaggcat catccaaggt ccgtccacgc atataggcaa
    13561 ggggcgcaat ctcgataatt tcacgctcca tgagtcgagt tgtttggtct ttccccagaa
    13621 tctgatacaa ggcatcataa acaggtctaa ggtaaggatc taccttctcc ttaagatcac
    13681 ccggaagaaa acctagactc tctcctgctt ccaccgctgg acgtgtcaag ataatccgct
    13741 tgacttgccc acgtttaagg gcagtcactg ccaaagtaac tgcaagaaag gtcttccccg
    13801 tccctgcagg cccaattcca aaggtcacat catgctgttt gacactgtcc acataaagtt
    13861 tttgacctaa ggttttgacg cggatcggtt tcccagtatt atctttgata atttcttctt
    13921 cgtaaagggc gacaaactta tcaatttcat cgtttttgac catgctaatt gcagtcacca
    13981 catctggcgt accaacggtc atcccacggt tcaccaagac catgagagct tgaataacct
    14041 gacgggcttc ctcacaagca gactcttctc ccaaaacctg gacaatctcc gtacgagcat
    14101 gaatcaccac atccagctct tcttccatca aacgaagatg acgctcattg gaaccaaaaa
    14161 gatgaaacag gtcatctgga tgactcagtt gaatgtctat tgaatgttcc ttcaaataaa
    14221 gaacctctct aatcctttta tttcttttta ttatagcaga gggatggaga aattactagc
    14281 ccaaacccaa tgaataaatg ctagtgttct agatattcct gccaaatgct gtcaaaatct
    14341 cctaggttaa aagagaaact ggcatgctcc tccaaaaagc gactgacctc atcaaaatca
    14401 tctgtatgtt ttggaaaagc tgcctcttca aaagcgagat ctgccaaaat tgctttggga
    14461 ctgttacttt taggattgcg ctcggtcatg agccaagtgt aaaatgattt tctcataagc
    14521 ctccctaaat caactctgta ccaaactggt cctgcttgat tttaccagcc ttcataagac
    14581 cacctaaagc tttcttgaac tgacctttag aaatgccaaa ggttgccttg atgtcgtctg
    14641 gagatgactt gtcatttaag gtcatgaaac cgccattgct ttccaaataa gtcaaaatca
    14701 tctgagcatc gttttccaac atttcaaagg agcgtggttt gagggagagg ttcaaagtgc
    14761 ggtccacttc acggaaacca ataacgcgcg catctaatac ttgccccaaa cgtggctctg
    14821 cgtaacgctc gctaggatga ataaaaccaa gcatattatt ttctggtagg taaacaaaag
    14881 ttcctgacag cttgagacgg taaacaatgg ctggccagtt ttggttctgc atgttgttgt
    14941 aggcaggacg agcgagacgt tggaagtctt cttgataagc caagaggccc cagatacggt
    15001 ctttcttatc cacttcaaga cggatgtaga gttggtcgcc cttcttaggc cagagttcct
    15061 tgagctcagg gagaatatcg agtgacacaa cgatttcctt gtcaggaagg cctgtatcca
    15121 caaagacacc caagtcctta cgaacctctg tgacacgtcc ccaaccaaat tggtcctgag
    15181 tggcagtcac ttctaaggtt gtcaggcgga gtttttgctt catatccgtg tatgcaaaac
    15241 ctttgaccgt atcccctact gtatgttggc cctcttcctt agcaagagca taggtttgac
    15301 catccttttg cacaaagtaa aaacggtcat tttcatcgat gatcagtcca acgataaaac
    15361 ttgcaagatt tgtattcata tttccttctt tcgaataaaa ctcagccagc aatgccaact
    15421 gagtttttct gtttattttt agacttccaa aagttctttc tctttgttag cagtcatgtc
    15481 gtcgatgtgt ttaacagcat cgtctgttac tttttgaata tctttttcaa gagtcttcaa
    15541 ttcgtcttca gtgatttctt ttgctttttc ttgtttctta gcttcgtcca tagcatcgcg
    15601 acggatattg cggacagcca ctttagcatt ttcgccgacc ttcttcactt ctttagcaag
    15661 gtcacgacga gtttcttctg taagagctgg gataaccaag cgaatcacag aaccgtcatt
    15721 agccggtgtg ataccaagat cagaagcgtt caaggcacgt tcgatgtctt tcaatgaaga
    15781 cttgtcaaat ggtgttacca acaaaacacg cgcttctgga atcgtaattg aagcgatttg
    15841 gttaagagga gtttcgactc catagtattc tacatgtaca cggtcaagca agcttgcatt
    15901 ggcacgacca gcacggatac caccaaattc acgagcaagt gattggtgag actgggtcat
    15961 tctctcttta gctttttcaa taattacgtt agccatattc tttcttattc cttttcttcg
    16021 atattatttg aaactgttgt tccgatattt tcaccaaata cgacacgttt gatgttgcct
    16081 gattggttca tgttgaagac aaccaagtca atgtcgttgt ccattgagag ggttgaggct
    16141 gttgagtcca tgatacgaag acctttgttg ataacatcac ggtgggtcaa ttcttcaaac
    16201 ttaacggctg tcttgtcctt cttaggatcg gcattgtaca caccatcgac gccattttta
    16261 gccatgagga tggcatctgc ttcgatttca gctgcacgaa gggccgctgt tgtatctgtc
    16321 gagaagtatg gtgaaccaat tccagcacca aagataacga tacggccttt ttcaaggtga
    16381 cgaagggcac gtccacggac ataaggctct gccacttgtt gcatagcaat agctgtttgt
    16441 acacgcgtat caaccccaac ttgttgcaat gaatctgcca tcacaagagc attcataaca
    16501 gtcccaagca ttccagtgta atctgcctga acacggtcca tacctgcttc tgctgcaggt
    16561 tctccacgcc agagatttcc tccaccaata acaagggcaa tttcgatacc taagctatga
    16621 acttcttgaa tctcttttgc gattgtttga actgtttgga tatcaatccc tacgccacgt
    16681 tcaccggcaa gggcttcacc tgataacttg attaaaatac gtttatactt gggattcgcc
    16741 attttcactc tccttctttc atcctaccta ttttatcaca atttctaaga tttttatagt
    16801 atcatgaaca attctttcaa aaaaattaga cagtcaaaaa ttcctctaag tcggcaaggg
    16861 cacgctctgc aattttttca taacgagcct tcttatcacg gatacgctcg ccttccaact
    16921 ccttgatgat cccaaaattg acattcattg gttggaaatg tttgctgtcg gcatgggtaa
    16981 tgtaatgagc taagcttcca atcgctgtcg tctcggggaa aataacctcg ctttcttcct
    17041 tgaagagacg agctgcgtta attcccgcaa ctaagcccga agccgccgac tcaacatagc
    17101 cttccacccc cgtcatctga ccagcaaaga agagatttgg ttgtttcttg gaacggtaag
    17161 tctgctcaag aagatttggt gaatccatgt aagaattgcg atgcatgaca ccataacgga
    17221 caaactccgc attttcaaga cccggaatca tttggaagac acgcttttgt tctccccatt
    17281 tgaggtgggt ctggaaacca acaatattgt ataggctacc agctgcatta tcctgacgaa
    17341 gttgcacaac cgcataaggt gttttaaatt ctccatcacg aggtcctgtg tagtcgtccg
    17401 gatactcaag accgactggc ttcatagggc cataaagcat agttttaatg ccacgtttgg
    17461 ccataacttc gattggcata catccttcaa agtacttttc tttttcaaaa gaattgagcg
    17521 gtgcttcttc cgcattgacc aaggcttcat ggaaatccat aaactcttgc ttggtcattg
    17581 gagcattgag ataggctgct tctcccttat cataacgaga tttgagatag accttactca
    17641 tatcgatagt gttgacatcg ataataggcg ctgctgcatc gtagaaatag aagccatcgc
    17701 cattattaag ggcatgaatc ttttcagcca gggcatcgct agtcaaggga ccagtcgcca
    17761 caactgtaat aacatctgtt ggcaattctg taatttcatc acgcaccact tcaatcaagg
    17821 ggtggttgac cactttttcg gtcaccattt gagagaaacc atcacgatcc accgcaaggg
    17881 ctccaccggc aggaacacgt gtagcctcag cagattccaa gataacagaa cccaagcgac
    17941 gcatttcttc cttgagaaga ccaactgcat ttatcaaagc atccccacgc aaagaattgg
    18001 aacaaaccaa ctcagcaaaa ttgtctgttt tatgctgggg tgtagacttg acaccacgca
    18061 tttcatatag tttaactgga ataccacgct ctgcgatttg gtaagctgct tcagaacctg
    18121 ccaaaccagc accgataaca ttgatataag attgagacac gacactaata cctctttggg
    18181 agtgtgaagt taagattcac attgaaaaag ccaatcagac ttacaagctt tcgagtttct
    18241 tggctcaggc tgaaaaagtc cacagggctt tttcactccc acaaatcttt ctattttttc
    18301 ttctactagt ataacaaaaa aagggaagaa ggcaaacttc cctgtttagt cattttcttg
    18361 atgtaaagag atagtgagta ttccagttaa gaatcaatta tatgctactc tataaaatct
    18421 tttccacata acggatcgat agggactgtt attctatctc ttgctataac cgtattatct
    18481 aaaacagcat aacattcaac atagtgatct cctttaaact gtgaatcttc gtgatatttt
    18541 attttacctg aaaaaatagc accacgctca caatttcttc taatagcctc agcttcaata
    18601 tttcttactt tccaatagac ttcctgcgaa acaaaatatg gtatagtagt tctatgaat
//
LOCUS       DBERPV010000035        18105 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.35, whole genome shotgun sequence.
ACCESSION   DBERPV010000035 DBERPV010000000
VERSION     DBERPV010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 18105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18105
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.35"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(136..1071)
                     /gene="birA"
                     /locus_tag="ACL8C7_001649"
     CDS             complement(136..1071)
                     /gene="birA"
                     /locus_tag="ACL8C7_001649"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/biotin operon repressor BirA"
                     /protein_id="HGS1395805.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEINSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1068..1928)
                     /locus_tag="ACL8C7_001650"
     CDS             complement(1068..1928)
                     /locus_tag="ACL8C7_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGS1395806.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIS
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQSPSHTRKEYS
                     QYQLVRKATL"
     gene            2036..4198
                     /locus_tag="ACL8C7_001651"
     CDS             2036..4198
                     /locus_tag="ACL8C7_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HGS1395807.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIILSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4290..5548
                     /locus_tag="ACL8C7_001652"
                     /pseudo
     CDS             4290..5548
                     /locus_tag="ACL8C7_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            5562..6428
                     /locus_tag="ACL8C7_001653"
     CDS             5562..6428
                     /locus_tag="ACL8C7_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS1395808.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRSWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            6442..7275
                     /locus_tag="ACL8C7_001654"
     CDS             6442..7275
                     /locus_tag="ACL8C7_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS1395809.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7633..9075
                     /gene="gtfA"
                     /locus_tag="ACL8C7_001655"
     CDS             7633..9075
                     /gene="gtfA"
                     /locus_tag="ACL8C7_001655"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HGS1395810.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKALFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVVEIDLQNQTYRVIENGVEVSF"
     gene            9213..10406
                     /locus_tag="ACL8C7_001656"
     CDS             9213..10406
                     /locus_tag="ACL8C7_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HGS1395811.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMNSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11091..13070
                     /locus_tag="ACL8C7_001657"
     CDS             11091..13070
                     /locus_tag="ACL8C7_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS1395812.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KAVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13137..14633
                     /locus_tag="ACL8C7_001658"
     CDS             13137..14633
                     /locus_tag="ACL8C7_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1395813.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPAAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14633..15559
                     /gene="oppC"
                     /locus_tag="ACL8C7_001659"
     CDS             14633..15559
                     /gene="oppC"
                     /locus_tag="ACL8C7_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppC"
                     /protein_id="HGS1395814.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15568..16635
                     /locus_tag="ACL8C7_001660"
     CDS             15568..16635
                     /locus_tag="ACL8C7_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1395815.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSKTHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16646..17572
                     /locus_tag="ACL8C7_001661"
     CDS             16646..17572
                     /locus_tag="ACL8C7_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS1395816.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            complement(17647..>18105)
                     /locus_tag="ACL8C7_001662"
     CDS             complement(17647..>18105)
                     /locus_tag="ACL8C7_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000530077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS1395817.1"
                     /translation="RYWKLIQQDSRKLSDKRFYRPTFRMHLTNKEILDKILSYSEDLK
                     HHYQIYQLLLFHFQNKDPEKFFGLIEDNLKQVHPIFQTVFKTFLKDKEKIINALQLHY
                     SNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
BASE COUNT         5329 a         3208 c         3805 g         5763 t
ORIGIN      
        1 taggctccat aatatctata ggggatttac ccactacaaa tattatagag acaataaaac
       61 ttcagatccg taaaacttaa ttgaattact aatctgaagt tatttttata tcgtttatat
      121 tataattgtg ttattttact tccaactatt gagagaaatt tcgccactat ttagccagat
      181 ttcttttccg ttatcacatt gaactaaaag ttttccattt tctgagatgt ctttagcaag
      241 tcccttgtag tctttttgct ctagtgtgaa agtgacttct tttcctagaa tgaatgactg
      301 ttttttgtat aggtataata gctcttctgc tggtgtttcg aagaaagcac gccagatttc
      361 tatgatcaat tcattccttg ttataggagc tgtagcttta aataagctgg cagctttttc
      421 ttttaattcc tgagggaagt ctttaatagt gaaattgata cctactccaa taatgatatc
      481 tgtgactaag ccagtttcta cagaggtcat tgcttcagta aggattcctc caattttatg
      541 attgtttaga tagatatcat tgacccattt tatatcgaca tctattaaag ttaggttctt
      601 aatggctttg tagacagctc cagctacaag tagtgtgtag gatggtaatt tgtcataggg
      661 gagatttggt ttaagatgga gtgtcatata aattccacct tgtggtgagt agaaggaacg
      721 ttgaaaacgg cctcggcctg ctgtttgata ggaagctaga tagagagtat ttgcttcatg
      781 gcctaaatca attgcttctt ttgcatctag ttgtgttgat tttgtttcgg gtttaaagct
      841 gactttaatt ggaagatttt cttctagaat ctctggaaga ataaggtcac cattcattag
      901 tttatatcct ctatttttga tactattaat ttcaatgcct tcttgttcta gtcgcttgat
      961 agctttccaa attgatgttc ggcttaggga tagtttttct gcgatttttt ctccgctgat
     1021 atagtcggtt tctttagata ggatttggta gacagcttgg taggatttca taatgttgcc
     1081 tttctcacta gttggtattg agagtattct tttcttgtat gacttggaga ctgattaaag
     1141 tattgtttat aagctttcga aaaatggagt ggatctgaaa aacctaccga gtatgcaatt
     1201 accttgatgg actcttgggt attttcgaga agttgtctag ctcggtgcat tcgaacgtag
     1261 agtaggtatt ctttgggtga taaggtatta aattctttga atacgcttga taagtagctt
     1321 ctgtgaacgg atagttcttt tgctaaatct tgaattgtaa gtgattgagg atagtggcta
     1381 tcaattaatc gtttgcattc aagatagagt tggtgggttg atgaaatatt cttttttttc
     1441 tgattgggag caatagttcc cagatgaaac atcagttcat gaagttgtcc catgatatgg
     1501 agttgagcta attcacttga ttttgtaatc tgagcgaagc ggacaatgtc tgagatgagt
     1561 tttgcagtag tctgggtatg acaagtttca gattggatga gataggattg atcagaaatt
     1621 tgagaaagag caaaataatc aggggatttc cctccagtga ttcctaacca gtagtaggcc
     1681 caaggttctt tactatctgc ttgataaaag gttagttcct ctggttttaa tagaaagaaa
     1741 tctccttctt ttaaatcaac aattttaccc ttgtaatgaa attttccttg tcctttacta
     1801 atgtaatgta ggacgtatgt atcacgaatg gctggaccaa aagagtaatt aggtgtgcat
     1861 tcctcatatc cataaaagct tagggcaagg tcaattgttc cagtctggta ttctgaaaaa
     1921 actagcatgt gctacctcct acctaacatt ttaccatatt cttgagacat ttttctattt
     1981 tggaaagcga tttcaggtga taaaatataa tcaataaagt gatgaggtga agtaaatggg
     2041 agttaggata gagaataatc tattttatgt tgagagtaaa aatctaagtt tgattattga
     2101 aaatcgaaat ggctacttac ttttgaaaca tttaggaaag actattaaga actataaagg
     2161 ttccaatagt gtttatgaac gagaccatgc cttttcagga aatccaacgg ctactaatcg
     2221 aacctttagt ttagatactc agcgacagat ttttggacaa catggcttag gagattttag
     2281 gaaaccaact atacaggttc agcatagtgt aactgaagta acagactttc gatttgtaga
     2341 agcaaagatt ttaaaaggtc agaatggtcc acagggctta ccttctccac atagcatgga
     2401 cgatacagag actcttgtct taatgttaga agattctaag gctcaactta gtctgacttt
     2461 gtattatact acttttaata atgatgcgac tattgctagc tacagtaaat tagataataa
     2521 tagtaatcag gaagttgtca tccataaaga tttttctttt atggctgatt ttccagctgc
     2581 agattacgaa atagtaactc tgcagggtgc ttatgctcgt gaaaagactg ttagacgtca
     2641 acaggtagaa caaggaatct tttcgattag ttcaaaccga ggtgcttctg gtcatgctca
     2701 aacaccagct cttctactat gcgaacaagg agtcacagag gatgctggga atgtgtttgc
     2761 tattcaacta atgtatagtg gcaactttga agcttttgtt caaaaaaatc aattgaatga
     2821 agttcgggtg gctattggca ttaatccaga aaacttttct tggaagttag cccctgagga
     2881 atactttgaa acaccggtag ctttagtgac tcattcagat cagggattaa ctggtattag
     2941 tcatgaaagt cagaattttg tactgaagca cattattcta agtgaatttt ctaaaaaaga
     3001 acgtccaatt ctaatcaata actgggaagc tacttacttt gactttcaga gagaaaaact
     3061 gttagagtta gcagatgaag ctaagaaagt tggcattgaa ctttttgtat tagatgatgg
     3121 ttggtttggc aatcgttttg atgataatcg tgctttaggt gattgggttg ttaatgagga
     3181 aaaactgggt ggaagtctag aaagtctgat ttcagctatc catgaaagag gtttgcagtt
     3241 tggactttgg ttagaacccg aaatgatttc tgtagatagt gatttgtatc gtcaacatcc
     3301 tgactgggct attcaggttc ctgattatga gcatacttat tctcggaatc aattagtact
     3361 taatcttgcc aatcctcagg tagtagaata cttgaaaagt gtcttagatc aactcctatc
     3421 ttatcatgag attgattaca ttaaatggga tatgaaccgc aatatcacta agctagggaa
     3481 tggattaact tatctagaga cacagatgca atctcatcag tacatgctgg gactttacga
     3541 actcgtttct tatctgacag agaagcacag ccatattctc tttgagtcct gctctggtgg
     3601 tggtggacga aatgatcttg gtatgatacg ctatttccca caagtctggg ctagtgataa
     3661 tactgatgcc attgcacgtt taccaattca atacggttca tcctatctct atccaaccat
     3721 ttctatgggg gctcatgtgt cagcagtacc gaatcatcag atgggacgaa tgacaccatt
     3781 agaaacacgt ggccatgtag caatgatggg aaatttgggc tatgagcttg atttgacaaa
     3841 tttatcagat gaagagaaag ctacgattgc taatcaggtg aacttgtata aagaattacg
     3901 accagtagtt cagttaggac agcagtatag actaattaat cctgatactg catccaatga
     3961 agcagctgta caatttaatt acggaaatca aacgattgta acctacgttc gcgttttatc
     4021 tgttgtagag accatggaaa caactttaaa attaaaagat ttggatgaag agggactata
     4081 taaattacag gaaaatggcg aagtttactc aggtgcagaa ctaatgtatg cgggcttaac
     4141 tgttatctta tcccaaggag attttttgag tagacagtat atttttagaa aactatgata
     4201 tgtactgacc ccaaaagtta gatttattct gtctaacttt tggggtgcag ttcaataagg
     4261 gtgtataaat ttataaagga ggctttctaa tggaatggta taaaaaatcg gacttcttgc
     4321 aactacaggt ttagctttgt ttgggctcgg cgcttgctcc aactatggta aatctgcgga
     4381 tggcacagtg accatcgagt atttcaacca gaaaaaagaa atgaccaaaa ccttggaaga
     4441 aatcactcgt gattttgaga aggaaaaccc taagatcaag gtcaaagtcg tcaatgtacc
     4501 aaatgctggt gaagtattga agacacgcgt tctcgcagga gatgtgcctg atgtggtcaa
     4561 tatttaccca cagtccatcg aactgcaaga atgggcaaaa gcaggtgttt ttgaagattt
     4621 gagcaacaaa gactacctga aacgcgtgaa aaatggctac gctgaaaaat atgctgtaaa
     4681 cgaaaaagtt tacaacgttc cttttacagc taatgcttat ggaatttact acaacaaaga
     4741 taaattcgaa gaactgggct tgaaggttcc tgaaacctgg gatgaatttg aacagttagt
     4801 caaagatatc gttgctaaag gacaaacacc atttggaatt gcaggtgcag atgcttggac
     4861 actcaatggt tacaatcaat tagcctttgc gacagcaaca ggtggaggaa aagaagcaaa
     4921 tcaatacctt cgttattctc aaccaaatgc cattaaattg tcggatccga ttatgaaaga
     4981 tgatatcaag gtcatggaca tccttcgcat caatggctct aagcaaaaga actgggaagg
     5041 tgctggctat accgatgtta tcggagcctt cgcacgtggg gatgtcctca tgacaccaaa
     5101 tgggtcttgg gcgatcacag cgattaatga acaaaaaccg aactttaaga ttgggacctt
     5161 catgattcca ggaaaagaaa aaggacaaag cttaaccgtt ggtgcgggag acttggcatg
     5221 gtctatctca gccaccacca aacatccaaa agaagccaat gcctttgtgg aatatatgac
     5281 ccgtccagaa gtcatgcaaa aatactacga tgtggacgga tctccaacag cgatcgaagg
     5341 ggtcaaacaa gcaggagaag attcaccgct tgctggtatg accgaatatg cctttacgga
     5401 tcgtcacttg gtctggttgc aacaatactg gaccagtgaa gcagacttcc ataccttgac
     5461 catgaactat gtcttgaccg gtgataaaga aggcatggtc aatgatttga atgccttctt
     5521 taacccgatg aaagcggatg tggattagga gtagagagac tatgaaaaaa gtattacaaa
     5581 aatattgggc atgggctttt gtggtcatcc ccctcttgtt acaagcaatt ttcttctatg
     5641 tgccgatgtt tcaaggagcc ttttacagtt ttaccaactg gacaggattg acttataact
     5701 acaaatttgt cggcttaaac aactttaagc tcctcttcat ggatccaaaa ttcatgaatg
     5761 cgattggctt taccgcaatc attacgattg ccatggtggt tggtgagatt gcactcggga
     5821 tcttcattgc gcgtgtcttg aactctaaaa tcaaaggcca aaccttcttc cgttcttggt
     5881 tcttcttccc agctgtttta tctggtttga cagtggcttt gatcttcaag caagtcttca
     5941 actacggtct tccagcgatt gggaatgccc ttcatattga atttctccaa accagtcttt
     6001 tagggactaa gtggggagca atctttgcgg ctgtctttgt ccttctttgg caaggggtgg
     6061 ctatgcccat catcatcttc ctagctggtt tgcaatctat tccaactgag attacagagg
     6121 cagcaaggat tgatggtgcg actagcaagc aagttttctg gaacattgaa ttgccttact
     6181 tgctaccaag tgtctctata gtctttatcc tagccttaaa aggtgggctg actgcctttg
     6241 accaagtctt tgccatgacc ggtggtggtc caaacaatgc cacaacctca cttgggctct
     6301 tggtttataa ctatgccttt aaaaacaacc aattcggtta tgccaatgcc attgccgtaa
     6361 tcttgttctt cttaattgta gtgatttcga tcatccaatt gagagtatct aagaaatttg
     6421 aaatttaaga ggagaagcat gatgaaacaa gatgaaagaa aagccctgat tggcaaatac
     6481 attctattga ttctaggatc ggttctgatt ttagtgccgc tccttgctac cctctttagt
     6541 tccttcaaac ccactaagga tattgtagat aatttctttg gctttccaac caacttcaca
     6601 tgggacaact ttagccgtct cttagctgat gggattggag gctattattg gaactctgtc
     6661 gtcatcactg tcttgtcttt acttgcagta atgatcttta tccctatggc agcctactcc
     6721 atcgctcgca atatgagtaa aagaaaagcc tttaccatca tgtataccct cttaatcctc
     6781 ggaatcttcg tacctttcca agtcatcatg attccgatta cggttatgat gagtaaactc
     6841 ggtttggcta atacctttgg tttgatcttg ctctacttga cctatgcgat tccacagacc
     6901 ctctttctct atgttggcta tatcaaaatc tcgattccag aaagtctgga tgaagcagca
     6961 gagatcgatg gggctaatca atttacaacc tatttccgca tcatcttccc aatgatgaaa
     7021 ccgatgcatg cgacaaccat gatcatcaat gccctttggt tctggaatga cttcatgttg
     7081 ccactccttg tcttgaaccg ggattccaaa atgtggactc tgcctttgtt ccaatacaac
     7141 tacgcaggcc aatatttcaa cgactacgga ccaagctttg cctcttacgt ggtcggcatt
     7201 atcagtatca ccattgtcta tctcttcttc caacgccata tcatttcagg aatgagcaac
     7261 ggggcagtga agtaatactc aatgaaaatc aaagagcaaa ctaggaagct agccgcaggt
     7321 tgctcaaaac actgttttga ggttgtggat gaaactgacg aagtcagtaa ccatacctac
     7381 ggcaaggtga agctgacgtg gtttgaagag attttcgaag agtataagaa gagctcatgg
     7441 aatctatagt ctttgacaca gaggaagagt tcagcttgtt gataattcta tgtagaaaac
     7501 aagaaagtag tactttgttt atcacagtct atattagtac gagtttgatg ataaatagag
     7561 atttaaaatg aattttattt atgaagccag atcatatgag acttggcttc aattagaaaa
     7621 aggagagtaa tgatgccaat tcaaaataaa accatgttga ttacctattc tgatagcctt
     7681 ggaaataatc ttaaagactt atatgataat ttggaagagc attttggaga tgctattgga
     7741 ggagttcacc ttttaccatt tttcccatca acaggtgatc gtggatttgc gccagttgac
     7801 tacgacgaag tggactcagc ttttggtgat tgggaggatg ttaagcgttt aggtgagaga
     7861 tattatctta tgtttgattt tatgattaat catatttctc gtcaatccaa gtattataag
     7921 gactatcaag aaaaacatga agccagtgaa tttaaagctc tctttttaaa ctgggataag
     7981 ttttggccag aaaaccgtcc gacacagtct gatgtagatt taatttacaa gcgtaaggat
     8041 cgtgcaccaa agcaagagat tgtgtttgaa gatggttcag tggaacattt gtggaatacc
     8101 tttggtgagg agcagattga tcttgatgtg accaaagaag taactatgga atttatccgt
     8161 aagaccattc agcacttggc aagtaatggg tgtgatttga ttcgtctaga tgcctttgct
     8221 tatgcagtga agaaattgga tactaatgat ttctttgtgg aaccagatat ttgggattta
     8281 ttggacaaag ttcgagatat cgctgctgag tatgggacag agcttttacc tgagattcat
     8341 gaacactatt cgattcagtt taaaatagca gaccatgatt actatgttta tgattttgct
     8401 cttccaatgg tgacacttta tactctttac agttccagaa cagagcgttt ggctaagtgg
     8461 ttaaagatga gcccgatgaa gcaatttacg acgctagata cccatgatgg gattggagta
     8521 gtagatgtca aggatatcct gaccgatgag gagattgact atgcttcaaa tgaactctat
     8581 aaggttggag ccaatgtcaa acgtaagtac tctagtgccg agtataacaa cttagatatc
     8641 taccaaatca attcaaccta ctattcagcg cttggagatg atgatgtcaa gtattttctc
     8701 gctcgtctaa ttcaagcttt tgccccaggt attcctcagg tttactatgt gggtctatta
     8761 gcaggcaaga atgacttgaa attattagaa gaaactaaag aaggtcgaaa tattaatcgt
     8821 cattactata gcaacgagga aatagcaaaa gaagtgcaac gacctgttgt gaaggccctt
     8881 ctcaatctat tttctttccg taaccgttca gaagcctttg atctagaggg gactactgag
     8941 atagagacac caacagctca cagcattgta atcaaacgtc aaaataaaga taagtccgta
     9001 acagcagtag tagaaattga tttgcaaaat cagacttatc gggtaattga gaatggagtt
     9061 gaagtatcat tttgaagcct tgatatggtg gataaaatag ggtttttatt ttggaaaacg
     9121 tttcctttgt tttcaaattg ctaaaaaagt ggtacaatat aggatagctt actattatct
     9181 gaatcagctg atttggagag aaaggattca ttttgaaatc aataggcttt attgaaaagc
     9241 tgaaggggtt gtctagtaaa gagctgattt tattgggaat tatcctgagt atctttttac
     9301 ccttttatct ttttgtagtt gtactctgtt tatatattat cagtttgatt tttacaggag
     9361 acatgaaaag tattcttcag aaaatggggg agcatccgat gctgcttctt tttcttagct
     9421 atagtactgt tatatccatt cttgcacaaa attggatggg tcttgtggct tcagtaggaa
     9481 tgtttctatt tactattttc tttttgcact atcagtcgat tttatcccat aaattctttc
     9541 gattgatttt gcagtttgtc ttgtttggta gtgtcttgtc agctgctttt gccagtttag
     9601 aacatttcca aattgtgaag aaatttaact atgcttttct ttcacccaat atgcaggtgt
     9661 ggcatcagaa ccgggcagaa gtgaccttct ttaatcctaa ttattatgga attatttgtt
     9721 gtttctgtat tatgattgct ttctatctgt ttacaacgac caagttgaat tggttgaaag
     9781 tattctgtgt gattgcaggc tttgttaatc tctttggttt gaactttact cagaatcgaa
     9841 ctgcctttcc tgctattatc gctggagcaa ttatctatct ctttacgact attaaaaact
     9901 ggaaggcctt ttggcttagt attggggtct tcgcgattgg tttgagtttc ctcttttcta
     9961 gtgatttggg agttcgaatg ggtactttag actcttctat ggaagaacgc atttctatct
    10021 gggatgctgg gatggccttg tttaagcaaa atcctttttg gggtgaaggg ccattgacct
    10081 atatgaactc ttatcctcgg atacatgctc cttatcatga acatgcccac agtctttata
    10141 ttgatacgat tctgagttac ggaattgtgg ggactatttt attagttttg tcttctgttg
    10201 ctcctgttcg cttgatgatg gatatgagtc aggagtcggg gaaacgtccg attatcggcc
    10261 tttatctatc tttccttaca gtggttgctg tgcacggaat ttttgacttg gctctcttct
    10321 ggattcagtc aggctttatt ttcttgctag ttatgtgcag tattccattg gagcatcgaa
    10381 tgttggtatc ggacatgacg gattaagttt tataagtttg aaatcttcta ccttgggtag
    10441 gagatttttt atacgatggg catgtcgtgc atctgaggtg taagtcctct gtagggctcc
    10501 actaccggtg aatacaatag cgctccccaa gcctgactat cgtgaggtag cggattaaaa
    10561 tggtctgggg atagatcgtt ttaagtctga cgcaggaaat aagaattgtc agagaaagca
    10621 atagtgaaat cgtaggctat gaatagaaac gtgatagcga ggagcatata gtggataagg
    10681 tagcgagaaa ttttaaagta taaaagatag tcttaatcta tatatgtaaa tcacaaaagt
    10741 aattgaattc gggataaggt tggtgtgaaa agacatagta aactgaatct tgaatactag
    10801 aatgatactt ctacaatatt gttataattt aatttgaatt ccaaaatcac attgttccgt
    10861 ccgtatttca ttttactgta tgtcttccta aactccaaag tttctgcgtc aaatttccta
    10921 ttttcactgt agtctttgac acttcgaacg acaatttgaa tcatatattc aaaaaaaatg
    10981 aaaaatttgt gccaacaagc ctaaatattc tgaaaatttg tttgattttt aatggataat
    11041 gtgatataat ggttgtcaat ctataattca cataaacaga ggagtagaaa atgaaaaaaa
    11101 atcgtgtatt tgctacagca ggtcttgttt tattagcagc aggtgtactt gcagcatgca
    11161 gttcttcaaa atcatctgat tcatcagccc ctaaagctta tggctatgtt tatacagcag
    11221 acccagaaac cttggactac ctgatttcaa gtaaaaatag tacaacagta gtgacttcaa
    11281 atgggattga tggtttattc actaacgata attacggtaa tcttgctcct gcagttgcag
    11341 aggattggga agtctctaag gatggtttga cctacactta taagattcgt aaaggggtta
    11401 aatggtttac ctctgatgga gaagaatatg cagaggtgac ggctaaagat ttcgtgaacg
    11461 gtttaaaaca cgcagcagat aaaaaatcag aagctatgta tttagctgaa aattcggtta
    11521 aaggcttggc agattatcta tcaggaactt caacagattt ttcaacagtt ggtgtcaagg
    11581 cggttgatga ttatacgtta caatacactt tgaaccagcc tgaaccgttc tggaactcta
    11641 agttgaccta ttctattttc tggcctctga atgaagaatt cgaaacatca aaaggaagcg
    11701 attttgctaa accaacagat ccgacatcct tgctttataa tggtccattc ttgttgaaag
    11761 ggttgactgc aaaatcttct gtagagtttg taaaaaatga gcaatattgg gataaagaaa
    11821 atgtccacct agatactatc aatctagctt actatgatgg atcagatcag gagtcgctag
    11881 agcgtaactt cactagtgga gcttatagtt atgcccgtct ttaccctacc agctccaact
    11941 attctaaggt tgcagaagaa tacaaggaca atatctatta cacacaatca ggctctggga
    12001 ttgctggtct gggtgtgaat attgatcgcc aaagttacaa ctatacttct aaaactacag
    12061 attcagagaa agtagctact aagaaggcat tgcttaacaa agatttccgt caagccttga
    12121 attttgctct tgatcgctca gcttactcag ctcaaatcaa tggtaaagat ggagcagctt
    12181 tagcagttcg taatttattt gtaaaaccag actttgtttc agctggtgag aagacctttg
    12241 gtgatttagt cgctgctcaa cttcctgctt atggtgatga gtggaaaggt gtgaatttag
    12301 ctgatgggca ggatggttta ttcaatgctg acaaggccaa ggcagagttt gcgaaagcta
    12361 agaaagcttt agaagcagac ggcgttcagt ttcctattca tctggacgtt ccagtagacc
    12421 aagcatcaaa aaactacata tctcgtattc agtcctttaa acaatctgta gaaacagttc
    12481 ttggtgttga aaatgtcgtt gttgatattc aacaaatgac aagtgatgaa ttccttaata
    12541 ttacttacta tgctgccaat gcttcatctg aggattggga tgtatcagga ggagtttcat
    12601 gggggccaga ctatcaagac ccatctactt acctggatat tttaaaaaca actagcagtg
    12661 aaactacaaa aacatattta ggatttgata atccaaatag cccttcagta gttcaagttg
    12721 gtttgaaaga atacgataaa ttagttgatg aagctgccag agagacaagc gacttgaatg
    12781 tccgttatga aaaatatgca gcggctcaag catggttgac agatagttca ctctttattc
    12841 ctgctatggc ttcttctggt gcagcaccag tgctttcacg aattgttcca tttactggag
    12901 cttctgcgca aacaggctct aaggggtcag atgtttactt caaatatttg aaattacaag
    12961 ataaagcggt gactaaggaa gagtatgaaa aagctcgtga aaaatggttg aaagaaaaag
    13021 ctgaatcaaa tgagaaagct caaaaagaat tggcaagtca tgtgaagtaa ataatttcta
    13081 atagaacttt ctctccatga ggagaaggtt cttttgggat ttttaaagga aataatatga
    13141 aaaaatatat ttttatgcgt gttttgcggt cattggtttc gattttctta gtaacgactt
    13201 tgacctacac gattatctat accttggttc ctcgaaaatt gattttcaag caggatccta
    13261 actataataa aattgcgaca acggctgata aacgtgataa ctatgaaaat actgtgtttg
    13321 agcgtatggg ctacattgag tattacgata ctaaagagtt gcaagaaaag gcaagtagca
    13381 tggattcttc tgtaacagta gaagcaaatg cgaccaataa agctatttat gaaaagtaca
    13441 tcaatcaatt aggtcatggt tggactttgg gagaatttac tgaaagtggt caattctatg
    13501 ctactcgtga aattccaatt tttgaacgtg tttttcactt ctatgctaac ttgattgaca
    13561 ttgaccatac aaataaaatc caagaccctg aaaatccaga cttgaaacgc taccttcgtt
    13621 ttgaaaatga tccagctatc ggatggtcat tggtcggttc aggaactaaa cataaatatc
    13681 tcttgtactt taacagtcag ttcccatttg ttcatcaaaa ctttgtgaac ttgaatttag
    13741 gtgactctta cccaacctat gctaatacac cagttcttca ggttattact caaggtcaag
    13801 gacaaaccaa aactgcccaa gttcagttcc caacaggtaa gaaaacgtct tctgtaaata
    13861 tttactcaag aacctacaag tcacctagtc aggctgactc tcgtgaagta gctagctatg
    13921 ggaaagatga tccttataca gcgactgaaa gtaattacca atatccatct atgattgtca
    13981 gctctgctat tactggtttg attggtttgg ttcttgccta tgctcttgcc gtgccacttg
    14041 gttcagccat ggctcgtttc aagaacactt ggattgatag cctctcaaca ggggctttga
    14101 ccttcttgct tgctcttcca acgattgcct tggtttacat cgttcgattg attggatcat
    14161 ctattgccct tccagattca ttccctatct tgggagctgg agattggcgt tcttacgttt
    14221 taccagcagt catccttggt ttgttgggtg ctcctggtac agccatttgg attcgtcgtt
    14281 acatgattga cttgcaatct caagactttg ttcgtttcgc tcgtgcaaaa ggtttgtctg
    14341 aaaaagaaat ttcaaacaaa cacatcttta aaaatgccat ggttccgctg gtttcaggaa
    14401 ttcctgctgc cattattggg gttatcggtg gtgcaaccct tactgaaaca gtcttcgcct
    14461 tcccaggtat gggtaaaatg ttgattgact ctgtaaaagc atctaataac tctatggtcg
    14521 ttggtcttgt cttcatcttt acatgtattt ctatcttctc acgtcttttg ggagatattt
    14581 ggatgactat tattgaccca cgtattaaat tgactgagaa aggaggcaaa taatgtctac
    14641 aatcgataaa gaaaaatttc agtttgtaaa acgtgacgat tttgcctctg aaactattga
    14701 tgcgccagca tattcttact ggaaatcagt gtttaaacaa tttatgaaga aaaaatcaac
    14761 tgtagtcatg ttgggaatct tggtagccat cattttgata agtttcatct acccaatgtt
    14821 ttctaagttt gatttcaatg atgtcagcaa ggtaaacgac tttagtgttc gttatatcaa
    14881 gccaaatgcg gagcattggt tcggtactga cagtaacggt aaatcgctct ttgacggtgt
    14941 ctggttcgga gctcgtaact ccatcctcat ttctgtgatt gcgacagtga ttaacttggt
    15001 tatcggtgtt tttgtcggtg gtatttgggg tatttcaaaa tcagttgacc gtgtcatgat
    15061 ggaagtttac aacgtcatct caaacatccc acctcttttg attgttattg tcttgactta
    15121 ctcaatcgga gctggattct ggaatctgat ttttgccatg agcgtaacaa catggattgg
    15181 tattgccttc atgatccgtg tgcaaatctt gcgctatcgt gacttggaat acaacttggc
    15241 gtcacgtact ttgggaacac caaccttgaa gattgttgcc aaaaatatca tgcctcaatt
    15301 ggtatctgtt attgtgacaa ccatgactca aatgcttcca agctttatct catacgaagc
    15361 cttcttgtct ttcttcggtc ttggattacc gattacagtg ccaagtttgg gtcgtttgat
    15421 ttcggattat tcacaaaacg taacaaccaa tgcttacttg ttctggattc cattgacaac
    15481 ccttgtcttg gtatccttgt cccttttcgt agttggtcaa aacttagcgg atgctagtga
    15541 tccacgtaca catagatagg agtagaaatg acaaaagaaa aaaatgtaat tttgactgct
    15601 cgcgatattg tcgtggaatt tgacgttcgt gacaaagtat tgacagccat tcgcggcgtt
    15661 tcccttgaac tagtcgaagg agaagtatta gccttggtag gtgagtcagg atcaggtaaa
    15721 tctgttttga caaagacctt cacaggtatg ctcgaagaaa atggtcgtat tgcccaaggt
    15781 agtattgact accgtggtca ggacttgaca gctttatctt ctcacaagga ttgggaacaa
    15841 attcgtggtg ctaagattgc gactatcttc caggacccaa tgactagttt ggaccccatt
    15901 aaaacaattg gtagtcagat tacagaagtt attgtaaaac accaaggaaa aacagctaaa
    15961 gaagcgaaag aattggccat tgactacatg aataaggttg gcattccaga cgcagataga
    16021 cgttttaatg aatacccatt ccaatattct ggaggaatgc gtcaacgtat cgttattgcg
    16081 attgcccttg cctgccgacc tgatgtcttg atctgtgatg agccaacaac tgccttggat
    16141 gtaactattc aagctcagat tattgatttg ctaaaatctt tacaaaacga gtatcatttc
    16201 acaacaatct ttattaccca cgaccttggt gtggtggcaa gtattgcgga taaggtagcg
    16261 gttatgtatg caggagaaat cgttgagtat ggaacggttg aggaagtctt ctatgaccct
    16321 cgccatccat atacatggag tctcttgtct agcttgcctc agcttgctga tgataaaggg
    16381 gatctttact caatcccagg aacacctccg tcactttata ctgacctgaa aggggatgct
    16441 tttgctttgc gttctgacta cgcaatgcag attgacttcg aacaaaaagc tcctcaattc
    16501 tcagtatcaa agacacattg ggctaaaact tggcttcttc atgaggatgc tccaaaagta
    16561 gaaaaaccag ctgtgattgc aaatctccat gataagatcc gtgaaaaaat gggatttgcc
    16621 catctggctg actaggagga aggaaatgtc tgaaaaatta gtagaaatca aagatttaga
    16681 aatttccttc ggtgaaggaa gtaagaagtt tgtcgcggtt aaaaatgcta acttctttat
    16741 caacaaggga gaaactttct cgcttgtagg tgagtccggt agtgggaaaa caactattgg
    16801 tcgtgctatc atcggtctaa atgatacaag taatggagat atcatttttg atggtcaaaa
    16861 gattaatggt aagaaatcgc gtgaacaagc tgcggaattg attcgtcgaa tccagatgat
    16921 tttccaagac cctgccgcaa gtttgaatga acgtgcgact gttgattata ttatttctga
    16981 aggtctttac aatcaccgtt tatttaagga tgaagaagaa cgtaaagaga aagttcaaaa
    17041 tattatccgt gaagtaggtc ttcttgctga gcacttgact cgttaccctc atgaattctc
    17101 aggcggtcaa cgtcaacgta tcggtattgc ccgtgccttg gtcatgcaac cagactttgt
    17161 tattgcagat gagccaattt cagccttgga cgtttctgta cgtgcccaag tcttgaactt
    17221 gctcaaaaaa ttccaaaaag agctcggcct gacctatctc ttcatcgccc atgacttgtc
    17281 ggttgttcgc tttatttcag atcgtatcgc agttatttac aagggtgtta ttgtagaggt
    17341 tgcagaaaca gaagaattgt ttaacaatcc aattcatcca tatactcaag ccttgctttc
    17401 agcggtacca atcccagatc caatcttgga acgtaagaag gtcttgaagg tttacgatcc
    17461 aagtcaacac gactatgaga ctgataagcc atctatggta gaaattcgtc caggtcacta
    17521 tgtttgggcg aaccaagccg aattggcacg ttatcaaaaa ggactaaact agtaatggtt
    17581 ttataatttc catgtcaatt tttatggaaa ttaggctctt tgtcaactgt agtgggttga
    17641 agtcagctaa gctcgagaaa ggacaaattt cgtcctttct tttttgatgt tcaaagcgat
    17701 aaaaatccgt tttttgaagt tttcaaagtt tcgaaaacca aaggcattgc gcttgataag
    17761 tttgatgaga ttattggtcg cttccagttt ggcattagaa tagtgtagtt gaagggcgtt
    17821 gataatcttt tctttatctt tgagaaaggt tttaaagaca gtctgaaaaa taggatgaac
    17881 ctgcttcaga ttgtcctcaa tgagtccgaa aaatttctca gggtctttgt tctgaaagtg
    17941 aaaaagtaag agttgataga tctgatagtg gtgtttcaag tcttctgaat agcttaaaat
    18001 cttgtcaaga atttctttat ttgttaagtg catgcgaaaa gtagggcgat aaaaacgttt
    18061 atcgctcaat ttacgactat cctgttggat gagtttccag taacg
//
LOCUS       DBERPV010000036        17627 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.36, whole genome shotgun sequence.
ACCESSION   DBERPV010000036 DBERPV010000000
VERSION     DBERPV010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 17627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17627
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.36"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            66..776
                     /locus_tag="ACL8C7_001663"
     CDS             66..776
                     /locus_tag="ACL8C7_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395818.1"
                     /translation="MKLLKNELIKSKIFLFIIVDICIQILVILAIKTYILDISAPYSE
                     LDYNKYWYVLHTLIYMPMIFPIQILYQNLREALIEDNNNGWNIMVINTNNLVKIIYIK
                     VTINIVRCFICYFVYTIFSLIQLGGMGTDMLLTNIIFPNIMSFLLFLPIAIFMQICCI
                     RFDSILAKALPNILLILIVLITFQSDWNIFIPATYYYTEIQSTTNLGIKLLVCIWIMG
                     FEFSLLPKLIKLKEQNLV"
     gene            1319..1540
                     /locus_tag="ACL8C7_001664"
     CDS             1319..1540
                     /locus_tag="ACL8C7_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS1395819.1"
                     /translation="MYRCLRDLREDHDLTQKQIAKILSFTNSAYAKIERGEHTLTADV
                     LVTLSNFYDVSTDYLLGLTDFPDKIRFRK"
     gene            1986..2288
                     /locus_tag="ACL8C7_001665"
                     /pseudo
     CDS             1986..2288
                     /locus_tag="ACL8C7_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            2444..3673
                     /locus_tag="ACL8C7_001666"
     CDS             2444..3673
                     /locus_tag="ACL8C7_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGS1395820.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNRLLK"
     gene            3693..6389
                     /gene="ppc"
                     /locus_tag="ACL8C7_001667"
     CDS             3693..6389
                     /gene="ppc"
                     /locus_tag="ACL8C7_001667"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008964 - phosphoenolpyruvate carboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA];
                     GO_process: GO:0015977 - carbon fixation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HGS1395821.1"
                     /translation="MSLQKLENSSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    6472..6689
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6802..7806
                     /gene="trpX"
                     /locus_tag="ACL8C7_001668"
     CDS             6802..7806
                     /gene="trpX"
                     /locus_tag="ACL8C7_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS1395822.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSIGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            7875..8741
                     /locus_tag="ACL8C7_001669"
     CDS             7875..8741
                     /locus_tag="ACL8C7_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1395823.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            8738..9496
                     /locus_tag="ACL8C7_001670"
     CDS             8738..9496
                     /locus_tag="ACL8C7_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1395824.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFEQDFITILGGN
                     GAGKSTLFNTIAGTISLTSGTIRILGEDVTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLFPRRLASYKDKFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRVIQDLNQEEKAKMKISDYYQLFE"
     gene            9586..11346
                     /gene="dnaG"
                     /locus_tag="ACL8C7_001671"
     CDS             9586..11346
                     /gene="dnaG"
                     /locus_tag="ACL8C7_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HGS1395825.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKVGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTVIFNKSYELYHMDRAKRSSGKASEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAATLKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENGENLQAQIEFLEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            11349..12458
                     /gene="rpoD"
                     /locus_tag="ACL8C7_001672"
     CDS             11349..12458
                     /gene="rpoD"
                     /locus_tag="ACL8C7_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HGS1395826.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            12472..12801
                     /locus_tag="ACL8C7_001673"
     CDS             12472..12801
                     /locus_tag="ACL8C7_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HGS1395827.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            12835..13959
                     /gene="cpoA"
                     /locus_tag="ACL8C7_001674"
     CDS             12835..13959
                     /gene="cpoA"
                     /locus_tag="ACL8C7_001674"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HGS1395828.1"
                     /translation="MRKFPLFSSSLSFLLLILFKENDIIVVMEKKKLRINMLSSSEKV
                     AGQGVSGAYRELVRLLHRAAKDQLIVTENLPIEADVTHFHTIDFPYYLSTFQKKRSGR
                     KIGYVHFLPATLEGSLKIPFFLKGIVKRYVFSFYNRMEHLVVVNPMFIEDLVAAGIPR
                     EKVTYIPNFVNKEKWHPLPQEEVVRLRTDLGLSDNQFIVVGAGQVQKRKGIDDFIRLA
                     EELPQITFIWAGGFSFGGMTDGYEHYKKIMENPPKNLIFPGIVSPERMRELYALADLF
                     LLPSYNELFPMTILEAASCEAPIMLRDLDLYKVILEGNYRATAGREEMKEAILEYQAN
                     PAVLKDLKEKAKNISREYSEEHLLQIWLDFYEKQAALGRK"
     gene            13975..15300
                     /locus_tag="ACL8C7_001675"
     CDS             13975..15300
                     /locus_tag="ACL8C7_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGS1395829.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLVAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGALYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            15331..15507
                     /locus_tag="ACL8C7_001676"
     CDS             15331..15507
                     /locus_tag="ACL8C7_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HGS1395830.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVRVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            15566..15700
                     /locus_tag="ACL8C7_001677"
     CDS             15566..15700
                     /locus_tag="ACL8C7_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HGS1395831.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            15764..17074
                     /gene="obgE"
                     /locus_tag="ACL8C7_001678"
     CDS             15764..17074
                     /gene="obgE"
                     /locus_tag="ACL8C7_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HGS1395832.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVTNKMDMPESQENLEEFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEVYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            17084..17242
                     /locus_tag="ACL8C7_001679"
     CDS             17084..17242
                     /locus_tag="ACL8C7_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395833.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TTKENPSQ"
     gene            complement(17293..>17627)
                     /locus_tag="ACL8C7_001680"
     CDS             complement(17293..>17627)
                     /locus_tag="ACL8C7_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS1395834.1"
                     /translation="KLLSYSEDLKHHYQLYNKEPEKFFGLIEDNLKQVHPIFQTVFKT
                     FLKNKEKIVNALQLPYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKER
                     TKFVLSQA"
BASE COUNT         5432 a         3002 c         3847 g         5346 t
ORIGIN      
        1 tttatatatt aattcgtaaa ttgaacgaaa gaagttttga gatgaaactt taataggtaa
       61 taaaaatgaa gttacttaaa aatgaattga ttaagagtaa aatattttta tttattattg
      121 ttgacatctg tattcagatt ctagtcattc tagctataaa aacatatatt ttagatattt
      181 cggcaccata ctcagagctt gattataata agtattggta tgttttacac actttaatat
      241 atatgccaat gatttttcct atacaaattt tgtatcaaaa tctaagagag gcattgattg
      301 aagataataa taatggttgg aatatcatgg tgattaacac taataatctc gtgaaaatca
      361 tctatataaa agtaacgata aatatcgtga gatgttttat ttgttatttt gtttatacaa
      421 ttttttcttt aattcaatta ggtggtatgg gaactgatat gttattaacc aatataatat
      481 ttcccaatat aatgtcattt cttttatttt tacctatagc tatctttatg caaatttgct
      541 gtataagatt tgattccatt ttagcaaagg ccttacctaa tattttgctg atacttattg
      601 ttttaatcac gtttcagagt gattggaata tatttatacc tgcaacttat tattatacag
      661 aaattcagtc aactacaaac ttaggtatta aattattagt ttgtatctgg attatgggat
      721 ttgaattttc ccttcttcca aaactaataa aattgaaaga acaaaatcta gtttaaatgt
      781 tgctcgaaaa ttaaataatt gaatacgatt aacaatgaaa caatacaacg tgagtcatga
      841 cttcaaagta attgatttta tgattctggt ttcttacgct taattaagca agttgtattc
      901 actttatcaa attgttatta ctctaaaaag cgtctaacag ctatagagtg tctgtttgct
      961 tctctttact tttattttaa ataattcatt aaccttccgt aagtgcccaa taataaggtg
     1021 tgttgaagaa gtctgagata aaatagttct cagtcacaaa aaaagctata gattcccatt
     1081 ggtgaacagc tccctgtcaa gtagacagta aaataatata aaatcttaag cgacctgatt
     1141 cctgaattcc agtggagtca ggttgttttt taaccgtctt tcttaatatt gtctcaccta
     1201 taatagatat gcttatgaga agtgtttaat aaattaattt tagttcaaaa tgtccaattt
     1261 ggacactttg aatgatttct tagttttata tattatactt ttctcaggag aaagctagat
     1321 gtacagatgt ttgagagatt tgagggaaga tcacgatttg actcaaaaac aaatagctaa
     1381 aatactttcg tttacaaact cagcttatgc taaaattgaa cggggtgagc atacgttaac
     1441 agcagatgta ttggtaactc tctcaaactt ttacgatgtc agtacagact acctattggg
     1501 attgacagat tttcctgata aaattcgctt tagaaaataa tcacctcaat ttcatagagt
     1561 gtgaaaatga ggtgattttt tatttgttct ttgaaaatta aatagtccaa aatggtactt
     1621 tcctcatttg tggagcaaat ttgaatggct cgccatgata agagcgattt taaaaccatc
     1681 aataaaatag agcgatactt tatatgccat gatacaaatg atatacaatg atacttctgg
     1741 ccgttcagcc tgccaacgta aaagagcagc aagtgaaatt cttatgatga cttcatcagt
     1801 catgccacgt tgaatgtgtg agtttgttag ataaacgcaa ttaatcctca aaaggttccc
     1861 cgaacctttt gagttctaca gacgcatcac gtggagtgtg taagcttgtt gctaaaagcg
     1921 taaaaacctt ggaacgaaag gaataataga cttcctgcga aacaaaaata taatacaata
     1981 aaactatgaa tgatgaagca agtaaacaat tgagcgatag ccgtttcaag atccttgtag
     2041 gtgttcagcg cacgactttt gaagagatgt tagctgtgtt aaaaacagct tatcaacgta
     2101 aacgcgcaaa aggtggacga aaaagcaaat taagcctaga cgatctcctt atggtaacta
     2161 ttcaatacat gcgagaatag agcacttatg aacaaattgc ggctgatttt ggcattcacg
     2221 aaagcaactt aatccgtcgg agtcaatggg ttgaagcaac tcttattcaa aatggtttta
     2281 cgatttcaaa ttctgcctta attctgtaaa aacagtaaaa ttcgaaggat tgtaaggtaa
     2341 gagttttttt ctttctgaaa aaatggtata atagcaatca aaactagaaa ataaaacgga
     2401 atttggaaca gatttgtctg tatcctagta gagtggtgat actatgaaga ttagtaagag
     2461 gcacttatta aattattcca tcttgattcc ctacttgctt ttatctattt tgggcttgat
     2521 tgtggtctat tcgaccacca gtgctatttt aattgaagaa ggcaagagcg ccttgcagtt
     2581 ggttcgaaac caaggaatct tttggattgt tagtttgata ctgattgcct taatttataa
     2641 attgagacta gattttttga gaaatgagcg actaatcatt ttagttatat taatagaaat
     2701 gcttttattg ttcttggctc gttttattgg tatttcagta aacggggcat acggttggat
     2761 ttcggttgca ggagtaacta ttcagccagc tgagtactta aaaatcatta ttatttggta
     2821 tttagctcac cgattctcca aacagcaaga agaaatagct acttatgatt ttcaagtttt
     2881 gactcaaaat caatggcttc cccgtgcttt taatgattgg cgattcgttc tcctagttct
     2941 gattggaagt ttgggaattt tccctgattt aggaaatgcg actattttag tcttggtttc
     3001 cttgattatg tatacagtta gtggaatcgc ttatcgctgg ttttcaacca ttctggcgct
     3061 cgtatctgcc gcttctgtct ttgtcttgac cactatcagc ctaatcggtg ttgagacctt
     3121 ttcaaaaatt ccagtatttg gctatgtagc caaacgcttt agtgcctttt ttaatccttt
     3181 tgccgatcgt gctgatgcag gtcaccagtt agctaattct tattttgcca tggtcaatgg
     3241 tggttggttt ggtctaggtc ttggaaactc gattgaaaaa cgaggttatt tgccagaagc
     3301 tcatacagac tttgtctttt ctatcgtgat tgaagaattt ggctttgttg gtgccagtct
     3361 tattttagct ctcttgtttt tcatgatttt gcggattatc ttggtcggta ttcgagcgga
     3421 gaatcctttc aatgccatgg ttgcactcgg tgtcggaggg atgatgttgg ttcaggtatt
     3481 tgtcaatatc ggagggattt cgggcttgat tccatctaca ggagtaacct tccccttctt
     3541 atcccagggt ggaaatagtc ttctagtctt atcagtggca gtagcctttg tcttaaatat
     3601 tgatgccagt gaaaaacgcg ctaagttgta ccgagaattg gaaaatcaac caatgaaccg
     3661 tctgttgaag taggataaag aaaggatagt ttatgtctct tcaaaaatta gaaaattcta
     3721 gtaataaaag tgttgtgcaa gaagaagtct tgattctaac agaattactg gaagatatta
     3781 ctaaaaatat gcttgcccca gagacctttg aaaaaataat acagttgaaa gaattatcaa
     3841 cgcaggaaga ttatcaaggt ctaaaccgtc tagtgactag cttatcaaat gatgaaatgg
     3901 tctatatttc acgctatttc tctatcttgc ctcttttgat taatatttca gaggatgtgg
     3961 atttagctta tgaaatcaat catcaaaata atattgatca ggactattta ggtaaattat
     4021 ctacaacgat taaattggta gcagaaaagg aaaatgccgt tgagatccta gaacacttga
     4081 atgttgttcc ggttttgaca gcccatccaa cacaagtgca acgcaaaagt atgttggatt
     4141 taacaaatca tattcatagt cttttgcgta aataccgtga tgttaagttg gggttgatca
     4201 ataaagataa atggtacaat gatttgcgtc gttacatcga aattatcatg cagacagaca
     4261 tgattcgtga gaaaaaatta aaagtgacta acgaaatcac gaatgctatg gaatattata
     4321 acagctcctt tttgaaagct gtacctcatt tgacgacgga gtataagcgc ttagcgcaag
     4381 cgcatggtct gaatttaaaa caggctaaac caatcaccat gggtatgtgg ataggtggtg
     4441 accgtgatgg aaatccattt gttacagcaa agaccttgaa gcagtctgca ctcactcagt
     4501 gtgaagtcat catgaactac tatgataaaa agatttacca actttatcgt gaattttctc
     4561 tttcaactag cattgtcaac gtcagcaagc aagtcagaga aatggctcgt caatccaagg
     4621 ataactcgat ttaccgcgaa aaagagcttt accgtcgtgc cttgtttgat attcaatcaa
     4681 aaattcaggc aactaaaacc tatctgattg aggatgaaga agttgggact cgttatgaaa
     4741 ccgccaatga tttctacaag gatttgattg ccattcgaga ttctctacta gaaaataagg
     4801 gcgagtcctt gatttcaggt gattttgtgg aattattgca ggcagtagag atatttggtt
     4861 tttacttagc atcaattgat atgcgacaag actctagcgt ctatgaagcc tgtgtggcag
     4921 aactcttgaa atcagcagga attcattctc gttatagcga gttgagcgaa gaagaaaagt
     4981 gtgaccttct cttgaaagaa ttagaagaag atccccgaat tctttctgcg actcacgcag
     5041 aaaaatcaga attattagca aaagaactag ctatttttaa gacggctcgt gttttgaaag
     5101 ataagttggg agatgatgtc atccgtcaga ccatcatttc acatgcaacc agcctttctg
     5161 atatgctaga attagctatt ctgttaaaag aagtaggact ggtggatacg gaaagggcgc
     5221 gtgttcagat tgttcccctt tttgaaacaa ttgaagactt ggatcattca gaggaaacaa
     5281 tgagaaaata tctttctctt agccttgcca aaaaatggat tgactcacga aataactacc
     5341 aagaaatcat gcttggctac tctgacagta ataaagatgg cggttacttg tcatcatgtt
     5401 ggaccctcta caaggctcaa caacaattga ctgctattgg agatgaattt ggcgttaagg
     5461 ttaccttctt ccatggtcgt ggtggtactg tcggtcgtgg tggtgggcca acctatgaag
     5521 ccattacatc tcaaccgctc aagtctatca aggatcgtat ccgcttgacg gagcagggtg
     5581 aagtaattgg gaataaatac ggtaacaaag acgccgctta ctataacctt gaaatgctag
     5641 tatcggcagc tattaaccgt atgattactc agaagaagag cgataccaat accccaaatc
     5701 gttatgaagc cattatggat caagtagtgg accgtagtta cgatatctac cgtgatttgg
     5761 tctttggtaa tgagcatttc tatgattatt tcttcgagtc aagtccaatc aaggctattt
     5821 caagttttaa tattggttct cgtccagccg ctcgtaagac tattactgaa atcggtggat
     5881 tgcgtgctat cccttgggta ttctcatggt cacagagtcg tgttatgttc cctggatggt
     5941 acggggttgg ttcaagcttc aaggaattta tcaataaaaa tccagagaat attgctatct
     6001 tacgagatat gtaccaaaat tggcctttct tccaatcgct tctttcaaat gttgatatgg
     6061 ttttgtcaaa atcaaatatg aatattgctt ttgaatatgc taaactttgt gaagacgagc
     6121 aagttaaggc catctatgag actattttaa atgaatggca agttactaag aacgttatct
     6181 tggctattga aggacatgac gaactcttag ctgacaatcc atatctaaaa gctagtctgg
     6241 attaccgtat gccttacttt aatattctca actatattca gttagagttg attaaacgcc
     6301 aacgtcgtgg agaattgtcc agtgatcaag aacgattgat tcatatcacc atcaacggaa
     6361 ttgcgacagg attgcgtaat tcaggttgat aattttcaag agtgaatgct aaaagtgaat
     6421 atcaaaaaaa ttctaataga ctattgacaa gtagtttaaa aatgatataa tttaaccatt
     6481 cagaaaagta atcatacaaa ctttttagag agtctgtggt agctgaaaac agataagtgg
     6541 caatgatgaa aattgggctg aatgctattt agaatttgaa attataaaaa ttcggtaagc
     6601 acaccttaca gtgcatctcg ttattgcgag actgagcgat agggaaattc cctataattg
     6661 aggtggtacc gcgcatcgac gtcctcacac aagttttttg tgtgaggatt tttttgatgg
     6721 aggttagtat ggaaagaaaa cgatggcgtc gcttgtttag ataagtgaaa tatgttaaag
     6781 gaaataaaaa ggagaaacag aatgaaaaat aaacgtttaa ttggaattat tgctgcatta
     6841 gcagtcttag tagcaggaag cttgatttat tcttcaatga ataaatcaga agctcagaat
     6901 aataaggatg agaagaaaat aaccaagatt ggtgtgcttc aatttgtgag ccatccatcc
     6961 cttgatttga tttataaagg gatccaagat ggacttgcag aagaaggata taaagatgat
     7021 caagttaaaa ttgattttat gaactcagaa ggtgaccaaa gtaaggttgc gacaatgagt
     7081 aaacaattgg ttgcaaatgg aaatgacctt gtggttggta tcgcaacacc agcagcccaa
     7141 gggttggcta gtgcaacaaa agacctaccg gttatcatgg ccgctattac agacccaatt
     7201 ggtgctaact tggttaaaga tttgaaaaaa ccaggtggca acgttacagg ggtatctgac
     7261 cacaatccag ctcaacaaca agttgaactc atcaaggctc tgacaccgaa tgtgaaaaca
     7321 atcggagctc tttactcaag tagcgaagac aattcaaaaa cacaggtcga agaatttaag
     7381 gcttatgctg aaaaagcagg tctgacagtg gaaacatttg cagttccttc aacaaatgaa
     7441 attgcctcaa ctgtcactgt tatgactagc aaggtagatg ctatttgggt tccaattgat
     7501 aacaccattg catcaggatt tccaacggtt gtctctagca atcaaagttc taagaaacca
     7561 atttatccca gtgcgacagc tatggtagaa gtaggtggtt tggcatcagt tgtaattgac
     7621 caacatgacc ttggtgtggc aacaggtaaa atgattgtgc aagtcttgaa aggtgcaaaa
     7681 ccagccgata ccccagtcaa tgtcttttca attggtaagt cagtcatcaa taaaaaaata
     7741 gcacaagaac taggtattac tattcctgag tctgttctca aagaagcagg acaagtcatc
     7801 gaataaataa ggtagggagg aggagactct tcccattttt taaaaagatg aatatagaaa
     7861 ggattaaata aaatatgatt gtttccatta tttctcaagg atttgtctgg gctattctag
     7921 gtctgggaat ctttatgaca tttaggattt taaactttcc agatatgacg acagaaggtt
     7981 ccttccctct tgggggagct gttgctgtca ctttgataac caaaggcgtg aacccatttt
     8041 tagcgacact tgttgctgta ggagcaggtt gtttggctgg aatggcagca ggccttcttt
     8101 atacaaaagg gaagatccca accttgctct cagggatttt ggtgatgact tcttgtcact
     8161 caatcatgct cttgattatg ggacgtgcga atttaggcct gcttggaacc aagcaaattc
     8221 aggatgtttt gccttttgat tcggatttga atcaactctt gacaggtctc atctttgtga
     8281 gtattgttat tgctctcatg ctctttttct tggacactaa actcggacaa gcctatattg
     8341 ctacagggga taatcctgat atggctagaa gtttcgggat tcatactgga cgcatggagc
     8401 tcatgggctt ggtcttatca aatggtgtga ttgcccttgc aggtgccctc attgctcagc
     8461 aagaaggtta tgccgatgtg tctcgaggga tcggggttat cgttgtgggg cttgcaagtt
     8521 tgattattgg agaagttatt ttcaagagtt tgagcttggc agagcgtttg gttactatcg
     8581 ttgtaggttc tatcgcttat caatttttag tgtgggcagt tatcgcactt ggctttaata
     8641 caagttacct tcgtttatac agtgccttga ttttagcagt ctgcctcatg attccaacat
     8701 ttaagcaaac aatcttgaaa ggagccaagt taagcaaatg acagcaattg tagaattaaa
     8761 aaatgcaacc aaaatcgtta aaaatggctt tgatgaagaa aagattattt taaatgatgt
     8821 ttccttagaa atttttgaac aggactttat cacgattttg ggcggaaatg gtgctggtaa
     8881 atcaaccctc tttaacacta ttgcaggaac catatcacta accagtggaa ctatccgtat
     8941 tttaggtgag gatgttacca agttttcacc agagaagcgc gctaagtatc tgtctcgagt
     9001 cttccaagat ccaaagatgg ggacagctcc tcgtatgaca gtggcagaga atctcctgat
     9061 tgccaagttt cgtggtgaaa agcgtggact atttccgaga cgtctggcta gctataagga
     9121 taagtttcag gcgaccattg aaaaagtggg aaacggtctt gagaaacact tgaatacacc
     9181 gattgagttc ttatcaggtg gacaaagaca ggctttgagt ctcttgatgg caaccttgaa
     9241 gcgacctgaa ttactcttgt tagacgagca tactgctgcc ctggatccaa agactagtgt
     9301 tgctttgatg gaattgacag atgaatttgt taagaaagat caattgacag cccttatgat
     9361 tacccatcat atggaagatg ctctcaaata tggcaatcgc ttgattgtca tgaaagaagg
     9421 acgggttatt caagatttaa accaagaaga aaaagcaaaa atgaaaatct ctgattatta
     9481 tcaactcttt gaataaagta gggaaaatga gtgaaatggt ttactttttt tctgaaataa
     9541 agtatactat ataaagtaaa ctatgataac atggaggtat tgtgtatggt tgacaaacaa
     9601 gtcattgaag aaatcaaaaa caatgccaac attgtggaag tcataggaga tgtgatttct
     9661 ttacaaaagg taggacggaa ctatctaggg ctctgtcctt ttcatggtga aaaaacacct
     9721 tctttcaacg ttgtagagga taagcagttt tatcactgtt tcggttgtgg tcgctcaggt
     9781 gatgttttta agttcatcga ggagtaccaa ggggttccct ttatagaggc agtccaaatc
     9841 ttaggtcagc gtgttggaat tgaggttgaa aaaccgcttt atagtgagca gaagccagcc
     9901 tcacctcacc aagctcttta tgatatgcac gaagatgcag ccaaatttta ccatgcgatt
     9961 ctcatgacaa cgactatggg cgaagaggcc agaaattacc tttatcagcg ggggttgaca
    10021 gatgaagtgc ttaaacattt ttggattggt ttagcacctc cagaacgaaa ctatctctat
    10081 caacgtttgt ctgatcagta tcgtgaagag gatttactgg attcaggcct gttttatctc
    10141 tcggatgcca atcaatttgt agacaccttt cacaatcgca ttatgtttcc cctgacaaat
    10201 gaccaaggaa aggtcattgc cttctcaggt cgtatctggc aaaaaacgga ttcacaaact
    10261 tctaagtata aaaacagccg atcgactgta atttttaaca aaagttacga attatatcat
    10321 atggataggg caaaaagatc ttctggaaaa gctagtgaga tttacctgat ggaaggattc
    10381 atggatgtta ttgcagccta tcgggctgga atcgaaaatg ctgtggcgtc gatgggaacg
    10441 gccttgagtc gagagcatgt tgagcatctg aaaaggttaa ccaagaaatt ggttcttgtt
    10501 tacgatggag ataaggctgg gcaagccgcg acattgaaag cattggatga aattggtgat
    10561 atgcctgtgc aaatcgtcag catgcctgat aacttggatc ctgatgaata tctacaaaaa
    10621 aatggtccag aagacttggc ctatctatta acgaaaactc gtattagtcc gattgagttc
    10681 tacattcatc agtacaaacc tgaaaacggt gaaaatctgc aggctcagat tgagtttctt
    10741 gaaaaaatag ctcccttgat tgttcaagaa aagtccatcg ctgctcaaaa cagctatatt
    10801 catattttag ctgacagtct ggcgtccttt gattataccc agattgagca gattgttaat
    10861 gagagtcgtc aggtgcaaag gcagaatcgc atggaaagaa tttccagacc gacgccaatc
    10921 accatgcctg tcaccaagca gttatcggct attatgaggg cagaagccca tctactctat
    10981 cggatgatgg aatcccctct tgttttgaac gattaccgtt tgcgagaaga ctttgcattt
    11041 gctacacctg aatttcaggt cttatatgac ttgcttggcc agtatggaaa tcttcctcca
    11101 gaagttttag cagagcagac agaggaagtt gaaagagctt ggtaccaagt tttagctcag
    11161 gatttgcctg ctgagatatc gccgcaggaa cttagtgaag tagagatgac tcgaaacaag
    11221 gctctcttga atcaggacaa tatgagaatc aaaaagaagg tgcaggaagc tagccatgta
    11281 ggagatacag atacagccct agaagaattg gaacgtttaa tttcccaaaa gagaagaatg
    11341 gagtaataat ggcaacaaaa caaaaagaag taacaacatt tgacgtacag gtagcagaat
    11401 ttatccgtaa tcataagcaa aaagggacag caacagatga tgaaatcaat gcaagtctgg
    11461 ttattccttt taccttggac gctgatggga ttgaagatct cttgcaacgg attcaggatg
    11521 cagggatttc tatcacagat aacgaaggaa atccaagtgc gcgtgttctt agcaatgaag
    11581 aagaaccaga actcagcgat gaggacttga ttgggtcaac ttctgctaag gtcaatgacc
    11641 ctgtccgtat gtacttgaaa gaaatagggg tcgttcctct cttgaccaat gaagaggaga
    11701 aagagttggc actggctgtt gaagctggtg atatcgaagc caaacaacgt cttgcggaag
    11761 ccaatcttcg tttggttgtt tccattgcca aacgctatgt cggtcgtggt atgcagttcc
    11821 ttgacttgat tcaagaagga aatatgggct tgatgaaggc ggttgacaag tttgactatt
    11881 ctaaagggtt caagttttca acttatgcaa cttggtggat tcgtcaggct atcactcgtg
    11941 ctattgcgga ccaagctcgt accatccgta tcccagttca catggttgaa actatcaata
    12001 aattggttcg tgaacagcgg aatctccttc aagaattggg gcaagatccg acaccagaac
    12061 agattgctga acgaatggat atgacacctg ataaggttcg tgaaatcttg aagattgccc
    12121 aagaaccagt atctcttgaa actcctatcg gtgaagagga cgatagccac cttggagact
    12181 ttatcgaaga tgaagtgatt gaaaatccag tggattatac gactcgtatc gtcttgcgtg
    12241 agcaattgga tgaaatctta gatactctta cagaccgtga agaaaatgtt ctgcgtctac
    12301 gttttggact agatgatgga aaaatgcgca cacttgaaga tgtggggaaa gtctttaacg
    12361 taactcgtga gcgtatccgt cagattgaag caaaggcttt gagaaaacta cgccaaccaa
    12421 gtcgtagcaa accgcttcgt gattttattg aagactaaga gtgaggaaaa tatggcttat
    12481 acagaagagc aaattgaaaa catcaaaaca cggattttaa cagccttgga agaagtcatc
    12541 gaccctgagt tgggaatcga tattgtcaat cttggtttga tctatgagat tcgttttgac
    12601 ggtgacacag ggcaaacaga gattgacatg actttgacaa ctatgggttg tcccttagca
    12661 gaccttttga cagaccagat ttatgatgct atgatagagg ttccagaagt aacggatact
    12721 gaggttaaat tagtctggta tccagcctgg acagttgaaa aaatgagtcg ctatgcccgc
    12781 attgccctag gcattaagta aacatataaa agcatgtgag agactgttgg aaaagtgagg
    12841 aaatttcccc tcttttcctc tagtctctcc tttcttttgc tgattttatt caaagaaaat
    12901 gatataatag tagttatgga gaaaaagaaa ttacgcatca atatgttgag ttcaagtgag
    12961 aaagtagcag gacagggagt ttcaggtgct taccgtgaat tagttcgtct tcttcaccgt
    13021 gctgccaagg accaattgat tgttacagaa aatcttccaa tcgaggcaga tgtgactcac
    13081 tttcatacga ttgattttcc ctattattta tcaaccttcc aaaagaaacg ctcagggaga
    13141 aagattggct atgtgcattt cttgccagct acacttgagg gaagtttgaa aattccattt
    13201 ttcttaaagg gaattgtgaa acgctatgta ttttcttttt acaaccggat ggagcacttg
    13261 gttgtggtca atcctatgtt tattgaggat ttggtagcag ctggtattcc acgtgaaaaa
    13321 gtgacctata ttcctaactt tgtcaacaag gaaaaatggc atcctctacc acaagaagag
    13381 gtagttagac tgcgcacaga tcttggtctt agtgacaatc agtttatcgt agtaggtgct
    13441 gggcaagttc agaaacgtaa agggattgat gactttatcc gtctggctga ggaattgcct
    13501 cagattacct ttatctgggc tggtggcttc tcttttggtg gtatgacaga tggttatgaa
    13561 cactataaga aaattatgga aaatccccct aaaaatttga tttttccagg cattgtatcg
    13621 ccagagcgga tgcgcgaatt gtatgctcta gcggatcttt tcttgttgcc tagttacaat
    13681 gagctctttc ctatgactat tttagaagct gcgagttgtg aggctcctat tatgttgcgt
    13741 gatttagatc tctataaggt gattttggag ggaaattatc gggcgacagc gggtagagaa
    13801 gagatgaaag aggctatttt ggaatatcaa gcaaatcctg ctgtcttaaa agatctcaaa
    13861 gaaaaggcta agaatatttc cagagagtat tctgaagagc atctgttaca aatctggttg
    13921 gacttttatg agaaacaagc cgctttaggg agaaagtaaa aagtgaggta atctatgcga
    13981 attggtttat ttacagatac ctattttcct caggtttctg gtgttgcgac cagtattcga
    14041 accttgaaaa cagaacttga aaagcaggga catgctgttt ttatctttac gacgacagat
    14101 aaggatgtca atcgctacga agattggcaa attatccgca ttccaagtgt tcctttcttt
    14161 gcttttaagg atcgtcgctt tgcctaccga ggttttagca aggcacttga aattgctaaa
    14221 cagtatcagc tagatattat ccatactcag acagaatttt ctcttggcct gttggggatt
    14281 tggattgcgc gtgaattgaa aattccagtc atccatacct atcacaccca gtatgaagac
    14341 tatgtccatt atattgctaa ggggatgttg atccggccga gtatggtcaa gtatctggtt
    14401 agaggtttcc tgcatgatgt ggatggggtt atttgcccta gtgagattgt ccgtgacttg
    14461 ctatctgatt ataaggtcaa ggttgaaaaa cgggtcattc ctactgggat tgaattagcc
    14521 aagtttgagc gtccggaaat caagcaggaa aatttgaaag aactgcgtag taaactaggg
    14581 attcaagatg gtgaaaagac gttgcttagt ctttcgagaa tctcctatga aaaaaatatt
    14641 caagcagttt tagtagcctt tgctgatgtt ctgaaagagg aagacaaggt taaactggta
    14701 gtagctgggg atggccctta tctgaatgac ctcaaagagc aagcccagaa cctagagatt
    14761 caagactcag tcatctttac agggatgatt gctcctagtg agacggctct ttactataaa
    14821 gcggcggatt tcttcatttc ggcatcgaca agcgaaacgc aaggtttgac ctacttggaa
    14881 agcttagcca gtggaacacc tgtcattgct cacggaaatc cttatttgaa caacctcatc
    14941 agtgataaaa tgtttggagc cttgtactat ggagaacatg atttggctgg tgctattttg
    15001 gaagccctga ttgcaacacc agacatgaat gagcatacct tatcagagaa attgtatgag
    15061 atttcagctg agaactttgg gaaacgagtg catgagtttt atctggatgc cattatttca
    15121 aataacttcc agaaagattt ggctaaagat gatacggtca gtcagcgtat ctttaagaca
    15181 gttttgtatc ttccgcaaca ggtggttgct gtacctgtaa aaggatctag acgcatgttg
    15241 aaggcttcaa aaacacagtt gatcagtatg agagactatt ggaaagacca tgaagaatag
    15301 aaagaggaac agctatgaaa aaaacaatta atgagaagcg gtcgtgataa aaagattgcg
    15361 ggtgtttgtg ctggggtggc ccattatctg gatatggatc cgactatcgt tcgagtcatt
    15421 tggggtgttc ttacttgctg ttacggagct ggaattgtag cttacattat tttatggatt
    15481 atcgcaccag tagcaactga ctattgaaaa ctagctcaat tcatgctaag ataatagaaa
    15541 atagaatgta acgaaggaga gaaaaatggc atttggagat aatggaaatc gtaaaaaaac
    15601 tatgtttgag aaaataacct tgtttatcgt gattatcatg ctagtagcaa gtttattggg
    15661 aatttttgca actgcaattg gtgccctcag taatctataa aatagattca agaaaattta
    15721 gtgactggga tttcccagcc cttttttaaa gtgagaagaa ataatgagta tgtttttaga
    15781 tacagctaag attaaggtca aggctggtaa tggtggcgat ggtatggttg cctttcgtcg
    15841 tgaaaaatat gtccctaatg gaggcccttg gggtggtgat ggtggtcgtg gaggcaatgt
    15901 ggtcttcgtt gtagacgaag gactacgtac cttgatggat ttccgctaca atcgtcattt
    15961 caaggctgat tctggtgaaa aagggatgac caaagggatg catggtcgtg gtgctgagga
    16021 ccttagagtt cgagtaccac aaggtacgac tgttcgtgat gcggagactg gcaaggtttt
    16081 aacagatttg attgaacatg ggcaagaatt tatcgttgcc cacggtggtc gtggtggacg
    16141 tggaaatatt cgtttcgcga caccaaaaaa tcctgcaccg gaaatctctg aaaatggaga
    16201 accaggtcag gaacgtgagt tacaattgga actaaaaatc ttggcagatg tcggtttagt
    16261 aggattccca tctgtaggga agtcaacact tttaagtgtt attacctcag ctaagcctaa
    16321 aattggtgcc taccacttta ccactattgt accaaattta ggtatggttc gcacccaatc
    16381 aggtgaatcc tttgcagtag ccgacttgcc aggtttgatt gaaggggcta gtcaaggtgt
    16441 tggtttggga actcagttcc tccgtcacat cgagcgtaca cgtgttatcc ttcacatcat
    16501 tgatatgtca gctagcgaag gccgtgatcc atatgaggat tacctagcta tcaataaaga
    16561 gctggagtct tacaatcttc gcctcatgga gcgtccacag attattgtaa ctaataagat
    16621 ggacatgcct gagagtcagg aaaatcttga agaatttaag aaaaaattgg ctgaaaatta
    16681 tgatgaattt gaagagttac cagctatctt cccaatttct ggattgacca agcaaggtct
    16741 ggcaacactt ttagatgcta cagctgaatt gttagacaag acaccagaat ttttgctcta
    16801 cgacgagtcc gatatggaag aagaagttta ctatggattt gacgaagaag aaaaagcctt
    16861 tgaaattagt cgtgatgacg atgcgacatg ggtactttct ggtgaaaaac tcatgaaact
    16921 ctttaatatg accaactttg atcgtgatga atctgtcatg aaatttgccc gtcagcttcg
    16981 tggtatgggg gttgatgaag cccttcgtgc gcgtggagct aaagatgggg atttggtccg
    17041 cattggtaaa tttgagtttg aatttgtaga ctaggagact ggtatgggag ataaaccgat
    17101 atctttccga gatgcggatg gtaattttgt ttccgccgca gacgtttgga atgaaaagaa
    17161 attggaagaa ctatttaatc gtctcaatcc aaatcgtgcc ttgagattgg cacgaactac
    17221 aaaggaaaat ccatctcagt aaagaagcta aaaaatcccg gctctttgtc aactgtagtg
    17281 ggttgaagtc agctaagctt gagaaaggac aaatttcgtc ctttcttttt tgatgttcag
    17341 agcgataaaa atccgttttt tgaagttttc aaagtttcga aaaccaaagg cattgcgttt
    17401 gataagtttg atgagattat tggtcgcttc cagtttggcg ttggaataag gtaattgaag
    17461 ggcgttgacg attttctctt tgttctttag aaaggtttta aagacagtct gaaaaatagg
    17521 atgaacctgc ttaagattgt cctcaataag tccgaaaaat ttctctggtt ccttattata
    17581 gagctgatag tggtgtttca agtcttctga atagctcaaa agcttgt
//
LOCUS       DBERPV010000037        17434 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.37, whole genome shotgun sequence.
ACCESSION   DBERPV010000037 DBERPV010000000
VERSION     DBERPV010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 17434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17434
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.37"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..1149)
                     /locus_tag="ACL8C7_001681"
     CDS             complement(<1..1149)
                     /locus_tag="ACL8C7_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HGS1395835.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYQLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTSANDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRKNLSNLRTYRRQNSDNTPRTNWVPSVSNPGTTNANTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLIFDPAQITSRTARGVAVPHGNHYHF
                     IPYEQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPSPQP"
     gene            complement(1403..3136)
                     /gene="ptsP"
                     /locus_tag="ACL8C7_001682"
     CDS             complement(1403..3136)
                     /gene="ptsP"
                     /locus_tag="ACL8C7_001682"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HGS1395836.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            complement(3142..3405)
                     /locus_tag="ACL8C7_001683"
     CDS             complement(3142..3405)
                     /locus_tag="ACL8C7_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HGS1395837.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            3756..3974
                     /gene="nrdH"
                     /locus_tag="ACL8C7_001684"
     CDS             3756..3974
                     /gene="nrdH"
                     /locus_tag="ACL8C7_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HGS1395838.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSSAPVIQTPTEVFSGFQPGKLKQLA"
     gene            4055..6214
                     /gene="nrdE"
                     /locus_tag="ACL8C7_001685"
     CDS             4055..6214
                     /gene="nrdE"
                     /locus_tag="ACL8C7_001685"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HGS1395839.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            6402..7364
                     /gene="nrdF"
                     /locus_tag="ACL8C7_001686"
     CDS             6402..7364
                     /gene="nrdF"
                     /locus_tag="ACL8C7_001686"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HGS1395840.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            7546..8307
                     /locus_tag="ACL8C7_001687"
     CDS             7546..8307
                     /locus_tag="ACL8C7_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGS1395841.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(8586..8843)
                     /locus_tag="ACL8C7_001688"
     CDS             complement(8586..8843)
                     /locus_tag="ACL8C7_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HGS1395842.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTSEELKSLGKWYVSTGK
                     EWICHSDDDLEEFKNLFLNFINPEEWDTISFDSDFMPFQQS"
     gene            complement(8886..10292)
                     /gene="lacG"
                     /locus_tag="ACL8C7_001689"
     CDS             complement(8886..10292)
                     /gene="lacG"
                     /locus_tag="ACL8C7_001689"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HGS1395843.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHACAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGIGRR
                     VAPDYVSRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVNNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            complement(10507..12198)
                     /locus_tag="ACL8C7_001690"
     CDS             complement(10507..12198)
                     /locus_tag="ACL8C7_001690"
                     /EC_number="2.7.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0019197 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase complex [Evidence IEA];
                     GO_function: GO:0015155 - lactose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactose-specific PTS transporter subunit EIIC"
                     /protein_id="HGS1395844.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIESGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGASVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            complement(12198..12515)
                     /locus_tag="ACL8C7_001691"
     CDS             complement(12198..12515)
                     /locus_tag="ACL8C7_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGS1395845.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            complement(12551..13387)
                     /locus_tag="ACL8C7_001692"
     CDS             complement(12551..13387)
                     /locus_tag="ACL8C7_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HGS1395846.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            complement(13621..14601)
                     /gene="lacD"
                     /locus_tag="ACL8C7_001693"
     CDS             complement(13621..14601)
                     /gene="lacD"
                     /locus_tag="ACL8C7_001693"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HGS1395847.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            complement(14603..15532)
                     /locus_tag="ACL8C7_001694"
     CDS             complement(14603..15532)
                     /locus_tag="ACL8C7_001694"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009024 - tagatose-6-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HGS1395848.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKEFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            complement(15543..16058)
                     /gene="lacB"
                     /locus_tag="ACL8C7_001695"
     CDS             complement(15543..16058)
                     /gene="lacB"
                     /locus_tag="ACL8C7_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HGS1395849.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            complement(16089..16514)
                     /gene="lacA"
                     /locus_tag="ACL8C7_001696"
     CDS             complement(16089..16514)
                     /gene="lacA"
                     /locus_tag="ACL8C7_001696"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HGS1395850.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            complement(16671..17168)
                     /locus_tag="ACL8C7_001697"
                     /pseudo
     CDS             complement(16671..17168)
                     /locus_tag="ACL8C7_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234238.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
     gene            complement(17184..>17434)
                     /locus_tag="ACL8C7_001698"
     CDS             complement(17184..>17434)
                     /locus_tag="ACL8C7_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS1395851.1"
                     /translation="YQGLMKIYPQAQTSRKSSKLKPLTVKDKAYNHALSKERSKVESI
                     LAKVKTFKMFSTTYRNHRKRFGLRMNLIAGIINHELGF"
BASE COUNT         5189 a         3601 c         3191 g         5453 t
ORIGIN      
        1 aggttgcgga cttggactag gttctggagt cggttgtgga cttggttgtt ctggtcttga
       61 atctggtacc caatggtttg aacgataacg aaggggaatt atacgagcaa ttcgttcttc
      121 caattcagac atttgttcat aagggataaa gtggtaatgg ttaccatgag ggacagctac
      181 acctctggcg gttcgacttg tgatttgcgc tgggtcgaaa ataaggccat cagattctac
      241 atggcgttga ctcaaaggca gtttgtagag ctgtttcaag agactatcaa tgtcattact
      301 ttgacttgct tgactgttag tgttgctgtt gttgcttgtg ttagcatttg tagttcctgg
      361 attgcttaca gaaggtaccc agtttgttct tggagtgtta tcgctatttt gtcggcgata
      421 ggttcttaaa tttgacagat ttttccgacc agataggaag gcttctgcag cagccaactc
      481 gctagctgat aactcattct taggaatgta atggtaatga tctccatgag gaacgatata
      541 agcatcacca gtatcctcta tgatatcaga agcattaaag atataaccat catctgtggt
      601 gtagcgtccc tgtgaacgtg caaaggctac cgcaccatcg tttgctgaag tccctccttc
      661 acgatgctga ctatgttctt gtttttgccg attgatttct tcttttgtac ggacattatc
      721 cgcgtgggca gcatccttaa ggtaaacata gtattttcca tctaccttaa tcacataacc
      781 acccttgatt tcactgataa tatcctcgtc ctttagctgg tagtttggat ccttcatcag
      841 caattcttca ctgatgatag cgtcataagg aaccttacca ttgtaataat gatagtggtc
      901 gccatgtgaa gtgacatagc cttggtctgt tatcttgatg acgatttgct cagcattgat
      961 tccttcacgc ttgctaacct catcaggagt caaattctcc gttttttgcg tcgcttgttt
     1021 tccatctata taggaaacac gattattttc cttaaccgtt ctagcttgat acagtcccaa
     1081 ctcgtaagaa caaacactta aaatcaaagc tgccgcagaa ccaacaaggt atttcttatt
     1141 aattttcatc gaaactctct ttctatttga tatttctagt tgcaattcat ttctaaattg
     1201 cagaaactcc cctctattac ttaactggtt aatagtttac tcctaaatct ccaacttgtc
     1261 aagaatttta tgaaccattt aagtattttt tgttctgacc actacttttt caaggttgga
     1321 ctttctataa gaaagatttt cttgaaaatt ctttttaaaa tatcaaaaaa atccctgtaa
     1381 ctgagttgca gggacttttc gattaatcaa aattaacgta ttctttttga agttcaagaa
     1441 cttcttccat tgttgagcat tctgtaaggg cacggtttgc gtactcttcc atcttagctg
     1501 tgtcgagttt cttcatcaag ctgcgtgtac gaagtacaga tgttgctgac atagagaact
     1561 catccaagcc cattccgaca agaagtggaa cagcttgttg gtcaccagcc atctcaccac
     1621 acataccagc ccatttacct tcagcgtgag ctgctttgat cacattgtta atcaagcgta
     1681 ggattgatgg attgtatggt tggtaaaggt atgaaacttg ttcgttcata cggtctgctg
     1741 ccattgtata ttggatcaag tcgtttgtac caattgagaa gaagtcaact tctttagcaa
     1801 attggtctgc aagcatagcc gctgcaggaa tctcgatcat gataccaact tgaatgttat
     1861 ccgcaactgc aacaccttca gcaagaaggt ttgctttttc ttcatcaaag actgctttcg
     1921 ctgcacggaa ttctttcaag agcgcaacca ttgggaacat gatacgcaat tgaccgtgaa
     1981 cagacgcacg aagaagagca cggatttgtg tgcggaacat agcatctcca gtctcagaga
     2041 tagagatacg aagagcacgg aatccaagga atgggttcat ttcgtgaggc atatcgaagt
     2101 aaggaagttc cttatctcca ccgatatcca ttgtacgaac gacaacaggt ttaccgttca
     2161 ttccttcaag aacagccttg tatgcttcat actgctcatc ttcagttggg aagtcttgag
     2221 aatccatgta caagaactct gtacggtaaa gtccaacagc ttctgcaccg ttgttgttaa
     2281 caccttcaac gtcttttgga gtaccaatat tggcagccaa ctcgaagtgt ttaccgtcag
     2341 cagtcactgt ttgagcatct ttcaaaagtg cccattcagc tttttgtttc gcataggctt
     2401 caccagctgc tttaaattct gccgcttgtt catctgttgg gttgataatc acttctccag
     2461 tgatcccgtt aacagcaagg atgtcaccgt ctttaacgat ttcagtgatg ttgtttgtac
     2521 ctaatacagc agcaatttca agtgtacgtg ccatgatagc tgagtggctt gtacgtccac
     2581 caatgttggt tacaaaagct tttacaaagt ttttgtccaa ttgagctgta tctgaaggag
     2641 tcaagtcatg cgcaatcaca atcacttctt cattgataga agctgggttt ggcaattttt
     2701 taccaagaag gtttgccaat acacgttttg tcacgtcgcg gatatccgct gcgcgttctt
     2761 gcatgtatgg gttgtcttcc atgccttcaa agatagtgat aaacatatct gtaacttctt
     2821 tcagacctgc ttctgcattc actttcttcg cacggatagt ttccttgatt tggctgatca
     2881 tttctgggtc agcaagaacc attaagtgag catcaaaaac ttgagctgct tcttcaccga
     2941 gcgtacctac tgctttctcg cgaataacag aaagctcgtc ttgtgatgcc tgtagagcgg
     3001 catcaaggcg agcttcttct gcgtttgtat cttcgactgt aatagtctca aatgacaaat
     3061 ccggctgaac gagtagatat gcttttgcaa ctgcaacacc gtcagatgct gcgattcctt
     3121 taagcatttc tgtcatttcc cttatgccaa tccttctttt tccattgttt ctgagattgc
     3181 agcgatagcg tcatctgcat ctgcaccttc agctgagata gttacgtcag caccttgacc
     3241 aacaccaaga ctcataacac ccataattga tttaaggtta actgatttac ctttgtactc
     3301 aagagtgata tctgaagcaa atttgctagc agtttgtacc aacaatgttg ctggacgtgc
     3361 gtgaatacct gtttctgcca ctacgtggaa atctttagaa gccatagttt gactctcctt
     3421 ttgttctttc tttttttgag ttatatgtga taacccttac aatttagtat tataccatct
     3481 tctaggattt ttttcaagca ttttctggat tttccttcaa tttcctttca gataacttgc
     3541 tgaaaatctt ctatcctaga taacaaaaca caggatatag tttcttcaaa aacaatttat
     3601 aggataatca ttgctatttc acaatacaaa cactatatat tgtgtttata tataaaaaca
     3661 acaaaagaac accactatat ttagtttaaa tcattgacaa aattttattt tctgatatac
     3721 taagatagta ttaaattttg aagaggagtt acacaatggt aaccgtttat tctaaaaaca
     3781 attgtgtcca atgtaaaatg accaagcgtt tcttggacag taataatgtc tcttatcgtg
     3841 aaatcaatct tgatgagcaa cctgagtacg tcgatcaagt taaagagctc ggttttagct
     3901 cagctcctgt tatccaaaca ccaactgaag tcttttcagg tttccaacca ggaaaactga
     3961 aacaattagc ataatcttag tacatcatcc agaagaaact gctttcaggg ctaacttaga
     4021 agcctttctt ttgtaattag ataagggaaa ttttatggga ttaaaacatc ttgaagacgt
     4081 gacttacttc cgtcttaata acgaaattaa ccgtcctgtt aatggacaaa tcatgcttca
     4141 taaagataag gaagccttgg atgctttctt taaagaaaat gtagttccaa acactatggt
     4201 ttttgattca atcaaagaca aaatcaatta cctcattgaa cacaactaca tcgaaacagc
     4261 ctttatcaag aaataccgtc cagagttctt ggaagaattg gctcaattta tcaaagacca
     4321 aaacttccaa ttcaagtcat tcatggcagc ttataaattt tacaatcaat atgccttaaa
     4381 gactaatgac ggtgaatact atcttgaaaa tatggaagac cgtgtcttct tcaacgccct
     4441 ttatttcgct gatgggaatg aagctgttgc aatcgatatt gccaatgaaa tcatccacca
     4501 acgctaccaa cctgctactc cttccttctt gaatgctgga cgtgctcgcc gtggggagtt
     4561 ggtatcttgt ttcctaatcc aagtgacgga tgatatgaac tctatcggac gttctatcaa
     4621 ctcagctctt caactttcac gtattggtgg tggtgtggga attaccctca gcaaccttcg
     4681 tgaagctggt gcacctatca aaggctatga aggagctgct tcaggtgtcg ttcctgttat
     4741 gaagcttttt gaagacagct tctcttactc caaccaattg gggcaacgtc aaggtgccgg
     4801 tgttgtctac ctcaacgtct ttcacccaga tatcatcgct ttcctttcaa ctaagaaaga
     4861 aaacgctgat gaaaaagtac gtgtcaagac tctatcactt ggtgttgtag tacctgataa
     4921 attctacgaa ttggctcgta aaaatgaaga aatgtacctc ttcagccctt actctgtaga
     4981 aaaagaatac ggtgtgccat tcaattacat cgacattact gaaaaatacg atgaattggt
     5041 cgcaaatccc aatattcgca agacaaaaat caaggcgcgg gatttggaaa ctgaaatctc
     5101 taaattgcaa caagagtctg gctatcctta tgtagtcaac atcgatacgg ctaaccgtgc
     5161 aaatcctgtt gatggaaaga ttatcatgag taacttgtgt tctgagattc ttcaagttca
     5221 agaaccaagc ttgatcaacg atgctcaaga attccttcaa atgggaacag atgtttcatg
     5281 taacctgggt tcaaccaacg tggttaacat gatgacttca cctgattttg gtcgttctat
     5341 ccgtgctatg gttcgtgccc ttactttcgt tacagatagt tcacatatcg tagctgtacc
     5401 aacgattgac catggaaata gccaagccca cacttttggt ctcggtgcca tgggactgca
     5461 cagctacctt gcccaacaac tcattgaata tggttcacct gagtctgttg aatttacaag
     5521 catctacttt atgcttatga actactggac cttggtagag tcaaacaata ttgcgcgtga
     5581 acgtggtatt accttccaca actttgaaaa atcagactat gctaacggaa gttactttga
     5641 caagtatgta actggtgaat ttgttccaac atcagaccgt gttaaagaac tcttcaaaaa
     5701 tgtttttatc cctggtgttg ctgattgggc tgaacttcgc gacaaggttc aagaagatgg
     5761 tctttaccac caaaatcgcc ttgctgtagc gccaaatggt tctatcagct atatcaacga
     5821 cgtttctgct tctatccacc cgattacgca acgtatcgaa gaacgccaag agaagaaaat
     5881 tggtaaaatc tactaccctg ctgctggctt gtctacagaa accattcctt actacacttc
     5941 tgcctacgat atggatatgc gtaaagtcat cgatgtttac gctgctgcga ctgaacacgt
     6001 ggatcaagga ctttcactca ccctcttcat gcgcagtgac attccaaaag gcctttacga
     6061 atggaagagg gaaaataaac aaacgacacg tgatttgtcc atccttcgta actatgcctt
     6121 taacaaggga atcaagtcta tctactacgt ccgtaccttt acagatgacg gtggagaagt
     6181 cggcgccaac caatgtgaaa gctgtgtgat ttagtttcta gcatagaaac actatttttc
     6241 cctaagcagc actgataaaa tcaaatctac tatgtcataa cataatttat gtaacatttt
     6301 aaaagtcggg cttccgactt tttgtgcgat actcctatag aattatggta aagtagaaat
     6361 aattgtgagt tcgcaatact aaacacagaa agagatttta aatggaaact tactacaaag
     6421 ccattaactg gaatgccatc gaagatgtca tcgacaaatc aacttgggaa aaactgacgg
     6481 agcaattttg gctcgataca cgtattccct tatcaaacga cttggatgac tggagaaagc
     6541 tatctaacaa agagaaagac ttggtcggaa aagtttttgg tggtttaacc cttcttgaca
     6601 ctatgcaatc tgaaactggg gttcaagccc ttcgcgcaga catccgtaca ccacatgagg
     6661 aagctgtttt caataacatc caatttatgg aatctgtcca cgctaaatct tactcatcaa
     6721 tcttttctac cttgaatact aaggctgaga ttgaagaaat tttcgaatgg accaatacca
     6781 atccttacct acaaaagaag gctgagattg tcaacgaaat ctacctaaac ggcagcccac
     6841 ttgaaaagaa agttgccagc gtcttcctcg aaaccttcct cttctactct ggtttcttca
     6901 ctcccctcta ctatctcggt aacaacaaac ttgccaacgt tgcagaaatc attaaattga
     6961 ttattcgtga cgagtctgtt cacggaacct acattggtta caaattccaa cttggtttca
     7021 atgaattgcc tgaagaagag caagaaaaac tcaaagaatg gatgtacgac ctactctata
     7081 ctctttatga aaatgaagaa ggctacacag agagtcttta tgacggtgtt ggttggactg
     7141 aagaggttaa aaccttcctt cgctacaatg ccaataaagc tctcatgaac atgggacaag
     7201 atccactttt cccagattca gctgaagatg tcaacccaat cgttatgaac ggtatttcaa
     7261 caggaacttc caaccatgac ttcttctctc aagtcggaaa tggttacctt cttggcgaag
     7321 ttgaagccat gcaagacgat gactataact acggtttaga ctaattctcc atcactctca
     7381 atcatcaaaa agtaaactag aaacatcaaa gttataaccc aacaaaaata tcgaaagttt
     7441 tgaaaacaaa cttcgatatt tttgtttttg tttcattttg ttgtttttgt atttgaatga
     7501 tgagtttgtt tatggtaaga tagtagtagg aaacgaggtg ataatatgct caaacaagaa
     7561 aaattaacca aaattttaga gatagtaaat agcaaaggaa ccataacagt taaacagatt
     7621 atggacgaaa tagccgtttc agatatgact gcaaggcgct atttacagga attagctgat
     7681 aaagatttgc tgattcgtgt gcatggtgga gctgaaaaac ttcgaaccaa ctcccttttg
     7741 actaatgagc gatcaaatat tgaaaaacaa gccctccaaa cggcagaaaa acaagaaata
     7801 gcccattttg caggcagtct agtagaagaa agagaaacta ttttcattgg accaggaaca
     7861 acattagagt tttttgcgcg tgagttgcct attgacaata tccgcgtcgt aaccaacagt
     7921 ctacctgttt ttctgatttt aagcgaacga aaattaacag atttgatttt gataggtgga
     7981 aattatcgcg atattacagg tgcttttgtt ggcacattga ccctacaaaa tctctctaat
     8041 ctccaatttt ctaaagcttt cgttagctgt aatggtattc aaaacggagc tctagctact
     8101 tttagcgagg aagagggaga ggctcaacgc atcgctttaa ataattctaa taaaaaatat
     8161 ttactcgcag atcatagtaa gttcaataag tttgattttt atacttttta taatatatca
     8221 aatcttgata ctattgtttc agattctaaa ctaagtgatt caatcctttt taagctatct
     8281 aaacacatta aagtcatcaa gccttaataa actgaaagag cctgggtaac aactcaattt
     8341 cagaagaaaa aaagtaaatc ttcccacaat aaaaagcata gtatcaggtg ttgaaacacc
     8401 tgatactatg cttttttcta tatcaaagac tttttgccca attcctcaaa gctatacatt
     8461 gagaaatctg cgactcgctt cctagtttaa agttgctctt tgattttcat tgagtataag
     8521 caacgtgatt agataagagt tttacagagt actaaatata agatttaact tttttgagaa
     8581 attggttacg attgttgaaa cggcataaaa tctgaatcaa aggagatagt atcccattct
     8641 tcaggattga taaaatttaa aaatagattt ttaaattctt ccagatcatc atctgaatga
     8701 caaatccatt ctttaccagt cgagacatac cattttccaa gacttttcaa ttcttcactc
     8761 gtcaaacacg gtatttgaga gcatttttcg aaatttataa tataaacttt ttcataaata
     8821 gattggataa aatctttgaa catctttttg actcactaaa attctatatc taatgactaa
     8881 ttctactagt ctataatctg agtttccgct actttcttgt accagtgagc tgatttctta
     8941 ggataacgtt cttgagtttc aaaatctaca tagaagagac cataacgttt ctcataaccg
     9001 tttgaccatg agaagacatc cattaatgac caaatgaagt aaccttttac attagctcca
     9061 tctgcaatcg catcagacaa gatctccaag tgttgtttca cgtaatcaat acgaccatca
     9121 tcgtaaacag tgttattaac gaactcatct ttatagccga gaccattttc agtgatataa
     9181 attttcttgt agttaggata atctttcttc acacgcatga tttggtcata caaaccttga
     9241 gggtagataa tccaatccca atccgtgcgt gatacatagt caggagctac acgacgacca
     9301 atacctttga tttgatactt agagcttcct ttttcacctt taccattatg gataatttca
     9361 gtttctccat caaaggcttc catccagtca ctcatatagt agttgattcc taggaaatca
     9421 ttcaagtctt ttgcagcttc taatgctgta aaatcttctt cacgaagatc caaactacca
     9481 ccattgactg ataagatatg gttgacacct tccatggttt cagctgaata gcgacctaga
     9541 taagttgcgt ctaagatgaa tttattgtgg atgatatctt ccaactctgc tgcacgaaca
     9601 tctgctggat tttcaggatc tagaggatat ttagtaggca gggcgtgaac aacaccaatt
     9661 tcccctttat agcctttctc tttgtacaat tttaccgcgc atgcatgaga caccatcata
     9721 ttgtggtgtg attgaaagac tttggcaagg tcgtactgga tacctggagg gaatttccca
     9781 accaaatatt gaccatcacc gattggtcca atttcattaa aggttgtcca atagtttact
     9841 tctggaaatt cttcaaaaca gaaggcagcg tagtctacaa aatgttcgat attttcacgg
     9901 tttaagaagt ctccatttga gtggagagct tctggcgtgt caaagtgatg aagagttaca
     9961 aagggctcaa catgacgttt gtgacactct gcaaataaat tatgataaaa ctcaacacct
    10021 ttagcattta cttgaccata accagtcggg aaaatacgtg accaggcaat agaaattcga
    10081 atgccattga caccatactc ttctgctagc ttgaggtcaa ctggatatcg attgtaaaaa
    10141 tcactggctg gttctgcagt gtaccagtag ttatcttcaa gatatttatc ccacgctact
    10201 ggtcctttac catcagtatg tgtagcacct tctgcttgat aggcagctgt tgcgccacca
    10261 aaaataaagt cttttggaag tgtttttgtc atttttttca cctatttctt gatttaaata
    10321 aagtaaaagt gagaggagag gagtcagtga gccatccttc tccatctcac ttcttgtacc
    10381 aagtcaccga attgtgacat gaggaggtaa aaacgatatc tttttaccga cgaattaata
    10441 aggcgattag gaaattcgcc atagcgattt ccgtaacgat gggagactgt ttcacagttc
    10501 ctagccttaa tcgaattgct cttgtacgaa tgctagggca ccttttccat cacgagttaa
    10561 tttgatgtat tgagcgcctt ctgtcttagc aagtttaata ccgagcttat ctgtttctgc
    10621 cttcatatct tcaaagtttg aagcaacttg aggagcaagg ataaccaaat caaactctgg
    10681 caacatttca cggtgagcac catagccacc tgctgctgct ttcacaggga cattgtattc
    10741 tgctgctgcc ttgtttagag catttgcaag gagaccactt gttcctccac ctgcacagag
    10801 aacgaggaca tttgtttctt cagtgatggt attttgtgct gcatcgacac ccgctttttc
    10861 aagaatagca tccgcttttg cagtgttgaa gtttgcagca actttttctt tcaattcatc
    10921 attagactta cctgaacgtt cttcttcaag aatttgttcg tcataaactt taaggaatgg
    10981 atagtaaatg acaacgtcaa ccacgattag aagagcagca agaatgaatg atagaacttg
    11041 gaagttcgta ccaagaacta gacctagtgg agctggggtt gtccatggta gattagcagt
    11101 aaatgaattc attccaagtg tttcaataaa gaatttgaaa atccatacgt ttgcgatagg
    11161 agcaaaaata aatggaatga agaagattgg atttaataca agtggtgcac caaacaagat
    11221 tggttcattt acaccgaaga aggtaggaac tactgaagca cgtccgattg cacggttacg
    11281 ttttgatttt gttaaccaca taaacatgaa tggaacaacc agtgtcgcac cagtaccacc
    11341 catggtaacg ataaacattt gtgtaccaga agtaagaatc ttgtcagcgt gcataccttg
    11401 ttggagaagg ttcaagttga cttcagcatt tgcataggta atagctgcga tagcaggttc
    11461 aacgatagat ggaccatgaa taccaacaaa ccagaagaag gcaaaggcac caaagataat
    11521 ggtgatacct agataaccat cagcagcaga gaataatggt gcgaagaatt taccgattga
    11581 ttcagctacg cttgcaccga caaaatgacg agctagtaaa tcaagagcat aaagagaaac
    11641 cactgataga gtgaatggaa tcacatcttt aaagacttgt gagatatttg gtggaacttc
    11701 gtcaggcata cgaatagtga cgttgttctt aacacagacc ttatagatgg ctacagtaac
    11761 gaaggcagca aggaaggctg aaagcaaacc ttttgtcccc aagaatccag tagctagacc
    11821 actttcgata ggatcagctg ccaacatcaa caaaccaaca attgctgcca acaatgttga
    11881 catatagttg atttgattgg ttttttccat gctccggttt actgagtcag tcaatgactt
    11941 agctgttgta ccagctacca agagagccag aatacccata gaatagctat aaggtttcat
    12001 cagaaaggct acaacttcat cagaccattt aaagccccat gagtttggta caaaggcaat
    12061 caagataaag atacttgaga agagaataac aggcatacct gcaatgaaac catcacgaat
    12121 agcacgaaga tagatattac gagatagttt ttcaaagaaa ggctttcctt tctcgataaa
    12181 tgcaattagt ttattcatta tttaactcct ctcttgtaga gttcaattaa atggtgcatt
    12241 aggtctttta acaagatagt tgtcatcaag tgatcttgac catgcatcat ggtcacacta
    12301 tacgctaagt cctcaccaga agcttcctta gtcaatagac ttgtttgcgc gtggtgagcc
    12361 tctgcaatac agctaccagc ttcctctacc agagcgtccg ctttttcaaa atcaccagct
    12421 tcagcagcct tcaaggcttc caatagtttt gaacgagcat cgccagcata ggctacgatt
    12481 tcaaaaccta acaatgttac ttcttctcta ttcatgatag aattctcctt atatagtttt
    12541 aaataaattt ttatgacaat aaacgttgga tatgtagaac tagataaact cgttcacttt
    12601 tatacaaatc aagacccgta tgttgcgtaa tcacatcata gatcttggaa ccaatctcga
    12661 aggcttttgg ataggattgt ttaatatgat cttccatatc cagaagtgat tggttatcat
    12721 ctctagatct gtctaaataa tccaagaaat aattcaaatg gatcataaag cgatcataga
    12781 aatggttatt ctttttagtt cgttgaattg catagtccgt taaaacttct tcaacattcc
    12841 tgagaatttc tttcctctta tcaatcgact ccacaagttc cacttcattt tcaccttcag
    12901 cattaatgaa atgataagca atccgaataa tttcgtcctc aggaaaatga tctgctagct
    12961 tctgacggta aatttcaaaa gcttcatttg cgatttgaaa agcgacagga tacttagcgg
    13021 aaatatctgg cagattacta tccttgtacc ttccttgagt tagagcttga taagaacagt
    13081 aaatatgatc tgtcaaggtt acatagagat actcttgaat cggataatga tatttctttg
    13141 atagcttatc aatgatttca taggtcactg tgataaaatc aagcggaaca tctttgagaa
    13201 gagccataaa gttttctctg gactcttcgg tcttcatccg aaagattttc tcaacctgat
    13261 tttcagcaat caaatccccc ttcttctttc cgaatgcaat ccccttacca attacaatca
    13321 cctcttctcc cttatcattt ctgacaagcg agacattgtg attcattgga tttagaattc
    13381 gatacatgtc aacctccttt tatattttaa aggtatatga gtacaaaaaa tgaccacaaa
    13441 tgaactagaa aatcagctga tttctaattc acctgtgatc atgcctaata ttacttagta
    13501 acactcacct tgtattaact tgtgatttaa gtatagcaca agtaagttat tttgtaaacc
    13561 tttacataca acttttttta aattttttta gattcatgtt cctaaactag gaggactttc
    13621 ttacacacgt tctttccatg aagtcgctgt tgtttgaaga actttattga gctcatcaat
    13681 gttttcaaat ccagttgtgc gaagccattc gcgagctgct gcttcaccat ctttgatgta
    13741 agcttcaact gaccctgccc atgtagcacg gccacaaaga actccgttaa agtttgcacc
    13801 tgattcatga gcaaatacaa gagtatcttg gaagagttta gctgatacac cagcactcaa
    13861 gtagatgtat ggcaagttcg ttgcttcatc ttgcgctttg aagaaggctg ctgcttcttc
    13921 acgtgtataa actacttcac cttcagcgaa gccttcaaca tatttaatgt taacaggaac
    13981 ttcaactttc aagacatcaa tgttaaagcg tgggtctgaa aagactttca tagcgccgat
    14041 aactttgtgt ggttttactt tcgcgtattc tacagaacct gcatccgcaa ttttttcatc
    14101 gtaagcaagg atttcaagga agaatgggat atcttcagcc acacactcag aaccgatgcg
    14161 ttcgatgtag gcttgttttt cttgattgag ttcgtctgag ctatctacat catagtaaag
    14221 caagaattta actgcatctg caccttcttc tttaatacgt tttgcagacc aaacatccaa
    14281 gcagtctggc aagcgttttg tgcttgttgt gtcataacct gttttttcat aagcaaggag
    14341 aagaccagct ttttcatcaa gagctttagt tgctggaagt ccatactcag ggtcaagaag
    14401 catagatgaa gcgtatttag tcaattcatc tgctaccaag actttaagtt cttccatttg
    14461 ggccacagtt ggttcttctg tttggtgttg agccatgagg cgtttcaaag caccacgttg
    14521 gtcaaatgca agagctgaga tgataccatt ttcatcagaa agtttttcta agcgtacacg
    14581 tttttgttct gttaaagcca ttttatacct cttttactat taattgatca tatagagctt
    14641 gatagttggc catgttgaca tgaccagtca ttttttcttg agcattgagc ataccaagga
    14701 catttgcctt gatgagtaat tctgcatccg attctttgtg aagaagtcct gaagaaattc
    14761 ctgccacagt agagtctcca gatccaacag gatttaccac ctgaattcta ggaatatcta
    14821 ccttgtagaa agtgtcacca tgtttggcaa aagtaccgtt ggcaccaagt gaaacgataa
    14881 tccattcaat ccctgcaaac aaaggttctt gaagtacttc ttttaattca tccaaatcct
    14941 cagaaacttc tcttccaaga agctgagaca attcttcatt atttggtttg atgactgttg
    15001 gtttatgggg tgattcaaga acagcctgaa gtgctgcacc tgagcagtcc aagactacag
    15061 gcttgccagc ttgattagca agttctacca agctcgcata gtaatcaact ggaaggccag
    15121 ctggcagact acctgagatg gccactactt caactgactc caagagtttt ttgaaatgtt
    15181 ccaaaaagtc ttgaccttcc tgttccaata cttcaggacc tttttcaaga acttctgttt
    15241 ggttgtctcc gtggagaata gcgatacagt tacgagtttc tccctgaatt gagaagaact
    15301 ctttctttac ttgattatcg atatgttcaa ccaaaaactc accaagtttg ccacccacta
    15361 aaccagtagc aagaacagaa tcgccaaatt ctgaaagtac tcgggtaaca ttgagtccct
    15421 taccaccagc cgttttggtt acatccacca cacgattgac agtatcaatc ttcaactcat
    15481 ccaagggata ggaaatatca atggatgggt tcattgtgac tgttaaaatc ataggtcacc
    15541 tcttagtcgt ggtattctcc gcgatcccat ttttcaagga attctgtaaa gaagtttgcg
    15601 tctgtttgtt gagcattgtg actttcaagg tgttcaattt tcgcaatcaa tttcttgttt
    15661 tcttcagatg gtttgtattc agcatgaatg aaagcttcga tgatatcaca cataagcaat
    15721 tcaccagtaa tcttaccacc aaagccgata acgttagcgt tcaattgttc tttagcataa
    15781 agggctgttg tcatatcacg aaccaaggca gaacgaacac ctggaacttt atttacagcg
    15841 ttgttgatac caacaccagt accacagata cataccccaa gatcagcttg accgctagtt
    15901 acagcttccc ctactttttt accaaagatt gggtagtgag tccgtgtatg gtcatatgta
    15961 ccaaagtcaa tgacttcata tccttttgat ttcaaaaatt ctgaaaccgc cattttttca
    16021 tctgttacga tgtggtcgca tccaattgca attctcattt ttaacttacc tttcttactg
    16081 taatctaatt agcccatttt gttcaacatg tcgacccgga tttgatgacg tccaccatcg
    16141 tatttaccgt taacaaatcc tttagcgatg tttttagcca attcatcacc aacaagttgt
    16201 gcacccatag tgatcatacg tgagttgttg tggccacgag tcatataagc tgaacgttcg
    16261 tcagatactt ctgcagcaac cattcctttg atcttagttg caaccataaa tggaccagct
    16321 ccataagcat caatcacgat accaaggttt tgttcttctt tgtttacttc tgcagcaaca
    16381 gcgagagtca catcaacaaa gtcttgacct tcagctgtaa catccacaag gtggaagttt
    16441 tctttttcta agaagtcttt cacaacttct ttcaatctca aacctgcagc atctgcaccg
    16501 ataacaatag acatattgta tactcctttt tattttttct atgctggatt ccagcagtgt
    16561 attggctgtc tttaaaaaac agtcaattag tcctcacaaa cataatatac tactattgtt
    16621 tgaagaagtc aacagtttgt gtttgttttt gttatttatt ttttactttt ttataaaact
    16681 tctatctcaa accctaattc ttcaacctga ttggcttcta agagacaaac attcttctta
    16741 tcttctaaat gatctccttc ttcaaggaat gttgacaagc cagaccatgg ttcaaaggta
    16801 atgaaagatc ccttgttcaa agttgaccag atgatgaggt ttggaaattc tgcaaaatgc
    16861 actttcaatc ccttatcatg tttaagagaa cgaagggcaa ttgttcgaga ttgcaattca
    16921 tccaaagtca ctgcatctgt gctgaaaaga tcataactaa gatctatttc tttttgtccc
    16981 tctagccatg gacttctatc ttggaaatcc aacatacctg tttctgggaa aggacgtgga
    17041 acagagcaaa tctcttcttt ctcaaactct agataataat cttcatagac ttcatcatca
    17101 agtagaagac aattaaatcc tggatgtcca ccaataaagt aaggcctgac cttactagtt
    17161 tctttattag acttcctgca aaactagaat cctagttcat gattgataat gccagcaatc
    17221 aaattcattc gtaatccgaa gcgtttacga tgatttcgat aggttgttga aaacatttta
    17281 aacgttttta ctttggcaag gatgctctca accttgcttc tctccttaga taacgcatgg
    17341 ttataggctt tatctttaac tgttagcggt ttgagtttgc tggatttacg tgaagtttgt
    17401 gcttgaggat atatcttcat gagcccttga taat
//
LOCUS       DBERPV010000038        17046 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.38, whole genome shotgun sequence.
ACCESSION   DBERPV010000038 DBERPV010000000
VERSION     DBERPV010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 17046)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17046)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17046
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.38"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(81..311)
                     /locus_tag="ACL8C7_001699"
     CDS             complement(81..311)
                     /locus_tag="ACL8C7_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395852.1"
                     /translation="MKRVILVAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(329..970)
                     /locus_tag="ACL8C7_001700"
     CDS             complement(329..970)
                     /locus_tag="ACL8C7_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGS1395853.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVALAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPVLVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTFSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(982..1716)
                     /locus_tag="ACL8C7_001701"
     CDS             complement(982..1716)
                     /locus_tag="ACL8C7_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HGS1395854.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMLLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            complement(1767..1916)
                     /locus_tag="ACL8C7_001702"
     CDS             complement(1767..1916)
                     /locus_tag="ACL8C7_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395855.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVI"
     gene            complement(1916..2122)
                     /locus_tag="ACL8C7_001703"
     CDS             complement(1916..2122)
                     /locus_tag="ACL8C7_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS1395856.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(2132..2596)
                     /locus_tag="ACL8C7_001704"
     CDS             complement(2132..2596)
                     /locus_tag="ACL8C7_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395857.1"
                     /translation="MIDKVVRNLLLTFLFCKMTKIINFLTTILVKKKKMCYNVSKLRE
                     KKKGAMMWVLGFILFIIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRLLQEMIGKK
                     PIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFDGE"
     gene            complement(2596..2724)
                     /locus_tag="ACL8C7_001705"
     CDS             complement(2596..2724)
                     /locus_tag="ACL8C7_001705"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395858.1"
                     /translation="MDRTDEVSSKHGFEVVDETDEVSNHTYGKVKLTWFEEIFEEY"
     gene            complement(2784..4073)
                     /gene="hisS"
                     /locus_tag="ACL8C7_001706"
     CDS             complement(2784..4073)
                     /gene="hisS"
                     /locus_tag="ACL8C7_001706"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HGS1395859.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRAYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     RQVTVKNNQTREEVQVLLETISQNFSEIFEKLGFYTQ"
     gene            complement(4150..5397)
                     /locus_tag="ACL8C7_001707"
     CDS             complement(4150..5397)
                     /locus_tag="ACL8C7_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HGS1395860.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMLLPTLFTVFAGIRADYTRAKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLAHTSNFLGLLFTLSIPVGTACFSLVAVWNMQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            complement(5588..6439)
                     /gene="rgg"
                     /locus_tag="ACL8C7_001708"
     CDS             complement(5588..6439)
                     /gene="rgg"
                     /locus_tag="ACL8C7_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HGS1395861.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIMIKSYMKSIDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            6563..6904
                     /locus_tag="ACL8C7_001709"
     CDS             6563..6904
                     /locus_tag="ACL8C7_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HGS1395862.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            complement(7113..8816)
                     /gene="ilvD"
                     /locus_tag="ACL8C7_001710"
     CDS             complement(7113..8816)
                     /gene="ilvD"
                     /locus_tag="ACL8C7_001710"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004160 - dihydroxy-acid dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HGS1395863.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETPIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(9049..9981)
                     /locus_tag="ACL8C7_001711"
     CDS             complement(9049..9981)
                     /locus_tag="ACL8C7_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HGS1395864.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFSSRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEFYNAR"
     gene            complement(9978..10835)
                     /locus_tag="ACL8C7_001712"
     CDS             complement(9978..10835)
                     /locus_tag="ACL8C7_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HGS1395865.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(10839..12185)
                     /locus_tag="ACL8C7_001713"
     CDS             complement(10839..12185)
                     /locus_tag="ACL8C7_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGS1395866.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFIGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(12198..12482)
                     /locus_tag="ACL8C7_001714"
     CDS             complement(12198..12482)
                     /locus_tag="ACL8C7_001714"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS1395867.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(12486..14516)
                     /locus_tag="ACL8C7_001715"
     CDS             complement(12486..14516)
                     /locus_tag="ACL8C7_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGS1395868.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYNDIKMIIKQED"
     gene            14708..15715
                     /locus_tag="ACL8C7_001716"
     CDS             14708..15715
                     /locus_tag="ACL8C7_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGS1395869.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKQISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            15718..15918
                     /locus_tag="ACL8C7_001717"
     CDS             15718..15918
                     /locus_tag="ACL8C7_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGS1395870.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            16070..16252
                     /gene="rpmF"
                     /locus_tag="ACL8C7_001718"
     CDS             16070..16252
                     /gene="rpmF"
                     /locus_tag="ACL8C7_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HGS1395871.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKITKAASAE"
     gene            16268..16417
                     /gene="rpmG"
                     /locus_tag="ACL8C7_001719"
     CDS             16268..16417
                     /gene="rpmG"
                     /locus_tag="ACL8C7_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGS1395872.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(16909..>17046)
                     /locus_tag="ACL8C7_001720"
     CDS             complement(16909..>17046)
                     /locus_tag="ACL8C7_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395873.1"
                     /translation="ESGSMATGWFTVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWV
                     G"
BASE COUNT         5524 a         3598 c         2901 g         5023 t
ORIGIN      
        1 acctgcggct agcttcctag tttactcttt gattttcatt gagtataata caaaaatccg
       61 atgaacttca ccggactctt ttattttgaa tttttgcctg ctttacgctt ttcagcgatt
      121 tcggctgcct ttcgaggcaa gacaatttcc gttatgtaag ccgtcccaaa acgcagtaca
      181 cctgcaatag gagcaaagac aactgctaga tagttataga agaaatcgcc tttgaaggca
      241 taagctagcg ctccaatgat gaaaaataga acgactgcct gaatcactgc tactaaaatt
      301 actcgtttca tgtgacctcc tgactctatt atagcatgag aatcatcaaa aagccgacta
      361 aattattcaa agcgtgaaga gaaatactgt agaccagacc ttttctgcta atgtaagcca
      421 aacccaaact aaaaccaagg ctaaaataga caaaaaattg ttgcacatca cctggaaaat
      481 gaatcaaggc aaatagaaga ctagatacca gaagaaaaat cagggttcgt ttactattgt
      541 cctgcttagg aaagagatag cgtgctaaca tccctctaaa aacaatctct tccgtcaaag
      601 gagcaaaaat aaccacagca aagaatgaga aaagtggttg agaaaaggtc aagtctgtcg
      661 ctatttgttg atttactgaa ggatcatctg gcaagaagaa ttgaacgacc agagataaga
      721 accaaaccaa gacaggaagc caaataaatc gattaaagcc gctcttctca atatgaacag
      781 gagccttctg ataccatttg taaatgccgt acacatatac tccagccaag gccacataga
      841 gtagagtaac agcatagggt gaagcgccta aagcaagcga cgcagtcgcg agcccctgaa
      901 taaagccata gataaataaa aaggatagaa gggctagaag aatccagcca aggtttttaa
      961 gtaatttcat agataactcc tttatttgaa ataacgtttt accataggta actgcatcac
     1021 attgatataa acatggatgg ctcctacaag caagaaagct agtaactgaa tctctcctgt
     1081 caagaaagaa atgataataa gaaaaatata taaggctggt aagacatatt ggtgtaattg
     1141 gaataaaatt cgaaaactct gttccaaatt agcctgacgc tccccttcat cataagaatt
     1201 tatatagttc aagacatcct ttggtgtagc gaaaaattcc aaatcaaact gacgaacaat
     1261 cgcaatggtt ttaaaaagag atttttgagc gactaagaat accacaaaga gtaagaaaga
     1321 aaggaaaaat gtttgagggt ttgtatgcaa tataatcacc tcacttaatg aaataaaaat
     1381 agccaatgga atcgctacac ctgtaatatt aaaagcaatg gttccaaact caagattccg
     1441 atacatttgc acataatagg tttcattcag atcgtcatcc atttcctctt gatacaagga
     1501 atgaaatttt ctgcttttct ttaagaaatt gaaagtcaaa agcatactaa tgaaacctat
     1561 cagtaaacaa atagctgata tccatggcat caaggctttt acatctaaaa taatttcgtg
     1621 ggattcgaca cgtgccttaa acatccctac aaacatgccc aagaaccccc ccaagacaat
     1681 agacatcaaa aataacaatc tacgtttctt tttcatattc attctccttt ttcacttgct
     1741 agatttttgg atttcttttc aatccattaa attactggga tgagagcaaa gtagacccaa
     1801 acaaattggt cgctttgata gggattaaac cagcttaggt ccatcccaat cagtagaaat
     1861 acactgacta ataaagctat gaccactaca taataaatca ctttatactt gttcatcact
     1921 cgtcctcctc caaacgaaat accgattcga ctgtttcgtt gaaaatttga gatattttca
     1981 gggcaatgat aatggatggg gtgtactcat cccgttctag taggctaatg gtctgtctgg
     2041 aaacccctgc cagtttggct aggtcggttt gattgagacc atcgcgagct cgaagctctt
     2101 ttagacgatt ttttagttgc acgttacaca cctactctcc gtcaaattca acggtttgga
     2161 tatcttcaat acgttgcaac ttgaattttt cttttcccgt attatctaca cgtcgtagct
     2221 ttacccattc ctcatcaaca tccacaactt cccagttatc tggcccaata tacactcccg
     2281 ttataattgg tttctttcca atcatttctt gcaataatct cgacatctct gcgtttcctt
     2341 tctcttttcg ctcaagtttt ttgattttat tctctagttt cttgattttt ttagaattat
     2401 tagaataaaa gaaaataata aatagtataa atcctagtac ccacatcata gctcctttct
     2461 tcttttctct taacttgctt acattgtaac acatcttttt ctttttgaca agtatagttg
     2521 tcaaaaagtt tatgattttt gtcattttgc aaaataaaaa ggtcaggagt aagttcctga
     2581 ccactttatc tatcattaat actcttcgaa aatctcttca aaccacgtca gcttcacctt
     2641 gccgtaggta tggttactga cttcgtcagt ttcatctaca acctcaaaac catgttttga
     2701 gctgacttcg tcagttctat ccacaacctc aaaacagtgt tttgagcaac ctgcggctag
     2761 cttcctagtt tgctctttga tttttattga gtataaaatc ctagtttttc aaagatttct
     2821 gagaagtttt ggctgattgt ctcaagtaac acttgcactt cttctcgggt ttggttgttc
     2881 ttgactgtca cttgtctgct ttcgacttcg ctctctccta gggtgatgag ggtcttagcc
     2941 gcaaagacat ctgctgactt gaactgagct ttgagcttac ggttgaggta atcacgctct
     3001 gctttgaaac cttgttggcg aagagcttgg actagttcta gggctttgac atttgctcca
     3061 tcacccaaga ctgcgatata gacatctagg gcattttcga tagggagggc cacgccttgt
     3121 ttttcaagga tgagaagcag gcgctctaca ccaagcccaa aaccaaatcc agcagtttca
     3181 gggcctccaa agtaagcaac caaaccatcg tagcgaccac ccgcacagac tgtcaagtca
     3241 ttgccctcaa tctctgtgat aaactcgaaa atggtgtggt tgtagtagtc cagaccacgc
     3301 accatattgg tatcgatgat gtaatctact ccaagatttt ccaacatctg acgcacagca
     3361 tcaaaatgag cttggctttc ttcatcaaga aagtccaaga tagacggcgc attctctact
     3421 gccaccttgt cttctttttc cttagagtcc aagacacgaa gaggattttc ctccaagcga
     3481 cgttggctat ccttagacaa ggtctccttg agcggtgtca aatagtcaat caaggcttgg
     3541 cggtaggctg cacggctctc aggatttcca agagtgttga ggtgcaattt gacaccttga
     3601 ataccgattt ccttcaaaaa atgggctgcc ataacgattg tttccacatc ggtagctgga
     3661 ttgctagagc caaaacactc aacaccaatc tggtggaatt ggcgcaagcg ccctgcctgt
     3721 ggacgctcat aacggaacat aggtcccata tagtagaact tgcttggctt ttgcacttct
     3781 ggggcgaaga gtttattttc cacataggca cggacaacgg gcgcagttcc ttctggacgg
     3841 agagtaatat ggcggtcacc cttgtcataa aaatcgtaca tttccttggt tacgatatcc
     3901 gttgtatctc cgacagagcg actgataacc tcgtaatgct caaaaatagg cgtgcgcact
     3961 tctgcatagt tatagcgctt gaaaatctca cgggcaaagc cctcaacgta ctgccacttg
     4021 gcagattcag caggtaaaat atcctgcgtt ccttttggtt tttgtaattt catagggaat
     4081 cctctttaaa cttaatagtc ttattttacc ataaatagag ggattaaaac agtaagaaaa
     4141 aattaggatt tagatatcat ttttgagatt aagaattgtc aaaaaaatag ctagcaagga
     4201 aagaccaaca aatagcatcc aagtcaactg catgttccat acggctacta gtgaaaaaca
     4261 agctgttccc acaggtatgg ataaggtaaa caatagacct aaaaaattac tagtatgagc
     4321 tagaacctct ggagctagat ttttcatgag catggcacta atctttggtt gaactttacc
     4381 agacacatac agagtaaaga agagaaatag caaaccaagc acgacttgat tgaataaatt
     4441 agccaaacca actagactaa gtcctacggt cgcccacatc atcaatctag gcaaggactg
     4501 cttcccaaaa taatcattgc ccgtaaggct actgatgatg attgctacta aaacacagaa
     4561 ttgattgata aatagtgcct ctgtataaga aaaattcaag agagaatggc tcaaaaagaa
     4621 gatattataa attccaccca aagcgccacc caaggaatta ataagcaaga cagcaaagag
     4681 cataaaacca aagtttttct gcccactttt aagaaaaacg agacgtaaat ttcggtaaat
     4741 tgttaggaac tggtctttga tagaaagctt ctcatttttt aagttttcac catcagcaga
     4801 tgacattgac aggctcaatt tgctttttcc taaaaagagg atagtggctg atactaggaa
     4861 aaagcaggca ttgattcccg caacgagaga aaaattgttg accgatagag ctaagagcca
     4921 gactccgaaa gcttgaccac caatagctga aatataggtg atgaactgtg aaaaagaata
     4981 agcctccatc aaatcatctt cagctacttt ttccttaata agaggcatac gcaggccacc
     5041 tgcaaaatca ctgatgatat cactaatgac attgatcaaa cacaggctag aaaaggcaaa
     5101 taaactagct tgctgaacaa ctagggctgc cagaaaaaat aaaaccgcct gaaacaaacc
     5161 gctatagacc atccatttga ccttggccct cgtgtaatct gcccgaatcc ctgcaaaaac
     5221 tgtaaagaga gtcggaagaa gcatgacaat attcgccata gcaacagcaa aagatgcttg
     5281 tgacaaggtc gatgcataga cgataaagac cagattgaaa atcgaagcac caaaagcatt
     5341 gaagaagcgt gataaagtca aaattctata agctggattt ctaaacaata gtttcataga
     5401 taatctccct ccttgttcta agttctacat caagaatagc tttagtatag cacttatgaa
     5461 tttgcgaaac gattcttttg aatatatgca acaaataaaa tgagcaaaaa aacgatagaa
     5521 cttttgtaat gacctgagag agggcaatag ttctatcgct tcaaattttt tcttggtttg
     5581 cagatattca acattcggtc gtatttctat agtattcggc agatttatta cagccaagca
     5641 tctcaaaaat acggacagca tcctccatct ttttctggcc ttccttgact ctaccttgct
     5701 tgctatcaag gagaccttct gcccacagat aaacaattcg gaaataggtc tcattttcct
     5761 tgtagaaatg ctcttcgata acacgtttaa aataataggc attggtaaat tcttcacact
     5821 caatactagc taaaaagcca ttcaatagta tagtatgaaa aaggtttcga ttgccagaca
     5881 tttccattag aaaatcagat ttacgtacca tttctcgtac atatctagta aaaagagaaa
     5941 cagataaaaa tggagaactg actgaaaata aattgagttc atagattccc cagatctcgg
     6001 tagaaaacaa ataatcatga aggacttttc cttcctctgc tgttaactct accctttcat
     6061 ctatgctctt catataagac ttgatcataa tggcatttag aatatgtttc tgtttgttgt
     6121 gagaatgggc atgcttttga tactccctgc gatataagtc ctcaagaggt gctatattct
     6181 ttggttccaa gacatctgta atttcttttc tcaactcaga atctgtatca tactggaaac
     6241 ctctcgccag aaagaggatc tcctccacac tggcagatat attttccaga gcaaatagaa
     6301 acttttccac cgaaagctca ctctgacctg tttcaaaacg ggacaacata gacggcgaaa
     6361 attgtcctcc ggttgcttgt ctcagtgaga tatttcttga ttctcgtaat tgtctaaaga
     6421 cttttccaat ctgctccata gacttcccct tgattccgta ttttcttcat tttatcatat
     6481 ttttcagaaa attcatcaaa aacttgccaa attgtcagaa ttatgagaaa atagaggata
     6541 tttatcacgt ggagggactg ctatgagaga cgatatcaaa atcaatgacc gtgctttggc
     6601 cttgcaagac caaattatcg aaaaactaga gaaagttttt gatacagatg tggaattgga
     6661 tgtttacaat ctaggtctga tttatgaaat caatctggat gaaacggggc tctgcaagat
     6721 tgtcatgacc ttcaccgata ctgcctgtga ttgcgccgaa agcctgccta ttgaaatcgt
     6781 ggcaggtctg aaacaaatcg agggtatcaa agatatcaag gttgaagtta cctggtcgcc
     6841 tgcttggaaa atcacacgaa tcagtcgcta tggccgtatt gcccttggac taccacctcg
     6901 ttaagcaggc caatcacttt taaagatgaa aaaagcaagc cgaaaatggc ttgctttttg
     6961 atactcaatg aaaatcaaag ggcaaactag aaaactagcc gcaggttgct caaaacactg
     7021 ttttgaggtt gtggatagaa ctgacgaagt cagtaaccat acctacggca aggcgacgtt
     7081 gacgtgattt gaagagattt tcgagtatga gtttattttt tacctgactt gtccatattc
     7141 cagaagtctg tcacggctcc gcgtgaagca gatgatacga tgtgggcata tttaccgagg
     7201 acaccacggc tgtaaagtgg tggcaaggtt gtttctgcct tgcgtttttc aagttcttct
     7261 tcggatacgg ccatggaaat ttctttggta tcttggtcaa ccgtaacgat atcgccggta
     7321 cggagatagg caattggtcc accatcctga gcttcaggag cgatatgtcc aacaaccaga
     7381 ccataagtac caccagagaa acgtccgtcc gtcaagaggg ccaccttatc tccctgacct
     7441 ttaccaacaa tcattgaaga aagtgacagc atctcaggca taccaggacc acctttaggt
     7501 ccaacaaaac gaacaacgac tacatcgcca tcaacgattt catctgtcag aacggcctga
     7561 atcgcatctt cttctgagtc aaagacctta gctggcccaa cgtgacgacg cactttaaca
     7621 cctgatacct tggcaactgc accgtcagga gcaaggttcc cgttcaagat gataagcgga
     7681 ccatccgcac gttttggatt ttcaagtggc atgataactt tttggcctgg agtcaagtct
     7741 gcaaagtcag ccaagttttc agctacagtc ttaccagtac atgtgatgcg atctccgtga
     7801 aggaaaccat ttgccaacaa gtacttcata accgcaggga caccaccgac ttcgtagagg
     7861 tcttggaaga catactgacc agatggtttc aagtcggcca agtgaggcac acgttcttga
     7921 atcgtattga agtcctcaag tgacaagtca acatttgcgg catgggcaat ggcgagcaag
     7981 tgaagagtgg cgtttgtaga accaccgaga gccatcgtta cagtaatagc atcttcaaag
     8041 gcttcacgag tcaagatatc tgatggtttg agaccaagtt ccaacatctt aacaacagca
     8101 cgtcctgctg cttcgatatc ttctttctta tcagctgatt cagctgggtg agaggatgac
     8161 cctggcaaac tcatccctag aacttcgata gcagttgcca tggtattagc agtatacata
     8221 ccaccacaac caccagggcc agggcaggca ttacattcaa gacgtttcac gtcctcagct
     8281 gtcatgtcac cgtggttcca ttttccgata ccttcaaaga cagaaaccaa gtcgatatct
     8341 ttaccatcaa gatttcccgg tgcaatagtt ccaccatagg cgaaaatagc tgggatatcc
     8401 atattagcaa tagcaatcat agatccaggc atgttcttgt cacagccacc gatagcgacg
     8461 aaggcatcca cgttgtgacc actcatagcc gcctcgatgg agtccgcgat gatgtcacga
     8521 gatgttagag agaaacgcat accaggcgtt cccatagcga tcccgtctgc tacggtaatg
     8581 gttccaaact gtacaggcca agcgcctgca gatttgacac cttctttagc cagtttcccg
     8641 aaatcatgca agtgaatgtt acatggtgta ttttccgccc aagtcgaaat cactcccaca
     8701 atcggtgttt caaagtcctt atctgtcata ccagtcgcac gaagcatagc acggttaggt
     8761 gatttaacca tgctgtcata gatgctactg cggtgacgtt tatctaattc agtcatctta
     8821 tccctcccat ttcaattttt actattatag cacaattttc gcatgaagaa cagaataaaa
     8881 ttcttgaatt ttcagaaaat tctatacaca tgtgaaatat ttaaaattaa aaacaacaaa
     8941 gcggattagt gcactttctg atgaccagaa tatgcttttt aatccgcttt ctttaaataa
     9001 cgtaatgtaa tttttacaga aattctttca gaacagtgta tttaacatct atcttgcatt
     9061 ataaaactct agaaccttct cttttatatt cgattcactc aaaccatact cattaagaag
     9121 ataatccatt ttccctactt gaccgaatct ttcttgaaca cccatccgat gaatttttgt
     9181 tattccatca tcagagaata attcacataa agcactgcca attccaccta tctgattgtg
     9241 gttttctaca gtaaatatag tttttccact taacattgtt tttatctgtt ctggtatcgg
     9301 tttgattcta aataaatcta tcacacctac tgaataacct aatttagaca gttcatctgc
     9361 aactcgaata cttggagcaa ccattatacc agaagcaacg attacaagat cttcaccatg
     9421 tcttaactca atgtagcctt tagaaaaatc ctctccacct tgatacacag gaactggagc
     9481 ttttctaatt gttcgaatat attttagtcc ttttaagtct aatgtctggt tcaatatttc
     9541 acgaaattgg atatcatcag ttgcttcaaa aatgatcgat ttaggaatta aacgtaacaa
     9601 tccaatttct tcaaatggca tatgtgtccc accattcatt tctgcagtta ctcctgcatc
     9661 tgatccaatc acagtggcat ccaattgtgc gtatccaaga gaaataaata attgatcaaa
     9721 tacccttcgt gaagaaaaag gaccaaatgt atgaagataa ggtctaaacc cctgaataga
     9781 caagcctgct gcaaggccga ccatttctgc ttccataatc ccaacattca cataacggtc
     9841 tccaaagtcc ttttcaagat tatgagtagc catcgaactt gacaaatcgg cttctaagac
     9901 tactatatca gaatcacttt gattagcctc taaaaggaag tctctatata catgccgtaa
     9961 ttctttcgta cttctcatca ttctgtttcc tccaattcct gacttaatct ttctacaact
    10021 gaagttaaca tttgtttctc ctctacagta gggcgaagat gatgattgga tttcatttct
    10081 tccagctctt gaaccccttg acctttaata gtatctaata caatgcactt aggtgatgaa
    10141 ttatttgact gttttaattg gacaatccct tcataaattt ctctaatatc tgaacccttg
    10201 accctaatgg attcaaatcc aaatgctgaa aatttttcta cgaaatcacc tggattacaa
    10261 atatcctttg taaaaccatc taattgtttt ttgttatcat caacaaatac aattaagttg
    10321 gataactgtt gatgagaagc aaactgtata gcctcccaac attgtccttc atttaactca
    10381 ccatctccaa caatagcata agtataaaag ggactctttc ttattctctg accatatgca
    10441 agtccagttg caacactaat tccttgtcct aaagagcccg ttgtcatatc tatgcctggc
    10501 gttagatttc tatcaggatg agacggtaat ttggttccat ttgtatttaa agaatataag
    10561 aattctttgt caaagaaacc attcaaatag agtgtactgt atagagctgg tcctccatga
    10621 ccttttgata atatgaaata atctctatct cgtgctgcaa atatttctgg agtcattggc
    10681 attatttcac cataaagcac tgctaaaact tctacgatag acagacttcc tccgtaatgt
    10741 ccgaatccaa gatgattcaa tgttctaaga gtatttaatc ggatgttagt cgcaaatttt
    10801 cttaacccat cttctctatt tttacttaaa atcatccctt attcctcctt tgcagatggc
    10861 tttttaataa aggatactcc aaacataact gctaaaataa gaacaagacc aatcacaatg
    10921 cctgcttgtg agccaaattg atttaacatt cctaaaataa ttcctgatag accaaaatct
    10981 gcatctgaga aagttgatcc ttggaaaccg agtcctccca aaactggcat taaaaagact
    11041 gggagaaaac tgattaaaat accttgtaaa aatgctccaa tagtggctcc acgaacacca
    11101 ccagatgcat tcccaataac acctgcagtc gctccacaga agaaatgagg cacaacgcct
    11161 ggtaagataa caaccgttcc tgaagcaatc ataattgcca tacttactaa accaccaata
    11221 aaactagaga taaatccaat tagaactgca ttaggtgcat aagtataaac aatcggacaa
    11281 tccaaagcag gttttgaatt aggtacaaga cgctctgaaa tacctttaaa ggctggaaca
    11341 atttcgccca aaataaggcg aacacctgct aaaataacaa atacccctgc tgcaaattga
    11401 cctgctaatt gtaaagcata aactagacca cttgtaccac tactgatttc tttttctata
    11461 tattctgacc ctgcaaagat agctacaata atgtaaataa ctgccataga taaagtgata
    11521 ctaacagtac tatcacgtaa aaaagctaaa ctctttggaa atttaatgtc ctctgttgat
    11581 tttgatttgt caccgataag gctaccagta aaaccactca accaatatcc caaagaactg
    11641 aaatgaccta aagccacctt gtcatttcca gttaattgaa ccatatattt ttgcacaaat
    11701 gctggggaaa tactcataat aataccgagt gctaatcctc ctagtaagat gagaggcaag
    11761 ctagtaaagc cagcaactga taaaatgacc gcaatcatac atgccatata tagagtgtgg
    11821 tgccctgtta aaaaaatata tttaaatcga gtaaaacgag cgattaagat attgaacacc
    11881 attcctgcaa acataatcat tgcagtagct gagccatatg ttgttaaagc tacagctaca
    11941 attgcttcat tattcggcac aacgccagat aaatgaaaag catgctcaaa catggtacca
    12001 aatggattta aagaattttg tacaattcct gcaccaccag atacaactaa gaaaccaaca
    12061 aaggtcttaa ttccaccttt aataatatca ggtaatttct tcttctgaag aactaatcct
    12121 aaaattgcaa ttaaagctac taaaatagct ggtgtactaa caatatccaa tatgaacttc
    12181 atcatgacgc tagcctccta tataagtcct ttttcttcac aaagtttagt aattaattct
    12241 cgtagttcat ccatatcaat aatactattt aagatacgaa catctccaag atgactagct
    12301 gaatcagcta gatcacgacc aacaatccaa atatcagctg catttggatc tgctccacct
    12361 aaatcataat gttcaacttc tacatccgaa acattcaaat cactcaatac agattcaata
    12421 ttcatctgta ccataaaact tgaacctaat cctgaaccac aagctgtacc aatttttaac
    12481 attatctaat cctcctgttt aattatcatt ttaatatcat tatagttttt tgatgatatt
    12541 aaagtttgaa catgattttt atctcttaaa attgttgtta aatgtgacaa agcctttaaa
    12601 tgactctcat tatcaatggc tgcaatacaa atcaacaatc ttacctcttg ttctggatta
    12661 tccaataaat aaatcggttc ttccaaaact aacattgaca ttcctatttc attcacacct
    12721 tcatctggcc gagcgtgagg aattgctact cccttcccta aattaataaa aggcccaaac
    12781 tcttctactt tttgaatcat tgcctcaggg tagttctcag ttatcttatc ttgatccaaa
    12841 agcggtttag ctgctaaacg aatcgcctcc ttccatccta atttttgcga actaacctga
    12901 taggtttctt tggtaataag ttgttctagc actggtacaa tttcctttcg atcatttttt
    12961 tgataaagat aattctttaa cgccaatctt aattccaatt cttgtgtaat aattccatat
    13021 cttttgacaa tattcaggat ttgttcaatc tcaaaatctc catactctaa attcggaaaa
    13081 tcttttaaca ctagttctac tagttgtatt gcttgctctt cagtcatcat aaccgaaact
    13141 agataatttg gcttttctgt ctccaccttt atggtagaaa aaaccatatc atagtcacta
    13201 ctagctttca cctgtaaatc atcaatcttt gaggttccta taaactcaat ttgaggaaat
    13261 aatgctaata gattctcttt taacatcaat gaagaactaa caccattagg acaaatgatt
    13321 gctgctttat accatttttg aggcaaagta tctgctttct ttaaataacc tccgaaatgg
    13381 ataacaaaat atgctgtttc actatcaggt atgggattgt caatagcgtc catcaagggc
    13441 atcaaagaat ctttgactaa ttcaaataaa tcaggataat gttctttaac atgcaataca
    13501 tattcatttg aactaggtag gccgaacttt aatctatagt aagccggtat aaggtggcgg
    13561 cgaagatttt ctctcaatcc ttccctttgt ttaaaatgta acaaagaaat atcttccatt
    13621 ctacttataa tagcctctgt taattgatta aagtaaaccg gagcaacatc tacttcacct
    13681 tcaaagcaac ttgataataa aacggtgata tagcgataat catcctcaga aaacaccgta
    13741 tctataattc ccaaatcaac cactgtatcc aataaaatag tggttatatc ttgaataaca
    13801 ggagatacta atgtctctga aagacatact ctttcaacat ccctttgata cctacacaga
    13861 atgaatacta aaccgaaaag gtaaactttt aattgattaa caataggtac tagctgtagc
    13921 ttctcataat aatctttaac tacctgatca atcaaatcat aagttaatga atacccccaa
    13981 ctggataaaa cataatccaa accccaaatc cctatggagg attccagcaa ctcactaacc
    14041 atttgaaaag ctaagcggtg cttattccac tctgaaccgt gtaaagtata accttttgct
    14101 ctactgtacc ctagctccaa atcattatct aacataatct ttcttaatga ttgaatatca
    14161 gataaggttg tattcttact tactttcaaa aagtcttggt aatgattatt cgatataaaa
    14221 tctaatcggc aaaaagtgta aagatagatt aaagctaagc gagtcgactt tggtaaaacc
    14281 aattcatccg acttaataat atctgtcaaa gactgcttcg tacgatttga taaactatag
    14341 cgaccttgct ttttatccag cactatccct ttattagcta gataaggcac taaataatct
    14401 attccttctt tgacttcctt tataggtaag ctcaccttaa cagataattc atataatgat
    14461 agctcacaat gatccatcaa agtcatcaaa ataactagtg ctctataatc aaacatttct
    14521 cttcctttct aactacaatt atagtgtaaa aattataaga ataaaagagt atttgagcac
    14581 aatataatct caccttttaa aagaaattat tgggctgaaa gtttttagtg attatttttc
    14641 aactttctat tgactttata aattaaagtg atatcattta gatatcaaat aacaggaggt
    14701 cattcttatg actgaaaaac taatcaattc aaaaccaaat ggtgtattcg cattgattct
    14761 cattgagttg acaatcgtac ttggtatctt tatatttata atgggggttg gttcggaaaa
    14821 catttttgga attattatcg gacctttact aatcgtaatt gcaggtctag ctcatgctgg
    14881 tttaaaagtt gtcaaacctc aagaagctct ggttctgaca ctctttggta actatacagg
    14941 taccatcaaa gaacctggct tttactttgt caatcccttc agcgtagcag tcaaccctgc
    15001 aaaccacact cgacttggac aaagtggtga tgttagcaca aaatctcctt ttttaggagc
    15061 taaatcatca aatgacaatg atgtaaatct tgaaattggc aagaaacaga tttccctcaa
    15121 agtcatgacc ttgagcaatt ctcgtcaaaa aatcaatgat tgcttaggaa accctgtaga
    15181 aatcggtatc gcggtaactt ggagagttgt cgataccgct aaggcagtct tcaacgttga
    15241 taactacaaa gaatatcttt cattgcaatg tgatagcgcc ctccgtaata ttgtccgcat
    15301 ctatccttac gatgtgtctc ctaatgtgga tactacgggt gatgggcaag cagatgaagg
    15361 tagtctccgt ggctctagcg aaattgttgc taaccgtatt cgtgaagaaa tccaaagtcg
    15421 tgttgaggat gctggcttgg aaatccttga agcacgtatc acttacctag cttatgctcc
    15481 agaaattgct gccgttatgc ttcaacgcca acaagcatct gccattattg atgcacggaa
    15541 gatgattgta gatggtgctg taggaatggt tgaaatggca ctagaacggc tcaatgaagg
    15601 ggaattggta gaacttgacg aagaacgaaa agctgccatg gtttcaaatc tccttgtcgt
    15661 tctttgtggc aatcatgatg cacaaccaat tgtcaacaca ggaagccttt actaaagatg
    15721 gctgaagcta aaaaaaagca gatccccctt cgactctcaa caaagttata cgctgcactc
    15781 gcatcatggg cagaagacga ctttcgttca gtcaatgggc aaatcgaata tctcctcaca
    15841 gagtgtgtca agcaacggaa gaaagacgga aaatacgtat cagaaaccat tgacgaacca
    15901 tttgagattg atatttaaca ccttctcctg tctgccgtgt cggataggag aattttttca
    15961 tctttttttg tcaagtaact ttactttaca aaaaaaatgt gttatcctag tatggttgat
    16021 gaaaatcagt agattgaatc gaatataaat acctaaagga gaaatcaaaa tggcagtacc
    16081 tgcacgtcgc acttcaaaag cgaagaaaaa caaacgtcgt acacactaca aagtaacagc
    16141 tccatctgta aactttgacg aaactactgg agattactca cgttctcacc gtgtatcact
    16201 taaaggatac tacaaaggac gtaaaatcac taaagctgca tcagctgaat aatagaaggg
    16261 agataccatg cgcgtaaata ttacacttga acacaaagaa tctggtgaac gcttgtacct
    16321 tacttctaaa aacaaacgta acactccaga ccgccttcaa ttgaagaaat actcaccaaa
    16381 acttcgcaaa cacgttgtgt ttacagaggt taaataagca ttcaatacga atcaatacag
    16441 aagaaaaacg cttgatcagc gttttttctt tttgttaatt tcactacatt gtaagggaaa
    16501 tcattcgaat gactacattt ttcactacct tttttgaaat aagaatacgg attcggacaa
    16561 ttaaaagcaa gaggaactca aatgtaagtt ggggttcctt ttttgtatat ttttcaaata
    16621 acgcctctac actatttgta gcaaattcac caactacagt tgtatcttag ttaaaataag
    16681 ttagaatatg taagtgagta ccagatatac caagacatcg tcaccatcta aggtatattc
    16741 aaaatacaaa agttgaccaa ctagatttct gaatatcctt atatatccat tcttaaaatt
    16801 ggtttaaata gcgtagtctt ttaaactagt tttgagaatc caaaaaatct tcctacatat
    16861 gtaagaagat tttttagttc agaatgatta gatttagcta atggatacct atcctaccca
    16921 ctcaccgtta gcattgactc gatagccatc gggtgtagtc gtgtttacta ataaatctcc
    16981 tgaattatag gtatagtacc atttaccaga aactgtaaac caaccagtag ccattgaacc
    17041 tgattc
//
LOCUS       DBERPV010000039        14768 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.39, whole genome shotgun sequence.
ACCESSION   DBERPV010000039 DBERPV010000000
VERSION     DBERPV010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14768
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.39"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(205..1827)
                     /gene="groL"
                     /locus_tag="ACL8C7_001721"
     CDS             complement(205..1827)
                     /gene="groL"
                     /locus_tag="ACL8C7_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HGS1395874.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(1843..2127)
                     /gene="groES"
                     /locus_tag="ACL8C7_001722"
     CDS             complement(1843..2127)
                     /gene="groES"
                     /locus_tag="ACL8C7_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HGS1395875.1"
                     /translation="MLKPLGDRVLLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(2283..2678)
                     /locus_tag="ACL8C7_001723"
     CDS             complement(2283..2678)
                     /locus_tag="ACL8C7_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HGS1395876.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(2756..3517)
                     /locus_tag="ACL8C7_001724"
     CDS             complement(2756..3517)
                     /locus_tag="ACL8C7_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGS1395877.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEALKA
                     EFAETFPNQTVWTFLLDVTDMTMVKTVCSDILETIGQIDILVNNAGLALGLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMVKANQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(3550..4176)
                     /gene="ytpR"
                     /locus_tag="ACL8C7_001725"
     CDS             complement(3550..4176)
                     /gene="ytpR"
                     /locus_tag="ACL8C7_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HGS1395878.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(4192..4509)
                     /locus_tag="ACL8C7_001726"
     CDS             complement(4192..4509)
                     /locus_tag="ACL8C7_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HGS1395879.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(4506..4805)
                     /locus_tag="ACL8C7_001727"
     CDS             complement(4506..4805)
                     /locus_tag="ACL8C7_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HGS1395880.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(5055..5135)
                     /locus_tag="ACL8C7_001728"
     CDS             complement(5055..5135)
                     /locus_tag="ACL8C7_001728"
                     /inference="COORDINATES: protein motif:HMM:NF039231.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395881.1"
                     /translation="MASSGKMLRNTYTPDGYYVGNLGAWQ"
     gene            complement(5142..5333)
                     /locus_tag="ACL8C7_001729"
     CDS             complement(5142..5333)
                     /locus_tag="ACL8C7_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HGS1395882.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(5494..6168)
                     /locus_tag="ACL8C7_001730"
     CDS             complement(5494..6168)
                     /locus_tag="ACL8C7_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395883.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLAIIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLTIRGDVAFGKL
                     EIVYVK"
     gene            complement(6174..6620)
                     /locus_tag="ACL8C7_001731"
     CDS             complement(6174..6620)
                     /locus_tag="ACL8C7_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGS1395884.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(6734..7237)
                     /locus_tag="ACL8C7_001732"
     CDS             complement(6734..7237)
                     /locus_tag="ACL8C7_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGS1395885.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVTLSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(7234..7596)
                     /locus_tag="ACL8C7_001733"
     CDS             complement(7234..7596)
                     /locus_tag="ACL8C7_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HGS1395886.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(7662..8693)
                     /locus_tag="ACL8C7_001734"
     CDS             complement(7662..8693)
                     /locus_tag="ACL8C7_001734"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000506433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1395887.1"
                     /translation="MGFLLMGALFIVLPRTMVSAKRINQVLDLHSSIQNPVQVQLTDE
                     NFKGQVEFKDVTFRYAANSEAVIEHVSFKAETGQTVAFIGSTGSGKSTLVNLIPRFYD
                     VSAGEILVDGVNVQDYDFSATAHAGQKVAIVGPTGTGKTTIVNLLMKFYEIDKGSIHI
                     DGVDTKAMTRSEVHDAFSMVLQDTWLFEGTIRDNLIYNQIGISDERMMEASKAVGIHH
                     FIMTLPDGYDTILDDTVTLSVGQKQLLTIARALLKDAPLLILDEATSSVDTRTEELIQ
                     KAMDRLMEGRTSFVIAHRLSTIRNADLILVMKDGNIIEQGNYEELMAQGGFYADLYNS
                     QFTEDEAEE"
     gene            complement(8700..9521)
                     /locus_tag="ACL8C7_001735"
                     /pseudo
     CDS             complement(8700..9521)
                     /locus_tag="ACL8C7_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601671.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(9538..10009)
                     /locus_tag="ACL8C7_001736"
                     /pseudo
     CDS             complement(9538..10009)
                     /locus_tag="ACL8C7_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
     gene            complement(10133..10849)
                     /locus_tag="ACL8C7_001737"
     CDS             complement(10133..10849)
                     /locus_tag="ACL8C7_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS1395888.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(11730..13145)
                     /gene="ply"
                     /locus_tag="ACL8C7_001738"
     CDS             complement(11730..13145)
                     /gene="ply"
                     /locus_tag="ACL8C7_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HGS1395889.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(13156..13566)
                     /locus_tag="ACL8C7_001739"
     CDS             complement(13156..13566)
                     /locus_tag="ACL8C7_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395890.1"
                     /translation="MIKRGDVVALYLPFPTISSDLAVKNHMYICIDNSMTKNKELVKN
                     QTFKPALLTRRLVKNFMIEEPDLARNPFTRPTLIDLDKVFMLDNTVIPTSYLARRRRN
                     VSEELYEEILDYLVQPRLISLNKSEFMQLNPGTY"
     gene            complement(13559..14167)
                     /locus_tag="ACL8C7_001740"
     CDS             complement(13559..14167)
                     /locus_tag="ACL8C7_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395891.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(14180..14638)
                     /locus_tag="ACL8C7_001741"
     CDS             complement(14180..14638)
                     /locus_tag="ACL8C7_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HGS1395892.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
BASE COUNT         4279 a         3422 c         2686 g         4381 t
ORIGIN      
        1 acgcaatgcc tttggttttc gaaactttga aaacttcaaa aaacggattt ttatcgctct
       61 gaacatcaaa aaagaaagga cgaaatttgt cctttctcga gcttagctga cttcaaccca
      121 ctacagttga caaagagcct ataaaaagaa gggttagtca ttccctcctt ttgtgttttt
      181 tataagttgt tttctataga aagcttacat catcccgccc atcatgcttg gatccattgc
      241 tggagctggg gctactggtt ctggtttatt ggctacgact gcttctgttg tcaaaatcaa
      301 gctggctaca gatgctgcat tttgtagggc tgaacgactc actttaactg gatcaatgat
      361 accttgatca atcatgttaa cccactcgcc agttgctgcg ttaaatccta taccaagctc
      421 agcatttttc aaacgatcga taacgataga tccttcaaat cctgcattgt gagcaatttg
      481 acgaacgggt tcttccaaag cacggagaac aatattacgt cctgttgctt catctcctgt
      541 caattccaag gtagcaacag ctggaatcac attggcaaga gctgttccac cacctgcaac
      601 aataccttct tcaacagctg cacgagtagc gttgagggca tcttcaatgc ggagtttcat
      661 ttctttcaac tcagtttcag ttgcggctcc aaccttaata accgctacac cacctgacaa
      721 tttggccaag cgttcttgca atttttcacg gtcaaattca gaagttgtag tttcgatttg
      781 agacttgata accgcaacac ggtgagaaat cgcttcagga tttcctgcac cttctacaat
      841 aaccgtgcta tctttgtcca cggtcactct cgctgcttga ccaagagctt caattgtcgc
      901 atctttcaac tcaagaccaa ggtcttctgt gataactgtt ccgcctgtta agatggcgat
      961 atcttcaagc atggctttgc gacggtcacc aaaaccaggt gccttgactg ctactacgtt
     1021 gaaggttcca cgaatcttgt tcaaaacaag agttggaaga gcctcgccat ccacatcatc
     1081 cgcaataatc aagagtggac gattgctttg gagaatgctt tccaaaagtg gcaagatttc
     1141 ttggatattg gaaattttct tgtctgtaat caaaatgtac ggattttcaa ggtcagccac
     1201 cattttttcg ctatcagtca ccatgtactg tgaaaggtaa ccacggtcaa actgcattcc
     1261 ttctacgact tcaagctctg tttccatacc acgtgactct tcgatggtga tgacaccgtc
     1321 tttgccaact ttttccattg cttcagagat gtactcacca actttttcag aacgagaaga
     1381 tacggctgca acttgagcga tagcttcttt attggcaaca gggatggcgt tgtttttcaa
     1441 agcttcaact gctgcggcaa ctgctgtttc aatcccacga cgaataccga ttggatttgc
     1501 acctgctgtg acgtttttga ttccttcacg gacgatagct tgggtcaaga ctgttgcagt
     1561 cgtagtcccg tcacctgcga tatcattggt tttagaagct acttctgata ctaacttggc
     1621 acccatattt tcaaaatggt cttccaattc gatttctttg gcaatggtca caccgtcatt
     1681 ggtaatcaag ggtgaaccga atgacttttc aagaacgaca ttgcgacctt ttggtcccaa
     1741 ggttacttta acagtgtctg caaggatatc gacaccacga accatggctg aacgggcatc
     1801 tgatgaaaat ttaatttctt ttgacatact tactttctcc ttctattcct caatgattgc
     1861 caaaatgtta gcttcgccta cgatgatgta cttttcatcg ccatctttga catcaagacc
     1921 tgcgtgggct tcaactaaga cacgatctcc agttttaaca cttggagcaa ccaagtcacc
     1981 gttcaaggta cgaacacctt gtccagtagc cacaacttga gctgttttgg ttttttcttg
     2041 ggctgagcct gcaaggacaa agcccccaac ggtttgttct ttttcttcta tttttaagag
     2101 cacacggtcc cctaatggtt tcaacatctg atttcctcca taatgagata gatattatta
     2161 gcactctttg aactggagtg ctaattcata attctattgt atcacttggt cagaaatagt
     2221 caagaaaaaa gtctgacttt ctcaagataa aaagcctgag accaactcag actttttaat
     2281 tcttaaaatg gcaattcttc ctcttccaag accaaatctg ccaaatcttg gcctgcatta
     2341 ttttcacgca tagcacgttg ggcacgactt tccaagagtt ggaatcctgt cacaaggact
     2401 tcggttacat aattcatctg accatttttc tcaaagcgac gggtacgcaa ttctccatca
     2461 acggaaatga gactaccttt ggttgcgtag cttgccaaag tttctgctag tctgccccat
     2521 agaaccatat taacaaaatc agcttcacgt tcaccgtttt ggtctttgta acgacggttg
     2581 acagcgatag ttgctcgcgc taccgacttg tcattgttgg ttttgtgcaa ttctggtgta
     2641 gacgttaaac gcccaatcat gataacttta ttatacatat tttcttcctc ctacttatct
     2701 attcgtagga aatcaaaaaa agttacagaa atttgtaact tttcgaggaa atttcttatt
     2761 ttttatgaat catgaaacct gtcgcctgtt gattggccat aatggtcata tctgtaatct
     2821 gaacacggcg aggctgactg gtcacataga ctactgtgtc tgcaatatcc tgagcttgca
     2881 aggcttctat tccttggtaa acggacgcag ctcgttcttt atcaccatga aaacgcactg
     2941 tagaaaaatc tgtttcgaca attccaggct gaatggtcgt caccttgata tccgttgcga
     3001 tggtatcaat tcgcagtcca tctgaaaagg tcttaactgc cgccttggtg gctgagtaaa
     3061 cagctgcacc agcataggca taaattcctg cggttgaccc catattgata atatgacctt
     3121 gattggcttt taccattgct ggcaagaaac agcgagtgac tgccatcaaa cctttgacat
     3181 tggtatccaa catggtcagc atatccaact cttcatagtc ttgataggga gctaagccaa
     3241 gagccagtcc tgcgttattg accaggatgt caatctgacc tatcgtttct aaaatatcag
     3301 agcagacagt ctttaccatt gtcatatccg tgacatctag gagaaaagtc caaactgttt
     3361 gatttggaaa agtttctgca aactccgcct taagagcttc tagtctgtct atccgtcgtc
     3421 ctgttagaac gacatcctca ccctgctcca gataagcacg cgcaatcgct tcaccgattc
     3481 ctgaggttgc tcccgtaatc actacatttt ttgccatctt atttccttct atcagatgct
     3541 gacaagttcc taggcagtcc agtgtttcgc tgggtcgaac ggtgttccga caacttggtc
     3601 ttctgataat tcaagcaccc cacgtttttg cggagcattt ggcaaatgca attcacgagg
     3661 actacacatc atcccaaaac tcttttcacc acgaagttcg cctgggaaaa tgaaattccc
     3721 ttttggcatc atggcaccag gaagagccac aatggttttc aacccaacac gcgcattagg
     3781 tgctcctgca acgatttgca ctatcttgtc acttgcgact gcaacttggc agatgttgag
     3841 gtggtcactg tctggatgag ctaccatctc gacaatttca ccaacaacaa acttaggttc
     3901 cttatcatta acaatttctt ctgtaaaacc ttccgcctgt aattcttggt tcaaacgagc
     3961 gacttgctca tctgataaaa agacttgacc gcgctctgca atttcaaaca agctcgaaac
     4021 ctcaaaaatg ttccaagcta ctgtttcccc attttctttg aggaaaacac gggctacctt
     4081 gcctttgcgt tccacattca gtttggcatc tccgctattt ttcacgatga ccataaggac
     4141 atcaccgaca tgttctttgt tatacgtaaa aatcattgtt tccttttttt cctatttcaa
     4201 tcctgctaaa aaatcgttaa tttgctcctt acttttacgg tcgcgattga caaaacgacc
     4261 gatttccttg tccttttcta gaacaacaag gctaggaatt ccgtaaacat cccagagttt
     4321 ggccaaatcc atatactgat ctcggtccat tcgaataaag gtgaactctg gattggtctc
     4381 ctcaatctct ggtaaggcag gataaatata acgacaatcg ccacaccagt ctgccacaaa
     4441 aaggaagacc ttcttgcccg ctttttccac taaagatgct aattcttcta aacttgctgg
     4501 ctgtatcata agacttcctc ctcatagact aggtcttcat tttcatagac aaaggtataa
     4561 tgacgaccat cctcaaaaat gacgccacca accaagctct ccagactgct ttcgtaaact
     4621 tgaacataga gggtcgcaat ttcccccatg tcggaaaaat ggtctcgcac aatctctgtc
     4681 aactcttcct gagtcttcat gagcttacgg tcatctgcaa cttttttcgt ggcaagagca
     4741 aggcttccga tacctagcag agccaagcct gccatccaca tttttttagc tttcatacca
     4801 ttcattttaa cacaaaaaag gcttcaggac aaatgaggaa gcagcagaaa agcaagtaaa
     4861 aagcctcttc ctttaaggaa aaggacttct tatactcaat gaaaatcaaa gaccaaacta
     4921 ggaagctagc cgcaggctgc tcaaagcact gctttgaggt tgtagataga actgacgaag
     4981 tcagctcaaa acactgtttt gaggttgtgg atgaagctga cgtggtttga agagattttc
     5041 aaagagtatt attcttattg ccaggcacct aagttgccaa cgtagtaacc atcaggtgtg
     5101 taggtattgc gaagcatctt acctgatgaa gccagataat actacttgcc attgtctttg
     5161 acccaatcat tcgcaatcat ggaaccagaa gaacttacat aataccattc tcccttgtca
     5221 taaacccaag tactgacttt catggttcct gagcaattaa aggcaaaaaa actgtccaat
     5281 atcattcgtt ttttaaaagc atttgacact acatcatcta cgctgtagta catagataca
     5341 tcaaacgtaa aagccaaaat atcgaaaaat atacaacttt taaaggcagc atttcatttt
     5401 ttaaagtcta acaaccatag aactgaaatc agagcaaggc atcaatttcc tactcttagt
     5461 acgtctattt tgatggttga agtgaagatt tttttattta acgtagacaa tttccaactt
     5521 cccaaaagcc acatctccac ggatagtcaa ggttttgctg gttggggcta caggagcgtc
     5581 agccttagct gcaccaaagg aggtttctac tttcaaatct acacgccagt gttgtggaac
     5641 atagacggtt gcatttccga aggccacttc aatatttaaa gttgcaaaat cacctagcat
     5701 ctctgcatta tcatagtaga ttttagcatc cccaaaagcg acttccactt ggtcatctac
     5761 gagatcttga tcttgcttat agaaggtccc gctaccaaaa gcgacttcct tatccgtgac
     5821 gactgttttt ttcccattgt accaccattt tttttcattc cagaacttac ttgaatgcgt
     5881 cagataacca acaccaagta ccaccaagat gctagcccaa ataagagaat gattggtaac
     5941 tggtaacaag tcataagcgt aatttgcaat gatgatcgcc agtaaacctg taaaaactgc
     6001 cgaagtgaga tgacgtctaa ggatggactc aatggactta taagcaaaaa aaacaatacc
     6061 tagtaaaggc catattttac catccaaaga aggaattcca aaattccctt gcagcaagat
     6121 ccaagctgct aaaaccaata aaacaatacc aaatgctttc tttttcatgt tttttacctc
     6181 atgtttctta gattttcttt taggagggat tggtaatgcc gtgagacatg aacctccttg
     6241 tgcgtctgat aaaaggaaat ggtgcccgtt cctgaaaagg acttgtccac tgagtaaatc
     6301 tgacggatgt ttgcgatcgt tgacttggaa actcgattaa aatagcgagg caagatagac
     6361 tccaactcat agagcttgag gcgaacctca taagcttcct tctggttatg agcgtagatc
     6421 ttgctccctt ctgtttcaaa gaagagaatt tctgacaggt ctagataata ttcacctgtc
     6481 cccttgtaaa aagtcaacct cggagccttt gactcttgca agagccgttg caagtctgca
     6541 atttcatctg tcaaagtggg ggtcttgatg acaatttcag tctcctctaa attgccgtca
     6601 atctcaattc gtaacttcat cacatctcct ttctgactct actatatcaa agctaagtta
     6661 ggaatacaag ggcaaaaaag caagtggtca atttgaagca gtaagtggtt gtaggactag
     6721 cttaacttac atgtcagaat aggaagaaaa ggaatcccca caccaaacca caagcatagc
     6781 caaccaagac atccttggga taatgaacac cccctaaaac cctcaccaac cccagcaaag
     6841 ctgaaaagat caagcatact aagccaatag gtagactagc atgcagacag gccatggaga
     6901 tgatagttgc cgaaaagaca tggcgactgg gcatcgaccg tcccgaacta tccttatcaa
     6961 gaaggggaca gatatcccaa gtttcataag gtctcgggtg attgattttc ttacgaaaca
     7021 gggacaaggt cacaaaacct gatgcaggaa taagcacata aaccccaact tgctgaccaa
     7081 gtcctagttg caggtaagtg gtgactagca agatcagata gaccaggggc atggcgactg
     7141 tcatcaaacg attgaaactg cgtaatagga ataaaagaat tggacgacta gttagtctgg
     7201 agctgatatt tcgataccat tcttgataat ttttcattta tgcttctcat acttttctag
     7261 aacttgttga gatgttttcc ccttggcaag ccaatccact agcttgtcca agcgacgtat
     7321 ttcctgcatc agaggatcat caatttcctc aatacggaca ccgcaaatct tccctgtaat
     7381 tgcaattcgt tcagggacat aatatggtgc ttgtcgaaaa aaatctccgt aagtaacatc
     7441 cctatccaga caagcaagaa cgtcactcac ttcataccct gtcaaccaac tggtcacttg
     7501 gtgaactgac tctgcctttc caccctttcg ctcaactttt gcaatcaagg ctaagtagac
     7561 agcagcaaat ttcatattgt ataatttctg actcatactt ctctctttct atgtgtacta
     7621 gtataaataa gaaaaagaag gccgtcaagc cttcttttga tttattcttc tgcttcatct
     7681 tctgtaaatt gactattgta caagtcagcg tagaagccac cttgcgccat cagttcctca
     7741 tagttgcctt gctcgatgat atttccatct ttcatgacca agatcaagtc tgcatttcgg
     7801 atggttgaca agcggtgggc aatgacaaag gatgtgcgtc cttccatcaa acggtccatg
     7861 gctttttgga tcaattcctc tgtccgtgtg tcaacagaag aagtcgcctc atccaaaatc
     7921 aaaagcggtg catccttaag aagggcacga gcaatagtca atagttgttt ttgtcctaca
     7981 gacaaggtca cggtgtcatc caagatggta tcatagccat ctggcaaggt cataataaag
     8041 tggtgaattc ccacagcctt actagcttcc atcattcgtt catcactaat ccctatttga
     8101 ttatagatga gattgtctcg aatagttcct tcaaagagcc aggtatcctg caagaccatt
     8161 gaaaaggcat catgcacttc tgaacgcgtc atagccttgg tatccacacc atcaatgtga
     8221 atacttccct tatcaatctc atagaatttc atcaaaagat tgacaatggt tgtcttacca
     8281 gtcccagtcg gcccaacaat ggcaaccttt tgaccagcat gagctgtcgc agagaagtca
     8341 tagtcttgaa cattgacacc gtccaccaga atttctcctg ctgacacgtc gtagaaacgt
     8401 ggaatcagat tgaccagagt tgatttacca gaacctgttg acccaataaa ggccactgtt
     8461 tgaccagttt ctgctttaaa gctaacatgt tcaataactg cctccgaatt tgccgcatag
     8521 cggaaggtca catccttaaa ctcgacctga cctttgaagt tttcatcagt cagctgcact
     8581 tgaacagggt tttggataga agaatgcaaa tctaaaactt gattaatccg cttagcagag
     8641 accatagttc ggggaagaac gatgaagagt gctcccatga gaaggaagcc catgacaacc
     8701 tacatggcat aagacatgaa aacaatcatg tcactaaaga gaggcagacg cgctatcgaa
     8761 gcagcgtcgt taatcacata ggccccaatc cagtaaatcg ctacactcaa accacttgaa
     8821 atccccatca tgataggatt caaaatagcc ataagacggt tgacaaacaa attcaaacgg
     8881 gtcaattcat catttactgc tgcaaatttt tcattttgat aatcctctgc attgtaggca
     8941 cgaacgacac gaatacctgt taaactctca cgagtgatac tgttcagttt atctgtcaac
     9001 ccctgaatca aggactgttt tggaaaggct agcgtcatca aaacggtcgt catcaggacg
     9061 ttgacaatca ctaccacaag tacggcccag agtcagtatt ctgaatgacc taaaatcttc
     9121 ccaatagccc agatagccat aattggacca cgcgttacca cttgcaagcc catagtaatc
     9181 aacatttgaa cttgagtaat gtcattggta gtacgcgtca agaggctagg aattgaaaat
     9241 ttcttaatct ctgtctgcga gtaatccaaa actcggttaa aaatatcact tctcagccta
     9301 ctagtataag aagccgccac tcgggatgca aaaaatccaa ctgcaactac ggacaaaaag
     9361 gcaagaaaga gcattcccat catcatgctt gccggctgcc acaactcatc taaattagtt
     9421 tcttgactac ctagcaaatc cgtaattttc gagatatagg tcggcacttc caactctaga
     9481 tagaccgaaa agcaagtaaa gagaatggct agtaaaatca tcccccattc ttttctacta
     9541 attcttttgg ttaatttctt tattctctcc tcctattccc ttgatatttt gcctgtagtt
     9601 gaccgagaac tttctcaaaa atcagtaatt catcttcatc aatgtcttcc atcaactgct
     9661 tgtctatgcg ttcaaaaaaa gccttaacct gttgcatctg agaacgtgct ttgtccgtca
     9721 gacgaacaaa cttagcccgc ttatcaacag gactcgcctc caattccacc aaaccatttt
     9781 gcactatacg cttaaccaga ttactagcaa cagacttggt aatattgagt tcctgctcga
     9841 tatctttaat caagaccaag tcttggtttt tctagcgatt atccaaaaaa cgcacaacct
     9901 gaccttgcgg cccacccata aattcaatgc cgcaacgttt ggcttccttt tgcaccatca
     9961 ggtgaatttg atgaccaaaa cgcttaaaga ctaacatcgg tttatccata atctccccct
    10021 tctaaataaa aatagttctc tggagaataa ttaaatttct atgagaacta ttttcttgat
    10081 taaaaaaatc ccaagtgatt ttctcactta ggatcatgtt ctataggtta aattaaaacc
    10141 catctacgtt cgtataaatc ttttggacgt cttcgtcgtc ttcaagaacg ctgtaaagtt
    10201 tttcaaaggt ttcaaggtct tcgcctgaca attccacttc tgactgagga atcatttcca
    10261 attcagtcac ttggaattct tcaataccag actcacggag agcaacgata gccttgtgaa
    10321 ggtcagttgg cgctgtgtaa actgtgattg taccttcttg tgcttctacg tcatccacat
    10381 ccacatccgc ttcgagcaat tgctcaaaga ctgcgtctgc atcttcacct ccaaatacaa
    10441 taacaccttt gttgtcaaag aggtaagaaa cagaacctga agcgcccatg tttccgccgt
    10501 ttttaccaaa ggctgcacgg acattggctg ctgtacggtt gacgttagaa gtcaaagtat
    10561 ccacaattag catagagcca tttggcccaa aaccttcgta acgtccttct gtaaaggttt
    10621 cgtctgtgtt tcctttggct ttatcaatcg ctttatcgat aatgtgtttt ggcacttggg
    10681 cttgtttagc acggtcgata acgaatttca aagctgagtt tgattctgga tctggatcac
    10741 cttttttagc tgctacatag atttctacac caaattttgc atatacctta gagttagctc
    10801 catctttagc cgttttcttg gctacgatat tggcccattt acgtcccatt aggaatctcc
    10861 ttttttcaca ttttaatctt tattattata acacaagttt ttttgatttt cactagagga
    10921 aatggatttt attagcaaat caagctagga tagcacttta cctgctaaga tggtcttacc
    10981 tttctatctt tatcaacaga cactcatcca cattcaaaaa acaaactaga ccattatctg
    11041 caaatagaaa gtttcagcca agtttgacaa agtcagctca aattactgtt tgaagtttgt
    11101 agatataagc gacaaaaaca atcatactgc accttttgtt gacagtctac tccagacata
    11161 tcatagttca agtaaatact ttgaaattca acagttctta taggcgctat tgtattctaa
    11221 gaaatcaata gaagagtttc taagcaaacc tctaatactc aataaaaatc aaagagcaaa
    11281 ccagaaagct agccgcaggt tgctcaaaac actgttttga ggttgcggat ggggctgaca
    11341 tggtttgaag agattttcga agagtataat ttacgtgttc ccaagatgga gaagttagac
    11401 tagtacactg gcacttctaa accattgcta gcaattgatt tgttcatatt taatttcatt
    11461 ttttccataa atgggtatta gatataaaca gcaaaatatt tccgatacgt gtcgttcttg
    11521 aatttccaat catctaaaac aagtaaagga taatcaatcc cctgtatatc aaggaattgg
    11581 ctaccctttt tactttttta cacattctgt ttgatagatt cattttaaca tcacgagcat
    11641 actccaatgg aaatcgctag gcaagagata aactttcaga tatccgcaga gagatcatcg
    11701 cctctttttg tcgcaagcat tctcctctcc tagtcatttt ctaccttatc ttctacctga
    11761 ggatagagag ttgttcccca aatagaaatc gtccgcttac gcactagtgg caaatcggtt
    11821 ttttcataaa ccgtacgcca ccattcccag gcaagcccgg tacactctct aattttgaca
    11881 gagagattac gaacattccc ttttaaagga atactagtgg taaagtgagc cgttaaatcc
    11941 tgcccatttc tgtcccaagc cttaggagtc aagacttcct taccttgatg atcataggat
    12001 aattcattcc aagtaatata atattgggca acataggcac cactatgatc cagcagtaaa
    12061 tctccgtttc tgtaagctgt aaccttagtc tcaacatagt ctgtactatt ttgaaaggtc
    12121 gcaactacat tgtcacgtaa aaaagaagtt gtataggaaa tcggcaagcc tggatgatct
    12181 gctgtaaagc gactgccttc ttgaatcaag tcctctacca tatccacctt gcctgttaca
    12241 actcgggcac ccgaacttgg gtcgccccct aaaataaccg ccttcacttc tgtattgtcc
    12301 aaaatctgtt tccactctgt ctgaggagct accttgactc cttttatcaa agcttcaaaa
    12361 gcagcctcta cttcatcact cttactcgtg gtttccaact tgagatagac ttggcgccca
    12421 taagcaacac tcgaaatata gaccaaagga cgctctgcag aaattcctct ctgttttaaa
    12481 tcctctaccg ttacagtatc ttgaaacaca tctcctggat ttttaacagc atctacgctg
    12541 actgtataat aaatctgctt aaaattaaca atctgaatct gcttttcgcc cgaatggaca
    12601 gagttaaaat caatatcaag agaattccct gtcttttcaa agtcagaacc aaacttgacc
    12661 ttgagttgtt ccatgctgtg agccgtgatt ttttcatact gcattctagc tgggacatta
    12721 ttgacctgac cataatcttg atgccactta gccaacaaat cgtttaccgc tccgcgaaca
    12781 cttgaattgc tggggtcttc cacttggaga aagctatcgc tacttgccaa accaggcaaa
    12841 tcaatactat aagtcatcgg agcacgatcg accgcaagaa gagtgggatt attctctaac
    12901 aaggtctcat ccactacgag aagtgctcca ggatagaggc gactgtcgtt ggtagctgtt
    12961 acagaaatat cacttgtatt tgtcgacaag ctccgcttct ttctttcgat aacaacaaac
    13021 tcatcgggta gctgattacc ctctttgatg aaacgatttt caatactttc tccctgatgg
    13081 gtcaagagtt tctttttatc gtaattcata gctagtataa agtcatttac tgctttattt
    13141 gccatcttct acctcctaat aagttcctgg attgagttgc ataaactcag acttgttcag
    13201 cgaaatcagc cgtggttgga ctaagtaatc caaaatttcc tcgtacaatt cttctgagac
    13261 attgcgtcgc cgtctggcta gataagaagt cggaatgacc gtattatcca acataaatac
    13321 cttatctaag tcaatcaagg ttggtcttgt aaaaggatta cgagctagat ccggctcttc
    13381 tatcataaag ttcttgacca aacgtctggt caagagagct ggtttgaagg tctgattttt
    13441 aaccaactct ttgtttttag tcatgctgtt gtcaatacag atatacatat gattcttcac
    13501 agccaaatcg ctactaatag tcggaaaagg caaataaaga gctacaacat ctcctctctt
    13561 aatcaagcaa gagcaccccc ttttctccta atgtaacata gacaggattg accaagtctt
    13621 ctgattgact cagaatttcc aaagtttgag tttggcgcgc tgtcaattta gtagcatctt
    13681 gtctcttcaa tacaaaatgc ttgtcgccaa taaccttgac aatataatcc ttctccaaag
    13741 ctgactggta aatccacatc agatgttgtc tgtcctgaga actcaagaga gaaggatttt
    13801 caagcctccc gatagtctga taaaaatcaa aaacaggagc taactcctgc caatctgatt
    13861 ggctagttgt caaggctaga aaaagggctt tgcgagctga tacttcttgg ttagccttga
    13921 gagttacttt cccctccaag ttttttagaa atcgggaaac tccagaaagc aaatttttct
    13981 ctaactgcga gaaataaaaa cctttcgttc ctagacataa gtctttcatg tcgctttctc
    14041 tagcaaataa gagctcaaac atttgatagt aaaagaaaaa tatctggcac tgggtcgcgc
    14101 tcatcttttc cttatcggct tcttttttta accagagcaa gggcgacagg tagctggatt
    14161 gagacatttc ctctacctcc tactcttttt taactggagc atctgcacta gctgccactt
    14221 cttttgactg gatactttcc cactggttaa tctcctctga gataagacct tcgcatgtct
    14281 tgacaaatag ggcaaaagcc ttggtctttc ctgcatattt ctccgtttgg cattgataga
    14341 ggaatttttc tttctccagg agttgcgcag ttttttggta agaaatccaa ttttcctttg
    14401 cattatacaa attgataatc ccctcacaca gcaagccgag actggataag gcaaccgaaa
    14461 tcaaacggta gcgatcacct ggcataggaa tagcacaaaa gacagctatg aggaaacctg
    14521 ccacgatttc tgttattttt aataccttat agcgcctacg atgttgaacg cttttcttta
    14581 aaaaatgagc tatctgtacg tctaatcgct ctgtcaggta catttcttct ggcgtcatat
    14641 tcgtaactcc tttcatttac tttgataatc atagtataac atatttgaat atcaaagtat
    14701 agtaaaaact ggactataac ttattagact tcctgcgaaa caaaacatgg tatagtagtt
    14761 ctatgaat
//
LOCUS       DBERPV010000040        14419 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.40, whole genome shotgun sequence.
ACCESSION   DBERPV010000040 DBERPV010000000
VERSION     DBERPV010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14419
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.40"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(135..971)
                     /locus_tag="ACL8C7_001742"
     CDS             complement(135..971)
                     /locus_tag="ACL8C7_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS1395893.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTNLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(984..1613)
                     /locus_tag="ACL8C7_001743"
     CDS             complement(984..1613)
                     /locus_tag="ACL8C7_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS1395894.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(1623..2264)
                     /locus_tag="ACL8C7_001744"
     CDS             complement(1623..2264)
                     /locus_tag="ACL8C7_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS1395895.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(2410..3639)
                     /locus_tag="ACL8C7_001745"
     CDS             complement(2410..3639)
                     /locus_tag="ACL8C7_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HGS1395896.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILELQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEYYQELSGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(3629..4795)
                     /locus_tag="ACL8C7_001746"
     CDS             complement(3629..4795)
                     /locus_tag="ACL8C7_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HGS1395897.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            4939..5952
                     /locus_tag="ACL8C7_001747"
     CDS             4939..5952
                     /locus_tag="ACL8C7_001747"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HGS1395898.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(5997..6416)
                     /locus_tag="ACL8C7_001748"
     CDS             complement(5997..6416)
                     /locus_tag="ACL8C7_001748"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HGS1395899.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(6427..7833)
                     /gene="atpD"
                     /locus_tag="ACL8C7_001749"
     CDS             complement(6427..7833)
                     /gene="atpD"
                     /locus_tag="ACL8C7_001749"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HGS1395900.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(7919..8797)
                     /locus_tag="ACL8C7_001750"
     CDS             complement(7919..8797)
                     /locus_tag="ACL8C7_001750"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HGS1395901.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLSDQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(8813..10318)
                     /gene="atpA"
                     /locus_tag="ACL8C7_001751"
     CDS             complement(8813..10318)
                     /gene="atpA"
                     /locus_tag="ACL8C7_001751"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HGS1395902.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(10333..10869)
                     /locus_tag="ACL8C7_001752"
     CDS             complement(10333..10869)
                     /locus_tag="ACL8C7_001752"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HGS1395903.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(10869..11363)
                     /gene="atpF"
                     /locus_tag="ACL8C7_001753"
     CDS             complement(10869..11363)
                     /gene="atpF"
                     /locus_tag="ACL8C7_001753"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HGS1395904.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(11377..12093)
                     /gene="atpB"
                     /locus_tag="ACL8C7_001754"
     CDS             complement(11377..12093)
                     /gene="atpB"
                     /locus_tag="ACL8C7_001754"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HGS1395905.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKIQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(12128..12328)
                     /locus_tag="ACL8C7_001755"
     CDS             complement(12128..12328)
                     /locus_tag="ACL8C7_001755"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HGS1395906.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(12403..13338)
                     /locus_tag="ACL8C7_001756"
                     /pseudo
     CDS             complement(12403..13338)
                     /locus_tag="ACL8C7_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(13824..14222)
                     /locus_tag="ACL8C7_001757"
     CDS             complement(13824..14222)
                     /locus_tag="ACL8C7_001757"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1395907.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT         4364 a         3167 c         2565 g         4323 t
ORIGIN      
        1 taacaatgtt ttagaaatca cagtgggcta ttccatattc aattatccat attcaatcgc
       61 tattatcgtt ttcctagatt acaaaaaaaa ctacgttttg ctaatcaaaa cgcagtttca
      121 gccactattt tatcttactg tccttctttt acttctttgg ttgctacatc ttctccaaac
      181 catttttggc tgatttcttg gaacttgccg tccttgtaaa gactagaaaa agcttcattt
      241 atcttcttaa ccaagtttgt atcttcctta cgggctccaa ccgcaaaagc ttctgtttct
      301 agtccaactg taaagacatt ataatcgttt aaaacacctt ctgcttctaa ataatagttt
      361 gcatagacac ggtcaatcaa tagaccatca attcgatcgt ttttcaaatc aatcaaggct
      421 tcattaaagg tttggtattg attcgcttcc ttattagcga caatattctt caaaatttct
      481 ggatttgctt caaagtccgc ataaccagat gaaccagctt gagctcctaa tgtctttcca
      541 gtcatatcct ttgcagtcgt gataccagat gatttcttcg taaccaatac ctgctcattc
      601 ttcatatatg agttactgaa agccaccttt tcacggcgtt cgtctgtagc ggaatagcca
      661 ttccaaatca gatcaatcgt tccttttgtc aattcagctt ctttcaaatc ccaatcaatc
      721 ggttgccaat ttaccgtgat tccgtatttt tcaaaaacag ctgtagctaa atcaatatca
      781 aatcctgcat aagaaccatc tttctgagca aatcccattg gaacaaaagt actatcaaat
      841 ccaatagtaa tagacttgtt agactggtac tttgaccaat tatctccact agtttcgcta
      901 gaatttttcc cacaagctac taagaacaaa gcagtcatca gactgactaa tacaagcatc
      961 cattttttca tccatttttc ctcctattta ggttctactt tcaataatac atctgcgata
     1021 ttttcagcaa actgcaaatc atgggtaacc acaatctggg tcatcccaag ttccctattt
     1081 tgcaagatta gcttctccac ttccaaacgt aattctggat ccagggcaga agttggttca
     1141 tcgtagccaa tgatttctgg gtcaatcatc atagcacgcg ccaaagccac ccgctgcttt
     1201 tgcccaccag atagtgagaa aggataggcc tctgcgtgtc ctcctagtcc taactgttcc
     1261 aagagtccac tcgccttctt ctcagcctct tcctgcttca ttcccatggt cttcacaggc
     1321 gataaagtca aattttccag aactgataga tgaggaaata gttgaaaatc ttggaagaca
     1381 aatcccagta gattgcgctt ctgcaattca tccagctcta aaggttgtcc attataaaag
     1441 atttgccctg aatcaatggt ttcaagacct gcaagcatac gtaaaagagt tgtcttacct
     1501 ccaccagaag gtccaacgat agccaggatt tgcttttcag gaatacttag actgaaatta
     1561 gacaggattt gtttgtctcc aaagacttta ttgatatttc gtaattctaa catggcagcc
     1621 tcctatctat aataactata cttcttctca acttttttgg aaataattgt cacaatccca
     1681 atcaaaatca aataaatggc tcctgccaag aacataggaa ctagactagc atcgcggtta
     1741 gcagctgttc gactagccaa gataaggtct gaaattccga gagcatagac caaagaagta
     1801 tccttgacca aactcataac ttcattaaag acactaggaa gaacgatctt ggtcacttgg
     1861 ggcaagataa tatagcgcac tctgtcaaaa gggctaaact tcaagacctt ggcggcctca
     1921 tactgtcctc ttggaatagt gtcaattccc ccacggaaaa tttctgcaaa gtaagctgca
     1981 tagttgagaa caaaggcaat aatagctgca ggaaggcggt ctaaacgaat cccaatactt
     2041 gggagcacat aatagataaa aatcagttgc aagagtaagg gggttcctcg cataacccag
     2101 atgtaaatgt taatcagata atggaggggc ttccaatgga cttgcaaggc aaaggcaatc
     2161 aaaacgccca agggaatcga aaatagcaag accagtgcaa agacctgtac agtcgtgctc
     2221 gcaccattca gtaaactcgg taatatctca aataaataag acatactgca cctcctaaaa
     2281 gtaattgttc ctattatagc atgaataaac aagattacca agtatttttg taaaaagatt
     2341 ctaccatata caaataaaaa ccgtagctat caaaagagat aaactacagt tctatatgtt
     2401 taaacattct tacaatctct caaacagttc ttgcatttgc acatcatctg gaaccagttt
     2461 taagtaagtg tgagcatgga cttttgcttc ttcaaaatgt cccaattcac gcaagagata
     2521 gatatagtgt tccagaaatt ctggattgtc cttcaaatct cctgacaact cttgataata
     2581 ctcataagca gtatccaaat cgtccatttc ttgataagaa cgagcaatca tccacttggt
     2641 caaaagattt tctggctcct cactctgcaa ttctagaata tcctcataac gctcctgctc
     2701 cagataaata gtggctaaac gaagcaagat ttcttctgta tcctcagcgt cttcttttgc
     2761 agtaaggaga taattttctg caccactagc atcatgcaat tcataagaaa attgtgaagc
     2821 agctagcaag aggcgagttt caaagggatt tttctctaat ccttgcttag cgatacgcag
     2881 ggcttcttga acttgatgtt ccttatgtaa agcctgactg tacccatact catagccttc
     2941 aaagtcagga gaaatggtat caagctgctt aaagtagagg gtggcttttt gatattcttc
     3001 ttgatcaaaa taaagactgg ccaactcaaa agctgttaag tcatcgtatt ctaactccag
     3061 ggctttttct aaaaactcag tagccgtttc aaatttccct aactgagcat aggcaaagcc
     3121 aattcgttga taggtggaaa tgcccgtttg ctcataaatc gagcgattat ctaactgggc
     3181 ataggcttga atagccgctt ggtaattttc caactcacta tccaactctg ccaaacccaa
     3241 tatcaagaga gaatcctctg agtaggtcaa ggcctccaat aatttctcac gtgccacatc
     3301 tgtcaaacct tccagctggt aaaggtctgc cttcagagcc aaagacgaga cataccagtc
     3361 actgtcagct tggatttcct caagataggt aaaggcttct tctatttgac catcctcgct
     3421 agcaattgca gctagattaa gatgaacctc tggaaaatcc tctacaattt tcaggtaaat
     3481 ttccttggcc tgaggataga aaccaatccc ttcaagataa gttgccaatt catacagaag
     3541 atcacttgaa tcattttcta aagctttggc gaaataatgc tcagccttag ttaaatcttg
     3601 ctcctccaaa gcctgtaaca tctgttgact attgttcact cttgacttcc tcaccctcta
     3661 attcatatag accactgact accttatacc attcgaaaat ggctgaaatg acaaccttag
     3721 cagaggcata aaccggaata ccaagtaaaa ctccccagat accaaacata gatcctgaag
     3781 ttaacaaaac aaagagaaca ttaatagggt ggatgtttaa ttgacttccc aaaatcaatg
     3841 gagagacaaa acggccttca atagtttgtt ctacgataaa gacaatcact actttcaaaa
     3901 gcatgactgg accagcaatc aaacccaata ctagagcagg aagcatggct agaaagctac
     3961 caagataagg gaccagattt aaaataccag cagtaacccc cagcgtaacc gcatagcgta
     4021 gaccaataat cttgaagaag atgataaaca ttactgctac aataatagcc actgtcactt
     4081 gccctcgaac atagttggac aactgttgat tcacatctga taaaacttgt ccaacaggtt
     4141 ccttcaattt tcttggaatg aattgggtca aatagttacg caagcctttc ccatcacgca
     4201 agagataaaa gagcatgaaa ggaacgataa tcaaggcaac aatcacttga gaagccccgc
     4261 taataaaggc actcacccag ttgactgcct gagatgaaac cttacttgcc aaaactgtag
     4321 cctggctaga aaaattggtc aaaacttgct ctaattgagg tctgaaatca tctggcaggt
     4381 gctgggctac caatccatta acaatcctat ctatatcttc taagtaaaca ggaacgtttc
     4441 ttgcaaaggt caaaacctga cgttgcagat ttggaatggc gactgccaag ccccaaatga
     4501 taaagagagc gatgataaca aagacaatag tgatagctat aacacgatta accttatgct
     4561 tctccatcca atcaacaata ggattcaaca aataatataa caaaccagac aaaatgactg
     4621 gcaacatcac aactgctaaa aagtctaaaa caggtgaaaa tagaaaacta atcttactta
     4681 aaataaaaag attcagtccc aataataagg ttactaaaaa taccgtaatt gccttgttat
     4741 ctaaaaacca cttgaaaaac caagataggc taaaatgttt ctctttttgc tccataaata
     4801 cttcctttct attgttctct cattatacca tttttgaaac aaaataactc ttttttaaag
     4861 tgcttacatc taattggata tctttaattt acttgttttt gtgatataat agtcttatct
     4921 ttacacagag gtatagtaat gaaagaaact gtttattttg gaacttatac acgtcgtact
     4981 tctcaaggga tttacaaggc agactttgat acagaaactg gtcagctttc aaatctagaa
     5041 ctttttgcag ctgagccaag tccaacctac cttgcctttg accagcacca acatttatac
     5101 actgttggta gccaagacga taagggggga attgcagcct atcaaactga cgggactgtg
     5161 ttaaatcatg ttgttgaaga aggagctccc cactgttatg ttgctgtcga tgaaaagcgt
     5221 gatttggttt acgcagctaa ctatcacaag ggacaagtcc ttgtttataa acgccaggaa
     5281 gatggtagtc ttctacttag tgatatggat caacacagtg gccaaggtcc acatgaaaat
     5341 caagcttccc cccatgttca ctatacagat ttaacacctg accactatct agtgacctgc
     5401 gacttgggaa ctgaccaagt catcacctat gacctcgatc aagaaggaaa attatctaag
     5461 ctctatacct atcacagcaa gccaggagca ggctcacgcc atatcatttt ccataaccac
     5521 tataaaatcg cttatctcat ttgtgaactc aatagtacta tcgaagtttt aatctacgat
     5581 ggcgttggcg aatttgaacg tatgcaggtc atttcaactt taccggaagc ttacgaaggc
     5641 tttaatggaa ccgctgctat tcatctctct aaagacggta aatacctcta cgcttctaac
     5701 cgtggccatg attctatcgc agtatatacc atccttgcgg acggtagctt agagttatta
     5761 gaaatcgttc caacgcatgg tcagactcca cgtgattttg atttgacacc cgaccaaaaa
     5821 tttctcattg ttgtccatca agactctgac aatgcaactg tctttaaacg taattgtgac
     5881 aatggtcgtc tagcagaact ctccaacgac ttccatgttc ccgaagcagt ctgcatccgt
     5941 tttgctcctt aaaacaccat aaaaaatgaa cttggtattt tcaagttcat tttttcttat
     6001 agtctatttc cgacattaat acggttaatg gcacgttgca aagcaatctt agcacgacgt
     6061 tcttggtcaa tcaaatgttt gtcttgtgct tcttcaattg cacgttctgc acgaagtttg
     6121 gcacgttctg cacgactgat atcgatatca cgagcacgtt ctgcagagtc agcgacgatt
     6181 gtgatcatat cattggcaat ttcaataacg ccaccgttta ctgcaatcca gttcacgtga
     6241 tctttatcat cgatacgttt tacctttact tcatcaactg ctaaaaccgc aatcatattt
     6301 tcatgtcgtg gcaagatccc catctcacca tccagagttc gaaccgatac atagctggca
     6361 tggtgatcat agacgagacc atctggtgtc acgatctgga cagttaactg agccatagat
     6421 cacctcttaa aatcccattt tttcagcttt tgcaatcaca tcttcgatag aacctacacc
     6481 acggaaggca tcttctggca agtggtcgta tttaccatca aggatttcct taaagccacg
     6541 tacagtttca gcaactggaa cataagaacc tggctgacca gtaaattgtt ccgcaacgtt
     6601 gaagttttgt gacaagaaga actggatacg acgggcgcga gcaaccaagg tcttttcttc
     6661 atcagaaagc tcatccatac caaggatagc aatgatatct tgcaattcat ggtaacgttg
     6721 aaggacacgt tttacttcag cagcaactgc atagtgctct tctccaacga tttcaggtgc
     6781 caaggcacgt gagcttgaag caagtgggtc aacggctggg tagataccca attgtaccaa
     6841 cttacgttcc aagtttgttg ttgaatccaa gtgagcgaag gctgttgctg gcgctgggtc
     6901 agtatagtca tccgctggca catagatagc ctggatagag gttacagaac ccttcttggt
     6961 tgatgtgata cgttcttgca attgacccat ttccgtagca agtgttggtt ggtaaccaac
     7021 ggctgatggc atacgaccca aaagggcaga tacttctgaa ccagcctgag tgaaacggaa
     7081 gatattatcg ataaagagaa gcacgtcttg gccttccaca tcacggaagt attcagcgat
     7141 tgtcaaacca gtaagggcaa cacgcatacg tgctcctggt ggctcattca tctgaccaaa
     7201 gaccatggct gttttctcga taacgcctga ttctttcatt tcccagtaaa ggtcattccc
     7261 ctcacgagta cgttccccaa caccagcaaa tactgaaata ccaccgtgct cttgggcaat
     7321 gttgtgaatc aattcttgga ttaagacagt tttaccaact ccggcaccac cgaaaagtcc
     7381 aactttacca cctttaaggt aaggggcaag aaggtcaata accttgatcc ctgtttcaag
     7441 gatttcagaa gaggtagaca actcatcaaa agttggagct tttttatgaa ttggctgacg
     7501 ctctgcgtct tctgtaaaag gagcttccaa gtcaatggta tctcccaaaa cgttgaagac
     7561 acgtcccaaa gtttctttac ctactggtac agagattgga cgacctgtgt ccaatacttc
     7621 cattccacga gtcaacccat ctgttgattc catggcgata gtacgaacca taccatctcc
     7681 taactccaag gctacttcaa ggacgatttt tgtttttctt tcgtcatttt tgtagacgac
     7741 aagtgcattg ttaatctcag gaagtttttc ccctgctgca aacaaaacgt ctacaacggg
     7801 accgataacc tgagcaattt tacctgaact catctccttc tcctattcta tataagatac
     7861 tgtcggttcc tagctcaact aggtcctaag ttcattttca tacgagctgg actagagcct
     7921 attctaaggc actagcacct gctacgattt ctgtaatttc ttgtgtaatc gccgcctgtc
     7981 tggcacggtt atactgaatt gtcaaatcat tgatgacttt cttagcatta tctgtcgctg
     8041 tttgcatggc tgtcatgccc gcagcattct cagctgtctt ggcatcgata atggcaccgt
     8101 aaatcatact ttctgcaaac tgaggcaaca actgctccag aatttcttct cggctggttt
     8161 ccaattcaaa agtcaagctg tactcttcat ccgcttcatt tggatccaag tcaacaatcg
     8221 gaagcatttg ttccacacgc atttgactgg ttagcgtatt gacatggtgg ttgtagcaaa
     8281 cataaagctc atcaaagagt tcattttggt acatttcaac agtttttgaa ataatcttac
     8341 gaacttgatc aaagctaggt tggtctgaca agccacgtaa ttcataaagt ggttgaatac
     8401 cgcgagcctt aaagaaatca gctcccatcc caccgataca gatcatttca aaacctttac
     8461 cgtctgggtg gtattcttct ttcaactcca taacagcttt caaaatagag gaattataac
     8521 ctccaaccaa accgcggtct gaagtgataa cgatatagcc tgtcttcttc acagaacggc
     8581 taatcaacat cggattagtt gaagcaccag ctccattacc atgaaggata tctgtcaaaa
     8641 gtttacgcac tttctgagcg taaacttgga agttgcgagc agcttcttca gaacgaccta
     8701 gcttagcagc cgataccatt tgcatggcat tagtgatttg actcgtattt tttgttgagg
     8761 cgatttttgt tttaatatca tttagagata ctgccatctg acacctctat tcttattgga
     8821 agctagattg attgagaaac tctgtaatcg cagcatccaa gactgcttct tctggcaagt
     8881 cttttgtatc acgaatggtt tccaaaatct ctggatgttg agcatcaaag aaggcatgga
     8941 actcttcctc gaaacgaaca atatcatcta ctggaacagt atccaagaaa ccatgtgtca
     9001 aagcataaag aatggttact tgtttctcaa caggtaatgg tttgtgaaca ggttgtttca
     9061 agacctcaac ggtacgacgt ccacggttca acttagcctg tgttgctgcg tccaagtcag
     9121 aaccaaactt agtaaaggct tccaactcac ggtatgaagc aaggtcgata cgaagtgtac
     9181 cagcaacctt cttcatggct ttgatttgtg cagaaccacc tacacgagat acagatgaac
     9241 ccgcatcgat ggctggacga atacctgcat tgaagaggcc atcgccaagg aagatttgtc
     9301 catcagtgat agaaatcacg ttggttgcga tataggctga gatatctcct gcttgtgtct
     9361 cgataaatgg tagggctgta attgatccac caccaagttc atcagaaact ttagctgagc
     9421 gctcaagcaa acggctgtgg agatagaaaa catcccctgg gaaggcttca cgacctggag
     9481 gacgacgaag caagagcgac agttcacgat aagctaccgc ttgttttgat agatcatcgt
     9541 atacaatcaa aacatgctta ccttgataca taaattcttc cgccatagca accccagcat
     9601 aaggagctag gaagagcaat ggagatggtt gtgaagcaga ggctgtcaca acgattgtgt
     9661 agtccaaggc accgtactga cgaagtgttt ctacttgcgt acgaactgtt gattcttttt
     9721 gtccaatcgc gacgtagata cagatcatat cttgatcttt ttggttcaag attgtatcaa
     9781 tcgcaatggt tgttttccct gtctgacggt caccgataat caactcacgt tgaccacgac
     9841 caatcggtac aagggcgtca atagctttca aaccagtttg caatggttct gaaacagact
     9901 tacgttgcat aacaccagga gctggtgctt ctactggacg agttttatca gtgtggattt
     9961 ctccaagacc gtcaactgga cgaccaagcg gatccacaac acgaccaatc agactttcac
    10021 ctacagggac ttccatgatt ttccctgtac ggcggattgt atcgccttca cggatatctg
    10081 taaagtcacc taggatgata ataccaacgt ctgttgactc caagttttga gccataccat
    10141 aagagccgtt ttcaaaattc aacaactctc cactcatgac attttcaagg ccgtgagcac
    10201 gcgcgatacc gtccccgata taggttacaa cacctgtttc agtcacatca aaattgggtt
    10261 tgaaattttc aatttgttgc ttaattaaag cgctgatttc ttgtgcgtta attgccaaaa
    10321 gaacaccact ttctatttca aattttcttt aacaacttta agttgttgtt taatactcac
    10381 atcaattgtc ttgtgattgg caaaaatgac aaaaccacca atgagacttt catcgatttg
    10441 ttcttttaca ctccttactt tcagagacat ttttttctca atcaaaggga gcaaacgagt
    10501 cttctgttca tcagttagag gatgagcaga cgtaatcgtc acttcaaatc gatttgtttc
    10561 tttttcaagt cggttcaagc aatctacaag cacatcataa aaaagatttg ctctgtgatt
    10621 gtaggccaga acctggataa agttttgtaa taaaggtgac acagaatctt ggaaaaaagc
    10681 aattgttttt tccttatccg actcgtctac tgccacttgt tttaaaaaag aaggcagacc
    10741 tgttttttca acaacttgct tgatttgagt caagtctgaa aagatacggt cttcttctcc
    10801 tttttcaagt accaattgga caaaaggcat gctgtatttt tcaattacct ttactgtttt
    10861 cttgtccatt aagcttctcc tagctgatcg atatactgat caatgagtgc tttatgggca
    10921 tgactgtcaa ggttttgtga gatgatttta ccagctaagc tgatggtcaa atctgcgacc
    10981 tcacccttaa cactctgtaa agcttctact ttattttgag caatttcttg attggctttt
    11041 tcttttaagt gtcctgcttc tagtttagca tctgctaaga tattagcctt actttgctca
    11101 gctgtttcct ttgcattttc aatgattgtc ttagcttctt tacggctacc agccaattca
    11161 tcttcgcgtt tttgagccaa tacttctgct ttttgacggg cttcttcagc tctgtcaata
    11221 tctgaagcaa ttttttcagc tctttcttcg aaaatgcctg taatattaga ccatgcaaat
    11281 tttttaatca agactagcaa aagaataaaa gagccagtga ttaaaataaa attaccaatt
    11341 aattcaccta ctgttacgtg catcagttac tcctttctat tcctcttcaa tattaatctt
    11401 attccctaaa tacacagatg tcaaaagagt aaaaacataa gcttggatgc aggaaataaa
    11461 gacagaaaat gcagtccaag ccaaattagc tccaaaggct actggatacc aataaatagc
    11521 ttggtgggaa agaagaagta acaaactcgt catgacctct cctgcaaaga tattcccaaa
    11581 aatccgcaaa gccaaagata agaagtttgt aaattcttcc aagatattca tcggtatgac
    11641 aaaaacagga ctcataaaag attttatact ttttttaaat ccacgacgac gaacgctttc
    11701 tatatgtgtc aacaaaatga caagaaaaga taaggttaag tcatactgta aattagcggt
    11761 tggcgaactc caccagttag tcccatcgat cgtttgaatc tttgtcatta agccaaggtt
    11821 attggcaatc accatgaaaa ggaataaaca aaggaaaaag agtgagtaat ctttcatgta
    11881 gcgcgaacca atgttaggtt ctgtaaatcc aataacaaag tcatagacat actcaagtac
    11941 attttgcttt cctttgggtt tcaaggtcat attgcggctt gcccaataaa taaagacaaa
    12001 aataactccc acaatcaaca aagtcatggc taacatagtc agattgaaga taacaggacc
    12061 aatagagatg attggattaa tactttcttc catctaaaat cctccctttt cttctcgttc
    12121 catgtattta tttgataata aatgagaaga caagagttac aaagaaagtt ccttcaataa
    12181 aggcaacacc taaaaacatc aaactacgaa actcagaaag catatctggt tggcgtgcta
    12241 ctgatttaaa cagtccattc atcaataaac cttcaccgac agatacgccc atacaggcaa
    12301 tacataagcc taaaaatgtt aaattcataa caaattctcc tttaaaataa aatttactta
    12361 cttagtgtag tcctaaaatt taaatttgtc aacttttaac cgctattgga agcgtttaat
    12421 aaaaattatt tccattttgc taaatttcaa gttcaagtta gccatccaga agtcttctct
    12481 gggtgacttg taatccaagc attttttagg atagttgtta atccactttt cgatgaatgc
    12541 gacttctttg ggagtcattt tcttggttcc cttaggtaac catctacgaa tgagcctgtt
    12601 gtgattctca ttagttcccc tttcccaaga ggcataggga tgtgcataat aaatgtgctc
    12661 ctcagaaaat acattagaca agcgattgaa ttccgttcca ttatctgccg tgatggaaag
    12721 aatcttgtgt tgttttaaga tgagttttag agcctgattg accacctcag cacttttatt
    12781 tggaatcaat cggatgatct gatgtctact ctttcgatcc gtcaagacaa gcaagcagta
    12841 gtttttcgat ctcgtaagta gaaccgtatc aatctcataa tgcccattct ccaagcgaag
    12901 attgatagct tcaggccgct gtgcgatgga ttgaccagca ggtttaaagt tggtgctagc
    12961 ctgtttctta agcacttttc cttttctagg gtaaagcaga tcctgcttgc ttaaccccaa
    13021 ttttccatga tgaatccaat agtaaatggt tgaaattccc acgttaaccc ctttagccat
    13081 caccatcatt tcaggcgaaa atttttggtt atgatagtgg agaatctttt cctttagttc
    13141 cttggtcaag cttgatttct tgaccgagcg cttgcgattg ttttcataag actgttgagc
    13201 atagtcggca gaataaacct ctttgaagcg cccttttcca agacattttc ggactgtcct
    13261 acgcttgatt ttagtgtgga tagtttgagg agcttttcca agcagagagg taatttctct
    13321 atttgatttc cctttgttcg ccttttgtag tataatggtt ttgcatctct gtgcctttct
    13381 tgtgtttgtg gttgaacaac aagtataaca cagaggtgtt ttcttatgcc tacaagagct
    13441 ttcattattt ccattttctt tcggatttca ctctattctg aaaaacttgt gtatatttac
    13501 tgaagctagc aagtcttacc tgtaaattta atgaaagcaa cacaaaatcc gagaggggaa
    13561 tctcggatta atgtcaattt aaaaagatag agagttttta gtttaaataa attgttttaa
    13621 aatatcaaca acatcacttc ttttcttaac ctgataagcc ttgattccta attttggagc
    13681 tacgattata ttgtcctcaa tatcgtctag aaagacacaa tttctaggtt ataactggta
    13741 tttatcgata gttactcata tacatcagtc cacctccata cttatgtgcg agcctctctt
    13801 tgtattatac ctccatactc accttacaga ttcttttggt aataatatct ttgcctaatg
    13861 tagagatagt cttgcaaaga aaaaacttcc ttgtagccat gtttctgata aaagtccggt
    13921 gcctggaact gataagtatt gacaaaggca aaacaacaat ttcgattctt agcttcactt
    13981 tctgcctgtt gcaatagttt tgaaccgatt ccttgccctc gcagttcctc ttttacaaac
    14041 aaatactcga tttctagcca atttccaaaa gtctctgcta tcaaacccgc aaggagattg
    14101 cccttttcat cttcgacata aagattaagt ggctcacttt cagcctcttc cctttttgaa
    14161 cggttataaa cacgaatcag attccctatt tcttgcgatt tatgtgattc cttattttcc
    14221 aatctaaagt ataatgaaat gaaataaaac atgcgcaaat cgattaagga atttaatcta
    14281 atttctaata atgtcttaga aatcaaagtt tactatttta acttcaatgc actatacatc
    14341 taatactcaa tgaaaatcaa agagcaaact aggaaactag ccgcaggttg ctcaaaacac
    14401 tgttttgagg ttgtagata
//
LOCUS       DBERPV010000041        14306 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.41, whole genome shotgun sequence.
ACCESSION   DBERPV010000041 DBERPV010000000
VERSION     DBERPV010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14306)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14306)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14306
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.41"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..268
                     /locus_tag="ACL8C7_001758"
     CDS             <1..268
                     /locus_tag="ACL8C7_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS1395908.1"
                     /translation="ILADSGYQGTMKIYPQAQTPRKSSKLKPLTAEDKAYNHALSKER
                     SKVENIFAKVKTFKMISTTYRNHRKRFGLRMNLIAGIINHELEF"
     gene            complement(583..2274)
                     /gene="argS"
                     /locus_tag="ACL8C7_001759"
     CDS             complement(583..2274)
                     /gene="argS"
                     /locus_tag="ACL8C7_001759"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HGS1395909.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            2410..2856
                     /gene="argR"
                     /locus_tag="ACL8C7_001760"
     CDS             2410..2856
                     /gene="argR"
                     /locus_tag="ACL8C7_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGS1395910.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            2907..5441
                     /gene="mutS"
                     /locus_tag="ACL8C7_001761"
     CDS             2907..5441
                     /gene="mutS"
                     /locus_tag="ACL8C7_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HGS1395911.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQTLAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            5588..7282
                     /gene="patA"
                     /locus_tag="ACL8C7_001762"
     CDS             5588..7282
                     /gene="patA"
                     /locus_tag="ACL8C7_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HGS1395912.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTDV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     NQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQDGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(7432..7881)
                     /locus_tag="ACL8C7_001763"
                     /pseudo
     CDS             complement(7432..7881)
                     /locus_tag="ACL8C7_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844241.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            8073..9839
                     /gene="patB"
                     /locus_tag="ACL8C7_001764"
     CDS             8073..9839
                     /gene="patB"
                     /locus_tag="ACL8C7_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HGS1395913.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSAGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            9978..10667
                     /locus_tag="ACL8C7_001765"
     CDS             9978..10667
                     /locus_tag="ACL8C7_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HGS1395914.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            10671..10850
                     /locus_tag="ACL8C7_001766"
     CDS             10671..10850
                     /locus_tag="ACL8C7_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395915.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            10837..12186
                     /locus_tag="ACL8C7_001767"
     CDS             10837..12186
                     /locus_tag="ACL8C7_001767"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HGS1395916.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            12310..13770
                     /gene="gltX"
                     /locus_tag="ACL8C7_001768"
     CDS             12310..13770
                     /gene="gltX"
                     /locus_tag="ACL8C7_001768"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HGS1395917.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWIIQKKDGYPTYNFAVAIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQIKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            13784..14218
                     /locus_tag="ACL8C7_001769"
     CDS             13784..14218
                     /locus_tag="ACL8C7_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGS1395918.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGKERASKFNER"
BASE COUNT         4212 a         2764 c         3208 g         4122 t
ORIGIN      
        1 aatcttggct gacagtggtt atcaagggac catgaagata tatcctcaag cacaaactcc
       61 acgtaaatcc agcaaactca agccgctaac agctgaagat aaagcctata accatgcgct
      121 atccaaggag agaagcaagg tcgagaacat ctttgccaaa gtaaaaacgt ttaaaatgat
      181 ttcaacaacc tatcgaaatc atcgtaaacg cttcggatta cgaatgaatt tgattgctgg
      241 tattatcaat catgaactag aattctagtt ttgcaggaag tctattattt ggttaggtga
      301 attagtgaag cgtttaggca agtgtctctg gttacgacgt catggcctct aaatcgatta
      361 tatttagggg tcatgactag tgaagcagtt agctagttcg catataagcg gctagcgtct
      421 aacaattagg aactttagtt ccaataactt taagattacg acgttttagg acataaatcg
      481 atcatattta tgtcctaaaa ctagtgaagc gcctagccaa agtccgaata ggatttggcg
      541 ttagttactt agattgcttt gcaatcaagt aactttggcg atttacatct tctctggcgc
      601 ttctactcca agcaagcgaa gggcttcttt gagaacgact gcggttgcgt agctgagggc
      661 tagacggctg tcgcgttctg ggctttcatc caagatacgt gtatgtgcat agtatttgtt
      721 aaaggattga gccaggctaa ttgcaaattt agcaatgata gaaggttcaa agttatctgc
      781 cgcacggttg ataatacgtg ggaagtcttg aatgagttta atgatttccc agctttcagt
      841 atcattcaag ctatagttgc cagctgtttc tggtttgaaa tcggctttgc gtaggataga
      901 ttggatacga gcgtaggcat attgaacgta aggtccagtt tcaccctcga aggataccat
      961 agcttctagg tcgaagtcgt atccatttgt acggtcggtt ttgaggtcat agaatttaat
     1021 ggctccaacc ccaacagcat gtgctacttg gtctttgttt tctagttcag gatttttagc
     1081 ctcgatttgg accttggcac ggctaacagc ctctgcaaca gtaggctcta gcaagatgac
     1141 attcccttta cgagtagaga gcttcttccc ttcttttgta accagaccaa aaggaacgtg
     1201 ggtaatgtcg tcactccaat cgtagcccat ctcttgcaag acagctttga gctgtttaaa
     1261 gtgggcagat tgttcttgac caacgacata gatagattta gcaaattggt attcgttttt
     1321 acggtagagg gctgcagcca agtcacgtgt gatatagaga gttgcaccat cagacttctt
     1381 gatgagggct ggatgttcaa ttccgtattt ctcaagattg acaacttggg caccttctga
     1441 ttcaagaagt agtccttttt cagaaagaat gtctacaact gcatccatct tatcattgta
     1501 gaaggcttct ccgttatagc tgtcaaattc aaccttcaat tcattgtaaa ggcggttaaa
     1561 ttccactaaa ctttcatcgc ggaaccattg ccaaagagcg agagcttcct catctccatt
     1621 ttcaagttta cggaaccatt cgcgcgcttc ttcatccaag ctagggtcat tttcagcttc
     1681 agcgttgatg cggacataga gtttaaggag ttcatcgatt ggatgagctt ttacagcttc
     1741 ttcgtcgccc cattttttgt aggcaacaat caacatccca aattgtttac cccagtctcc
     1801 caaatggttg accttgaccg tttgataacc gattttttgg aaaatatgtg acaagctatc
     1861 tccgataaca gttgaacgca ggtggccaat agaaaatggt ttagcgatat tcggactaga
     1921 catgtcgata acaacatttt cttgtttgcc aatattttgg tcagcatagt gttctttttc
     1981 agtggtaaca gcttgcaata cttgagcaga aatggcagat ttatcaagga aaaagttaac
     2041 gtaaggtcct gttgcgacaa ctttttcaaa ggcttggctg ttcatttttt cagccagttc
     2101 agccgcaatc atttgtggtg ctttacgttc gacttttgca agagaaaaag cagggaaagc
     2161 aatgtctccc atttctgagt ttttaggggt ttccagtaac tttaaaatag cctcttggtc
     2221 caggctatca atgatgctag ataattcgct agcaatcaat tcttttgtat tcattaagag
     2281 ctcctttttg gacttttcta ctattttatc acaattttaa agaaagaaga aaaaattttt
     2341 gaaatctcct gtttttttgg tataatatgg ttataaatat agttataaat atgcacgcaa
     2401 gaggatttta tgagaaaaag agatcgtcat cagttaataa aaaaaatgat tactgaggag
     2461 aaattaagta cacaaaaaga aattcaagat cggttggagg cgcacaatgt ttgtgtgacg
     2521 cagacaacct tgtctcgtga tttgcgcgaa atcggcttga ccaaggtcaa gaaaaatgat
     2581 atggtgtatt atgtactagt aaatgagaca gaaaagattg atttggtgga atttttgtct
     2641 catcatttag aaggtgttgc aagagcagag tttaccttgg tgcttcatac caaattggga
     2701 gaagcctctg ttttggcaaa tattgtagat gtaaataagg atgaatggat tttaggaaca
     2761 gttgctggtg ccaatacctt attggttatt tgtcgagatc agcacgttgc caaactcatg
     2821 gaagatcgtt tgctagattt gatgaaagat aagtaaggtc ttgggagttg ctctcaagac
     2881 ttatttttga aaaggagaga cagaaaatgg cgatagaaaa gctatcaccc ggcatgcaac
     2941 agtatgtgga tattaaaaag caatatccag atgctttttt actctttcgg atgggtgatt
     3001 tttatgaatt attttatgag gatgcggtca atgctgcgca gattctggaa atttccttaa
     3061 cgagtcgcaa caagaatgcc gacaatccga tccctatggc gggtgttccc tatcattctg
     3121 cccaacagta tatcgatgtc ttgattgagc agggttataa ggtggctatc gcagagcaga
     3181 tggaagatcc taaacaagca gttggggttg ttaaacgaga ggttgttcag gtcattacgc
     3241 cagggacagt ggtcgatagc agtaagccgg acagtcagaa taattttttg gtttccatag
     3301 accgcgaagg caatcaattt ggcctagctt atatggattt ggtgacgggt gacttttatg
     3361 tgacaggtct tttggatttc acgctggttt gtggggaaat ccgtaacctc aaggctcgag
     3421 aagtggtgtt gggttatgac ttgtctgagg aagaagaaca aatcctcagc cgccagatga
     3481 atctggtact ctcttatgaa aaagaaagct ttgaagacct tcatttattg gatttgcgat
     3541 tggcaacggt ggagcaaacg gcatctagta agctgctcca gtatgttcat cggactcaga
     3601 tgagggaatt gaaccacctc aaacctgtta tccgctacga aattaaggat ttcttgcaga
     3661 tggattatgc gaccaaggct agtctggatt tggttgagaa tgctcgctca ggtaagaaac
     3721 aaggcagtct tttctggctt ttggatgaaa ccaaaacggc tatggggatg cgtctcttgc
     3781 gttcttggat tcatcgcccc ttgattgata aggaacgaat cgtccaacgt caagaagtag
     3841 tgcaggtctt tctcgaccat ttctttgagc gtagtgactt gacagacagt ctcaagggtg
     3901 tttatgacat tgagcgcttg gctagtcgtg tttcttttgg caaaaccaat ccaaaggatc
     3961 tcttgcagtt ggcgactacc ttgtctagtg tgccacggat tcgtgcgatt ttagaaggga
     4021 tggagcaacc tactctagcc tatctcatcg cacaactgga tgcaatccct gagttggaga
     4081 gtttgattag cgcagcgatt gctcctgaag ctcctcatgt gattacagat gggggaatta
     4141 tccggactgg atttgatgag actttagaca agtatcgttg cgttctcaga gaagggacta
     4201 gctggattgc tgagattgag gctaaggagc gagaaaactc tggtatcagc acgctcaaga
     4261 ttgactacaa taaaaaggat ggctactatt ttcatgtgac caattcgcaa ctaggaaatg
     4321 tgccagccca cttttttcgc aaggcgacgc tgaaaaactc agaacgcttt ggaaccgaag
     4381 aattagcccg tatcgaggga gatatgcttg aggcgcgtga gaagtcagcc aacctcgaat
     4441 acgaaatatt tatgcgcatt cgtgaagagg tcggcaagta catccagcgt ttacaaactc
     4501 tagcccaagg aattgcgacg gttgatgtct tacagagtct ggcggttgtg gctgaaaccc
     4561 agcatttgat tcgacctgag tttggtgacg attcacaaat tgatatccgg aaagggcgcc
     4621 atgctgtcgt tgaaaaggtt atgggggctc agacctatat tccaaatacg attcagatgg
     4681 cagaagatac cagtattcaa ctggttacag ggccaaacat gagtgggaag tctacctata
     4741 tgcgtcagtt agccatgacg gcggttatgg cccagctggg ttcctatgtt cctgctgaaa
     4801 gcgcccattt accgattttt gatgcgattt ttacccgtat cggagcagca gatgacttgg
     4861 tttcgggtca gtcaaccttt atggtggaga tgatggaggc caataatgcc atttcgcatg
     4921 cgaccaagaa ctctctcatt ctctttgatg aattgggacg tggaactgca acttatgacg
     4981 ggatggctct tgctcagtcc atcatcgaat atatccatga gcacatcgga gctaagaccc
     5041 tctttgcgac ccactaccat gagttgacta gtctggagtc tagtttacaa cacttggtca
     5101 atgtccacgt ggcaactttg gagcaggatg ggcaggtcac cttccttcac aagattgaac
     5161 cgggaccagc tgataaatcc tacggtatcc atgttgccaa gattgctggc ttgccagcag
     5221 accttttagc aagggcggat aagattttga ctcagctaga gaatcaagga acagagagtc
     5281 ctcctcccat gagacaaact agtgctgtca ctgaacagat ttcactcttt gatagggcag
     5341 aagagcatcc tatcctagca gaattagcta aactggatgt gtataatatg acacctatgc
     5401 aggttatgaa tgtcttagta gagttaaaac agaaactata aaaccaagac tcactagtta
     5461 atctagctgt atcaaggaga cttctttgac aattctccac ttttttgcta gaataacatc
     5521 acacaaacag aatgaaaagg agctgacgca ttgtcgctcc cttttgtcta ttttttaagg
     5581 agaaagtatg ctgattcaga aaataaaaac ctacaagtgg caggccctgg cttcgctcct
     5641 gatgacaggc ttgatggttg ctagttcact tctgcaaccg cgttatctgc aggaagtctt
     5701 aggcgccctc cttactggga aatatgaagc tatttatagt atcggggctt ggttgattgg
     5761 tgtggccgta gtcggtctag ttgctggtgg actcaatgtt gtcctcgcag cctatattgc
     5821 ccaaggagtt tcatccgacc ttcgggagga tgccttccgt aaaattcaaa ccttttctta
     5881 tgctgatatt gaacaattta atgcgggaaa tctagtcgtt cgaatgacaa atgatatcaa
     5941 ccagattcag aacgttgtca tgatgacctt ccaaattctt ttcagacttc ccctcttgtt
     6001 catcggttcg tttatcctag cggttcaaac cttaccttct ctgtggtggg tgattgttct
     6061 catggtagtc ttgatttttg gtttgactgc tgtcatgatg ggaatgatgg ggcctcgttt
     6121 tgctaaattt caaacccttc ttgagcgcat caatgccatt gccaaggaaa atttacgtgg
     6181 cgttcgtgtg gtcaagtcct ttgtccaaga aaaagagcaa tttgctaagt ttacagatgt
     6241 ctcagacgag cttcttggtc aaaaccttta cattggttat gccttttcag tagtggaacc
     6301 ctttatgatg ttggttggtt acggggcggt cttcctctct atttggctgg tcgcgggaat
     6361 ggttcagtcg gatccgtctg ttgttggttc catcgcttct tttgttaatt acctaaacca
     6421 gattatcttt accattgtta tggttggatt tttgggaaat tctgtcagcc gtgccatgat
     6481 ttccatgcgt cgtattcgag aaattcttga cgcagagcca gctatgacct tcaaggatat
     6541 cccagatgaa gagttggttg gaagccttag ctttgaaaat gtgaccttta cctatccaat
     6601 ggacaaggaa ccgatgctga aagatgtgag ctttactatt gaacctggtc aaatggttgg
     6661 tgtagttgga gcgactggtg caggaaagtc aactttggct caattgattc cacgtctctt
     6721 tgatccacag gacggggcca ttaaaatcgg tggcaaggat attcgagaag tgagtgaagg
     6781 aaccctgcgt aaaacagttt ccatcgttct ccaacgtgcc attcttttta gtggaacgat
     6841 tgcagataac ttgagacagg ggaagggaaa tgctactcta tttgaaatgg agcgcgcagc
     6901 caatattgcc caggctagtg aattcattca tcgtatggag aaaacctttg aaagtccagt
     6961 tgaagaacgg ggaaccaatt tctctggtgg acaaaaacaa aggatgtcga ttgcgcgtgg
     7021 gattgtcagc aatccacgta ttctgatttt tgatgattcg acctcagcct tggatgccaa
     7081 atcagagcgc ttggtgcaag aagctttgaa taaggacttg aagggtacga caaccattat
     7141 tattgctcaa aaaattagct cggttgtcca tgcagacaag atcttggttc taaatcaagg
     7201 acgattgatt ggtcaaggca cgcatgcaga cttggttgcc aacaatgccg tttaccgtga
     7261 aatctatgaa acacagaaat gaaagacaaa ctataagaaa agtcaatagt tttatctaaa
     7321 ctatttctta tttcaatttg atgatttggc gatgatttta gagcacggca aaaagccctt
     7381 gaaaaagtcc attttttcaa aggtaatcct gtgttgattt cagaaattac atcacttttt
     7441 gttcgtcaaa tggcagctct tttttaggat ataaaacagg gttcggataa gtttttttgc
     7501 aaggtggatg atggctacat tgtaatgttt tccttattct aacttagtct taagataggt
     7561 cttgaaagca agtgaaaagc gagggcatgc tttggcagct tgtatgagta cctaccgcag
     7621 atgaggggaa ccccgtttga ccattcttcc agctaaatca atctgacctg actgataaat
     7681 agaagaatcc agtccagcga aagcttgtaa ttgagcaaga ttatcaaagg catgaatatt
     7741 tcgaatctcg gctaaaatga ccgcccctaa acgattccca atcccagtaa ccgtcgtgat
     7801 gatcgagttg aactcagcca tcaagtcatt gacacatgtt tccgccttgt caatgagcct
     7861 cttgtaatgt ttgatgtttt cattacacga gataaaacgt ctatgcgtta tcaaactcat
     7921 taccaattaa aacaaaaagc tgtggttaga tcctttcgga aattgtcaag cgattggagg
     7981 aaatgaacta atccacagcg gcttattcca agtataccac ttgggctttg gcagtagcta
     8041 actgcgctaa atataatata aggaggagta aaatgaagac agttcaattt ttttggcatt
     8101 attttaaggt ctacaagttc tcatttgtag ttgtcatcct gatgattgtt ctggcgactt
     8161 ttgcccaagc cctctttcca gtcttttctg gacaagcggt gacgcagcta gccaatttag
     8221 ttcaagctta tcaaaatggc aatccagaac ttgtatggca aagcctatca ggaatcatgg
     8281 tcaatcttgg cctgctggtt ttggttctat ttatctctag tgtaatatac atgtgtctca
     8341 tgacgcgcgt gattgcagaa tcgaccaacg agatgcgcaa aggtctcttt ggtaagcttg
     8401 ctcagttgac ggtttctttc tttgaccgtc gacaagatgg cgatatcctg tctcatttta
     8461 ccagtgattt ggataatatc ctccaagcct ttaacgaaag cttgattcag gtcatgagca
     8521 atattgtttt atacattggt ctgattcttg tcatgttttc gagaaatgtg acgctggctc
     8581 tcatcaccat tgccagcacc ccattggctt tccttatgct gattttcatc gtgaaaatgg
     8641 cacgtaaata caccaacctc cagcagaaag aggtagggaa gctcaacgcc tatatggatg
     8701 agagcatctc aggccaaaaa gccgtgattg tgcaaggaat tcaagaggat atgatggcag
     8761 gatttcttga acaaaatgag cgcgtgcgca aggcaacctt taaaggaaga atgttctcag
     8821 gaattctttt ccctgtcatg aatgggatga gcctgattaa tacagccatc gtcatctttg
     8881 ctggttcggc tgtacttttg aatgataagt ctattgaaac aagtacagcc ctaggtttga
     8941 ttgttatgtt tgcacaattt tcacagcagt actaccagcc tattatccaa gttgcagcga
     9001 gttggggaag ccttcagttg gcctttactg gagctgaacg aattcaggaa atgtttgatg
     9061 cagaggagga aatccgacct gaaaaggctc caaccttcac taagttgcaa gaaagtgttg
     9121 aaatcagtca tatcgatttt tcatacttgc ctgataaacc tattttgaaa gatgtcagca
     9181 tttctgcccc taaaggccag atgacagcag ttgttgggcc gacaggttca ggaaaaacga
     9241 ctattatgaa cctcatcaat cgcttttatg atgttgatgc tggtggtatt tattttgatg
     9301 gtaaagacat tcgtggctat gacttagata gtcttagaag caaggtggga attgtattgc
     9361 aagattcggt cttgtttagc ggaacgattc gagacaatat ccgatttggt gtgccagatg
     9421 ctagtcagga aatggttgag gtagcagcaa aagcaaccca cattcacgac tatatcgaaa
     9481 gtttgcctga taagtacgat actcttattg atgatgacca gagcatcttt tcagcagggc
     9541 agaagcaatt gatttcaatc gctcgaaccc tgatgacaga tccagaagtt ctcattctcg
     9601 atgaagcaac ttcaaacgta gatacggtga cagaaagcaa gattcaacat gccatggagg
     9661 tggttgtagc aggtagaact agtttcgtca ttgcccaccg cttgaaaacc attctcaatg
     9721 cagatcagat tattgtcctt aaagatggag aagtcattga acgtggtaac caccatgaac
     9781 ttttgaagct aggtggcttt tattcagaac tctatcacaa tcaatttgtt ttcgaataag
     9841 aaagaagttg tcctatgtgg gcagcttttt cttgtccata aaaaatgttt atcacagcct
     9901 taaaaaaaac atattagacg aaagtcattt tgagtgatat gataggacta tcgttagcat
     9961 tcgaaaggag aggcatcatg gctagaacgg ttgtaggagt tgctgcaaat ctatgtcccg
    10021 tagacgcaga aggcaaaatc attcattcat ctgtatcttg tagattcgca gagatcattc
    10081 gtcaagtcgg tggtctccct ttagtcattc ctgttggtga tgagtcagtt gtacgtgatt
    10141 atgtggaaat gattgacaaa ctcattttga caggaggcca aaatgttcat cctcagtttt
    10201 atggagagaa aaagaccgtc gagagcgatg attacaatct ggtccgtgac gaatttgaat
    10261 tggcactctt gaaggaagcg cttcgtcaga ataaaccaat tatggcaatc tgtcgcggtg
    10321 tccaacttgt caatgttgcc tttggtggaa ccctcaatca agaaatcgaa ggtcactggc
    10381 aaggactacc tttcgggaca tctcactcta ttgagacagt agaaggaagc gtggtggcta
    10441 agctatttgg gaaagaaagt caggtcaact cagtccatcg tcaaagcatt aaagatttgg
    10501 cacctaattt ccgtgtaact gctattgatt caagagacca aactattgaa gcgattgagt
    10561 ctatcgacga gcaccgcatt atcggtttac agtggcatcc agagtttctg gttaatgaag
    10621 aagatggcaa tttagaatta tttgagtatt tattgaatga actgtaacga ttggaacatc
    10681 tggtcgttct ttcttttatt ttttcaaaat ttttagaatg tggcatttta cgcaaacgtt
    10741 tgaattctga taaaaattgg agaaattcga caaaaaaact tgaaaaaaac gaaggtaagc
    10801 gttatgatag aaaagaagaa atattggagg aagaacatgt cacatattaa atttgattat
    10861 tcaaaagttt tagacaaatt tgttgcacca catgaagtgg aatacatgca atcacaagta
    10921 acagcagcag atgaattgat ccgtaaagga actggtgctg gtagcgactt cttgggatgg
    10981 ttggaccttc ctgaaaaata cgatcgcgaa gaatttgacc gcatcttgaa agctgctgag
    11041 caaatcaagt cagacagcga tgttttggtt gtgatcggta ttggtggatc ttaccttggt
    11101 gcaaaagcag caatcgactt cttgaatcac cattttgcta acttgcaaac aaaagaagaa
    11161 cgcaaagctc cacaaatcct ttacgcagga aactcaatct catctactta ccttgctgac
    11221 ttggtagagt atgttgcaga caaagacttc tcagtaaacg taatttctaa atcaggtaca
    11281 acaactgaac cagcgattgc tttccgtgtc tttaaagaac tcttggttaa gaaatacggt
    11341 caagaagaag ctaacaaacg tatctatgca acaactgacc gccaaaaggg tgctgttaag
    11401 gttgaagcag acgctaacgg ttggggaaca tttgttgttc cagatgatat cggtggacgc
    11461 ttctcagtat tgacagccgt tggtttgctt ccaatcgcag catcaggagc tgacatcaaa
    11521 gctcttatgg aaggtgcgaa tgcagctcgc aaagactaca cttcagacaa aatctctgaa
    11581 aacgaagctt accaatacgc agctgttcgt aacatccttt atcgtaaagg ctatgcaact
    11641 gagatcttgg taaactatga gccatcactt caatacttct cagaatggtg gaaacaattg
    11701 gctggtgaat cagaaggaaa agaccaaaaa ggtatctacc caacttcagc caacttctca
    11761 actgacttgc actcacttgg tcaatttatc caagaaggaa ctcgtatcat gtttgaaaca
    11821 gttgtccgtg ttgacaaacc tcgtaaaaac gtgcttattc ctactttgga agaagacctt
    11881 gacggacttg gttaccttca aggaaaagac gttgactttg taaacaaaaa agcaactgac
    11941 ggtgttcttc ttgcccacac agatggtgat gtaccaaaca tgtatgtgac tcttccagag
    12001 caagacgctt tcactcttgg ttacactatc tacttcttcg aattggcaat tgccctttca
    12061 ggttacttga atgctatcaa cccatttgac caaccaggtg ttgaagctta taaacgtaac
    12121 atgtttgccc ttcttggaaa accaggattt gaagaattga gcaaagaact taacgcacgt
    12181 ctataataga agaaaagagt ggtttgccca ctctttttac tctctttatc catagaaatt
    12241 ggactcagcc aagacttgtg atataatata gaaagcaaaa aggcagacgc ctagataata
    12301 ggagaaacta tgtcaaaaga tatccgcgta cgttacgcac caagtccaac aggactacta
    12361 cacatcggaa atgctcgtac agcattgttt aattacttgt atgcgcgcca tcatggtgga
    12421 acatttctca tccgtatcga agatactgac cgtaaacgcc atgtcgagga tggtgaacgt
    12481 tcacaacttg aaaaccttcg ctggttaggc atggattggg atgaaagtcc agaatcacat
    12541 gagaattatc gccagtctga gcgtttggac ttgtatcaaa aatacattga ccaactatta
    12601 gctgaaggaa aagcctataa atcttacgtt acagaagaag agttggcagc tgaacgcgaa
    12661 cgccaagaag tagctggcga aacaccacgc tacatcaatg aataccttgg tatgagtgaa
    12721 gaagaaaaag cagcttacat cgcagaacgt gaagcagcag ggatcatccc aactgttcgt
    12781 ttggctgtca atgagtcagg tatctacaag tggcatgata tggtcaaagg cgatatcgaa
    12841 tttgaaggtg gcaatatcgg tggtgactgg attatccaaa agaaagacgg ttacccaact
    12901 tacaactttg ccgttgccat cgatgaccac gatatgcaaa tctctcatgt tatccgtgga
    12961 gatgaccata ttgctaatac accaaaacag cttatggtct atgaagctct tggttgggaa
    13021 gctccagagt tcggtcacat gaccttgatt atcaactctg agactggtaa gaagttatct
    13081 aaacgtgata ctaatacact tcaatttatc gaagattacc gaaagaaagg ttaccttcca
    13141 gaagcagtct ttaactttat tgctcttctt ggttggaacc caggtggtga agatgagatt
    13201 ttctctcgtg aagaactcat taaacttttt gatgaaaacc gcctcagcaa gtcaccagca
    13261 gcctttgatc agaaaaaact agactggatg agcaatgatt atatcaagaa tgcagacctt
    13321 gaaaccatct ttgaaatggc aaaaccattc ttagaggaag caggccgttt gactgacaag
    13381 gctgaaaaat tagttgagct ctataaacca caaataaaat cagtagatga gattatccca
    13441 ttgacagatc ttttcttctc agatttccca gaattgacag aagcagagcg cgaagtcatg
    13501 acgggtgaaa cagttccaac agttcttgaa gcattcaaag caaaacttga agcgatgaca
    13561 gatgataaat ttgtgacaga aaatatcttc ccacaaatta aagcagtcca aaaagaaaca
    13621 ggtattaaag ggaaaaatct tttcatgcct attcgtatcg cagtttcagg cgaaatgcat
    13681 gggccagaat taccagatac aattttcttg cttggacgtg aaaaatcaat tcagcatatc
    13741 gaaaacatgc taaaagaaat ctctaaataa agaggataca ataatggaca tctgggaaaa
    13801 gatgtacgaa gaagcacaga aactatacaa tccacatgaa gtatcagact ttgtttatgc
    13861 caatcatgtt gtagctgcag tagaagcaga agatggacaa atatttacag gattctgtat
    13921 ggagggaacc tgtggtgttt tccatctctg cgcagaacgg gcggccctct tcaatatgta
    13981 ccaattttca ggacaaacta aggttaagaa agtattagcc tttcgagaca aaccacctta
    14041 tggtggaagt tcagccatgc cttgcggtgc ttgtagagaa ttccttttag agcttaatgc
    14101 tgaaaataaa gatgcagaat tcatgatgga ctataatata agaaaaacag ttaaagtcgc
    14161 agaactaatc ccttattggt ggggaaaaga acgtgcttct aagtttaatg agcgatagaa
    14221 gagtcagtat aattctggct ctttttacta taagttgcaa aaaaaataaa aaaaattaga
    14281 aaaagtagtt gacaaagttt gaaaag
//
LOCUS       DBERPV010000042        12747 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.42, whole genome shotgun sequence.
ACCESSION   DBERPV010000042 DBERPV010000000
VERSION     DBERPV010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12747
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.42"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..238)
                     /locus_tag="ACL8C7_001770"
     CDS             complement(<1..238)
                     /locus_tag="ACL8C7_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CAT RNA binding domain-containing protein"
                     /protein_id="HGS1395919.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKIGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIIN"
     gene            complement(538..3216)
                     /locus_tag="ACL8C7_001771"
     CDS             complement(538..3216)
                     /locus_tag="ACL8C7_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HGS1395920.1"
                     /translation="MAVFVSLDGIVVEVLDVFSSFNGDSEFFLCKRLKDKSQFVMERS
                     QFEEMFQLQSSRLTTQEKLQLFTSVFAGRYDVYAKSFINDQGKIQYFPSYDYGWKQLL
                     PEKRSFQTLTDSVLKSHFRGETAIGIFPMHLDDSCHFLVLDFDEGDWKEAGLTIRRIA
                     RERQMEAHLEISRSGHGLHIWFFFEEAIPSREARLFGKKLLELAMQESMQLSFDSFDR
                     MFPNQDVLPKGGFGNLIALPFQGEAYHQGRTVFVDEQFQPYEDQWRYLQEIQRVSTAK
                     VALLIQEELGKQELDKELKIVLSNMIQLEKSSVTPKTLFFLKNMASFSNPEFYLKQAM
                     RQPTYQIPERMYLFGESDHYLWLPRGLLYPLQDKFKQVSVEDRRKVQRSISVEFKGEL
                     TFEQELALSDMTSKENGLLHAETGFGKTVLGAALISERKTKTIILVHNKQLLDQWLDR
                     LNCFLTFEEEEAIRYTASGREKVIGYVGQYGGTKKWLSKLVDVVMIQSLFKLENSQSL
                     LDEYEMMIVDECHHVSALMFEKVVAQFRGKYLYGLTATPERKNGHEPIVFQRIGEILH
                     TADKRETDFKRQLQLRFTSFGHLEIEKTKASNFIQLSDWIATDSARNQLILKDILAQV
                     AEGRNILVLVNRIQQIDVFEKLLKEKEVDDCYIISGKTKVRERTSLLETLEQLDKGFV
                     LLSTGKYIGEGFDLPQLDTLILAAPFSWKNNLIQYAGRIHRNYKDKSLVRIFDYVDIH
                     VPYLEKMFQKRQVAYRKMDYRVIEGEEKQFVYVDSRYEKVLREDLAGERQECLLILPY
                     VHQTKLMNFLKEFRISQIEICIPETVANKAWLDQLKSQKIKVSFTQSKIVTPILLVNK
                     TIVWYGAMPLFGKVDEMTILRLESASIVSELVAGLR"
     gene            complement(3319..3480)
                     /locus_tag="ACL8C7_001772"
     CDS             complement(3319..3480)
                     /locus_tag="ACL8C7_001772"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395921.1"
                     /translation="MKEREVLTGQRLNELEINGIRLTKFKNGEIGIEFIWIDIENPPS
                     DAIGWVAKK"
     gene            complement(3502..4257)
                     /locus_tag="ACL8C7_001773"
     CDS             complement(3502..4257)
                     /locus_tag="ACL8C7_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HGS1395922.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSLEDLY"
     gene            complement(4328..6979)
                     /locus_tag="ACL8C7_001774"
     CDS             complement(4328..6979)
                     /locus_tag="ACL8C7_001774"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HGS1395923.1"
                     /translation="MSKELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VNLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAINPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNDLAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNVDGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSCEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVVHDNVTKVATGEAGNVTDRWILHNLNETIGKA
                     TANFDKFEFGVAGHILYNFIWDEFADWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAEYPTVNPAFEDLVAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLVDLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     EKDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(6972..7550)
                     /locus_tag="ACL8C7_001775"
     CDS             complement(6972..7550)
                     /locus_tag="ACL8C7_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGS1395924.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYQLMYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(7550..8110)
                     /locus_tag="ACL8C7_001776"
     CDS             complement(7550..8110)
                     /locus_tag="ACL8C7_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGS1395925.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSIYFNHRHEDDVMEIGY
                     TLHSDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDAQGNCCDDLRYALLKSEWEVI"
     gene            complement(8097..8675)
                     /locus_tag="ACL8C7_001777"
     CDS             complement(8097..8675)
                     /locus_tag="ACL8C7_001777"
                     /EC_number="1.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HGS1395926.1"
                     /translation="MKQSFKTNKLYYGFPVFILGYQDQNFSYNIMTCSSSYSLGDWVV
                     IGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEKLERLGVHYEISERTQ
                     IPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDEKGHFKNQLFAPTYFM
                     GDGYQRVYRYLDKCVDMKGSFIKKARKKDGKN"
     gene            complement(8958..9353)
                     /locus_tag="ACL8C7_001778"
     CDS             complement(8958..9353)
                     /locus_tag="ACL8C7_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HGS1395927.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENDIKFK"
     gene            complement(9449..9703)
                     /locus_tag="ACL8C7_001779"
     CDS             complement(9449..9703)
                     /locus_tag="ACL8C7_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HGS1395928.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            complement(9713..11047)
                     /locus_tag="ACL8C7_001780"
     CDS             complement(9713..11047)
                     /locus_tag="ACL8C7_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HGS1395929.1"
                     /translation="MTDERIHILRDILLELHNGVSPESVQDRFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVLDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYELMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(11047..11280)
                     /locus_tag="ACL8C7_001781"
     CDS             complement(11047..11280)
                     /locus_tag="ACL8C7_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HGS1395930.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            complement(11683..11865)
                     /locus_tag="ACL8C7_001782"
     CDS             complement(11683..11865)
                     /locus_tag="ACL8C7_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395931.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(11867..12646)
                     /locus_tag="ACL8C7_001783"
                     /pseudo
     CDS             complement(11867..12646)
                     /locus_tag="ACL8C7_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         3727 a         2885 c         2258 g         3877 t
ORIGIN      
        1 gattaattat tttttcggtg atgtacacca actccaaagg aacgttaata aacatctctg
       61 taaaacgggt catattatct ctatttttga gaaaaaaact tttctcaata tcaattggat
      121 ttactttatc tccaattttt cttccaaaag ctattcccct tccaaaaaga agaatatcga
      181 tatctttttt actttgcgca attacggcat tgtggtttag tattcgtttt atgatcataa
      241 aatttccctt ttaaaataaa aggaacctac ttaaaaacat caagaaactt cttctgatgt
      301 gattaaatag gttcctgctc acttgtatta gtgataacat ccttttattt caatttttaa
      361 tggtgacatg aagcttaaat aattaataac tctgtaaccg tttttatttt atgatatttc
      421 aatctatttg tcaagtactt ataaaaattt ttttattttg tgtgattcga atgtgataat
      481 ggcaacagtc tcactaaaga aatgaaaatc atacatagaa atttttaaaa attttctcta
      541 tcgtaaacct gccactagtt cagaaactat actagctgat tccaaacgta atatggtcat
      601 ctcatctacc ttcccgaata atggcattgc accataccaa acaatagtct tattcaccaa
      661 aagaataggc gttactattt ttgattgagt aaaagacact ttaattttct ggctcttcaa
      721 ctggtctagc catgctttat ttgcaaccgt ctctggtata catatctcaa tttgactaat
      781 cctaaattct tttagaaaat tcatcagttt tgtctggtgc acataaggta aaataagcag
      841 acattcctgt ctttcccctg ctaagtcctc tctcaacacc ttctcatatc tactatcaac
      901 ataaacgaat tgtttctcct caccctcgat gacacgataa tccatctttc gataagctac
      961 ttgtcgtttc tgaaacatct tttctaaata aggaacatga atatccacat aatcgaaaat
     1021 acgcaccaaa gacttatcct tgtagtttct atgaatccga cctgcatact gaattaaatt
     1081 atttttccaa gaaaagggtg ctgccaagat aagcgtgtcc aactgaggta agtcaaaacc
     1141 ttcgccaatg tattttccag tagacaacaa aacaaaccct ttatctaact gttctaacgt
     1201 ctccagtaaa ctcgttcttt ctcggacttt ggtttttccg ctaataatgt aacagtcatc
     1261 aacctctttc tctttcaata acttttcaaa gacatctatc tgttgaattc gattaactaa
     1321 aaccaagata ttccgtcctt ctgccacttg ggctagaata tccttgagaa tcaactgatt
     1381 cctcgctgag tcagtagcaa tccaatcact aagctgtata aaattacttg ctttggtctt
     1441 ttcaatctcc aaatgaccaa aagaagtgaa tcttaattgc aattgccgtt taaaatccgt
     1501 ttccctctta tcagcagtat ggagtatctc accaattctc tgaaaaacaa taggctcatg
     1561 accattctta cgctcaggcg tagccgtcaa accgtaaaga tacttccctc taaactgagc
     1621 aacaactttt tcaaacatca aggcagagac atgatgacac tcatccacaa tcatcatctc
     1681 atactcatcc aaaagacttt gactattttc caacttaaat agagattgaa tcataacgac
     1741 atcaaccagt ttactcagcc atttcttagt cccaccgtac tgtccaacat agccgattac
     1801 cttttcacga cctgatgccg tataacggat agcctcctcc tcttcgaaag tcaaaaagca
     1861 gtttaagcga tctagccatt ggtctaagag ttgcttatta tggactagaa taattgtttt
     1921 tgttttccgt tcagagataa gagcagcacc taaaacggtc ttcccaaaac cagtctccgc
     1981 atgaagtaaa ccattttctt tagaagtcat atctgacagg gctaactctt gctcaaaagt
     2041 gagttctccc ttaaattcca cgctaataga cctttgtacc tttctcctat cttccacaga
     2101 tacctgctta aatttatctt gcaatggata cagcaaacct cttggcaacc ataaataatg
     2161 atcggattct ccaaataaat acattctctc aggaatttga taggttggct gtcgcatagc
     2221 ctgctttaaa taaaattcgg gattagaaaa tgaagccata tttttcaaga aaaacagtgt
     2281 cttgggtgtc acagacgatt tttcaagttg gatcatattg gataagacga tcttcaactc
     2341 cttgtccaat tcttgcttgc ctaactcttc ttggattaac agtgccactt tagcagttga
     2401 aaccctctga atttcttgta gatacctcca ttggtcttca taaggctgaa actgttcatc
     2461 cacaaagacc gttcgccctt gatggtaagc ttctccttga aaaggcaagg caatcaaatt
     2521 tccaaatccc cccttaggaa ggacatcctg atttggaaac atgcgatcaa aagaatcaaa
     2581 ggacagttgc atactttcct gcattgccaa ttctaatagt ttctttccaa acaagcgagc
     2641 ctctcgactc ggaatagctt cctcaaagaa gaaccaaata tggagtccgt gacccgaacg
     2701 agaaatctct agatgggctt ccatctggcg ttccctggct attcttcgaa tggttaaacc
     2761 agcttctttc caatctcctt catcaaaatc cagtaccaaa aaatgacagc tatcatctaa
     2821 gtgcatagga aagataccga tagctgtctc cccacgaaaa tgagatttca aaacggaatc
     2881 cgtcaatgtc tggaaactcc gtttttcagg tagcaactgc ttccaaccat aatcatagga
     2941 aggaaaatac tgaattttcc cttgatcatt gataaaactc ttagcataaa catcataacg
     3001 gccagcaaac acagaggtaa acaattgtaa tttttcttgc gtcgtcaagc gactactttg
     3061 aagttggaac atctcctcga actgagagcg ttccataaca aactgactct tgtctttaag
     3121 acgtttacac aagaaaaact cactatcccc attaaaagaa gaaaagacat caagtacttc
     3181 taccacaatt ccatccaaag acacaaaaac agccataaga gtcacctcct tgattcctat
     3241 aggctgatta taacaagaat agctgaaatt gtacacgaaa ataaaatcgc ttacttgtta
     3301 caatagcttt gaaaactttt atttctttgc tacccagccg atggcatcgc taggtggatt
     3361 ttcaatatca atccagataa attcaatacc gatttcccca tttttaaact tggttaaacg
     3421 aataccgttg atttccagtt cattgagtcg ttgacccgtc aagacttctc gttctttcaa
     3481 ctggaaaagt taagggggga actaatacaa atcttctaag cttctatatt caatgatttc
     3541 atttttgata atattctttt taaactcaaa atgttttaaa ggattatcga ttaacactaa
     3601 ctttggaata tcatctagat ttgtgaccaa ggataaaata aaatccgatt gaaactcctt
     3661 gactttttca aattcttttg cagttaaacg cacacgcccc ttagattttc ggataccttt
     3721 tacttcggca aggtaagaat actcttggac atctacctga aagtcatatc catcaccata
     3781 aagacgggca tcggttaact gtccaccttg gaatttttct tctttatcaa aatgaaggat
     3841 aaaataattc tcagcctcca ttcccgtttc ctgtagacgt ttgaatttag ttcgaactat
     3901 tggtttttca acgatggtta tgcctgtttt cttcccttca ctggcaagta acattttaac
     3961 tatttcagca taactatgaa catcttcatt tccaaacatc atatcaatta aatctttacg
     4021 aaaacgataa acttcagctt tctgccacca accttttcga ttattgtcaa aataaggatc
     4081 aaataaatcc attctatttt ttacaactcc agttgtttca gcaattccca gagaaaccac
     4141 atagcgataa aactccgact tgctagagca ttgaaattct tttataaaaa gcttgtcaaa
     4201 cttggcaaga ccgtagccaa ttaaatttaa caattcataa tgagggtgtt tggacatcac
     4261 tttctccatc aatagatatt gatttcatta taccaaaaaa acacggctca tcaccgtgtt
     4321 tctgtgttta tttcaccaac ttcttcatct catcaatacg tgctacggtc gcatcatact
     4381 tggcttggta gtcggcttgt ttgtcttttt ctttttggac aacttctggt ttagcgttgg
     4441 cgacgaagcg ttcgttgctg agttttttgc caaccatgtc gagttctttc tgccatttgg
     4501 caagttcttt ttccagacgt gccaattctt cttcaacatt caagaggtct accagtggca
     4561 agaagatttc ggctcctgta ataacgcttg acatagccag ttcaggtgca gggatggttg
     4621 atgcgatttc caagtgttct ggatttgtaa agcgtttgat atagttgaca ttgctgttaa
     4681 agaaggcttc caagtcgcta tcgcttgtct taacaaggat tgtgattggc ttacttgggg
     4741 ctacgtttac ttccgcacgc gcattccgaa cggcacggat caagtctttg agactttcca
     4801 caccagtgtg agccacaagg tcttcaaagg ctgggttgac agttgggtat tctgctgtca
     4861 cgatagagcc ttctgagatt tgtccaaaaa tttcctctgt cacgaatggc atgattgggt
     4921 gaaggagacg aaggatcttg tccagagtgt aaaggagaac agaacgtgtg atgactttct
     4981 cttcttcatt atcgctataa aggacttcct tggtcaactc aacataccag tccgcaaatt
     5041 catcccagat gaagttgtag aggatgtgac cagcaacacc aaactcaaac ttatcaaagt
     5101 tagcagttgc ttttccaatc gtttcattga ggttgtggag aatccagcgg tccgtcacat
     5161 taccagcctc acctgttgca acttttgtga cattgtcatg caccacatcc agcgtcaaac
     5221 ctccattgtt catgaggatg tagcgagaga tgttccagat cttgttaatg aagttccatg
     5281 aagcatccat tttctcacaa gagaaacgca cgtcttgtcc tggcgcagaa ccgtttgaaa
     5341 ggaaccatcg aagggcatcg gcaccgtatt tctcgataac atccattggg tcaatcccgt
     5401 taccgagaga cttagacatc ttgcgtcctt gctcgtcacg aataagaccg tggataagga
     5461 cgttttggaa tggttgacgg cctgtgaatt ccaatgactg gaagatcata cgagacaccc
     5521 agaagaagat gatgtcgtaa cctgttacca aggttgaagt tgggaaataa cgtttaaagt
     5581 cttctgagtc gacttcaggc cagcccatgg ttgaaaatgg ccagagggca gaactgaacc
     5641 aagtatccaa gacgtcttcg tcctgagtcc atccgtcacc ttctggagct tcttcgccga
     5701 catacatttc accatcaaca ttgtaccaag cagggatttg gtgaccccac cagagctgac
     5761 gagagataac ccagtcgtgg acattttcca tccattgaag gaaggtatcg ttgaaacgag
     5821 gtgggtagaa ttcgaccttg tcctctgtgt cttggttggc aatggcgttc ttagccaatt
     5881 ggtccatctt gacgaaccat tgagtagaca agcgaggttc aaccacaaca cctgtacgct
     5941 ctgagtgacc aacactgtgg acacgttttt cgattttgac gagggcaccg atttcttcca
     6001 acttagcaac gactgcctta cgagcttcaa aacggtccat gcctgaaaat tcaaaggcca
     6061 agtcattcat ggttccgtcg tcgttcatga cgttgacttg tggcaagtta tgacgttggc
     6121 caaccaagaa gtcatttgga tcgtgggcag gtgtgatttt cacgacacca gtaccaaact
     6181 caggatctgc gtgctcatct ccaacgattg ggatgagttt attagcgatt ggaaggatga
     6241 cgtttttacc aatcaagtcc ttgtagcgtg ggtcttctgg attaatcgca accgcaacgt
     6301 ccccaaacat agtctcagga cgagttgtag caacttcaag ggcgcgtgaa ccatcttcca
     6361 gcatgtaatt catgtggtag aaggcacctt ctacatcctt gtgaatcacc tcaatatcag
     6421 aaagggctgt gcgagctgct gggtcccagt tgatgataaa ctcaccacgg tagatccagc
     6481 ctttcttgta aaggttcaca aagaccttac gaacagcttt tgacaaacct tcgtcaagag
     6541 tgaaacgctc acgagaatag tctacagaga gccccatctt gccccattgt tccttgatgg
     6601 tagtggcata ttcgtctttc cattcccaga ctttcgtcaa gaaagactca cgaccaaggt
     6661 catagcggga aatgccctca ccacgcaagc gctcctcaac cttagcctga gtggcaatcc
     6721 ctgcgtggtc catcccagga agccaaaggg tatcaaaacc ttgcatgcgt ttttgacgga
     6781 tgataatatc ttgcaaagtt gtatcccaag cgtgaccaag gtggagtttc ccagttacgt
     6841 ttggtggtgg aatcacgatt gaataaggct tagccttttg atcgcctgaa ggcttgaaaa
     6901 catcggcatc aagccatttt tggtaacgac cagcctcaac ctcggctgga ttgtatttag
     6961 gtgaaagttc tttagacatg tgtgtgtcct ttctctattt tgtttatttt attttgaatc
     7021 tgcttagcag cttcttctgc agacaaattc gtattattta ttttaaagta gtggtgcaac
     7081 tcattcggtt gatattggga atttaattga agtgtttcag cggtctctaa aatttctctt
     7141 tcagatacct caatatgtcg ttttaagggt ttgtgcttta atcgattctc cgttcgattt
     7201 cgacgtatgc actcttcaag acttgtttcc aactcaacaa aaagaatctc ttgatgataa
     7261 tcatccaaca aattctgaat ttgctttaaa tacatcagct gatactgatt tgaaaaatca
     7321 attacatctg ttaaaattac tgatcgctga tttcttgcac ttgctccaag gaatgaaaaa
     7381 gtgattccac gaacaaattc ccacatttcc tctgtatagt cctgatagat ttctagtgca
     7441 aaatcaatgg cttgatggtt ataaaatagg gtagcatccg tcagtcgaga taattcttga
     7501 ccaatggtca tttttcctga tgctggagca ccaatgatga aaagatgcat caaatcacct
     7561 cccactcact cttcagcaag gcatatctca aatcatcaca gcagttgcct tgagcatctt
     7621 tacggtctct tatgcgagct tcgagggtaa agccaagctt ttccgcgact cgttgacttt
     7681 gaaggttata tccaaagcaa gttagttcaa tcttgtgaag acccaaatct ttaaaggcta
     7741 agtcaatcaa ggcacgcgca gcttctggca cataacctcg cccccaatag tctgagtgta
     7801 aggtatagcc gatttccatc acatcatctt catggcgatg gttgaaatag atagagccaa
     7861 cgatcttatc cgttcctttg acgacaatcc cgtagcctgc tgggagattt tccttttgat
     7921 tacgctccgg aagaatgtgc tccagataat aaatctcatc ttccaaggtc ttgactggag
     7981 gaaaacctgc tggataggcg acctctggca aactagcata gtcaaagata tcctcagcat
     8041 ccgccacagt acggactcgt aaaacgagac gttctgtttc gattttatct ggcagctcag
     8101 ttcttgccat ccttcttcct cgcttttttg atgaaactgc ccttcatatc tacacactta
     8161 tccagatagc gataaacgcg ctgatatcca tctcccatga aataggttgg ggcaaacagt
     8221 tgatttttaa aatgtccctt ttcatccagg agttctgggg caacaagtcg ctcaagaatc
     8281 ttggcaaaga tgtggcaaat accgtcttcc tcaacaatcc tatctacccg acaatctaaa
     8341 acaagtggac aggcgtctaa aataggaatc tgagttcgtt cagaaatttc ataatgcact
     8401 cccaaacgtt ccaatttctc ctgatgactg ataaaaccag cctgctccat cgcaagcata
     8461 gaagtttcat cagaaatatt cacagtaaat ttttgatact gtttgatctg ctctgcggca
     8521 ttctctctcg caacgactcc aatcacaacc caatctccta gactataaga ggaactacag
     8581 gtcatgatgt tatagctaaa attctgatct tgatatccta aaataaaaac aggaaaacca
     8641 taatatagtt tattagtttt aaatgattgt tttataacaa cctcctttga ctaagacaca
     8701 aaagaaaagc cctgccatct acatgacagg gacgaatgtg tttatccgcg gtaccaccca
     8761 atttcgggcc aagcccgcat ctttagtctt taaaataaaa agacagaaat atttcatttt
     8821 ttcagtcatt agcaaccagt tttgacacat ttgtggactt ctcagcaccg ccactttctg
     8881 taaaatgtgg gattcaaaac acctctaatg gctctattgt agcaagattt tttcggaaat
     8941 gcaaggctca agaaaaatta cttgaacttg atatcatttt ctttcaattt cttgatggta
     9001 gctgggccga ttcctttcaa ggcaaggagt tctttttcag tccagttttt gaaatctgaa
     9061 gcagacttga ttccttcatc atagaaagtc ttggcacgat caagtggaag tccacccaaa
     9121 tttgctgcaa aatcttctac agaattagct actttttgag cttgctcttt ggtagcttct
     9181 actgcttgtt caactttttt agaaacagcc ttaccagctg cgcttgctga ctgttctgca
     9241 cgcttcacga ctttttttgt ctcatctaca accttagtca cagtacttga aaaggcacct
     9301 gcgcgacgga ggccatttcg taattgtttt ttacgattga gtttctttga catgataaaa
     9361 tcctttcaat aaaaaatccc tgctctgaca aggatttaac ataaacattc tatcaagatt
     9421 ttagtgaaaa atcaagaatc tttctcgttt aataatttcg ctcaccaaac aagccttctg
     9481 gcaaatcatg gaatcccttg cctgctttga agttttcaaa cttaccaagc aagaactgat
     9541 aagcatccaa gcgactctcg tagcgaatca tggcatcttt ggcacgctcg tcctggtctt
     9601 cttcgtaaac tttttgactt tccttgtgcg ccatatcgtt aatcatgatt tgggtattga
     9661 cccaagcttc aaattccttc ataaattctt gttcgtaact cattttttct ccttattcta
     9721 atccacgaaa atagtccgta tcaatctcac ggtagggctg gatatcctga acatactcca
     9781 acactccttg gaattctccg tcttcatcgt gtactgcagc ataggtgatg tggacaaact
     9841 tacctcgcga ctcagacttg aaccacattt catacttgtc tttgcttccc tcacgaagtc
     9901 ccttcatgat agccttgacc ttgtccagat acttaggcgg atgacagagt tcgacattgc
     9961 gcccgacttg ggacggcgtc cgtttgaaaa tcatctcatc agctggcgta ttgtcattgt
    10021 aatactggaa aatatcttct ttattgacaa aggtaatctc catagggaga tgattgagga
    10081 tgagattggc ctgctcgact gaaagatagc cattaccaaa agcctgttga ctatggcggt
    10141 ccagcacagc ttccttttcc ttaggggtaa aggtaatggt aaaatggcct tctggcgtat
    10201 ctatgacttg ttgaacttga ccttctgccg tatctagctg tacaggctcc tctgcaatct
    10261 tttcctcaat aaagctctgt cgttctggca cccatttctc tgacggacgg atgatggcat
    10321 agccataggc atcgctctcc tccgcaatct gaagccagtc atcctgagta aaagactcaa
    10381 ggagaatcat gaggaggatg gactcttcct tgaaaatcat actttcaaac tctgtcgcaa
    10441 aagcttcaaa agcttccttt acactgctaa ttgacacttc tggtagtgac ttggctgtcg
    10501 ttagagctgt ttgaaagagt tccctaatct gatcatccac tccccacata actttgggag
    10561 gtgaatcgtg tccatagcgc tccatgatag gaaagaagag ttcttcttta cgttggtaat
    10621 ggatgtcaaa ttgccccaca agtcccatct gacgcaccaa gcccttgcgc atctccgcaa
    10681 gcatttcctc gtcttccatc aactcatagg tatctaacaa tctacgaatg cgaatcaaag
    10741 ctgcacggag ggccaaattt tcttccttaa agacacgaac tgggtgccca gggtgttcgg
    10801 tatctaaaac ttcgacacct ttgatagcat ttttaaaaag attagcatgg acatcacaga
    10861 gttccataac atcttcaaaa gtgacgcccg aatccgagtt catcagctcg tgctccataa
    10921 gggaaatctc gatggctgac acgcccgtaa aggtcgcatc aaagcgatct tgaaccgact
    10981 caggagagac gccattgtgc aattctaaca aaatatcccg taggatatga atccgttcat
    11041 ctgtcattag tctaatccaa tcacttcgta gccattcgct tccagtgtgc gtacaatctt
    11101 gtccatagga gttcctgcta gcttagaacc ctgtttaagt gatactttac gaccaactgt
    11161 attgcgcatt aagggattgg caaggggttt aaaacccaac tccactagaa tttccaagac
    11221 ttctggatgc ttgtccacca cttctgcaac aggaattgac acatcgatga tattgtccat
    11281 gacgacctcc attgtatgtt ctaatactca atgaaaatca aagagcaaac taggaagcta
    11341 gccgcaggtt gctcaaaaca gtgttttgag gttgtggata gaactgacga agtcagtaac
    11401 atatatactg caaggtgaag ctgacgtggt ttgaagagat tttcgaagag tataaaatga
    11461 ttttactgct tatattatac catatggaga gagattaaaa aactagcagt ggggttcctg
    11521 ctagttttct gcgacttgga ttaccatcta gataagttta aagaaccaat ccaatatctt
    11581 gtaaaacagc aattgaactg caaaagaaat gatcatccaa aagaatttca caatcccaat
    11641 aatcggtttg ataaaaagaa tagcaagaag accaaaaaaa tttcattctc tctcctctgg
    11701 cttaatgagc caccgagccg tatccattag cttatctgca ataaagagtt ttcccagacc
    11761 aacaacgaca tggtcagctt tctttatcgt tttcatcact tttacacctt gcacggtcaa
    11821 aaagtaatta ccataaattt tagcaaaagc tttgatagga ttcatattac tctcctttga
    11881 tgatttcagc ctcttttcgg attgtttcaa catcttcttg atattgaact tcactatagt
    11941 taactagctt ggacaattct ttctgcaagc tttcacccat cggtttcata gttgcaaagg
    12001 ttaaaccacc tgaaatgata ctacccaaga taggaataaa tttccccatt cctttggcca
    12061 gccctccctt ggtaagattc acaccaaata ttcttaagac ttttttcaaa ataggatacc
    12121 aaagcgtctt tgttaaagct ttattaggta ctgttttcat tacctgtttg gcaattgtta
    12181 taccaccagc acgtagcaaa gcagcagttc cattcacccc ccaacatgac gcctagataa
    12241 agcaaaaggg tattttgagc atcttcactc aactcatctc gtgaagccca aagatcctca
    12301 taaccataaa tataacctaa ttcttgggcc aatttcagag agaaaccata aaattgagcc
    12361 acatcagctg gaatggtaat tgccatagca agccctccag gtaatcctgc caaaacagaa
    12421 gtcccactcg ctaataaaac attatcccta atacaggcat tagccactcg atctaagatt
    12481 tcttgagata agagagacgt tggaccttgt tccaataagg tagaatgtcc tgtggaccca
    12541 attctttgga aaacttatcc actaaaaatt tcgaacgatc aaccttaaca actggtagtt
    12601 ttaccacttg ttgtaatact tgcatagcta agtcttgttc agccatatac aaactcctta
    12661 tttctttttt acaccttatc atattatatt tcctacaaaa aaagcatttt ctaattagat
    12721 aacattaaaa aatacagaac ccctttt
//
LOCUS       DBERPV010000043        12199 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.43, whole genome shotgun sequence.
ACCESSION   DBERPV010000043 DBERPV010000000
VERSION     DBERPV010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12199
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.43"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(200..2458)
                     /locus_tag="ACL8C7_001784"
     CDS             complement(200..2458)
                     /locus_tag="ACL8C7_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGS1395932.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATPLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2687..2917)
                     /locus_tag="ACL8C7_001785"
     CDS             complement(2687..2917)
                     /locus_tag="ACL8C7_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HGS1395933.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3107..3790
                     /locus_tag="ACL8C7_001786"
     CDS             3107..3790
                     /locus_tag="ACL8C7_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS1395934.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3790..4524
                     /locus_tag="ACL8C7_001787"
     CDS             3790..4524
                     /locus_tag="ACL8C7_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS1395935.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVIENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4678..5535
                     /locus_tag="ACL8C7_001788"
     CDS             4678..5535
                     /locus_tag="ACL8C7_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HGS1395936.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5678..6550
                     /locus_tag="ACL8C7_001789"
     CDS             5678..6550
                     /locus_tag="ACL8C7_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HGS1395937.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQDRVSKDKLV"
     gene            6832..7515
                     /gene="rpiA"
                     /locus_tag="ACL8C7_001790"
     CDS             6832..7515
                     /gene="rpiA"
                     /locus_tag="ACL8C7_001790"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HGS1395938.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7529..8740
                     /locus_tag="ACL8C7_001791"
     CDS             7529..8740
                     /locus_tag="ACL8C7_001791"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019318858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HGS1395939.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGESGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8742..9284
                     /locus_tag="ACL8C7_001792"
     CDS             8742..9284
                     /locus_tag="ACL8C7_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HGS1395940.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYLFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYHKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9300..10109
                     /locus_tag="ACL8C7_001793"
     CDS             9300..10109
                     /locus_tag="ACL8C7_001793"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGS1395941.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10585..10980
                     /locus_tag="ACL8C7_001794"
     CDS             10585..10980
                     /locus_tag="ACL8C7_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase family protein"
                     /protein_id="HGS1395942.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGGYLAQIAAVEDYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWDAKNGF"
     gene            10990..11565
                     /locus_tag="ACL8C7_001795"
     CDS             10990..11565
                     /locus_tag="ACL8C7_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HGS1395943.1"
                     /translation="MESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKARFFKKQALPQSSSQPSAEPME
                     NIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDGSGKEIE"
     gene            11590..12102
                     /locus_tag="ACL8C7_001796"
     CDS             11590..12102
                     /locus_tag="ACL8C7_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-activated cytolysin C-terminal
                     domain-containing protein"
                     /protein_id="HGS1395944.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
BASE COUNT         3603 a         2233 c         2769 g         3594 t
ORIGIN      
        1 agattgaaat aagatgagaa caaatcgatt gggaaagtaa aattaatttc tataaatgtt
       61 ttagcaattg tttcgtacta tttcagattc agtctactat atatcataat ggacaaaggg
      121 caagctgtca agaaattaca gttattttag taaaaaaaga agcagaaaaa tttcattttc
      181 tactcctttt ctataggatt tatttttctt tttcagaact tttaacttca gcttttttgg
      241 cagatttaat ctgaatgttt cccttgctag tcataactgc tttgagatct ttttcgcttg
      301 gattttcaag gtagtagtca gtgattgtgt cctcaatata gtcttgaata gtccgacgaa
      361 gtgggcgtgc tcccattttt ggatcataac ctaggtcaac caacttttcc ttgaccttat
      421 cagttacatc caaacgaatg ttgttgctag agaggcgctt gttaacatct gctagcatga
      481 gctcgacaat ctgaaggagg ttatccttgc tgagagcctt aaattcgata atgccatcaa
      541 aacggttcat aaactctggg ctaaagaagt taccgagttc accgaggaca gaattggtac
      601 gtccttctct agcagcacca aatccaacgc tagcttcggt ctttcctgta cctgcatttg
      661 aggtcatgat aatgatggca tccttgaagc taacggtgcg tccttgcccg tctgtcaaac
      721 gaccatcgtc caagacttga agaaacatgt gcataacatc tgggtgagct ttttccactt
      781 catcgagaag gatgagagaa tatggattgt ggcgaacttt ttcagttaat tgaccagcct
      841 catcatagcc aacataacct ggaggggcgc cgaccaactt agccacacta tgtttttcca
      901 tgtattcact catatcaaag cgaatcatac tatcagcaga accaaaaagt tcgatagcca
      961 gttgtttgga aagttctgtc ttaccgacac cagttggccc aacgaagagg aagcttccga
     1021 ttgggcggtt aggggtacca agtccgacac gattacggcg aatagccttg gcaatcttat
     1081 cgactgcatc atcttggcca ataacatgag acttgagatc ttcggctaga tggatgagtt
     1141 gagattgttc tttctctttc aaatcaccaa cagggatatt ggttttctgc tcgataatgt
     1201 gctcaatagt tttctcgctg atgataggag tatcctggtc tgtgatcttt ttcttttgca
     1261 tttccttata cttggcaatc tggtcgcgga agtaggccgc cttctcaaaa tcttcttctc
     1321 gtgtagcttg agacttgaga ttttcagcct caatcaagcg ctgatcaatt actttaggat
     1381 ccacaaaatt caaggtcaag ttcatcttag aaccagcttc atctaggagg tcaatggcct
     1441 tgtcaggcaa gaagcgatct tggatgtagc gattggaaag agttgcagct gcttcaatcg
     1501 cagcatctgt atattgaacg tggtggtaat cttcgtattt cttttgaatc cctttgagaa
     1561 tagtgattgt ttcgtccacc gttggttcat cgactttaac aggctgcata cgacgctcga
     1621 gggcagcatc cttttcaatg atacggtatt cattgagggg agtagcaccg actagttgca
     1681 gttctccacg agcaagggct ggcttgagga tatttcctgc gtccatatta ccatcactcg
     1741 cagaaccagc accaacaatt tcatggattt catcgataaa gaggatgatg tcttcacgtt
     1801 tgcgaatttc ttccatgagt ttttgcatgc gttcttcaaa ttgtcctcga atccccgttc
     1861 cttgaactaa gctaaccaca tccagacgga tgacttgttt accttggagt ttatgtggca
     1921 catcgccatc gacaattttc tgagctagac cttcgacaac ggccgttttt ccgacaccag
     1981 gttcaccgat aaggacagga ttattcttgg ttctacgatt gagaatctcg atgacacgga
     2041 taatctcatc gtcgcgccca ataacggggt caatgtctcc acgacgggca atttcagtta
     2101 cattaatacc aaattcttcc agcaggcctt tttcttggct aggtggcgga gtttgagcag
     2161 atccacgatt ttgggaacca taaccgccgt ttccaccgta acctccacct gattgggttg
     2221 ggggaatagg aggagtattg ctagaaggtc tgaaattgtt tagatcattg aagaaatcac
     2281 caaagggatc gaagtcacga ttgttcagat ccgtcatacc tttgaagagg ctattgttag
     2341 gatctgtttt gataatctta tagcagtttt gacagaggtc aatttgtttt tgttttccat
     2401 tgagattggt gtaaagatga attgttgagt cgttaatttt acagttttga caaagcatac
     2461 atctacctca tttctttctt tagcctgact tgtttaaagg tcaaaaatag tcaaattcta
     2521 tactctcatt ataacaggat tggggtgtaa agcaagtaaa aagattgaag ctttgagaag
     2581 ttgttacaat gaaaattttt gtgaatttgg actataaaaa aatcctattt gtgagacaaa
     2641 aaggatttta cttagacatg cagggacaat cccagcttgt tttagattag tagagaagtt
     2701 cgtaaatttc cattgcgatt aagtcaatgc tatcaaacgt atacgtttcg cgatcttcta
     2761 cgtcacgaag ggtaaagatt gggccgtttt cttcgtcgtg gctgtacgca acttctgcaa
     2821 caacaactcc ttcgcgttca aaattacgtt ttaaatttcc gccatcgttt gccattgctt
     2881 caaggcggtt gatgattcta accaaatgtg attccatttt gattctcctt catttcttat
     2941 cgttactatt ttaccataaa ggaggccaac ttgactagaa aaaactaaga tttctcgcta
     3001 attctgctag tttaaagatt tttaaataaa ttggataaaa aatttaaatt ttaattcaaa
     3061 acatgttata atcatacagt attctatttt agaaagcagt gtgactatga atttttcttt
     3121 tttacctaag tatttacctt attttaacta tggggctgtt gtgacgattc ttatttctat
     3181 ctgtgttatc tttttgggaa ctattttggg tgttgtcttg gcttttgggc aacgttcaaa
     3241 gtttaaaccg cttgtttggt tggccaactt gtacgtttgg attttccgtg ggacaccgat
     3301 gatggttcaa attatgattg cctttgctct tatgcatatc aatgctccga ctattcagat
     3361 tggaatttta ggtgttgatt tttcgcgtct gattccaggg attttgatta tctctatgaa
     3421 tagtggtgct tatgtttcgg agactgttcg tgccggaatc aatgcggttc caaaaggtca
     3481 gctagaggcg gcttattcgc tagggattcg tcctaaaaat gcgatgcgtt atgtgatttt
     3541 gccacaagca gtcaaaaata tcttgccagc attggggaac gaatttatca ccattatcaa
     3601 ggacagctcc ctcttatcag ctattggggt catggagttg tggaatgggg ctacaacagt
     3661 ttctacaaca acctatctac ctttaacacc acttttattt gcagcatttt actacttgat
     3721 tatgacctct attctgacag tagccttgaa agcttttgaa aaacatatgg gacaaggaga
     3781 taagaaataa tgacagaaac cttgataaaa attgaaaatt tacataaatc ttttggaaag
     3841 aatgaagtat tgaagggcat caacctcgag attaaaagag gagaagttgt cgttatcatc
     3901 ggtccttcag ggagtgggaa atctaccttg cttcgctcta tgaatttgtt ggaggaagca
     3961 accaagggga aggttatctt tgagggagtc gatattacgg acaagaagaa tgacctgttt
     4021 gccatgcgtg agaagatggg catggttttc caacaattta acctctttcc taatatgact
     4081 gtgattgaaa atattacctt gtcacctatc aagaccaaag gtgaaagcag ggaagttgct
     4141 gagaagagag cccaagagct tttggaaaaa gttggtttgc cagataaggc agacgcttat
     4201 ccacagagtc tgtcgggtgg gcagcaacaa cggattgcca tcgcgcgtgg gttggctatg
     4261 gaaccagatg ttttgctctt tgacgaacca acttcagcct tggatcctga aatggtaggt
     4321 gaggtattgg ctgttatgca agaccttgcc aagtcaggga tgactatggt tatcgtaaca
     4381 catgagatgg gatttgcccg tgaggtggca gatcgtgtta tctttatggc agacggtgtg
     4441 gttgttgaag atgggacacc tgagcagatt tttgaacaaa cccaagaaca acggactaaa
     4501 gatttcttga gtaaggtttt ataatctatt ttaaaatttc aagacaagat tagtgaaaag
     4561 ttcaaccaga gctttttctt atagtttgaa actataggat aacctaggaa agaagtgtta
     4621 gagggcacta gcagtttttg gtataatgga agatatttga aagaaaagag aagtgatatg
     4681 acacagatta ttgatgggaa agctttagcg gccaaattgc aggggcagtt ggctgaaaag
     4741 actgcaaaat taaaggaaga aacagctcta gtgcctggtt tggtagtgat tttggttggg
     4801 gataatccag ccagccaagt ctacgttcgc aacaaggaga ggtcagctct tgcggctggt
     4861 tcccgtagcg aagtagtgcg agttccagag accattactc aagaggaatt gttagacctg
     4921 attgctaaat ataatcagga tccagcttgg catgggattt tggtccagtt gccattacca
     4981 aaacatatcg atgaagaggc ggttttatta gccattgacc cagaaaagga tgtggatggt
     5041 ttccatcccc taaacatggg acgtctttgg tctggacatc cagtcatgat tccctcgaca
     5101 cctgcaggaa ttatggaaat gtttcatgaa tatgggattg acttggaagg taaaaatgcg
     5161 gtcgtaatcg gtcgttcaaa tatcgttgga aaacctatgg ctcagcttct tttggctaaa
     5221 aatgcgacag taaccttgac ccactcacga actcataatc ttgccaaggt ggctgctaaa
     5281 gcagatattc ttgtagtcgc aatcggccgc gccaagtttg tgactgctga ctttgtcaaa
     5341 ccaggtgcgg ttgtcattga cgttgggatg aaccgagatg aaaatgggaa gctctgtgga
     5401 gatgttgatt atgaggcagt tgcaccactt gctagccata tcacgccagt ccctggaggt
     5461 gtcggtccta tgaccattac catgctgatg gagcaaactt atcaagcagc acttcggaca
     5521 ttggatagaa aataagagaa acattcgatt aatagagcgt attttctata gctatatcta
     5581 agaatggcag aaatgaatat taaattttag atataagatt acaaaaggag gtctgcgcct
     5641 cctttttgtt gtataataaa agtgagaggg aaaaaggatg aaagtgatta atcaaacctt
     5701 actagaaaaa gttattattg aacgttctcg ttcaagtcac aaaggagatt atggtcgtct
     5761 gctgctgctt ggtggtactt atccttatgg aggtgccatc atcatggctg ctttagcagc
     5821 tgtaaaaagc ggtgcaggat tggtgaccgt tggaacggac agggaaaata tcccggctct
     5881 gcacagccat ttacctgagc ctatggcctt ttctcttcaa gaccagcaat tgttaaaaga
     5941 gcaattggag aaggcagaag ttgtcttgtt ggggcctggt ttacgagacg atgcttctgg
     6001 agaaaatcta gtaaaacagg tctttgttaa tttaagccaa aatcagattt tgattgtaga
     6061 cggaggtgcc ttgaccattc ttgctaggac aagtttgtca tttccctcaa gccagcttat
     6121 cctaactcct caccaaaaag aatgggaaaa attatctgga attacgattg aaaagcaaaa
     6181 ggaagatgca acggctagtg ttctgacttc cttccctcaa ggaacaattt tggtggagaa
     6241 aggcccagct actcgtattt gggaagttgg ccaatctgat tattaccagt tacaggttgg
     6301 tggtccttat caggcgactg ggggaatggg agatactctg gctgggatga tcgcaggatt
     6361 tgtaggccaa ttccgacagg ccagtctcta cgagcgtgtg gcagtagcga cccatcttca
     6421 ttcagccata gcccaagaac tatctcaaga aaattatgtg gtcttaccga cggaaatcag
     6481 caggtatctt cccaaaataa tgaaaattat ttgtcaacaa gatagggtaa gcaaagataa
     6541 acttgtttaa aatagacaga taaatctact tccttctctt aatttatgat tcttgaaatg
     6601 cgcctgcttt aaggctaaac tagacatatc aaagttaaga gtttgttttt gtaactggaa
     6661 agagatgaac aaatcaaata cataaaagat aaactcattt ttattcgttt ggtaaaaata
     6721 aaatgcatat ttttaaagaa agattgatga aaaatgtaga tttgatgttt ttacttgaat
     6781 aaaaagcggt ttcatagtaa aataagaatt gagaatgatg gaggtaaatc ggtggaaaat
     6841 ctgaagaaaa tggcaggtat caaggctgct gagttcgtga gcgatggaat ggtcgttgga
     6901 cttggaacag gctcgactgc ctattatttt gtcgaagaaa tcggtcgtcg tatcaaggaa
     6961 gaaggattgc agattacagc tgtaacaact tctagtgtga ccactaaaca ggcagaaggc
     7021 cttaatatcc cgctcaagtc tattgaccaa gtagactttg tcgatgtgac ggttgatggc
     7081 gcggatgaag tggatagtca gtttaatgga atcaaaggcg gtggtggtgc ccttctcatg
     7141 gaaaaggtgg tcgcaacacc atcaaaagaa tacatttggg tggtggatga aagcaagctg
     7201 gtcgaaaaac taggtgcttt taaattgcca gtagaagtgg ttcagtatgg tgcagagcag
     7261 gtctttcgtc attttgaacg agctggctac aaaccaagtt tccgtgaaaa agacggccaa
     7321 cgttttgtga cggatatgca gaattttatc attgacctcg ccttggatgt cattgaaaat
     7381 ccaattgctt ttggacaaga attggaccat gtcgttggtg ttgtggagca tggtttattc
     7441 aaccaaatgg tggataaggt aatcgttgct ggacgagatg gagttcagat ttcaacttca
     7501 aaaaaaggaa aatagaaggg ggcataagat gtctaaattt aatcgtattc atttggtggt
     7561 actggattct gtaggaatcg gtgcagcacc agatgctaat aactttgtca atgcaggggt
     7621 tccagatgga gcttctgaca cactgggaca catttcaaaa acagttggtt tgaatgttcc
     7681 aaacatggct aaaataggtc ttggaaatat tcctcgtgaa actcctctta agactgtagc
     7741 agctgaaagc aatccaactg gatatgcaac aaaattagag gaagtatctc ttggtaagga
     7801 tactatgact ggacactggg aaatcatggg actcaacatt actgagcctt tcgatacttt
     7861 ctggaacgga ttcccagaag aaatcctgac aaaaatcgaa gaattctcag gacgcaaggt
     7921 tattcgtgaa gccaacaaac cttattcagg aacggctgtt atcgatgatt ttggaccacg
     7981 tcagatggaa actggagagt tgattatcta tacttcagct gaccctgttt tgcagattgc
     8041 tgcccacgaa gacattattc ctttggatga attgtaccgt atctgtgaat acgctcgttc
     8101 gattaccctt gagcgtcctg cccttcttgg tcgcatcatt gctcgccctt atgtaggtga
     8161 atcaggtaac ttcactcgta cggcaaaccg tcgtgacttg gctgtatctc cattttcccc
     8221 aactgttttg gataaattga atgaggctgg tatcgatact tatgctgtgg gtaaaatcaa
     8281 cgatatcttt aacggtgctg gtatcaacca tgacatgggt cacaacaagt caaatagtca
     8341 tggaattgat acactattga agactatggg acttgctgag tttgaaaaag gattctcatt
     8401 cacaaaccta gttgactttg atgcccttta cggccatcgt cgtaatgctc acggttaccg
     8461 tgattgcttg catgagtttg atgaacgctt acctgaaatt atcgcagcta tgagagagaa
     8521 tgaccttctc ttgattactg cggaccatgg aaatgaccca acgtatgcag gaacggatca
     8581 cactcgggaa tatattccat tgttggccta tagccctgcc tttaaaggaa atggtctcat
     8641 tccagtagga cattttgcgg atatttcagc gactgttgcc gataactttg gtgtggaaac
     8701 tgctatgatt ggggaaagtt tcttagataa attggtataa gatgacgcgc tatgctttgc
     8761 tggtgagagg tatcaatgtt ggtggtaaga ataaggtcgt catggcggag cttcgtcaag
     8821 aattgacaaa cttgggactg gaaaaggttg agagctacat caacagtggc aatattttct
     8881 ttacttcgat agattccaaa gcccaattgg ttgaaaagct agagactttc tttgcagtcc
     8941 attatctatt tattcagagc ttttctttac tgagtctaga ggactttgag gcggaacttg
     9001 aaaatctacc agcttggtgg agcagagact tggcacgaaa agattttctc ttttacactg
     9061 agggtttgga tgtggaccaa gtcatcgcga cagttgaaag tttagagctg aaagatgaag
     9121 tgctttattt tggaaaactt gggattttct gggggaaatt ttctgaagaa tcctattcta
     9181 agactgccta tcataagtac ttgctgaagg tgcctttcta ccgccacatt actattcgta
     9241 atgctaaaac ctttgacaaa attggtcaaa tgctaaaaaa ataataaagg agacacacaa
     9301 tgacattttt aaacaaaatc catgaaactg ctactttcct gaaagaaaag ggaattgcag
     9361 cccctgagtt cggtctaatc cttgggtcag gacttggaga attggcagaa gaaatcgaaa
     9421 atccagttgt agtagactat gctgagattc caaactgggg ccgttcaaca gtagtcggtc
     9481 atgctggtaa attggtatat ggtgaactgg caggtcgcaa ggtcttggct cttcaaggtc
     9541 gtttccattt ctatgaaggg aatcctctgg aagtggtgac tttcccagtt cgtgtgatga
     9601 aagttcttgg atgtgaaggt gttattgtaa ccaatgcagc tggcggtatc ggatttggtc
     9661 ctggtacctt gatggctatc tcagaccata tcaacatgac ggggcaaaat ccattgatgg
     9721 gtgaaaactt ggatgacttt ggcccacgtt tcccagatat gtctagggcc tacacaccag
     9781 aataccgtgc cactgcccat gaagtggcta aaaaacttaa tatcaagctt gatgaaggtg
     9841 tctatatcgg agttactggt ccgacttatg aaacaccagc agaaattcgt tcctataaga
     9901 cactgggagc agatgcagtt ggtatgtcta cggttcctga agttatcgtg gcagcccact
     9961 ctggcttgaa agttctggga atttcatgta tcactaactt tgcggctggt ttccaagaag
    10021 aactcaatca cgaagaagtt gtagaagtga ctgaacgtgt taaaggtgat ttcaaaggct
    10081 tgcttaaagc gattcttgct gaattgtaag aaaaaagatt taaaagggga agtgcctctg
    10141 tgttttcagg attgactgcc tatccggatt aaagaagaaa cagaggaata ctatgagctt
    10201 cttcctgctc ttataactga aagaagcgga agaataggta tgtctgatct gatagccagc
    10261 attgtgaaag acaagattct aggatactag cattagcttc ctagccaagc agactagtat
    10321 gataaggaga gatgagaatg aattgacttt ctgaatttct cagtcttatc atatatagca
    10381 caatgagatt tcgcttgagt ctgcttgtaa ataaacgaaa agaaagataa gaaataatga
    10441 aaattggtca acgaattatg cgctttggca taaaaaatta agtatcggag ttgtatctgt
    10501 tgtagtcggc tttgatttct agctccagct ggaatttcag ccaatgaagt aaagcaagat
    10561 gtaacatctg aagtggtaat aggtgtgcta gattctaagg aggaattgaa agagtcagaa
    10621 aatgatgctc caaaactaga aactcctctt agagaggagc caagactagc tcctcaaacg
    10681 cttccggaag caagtgaagt tcttgaaaac aaaagggaag agtcaaaagt agagataaca
    10741 gagccagctc aagcggatga tatccgcaag gttgttgggg aattagccaa ggatataagt
    10801 attactaagt tgtatatgac aggtcattct cttggaggct acctagctca gattgcagcg
    10861 gttgaagatt accaaaaata tcctgatttt tataaccatg tattgaggaa agtgacaact
    10921 ttcagtgctc ctaaagtgat tacttccaga actgtttggg atgctaagaa tggtttctga
    10981 gatgttggtt tggaaagtcg taaattagct gttagtggaa aaattaagca ttatgtggtt
    11041 gataatgaca atgttgtgac tcccttgatt cataataatc gtgatattgt tacatttaca
    11101 ggtaattcac gctttaaaca ccgttctcgt ggctattttg aaagtccaat gaatgatatt
    11161 cctaacttta atattggtaa acaagctacc ttggataaac atggttatcg tgatccgaaa
    11221 ttggataaag cgcgattctt taagaaacag gctctacctc aatcttctag tcaaccaagc
    11281 gctgaaccaa tggaaaatat tgccttagga aaacaggtta ctcaaagttc gacagctttc
    11341 ggaggagatg ctagaagagc tgtggatggc aaagtcgatg gtaactatgg tcacaattct
    11401 gtcactcata caaacttcca atctaagcct tggtggcaag tagatttggc taaagaagaa
    11461 accattcgcc aaatcaatat ttacaaccga acagacactg cccaggatag attggcaaac
    11521 tttgatgtca ttcttttaga cggttctggt aaagaaattg agtgaaaacg tataatatct
    11581 cctaaagatg tgtcagcaca aattacgatt aaccataaaa aagcgcgcta tgttcggatt
    11641 gagctagaag gctataatgc cctcagtctt gcagaagttg aagttttccg ctttatagct
    11701 acgaatgctg aaacggcgac acaagtttct aagccagttc aaccaatcag tcagactcct
    11761 gtgaaggata aaacattgac aattcaacac agtggagctt acattgcccg ctactccata
    11821 acttgggaag aagttccagt agataaagat ggaaaccaag ttgttcgtag tcattcttgg
    11881 gaaggaaacg gtcgcaacca gactgcaggt tttgtcctca acctcccaat caaagaaaat
    11941 atgagaaatc tgcgagttaa gattgagaaa aagacgggcc tactatggaa tagatggcaa
    12001 acaatctatg aaaacagacc aattttagct caaccccacc gtaaaattac ccattggggt
    12061 acgacattga attccaaggt gagtgacgat gatgtcttgt aatctgatgg tacaatgaca
    12121 gttagtttgt ctagtttata agaaagtact acctgagctt gaatagaact caggtagctc
    12181 tctgtgaaag aacaaaatt
//
LOCUS       DBERPV010000044        12141 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.44, whole genome shotgun sequence.
ACCESSION   DBERPV010000044 DBERPV010000000
VERSION     DBERPV010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12141
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.44"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..447
                     /locus_tag="ACL8C7_001797"
                     /pseudo
     CDS             1..447
                     /locus_tag="ACL8C7_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            597..851
                     /gene="blpM"
                     /locus_tag="ACL8C7_001798"
     CDS             597..851
                     /gene="blpM"
                     /locus_tag="ACL8C7_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HGS1395945.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            867..1070
                     /gene="blpN"
                     /locus_tag="ACL8C7_001799"
     CDS             867..1070
                     /gene="blpN"
                     /locus_tag="ACL8C7_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HGS1395946.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            1314..1463
                     /gene="blpO"
                     /locus_tag="ACL8C7_001800"
     CDS             1314..1463
                     /gene="blpO"
                     /locus_tag="ACL8C7_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HGS1395947.1"
                     /translation="MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            1567..1686
                     /locus_tag="ACL8C7_001801"
     CDS             1567..1686
                     /locus_tag="ACL8C7_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HGS1395948.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            2472..2855
                     /locus_tag="ACL8C7_001802"
     CDS             2472..2855
                     /locus_tag="ACL8C7_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HGS1395949.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            2907..3596
                     /locus_tag="ACL8C7_001803"
     CDS             2907..3596
                     /locus_tag="ACL8C7_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGS1395950.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNLF
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFLSLPSLLDIFVFATFGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            3638..3871
                     /gene="blpZ"
                     /locus_tag="ACL8C7_001804"
     CDS             3638..3871
                     /gene="blpZ"
                     /locus_tag="ACL8C7_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000276505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein BlpZ"
                     /protein_id="HGS1395951.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            4022..4633
                     /locus_tag="ACL8C7_001805"
     CDS             4022..4633
                     /locus_tag="ACL8C7_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGS1395952.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMLYNSWPLLYYL"
     gene            4794..5588
                     /gene="ccrZ"
                     /locus_tag="ACL8C7_001806"
     CDS             4794..5588
                     /gene="ccrZ"
                     /locus_tag="ACL8C7_001806"
                     /EC_number="2.7.1.15"
                     /EC_number="2.7.1.229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0051726 - regulation of cell cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell cycle regulator CcrZ"
                     /protein_id="HGS1395953.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            5585..6220
                     /gene="trmB"
                     /locus_tag="ACL8C7_001807"
     CDS             5585..6220
                     /gene="trmB"
                     /locus_tag="ACL8C7_001807"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HGS1395954.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            6347..6826
                     /gene="rimP"
                     /locus_tag="ACL8C7_001808"
     CDS             6347..6826
                     /gene="rimP"
                     /locus_tag="ACL8C7_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HGS1395955.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            6870..8006
                     /gene="nusA"
                     /locus_tag="ACL8C7_001809"
     CDS             6870..8006
                     /gene="nusA"
                     /locus_tag="ACL8C7_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HGS1395956.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            8028..8321
                     /locus_tag="ACL8C7_001810"
     CDS             8028..8321
                     /locus_tag="ACL8C7_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HGS1395957.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            8314..8613
                     /locus_tag="ACL8C7_001811"
     CDS             8314..8613
                     /locus_tag="ACL8C7_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HGS1395958.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            8630..11422
                     /gene="infB"
                     /locus_tag="ACL8C7_001812"
     CDS             8630..11422
                     /gene="infB"
                     /locus_tag="ACL8C7_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HGS1395959.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            11673..12023
                     /gene="rbfA"
                     /locus_tag="ACL8C7_001813"
     CDS             11673..12023
                     /gene="rbfA"
                     /locus_tag="ACL8C7_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HGS1395960.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
BASE COUNT         3753 a         2116 c         2747 g         3525 t
ORIGIN      
        1 gatgcgacgg aagtaaaaat caatcgccct aaaaaaacaa ttagcgaatc attctggtaa
       61 aaagaaattt cacgctatga aggctcaagc gattgtcaca agtcaaggga gaattgtttc
      121 tattgtcatg atatgaagtt gttcaaaatg agtcgcagaa atatcggaca agctggtaaa
      181 atcttggctg acagtggtta tcaagggctc atgaagatat atcctcaagc acaaacttca
      241 cgtaaatcca gcaaactcaa gccgctaaca gttgaagata aagcctgtaa ccatgcgcta
      301 tctaaggaga gaagcaaggt tgagaacatc tttgccaaag taaaaacgtt taaaatgttt
      361 tcaacaacct atcgaaatca tcgtaaacgc ttcggactac gaatgaattt gagtgttggt
      421 attatcaatc atgaactagg attctagttt tgcaggaagt ctaatgtaat ttttgcaatt
      481 caagacgttt cgatgactat tcaagatctg gatgaaaaat tttaaaaaac gatgatatac
      541 taaacttgtc aaagttacaa caagacaaaa attaaaaata aaaaagagta tttgtcatgg
      601 atacaaaaat tatggaacaa tttcatgaaa tggatataac tatgttatct agtattgaag
      661 gaggcaagaa taattggcaa actaatgtct tagaaggtgg tggtgctgct tttggtggct
      721 gggggctagg gacagctatt tgtgctgcga gtggtgttgg agcaccattt atgggagcat
      781 gtggatacat aggagctaaa tttggtgtgg atctttgggc aggagtaaca ggggcaacgg
      841 gtggatttta ataaaaggag acttgtatga atacttattg taatataaat gaaacaatgc
      901 tgagtgaggt ttatggaggt aattccggag gagcagctgt agttgctgct ttaggttgtg
      961 cagcgggtgg agtgaaatat gggagacttc taggaccatg gggcgctgca ataggaggaa
     1021 ttggaggagc agtggtttgt ggatatttag cctataccgc tacatcataa aaatgaaagc
     1081 taaattttat gaaggctata ttctttatta ttctcttcgc ttttcaaacc tatcttattt
     1141 atctatccat aagtatctcc gataaaaaac aaaagactat tgaattaaca tcattgaatt
     1201 gttttgtcat attatttcta atctatgata aattaatttt tctctttatt gcctatgttt
     1261 ttttgataat ttttatatta aacttgttcc gtaactgaaa agtgatatac tatatggata
     1321 caaaaatgat gtcacaattt gcagttatgg ataatgaaat gcttgcttgc gttgaaggtg
     1381 gagatattga ttggggaaga aaaattagtt gtgcagcagg ggttgcatat ggcgcaattg
     1441 atgggtgtgc aacaacggtt tgacatttct attgggacca tttgctatag gaataggtgt
     1501 aactggtgct gcaggtggag ctatacttgg aggtgtagcc tatgcagcaa tatgttggtg
     1561 gtaattatgg attttaaaag ttttattatt ggtttagtag ttggtatatt tggtccttat
     1621 atggatgact taattagaaa aatattttca aaatcttcca aaaaggatac ggatagtact
     1681 ctctaaaaaa taaatttctc ccctgtattt gctagcttaa tttacagggg agtttcttta
     1741 atattgtttc gcctgtcaaa atgatatgtg atagcaggat gaaaagtcta caaacaagtt
     1801 ggtatcaata caatataaag aggaaagtat gtttttaatg cttacttttt aaatttttta
     1861 acaattcaag atgtttcgat gacaattcaa gatttggatg aaaaatttta aaaaacaatg
     1921 atatactaaa cttgtcaaag ttgcaacggg tgctgctaca ttatgttaaa aatcgctctt
     1981 gattgataag ttggatttgt taggaaagga gtaaataatt atggataaga aaaagatagt
     2041 ttcgactata atatgtatag tatttcttgt agtgtcagta gataattttt ttagagactt
     2101 aaccccgtta ctgttcattt taaatattat tggcctgtct tgcttttcag tgctaacata
     2161 cattaacata aaagagatac tcttaaatat aagtaaatga tgatttggtt agtcctagaa
     2221 ccaatcaact tatgtttatc ggcttggcag attttatgtt tgtcatttgt ttgtatagag
     2281 gtatttcaga aacagaattc tatcaacaac taatcgctta tataggtgta ttctctgctt
     2341 gtttatcacg cttctgctca tgtggggctt gaagtattat aaaaagtagc tttctatcct
     2401 tttctgacag gatatttgag tagaaggctc tattaaattg ttagtgaaat aaatgaatgg
     2461 aggtatttaa tatgaaatac agattatttt ttgttatttt cttgagtagt gtgttggata
     2521 ttcttttagg gacattttta caaatctcta tcgtatctat tgggtggctt gttctttaca
     2581 gtggtttgtt tgaagcagga gttttccttc ttgctaataa aggggtggcg gtaaaaatca
     2641 aggaagtaga tattcgaaat cgctttaaat ttatttttgg aaaaacctta tggtttcaaa
     2701 ttcttttgct catctttttg ataatcaaac tttatcttgg tttggatgcg aggttgattt
     2761 tattctatgg acatattttc attgtcttta atgccttaat gtatctatta tctagtagtc
     2821 aggttagcct taaaaaaaac aaactgtctt cttaatctta cagcagtaga gcctgacaag
     2881 gtgaggtcat agtagggagg atttctatga aaaagtatca acttctattc aaaataagtg
     2941 cagtcttctc ttacttattt ttcgtatttg gtctttctca gctgacgctt atcgtccaaa
     3001 actattggca attttcttct cagataggca atttattctg gattcaaaat atcttgagtt
     3061 tactttttat tggagtcatg attgtggttc ttgttaagac aggccatggt tatctcttcc
     3121 gcattccaag aaaaaaatgg ctttggtatt cgattttgac agtattagtg gtagtgttac
     3181 agatctcttt taacgttcag acagctaaac atgttcagtc aactgcggaa ggttgggctg
     3241 tattgattgg ttatagtggg actaactttg cagagctagg tatttatata gccctgttct
     3301 ttctggttcc actgatggaa gaattgattt atagaggatt actgcaacat gctttcttta
     3361 agcattcgcg atttggcctt gatttgcttc ttccttccat tttgtttgct cttcctcatt
     3421 ttttgagtct gcctagtctg ttagatatct tcgtctttgc aacatttgga atcatctttg
     3481 ccggtttgac ccgctatacc aagagtattt atccatccta tgcggtgcat gtgatcaata
     3541 atattgtagc gaccttcccg tttttgctca cttttctaca tagggtcttg gggtaaaaaa
     3601 acaaaaggct tgcttttcag ccatagagga ggtcatcatg tataaacact tatttttcct
     3661 agattccaaa actttagatc ggttgacacc ctatattcta gtcttggctt ctgacaccat
     3721 tgcttttaat gtttttgtgc taacctttgt atctgcggtg gtttttaatt tcctaaattc
     3781 catgctagct ttaatggcta tattcatagg ggctggctat gtggtcggat tttggttact
     3841 aatactcaat gaaaatcaaa gagcaaacta ggaaactagc cgcaggctgt acttgagtac
     3901 ggcaaggcga cgttgacgtg gtttgaattt gattttcatt gagtataaaa tggtttgttt
     3961 tggaaaggct agaactaaag aatgacgtgt aggaagtctg tttgttgagg aggataattt
     4021 tatggagttt tttgataaat ttcatgcctt gtgttttgga tttttagtac taataattgt
     4081 cattacagtt ccttatacga ttaaccatgg gggttttttt caaaatgaat ctgcattgat
     4141 tcttgtaagt cttcttgtaa cctcgctgag tgttgcttat gctagaaagt ttgaaatgat
     4201 ttcttttggg atgttaagca agaaacaact tttgcttttc attgcaatct ttcttctaag
     4261 tgtacttgag acgctggttt atattcattt cttcgctgtt tcttctggct caggggtcca
     4321 acacttggcg gaagtcagca gaggaatttc cctgtctttg attttaacta cctcagtttt
     4381 tggccccatc caggaggaac tcattttcag aggacttctt caaggtgcgg tttttgacaa
     4441 ttcttggtta gggcttgtgc taacttcctc tctcttttct ttcatgcatg gaccttctaa
     4501 tgtcccttcg tttatttttt atctacttgg gggtttgttg ctgggctttg cttataaaaa
     4561 gagtcaaaac ctatgggttt ctactctagt ccatatgctt tacaacagtt ggccactctt
     4621 atattattta taaaaattat gaaaaggtaa gcagaagacg gtgcttacct ttttcaagct
     4681 ataatgatac ccaagccaat ccagaggctt ttctttgaga atcgggttag agtggttgac
     4741 gaataggcca aaaactagta gaatagtaag gaaactttat acggaggaaa gaaatggatt
     4801 tgggtgataa tgagctaaca ctgactccca tacctgggaa aagtggcaag gcttatatgg
     4861 gtagctatcc tgatgggaag cgcatctttg taaaaatgaa cacctctcca atcctacctg
     4921 gtctagctag agaacaaatt gctccacaat tattatggag tcgtcgtttg gcagatgggc
     4981 gtgatatgtg tgctcaagaa tggttgacag gcaagatatt gaccccctat gatatgaatc
     5041 gtaagcaaat cgtcaatatt ttaacccgtc ttcatcgctc acgtccgttg atgacacaat
     5101 tgagtcgttt gggctatgcc atggaaacac ctgtagattt actacagtct tggcaggaaa
     5161 cggctccaga tgctttgcgt aaaaatcatt ttatcagtga agtgatggct gatttacgtc
     5221 agactattcc aggatttaga gaggaccatg cgaccattgt ccatggagat gtacgacata
     5281 gtaattggat tgagacagat agtggcttga tttatttagt agattgggat tcggttcgct
     5341 tgaccgatcg catgtttgat gtggcccata tgctctgcca ttatatttca gaacatcagt
     5401 ggaaggaatg gttgacctac tacggttaca agtacaatca aacggtatta agtaaattgt
     5461 attggtatgg tcaattgtct tatttgagtc agatttccaa gtattatatg aaccaagatt
     5521 tagaaaatgt caatcgggag attcatggtt tgcgtcattt ccgagacaag tatggaaaga
     5581 gaagatgaga gttagaaatc gtaaaggggc aacagaatta ctagaggcaa atccccagta
     5641 tgtggtcctc aatcccttgg aagccaaggc aaaatggcgg gacttgtttg gcaatgataa
     5701 tcccattcat gtggaagttg gaagtggaaa gggtgccttt gtttcaggta tggccaagca
     5761 aaaccctgac atcaactata tcgggattga tattcaaaag tctgttttga gctacgcttt
     5821 ggacaaggtg cttgaagttg gagtgcctaa catcaagctc ttgtgggtag atggttctga
     5881 cttgactgac tactttgaag acggtgagat tgatcgcttg tatctgaact tttcagatcc
     5941 atggccgaaa aaacgccatg aaaagcgtcg tttgacctac aagacctttt tggatacctt
     6001 caaacgtatc ttgcctgaaa atggagaaat tcatttcaag acggataacc gtggcttgtt
     6061 tgagtacagt ttagtgagct tttctcaata tggcatgaaa ctcaatggtg tctggctaga
     6121 tttgcatgcc agtgattttg aaggcaatgt catgacagaa tacgagcaaa aattctcaaa
     6181 caaggggcaa gttatctacc gagttgaggc agaattttaa gagatagcct aaaattaggc
     6241 tgtacaagtg cttttgcttt acataagttg gcaaacgtgc tatactaagg gtaagaatat
     6301 gagaaagaga ggcggggaaa tatcttcgcc tcttgcttat gaggaggtgg acgcaatcgc
     6361 aacaatcgta gaattagtca gagaagttgt agaacctgtc atagaagctc cttttgaact
     6421 cgtggatatc gagtatggaa agattggcag tgacatgatt ctcagtattt ttgtagataa
     6481 acccgaagga attaccttga acgacacggc agacttgaca gaaatgatca gtcctgtcct
     6541 agacaccatc aagccagatc ccttcccaga acaatatttc ctagaaatta ccagtccagg
     6601 tttggaacgt cctttgaaaa ccaaggatgc cgtcgctgga gcggttggaa aatacatcca
     6661 tgtcgggctc taccaagcca tcgataagca aaaggtcttt gaaggaacct tgttggcctt
     6721 cgaagaggac gagttgacta tggaatatat ggacaagacg cgtaagaaaa ccgtccaaat
     6781 tccatacagt ttagtatcaa aagcacgttt agcagttaaa ttatagaaaa agaaaggata
     6841 gcttttgagg attcaaaagt gaagaaaaca tgagtaaaga aatgctagag gccttccgca
     6901 ttttggaaga agacaaggga atcaaaaaag aagatatcat cgacgcagta gtagagtcgc
     6961 ttcgttccgc ttatcgcaga cgctatggtc agtcagacag cgtagctatt gacttcaacg
     7021 aaaaaacagg tgactttaca gtttatactg tccgtgaagt tgttgatgaa gtatttgata
     7081 gccgtttgga aatcagcttg aaagatgctc ttgccattaa ttcagcttat gaacttggag
     7141 acaaaatcaa gtttgaagaa gcaccagctg agtttggtcg tgtagcagcc caatctgcca
     7201 aacaaaccat catggaaaaa atgcgcaagc aaacacgtgc catcacttac aatacttaca
     7261 aagaacatga gcaagaaatc atgtctggta cagtagaacg ctttgacaac cgctttatct
     7321 atgtcaacct tggtagcatc gaagcccaat tgtcaaaaca agaccaaatt cctggagaag
     7381 tttttgcttc tcatgatcgt atcgaagttt atgtttacaa ggttgaagac aaccctcgtg
     7441 gtgtgaacgt ctttgttagc cgtagccatc cagaaatgat caaacgtttg atggagcaag
     7501 aaattccaga agtttatgat ggaactgttg aaatcatgag cgtggctcgt gaagcaggtg
     7561 accgtacgaa ggttgctgtt cgtagccaca atccaaacgt ggatgctatc ggtacaatcg
     7621 ttggacgtgg tggtgctaat atcaagaaga ttactagcaa attccaccca gctcgttacg
     7681 atgctaaaaa tgaccgcatg gtaccaatcg aagaaaatat cgatgttatc gagtgggtag
     7741 cagatccagc tgaatttatc tacaatgcca tcgctcctgc tgaggttgac caagttatct
     7801 ttgatgaaaa cgacagcaaa cgtgccttgg tggttgttcc agataacaag ctttctcttg
     7861 ccattggtcg tcgtggacaa aacgtgcgct tggcggctca cttgactggt taccgtatcg
     7921 atatcaagtc tgctagcgaa tttgaagcca tggaagacgc tgcttcagta gagttggaag
     7981 tagaaaacga tactgtagaa gaataaaagc tgctagagga gggaaagatg aaaacaagaa
     8041 aaatcccttt gcgcaagtct gttgtgtcta acgaagtgat tgataagcgt gatttgctcc
     8101 gcattgtcaa gaacaaggaa ggacaagtct ttattgatcc tacgggcaag gccaatggcc
     8161 gcggcgctta tatcaaacta gacaatgcag aagccctaga ggcgaaaaag aagaaggtct
     8221 ttaaccgcag ctttagcatg gaagtggaag aaagctttta tgacgagttg atcgcttatg
     8281 tggatcacaa agtgaaaaga agagagttgg gacttgaata agcaaaagat aagtaatctc
     8341 ttggggcttg ctcagcgagc agggcgcatc atatcgggtg aagaattggt ggtcaaggcc
     8401 attcaagacg gcaaggccaa gttggtcttt ctagctcatg atgctggacc caatctgacc
     8461 aagaagattc aagataaaag tcattattat caagtagaaa ttgtaaccgt gttttcaaca
     8521 ctggaattaa gcatagcagt cgggaaatcg agaaaggttt tggctgtaac agatgctgga
     8581 tttacaaaga aaatgaggtc tcttatggaa tagaagagga ggacatgatt tgtctaagaa
     8641 aagattgtac gaaatcgcaa aagaacttgg aaaagaaagt aaagaagttg tagcgcgtgc
     8701 aaaagagtta ggcttggatg tgaaaagcca ctcatcaagt gtggaagaag ctgtcgctgc
     8761 aaaaattgct gccagcttta agcctgcagc tgctccgaaa gtagaagcaa aacctgcagc
     8821 accaaaagta agtgcagaaa agaaagccga aaaatctgag ccagctaaac cagctgtagc
     8881 taaggaagag gcaaaaccgg ctgagccagt tgctccgaaa acagaaaaag tagcagcgaa
     8941 accgcaaagt cgtaatttca aggctgagcg tgaagcccgt gctaaagagc aggcagaacg
     9001 acgcaagcaa aataagggca ataaccgtga ccaacaacaa aacggaaacc gtcagaaaaa
     9061 cgacggccgt aatggtggaa aacaaggtca aagcaaccgc gacaatcgtc gctttaatga
     9121 ccaagctaag aagcagcaag gtcagcaaaa acgtagaaat gagcgccgtc agcaagagga
     9181 taaacgttca aatcaagcgg ctccacgtat tgactttaaa gcccgtgcag cagccctaaa
     9241 agcagagcaa aatgcagagt acgctcgttc aagtgaggaa cgcttcaagc agtatcaggc
     9301 tgctaaagaa gccttggctc aagctaacaa acgcaaggaa ccagaggaaa tctttgaaga
     9361 agcggctaag ttagctgaac aagcacagca agttcaagca gtggttgaag tcgtccctga
     9421 gaaaaaagaa cctgcagtgg atacacgtcg taaaaaacaa gctcgaccag acaaaaatcg
     9481 tgacgattat gatcatgaag aagatggtcc tagaaaacaa caaaagaatc gaagtagtca
     9541 aaatcaagtg agaaatcaaa agaatagtaa ctggaataac aacaaaaaga acaaaaaagg
     9601 caataacaag aacaaccgta atcagactcc aaaacctgtt acggagcgta aattccatga
     9661 attgccaaca gaatttgaat atacagatgg tatgaccgtt gcggaaatcg caaaacgtat
     9721 caaacgtgaa ccagctgaaa ttgttaagaa acttttcatg atgggtgtca tggccacaca
     9781 aaaccaatcc ttggatgggg aaacaattga actcctcatg gtggattacg gtatcgaagc
     9841 aaaacaaaag gttgaagtgg ataatgctga catcgaacgt ttctttgtcg aagatggtta
     9901 tctcaatgaa gatgaattgg ttgagcgtcc accagttgtt actatcatgg gacacgttga
     9961 ccacggtaaa acaacccttt tggatactct tcgtaactca cgtgttgcga caggtgaagc
    10021 aggtggtatt actcagcata tcggtgccta ccaaatcgtg gaaaatggta agaagattac
    10081 cttccttgat acaccaggac acgcggcctt tacatcaatg cgtgcgcgtg gtgcttctgt
    10141 taccgatatt acgatcttgg tcgtagcggc agatgacggg gttatgcctc agactattga
    10201 agccatcaac cactcaaaag cagctaacgt tccaatcatc gtagctatta acaagattga
    10261 taaaccaggt gctaacccag aacgcgttat cggtgaattg gcagagcatg gtgtgatgtc
    10321 aaccgcttgg ggtggagatt ctgaatttgt tgaaatctcg gctaaattca accaaaatat
    10381 cgaagaattg ttggaaacag tccttcttgt ggctgaaatc caagaactca aagcagaccc
    10441 aacagttcgt gcgatcggta cggttatcga agcgcgcttg gataaaggaa aaggtgcggt
    10501 cgcaaccctt cttgtacaac aaggtacctt gaatgttcaa gacccaatcg ttgtcggaaa
    10561 taccttcggt cgtgtccgtg ctatgaccaa cgaccttggt cgtcgtgtta aagttgctgg
    10621 accatcaaca ccagtctcta tcacaggttt gaacgaagca ccgatggcgg gtgaccactt
    10681 tgccgtttac gaggatgaaa aatctgcgcg tgcagcaggt gaagagcgtg ccaaacgtgc
    10741 cctcatgaaa caacgtcaag ctacccaacg tgttagcctt gaaaacctct ttgataccct
    10801 taaagctggg gaactcaaat ctgttaatgt tatcatcaag gccgatgtac aaggttctgt
    10861 tgaagccctt tctgcctcac ttcaaaagat tgacgtggaa ggtgtcaaag tgactatcgt
    10921 ccactcagcg gtcggtgcta tcaacgaatc agatgtgacc cttgccgaag cttcaaatgc
    10981 ctttatcgtt ggtttcaacg tacgccctac accacaagct cgtcaacaag cagaagctga
    11041 cgatgtggaa atccgtcttc acagcattat ctacaaggtt atcgaagaga tggaagaagc
    11101 tatgaaaggg atgcttgatc cagaatttga agaaaaagtt attggtgaag cggttatccg
    11161 tgaaaccttc aaggtgtcta aagtcggaac tatcggtgga tttatggtta tcaacggtaa
    11221 ggttgcccgt gactctaaag tccgtgttat ccgtgatggt gtcgttatct atgatggcga
    11281 actcgcaagc ttgaaacact acaaagacga cgtgaaagaa gtgacaaacg gtcgtgaagg
    11341 tggattgatg atcgacggct acaatgatat taagatggat gatgtgattg aggcgtatgt
    11401 catggaagaa atcaagagat aagatttttt gctcctttct taggtggtga gggacgcaag
    11461 caaaccgatg gtttcattgc ttatttttga gcctagggtc tcaaaaatcc cctgtgatgg
    11521 gactgataaa tcagttccat cactttcacc acggcgaaag aagcagatga cttcaaattg
    11581 aacttcgttt caatttaaac tgaaaatcaa gaagtttaaa atagctaggt ctgctggcct
    11641 agcttttggt tcaaagtaga gaaaggaata tcatggcaaa tcatttccgt acagatcgtg
    11701 tgggcatgga aatcaagcgt gaagtcaatg agattttgca aaagaaagtc cgtgatccac
    11761 gtgtccaagg tgtgaccatc acagatgttc agatgctggg tgacttgtct gttgccaagg
    11821 tttattacac cattttgagt aaccttgctt cggataacca aaaagcccaa atcgggcttg
    11881 aaaaagcaac tggtaccatc aaacgtgaac ttggtcgcaa tttgaaattg tacaaaatcc
    11941 cagatttgac cttcgtcaaa gacgagtcca tcgagtatgg aaacaagatt gacgagatgc
    12001 tacgcaatct ggataagaac taaagaagag gggttgcccc tcttttttgg tggaggaaaa
    12061 taggttgaat ttgaaatgga aaaatattct tttaaaatat attgaaacta gaatagtacg
    12121 cctctacttc taaaacattg t
//
LOCUS       DBERPV010000045        11839 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.45, whole genome shotgun sequence.
ACCESSION   DBERPV010000045 DBERPV010000000
VERSION     DBERPV010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11839
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.45"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(1001..1204)
                     /locus_tag="ACL8C7_001814"
     CDS             complement(1001..1204)
                     /locus_tag="ACL8C7_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pncT"
                     /protein_id="HGS1395961.1"
                     /translation="MEKIDYITLNEVELETISGGDDCFIGDIGCIGWGLLKSIGGMIK
                     PAPYVPPVCIPKSSWNPAPPVPC"
     gene            complement(1522..1725)
                     /locus_tag="ACL8C7_001815"
     CDS             complement(1522..1725)
                     /locus_tag="ACL8C7_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin class II family protein"
                     /protein_id="HGS1395962.1"
                     /translation="MNTKMMSQFSVMDNEMLDRIEGGIFGVDDALFWAGLGYVAGSIV
                     DTAIDDFTNQCRKNPHQWFCVRV"
     gene            2006..4159
                     /gene="blpA"
                     /locus_tag="ACL8C7_001816"
     CDS             2006..4159
                     /gene="blpA"
                     /locus_tag="ACL8C7_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter BlpA"
                     /protein_id="HGS1395963.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLVIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
                     IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYIL
                     QQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDANSII
                     DALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFEKMNH
                     DVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQT
                     SLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQS
                     AKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDINLTIK
                     QGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINYLPQQ
                     AYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGG
                     QKQRIALARALLTKSPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAE
                     RTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            4170..5531
                     /locus_tag="ACL8C7_001817"
     CDS             4170..5531
                     /locus_tag="ACL8C7_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HGS1395964.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLSNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTSPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            5588..5716
                     /gene="blpC"
                     /locus_tag="ACL8C7_001818"
     CDS             5588..5716
                     /gene="blpC"
                     /locus_tag="ACL8C7_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HGS1395965.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDLLYNINRYAHYIT"
     gene            complement(5787..7127)
                     /locus_tag="ACL8C7_001819"
     CDS             complement(5787..7127)
                     /locus_tag="ACL8C7_001819"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGS1395966.1"
                     /translation="MNIAWILLYTLVTNGLEIVIFFKVDGIDLAFERIFKAFLFKILL
                     AFVFVMISYIVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRKEILDKAFQK
                     SLTQINWIMGGYYLVMESLSFFEYEQSIQSKTVRHLILVFYLLFFMGVIKKLDTYLKE
                     KLYERLEQEQALRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYGSVLKDSSQKLQNNKYDLGRLVNIRDKALKSLLAGKFLKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTIVSILCDNAIEASVEASQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQNQVFRQVLTVIHTE"
     gene            complement(7141..7878)
                     /locus_tag="ACL8C7_001820"
     CDS             complement(7141..7878)
                     /locus_tag="ACL8C7_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS1395967.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINKLH"
     gene            complement(7883..8221)
                     /locus_tag="ACL8C7_001821"
     CDS             complement(7883..8221)
                     /locus_tag="ACL8C7_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGS1395968.1"
                     /translation="MKYMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            8497..8826
                     /locus_tag="ACL8C7_001822"
     CDS             8497..8826
                     /locus_tag="ACL8C7_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HGS1395969.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKTETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(8994..10043)
                     /locus_tag="ACL8C7_001823"
     CDS             complement(8994..10043)
                     /locus_tag="ACL8C7_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1395970.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFCQKASKFFTETG
                     LDWDYLISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(10040..10771)
                     /locus_tag="ACL8C7_001824"
     CDS             complement(10040..10771)
                     /locus_tag="ACL8C7_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1395971.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLDQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            10839..11249
                     /locus_tag="ACL8C7_001825"
     CDS             10839..11249
                     /locus_tag="ACL8C7_001825"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGS1395972.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            11259..11546
                     /locus_tag="ACL8C7_001826"
     CDS             11259..11546
                     /locus_tag="ACL8C7_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395973.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            11630..>11839
                     /locus_tag="ACL8C7_001827"
     CDS             11630..>11839
                     /locus_tag="ACL8C7_001827"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1395974.1"
                     /translation="MLEITLKSSYQFVHILFQSIIYIPSTMHHNLGNSYSIKIKKQTR
                     KLGTDCSKHRFKVVDRTDEVSSKHRF"
BASE COUNT         3963 a         2455 c         1978 g         3443 t
ORIGIN      
        1 aactatagta aaatgaaata agaacaggat aaatcgatca ggacagtcaa atcgatttct
       61 aacaatgttt tagaagtaga gacgtactat tctagtttca atctactata ctataccata
      121 ttttgtttcg cagggaatct attataaaag ggtaagtatt tcaaaaacac ttaccccttt
      181 atactttatt aagctctact ttttataata cttcaatccc caaatgaaag gaagatgttc
      241 cgttttttag caagaaaagt tttcatttct ttgctccttt ctttttagtt aaagcaaaat
      301 agatcataac tgcaatcaca taggctatgg tataaaatag ctgataccaa atactttccc
      361 taagcggata aagaaagatg gacatgatta gatacaagat gaaaatgata agtatttttt
      421 tcttcataaa atttcctcct aaatgtgtga tttatcttag ttgaacaaga atctttacac
      481 tgctagtata gcactcattt tgaccttgga ttactcaaat catgaatggt catcaaaaca
      541 tcttgaacaa taacaagatt ttcatctata caaaaatagt tatactcaac aacaatcaaa
      601 ctaaagaacc aaataaatat agcttaacat actttttttg gatttcaaac aatactgata
      661 aaattaataa taaatctgtg gtagtacttc ccatccctac tgctttccaa ttttataata
      721 ttattaatta aataatatat gagaaaaaac gaacaagact gtgttaataa tctatcttat
      781 tcgttttatt tattagactt gttcagaaat tatttgaagc agtattagct ggttagaaag
      841 tgaattttta acgttccaac cagccattag tttctagttt tcgactcttg caataagcta
      901 aaataatcct gaacaacacc tgtatattat aattgcgaag attcaacaaa atagcgaaca
      961 agtcgattat tcatttttta tataagttta caataacttt ttaacatgga actggaggtg
     1021 caggattcca cgaacttttt ggaatgcata ctggaggaac atatggagca ggttttatca
     1081 tccctccgat actcttcaaa agcccccagc cgatacatcc gatatctcca ataaaacagt
     1141 catctccacc actaatcgtc tctaattcta cttcattcaa agtaatataa tcaatttttt
     1201 ccattgttat aattcattcc tttcgtttta ctcaaggcac aacacagaat gaaaaagtgt
     1261 tgtactcttt attttataat gtttataata atagtgagaa aacctatcac tactacaaat
     1321 cacggggagg tgaataagtg agtgatatag ccaatatctc gcatttttat aggtgtcatt
     1381 ctttctatca agcacaagaa ctgtgactag gagcacgtaa acttataaca gaataagcga
     1441 ctcgtttgca aaagaatagt ttctatcact gcataggtca ttaagttata taaattctta
     1501 tacaatacaa cactactata tctatacacg aacacagaac cactgatgag gatttttccg
     1561 gcattgattc gtaaaatcat caattgctgt atcaacaatg ctacctgcaa catagcctaa
     1621 ccctgcccaa aacaaagcat cgtcaactcc aaatattcct ccctctatcc tatcaagcat
     1681 ttcattatcc ataacagaaa attgtgacat catttttgta ttcatgacaa atactccttt
     1741 tttattttta atttttgtct tgttgcaact ttgacaagtt tagtatatca ttatttttta
     1801 atttttttca tccaaatctt gaattgccat cgaaacgtct tgaattagct tttttatttc
     1861 aagccacctc taaatgttta aaaaaaataa tttctaatca cttttttacc attcaggaag
     1921 ttttaatgac tattcaagat ttcataaaat atgaacttag ttttatggca taatatacct
     1981 atccactata tgaaaggaat tgccaatgac ttcttataaa cgtacatttg ttcctcaaat
     2041 agatgcgaga gactgtggtg tcgctgcctt agcctcgatt gctaaattct atggttcaga
     2101 tttttctcta gctcacttga gagaacttgc aaagaccaat aaagaaggga cgactgctct
     2161 tggcattgta aaagccgctg atgaaatggg ctttgaaaca aggcctgttc aagcagataa
     2221 aactctcttt gacatgagtg atgtccccta tccatttatc gttcacgtta acaaagaagg
     2281 aaaactccaa cattactatg ttgtctatca aacaaagaaa gactatctgg ttattggtga
     2341 tcctgaccct tctgtaaaaa tcactaaaat gtcaaaagaa cgctttttct ctgaatggac
     2401 tggagtagct atttttctag ctcccaaacc cagctatcaa ccccataaag ataaaaagaa
     2461 tggtctacta agcttccttc ctctgatttt caaacaaaaa tctctcattg cttacattgt
     2521 tctctcaagc ttattggtca ctattatcaa tataggtggt tcttattatc tccaaggaat
     2581 cttagatgaa tacatcccaa atcagatgaa atcaacttta ggaatcatct cagttggtct
     2641 ggttatcacc tatatcctcc aacaagtcat gagcttctcc agagattatc tcctaaccgt
     2701 tctgagccag agattaagca ttgatgtgat tttatcctat attcgccata tttttgaact
     2761 tcccatgtct ttctttgcga cacgtcgtac aggagaaatc atttcacggt tcacagatgc
     2821 taactctatt atagatgcct tggcttctac cattctttct cttttcctgg atgtttctat
     2881 tctgattctt gtagggggcg tcttactggc acaaaaccct aatctcttcc ttctttctct
     2941 tatttctatt cctatataca tgttcatcat cttttctttt atgaagcctt tcgaaaaaat
     3001 gaaccatgat gtcatgcaaa gtaattctat ggttagctct gccattatcg aagatatcaa
     3061 cgggattgaa actataaagt cgctcacgag tgaagaaaat cgctatcaaa atatagacag
     3121 cgaatttgta gattatttgg aaaaatcctt taagctcagt aaatattcta ttttacaaac
     3181 aagtttaaag cagggaacaa aattagttct gaatatcctt atcctatggt ttggcgctca
     3241 attagtcatg tcgagtaaaa tttctatcgg tcagctgatt acctttaaca cacttttttc
     3301 ttactttaca actcctatgg aaaatattat caacctccaa accaaactcc aatctgcgaa
     3361 ggttgctaat aaccgtttga acgaagtcta tctagtcgaa tctgaatttc aagttcaaga
     3421 aaaccctgtt cattcacatt ttttgatggg cgatattgaa tttgatgacc tttcttataa
     3481 gtatggtttt ggacgagata ccttaacaga tattaatctc acgattaaac aaggagataa
     3541 ggttagccta gttggagtta gtggttctgg taaaacaact ttagccaaaa tgattgtcaa
     3601 tttctttgaa ccctacaaag gacatatttc catcaatcat caggatatta aaaacattga
     3661 taaaaaagtc ttgcgccgtc atattaatta cctaccacaa caagcctata tctttaatgg
     3721 ctctatcttg gaaaacttaa ctttgggcgg taatcatatg attagccaag aagatattct
     3781 aagagcttgt gaattagctg aaattcgtca agacattgaa agaatgccta tgggctatca
     3841 aactcagctc tctgatggag ctggtctatc aggaggacaa aagcaacgaa tagccctcgc
     3901 tcgtgctctt ttaactaaat ctcctgtttt aatactagac gaagctacta gcggtcttga
     3961 tgtcttgact gagaaaaagg ttatagataa tcttatgtct ctaactgata aaaccattct
     4021 ctttgtagcc catcgtctca gtatagccga acgaaccaac cgtgtcattg ttcttgacca
     4081 ggggaaaatc attgaagttg gtagtcacca agagttaatg caggcgcaag gtttctacca
     4141 tcatctattc aataaataag gagaatgtca tgaatcctaa tctttttaga agcgtcgagt
     4201 tttatcagag acgttaccat aactatgcga cagtgttaat tatacctctt tcattactat
     4261 ttactttcat cttgattttc tcccttgttg ccacaaaaga aattactgtt acttcccaag
     4321 gagaaatcgc ccctacaagt gtcattgcct ccattcagtc aaccagtgat aatcctatcc
     4381 tagctaatca tttagtggca aatcaagtag ttgaaaaagg ggacttactc atcaaatact
     4441 ctgaaacaat ggaagaaagt cagaaaactg ccttagcaac tcaattacaa agacttgaga
     4501 agcaaaaaga aggacttgga attttgaaac aaagcttaga aaaagcgact gatctttttt
     4561 ctggcgagga tgaatttggc taccataata cctttatgaa ttttactaaa caatcccatg
     4621 atattgaact gggtatcaca aagactaaca ccgaagtttc aaatcaagct aatctttcca
     4681 atagcagttc atcagctatt gaacaagaaa ttacaaaagt tcaacaacaa attggagaat
     4741 atcaagagtt gagagatgct atcataaata acagagcacg cttaccaact ggcaatccgc
     4801 accagtcaat tttgaatcgt tatcttgtag cctcacaagg acaaacacaa ggaactgcag
     4861 aggagccatt tttatctcaa attaatcaaa gtattgcagg tcttgaatca tctatcgcaa
     4921 gcctcaaaat tcagcaagct ggtatcggaa gtgtagcaac ttatgataac agtttagcaa
     4981 ccaaaattga agtactccgc actcagtttt tacagacagc ctcacagcaa caactaactg
     5041 tggagaatca attaacagaa ttaaaagtac aactagatca agccacacag cgtttggaaa
     5101 acaatacctt aacctcccca agtaaaggta tcgttcatct gaacagcgaa tttgaaggta
     5161 aaaatagaat tccaactggt acagaaattg ctcaaatatt ccctgtcatc acagatacaa
     5221 gagaagtact aatcacttac tacgtatctt ctgactatct acctctacta gataaaggac
     5281 aaactgtaag attaaaactg gagaagattg gaaatcacgg caccaccatc atcggccaac
     5341 ttcagacaat tgatcaaact cctaccagaa cagagcaagg aaatctcttt aaattaaccg
     5401 ctcttgcaaa actatctaac gaggatagta aactcatcca atatggctta caaggtcgcg
     5461 tcactagtgt aactacaaag aaaacatatt ttgattattt caaagataaa attttaacac
     5521 attctgatta attttcagat aacactctat aactatttat tatcttatca aaaaggagaa
     5581 tcataacatg gataagaaac aaaacctaac ttcatttcaa gaactaacaa ctaccgaact
     5641 caaccaaatt acaggtggag gattgtggga agatttatta tataacatta atagatatgc
     5701 tcattacatc acataagaac ttcatcatcc aatacaacta taaaaaaata agaccgagaa
     5761 acaagtactc tcggtcttat ttttcatcat tctgtatgta tcacagtaag tacctgacga
     5821 aagacttgat tttgacaggt ggtatttaga ctggtattag gatggctttc cacaatcttc
     5881 atgacggtat agagaccaac tcctctctcc tcccctttag aactggctcc aaaggagaag
     5941 atttcagaaa tatcgatgcc ctcttctttg atggagtttt cgatgataaa ggtctcctgt
     6001 gctccatttt ttaaaaaggc gattgaaaca tgaggttgac tagcttccac actggcttca
     6061 atagcattgt cacaaaggat agacacaatg gttagaaaat caagtagact catcccctcg
     6121 acctgaatct cctcaggaac ttcgacatta aagacaatgt tcttatctct ggcttttaaa
     6181 aatttccctg ctagaagact tttgagggct ttatcacgaa tatttaccaa tctgcccagg
     6241 tcatatttat tgttctgcaa tttctgactg gaatccttta agacggagcc atagacctct
     6301 tttatctgct ccatatcctc ctcttcaatg cccagacgta agctagtcaa gaggttggta
     6361 taatcatggc gaaaactccg tacttccttg taaagctcct ctatatgccg actatagcgt
     6421 tccatatctc tatagcgcag ggcctgctct tgttccaatc tctcatagag tttttccttc
     6481 aaataggtat ccaatttctt gataaccccc ataaaaaaga gtaggtaaaa gactaggatg
     6541 agatggcgaa cagtctttga ttgaatactt tgttcatatt caaaaaaaga cagactttcc
     6601 atgactagat agtagccacc cattatccag ttaatctgag tcagggactt ttgaaaggct
     6661 ttatcgagaa tctcctttct caagctagta aaatcgtagt ccaaccattt caaaaaagct
     6721 agagaaatga agaaattgaa aattattata cataacccag taaatgagta gccatcatat
     6781 acttgccctt gtcccaaaaa tggaagcaca aaataggaga ctcctctata aaagagattc
     6841 accaatatca ttggaaagag accataaaag aaaaggagtt ttttaggaag ccctctcaat
     6901 aataagaaag ataagcctat gccgtacaag ggttccataa aataagatag gtaaacattt
     6961 cctactatat agctaatcat cacaaaaaca aaggccaaca gtatcttaaa aagaaaggcc
     7021 ttaaaaatcc tctcgaaagc aagatcaatt ccatccacct taaagaagat gacaatttct
     7081 agtccattag taacaagtgt atacaacaat atccaagcaa tgttcataaa ttctcctagc
     7141 tcagtgtaat ttattgatgg cctcagacac ttccctgacc ttataacggg cgattagaca
     7201 acttccacca ttgggaaaga aaagcagttt ttctttctta tccaaatgca ccacatttgc
     7261 aggattgatg agaaaagagc ggtggcactg caagagacgg ggctcctgct tgaaaacctc
     7321 ctctaaactc gctgtaaatt ccagcctgtc tgtcttggta tagagaataa cacgatgggc
     7381 tctgggcgac gtttcgagat agtaaacctc tttaaaagga tactgaaatt gggcaaattt
     7441 tgatttaaag taaaagcaat cttccgccag acttttacta tcttgactat tggcatagag
     7501 gagggctgtc tcgatccgag attcaaactc ctctgctgac aaggccttat caatgtagtc
     7561 caaagcagac acttggtagc gaaaagacag gggcataaac tccgagtgag tcgtcacaaa
     7621 gacaatcagg gcataaggat cccgatcccg aatctttcta gccacttcca gtcccttcat
     7681 ctcttcattt cgaatctcaa tatccaaaaa gaatagctga tgggccccct tctcatgcac
     7741 ttcagccagc agttggtccg gcttgccaaa tacctcaaaa gagctaggaa tgatatgatg
     7801 tgctttcaaa agtttctcaa tcgtcgtttc aattctagtc tgttgggaaa aatcatcctc
     7861 taaaacaaat attctcatct tcttactctc cctctttcaa ccatttttga cgaatttctc
     7921 tatagcgacg tctggcatac ttgacagcgt attgaccttc ttctccgaga aaaaggattc
     7981 tttcttgaaa atcaatcgat tttaatttat caagattaac caaacaattt cgatgacatc
     8041 tcatcaaggt ttccccacat tggttctcaa gattacttaa attttgaagc atattaaaac
     8101 tagcttcttc tgtaacaatc tgtacggtat gggctttagt tggatgtgtt tggatatagt
     8161 agatatcgtc gatgtttact ttatagactg ttttctgcgt ctgaataatc atatatttca
     8221 ttggattctc ctcctaagaa aagaataaca gaaaaggtct agcccaagca cacccaatcc
     8281 taaacagtct ttgaaaactc ctaaaaggat tattttctac aacatcatga tgagcttaca
     8341 actattttat cataaaattc actcagcgca attcaagaca tttcaatgac aattaaagat
     8401 ttgaataaaa aaaaagaatt aaaagtgata aactaacagt atcaaaacac agttgccaga
     8461 agtaagactg gcacccagat taaaggaggc attcccatga cagatacaga ccccatcaaa
     8521 agagctcata ctttgattac tgacttaaac aaagcctacc aagcatgcaa acaggcaagc
     8581 gctgacgacg tccgctttca ggagcaatta aactctattc ttggttttct agccaagact
     8641 gaaacagtgg ataatcgatt cttgattgaa ctagaaaaat tttaccagac ttccagtctt
     8701 ctcatgggac tcagcgctct tgatccagat gctccaactc gcgccgcttg gcgggcctat
     8761 gaccgcttcc actttgacca agtcaagacc aagttaatac tcaatgaaaa tcaaagagca
     8821 aactaggaag ctagccgcaa gctgtacttg agtacggtaa gacgacgctg acgtggtttg
     8881 aagatatttt cgaagagtat aagtctctac ggaccaacca ttatcctgta gtaacaaaaa
     8941 agaagctgag acagactgaa ctcaacttct tttttagtgt cgtatcagca atgttagtcc
     9001 tgcatctgac gttttacctg ataaggcaaa tacaagacta gtaaaaccaa accagctcct
     9061 agtaaggcta gaagggctag tttttcttgg aaggtaatca acccaacaac taattccaca
     9121 agtaaaacaa aactggtcaa tcctcgaact acctcctgta agcctttttc cttttgcccc
     9181 ttgtccagcg gaaagagttg ggtcaaatac tggtagtcaa aggcatgata gagggccagc
     9241 aactggaaga gcaagaggta gttaaagaga actaccactg ctgtcgcaat ccaagcttgc
     9301 tcgataaaaa cctgcgccag tacggaaagt aagagaagac gaagactgag agcaaagagg
     9361 tcgccatttc gcagataaga acgcagatag agattttgcc aaatcttccc aggcaccttc
     9421 tgaacagcct ttaaaataaa gtccagatag gcacgacgct taacgctgtt tgaaattccc
     9481 ttgacctgcg taaagagggc aaagaaacga agcaagactt gcttacgctt gctttcttga
     9541 gaaataagat agtcccagtc cagtccagtt tcagtgaaaa atttgctggc cttttgacaa
     9601 aagtggaaat attttcctac ccccaataaa agcacataga gcagaaaaac tggcaagcca
     9661 taacccattg ctaaaaataa aggcgcaaat aacagcaaga aaagggtctg tacaaagagc
     9721 caaaagacta gggaaatgcc agtttgacgc ttgagatgga gcttgatttc ctcttctccg
     9781 actaagagaa agagcttgtc tggagcctcc atataggtgg caattcctcc ccaaagtaaa
     9841 agtaaaacag acgtaattcc tacaaacaaa aggataggcc aatgattttc aggaaaatgt
     9901 tgtaagagtt gactgtactg gtaggctaga aagcccaaca ggacaagcag gaacaagaca
     9961 aagtggtcat tgagcacata gcgcagataa ccaagacact ccttacgaaa ggcctgcttt
    10021 ctctttaaaa acaagtcttt cataggtcct cctcttttgt cagagccaag taaatatcat
    10081 tcaaactagc ctcaggcata tcaaaggctt cgcgtagttg caggagattg cctttggcac
    10141 gcacctctcc cttgtgaaga atgacaaagg catcacacat cttctccgcc gaatccagca
    10201 cgtgggtact catgagaata gacttgccct tttgcttctc cacttccaaa agctgaatca
    10261 aatcagaaat agctagcgga tcaagaccaa ggaaaggctc atccacgatg aaaagacttg
    10321 gatccaccac aaaagcacag ataatcatga ccttctgctt catccctttt gaaaaatgaa
    10381 cagggaacca gtctaatttc tggtccagac ggaacatctt taacaagggc tctactcgtt
    10441 cgaaagccac tttttgctca ataccgtaag ccatagcaac cgtttcgata tgctctctga
    10501 gggtcaattc ctcatacaga ctaggcgtct caggaatgta gccaatctgc ttgcggtagc
    10561 tagtcgcatc tccttgcaga gtcaggccat tgatattgat ggagccacta taaggtgcca
    10621 acagaccgat aatctcattg atcgtcgttg atttcccagc accattgaga ccaatcaaac
    10681 cgaccaactg cccactttca acagtaaagg acacatcttt caaaacagga acatgaacat
    10741 agccacctgt caggttttta atttctaaca tattttctcc aaatctggta taatgtagct
    10801 atattatatc aaaattcagt acagtagagg tagattttat gtcagattgc attttttgta
    10861 aaatcatcgc aggggaaatt cctgcttcaa aagtatatga agatgagcag gtccttgcct
    10921 ttcttgatat ctctcaagta acactaggac acaccttggt cgtgccaaaa gaacactatc
    10981 gcaatctttt ggagatggat gctacgagcg ccagccaact ctttgcccaa gtaccaaaag
    11041 tagctcaaaa agtcatgaaa gtcactaagg ctgctggtat gaatatcatt tccaactgtg
    11101 aagaagtcgc tggtcaaaca gtttttcata ctcacgttca ccttgtgcct cgctacagtg
    11161 ctgacgatga cctcaagatt gattttatcg cccacgaacc agactttgac aaacttgctc
    11221 aagtcgctga aaccatcaaa aacgcttaag gagttgctat gaaattatcc aacctactgc
    11281 tatttgcagg agctgcagcc ggaagttatc tggttacaaa aaatcgccaa accatcacag
    11341 atgaagtctt gaataccact gaccgcgttc aagctatcaa ggacgatgtg gatattatcc
    11401 aaaacagcct gcaaatcatt aaccagcaaa aagaacttat caaggaatac caagaagact
    11461 tgacttacaa gtttaaggtc ttggaaaagg atatccagac tagactagct gtgataaaag
    11521 aaatgcaggg aactgaagat aagtaaaaag agccccccgg ctctttttta aaacgtaaac
    11581 aagttatagt gaattgaatt tagaatagca caccatagtt tctaaagcat tgttagagat
    11641 tactttaaaa tcctcttatc aatttgttca tattctattt caatctatta tatatatccc
    11701 atcaactatg catcataatt taggtaactc atactcaata aaaatcaaaa agcaaactag
    11761 aaagctaggc acagactgct caaaacaccg ttttaaggtt gtggatagaa ctgacgaagt
    11821 cagctcaaaa caccgtttt
//
LOCUS       DBERPV010000046        11779 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.46, whole genome shotgun sequence.
ACCESSION   DBERPV010000046 DBERPV010000000
VERSION     DBERPV010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11779
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.46"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            204..2495
                     /gene="pcrA"
                     /locus_tag="ACL8C7_001828"
     CDS             204..2495
                     /gene="pcrA"
                     /locus_tag="ACL8C7_001828"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HGS1395975.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTTYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGPGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            2538..3218
                     /gene="radC"
                     /locus_tag="ACL8C7_001829"
     CDS             2538..3218
                     /gene="radC"
                     /locus_tag="ACL8C7_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HGS1395976.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3215..3904)
                     /locus_tag="ACL8C7_001830"
     CDS             complement(3215..3904)
                     /locus_tag="ACL8C7_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HGS1395977.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(3922..4563)
                     /locus_tag="ACL8C7_001831"
     CDS             complement(3922..4563)
                     /locus_tag="ACL8C7_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HGS1395978.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(4646..4861)
                     /locus_tag="ACL8C7_001832"
                     /pseudo
     CDS             complement(4646..4861)
                     /locus_tag="ACL8C7_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
     gene            complement(4869..5216)
                     /locus_tag="ACL8C7_001833"
     CDS             complement(4869..5216)
                     /locus_tag="ACL8C7_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HGS1395979.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5221..6336)
                     /locus_tag="ACL8C7_001834"
     CDS             complement(5221..6336)
                     /locus_tag="ACL8C7_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGS1395980.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEANNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKENLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6346..7305)
                     /locus_tag="ACL8C7_001835"
     CDS             complement(6346..7305)
                     /locus_tag="ACL8C7_001835"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGS1395981.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(7418..7987)
                     /locus_tag="ACL8C7_001836"
     CDS             complement(7418..7987)
                     /locus_tag="ACL8C7_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HGS1395982.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8115..8786
                     /locus_tag="ACL8C7_001837"
     CDS             8115..8786
                     /locus_tag="ACL8C7_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HGS1395983.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            8770..9588
                     /locus_tag="ACL8C7_001838"
     CDS             8770..9588
                     /locus_tag="ACL8C7_001838"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HGS1395984.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            9585..10481
                     /locus_tag="ACL8C7_001839"
     CDS             9585..10481
                     /locus_tag="ACL8C7_001839"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGS1395985.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEKGFETLEAIELPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     DIRLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLDDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            10525..11499
                     /gene="pta"
                     /locus_tag="ACL8C7_001840"
     CDS             10525..11499
                     /gene="pta"
                     /locus_tag="ACL8C7_001840"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HGS1395986.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
BASE COUNT         3420 a         2267 c         2544 g         3548 t
ORIGIN      
        1 actaggattc tagttttgca ggaagtctat tgaggtattg agctagttta tgaaaaaatt
       61 gggtgaaaag tcgagtgttt tagaaaccca cagtgtagta ttctagtttc aatctactat
      121 attttgctac tccccgtaaa gtttctattt tccctgattt ctgatataat agaaatattg
      181 acttcaagag taaggaagag aagatgaacg cattattaaa tggaatgaat gaccgtcagg
      241 ctgaggcggt gcaaacgaca gaaggtccct tgctaatcat ggcaggggct ggttctggaa
      301 agactcgtgt tttaacccac cgtatcgctt atttgattga tgaaaagctg gtcaatcctt
      361 ggaatatctt ggccattacc tttaccaaca aggctgcgcg tgagatgaaa gagcgtgctt
      421 atagcctcaa tccagctact caggactgtc tgattgcgac cttccactcc atgtgtgtgc
      481 gtattttgcg tcgcgatgcg gaccatattg gctacaatcg taattttaca attgtggatc
      541 ctggtgaaca gcgaacgctc atgaaacgta ttctcaaaca gttgaacttg gatcctaaaa
      601 aatggaatga acgaactatt ttggggacca tttccaatgc taagaatgat ttgattgatg
      661 atgttgctta tgctgcccaa gctggcgata tgtatacgca aattgtggcc cagtgttata
      721 caacctatca aaaagaactt cgtcagtctg aatccgttga ctttgatgat ttgattatgc
      781 tgaccttgcg tctctttgat caaaatcctg atgttttgac ctactaccag caaaaattcc
      841 aatacatcca cgttgatgag taccaagata ccaaccacgc tcagtaccaa ttggtcaaac
      901 tcttggcttc ccgttttaaa aatatctgtg tggttgggga tgcggaccag tctatctacg
      961 gttggcgtgg tgctgatatg cagaatatct tggactttga aaaggattac cccaaagcta
     1021 aggttgtttt gttggaggaa aattaccgct caaccaaaac cattctccaa gcggccaacg
     1081 aggttattaa aaataataaa aatcgccgtc ctaaaaatct ctggactcaa aacgctgatg
     1141 gggagcaaat cgtttactat cgtgccgatg atgagctgga tgaggctgta tttgtagcca
     1201 gaaccatcga tgaacttagt cgcagtcaaa acttccttca taaggatttt gcagttctct
     1261 atcggactaa tgcccagtcc cgtacaattg aggaagccct gctcaagtct aacattcctt
     1321 ataccatggt tggcggaacc aaattctaca gccgtaagga aattcgcgat attattgctt
     1381 atctcaacct tattgctaat ttgagtgaca atattagttt tgagcgtatt atcaacgagc
     1441 ctaaacgtgg aattggtcca ggtacagttg agaaaatccg tgattttgca aatttgcaaa
     1501 atatgtctat gctggatgct tctgctaata ttatgttgtc tggtatcaag ggtaaggcag
     1561 cccaatctat ctgggatttt gccaatatga tgcttgattt gcgggagcag ctagaccact
     1621 taagcattac agagttggtt gagtccgtcc tagaaaaaac aggttatgtc gatattctta
     1681 acgcccaagc gactctagaa agcaaggcac gggttgaaaa tatcgaagag tttctttctg
     1741 ttacgaagaa ctttgatgac accacggatg tgacagaaga ggaaactggt ctggacaaac
     1801 tgagtcgttt cttaaatgac ttggctttga ttgccgacac agattcaggt agtcaggaga
     1861 catcagaagt gaccttgatg accctgcatg ctgccaaagg tctcgaattt ccagttgtct
     1921 ttttgattgg gatggaagaa aatgtctttc cacttagtcg tgcgactgaa gatccagatg
     1981 aattagaaga agagcgccgt ctagcctatg taggtatcac gcgtgcagag aaaattctct
     2041 atctgaccaa tgccaactca cgcttgcttt ttggtcgtac caattataac cgtccgactc
     2101 gttttattaa cgaaatcagt tcagacttgc ttgagtatca aggtctggct cgtcctgcaa
     2161 atacaagctt taaggcatca tatagcagtg gtagtatttc ctttggtcaa ggtatgagtt
     2221 tggctcaggc tcttcaagac cgtaaacgcg gtgctgcccc aaaatcaatc cagtcaagcg
     2281 gtcttccatt tggtcaattt acagctggcg caaaaccagc atctagcgag gcaaattggt
     2341 ccattggtga tattgctctc cacaagaaat ggggagaggg aaccgttctg gaagtttcag
     2401 gtagcggtgc taggcaggaa ttgaaaatca atttcccaga agtaggtttg aaaaaacttt
     2461 tagccagtgt ggctccaatt gagaaaaaaa tctaattttc catccttctc acgaataata
     2521 aagtgaggag gatttttatg tacagtattt cattccaaga agattcacta ttaccaagag
     2581 aaaggctggc caaggaagga gttgaagcgc ttagtaacca agagttgcta gctattttac
     2641 tcaggacagg aacacgtcaa gctagcgttt ttgaaattgc ccaaaaagtc ttgaacaatc
     2701 tttcaagcct aacggatttg aaaaaaatga ccctgcagga attgcagagt ttgtctggta
     2761 ttgggcgtgt taaggccata gaattacaag ctatgattga actggggcat cgtattcaca
     2821 aacacgagac tcttgaaatg gaaagtattc tcagcagtca aaagttggcc aagaagatgc
     2881 agcaggaatt aggggataaa aaacaagagc acctggtggc actctatctc aatactcaaa
     2941 atcaaatcat ccatcagcag accattttta tcgggtctgt aactcgtagt atcgctgaac
     3001 cgcgagagat tcttcactat gcaatcaagc atatggcgac ttctcttatc ttggtccaca
     3061 atcatccttc aggagcggta gcgcctagcc aaaatgatga tcatgtcact aaacttgtta
     3121 aagaagcctg cgaactgatg gggattgttc tcttggacca tttgattgtc tctcattcta
     3181 attactttag ttatcgtgaa aagacagatt taatctaaag ttcattaacg acatagtcaa
     3241 agagtttttt atctttggga cgattttcaa aaagaagttc tggatgccat tggacaccga
     3301 gaaaggcgac atcatccgta ctcatgacag cctcaatgat accatcttta ggatcatgag
     3361 ccacaacttt taaatttggt gctaagtcct tgatgctctg gtggtggaag gagttgatat
     3421 gagagatttc tccatagatt tcttggagaa cggtatctgg ttctgtcacc aagcgttgag
     3481 ttgtgtactc aacagaagaa tcctgccaat ggtcttcgat atcttggtac aaagttccac
     3541 ccatggcaac gttaaagagt tgggtaccac ggcagacaga gaaaatgggc tttttctgtt
     3601 taatagcttc cttgatgagg gccagttcga agatatctct ttgaaggtga tagtcatcgc
     3661 tatcaatggt tttgggttcg ccatagaatt ttggatcgac attttgccca cctgtcaaga
     3721 tgagcttgtc aatcaaactg atatagtggc aggccatttc ttgatcacca atcggtagga
     3781 tgatgggaat ccctccagca tctttaacgc cttcaacaaa gccttttgct gcgtagctca
     3841 tcatgatgtc atcatctgga tgagcttttt cgtttcctgt aatcccaata actggttttt
     3901 tcataaaatg attttcgctt tctaatcctc ttttcgcatg aagtagagga gggtttggag
     3961 ttcacttgtc aaatcgacat actgaacgac cacgtctttt ggtaaatgca gatggactgg
     4021 tgaaaaactg agaattcctt tcacaccagc atcaaccaag agattagcaa cctcttgtga
     4081 cttgacgctg ggaacagtta ggatagcagt cttcacatca gcatccttga ttttatcctt
     4141 gatctgagaa atcccgtaaa tgggaatccc gtcaggagtt tgggtaccga cttcaggatg
     4201 gtcgtctagg tcaaaggcca tgataatctt catcttgtta cgttcgtgga agcggtagtg
     4261 gagaagggca tggcccatat ttccaatacc aaccagcatg acattggtaa tagagttgtc
     4321 attgagcaaa tcggcaaaaa atgtcattag ttttttgaca tcatagccaa aaccacgacg
     4381 accaagttca ccaaaatagg aaaaatcacg acgtacggtc gctgaatcaa taccgatagc
     4441 ctctgcaatt tgcttagagt tggcacgttc aatcttttct gcatgaaatc tcttaaaaat
     4501 tcgatagtag agagagagtc tttttgctgt agcttttgga atagcaaact gtttatcttt
     4561 cacaaaatca caacctttct attcttctat tttatagaaa cattgtgaaa aaatcaacaa
     4621 aaataagaaa aaactaagaa aaatcttagt tttgatgtaa aaaatctgca tgagatagaa
     4681 aacggtagag gtctccgacc agaccctgat aaacttttta gcccctaaaa gtcagagaag
     4741 tcacataaag tgtatctggt aaggttacac atcctgacaa agtcaacatg agagcctcat
     4801 gatcctcata cttgagagta cgctctacat gatagcagtc cttataggtc agttcaaaca
     4861 ttttggctct atctttccga ttttgtaaag acaccacgtt ctaccaagct atccatgagg
     4921 aagtagaatt tttcctgatg aatatggtgg tcttctgatt tgaaaatatc aactagacga
     4981 aggccaaact tgtcagtgat attgatttta gcccctgtaa gttccttgtt aatgatgatt
     5041 ttgagttgga agccttcacc gctgtttggc actttttcca aaaggcgagt cagttcatag
     5101 ttaccaacct tagtttcaaa aaaggtgtta tctttgaggg tgaatttttt aacagaagga
     5161 ctaagagtgt aatcgtaacg acaatttttt aactgaatga ttttttcaaa tgccatatgg
     5221 ctaacctccg ataatttctt ttaaggtttt tgcgagggtt tgtaggtctt caacggtatt
     5281 ttgtggcgac aaactgatgc gaagggattc cttcaagcgt tctgaatttg cgccatacat
     5341 ggcttcaaga acatggctgg attggacaac gcctgcagta caggctgagc cagtagagat
     5401 tgaaattcca gctaaatcta gccgaaggag taagaggtca tttttctgac caggaaatcc
     5461 aatattgaga acataaggga gatgatgttt tcctctattc aagtaatact gaatgccctc
     5521 cagctctgcc agaaaggcag tttctagatt ttgtacatgt tgaaaatgtt cttcttgttt
     5581 ttctaggttt tcttttaggg ctgcaaccat gcctacgatg gcaggcagat tttcagttcc
     5641 tgcacgtttt ttctgttcct ggtctccgcc atgtagatag gaatcaaagt ccatgctaga
     5701 tgcgtagaga aaaccgattc ccttaggacc atggaatttg tgggcagaag cagtgagaaa
     5761 atcaatgccc aattcttctg aatgaattgg gattttacca atagcctgaa ctgcatcaac
     5821 atgataggca gcagggtgtt gcttgagtat ttggccaatt tcagcgatgg gcagtaggtt
     5881 tcctgtctca ttattggcaa acatggtaga aaccaaaatc gtatcgtcac gtaaagcctt
     5941 ttgaatttgc tgggctgtga tttcttgatt ttctggctgg ataatggttg cttcaaaccc
     6001 aaagtgttga accaagtaat caattgtttc aaggacagca tggtgctcga tggcagttgt
     6061 gatgatatgt tttccttgtt cttggtgacg aagacagtag ccaatgatgg tagtattatt
     6121 ggcttcagtc ccaccagaag tgaaaaagat atgttgaggt tttgtcctta gtaactgggc
     6181 tagttcctga cgggcttctc gcaagagttt gccagcttga cgaccatgac catgaatact
     6241 agaaggattt ccgtgggttt cttgcataac cttggtcata gctgaaatag caactgctga
     6301 cataggagtc gttgcagcat tgtccaaata aatcaaagaa tcaccttatt tctttttatt
     6361 gtaggcaaag agtgggctga ctggttttct ttcgtgaata cggacgatag catcgccaat
     6421 taactcacta gcagtgatgt agcatacatt tttaggagtt ttttcttttg ttgctactga
     6481 atcagtcaca agaatttctt taatattagt attgtcaaga agctcagcag ctccctcgac
     6541 gaagagaccg tggctagaaa cagcataaat ttctgtagct ccttcacgtt caacgatttt
     6601 agaagcttca gagaaggtac gtcctgtatt taaaatatca tcaatcaaga tagctttctt
     6661 accttcaaca tcaccaataa tataaccttc gttacgagtt gcatcgtctt gagggtaatc
     6721 gataatggcg ataggagcat caagatattc agccaggcta cgcgcacgtt tgacacctga
     6781 atttttaggg ctaacgacaa caacatctga accaagcaat cctttatcgc agtaatgttt
     6841 tgcgaatagg ggaacagtga aaagattatc cactggaata tcaaagaaac cttgaacctg
     6901 aacggcatgc aaatcaagag tcaggatacg atcaactcca gccttaacca gcatattggc
     6961 aactagtttt gctgtaagtg gctcacgagg acaagcaatg cggtcttgac gtgcatagcc
     7021 aaaatatgga aggacaacgt tgatactgtg ggcacttgca cgcacacaag catcgaccat
     7081 gattaacaat tccattaggt ggttgttgac agggaaactt gttgattgga tgatgtaaac
     7141 atcataacca cggacacttt cttcgatatt tacttggatt tctccgtctg aaaattgacg
     7201 tgatgatagt tttccaagtg ggacaccaac agcttgggca attttctgtg caatctcttg
     7261 gttagagttg agtgcgaaaa gtttcatgtt ttttctatct gacattatag accgtcctct
     7321 gtaaacttta taaatcctag ttatatttac cttacatata tgaactaggg tttgtgtatt
     7381 tttatctttt ctattttacc aaaaaatgga gattatttca gctatttttc atacttttga
     7441 caaatcgaac caattttgaa ggagcttttt gataggaaat ctgatttttc tctaaaaatt
     7501 gtcggaaatc ctgtttgcct tgctcatgat tttccacttc aagctccaat tcgtaatctg
     7561 ttatatcaaa gtatcggctc tgatccagtg ccatgagacc aatagctgtt ttcatttcat
     7621 agcgaagcgt tgttagacaa ccaagaacct gccagttctt actttggata ccatgtttcg
     7681 ccaattcatc cagtactagc ccttgaggaa gttcttcctt actcagatag ttctcagcat
     7741 cttttagttg caatttttgg ttgtattcca tgtttccaac actctgcggg actttgagtg
     7801 tcaactcagc ccagtcttca aaggttcgaa tgcgcatagc gactttcttt tctcgcagtt
     7861 caaaatcagg cgtgtcgatg tagtaatttg tttgaagaac aggagtgaca cctgtgaact
     7921 ggtcttttag acgattgtat tcatcttttt tcaatagtgt tttcaattca atttctaaat
     7981 gtttcatttt tcttaccttt ttttatcgtt gaaagcggat ttatggtata ataagcattg
     8041 tatttattgt atatgaatct ggagaaaaaa tcaaagatat ttttgacgga taatatgaga
     8101 acaagggaga atatatgacc ttagaatggg aagaatttct agatccttac attcaagctg
     8161 ttggtgagtt aaagattaaa cttcgtggta ttcgtaagca atatcgtaag caaaataagc
     8221 attctccaat tgagtttgtg accggtcgag tcaagccaat tgagagcatc aaagaaaaaa
     8281 tggctcgtcg tggcattact tatgcgacct tggaacacga tttgcaggat attgctggct
     8341 tacgtgtgat ggttcagttt gtagatgacg tcaaggaagt agtggatatt ttgcacaagc
     8401 gtcaggatat gcgaatcata caggagcgag attacattac tcatagaaaa gcatcaggct
     8461 atcgttccta tcatgtggta gtagaatata cggttgatac catcaatgga gctaagacta
     8521 ttttggcaga aattcaaatt cgtactttgg ccatgaattt ctgggcaacg atagaacatt
     8581 ctctcaacta caagtaccaa ggggatttcc cagatgagat taagaagcga ctggaaatta
     8641 cagctagaat cgcccatcag ttggatgaag aaatgggtga aattcgtgat gatatccaag
     8701 aagcccaggc actttttgat cctttgagta gaaaattaaa tgacggtgta ggaaacagtg
     8761 acgatacaga tgaagaatac aggtaaacga attgatctga tagccaatag aaaaccgcag
     8821 agtcaaaggg ttttgtatga attgcgagat cgtttgaaga gaaatcagtt tatactcaat
     8881 gataccaatc cggatattgt catttccatt ggcggggatg gtatgctctt gtcggccttt
     8941 cataagtacg aaaatcagct tgacaaggtc cgctttatcg gtcttcatac tggacatttg
     9001 ggcttctata cagattatcg tgattttgag ttggacaagc tagtgactaa tttgcagcta
     9061 gatactgggg caagggtttc ttaccctgtt ctgaatgtga aggtctttct tgaaaatggt
     9121 gaagttaaga ttttcagagc actcaacgaa gccagcatcc gcaggtctga tcgaaccatg
     9181 gtggcagata ttgtaataaa tggtgttccc tttgaacgtt ttcgtggaga cgggctaaca
     9241 gtttcgacac cgactggtag tactgcctat aacaagtctc ttggcggtgc tgttttacac
     9301 cctaccattg aagctttgca attaacggaa attgccagcc ttaataatcg tgtttatcga
     9361 acactgggct cttccattat tgtgcctaag aaggataaga ttgaacttat tccaacaaga
     9421 aacgattatc atactatttc ggttgacaat agcgtttatt ctttccgtaa tattgagcgt
     9481 attgagtatc aaatcgacca tcataagatt cactttgtcg cgactcctag ccataccagt
     9541 ttctggaacc gtgttaagga tgcctttatc ggtgaggtgg atgaatgagg tttgaattta
     9601 tcgcagatga acatgtcaag gttaagacct ttttaaaaaa gcacgaggtt tctaagggat
     9661 tgctggccaa gattaagttt cgaggtggag ctattctggt caataatcaa ccgcaaaatg
     9721 caacgtatct attggacgtt ggagactacg ttaccattga cattcccgct gagaaaggct
     9781 ttgaaacctt ggaggctatt gagcttccat tagatattct ctatgaggat gaccactttc
     9841 tagtcttgaa taaaccctat ggagtggctt ctattcctag tgtcaatcac tctaatacca
     9901 ttgccaattt tatcaagggt tactatgtca agcaaaatta tgaaaatcag caggttcaca
     9961 ttgttaccag actagatagg gacacttctg gcttgatgct ctttgccaag cacggttatg
    10021 cccatgcacg attagacaag cagttgcaga agaaatctat cgagaaacgc tactttgctt
    10081 tggttaaggg agatggacat ttggagccag aaggggaaat tattgctccg attgcgcgtg
    10141 atgaagactc cattattacc agacgggtgg ctaaaggtgg aaaatatgcc catacttcct
    10201 acaagattgt agcttcttat ggaaatatcc acttggtcga cattcggctg cacactggtc
    10261 gaacccacca aattcgagtc cacttttctc atattggttt tcctttgttg ggcgatgatt
    10321 tgtacggtgg tagtctggac gacggcatcc aacgtcaggc cctgcattgc cattacctat
    10381 ccttttatca tccattttta gagcaagatt tgcagttaga aagtcccttg ccggatgatt
    10441 tcagcaacct tattacccag ttatcaacta atactctata aaaactgttt cagagtataa
    10501 ttattatctt aaaggagaaa actcatggaa gtttttgaaa gtctcaaagc caaccttgtt
    10561 ggtaaaaatg ctcgtatcgt tctccctgaa ggggaagagc cacgtattct tcaagcgact
    10621 aaacgtttgg taaaagaaac agaagtgatt cctgttttgt taggaaatcc tgaaaaaatt
    10681 aaaatttatc ttgaaattga agggatcatg gatggttatg aggtcatcga ccctcaacat
    10741 tatcctcaat ttgaagaaat ggtttctgcc ttggtggagc gtcgcaaggg caaaatgact
    10801 gaagaagatg tacgcaaggt tttggttgaa gatgtcaact actttggtgt gatgttggtt
    10861 tacttgggct tggttgatgg aatggtgtca ggagcgattc actcaacagc ttcaacagtt
    10921 cgtccagctc tacaaatcat caaaactcgt ccaaatgtaa ctcgtacttc aggagccttc
    10981 ctcatggttc gtggtacgga acgttaccta tttggagact gtgccattaa catcaatcca
    11041 gatgcagaag ccttggctga aattgccatc aactcagcaa tcacagctaa gatgtttggc
    11101 atcgaaccta aaattgccat gttgagctat tctactaaag gttcagggtt tggtgaaagc
    11161 gttgataagg tcgttgaagc aactaaaatt gctcacgact tgcgtcctga ccttgaaatc
    11221 gatggtgagt tgcaatttga tgcagccttt gttcctgaaa ctgcagctct gaaagctcct
    11281 ggaagtacgg tagctggtca agcaaatgtc ttcatcttcc caggtatcga ggcaggaaat
    11341 atcggttaca agatggctga acgcctgggt ggctttgcgg ctgtaggacc tgttttgcaa
    11401 ggtttaaaca agccagttaa tgatctttct cgtggatgta atgcagatga tgtttacaag
    11461 ttgaccctca tcacagcagc tcaagcagtt catcaatagt gaaaactata aagcgatata
    11521 ctatgctata ctgtagttat gaaactatgt acgaaaagca ctgccattaa ttcctgagaa
    11581 ctaaattact gattggtgtc aaaaaggaaa acttccaagc gatgatatcc tgtctataca
    11641 cgacctatag aaatctgtaa tatgtatgtc cgtaaaacga taatttccct ttttgatttt
    11701 aaatgagtat gaaaagagaa ttttttcatg agaaaacgca taatattaag tgtcttgaca
    11761 cctgctatta tgcgttttc
//
LOCUS       DBERPV010000047        11115 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.47, whole genome shotgun sequence.
ACCESSION   DBERPV010000047 DBERPV010000000
VERSION     DBERPV010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11115
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.47"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(52..1188)
                     /gene="dnaJ"
                     /locus_tag="ACL8C7_001841"
     CDS             complement(52..1188)
                     /gene="dnaJ"
                     /locus_tag="ACL8C7_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HGS1395987.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(1590..1946)
                     /locus_tag="ACL8C7_001842"
     CDS             complement(1590..1946)
                     /locus_tag="ACL8C7_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HGS1395988.1"
                     /translation="MSVLDEEYLKNTRKVYNDFCNQADNYRTSKDFIDNIPIEYLARY
                     REIILAEHDSCIKNDEAVRNFVTSVLLSAFVSAMVPAMISLEIQTYKFVIPFIIGMIW
                     TVVVFLMINWNYIGKY"
     gene            complement(1948..3771)
                     /gene="dnaK"
                     /locus_tag="ACL8C7_001843"
     CDS             complement(1948..3771)
                     /gene="dnaK"
                     /locus_tag="ACL8C7_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HGS1395989.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKTKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(4251..4775)
                     /gene="grpE"
                     /locus_tag="ACL8C7_001844"
     CDS             complement(4251..4775)
                     /gene="grpE"
                     /locus_tag="ACL8C7_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HGS1395990.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(4802..5836)
                     /gene="hrcA"
                     /locus_tag="ACL8C7_001845"
     CDS             complement(4802..5836)
                     /gene="hrcA"
                     /locus_tag="ACL8C7_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HGS1395991.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(6000..6509)
                     /locus_tag="ACL8C7_001846"
     CDS             complement(6000..6509)
                     /locus_tag="ACL8C7_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HGS1395992.1"
                     /translation="MNSRVEFRIFTIVDLDKKEEYLHEMHLKGWRYRTSRFGLFYFEQ
                     GQPDDVIYRIYDSRFLKEHKRELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCIATFLGGLVVCMSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            7117..9450
                     /gene="hsdR"
                     /locus_tag="ACL8C7_001847"
     CDS             7117..9450
                     /gene="hsdR"
                     /locus_tag="ACL8C7_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0015666 - restriction
                     endodeoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EcoAI/FtnUII family type I restriction enzme
                     subunit R"
                     /protein_id="HGS1395993.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFKPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDTNGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAMVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSITEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGEPVKVLE
                     TGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTANKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            9463..10926
                     /locus_tag="ACL8C7_001848"
     CDS             9463..10926
                     /locus_tag="ACL8C7_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HGS1395994.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            10926..>11115
                     /locus_tag="ACL8C7_001849"
     CDS             10926..>11115
                     /locus_tag="ACL8C7_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease"
                     /protein_id="HGS1395995.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDD"
BASE COUNT         3388 a         2185 c         2154 g         3388 t
ORIGIN      
        1 tacccatggc aaggcaacgc tgacgtggtt tgaagagatt ttcgaagagt attattctcc
       61 atcaaaggca tcttttatat ggtcaaagaa gccttttttc tttggattta ctttcaagtc
      121 accagcagcc gcgaattctt tcaaggctac tttttggcgg tcgttcaagc ctgtcggtgt
      181 tacgacatta acagtaacgt attggtcacc aactgcaccg ccacgaaggc tcggtgcccc
      241 cttactacgt aggcggaatt tcttaccagt ctgagttccc tctggaataa ccaattcaac
      301 atcaccgtga acagttggaa tatctactgt atcaccaaga gccgcttgga caaagttgag
      361 gttgagattg tagaagatag tcgttccttc acgttcaaac ttgtcgctag cttctacaga
      421 aactactaca tacaagtccc cataaggtcc accgttaaag cctgcttcgc cttgaccagc
      481 gaggcgaatt tgttgacctg tttccacacc agcagggatt ttcacatgta cgctatgagc
      541 ttgtttctca tgacctgttc catgacaggt tgtacatgga tatttgattt cttttcctcg
      601 accgtgacag acatcacagg ttacttggcg acgcatcata ccaagaggag tctgcgtatc
      661 gacgttaatg acaccagcgc catgacagcg tccacaagtg actggacttg tccctggctt
      721 agcaccagag ccattacatg tacgacagcc agcttcacga tgatacttaa cttccttctc
      781 agttccgaag atagcttctt caaaggtcaa attgacacga tactggagat catctccttg
      841 gcgaggagcg tttggattgc gcgaagaacc gcctccgccg aagaaacttg agaaaatatc
      901 ctcaaaacca ccgaagccac ctgccccatt gaaaccaccg aaaccaccag ctccaccaaa
      961 accaccattg gcgcctgcag caccatactg gtcataggca gcacgttttt ggtcgtcact
     1021 caaagtctca taggcttctt gaacttcctt gtacttgtcc tcagcaccag gctccttgtt
     1081 gatatctggg tgatattttt tggaaagctt acgataagcc tttttgattt cgtctgccga
     1141 agcgtttttg gataccccca gacgatcata aaattcagta ttgttcataa ttcaagatac
     1201 aaagggcgtc aaacggacac agccatctag gagttttgac gacggacgct tacgtcctag
     1261 aaaaaactat ctttttggca cagtccatag cccgtgttca gttacgaaca cccttattcc
     1321 tttctattga tgttctgaat cgaaccacca tttaggtcgg gttcaattcc tttcttttat
     1381 atttagtaag aaattctgaa acccgtgttc agttacgaac actctttgtt cctttctatt
     1441 gatgagacaa aacccaaaca aatgagattc cgtccctttt tatcgaaaaa cagaggctgg
     1501 gttgcaacct ctgcaaataa gtaaattaac tttattttga ttttaaatat cctataagta
     1561 cagaaatatt tatatatttt tgtctcttct tagtatttgc ctatataatt ccaattgatc
     1621 ataagaaata caactactgt ccaaatcata ccaattatga acggtattac aaatttatat
     1681 gtttgtattt ctaatgatat catagctggt accatcgccg atacaaatgc agacaacaat
     1741 actgaggtaa caaaattcct taccgcttca tcatttttga tacaactatc atgttcagct
     1801 aatataattt ctctatatct agctaaatat tctattggaa tattatcaat aaaatctttt
     1861 gatgttctat agttatcagc ttgattacaa aaatcattat aaacttttcg tgtatttttt
     1921 agatactctt catccaatac actcatctta cttttccgta aactctccgt ctacgacgtc
     1981 atcgcctgcg ttccctgttg cttgtgcgcc ttctgctcct tcttgagctt gttgcgctgc
     2041 tgcggcttgt tcgtagagtt taacagcaag tccttgagct ttttcgttca atgcttcaag
     2101 ttttgttttc atgtcgtcca agttgttgtc ttcttgagct ttcttaaggt catcaagggc
     2161 agcttgggca gcgtcacgtt ctgcgtcgaa gcctttacct tcagtttcct tgattgtctt
     2221 ttcagtcgca aagattgctt ggtctacttc attacgaagg tctacttctt ctttacgttt
     2281 cttatcggct tcagcgtttg cttctgcatc tttcatcatg cggtcgattt cttcgtcagt
     2341 caaacctgag ttcgattgga tgacaatagt ttgttctttt tgagttccaa ggtctttggc
     2401 cttaacagac acgataccgt tcttgtcgat gtcaaatgtt acttcgattt gaggaattcc
     2461 acgaggtgca gctgggatat cagtcaattg gaagcgtcca agagtcttgt tatctgctgc
     2521 cattgggcgt tcaccttgaa gaacgtggat atcaacggct ggttggttgt ctgctgctgt
     2581 tgagaagact tgtgatttag atgttgggat tgtagtgttg cgatcgataa gttttgtaaa
     2641 tactccaccc attgtttcga taccaagtga caatggcgtt acatcaagaa ggacaacgtc
     2701 cttgacatca ccagtaatca caccaccttg gatagccgca cccatagcaa ctacttcatc
     2761 agggtttact gatttgtttg gttctttacc agtttcagct ttaacagctt caacaacggc
     2821 agggatacga gttgaaccac caacaaggat aacttcgtcg atttctgaca agctcaaacc
     2881 tgcatctgaa agggcttgac gaactggaac ttttgtacgt tcaacaaggt cacgagtcaa
     2941 atcgtcaaat ttcgcacgag tcaaagtcat ttccaagtga agaggtccag cctcacctgc
     3001 agtgataaat ggcaagctga tttgtgttga agttacacca gaaaggtctt tcttcgcttt
     3061 ttcagccgca tctttcaaac gttgcattgc catcttgtca gtagacaagt cgataccgtt
     3121 ttctttcttg aattctgcta ccaagtggtc aatgattttt tggtcaaagt cgtcaccacc
     3181 aagtttgttg tcccctgcag ttgacaatac gtcgaagaca ccgtcaccca attcaaggat
     3241 agagacgtcg aatgtaccac caccaaggtc aaataccaag attttttctt ctttgtcagt
     3301 cttgtccaaa ccataagcaa gagctgctgc agttggttcg ttaacaatac gttctacttc
     3361 aagaccagca attttaccag cgtcttttgt tgcttgacgt tgagcgtcgt tgaagtaagc
     3421 cggaactgtg ataacagctt tggttacttt ctcaccaagg tagtcttcag cgtagccttt
     3481 caagtattga aggatcatag ctgagatttc ttgtggagtg tattcttttc catttgcaga
     3541 aactttttca gaagttccca tcttagattt gatagagata actgtatctg ggtttgtaac
     3601 tgcttgacgt tttgcagcat caccaacgat gatttctccg tttttgaatg agactacaga
     3661 tggagttgtg cggtttcctt ctgggtttgc gatgattttg ctttcagttc cttcaagaac
     3721 tgcaactgct gagtttgttg tacctaagtc aataccgata attttagaca tgtgtttttc
     3781 tccttgttag ttaattttct atttttcttt ttgatactct tcttaagtgg cgacgccgtc
     3841 agagcttgac ttcgtcagtc tcttttacta aactttgagc ctaaggtctc aaaatttgcg
     3901 caaatagcgc cacggcgaag agtatcgtct ttggttcgct tcgctcacta ttacaaagca
     3961 aaacatattt tatctttctt catagtttat tgtcgtttcg gacaagtttt ctattatgta
     4021 aattgcgaca cgaggagtcg aaatcgattt tatttcgacg acgagttagt aaggaagcta
     4081 ggcaaacgcc atagcaattg ccgttttctg acgagttgct ttagctaccg tcagaattgc
     4141 cgaatcgaac acgccctaag ctctgagtaa aaaagataga ttttcttgtg ttcatcgaac
     4201 acttcgtcaa tctcctattt ttactgcgag ctttttacgg gctttgtatc ttagttatac
     4261 accactacca ttgctgggcg taggatgcgg tcatggagtt tgtagccttt ttgaaagact
     4321 tgggcgatgg tatctactgg gtgttcatcg tctgctggga gagtttggat ggccatatgg
     4381 tagttatggt caaattcgcc atctgctgcg atttcttcaa ttccttcttc tttcaaagcg
     4441 tgaatcaagc tttcttgcac catccccaag cccttcttca catcatctgt caaaccttca
     4501 actgcaagtg cacgctcaag gttgtcaaga gatggtaaga ttgcttttgc caagtcctgg
     4561 ctacgataac gttgcaagtt ttgacgttct tcattggcac ggcgttggat attttgcatt
     4621 tctgcatgag cgcgaagata tttgttttcg aactcatctg cacgttcatt tgccaagtcc
     4681 aactcagact tttcaggagt tgtttcttca gctgtttcca caacttcctc ttcttgaact
     4741 tcttctactt cttcattttt tatatcttgg gccatgttcg cctcctttaa tgatttcaat
     4801 cttaatgtac ttcgtaatga ttactgctga ggtagcggta aaaatctgtc aacttcatgg
     4861 tcaaaacacg gttgaccaca ttgatttgat tgattagctg ttggtaatcc agattaactg
     4921 gaccgataat ggctagaatt ccaactcccc gataaggaat gaggaactta ctactaatca
     4981 ccgctaggtc agctaaacag gactcttgac cgtctgcaac acgaacattt tgcatctgat
     5041 cctcacgcaa cccctcacga atctccaagg ccaccttttg cggttggtca aagaactgat
     5101 aggctgctag attggcaaaa ttcaagagat tgaccttgcc cgccatcaca atgttttcgt
     5161 tgaacatttc cttaaagatg tgttcaaaga gatcgatgac attatccgtt gttgtaaagt
     5221 aacgctggat aatctgcgga atctccgtcc gaatcttgta gtgaatatct aaaacggtgt
     5281 gaccgaggaa acgttcctga atgatgctct tcagtttcag caaatcctcc tgcaagaagt
     5341 tccttggaat cagaaactga ctagtaaccg ttcgcgactc gtctagggta aataccgcca
     5401 aggctgtatg ttgccccaaa acaacgatat caaaggctgt caaacgttgc ctgctcggct
     5461 caacatccag tgccactacc gtacagccac tcaggtctgt tagcaagtta gcagcctctt
     5521 gcagaatatc ctccaatttg aagaattcct gatcaaaggc tttgacaatc tcatatacct
     5581 cattttcagc cagtcggtca aaatccagtg agtgtttcac atagtactga aaaccagcaa
     5641 cacttggcat ccgaccgctt gaagtatgag ccttctcaag caacccttgt ttttctagtt
     5701 ccgccatgtc attacgaatg gttgcactgc tagagttaat agactcttgc aaggcttttg
     5761 atccgacagg ttcgtgcgtt ttggtaaaga tgtcaataat cagatttaaa atatcctgct
     5821 gacgctctgt aaccatctca tcactcctct ctgtctgatc aattagcact caatgcatcc
     5881 aagtgctaac ttatgattct attatacacc cttagaagag aatgtcaaga caaaaactca
     5941 aaaaattagc actcttttat aaagagtgct aaaaatcaat ctgaagacct agaaccttgc
     6001 tattcatcta ctcggtattt cctttttagt ctgaaataac catgaattag ataagaaatc
     6061 agaaaagcat ataaaacaaa aataagaaag aaagacatag aaagatcctc tctaaacaaa
     6121 ctcatacaaa caacaagacc acctaagaaa gtagctatac aggaacgaag tctagatcgc
     6181 ataacttccc atttgagccc cttactcata tagacttgat cctctggaag taaatcagaa
     6241 gacgatttac gaagaatcga acaagaacct gctcctatca attcccaacc tctatctcta
     6301 aaatcttgca gttcacgctt atgctcttta agaaatctag aatcatagat acgatagata
     6361 acatcgtccg gttgaccttg ctcaaaatag aacaaaccaa aacgactagt tctatacctc
     6421 caacctttca aatgcatctc atgtaaatat tcttctttct tgtccaaatc aacaatggtg
     6481 aaaatccgaa attctactct gctattcatt gtcttacccc aaaattagaa aacatgccta
     6541 gcgttattta ttagataatt ctttccactt ttgactcaat ctccaaaaaa tataagaaat
     6601 ctgaatcgca aaaactatca ataaaaccca atctattatg aaaatcaaaa acacttccca
     6661 actgaaagaa ctacctccag tgacaaactt tgagaaaaac ggtagtagag ctaaaaagag
     6721 aagcaaaata ggaagcatcc gcattgttaa aatccttttg gcataaaaaa atctttattt
     6781 aaacgaaaat attatggcaa aatttacgcc agtttttgaa cggctgatgt agatatttta
     6841 tactttcaaa atgtttaaat gtgattattt atttttgaaa aatagctcac cagcccgact
     6901 gaaagtgctt atagaatgat aataagtcgc ctgccgaaaa cagcgaaaaa tagcagtgtt
     6961 atgcggagat aatctgacgc gatgcgaaag tatattgcat acttattttc aacaatttag
     7021 cagagtattt ttataagtgt gatataatag aagtataatt tgttctgata gtttatttta
     7081 tggagaagta gatttttaga atgcggagga ttcaatatgg ttgagtttat aaagtctaag
     7141 aaagaaatga gtgaggagga tattaaagca aatttcatca ctcctgctat tgtatccaaa
     7201 ggatggaaaa atggtgagca tatcgcttac gaagaatact tcactgatgg tcgaattgaa
     7261 gttagaggag ataaggctcg tcgtaaagaa ggaaaaaaat cagactattc actgtattac
     7321 caatttggaa ctcgaattgc aattgttgag gcaaaggata ataaacacag cgttcgagca
     7381 ggattacaac aagctattga atatggagag attttagatg ttccatttgt ttattcttcg
     7441 aatggtgatg gctttattga acacgaccgt atcacgagag aagaacgtga gctggagtta
     7501 gacgaattcc ctactcgtga agaattattt tctcgtatga cgaaggaaaa aggattgacg
     7561 tacgaaatta cagaagctat ctcaactcca tactatacag acgccttctc aatgaaaacg
     7621 ccacgctatt atcagcaaat agctatcaac cgtactattg aaacagttgc cagaggacaa
     7681 aaacgagtaa tgtttgtgat ggcaacagga acggggaaaa cgttcatggc ttttcaaatt
     7741 attcatcgcc ttcgaaaagc tggtttggct aaacgagttt tattcttagc ggatagaaac
     7801 atcttagtag accaaacgat ggctgaagac tttaagccat tcgaaaaggt aatgacgaaa
     7861 attacaccaa aacttttgac tgctcctgaa aaattaaatt cttttgaaat ttatctaggg
     7921 ctttatcagc aactaactgg tgaagatgga actgaaacac attatcaaaa atttgataaa
     7981 gacttctttg atttaatcgt aattgatgaa gcgcaccgtg gttcagctaa ggaaaacagt
     8041 aactggcgta agataattga ttatttcagt tctgcgacac agattgggat gaccgctact
     8101 cctaaagaaa ccaagaatgc ttccaatacg gaatactttg gtgagccaat ctatacttat
     8161 agtttaaaac agggaatcga ggatggtttt ttggctccat atcgtgttat gagggttaat
     8221 ttagatgtgg atgtggatgg ttatcgtcca gaaactggaa aagttgatac taacggacaa
     8281 ttaatagaag ataggtacta cggcaggaaa gattttgata aaaccattgt cattgatgat
     8341 agaacgcaaa gagttgccaa gtttgtttct gattatatga agcaaaacaa tgcacgattt
     8401 gataaaacaa ttgttttttg tgttgatatt gaccatgccg agcgaatgcg tgctgcactt
     8461 gtaaaagaga atctagactt agtccaagaa gactatcgtt atgtcatgca agtaactggt
     8521 gacaacgctg aaggaaaagc tcaactggat aactttatgg atgtcaattc taattttccc
     8581 gctatggtaa caacgtctaa attattaacg acaggagtta atgctaaaac atgtcgtttg
     8641 attgttttag actctaatat ccaatccata actgaattta aacaaattat tggtcgtggc
     8701 acacgtcttt atcctcaaaa ggggaaagaa ttttttacga ttattgattt tcgaaatgtt
     8761 accaatttgt ttgctgaccc tgattttgat ggtgagccag tgaaggtgct ggaaacaggt
     8821 gcgaaaacag tcagtggttc cacgcccggt ttcgtagatg aggaaggtga cccagtagaa
     8881 aaatatatcg ttacagacaa gcaggttacc attcttaatt ctactgttca agtattggat
     8941 gaaaacggga aactgattac cgaaagcctg accgactaca ctcggaagaa tatcttaggt
     9001 agctacgcca ctttgaacga ttttatcaca gtttggcata cggcgaataa aaagaagctt
     9061 atcttagacg aactttataa aaaaggagtt tatctagatg ctattcgaga gtcggaggga
     9121 atatcagaac aagaaatcga tgattttgat ttactcctaa aacttgccta tggtcaaaaa
     9181 gaattaacca aaacggaacg tatcaataaa ctcaaacaaa gcggatattt atataaatat
     9241 agtgaggaag cgcgtgctgt tttggaaatt ttactgaaca aatacatgga taaaggtatt
     9301 ggagaactcg aaagcattga aacattaaaa cttccagaat ttcagatata tggtggaacc
     9361 ttcaaaatca tcaatactta ttttggagat aaaaaacgat atttacaagc aattaaagaa
     9421 ttggagcaag agctatttac agtagcttaa tgaaaggaaa gtatgtcaat tacatcattt
     9481 gtaaaaagaa ttcaagatat cactcgaaac gatgctggtg ttaatggtga tgctcaacgt
     9541 attgagcaaa tgtcttggtt attattctta aaaatttatg atagccgtga aatggtttgg
     9601 gaattagaag aagacgagta tgagtcaatt atcccagagg aattaaaatg gcgaaattgg
     9661 gctcatgctc aaaatgggga acgggtattg acaggcgatg aattacttga ttttgtcaat
     9721 aacaagttat tcaaagagtt gaaagagctt gaaataactt caaatatgcc tattcgaaaa
     9781 acgattgtta aatcagcttt tgaagatgcg aacaactata tgaaaaatgg cgtcttgtta
     9841 cgccaagtca tcaatgttat tgatgaagtt gatttcaata gccctgaaga tcgtcattcg
     9901 tttaatgata tttacgaaaa aattcttaaa gatattcaaa atgctgggaa ctcaggagaa
     9961 ttttatacgc cacgtgcagc gactgatttt attgccgaag ttcttgaccc aaaacttgga
    10021 gaatcaatgg cagaccttgc ttgcggaaca ggaggcttct tgacttcgac tctgaaccgt
    10081 ttaagtagtc aacgtaaaac tagtgaagat accaaaaaat ataatacagc tgtttttggt
    10141 attgaaaaga aagcatttcc tcatctttta gcagttacaa atctgtttct tcacgaaatt
    10201 gatgacccta aaattgttca tggaaatact ttggagaaaa atgttcgtga atatacggat
    10261 gatgaaaaat ttgacattat tatgatgaat ccaccttttg gagggtcaga attagaaaca
    10321 ataaaaaata actttccagc agaattacgg agttctgaaa cagctgattt atttatggct
    10381 gtcattatgt atcgtttgaa agaaaatggt cgtgttggag ttattttacc tgatggtttt
    10441 ctatttggtg aaggtgtaaa aactcgcttg aaacaaaaac tggtagatga gttcaactta
    10501 catacgatta ttaggttgcc tcatagtgtc tttgcaccgt atacaggaat ccatacgaac
    10561 attcttttct ttgataaaac aaagaaaaca gaagaaactt ggttttatcg tttagatatg
    10621 ccagatggtt ataaaaattt ctcgaaaact aagccgatga agtcagaaca cttcaatcct
    10681 gttcgtgact ggtgggaaaa tcgtgaagag attctggaag gtaagttcta caaatctaaa
    10741 tcatttacac ctagtgaatt ggctgagttg aattataatt tagaccagtg tggctttcca
    10801 aaagaggaag aggaaatctt aaatcccttt gagttgattc agaattatca agcggaaaga
    10861 gcaactttaa atcataagat tgataatgta ttagctgata ttttgcagtt gttggaggac
    10921 aaataatgac accagaacaa cttaaagcaa gtattctcca aagagcgatg gaagggaaat
    10981 tagtgccgca aaatcccaat gacgaacctg caagtgaatt attaaagaga attaaagctg
    11041 aaaaagaaaa acttatcagt gaaggaaaaa tcaaacgaga taaaaaggaa actgagatat
    11101 ttcgtggtga tgatg
//
LOCUS       DBERPV010000048        10880 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.48, whole genome shotgun sequence.
ACCESSION   DBERPV010000048 DBERPV010000000
VERSION     DBERPV010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10880)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10880)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10880
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.48"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            268..588
                     /locus_tag="ACL8C7_001850"
                     /pseudo
     CDS             268..588
                     /locus_tag="ACL8C7_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884744.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            709..1653
                     /gene="manA"
                     /locus_tag="ACL8C7_001851"
     CDS             709..1653
                     /gene="manA"
                     /locus_tag="ACL8C7_001851"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HGS1395996.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKIGEYWAISAHP
                     NGVSKVANGRYEGTDLATLYVEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDDLLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTVKADDLRSTLLVSNDFFAVYKWEITGKVDFEKTADYSLLSVLAGQGQL
                     IVDGKNYPIQKGSHFILPSDVEAWTLEGQGLELIVSHP"
     gene            complement(1674..3152)
                     /locus_tag="ACL8C7_001852"
     CDS             complement(1674..3152)
                     /locus_tag="ACL8C7_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HGS1395997.1"
                     /translation="MVFLTDLRKHNRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSE
                     KSQWGSKLGFILASAGSVIGLGSVWKFPYMTAANGGGGFLLIFLISTILIGFPLLLAE
                     FALGRSAGVSAIKTFGKLGKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFG
                     KLFQLGGTGDYAQLFTSIISNPAIDLGAQAAFILLNIFIVSRGVQKGIERASKVMMPL
                     LFIIFVVIIGRSLSLPNAMEGVLYFLKPDFSKLTSAGLLYALGQSFFALSLGVTVMLT
                     YASYLDKKTNLVQSGISIVAMNISISIMAGLAIFQARSPFNIQSEGGSSLLFIVLPQL
                     FDKMPFGTIFYVLFLFATVTSSVVMLEINVGNITNQDNSKRAKWSVILGILTFVFGIP
                     SALSYGVMADVHIFGKTFFDAMDFLVSNLLMPFEALYLSLFTGYIFKKALAMEELHLD
                     ERAWKQGLFQVWLFLLRFFVSSFQSSSLWSSLPNLCNQKGLE"
     gene            3235..3975
                     /locus_tag="ACL8C7_001853"
     CDS             3235..3975
                     /locus_tag="ACL8C7_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGS1395998.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSETAQYTSDAIAAYVQTNAE"
     gene            complement(4004..4459)
                     /locus_tag="ACL8C7_001854"
     CDS             complement(4004..4459)
                     /locus_tag="ACL8C7_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HGS1395999.1"
                     /translation="MNRREAVEFVNMCMIKNGDKILVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4479..5654)
                     /locus_tag="ACL8C7_001855"
     CDS             complement(4479..5654)
                     /locus_tag="ACL8C7_001855"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGS1396000.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(5713..6558)
                     /locus_tag="ACL8C7_001856"
     CDS             complement(5713..6558)
                     /locus_tag="ACL8C7_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGS1396001.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            6683..7240
                     /locus_tag="ACL8C7_001857"
     CDS             6683..7240
                     /locus_tag="ACL8C7_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGS1396002.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7259..7726
                     /locus_tag="ACL8C7_001858"
     CDS             7259..7726
                     /locus_tag="ACL8C7_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HGS1396003.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7815..8444
                     /gene="upp"
                     /locus_tag="ACL8C7_001859"
     CDS             7815..8444
                     /gene="upp"
                     /locus_tag="ACL8C7_001859"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HGS1396004.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8618..9208
                     /gene="clpP"
                     /locus_tag="ACL8C7_001860"
     CDS             8618..9208
                     /gene="clpP"
                     /locus_tag="ACL8C7_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HGS1396005.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            9287..9535
                     /locus_tag="ACL8C7_001861"
     CDS             9287..9535
                     /locus_tag="ACL8C7_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HGS1396006.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9637..10797
                     /locus_tag="ACL8C7_001862"
     CDS             9637..10797
                     /locus_tag="ACL8C7_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS1396007.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVIDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKNNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKS"
BASE COUNT         3435 a         2150 c         2309 g         2986 t
ORIGIN      
        1 tctttataag atttgcccat cagacgaaat ataataaatt gaaactagaa tagtacacct
       61 ctacttctaa aacattgtta gaaatcgatt tgactgtcct gattgatttg tcctattctt
      121 gtttcatttt actatagaac gatttgaagg cgtttatgat atttagctgt acgagagtct
      181 tttaaaagtg ttttgatggt ttggatttct tctttagttg atttcatatc actattatat
      241 aatgcttttt gattttagtt tagtattatc gtagaaaatg gactcggtgc tatggataca
      301 ccggatgaga atggttatgt agcagataac tatcggatta cttacttaga ggcccacatc
      361 aaggccatgc gagatgccat ttaccaagac ggggttgact tgcttggtta tacgacttgg
      421 ggctgtatcg atccggtttc agctggcaca ggggaaatga ataagcgcta tggctttatc
      481 tatgtagatc gagataatgt aggaaacgga gctctcaaac gtagcaagaa gaagtccttc
      541 tattggtaca aggatgtcat tgatagcaat ggtgcaagca tcgggtagag cacatttgtt
      601 tactattttt ataaaatctt ctccctgctt tataagatgt aaaaaagagt tcaattcgaa
      661 ctcttttttt gctataatga ggggagaaaa atcagacagg agatcgacat gtcagaacca
      721 ttatttttac aatcagttat gcaagaaaaa atctggggtg gagccaagct acgtgatgag
      781 tttggctacg acatcccaag tgaaaaaatc ggagaatatt gggccatctc agcccatcca
      841 aatggagtct ctaaagttgc caatggtcgt tacgagggaa cagatcttgc tactttgtat
      901 gtggaacacc gtgaattatt tggcaatcgt ccagaacctg tatttccact tttgaccaag
      961 atcctcgatg ccaacgactg gctcagtgtc caagttcacc cagacgatgc ttatggactc
     1021 gagcatgaag gcgaactcgg aaaaacagaa tgctggtaca ttatcgcagc ggatgaaggt
     1081 tcagagatta tctacggtca caatgccaag tcaaaagaag aactccgcca gcaaatcgag
     1141 gacaagaact gggatgactt gttgaccaaa gtccctgtta aggctggaga tttcttctat
     1201 gtaccaagcg ggactatgca cgctatcggg gcgggtatct taatccttga aacccagcag
     1261 tctagcgata ccacctatcg cgtctatgac tttgaccgca aggatgacaa aggcaacttg
     1321 cgtgaacttc atcttgaaaa atccatcgat gtcttgaaca ttggtgagcc agcaaatagc
     1381 cgtcctgtaa ctgttaaagc agatgatttg cgttccactc tccttgtatc taatgatttc
     1441 ttcgcagttt acaagtggga aattactgga aaagttgact ttgaaaagac agctgactac
     1501 agcttattga gtgtcttagc tggtcaaggt cagctaattg ttgacgggaa aaattatcca
     1561 attcaaaaag gcagccactt tatcctacca agtgatgttg aagcttggac tctggaaggg
     1621 caaggtttgg aattgattgt tagccatcca taaaaagaaa gggcctgagt ttactactca
     1681 agtccttttt gattacataa attgggcaat gaagaccaca atgatgatga ttggaatgac
     1741 gaaacgaaga aacgaagaag gaagagccag acttggaaca gtccttgttt ccatgctctt
     1801 tcatcgagat ggagttcctc cattgcaaga gcctttttaa agatatagcc tgtaaaaagt
     1861 gaaaggtaga gagcttcaaa tggcatgagg agattggaaa ccaagaagtc catagcgtca
     1921 aagaaggtct taccaaaaat gtgaacatcc gccatgacac cgtaagatag ggctgaagga
     1981 atgccaaaga caaaggtcaa aattcctaaa ataacactcc atttggcacg tttgctgtta
     2041 tcctggttgg tgatattgcc cacattgatc tccagcatca cgacagaaga agtgacagtc
     2101 gcaaagagga agaggacgta gaaaatggtt ccaaaaggca tcttgtcaaa gagttgaggc
     2161 aagacgataa agagcaagct cgatccccct tcagactgga tattgaaggg ggaccgagct
     2221 tggaaaatgg ctagacctgc catgatggat atcgagatat tcatggctac gatggagatt
     2281 cctgactgga ctagattggt tttcttgtcc aagtaagaag cataggtcaa catgactgta
     2341 acccctagtg agagggcaaa gaaagattgt cccagagcat agaggagacc agcgctagtc
     2401 agttttgaaa agtctggttt gaggaagtaa agaacccctt ccatggcatt tggcaaactg
     2461 agagagcgac cgatgataac aacaaagatg ataaagagca ggggcatcat gactttcgaa
     2521 gctctttcaa tccctttttg aaccccacgt gatacaataa agatatttaa taagataaag
     2581 gctgcttgag ctcctaggtc aatggctgga tttgaaatga ttgaagtaaa taactgagca
     2641 taatcacccg ttccaccaag ttggaacaat ttcccaaact caatacctag atagactaga
     2701 atccatcctc cgataacact gtaaaaagat aagaggataa agagggcaaa ggcgccaatc
     2761 caaccgataa agttgtactt gttattcttg cccagttttc caaaggtttt gatagcggaa
     2821 acgccagcac tacggccaag ggcaaactca gccagcagga gagggaaacc gattaaaata
     2881 gtggaaatga gaaagattag taaaaagcct ccaccgccat tagcagcagt catgtaggga
     2941 aacttccaaa cggaaccaag cccgatgacc gagccagcag atgctagaat aaagccaagt
     3001 ttcgaccccc attgtgattt ttctgacata gttaaactct gatctccttt ttcaaaataa
     3061 gaaaaagcta cttgagttgt caaatagcct tctgtttgat tgatagactt gactatccta
     3121 ttatgttttc taaggtctgt caagaaaacc attttcaagt tttcacacct ttctcaaaaa
     3181 cgcttgactc tgacctaagg ggaggggtta tactatcatt gtaaggagga aatcatgtac
     3241 catataaaag aagctgcgca gctttcaggt gtctctgtca agaccctgca tcactatgac
     3301 aagataggac tcttggtccc cttaaagtcg gaaaacggct atcgaaccta tagtcaagag
     3361 gatttggaac gccttcaggt cattctttac tacaaatatc taggcttttc tttagagaaa
     3421 atagcagagc tgttaaagga agaaaggaca gatttattgc cccatttgac taggcagttg
     3481 gactatctaa ctcgcgaaag gcaacatctg gataccttga tttccacctt gcaaaaaact
     3541 attcaagaac aaaaaggaga aagaaaaatg accattgagg aaaaattcac gggatttagc
     3601 tatcaagaca atcaaaaata ccaccaagaa gcggtagaga aatatggtca agaagtcatg
     3661 ggacaagcgc tcgaacgcca aaaaggtcac gaagacgagg ctacggccgc ctttaaccaa
     3721 gtctttcaaa ctttggcaca aaatcttcaa gttggtttac ctgcaacagc aaccgaaaac
     3781 caagagcaag cagccaagct cttgcaagct attcgcactt atggatttga ctgctctatt
     3841 gaggtattcg gtcatatcgg taaaggttac gtctacaacc cagagtttaa ggaaaacatt
     3901 gacaagtttg gttctgaaac agcccagtac acgtcagatg ccattgcggc ttacgttcag
     3961 acaaatgcag aataaatagg ctaggaattt cctagcctat tttttatttc aaatcataaa
     4021 gccagtcgtc accgtttttg tagtaaaaga attcactgag atcttcttct agaaacacac
     4081 gaagcatatc agacatatca tcggttgcaa gttttagatg agaaagattt tcaaagtcct
     4141 cccaccaaac tttcccttcg tctgaagact ggagttcacc agtaaagtgt tctgtcttgt
     4201 aaaaaaggac gacataacga taatccttgt cgtcatacca gtttttgata ccacagagtt
     4261 ggggtttgga aatgatcaga ccagtttctt ctttcacttc acgaatgaca gcatcgacaa
     4321 aggattcgcc acgttcaaca tgaccaccag gaaaagtaat gccaggccag tcgggactaa
     4381 ctcggtcttg gaccaggatc ttatctccgt ttttaatcat acacatgtta acaaattcga
     4441 ctgcctctct tctgttcatt cttcacaacc tttaatcttt aatcataatg cagacttccc
     4501 gccacccagc cggtacagag ggcagaagtg atgttaaagc cacccgtgtg ggcattgata
     4561 tccataactt cgcctgcaaa gtggaggcca ggtaccagct tactttcaag ggttttagga
     4621 ttgatttcct tgagactgac tccacccttg gtaacaaagg actttgcaag ggacattttt
     4681 ccagttacag gaattttaag ttctttaatg gactggacaa gttgttctcg ttccttttca
     4741 gtcagctgtt tgactttttc aggatatcct tgtacaaaaa attcggccaa gcgttctggt
     4801 aacaaggttt ttaaagcgtt tttcaaggat ttttcccgat tttcttctag aaatgtaacc
     4861 aagtccttct cagaaagttg aggcaaaaca tcgagtgaga gaacctcccc acctttgaca
     4921 aagctagaca tgcgtagggc agcaggacct gacaaaccaa agtgggtaaa gagtaaatca
     4981 tgagtgatga catgcttacc ataacttagg gtcacatcgt ccagagaaat cccttgtaag
     5041 gctttatgtg gaaaatctgt taataaagga ctttcagcag cctcaagatc ggtgatggta
     5101 tgcttaaaat ggcgagcaat ctcgtgacca aaaccagtcg aaccagtcga aggataagac
     5161 ttaccacctg ttgtgacaat gagtttctca caagtgaagg tttgatccgc tgacttaagg
     5221 acaaactggt catctacttt tttaacagaa acgatttcta tttgagtagc aacttgacca
     5281 cctagttcag tgattttctt ttccaaagct tcgataatag tccgagactt gtcactggct
     5341 ggaaagacgc gtccgtggtc ttcgacctta agtttaacac cattttctgt aaaaaagttg
     5401 atgatgtcat gattatcgaa ctgggagaaa acactgtaaa gaaagcgtcc gtttccagga
     5461 attccagcta gcaggttgtc taagctacca ttgttggtca cattgcaacg tcccccacca
     5521 gtcccagcta atttttttcc aagtttccga tttttttcga tgaggagggt tttctgtcca
     5581 taaaagctac tggaaatcgt agccatcata ccagcaggtc ccccaccgat gacaatagta
     5641 tcaaaatgtt tcatagctct attgtaccac aaaaaaacaa gagatgatgg tcacctcttg
     5701 tcaagaatgc aattaatcaa tttcatagcc catcagcaaa ccgccctctt ctgcatagaa
     5761 actgcagaga ccagaggttg gtagaatttt aatatccgct tgtgggaagg tttcacggat
     5821 tcgctctgag agctgttgac aacatttttc gttattgcgt tgggccatga caatacggcc
     5881 accagcatat ccagctttta ctaactcatc ataggcagct tgaactgatt tctttgatcc
     5941 ccttgctttt tgtagcaatt cgagagttcc agtttcacta gcttttccga ccatacgaat
     6001 gttgagaagg ccaacgaccg taccgataag cttgctcaaa cggccgttct tcaccaagtt
     6061 atcgactttg gctaggacaa agagcaactt agttttttct tgataggcag tgatagcttc
     6121 aaccacttct tcaaaagaca agccctggtc aatcaagtca ttcaattttt ctacgagtag
     6181 gtcaacttca ccaccagcag ataaactatc aatcacatga atcttagtgt caggatggtc
     6241 ttccagataa atattctttg ctagttgagc actattgtga ctgccagaaa gggtacctgt
     6301 gatggttact aggaaaatgt ttttggcacc ttcaaatgct cgcaaatagt catctgggct
     6361 tggacaagcc gattttgaag cttctgcagt tgcatacatg gtttccatca tttggtcaat
     6421 atcgagactg gcgtcatcaa caaagacctg atcagctact tgaatggtta aggggacgct
     6481 tacaaaggtt gtgttaatag ctggtgttgg cagttgacga taatcacaac cagagtcagc
     6541 aataatcttc caagtcatag aaattctcca tctttgtcag ttatacattg acaaaggttc
     6601 tgtctttttt tacaattata tcatgaaaac ccttgaaaca aaagcatcat ccgtctgttg
     6661 tgacaagtag aaagaaaatg ttatgtctga acgtagaatc tctgaaaagt ctcttgaaaa
     6721 tctcagaaaa tcaaaccaag aatccaattt attaaccaga gaagccattg aaacagccct
     6781 cttgcaactc ttggaaaaaa aggaactgac caagattagt atttctgaat tggtcaaacg
     6841 tgcaggtgtt tcgcgtgcgg ccttttatcg caattatgac tccaaagagg aaattttaga
     6901 gagcgtcttt aaacgaactg tccacaatat tatggaacag ctgcatcatt acgatttaaa
     6961 gacagacctt tatttggttt gggttcacct tttccgggag gccagaaagg aagctagagt
     7021 aattcaattg gccttggatt accatctgga aaaaatcttt gtccaagcca tgcaggaatt
     7081 tctagaaaaa taccatggga aatcaaaagg tgtcagctct tatcttcatt ccttctggag
     7141 ctcagccatc gtctctgtcc ttctaaaatg gatcaaggat ggcatgaagg taccagctga
     7201 aaagattgca gatttaggtt taccattttt taaaaaatag agaaaaagga gaaaagagat
     7261 gactgaaaaa agactggcct gggatgagta ttttgcagcc caagccctac taattgcgaa
     7321 tcgttccact tgtaaacgtg ctaaagtggg cgcgattctg gtaaaagata ataaggttat
     7381 ttccactggt tacaatggtt cggtgtcagg gactgagcat tgtattgatc acgaatgttt
     7441 ggtcattgaa ggccactgtg ttcgcaccct tcacgctgag gtcaatgcta tccttcaagg
     7501 tgctgagcgt ggtgttccca aaggctttac agcctatgta acccattttc cttgtctcaa
     7561 ctgtacaaaa caattgcttc aggtcggctg caagcgtgtg gtttatatca accagtaccg
     7621 aatggacgac tacgcccaat acctttatca agaaaaaggg acagaattga cccatttacc
     7681 acttgagaca gtacagacag ctcttaaaga ggctgatcta atgtaaaaat tatcaaaaat
     7741 aaatggttta gaaagatttt taaaccgttt tttggtataa taagaagaat aaattgaaag
     7801 aaggaattcc aaaaatggga aaaattgaag ttattaatca cccactgatt caacacaaat
     7861 tgtcaatctt gcgtcgtaca gatacttcta caaaagcttt tcgtgagcta gtagatgaga
     7921 ttgcaatgtt gatggggtat gaagtacttc gtgatcttcc actagaagat gtggaaatcg
     7981 aaacaccaat tacaaaaaca gttcaaaaac aattggcagg taagaaattg gccatcgtcc
     8041 caatcttgcg tgcaggtatc gggatggttg atggtctctt gagcttggtt ccagctgcta
     8101 aagttggcca catcggtatg taccgtgatg aagaaacact tcaaccagtt gaatacttgg
     8161 tgaaattgcc tgaggacatt gaccaacgtc aaatttttgt agtagaccca atgttggcaa
     8221 caggtggctc agcaatcttg gctgttgatt ctcttaaaaa acgtggcgca tcaaatatca
     8281 aatttgtctg ccttgtatct gctccagagg gtgtaaaagc ccttcaagaa gctcatccag
     8341 atgtagaaat ctttacagca gccttggatg aacgtttgaa cgaacacggt tatatcgttc
     8401 caggtcttgg agatgctgga gaccgcttgt tcggtacaaa ataagatcga aaagaagaat
     8461 gacttggaaa agtatttcca gtcacgaaag gaggttgggt ttttgtttct gtctaatgaa
     8521 agcagagcaa aaatttgacc ttttttgacc aagatattat aatagtctta tcttcagtca
     8581 tttgaccaac aaaattaaaa ctcaaaagga gaaatgaatg attcctgtag ttattgaaca
     8641 aacaagccgt ggagaacgtt cttacgatat ttactcacgt cttctcaaag accgcatcat
     8701 tatgctgaca ggtccggttg aagacaatat ggctaactct gttattgccc aactgctttt
     8761 cttggatgcc caagatagta caaaagatat ttacctttat gtcaatacac caggtggttc
     8821 tgtttcagct ggtttggcaa tcgtagatac catgaacttt atcaaggcag atgtccaaac
     8881 cattgttatg ggaatggctg catctatggg aacagtcatc gcatcaagtg gagcaaaagg
     8941 caaacgtttc atgcttccaa atgctgaata catgattcac caaccaatgg gcggtacagg
     9001 tggtggtacc caacaaactg atatggctat cgctgcagaa cacttgctca aaactcgtaa
     9061 taccttggaa aaaatcttgg ctgaaaattc aggtcagtca atggaaaaag tccatgcaga
     9121 tgcagaacgt gataactgga tgagcgccca ggaaacactt gaatatggct ttattgatga
     9181 aattatggcc aacaattcat tgaactaatg atgatagaag gcaaactcga ctgggtttgc
     9241 tttttttggt ataataggga gagatttctt agaaagagga tttatcatgt ttgaaaaagt
     9301 caatcgctct ggcttgatta tctatcttta ctataatcgt gatgccaaaa aactgcagga
     9361 ttatggagat attacctatc attccaagaa acatcgttac ttacaactct atgttccaac
     9421 tcaagaagtg gagcaattgg tcggacgctt gagcaaggaa aaatttatta aaaaagttag
     9481 ggtttgtcat atccaagagt tggaaacacc ctttgtgggc aatctttatc gataggaaaa
     9541 cgttatcatc gaaaaagttc aaggaaaaca ttgacaattt tctgataatt cggtatattc
     9601 ttaacagact atttaagaaa taaggagaca aaaaagatga agaaaaaatt tgccctatcg
     9661 tttgtggcgc ttgcaagtgt agcacttctt gcagcctgtg gagaagtgaa gtctggagca
     9721 gtcaacactg ctggtaactc agtagaggaa aagacaatta aaatcgggtt taactttgaa
     9781 gaatcaggtt ctttagctgc atacggaaca gctgaacaaa aaggtgccca attggctgtt
     9841 gatgaaatca atgccgcagg tggtatcgat ggaaaacaaa tcgaagtaat cgataaagat
     9901 aataagtctg aaacagctga ggctgcttca gttacaacta accttgtaac ccaatctaaa
     9961 gtatcagcag tcgtaggacc tgcgacatct ggtgcgactg cagctgcggt agcgaacgct
    10021 acaaaagcag gtgttccatt gatctcacca agtgcgactc aagatggatt gactaaaggt
    10081 caagattacc tctttattgg aactttccaa gatagcttcc aaggaaaaat tatctcaaac
    10141 tatgtttctg aaaaattaaa tgctaagaaa gttgttcttt acactgacaa tgccagtgac
    10201 tatgctaaag ggattgccaa atctttccgc gagtcataca agggtgaaat cgttgcagat
    10261 gaaactttcg tagcaggtga cacagacttc caagcagccc ttacaaaaat gaaagggaaa
    10321 gactttgatg ctatcgttgt tcctggttac tataatgagg ctggtaagat tgtaaaccaa
    10381 gcgcgtggca tgggaattga caaaccaatc gttggtggtg atggattcaa cggtgaggag
    10441 tttgtacaac aagcaactgc tgaaaaagca tcaaacatct actttatctc aggcttctca
    10501 actactgtag aagtttcagc taaagctaaa gccttccttg acgcttaccg tgctaagtac
    10561 aatgaagagc cttcaacatt tgcagccttg gcttatgatt cagttcacct tgtagcaaac
    10621 gcagcaaaag gtgctaaaaa ttcaggtgaa atcaagaata accttgctaa aacaaaagat
    10681 tttgaaggtg taactggtca aacaagcttc gatgcagacc acaacacagt caaaactgct
    10741 tacatgatga ccatgaacaa tggtaaagtt gaagcagcag aagttgtaaa atcataatag
    10801 aaaaatgttg aaatagggaa tgagcctttg actcactccc tgtttcgata tttaatactc
    10861 ttcgaaaatc tcttcaaact
//
LOCUS       DBERPV010000049        10756 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.49, whole genome shotgun sequence.
ACCESSION   DBERPV010000049 DBERPV010000000
VERSION     DBERPV010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10756
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.49"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(117..1541)
                     /locus_tag="ACL8C7_001863"
     CDS             complement(117..1541)
                     /locus_tag="ACL8C7_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HGS1396008.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQKEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2086..4365)
                     /gene="pulA"
                     /locus_tag="ACL8C7_001864"
     CDS             complement(2086..4365)
                     /gene="pulA"
                     /locus_tag="ACL8C7_001864"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051060 - pullulanase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HGS1396009.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQTYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGYLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLLTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4477..6435)
                     /gene="ligA"
                     /locus_tag="ACL8C7_001865"
     CDS             complement(4477..6435)
                     /gene="ligA"
                     /locus_tag="ACL8C7_001865"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HGS1396010.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6528..7706)
                     /locus_tag="ACL8C7_001866"
     CDS             complement(6528..7706)
                     /locus_tag="ACL8C7_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGS1396011.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNLFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7786..8649)
                     /locus_tag="ACL8C7_001867"
     CDS             complement(7786..8649)
                     /locus_tag="ACL8C7_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HGS1396012.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAIHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8652..10553)
                     /locus_tag="ACL8C7_001868"
     CDS             complement(8652..10553)
                     /locus_tag="ACL8C7_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGS1396013.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENAAV
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
BASE COUNT         3229 a         2365 c         1914 g         3248 t
ORIGIN      
        1 tgtactattc tagtttcaat atactataat accaaaaagt tcgtattttt tctataattt
       61 ttattatttt atagcaaaaa aataaaacca ggaaaacaat ttcctgattt tacacgttat
      121 ttcacatcaa aaacaatgga tttgacattt gtcatcgctt caatgctata tttaatccct
      181 tgcactccag ctccagaacc tttgacacca aggaatggga aattatctgg accacgctgg
      241 gttttattat taatgtggac tgtacctact tcaagttttt cagcaatttc aaaggctttt
      301 ttgaaatcat ttgtaaagac tgatgattga aggccgaatt cagattcgtt ggcaaaggca
      361 atagcttcct ctacactagc cacacgaatg attggtaaaa caggaccaaa tggctcttcc
      421 catgccactt tcatatcttt tgtaacttgg tcaaaaagca ctggccagag aagattgccc
      481 tcacgtttga ttggtgtaag agcctgagcc tctttttctt gtgcatcctc aatcaagccc
      541 caaatgaagt cggctgaagc attgtcaata acaggtgtaa tatcagcatt gtcaaatgga
      601 tcaccaactg ttaatttaga aacttctttc tgaagcaaag tagctaattt atctgctaca
      661 ctttcgagaa caatgacacg tttaatggcc gtgcaacgtt gtcctgagta gctaaaggct
      721 cctgcaacaa tttgcttggc agcatgttcc aaatctgcat cttctagtac aagagctgca
      781 tctttcccac caagttccaa catgatagga cgcataccag ctaaacgacc aatacgttct
      841 ccaatagggg ttgaacctgt aaagttgatg aagttgactt ctttgtgctc aatgatataa
      901 tccccaattt ctgaaccacg acctgtaatg gtgttgaaaa cacctgccgg aatccctgct
      961 tcttcaaatg ctttagccaa caagagtcca gaaatggaac cttgtgttgg tggcttaaac
     1021 atgaccacat tccctgcaat caaggcaggt gcaattttag aagcagataa attaactgga
     1081 taattaaagg gagcaatcgc tagcacgata ccaactggtt cacgacggac aacagccagt
     1141 ttgtttttac ttgctgcctc aaaaccacca ccttccattg cttgtccagt gatacggaga
     1201 ccttcctcag cagcataacg aatcaagtct gctgtacgca ctacttctcc aattgctgct
     1261 ttaatccctt ttgctacttc tttggcaagg atagtaccaa ttttttcctt atcgcgttct
     1321 aaaatagctg ctgttttatg caaataagcc gcacgttcaa ttgctgataa agctcgccat
     1381 gctggcaggg ctgcacgcgc agcttgcata gcctcatcag cttcagtctg agtcatggct
     1441 ggaactgtac ccaattcttc ttgattgatt ggtgaataaa tcgtaatttc ttgttcagat
     1501 gatttccatt ttccatttac taaattctga tatcttgtca aattcttgtc ctcctgaaaa
     1561 tgattaagat atattttacc aaattttcag aaaatcacaa ccctttttgc aaaatttttg
     1621 agattatttt cacaagcttg atttttcaaa gtatactcaa taaaaataaa aaaaatccac
     1681 tacatcaagg cgagactaat gtggtttgaa gaaattttcg aagagcgtga atgagtatca
     1741 tctatagtaa aataaaaaaa ctgaacaatt tggttgggga cagtcaaacc aatttctcac
     1801 aatgtttcag aaacaagggt gtgctattcc aatttcaggc tactataact gtcatagatt
     1861 gctgaaacaa agtctaggta aaagtcttca taataaaaag accccctatc aagtgttcaa
     1921 aaactttgat aggaggtctt gttttgtgaa aatatttatc aaattttcta tacaagtgag
     1981 ctgttagcca ggttctttct attctttcaa tttcaatgaa tggatttttt accaatactc
     2041 ataactggga atttgtctgt gtaaaaatag cgagatagat ggtatttata aaacactcaa
     2101 gacagctaga ctaatatcat ttaaaacatt atcttctttt gagcgactgt tggttagcaa
     2161 catagctaaa tttcctgcat tttcaaattg atagggttct gatttagcat tcacaaccac
     2221 caagaggtgt tctttgccgt gaacttcata gataaggtag ccgctatgtt caatcgcaga
     2281 atgcacaaag acatgatggt aaatttcatc atagctagag taagaaaaag caccagtttt
     2341 tgtcttcaat cggatgactt gacggataaa ctcaatactg tcttgacgct cattaatcaa
     2401 gttccagttc acttggttca cactgtcagg agcattatag ctattcatcg cacgctctct
     2461 atcatcatgg gtcaactcac cattttcacc agtcgcaacc agtttggtac gaccaaattc
     2521 ttgaccgatt tccataaagg ccatcccctg catgagcaga ttcatggctg tggcagtttc
     2581 gaccttgcgc atgatttgct ctgaactttg gtctggatga agggttgcca ataaatcgtg
     2641 aagattgtaa ttgtcatggg cttctacata gttaagcacc tgatttggat gtgtatagct
     2701 tcctaattca cgacttccta ggattgcttt agctagaatt ggctctgtcg cagcaccact
     2761 gacaaaacct gacttgatag caccataaac ttctccccct ttgacagcat cgcgctgatt
     2821 gtcattaaag aaaccaatat ttggcatctg gtaggcattg tccttcttgg ccttatcata
     2881 aggggcaaga cctgttccca tatcccatcc ttctccatag aggataatgt tggagtcgat
     2941 ttcatccaag ctttgacgaa tcatctgcat ggtcttgaca tcatgaatcc ccatcaagtc
     3001 aaaacggaag ccgtcaatat tatattcctg cacccagtat agaagagaat caatcatata
     3061 cttgcgaaac atttcgtgtt cactggctgt ttcatttcca acacccgttc cattctggaa
     3121 ggtaccatct ggattcatac gataatagta atcagggact gttgtttgga atggtgcatc
     3181 aacaactgag aaggtatggt tatagactac atccataatg actccaatac ccgcatcgtg
     3241 ataagtttga accatcacct tcaaatcacg aatgacctga gctggatcat ctggattagt
     3301 tgaaaaacta gtttctggcg cgttatagtt ttgtggatca taaccccagt tgtaggttac
     3361 atttccatcc tcatcgtatt ctttatgacg gtctgcaatt ggttgcaatt gaacataatt
     3421 gtagcccagc ttcttgatgt aatcaaaagc agttgactgg ccgtattggt taactgttcc
     3481 agcctgagca gcacccaaga aagttcctcg aagatgttca tctacacccg atgtaggtga
     3541 tttagtcaaa tcacgaatgt gcatttcaca gataactgcc ttacatggat tttccaagcg
     3601 ccaagtagcc tccgaaccgt gcttaacctc gaagttttca acttgctttt ctacatggct
     3661 cagaatagct gaacgtttgc catcagggct ggtcgcgatt gtataaggat cacgtgtcag
     3721 tgtttggtga tgagggaatt ggacttgata ctgataagtc ttacctacca aatcttcttc
     3781 aacatccaaa ctccagacac cgattgtatt gtccttatga ttataagagt agctattgcc
     3841 tcttttcatc tcaaaagtct tccaaacggg tgcatcatta gcagctgatt cataaacgac
     3901 aacttgtact tctgtcgctg taggtgacca gagggaaaaa tgagcctgat tgtcctctac
     3961 acggcaaccc aattctcctt ggtaacccca atgatgatca aaactagcac tgttaatggc
     4021 cttatcaaag gcaaaaggat tttgattttt atagaaagga ctggcaatag caggattttc
     4081 agagtaataa atcctatcat cgccttccaa aatccagacc tctgttaata ggggatagtg
     4141 attaaaacgg atagaatatt ctttactagt ttgacctgta tgaaccacaa aattcaagct
     4201 ttctataaca tgtgaacttg ggtgttcaaa gctaaataaa gctccaaaat aatcttcttt
     4261 gtaggttagc aaatcaattc gttgatcctg actttttaca aaggagcaag tgtcatattc
     4321 tccattctta cgatggtaat gaatgcgcat agggtagtta tacatttttt atttttcctt
     4381 tttactttgt ttctatttca ctaataaatt tttgtcaatc tcgtctcaat taacagacat
     4441 agtcatattc tctaaactct gtttttaaac gatccattac aaactttcta gccatgcctc
     4501 atctctgacc tggataccaa gttcttgtgc tttttgcagt ttacttccag cgtctgcacc
     4561 taccacgacg aggtcggtct ttttagaaac actacctgtc actttggcac ccagactttc
     4621 gagtttactt ttagcttctg agcgcttgag tcgttccaat tttcctgtca ataccacggt
     4681 caaacctgac aaggccgcat ccgctactac cgtctgtcct ttatagtcca gattgacccc
     4741 agtttctttc aattctctga gcagaatttc agagccttct gtcgcaaaat aagtctgaag
     4801 acttttggca atcacgccac ctagactttc aatactagcc acttcctctg aatctgcctg
     4861 atacagattt tcaattgaat gaaaatattg aagtaaaagc tgactagcct tgcttccgac
     4921 atgacgaatt cccaaaccaa ataagagctt ctcggcagaa ttttcctttg atgcttggat
     4981 agcctgatac agtttagcag cggacttttc cttaaccccc tctaaaagga ggaaatcctc
     5041 ttcttgcaaa cgataaatat ccgccacatc cttgactaaa ttagcagcaa aaagcttctc
     5101 aacaatagat ggaccaaggc ctgtaatatt catagcatca cgagaagcaa agtgaatcaa
     5161 gccttccatg atttgagcag ggcaacgcgg attgatacaa cgtagggcca cttcatcttc
     5221 aaagtgcaac aagtcagagt tacaacttgg acagtttgta gggatatcta gtttttcttc
     5281 agaaacccgt ttggactcta ccacacgtaa aacggcaggg atgatgtcac cagccttata
     5341 tacaatgacc gtatcgtctt ttcggatatc tttttcagca atataatcta cattgtgcag
     5401 ggtcgcacgg ctaacagtcg taccggcaag ttgtactggt gttagattag cagttggagt
     5461 tacaacaccg gtacggccaa ctgtccagtc aactgataag agttgagctt ctttttcttc
     5521 ggcagggaac ttgtaggcta ctgcccactt tggagcctta actgtaaaac caagttcttc
     5581 ttgacttgct aggtcgttga ccttgattac cactccatca atatcgtaag gcagattttc
     5641 ccgttcctgt cctacttctt ggataaaatt ccagatttca tctatgtttt cagccaagat
     5701 tcgcttagga ttgaccacaa aacctagttg ttctaggtac ttcaaaccct tttcttggct
     5761 atcacgagtt gaagggctgg cttcttgata gagaaacgtt gcaagattac gcttggcaac
     5821 tactgctgta tccaactgac gcagagttcc tgctgccgca ttacgaggat tagcaaattc
     5881 aggctctcca ttttcttggc gcacttggtt aacttggtca aaggaagcgc gtggcatgta
     5941 acattcccca cgaactgtga tatctagttc ttctggcaaa gtcaaaggga tgtccttaac
     6001 acgcttgagg ttttctgtga tattttcacc aattgaacca tctccacgtg ttaccccagc
     6061 aaccaaaatc cccttttcat aagtcagcga gatagataag ccatcgattt tcagctcaca
     6121 aatataggtc ggatgagcca cttccttacg aacacgcgca tcaaaagcat ctagctcctc
     6181 acgtgaaaaa gcatcctgca aactataaag aggatactga tgactgtatt tttcaaaacc
     6241 atctaaaacc ttgccaccaa cacgatgagt cggactgtct gctagcactt gctctggata
     6301 agcagtttct aactcgacca actcacggta aaggcggtca tactcactgt ctgaaaccga
     6361 gggattatcg ctggtatagt actcagtcgc atagcgattg agcaaagcga ctaactcatt
     6421 cattctttta ttcataagac cattttacca taaaacaagc cctcctcaca aacgagaagg
     6481 acggaaaaaa cacttagttt gaaattattt ttgaaactca agcaacctta tatcaatttt
     6541 tcaaaatgag ttcgaacata aataaacgat atacaagaca agatgataac accacttcca
     6601 attatcagga aagaagagag atgtacactt ggcaagactg tcataaatcc ttttgcaata
     6661 ggcataaata gaatagctaa ggtaaaaatt gtactcagta ctctcccaag aaattcgctc
     6721 tcaaccttgg tttgtacttg agtaaaaaag tgaatattaa aaatcgtcat aaacaattca
     6781 caaactaaat ttccagaaaa ggaaagaaaa gttggaagtg gtaatcccat cataaaaact
     6841 ccgacacctg tcaaagccag taaaatcaaa agattataaa tattagcttt aattttacta
     6901 gctagaagag ccccaatgat ggaaccaata gcccccatag ttaaaatact tgcataggct
     6961 ccttctgacc cgtaaagctg attcgaaaag ggaagtagaa attcaaaagc tgcaaaaaag
     7021 aaattaacgc tggaagctac cagcaaaagg aagaaaattt cttgctgatg ccagatatag
     7081 tgtaacccat ccttgatatc tacaaaaata tctctcccag taaaagcctt tttctcttga
     7141 acttttgctt cctcttttgg aaggaaagcc actagaacaa aagcaatgaa aaaagtcagc
     7201 gagtctagca gtagcgtcat atggagactt gcaaactgta aaacaaggaa ggaaagaaca
     7261 ggagagctaa cacctacaac ctgcaaaacc agctctaggc gagaattata gatcacaatc
     7321 tcatctttct ccaccacttc agttatgata gctttattgg ctgtgcgaga aaaggcaaaa
     7381 gcaatagcct gcacaatgtt agcaacaatc aaagcgccaa tcatccagct atcattcctt
     7441 atgaaagaaa tagccagaca aagaatccca caaacaagat ctgccgtcat taaaatctta
     7501 cgacgagaaa aacggtctga aataactccg ccaaagagat tgacgagaat agatgtgacg
     7561 agctcagaaa tctgatacat tcctaaaact gtctgtccta tagtccccat agaagccaac
     7621 cagacactat ttccataatc atagagcata tttcccattt tattgatagc cccacggcta
     7681 atcaactgca ctgcatagcg attcatatta aagctcctct caaattttga aactattgta
     7741 tcaaaaccga aaggagattt ttattttttc ccttatttgg gaaaattaac ttttgacaaa
     7801 tttttcgtag tgttcctgat aataggctac ttgctctgga agacctaaca catcaaaaat
     7861 atgtatggcc tcttgcatct gcttacagcc ttctttacac tgtccttttt gatataaggc
     7921 aaaacctttt aaataatgga aaacattacg ctcataaagc ttaatacctt tgtcaataat
     7981 cttctctgta taagcctcaa aatagttggc attataaaaa gaagaatgct ctaaacaatg
     8041 ctggtaacaa ttgagggcca aaatcaaaac taatctctta tggcgactaa tctcttggta
     8101 aaattcctcc ctctccataa cttctctacc aatccgagtg acatagtcta catcgtagaa
     8161 actatagagg ttaccgaaaa gaatcaactc atacatggtc cattcttctg ttttgaagag
     8221 ataatctgct accttatcca aatcatcctg cttcatatca taactcgcat ctctttgaca
     8281 aatcagacct tgtagcaaaa tccagttcag ctcaaaataa aggggagtcg tcgaactctt
     8341 agacttttca agttgttctc tttgaagctt ttgaaaacct gcaatatcgt ttgaatagta
     8401 aagtgggata atctgtgcca tcatagacac atgttcatga ttatgaaaat tccttgcctt
     8461 atccatgaaa ttttcgattg ttacatgaat gttatccaaa atctcaaaga aacgggagac
     8521 tgccaggtca gactccccaa gctcaaagcg agataactga gaggtagagc aggattcgcc
     8581 tgctgcttcc tttaaagaat aatttccact tgttcgaaat tcacgaaata cttttccaag
     8641 atgttccatc tttacacctg atctgataat tcttcccact caagcatagc ttcttcctga
     8701 cgatggctga ttttgtccag ctcagcctgt aattccatga gtttgtcggc atcgtttgtt
     8761 tccaacattt gttcagaaat ggcttggctt tgactttcta gctcttcaat ttcagcttct
     8821 agactttcga tttgtcgcat gagtttgcga acttcttttt gactttcttt ctgggcctga
     8881 tagtcattga ctggacttgc ttcctttgct tgattgctag ttgaagcttc ctcagtctga
     8941 ctcatttctg ctgttgcttt cttctcaaca tagtagtcgt aatctccaag gtagagagtt
     9001 gaaccattct cagacaattc caaaacatga gttgccacac gattgataaa gtaacgatca
     9061 tgactgacaa aaagcaaggt accatcaaag tcaatcaaag cattttccaa cacttccttg
     9121 ctatcaatat ccaagtggtt ggtcggctcg tcaaggatca ggaagttgtt gttttccata
     9181 gacaatttag ctaaaagcaa acgagctttt tcgccaccag atagcatgcc gactgatttt
     9241 ttaacatcat ctcctgagaa aaggaaggct ccaagacggt tgcggatttc aacttctggt
     9301 gtcagtttga aatcattcca gagttcatcc agcaccgtat tacttggtgt cagcttgctt
     9361 tgggtttggt catagtaacc aacctcaaca ttagcgccaa agcgcttttc acctttgata
     9421 aaaggaatct ggtccacaat agacttgata aaggttgact tgccgatacc atttggacca
     9481 acgatagcga cagcattcat cttacgaaga tctaggttaa tcggttgtga caagacttcc
     9541 ccgtcatagc caacagctgc attttcaaca gtcaaaacaa cattgcccga cgttttttca
     9601 gactggaagg tcatgttggc tgctttcttg ccagcttcag gcttgtccaa acgctccatt
     9661 ttttctagtt gtttacggcg agattgagca cgtttagtcg ttgaagcacg aactagattg
     9721 cgattgacaa agtcttccag agcagcgatt tccttctgtt gcttttcata gttttttgcc
     9781 tcagtagcta gcttttgctc cttcaattcg acaaaacgag agtaattccc cacatagcga
     9841 tccaaggaat gcttggtcaa atctagcgta attgtcgcaa ccttgtccaa gaaataacgg
     9901 tcgtggctga cgataatgag ggcaccgcta tagtttacca agtaattctc tagccaggcg
     9961 atggtttcaa tatccaagtg gttagttggc tcgtccaaga ccaagagatt gggcttttca
    10021 aggagcattt tggcaagtgc caaacgagta ttttgaccac cagaaagctc agcaattttc
    10081 atctgccaca tagactcgtc aaacttgaat ccattcaaaa tcgctcgaat atcagcttca
    10141 taggtaaagc cacctgcttg gcgaaaattc tcagataagc ggtcataatc tgacatcagt
    10201 ttatccaaat cctcaccaga cttttcaccc atctccagct ccatctgacg cagttgtctc
    10261 tccgtccgac gcaaatcatt aaagacatga agcatttcat cgtagatggt attttcagac
    10321 tcaaaacggc tatcttgggc taggtaagac agagaaatat cttttttctt attgatttct
    10381 ccgctagttg gctcctcttc tccaactaaa atcttcaaaa gagtagactt acctgcacca
    10441 tttttcccaa caagagcaat ccgatctcgt tcatcaacct gcaggttgat attatcgaaa
    10501 agaacctctc ctgcaaaaga acgttcaatt ttattagctt gtaaaataat catacaagta
    10561 gtatagcatg tttccctaag tcattcaaga taatcgtaag tcttttagta caacttttat
    10621 aacataaaat aaactaaatt atgtatattt tatattagat tccttcacta tcttgttgga
    10681 ttttctaacc agctaatctt gtttcaaata gttatcgcac aagtctatta tttaattctt
    10741 ttcattattt acgtac
//
LOCUS       DBERPV010000050        10150 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.50, whole genome shotgun sequence.
ACCESSION   DBERPV010000050 DBERPV010000000
VERSION     DBERPV010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10150)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10150)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10150
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.50"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..364
                     /locus_tag="ACL8C7_001869"
     CDS             <1..364
                     /locus_tag="ACL8C7_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGS1396014.1"
                     /translation="VLVSIDYINCLSETTDKNWHKSDRVFVTNTGKTVHSSILSKSLQ
                     RANERLKKPIPKHLSPHIFRHTTISILSENKIPLKTITDRVGHSDSEVTTSIYTHVTK
                     NMKDEAINVLDKVMKKIF"
     gene            complement(502..1806)
                     /gene="eno"
                     /locus_tag="ACL8C7_001870"
     CDS             complement(502..1806)
                     /gene="eno"
                     /locus_tag="ACL8C7_001870"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface-displayed alpha-enolase"
                     /protein_id="HGS1396015.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            1970..2416
                     /locus_tag="ACL8C7_001871"
     CDS             1970..2416
                     /locus_tag="ACL8C7_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HGS1396016.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAKPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(2413..3528)
                     /locus_tag="ACL8C7_001872"
     CDS             complement(2413..3528)
                     /locus_tag="ACL8C7_001872"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0031388 - organic acid phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HGS1396017.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFNKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(3537..3866)
                     /locus_tag="ACL8C7_001873"
     CDS             complement(3537..3866)
                     /locus_tag="ACL8C7_001873"
                     /inference="COORDINATES: protein motif:HMM:NF019887.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HGS1396018.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(3811..4182)
                     /locus_tag="ACL8C7_001874"
     CDS             complement(3811..4182)
                     /locus_tag="ACL8C7_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HGS1396019.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLRREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4241..5674)
                     /gene="glgA"
                     /locus_tag="ACL8C7_001875"
     CDS             complement(4241..5674)
                     /gene="glgA"
                     /locus_tag="ACL8C7_001875"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004373 - glycogen (starch) synthase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HGS1396020.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKTKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(5671..6810)
                     /gene="glgD"
                     /locus_tag="ACL8C7_001876"
     CDS             complement(5671..6810)
                     /gene="glgD"
                     /locus_tag="ACL8C7_001876"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HGS1396021.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPKK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(6800..7942)
                     /locus_tag="ACL8C7_001877"
     CDS             complement(6800..7942)
                     /locus_tag="ACL8C7_001877"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HGS1396022.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(7932..9860)
                     /gene="glgB"
                     /locus_tag="ACL8C7_001878"
     CDS             complement(7932..9860)
                     /gene="glgB"
                     /locus_tag="ACL8C7_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003844 - 1,4-alpha-glucan branching
                     enzyme activity [Evidence IEA];
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0043169 - cation binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HGS1396023.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGYIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVAFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3082 a         2236 c         1788 g         3044 t
ORIGIN      
        1 tgttcttgtt tcaattgact atataaattg tctaagcgaa acaaccgata agaattggca
       61 caaaagcgac cgtgtttttg ttaccaatac aggaaaaaca gttcatagtt ctatcttgag
      121 caagtctctc cagcgagcaa acgaacgcct taaaaaacca attcccaaac atctgtcccc
      181 tcacatcttc agacacacca ctattagcat cttatcagaa aataaaattc ctttaaaaac
      241 aatcacggac agggttggtc attccgactc tgaagtcact acttccatct acacccacgt
      301 cacaaagaac atgaaagatg aagcaatcaa tgtactggat aaagttatga aaaagatttt
      361 ttaaaaagtt ttgccccttt tttgtcctct aaatacaaaa atagcccttc ggataaaatc
      421 cgaggggcta gaaacgttgt taaatcaacg gccgaacttt tgaatttcat ggttcgggat
      481 aaaatagttc actgaactat tttatttttt aaggttgtag aatgatttca atccacgata
      541 ttcagctact tcaccaagtt ggtcttcgat acgaagcaat tggttgtatt tagcgatgcg
      601 gtctgtacgt gaaagtgaac cagtcttgat ttgtcctgcg ttagttgcaa ctgcaatatc
      661 agcgattgtt gaatcttcag tttcacctga acggtgtgat acaacagcag tgtaaccagc
      721 ttctttagcc atttcgatag cttcaaaagt ttcagtaaga gtaccgattt ggttaacttt
      781 gataaggatt gagttagcag caccttcttg gataccacgt gcaaggtagt cagtgtttgt
      841 tacgaagaag tcgtcaccaa caagttgtac tttcttacca agacgttcag taagagcttt
      901 ccaaccatcc cagtcgtttt catccatacc atcttcaata gtgatgattg ggtatttgtt
      961 aaccaattct tcaaggtagt cgatttgttc tgcagatgta cgaacagcag caccttcacc
     1021 ttcaaattta gtgtagtcgt aaactttacg ttctttatcg tagaattctg atgaagcaca
     1081 gtcaaatccg ataaatacgt ctttacctgg tacatatcca gcagcttcaa tcgcagcaag
     1141 gatagtttca acaccatctt cagttccttc gaaacgagga gcgaatccac cttcgtcacc
     1201 tacggcagtt tccaaaccac gtgatttaag gattttctta agagcgtgga agatttcagc
     1261 accgtaacga agggcttctt taaatgttgg cgcaccaact ggcaagatca tgaactcttg
     1321 gaaagcgatt ggagcgtcag agtgagaacc accgttgatg atgttcatca ttggagttgg
     1381 aagaacttta gtgttgaatc caccaaggta gctgtaaagt gggatttcaa ggtagtcagc
     1441 agcagcacga gctacagcga tagacacacc gaggattgca ttcgcaccca atttaccttt
     1501 gttaggagta ccgtcaagtg cgatcatagc acggtcaata gcttgttgat cacgtacatc
     1561 gtagccaatg atagcttcag caatgatgtt gtttacgttg tcaacagctt tttgtgtacc
     1621 aagaccaccg taacgagatt tgtcaccgtc gcgaagttca actgcttcgt gttcaccagt
     1681 agaagctcct gatggaacca taccacgtcc gaaagcacct gattcagtgt aaacttctac
     1741 ttcaagtgtt gggttaccgc gtgagtctag gacttcgcga gcgtaaacat cagtaataat
     1801 tgacattttt tactctcctt atgagttaaa ttttttacac ctctataata ccttaaaacc
     1861 cctccttttt caagaaaaaa cgttatcttt gtgcaacttt tccttaactt tataaagtaa
     1921 tcgctttctt ttgtctgttt tattctaact tttatgatat actgttttca tgacagattt
     1981 atcaaaacaa ttacttgaaa aagctcatgg tgggttaaaa ataaatccgg atgagcaaag
     2041 acgctatctt ggtacttttg aggaaagagt tcttggatat gtagatattg acacagcaaa
     2101 tagccctcag ttagaaaaag gctttttatt tattttagaa aaccttcagg aaaaagcaaa
     2161 gccactattt gtgaagattt caccaactat cgaatttgat aagcaagttt tctacttaaa
     2221 agaagcaaaa gaaactgata gtcaagccac catagtatct gaagagcata ttacttctcc
     2281 ttttggcctg gttattcata gcaatgcacc agttcaagta gaagaaaaag accttcgact
     2341 tgcttttcca aaactttggg aagttaaaaa ggaagaacca gccaaaacat ccttatggaa
     2401 gaaatggttt agctaaatct tgcacatatt taataagtgc ccaatattgg cagccgtgcg
     2461 ctccagatag agactggcat ttttcaaact atcttctaaa ggttcacttt tctccaaaat
     2521 agaaaagaca gcttggatat tttcaaatgg taggggaggt aaatcttcag caagactacc
     2581 gcaaatagca ataacaggaa ctccaacagg ggttcttttt gcaacaccta taggcgcttt
     2641 cccagcaaag ctttgactat caagccttcc ttctccaaca acaaccaagt cagcatctga
     2701 aactttctta ttaaagttga ttaagtccaa gcaggtatca attccagaca cgatacttgc
     2761 ctgagcaaag gcacacaaac caccagcaag gcctccacct gctcctgctc ctttaatttc
     2821 taatgttgca ggtgagaatt tttcataaaa atcttggatc gcctgatcta cgactgcaaa
     2881 catagtcgga tgtagacctt tttgattgcc aaaagtgtaa gtcgcacctt gatgaccaca
     2941 taagggactc acgacatctg ctagaatatg aatttgaaca ccttcaggaa ttttatagca
     3001 attttctgtt gaaacagaag ctaagtttaa taaggattga ccggaagcag gcaagacatt
     3061 tccatcccta tcataaaatt gataacctaa accagcagca atccccagtc ctccatcatt
     3121 actggccgtg ccaccaacac cgatataaat atctttaatc cctttagaaa tgagatggag
     3181 aatcaactct ccaataccac aagtttggat ttgaagtgga tttcgtttct ctagcggaat
     3241 ttttccaaga ccaaccaagt cagctacttc aaatagtgcc agttcccctt tttgaaaata
     3301 gcgcatggct tctttttgtc caaaagggtc tgtcacttgg atccattttt cttttaggtc
     3361 aagagaatgt cggatagcat ctacagtacc ttctccccca tcaccaacag ggcagaggag
     3421 acattctaca tctgctatcg attgttggaa gcctcttttt attgcttcag ctacctgttg
     3481 agctgtcaag ctttccttaa acgaatccgg tgcaattaca atcttcatat tttccctcat
     3541 tctaaacagt caatcaaagg aagaacttct aaaaaatccc tcttgtcaac atgatgtggt
     3601 atttcttttt tgagcatttc tttggaacaa aaggcgattc ctaactccgc cgacttcaac
     3661 attaatagat tattgacccc atcaccgatt gccaccgttc tttctttaga aagttttagt
     3721 ttctttctcc atttttccag agtttctttt ttgacctggg gacttataat ttgtccaact
     3781 aattttcctg ttaaaagacc ttctttgact tcaagctggt tggcagtgaa ataggcaata
     3841 ccaagggatt ttgctaatct ctccaactat tggtgtaaat ccaccagaca ccagaccaac
     3901 taggatgcca ttcttttgga gaatagagat gaactctggg acatttagcg atagatgaat
     3961 tgagttgaag acgttatcaa agaccaaaat aggaagacct tccaacaagg acactctttt
     4021 tcttaaactg ctttcaaaga ccaactctcc tcgcatcgct cgacttgtaa tctgcgaaat
     4081 ttccgcctca tgacctgcct ctctccttaa aagatcaatc acttcttcta ggattaaggt
     4141 tccatctaca tccaaaacac acaagccttt tacttgagac atcagttctc ctctctaaac
     4201 agcctaaaaa tcgtatgaag tcatcatacg attttatcta ttaattaact aaactatggt
     4261 acaagtcaag gtatgacttg caggctgtat cccatgagaa gtcactctcc atagcttgtt
     4321 tttgtaggtt tctccaaatg tctggatggt ttctatacaa gtccaatgct gtttggaaag
     4381 tccaatttaa ccaataagga gatagattgt caaagctaaa gccagtaccg cttccttcga
     4441 ttggattgaa agcgcgaact gtatctcgca agcctccaac ttcatggacc aatggcaagg
     4501 ttccataacg catagccatc atttgagaca agccacacgg ttcaaaacga cttggcatga
     4561 ggaagaggtc acaagcagcg tagatttcct gagcaagttt gacatcaaaa gtgatatttg
     4621 ttgatagctt gtctgggtaa atctgagcaa accatgagaa agctccttca aaggctggat
     4681 cgccagttcc caaaagaaca atctgaacat cttcttgcaa gatatggtga agactttcga
     4741 ccaccacatc aaaacctttt tgacgtgtca aacgagaaac aattcccacc agtggaacgt
     4801 ctgctctaac aggcaagcca actctttctt gcaattttgt cttatttttg gctttcccag
     4861 acaaatcttc ctgattgaaa tgatagtcta aaagagcatc cgtctgagga ttataaagat
     4921 cagcatcaat cccattcacg ataccagata ctttaccaga ctccatttta agaatctgat
     4981 ccaaattaca tccaaactga ctagtcataa tttcatgagc atagctaggt gaaacggttg
     5041 aaacacggtt cgcatagaga atacctgcct tcatccagtt cagacagttg ttccatcgaa
     5101 gggtgccatc agcgtaacgt tcaaagccaa ctccaaacaa atcacccaac attccttctg
     5161 aaaattgtcc ttggaattct aaattatgaa tggttaaaac tgtttcaatg tcctcatagg
     5221 cttgaatcca acggtatttt tccttcaaca agaaaggaat catagctgta tggtagtcat
     5281 gaacatggag aagatcagga ataaagtcaa tcctttccat agcctcaatg gcagccagtt
     5341 ggaaaaaggc aaagcgttct ccgtcatcaa aatcaccgta aacatgacca cggaagaaat
     5401 aatattgatt gtcaataaag tagaaggtta caccatttaa tactgttttc ttaattccac
     5461 aatactgtct gcgccaacca acgctcacct caaaatgaag cacatcttca atctgatttc
     5521 caaatttagc ctctaccata tcatagtagg gtaaaatcac tgcaacttcg tgcccagctt
     5581 ttaccagtga ttttggaaga gcgccaatga cgtctcccaa accacctgtt tttgaaaagg
     5641 gtgcaccctc tgctgctaca aataaaattt tcatgaatga atatcctctg ttactttagc
     5701 acctttctta accacaactg gatgttctgc agttcctcga atcacaacac caggctcaac
     5761 ttcaacccct ttgtccaaga tagcatattc gacctgagcc ccttctccaa taacaacacg
     5821 agggaagagc aggctatctt taaccaagct atccttatgg acatgaatat tacgtgatag
     5881 aacagaatta gctacttgac cttcaataat actaccagag gcaaactgag aagtgcttac
     5941 cttagatgta ttagcatagt aagttggctc ttcgtttttg acctttgtat aaatcttttg
     6001 gtttggtgag aaaagagaat agaatttttg tgattcaagc atatcgatat tcgcttgata
     6061 ataagattta acagagtgaa tattggctag atagcccgtg tactcgtagg cgaaagctcc
     6121 ctcttttaca gccaaatccc gtaaaacata gcgcaatttc tttggatgtt cttttttagc
     6181 ttcttcttcc aagtgttcaa tcaaccaagg tgtatcaacg acaaagatat ctgtagacat
     6241 attgaacgtt tcagctgttg acttgctatc aaagagttta tgagaaagaa catggtctgt
     6301 ttcatctaca tccaagattg catttacttc tgaaatatct ttcttagcta gttttttata
     6361 aactacagtg ataggctctt ttgttgtact atgtaggtgg aaaacttggt tcaaatcaat
     6421 gttaataaga acatcgcagt tgagggcaac cgtttggttt gagccagaac gtttcaaata
     6481 agtaagaagc tgttggtagt attcttttcc aactgtacta ctttctacac gggtattgta
     6541 aattcctaga tagtaatgac taagaagggt tgataagccc cactcgcgtc ctgaacgaat
     6601 atggtcaaat actgagctga tattatcctg ctggaaaata ccaaagacac tacgaacacc
     6661 tgcattagca aggcttgaaa gtgggaagtc aatcaaacga tatttcccac caaatggcaa
     6721 acttgctact ggacggtggt ccgtcaatgt cgacatattg tgaaaaccaa ctgtatttcc
     6781 taaaatggca gaatatttat caatcttcat ctgttgctac ccccactact tcattatatc
     6841 ctacaacttg tacttcatct gttccatcaa tttcgacacc gtcagaaata atcgcacctt
     6901 caccaataat ggcacgttta atcttagctc cttgaccaat gatagctcca ctcatgataa
     6961 ctgaatcaag gacttccgct ccttcgcgaa cttgcgcgcc tgttgaaagg atagaatgtt
     7021 taacagttcc atcaacgaaa catccgtcta caactaatga gtcttccaca tgagcatttg
     7081 ccccgaggaa gtttggtggt gaaatcaagt ttcttgagta aatcttccat tgacggttac
     7141 gactatccaa ggcattttct ggagaaatat actccatgtt cgcttcccaa agtgactcaa
     7201 tagtaccaac atctttccaa taaccactaa attcgtaagc ataaacactt tcacctgact
     7261 caaggtaatt tggaatgaca tttttaccaa agtctgacat gccaaccttg ctcttttcag
     7321 cagcgactaa catattacga aggcgttgcc aatcaaaaat gtagattccc atagaagctt
     7381 ttgtagattt aggttgagct ggtttttctt caaattcaac aatacgattg ttagcatctg
     7441 tgttcatgat accaaaacgg cttgcttctt taagagggac gtctaaaact gctactgtca
     7501 agctggcatt attatcctta tgagactgga gcatatcatc atagtccatt ttgtagatgt
     7561 gatccccaga caaaatcaag acatactcag gattgacact gtcgatatag tcgatatttt
     7621 ggtaaatagc gtgactagtc ccctcaaacc aacgatttcc ttcacttgca gaataaggtt
     7681 gaagaataga gacacctgaa ttaataccgt ctagtcccca gcttgaacca ttcccaatat
     7741 ggttgttgag agcaagtggt tgatactgtg taacgacccc aacattgtga atccctgagt
     7801 tggcacagtt tgatagggca aagtcaatga tacggtagcg cccaccaaat tgcacagctg
     7861 gttttgcgat gctttgagtg agtttaccga gacgagttcc ttgcccacca gcaagaatca
     7921 aagctaacat ttcatttttc attttctact cctttttggt ttttatttgt gacggtttta
     7981 gtagatttca agcgacgttt gattttccat acacttgctc ccatagccgg tagggtaaag
     8041 gttaaggtct gctcataatc tttccatagt ccttcttgcg tttgaacagt ttgattatgt
     8101 tctttccaaa cgcctcccca ctcttccaac tcagtattcc atacttcttc gtaaattcct
     8161 gcaacgggta gtccgattgt aaaatctttc cgctcaacag gtaccatgtt aaagatacag
     8221 actaacattt ctcccttttt acccttacga ataaaggaaa gaacactctg gtctcgatta
     8281 tccgcatcaa tgatttcaat accatcatag ctggtatcga tttcccacag acagcgatga
     8341 tctttgtaaa actggtttag ctgagaagtg aaatacttca tcttagcatt cattgggtct
     8401 tctaggttag accattccaa ctgttcttca gatttccatt ctaggaattg accgtattcg
     8461 ctacccatga agagcaattt cttaccagga tgacaaattt ggtacgtata gagattgcgc
     8521 aagcctgcga attgattgta acgatctccc cacatcttat gcatcatact cttcttgcca
     8581 tgaaccactt catcgtgcga gaatggcaag agataattct ccttgaaaac atacataaag
     8641 ctgaaagcca ccaggttaaa gtcatattta cgatagatcg gatcttcttc gtagaaacgg
     8701 aggatatcat tcatccagcc catgttccat ttgtagtcaa atcctagacc accaatctct
     8761 ttcattcccg taatcttggt cgcagacgaa ctttcttctg caatcatcat cacatctgga
     8821 tattctaact taataacctc attcaagcgt tgaaggaaat aataaccttc atagttgaga
     8881 tttccgccat ctttattagg tgtccatgga gcatcatcat agtccaaata gagcatgttg
     8941 ctaacagcat ccacacgaat accatccaaa tgatagacat caatccaatg cttaatgcaa
     9001 gaaattaaga aggactggac ttcatttttt ccaaggtcaa aattaagggc accccaacca
     9061 tggttatgag ccttattatg gtcttggtat tcaaaagtcg gtgtcccatc ataataggct
     9121 aaggcatcat cgttgatggt aaagtgacct ggtacccagt ccacaataac cccaatatta
     9181 tgggtatgac actcctcgac aaaatcttga aactcctctg gtcggccata agcatgctct
     9241 aaagcgaagt aacccataag ctgatacccc caactcaagc ccaaaggatg ggacatcaag
     9301 ggcataaact caatatgagt atagttcatt tcaacgagat aaggaatgag ttcatccttg
     9361 agctgggcaa aactataagg actgccatca gaatttcttt tccatgatcc agcgtgaact
     9421 tcataaatat tgacaggacg ctcttcaaag ccccaacgtt ttcttcgtgc cagccaaagt
     9481 ccatccttcc atttcttctc aggaagctct gttaagattg cccctgttcc tggacgagcc
     9541 tcatacctga cagcaaaagg gtcaatcttc atcagttgat gaccattttg acgtgtgaca
     9601 tgatatttgt aaatataccc ttcttgagcc atattggtaa agacttccca gaccccaaaa
     9661 tcatttctta ccattggaat ctgattttca atccagttgg taaaatcacc aaccaagtga
     9721 acagcctgag cattaggtgc ccaaacacgg aaggtatagc catgctctcc atttagttct
     9781 tccctatgtg ctcctagata atgttggaga taaaaatttt cacccgtcat aaaggttttt
     9841 aatgcttctc tattatccat atactcccct tctcctgtaa gcgttttcta tgtttttatt
     9901 atactacctt tttagagaag attcaagtaa attactatac ttctttaatt attttgaaaa
     9961 tctacaacaa gttcacttac tcgttcaatt gtaaatcaat attttttcaa aaaattgcga
    10021 aaacgccttt ctttttctac tatagtgaaa tgaaataaaa catgcgcaag tcgattaagg
    10081 aatttaatct aatttctaac aatgtcttag aaatcaaagt gtactatttt aacttcaatg
    10141 tactatatat
//
LOCUS       DBERPV010000051         9778 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.51, whole genome shotgun sequence.
ACCESSION   DBERPV010000051 DBERPV010000000
VERSION     DBERPV010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9778
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.51"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(146..493)
                     /locus_tag="ACL8C7_001879"
     CDS             complement(146..493)
                     /locus_tag="ACL8C7_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HGS1396024.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFIHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(604..2322)
                     /locus_tag="ACL8C7_001880"
     CDS             complement(604..2322)
                     /locus_tag="ACL8C7_001880"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HGS1396025.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQIPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            2555..3399
                     /locus_tag="ACL8C7_001881"
                     /pseudo
     CDS             2555..3399
                     /locus_tag="ACL8C7_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078372828.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            3521..3763
                     /locus_tag="ACL8C7_001882"
     CDS             3521..3763
                     /locus_tag="ACL8C7_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000284543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1396026.1"
                     /translation="MYQNEDLYKKGLNVELAHQQIKGFFEAEFKNRINGVLNTKIKNS
                     ALNRVNKKTIHQSNKNSMINLKQKQRKMLKNKAILC"
     gene            3757..4011
                     /locus_tag="ACL8C7_001883"
     CDS             3757..4011
                     /locus_tag="ACL8C7_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1396027.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRITNRLANDLNNVLKQA
                     DKDTPNTLTWLNSAASKAKDDDRVYKLLKTLIPGENYLSC"
     gene            4122..5228
                     /locus_tag="ACL8C7_001884"
     CDS             4122..5228
                     /locus_tag="ACL8C7_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HGS1396028.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGFEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            5186..5707
                     /locus_tag="ACL8C7_001885"
     CDS             5186..5707
                     /locus_tag="ACL8C7_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGS1396029.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKITGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAG
                     LGLGFFKKKEDEK"
     gene            5930..6799
                     /gene="gla"
                     /locus_tag="ACL8C7_001886"
     CDS             5930..6799
                     /gene="gla"
                     /locus_tag="ACL8C7_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aquaglyceroporin Gla"
                     /protein_id="HGS1396030.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            7710..8906
                     /gene="tuf"
                     /locus_tag="ACL8C7_001887"
     CDS             7710..8906
                     /gene="tuf"
                     /locus_tag="ACL8C7_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HGS1396031.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            9290..9427
                     /locus_tag="ACL8C7_001888"
                     /pseudo
     CDS             9290..9427
                     /locus_tag="ACL8C7_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            9530..9778
                     /locus_tag="ACL8C7_001889"
                     /pseudo
     CDS             9530..9778
                     /locus_tag="ACL8C7_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         3128 a         1805 c         2010 g         2835 t
ORIGIN      
        1 aaaaattgat ttgacttcca aaattaaaat gttctgtaat gaaatgctga tgtaactgtt
       61 ttaggaacaa taaaacgcat aatatcaagg tttttgcacc ttacattatg cgtttttgtg
      121 attttaagac ttgttagctg attttttaca atcctgcgaa atctttgatt tcttgtgctg
      181 acattgaaga gtcgcaacgg acgttgattt gtccatctgt aatatgaata aaacctggta
      241 cagttgggat tccatagcgt gagcggaatg cttgcaaatc attgagttgg cttggttctt
      301 cactattgat gaagtaaatg tgagctttgg tttcagctac gacacctgac aatgtacctg
      361 caaatttacg gcagtaaggg caagttttgc gaccgataaa gaaggttgca gtttcttttt
      421 tatcaagagc ttcttgcgca cgcacaactg tagtgacttc aaggtctttg atgttatcta
      481 aaaattgttc catgagatta cctcgctttc attgataagt ctagtatgcc ataaagtttc
      541 taaaattgct tagatttgat acgaaaaaag atgaggttgg ttggtctcat cttttatagg
      601 tctttatttt acaaatgcat tgatttctgc ttcgatgtta gcaatcttag cttgtgattc
      661 ttcgttggtt tcccctacaa ctgcaatgta gaacttgatt tttggttctg tacctgaagg
      721 gcgaacggca atccatgaac cgtcagcaag tgtgtatttc aacacatcac ttggaggagt
      781 tgtcaagttt gtaacagtac cgtcagcaac agtagcagtt tgtgccttga agtcttctac
      841 gacagtgata gctgttgcgt tccattctgt tggagcattg ttgcggaatt tagccataat
      901 cgctttgatt tgttcagcac catcgacacc tgaaagagta acagagattg ttttttctgc
      961 gtagtagcca tattctttat agatttcttc gataccgtca gcaagtgtca aaccacgaga
     1021 acggtagtag gcagcaagtt cagcaacgac aagaacggct tggatggcat ctttatcacg
     1081 tacaaatggt ttaatcaagt aaccgaagct ttcttcaaat cccatcatgt aagtgtggtt
     1141 gtgtttttct tcgaattctt ggattttttc agcgataaat ttgaaacctg tcaagacgtt
     1201 gaacatagtt gcgccgtagc tttcagcaat cttcgttacc aagtcagttg aaacgataga
     1261 tttgcagaga gcggcatttt caggaagagt tccagcgttt ttgtgagctt ccaagatgta
     1321 tttagccatg atagcaccga tttggttacc tgaaaggttg aggtagctac catctttttg
     1381 aagaacttca acaccaacac ggtcagcgtc tgggtcagtt gcgacaagaa catctgcacc
     1441 aacttgacga ccaagttctt cagcaagggc aaaggctgct tggctttctg ggtttggaga
     1501 tgttacagtt gagaagtctg ggtcagcagt tgcttgcgct tcaacaactt gaacagagtc
     1561 aaatcctgct tgggcaagag cacgacgagc caacatttca ccagtaccat gaagtggtgt
     1621 gtagacaatc ttcatgtctt taccaaattc ttcaatcaag gctgggttga tgtttacgtc
     1681 cttaacctct ttaaggtatt ctacgtcaac agcttcgccg ataacttcaa tcaagccaga
     1741 agctttttca gtttccacat cagcaacttc aactgcaaat gggttttcga ttgcacggat
     1801 ataagtagtc aaagcgtccg catcgtgtgg aggtatttgt ccaccgtctt caccgtaaac
     1861 cttgtaaccg ttaaatggag cagggttgtg gctggctgtg accatgatac ctgcgaaaca
     1921 gttgagatga cgaactgcaa atgatagttc tggagttgga cgaaggcttt caaatacgta
     1981 agatttgatg ccgtgtttag caagaactgc cgcagattca aaggcaaact caggtgagaa
     2041 gtgacggcta tcgtaggcaa ttgctacacc gcgttctttc tcgtttccac cttttgactc
     2101 aatcaaacga gccaatcctt cagtagcttg gcgaacaacg tagatgttga tacggtttgt
     2161 accagcacca accaagccac gcatacctgc agtaccaaat tcaagatttg tatagaaggc
     2221 atcttcctta gttttttcgt ccatattttc caaatcttga cgaaggtagt caggaagctc
     2281 cacaaaatca acccatttct ggtaattttc ttggtaagac attcaaattc tcctttattt
     2341 ttaaaacatt taatcagttt aattatatca tttttttagt tttagtaaaa ccttatctgc
     2401 ttcgaacatc tcttcaaacc aggtcagatt gaattttggg gttatatgat gttgaggcta
     2461 ggaaaaattc aatttcagta aaaaaagtaa gtcttctcat aacaaaacat tgatatagtt
     2521 acttagtttt aaacaagcat attataataa agctatggca tatagtactg attttaaaca
     2581 gcgagcatta gattacatca aagaggggca cagccatgtc gaggcagcca agttttttgg
     2641 tgttggcgtc agaactctct tcacgtggga aaagaaagac gtgaacaaga acacatagag
     2701 aggaaaaagc gagtcgtcaa aaaccgaaag attcctttag aggaattgaa agcctttgta
     2761 gaggctcatc cagatgcttt tttacgggaa attgcggccc gttttgattg tgctttgccc
     2821 tccgtatggg cagttttaaa gcagattaag gtcattttaa aaaagacgac cagttttagg
     2881 gaacaaaagc ctgagaaagt ttctgagttt cttgatattt tggataacct aaaagattta
     2941 ccagtcctat atattgacga aacgggaatc gaccgctacc tctatcgtcc ttatgcaggg
     3001 gctcctagag gggagaaagt ctatggcaag attagcggac ggcgttttga gcggacttca
     3061 attgttgcag gacaagtaga cggagagttt atagctccca tgatttacaa gaaaagcatg
     3121 acaagcgatt tctttgtgga gtggttcaaa acgcaactcc tacctgcttt gaagacacct
     3181 catgttattg tcatgggcaa tgctagtttt catcccaaga acattttgga tgaactctgc
     3241 atccaagata aacacttttt cttacctcta ccaccttatt caccggattt gaatcctatt
     3301 gagcaagctt gggctatctt gaaaaagaaa gtgacggatt tattaaggga agttccaact
     3361 atttttgaat gtttggaatg cttttttaaa actagatgac tataacggtt ctaaaggaac
     3421 ctatcgagta gtcattaaaa ctaaggatac tgctggttaa gagaagacgg tatacgatca
     3481 aaccattcac cgtgtagccg aaatcgttca gaatgaagac ttgtatcaga atgaagactt
     3541 gtataagaaa ggtttgaatg ttgaacttgc gcaccaacaa attaagggat tttttgaagc
     3601 agagtttaaa aatcgtatta atggagttct taatactaaa ataaaaaata gtgcattaaa
     3661 tcgtgtaaat aaaaaaacta tacaccagag caacaaaaac tccatgatca atttgaagca
     3721 gaagcaacgg aagatgctaa aaaacaaggc gatattgtgt tgaatgttga ccaggatttc
     3781 atgagcatat ctaagtctaa taaaagtggt tcagactgga agaaaacttt cacagtgagg
     3841 ataaccaata ggctagcaaa tgacttgaat aatgtcttga aacaggctga taaagatact
     3901 cctaataccc taacttggct aaactcagct gcttctaaag ctaaagatga tgacagagta
     3961 tataaactac tgaagactct tataccagga gaaaattacc tatcatgtta aggataatca
     4021 gctagaagta gaaacagata aatacacata tactgccgct agaaatggta gtaaggaagt
     4081 tggtattcaa gagtcagata tagcagcaac tctaagtgcc gatgaatata attctaatcg
     4141 ccaaactttt gagagagaat acaaatacaa aagcaaatgc ccttaataat ggttgggcta
     4201 gatctggttc tgaagagttc aaaaagttct cccactttgt aggggtagac aaagggattg
     4261 tgcgaacgaa tgtactgact ggtaaaaaac tatctgataa gattaggaaa gaagtgggct
     4321 ctggagatag caaactagga aaaggcggct atttctctac tggggatgtt ctattaggaa
     4381 aagatgttgt ttcttatacc gtacaagtat tttcagagaa taatgaaaga gtaggagtaa
     4441 acactcaaag tcaccgtgtt cagtataatc tcccaattct agctgacttt tcagtcatcc
     4501 aagatactgt ggaaccatca cgaaccgttg ttgaaaaaat cattccaaaa ctaaatattc
     4561 ccgaagaaga gaaagggaaa ataaccgaag aaatcaagaa aaagaaaaaa acctcagaat
     4621 tggcagaact aatctcagaa aatgtgaaag ttcgctatgt tgatgaacaa gggcgtttgc
     4681 tatcattgaa aaatgatact ggaattggag aaaaagaaag tgacggaacc tacattacca
     4741 ataaaaaaca actgattggt accagctaca atgtcacaga taaaaaactc agtagcatga
     4801 ctactactga cggaaaatat tatactttta aagaagcaga tacaaattct gcaagtttaa
     4861 ctgggaatat tgtaagtgaa ggtagaacag tgaccttagt ttatagagaa agcgaagcgc
     4921 caaccactgc tacagtaaca gccaattact ataaagaagg tagccaagag aagttggcag
     4981 agtctgttat aaaagctgat ttagcgatag gttttgagta taccacagaa tcaaaaacta
     5041 ttgaagggaa aacaacaact gaggacaaag aagaccgagt tatcacaagg aaaacaacat
     5101 ataccttggt agcaactcct gcaaatgcgt accagaagac ggtgcaacag ttgactatta
     5161 ctaccgtgag aatgttgagg aaacagtggt tcccaaaaca gcaacctcta ctgagacgaa
     5221 gactataacg cgtatcattc attacgttga taaagttacg aaccaaaatg taaaagaaga
     5281 tgttgttcaa cctgtaacct taagccgtac aaaaactgag aacaagatca cgggagttgt
     5341 aacctacggt gaatggacaa caggaaactg ggacgaggtt atatctggta agattgacaa
     5401 gtacaaagat ccagatattc caacagttga atcacaagaa gttacgtcag actctagtga
     5461 taaagaaata acggtaaggt atgaccgttt atcaacacca gataaaccaa ctccagaacc
     5521 aggtactcca aaaactgaaa ctccagtgaa tccagaccca gaagttccga cttatgagac
     5581 aggtaagaga gaggaattgc caaacacagg tacagaagct aatgctacct tggctagtgc
     5641 tggtatcatg accttgttag ctggtctagg attaggattc ttcaagaaaa aagaagatga
     5701 aaaataatag attttagaat ctaggaacaa ggaaaagatc acagatgtgg gctttttcct
     5761 ggttttgaga atgaggtctt tcgtgaagaa taaaaacgct tacaagtacg ttggactggg
     5821 aaactatgaa tcctattttt ttaaaaatat ttccagaaat cagttgctaa atagggtaaa
     5881 aattgataaa ataaggaata tctaaaaaat tttaaggaga atctagcaaa tggatttcac
     5941 atgggcactg aagtatgcca ctgaattttt gggaactgcc attttgatca ttcttgggaa
     6001 tggtgcagtt gccaacgttg aacttaaagg tacgaaaggt caccaaagtg gctggatcgt
     6061 catcgctgtt ggttatggta tgggggttat gatcccagcc ttgatgtttg gtaacgtatc
     6121 tgggaatcac atcaaccctg ctttcactct agggcttgca gttagcggtc ttttcccttg
     6181 ggcacaagtg gtaccttaca ttatcgcgca agtcttgggg gctatctttg gccaagcctt
     6241 agttgtggca acataccgtc cattctactt gaaaactgaa aacccaaata acatcttggg
     6301 aactttctca actatttcaa gtattgacca tggtacaaaa gaaagtcgct atgcagcaac
     6361 tgtcaatggt ttgattaatg agtttgttgg ttcatttgtt ttgttctttg cagctcttgg
     6421 tttgactaaa aacttctttg gtgctgaagt gcttcaattc atgaaacaaa aggcaataga
     6481 agcaggacaa acagttgatt tttctgactt ggctattaaa gcacaggtgg ctccacacac
     6541 tgcttcagga ctttctgtgg ctcacttggc acttggattc ctcgttatgg ctttggtaac
     6601 atcacttgga ggacctacag gacctgcctt gaacccagcc cgtgacttgg gaccacgtct
     6661 ccttcatgct ttccttccaa aatcagttct tggtgagcat aaaggcgatt caaaatggtg
     6721 gtattcttgg gtaccagtag tagcacctat cgcagcagca attgcggcag tagctgtatt
     6781 caaattcctt tatctctaag aaatagctcc tttaacattt gagtgagcac catctataag
     6841 taagagagga tcagactggt tctctctttt tgatttttta gggaaatgaa agaaactcta
     6901 aacaaactcc tcttcagcag tggtttagaa gtctcagtgg gctattccag cttcaatggg
     6961 ctatagtagg ttgcagttga aataatagac ccttgtttct aaaacattgt gagaaattgg
     7021 tttgaattct ccaatcaaat tgtgcagttt tcattctact atatattatc ggagatgggt
     7081 tccctatctt gtaagtctgc tttatagtgg attgaagttg gaatagtcct cccttctttc
     7141 tcaaacattg tgaggaattg atttaccttc ctcaacaaaa tgttcagttt ctatttcatt
     7201 ttgctataaa ataagcgatt aggggggcta ttcttcgacc tacattgact ctgctgagtc
     7261 ctatgattgt tatcgtttta tctgcaattt tatactcaat gaaaatcaaa gggcaaacta
     7321 agaagctagc cgcaggttgt tcaaaacaca gttttgaggt tgtatagtag attgaaacta
     7381 gaatagtaca catctacttc taaaacattg ttagaaatcg atttgactgt cctgaacgat
     7441 ttgccctatt cttgtttcat tttactatat aaaccagaga ctgtttacat tttcagcaag
     7501 tgagtggatg gataatgctg aaaactcctt gaaggataag tctatttagt actttctatt
     7561 aattagttaa atttttacca agaataattc acaaaaacgt tgtaaaacac ttgcaattta
     7621 gctgaaattt gataaaatag taaggaaagt tagactgtat tgcctactgt ctatctataa
     7681 aatatatttt attggaggct tttactcaaa tggcaaaaga aaaatacgat cgtagtaaac
     7741 cacacgttaa cattggtact atcggacacg ttgaccacgg taaaactacc ctaactgcag
     7801 ctatcacaac tgttttggca cgtcgcttgc cttcatcagt taaccaacct aaagactatg
     7861 cgtctatcga tgctgctcca gaagaacgcg aacgcggtat cactatcaac actgcgcacg
     7921 ttgagtacga aactgaaaaa cgtcactacg ctcacatcga cgctccagga cacgcggact
     7981 acgttaaaaa catgatcact ggtgctgctc aaatggacgg agctatcctt gtagtagctt
     8041 caactgacgg accaatgcca caaactcgtg agcacatcct tctttcacgt caggttggtg
     8101 ttaaacacct tatcgtcttc atgaacaaag ttgacttggt tgacgacgaa gaattgcttg
     8161 aattggttga aatggaaatc cgtgacctat tgtcagaata cgacttccca ggtgacgatc
     8221 ttccagttat ccaaggttca gcacttaaag ctcttgaagg tgactctaaa tacgaagaca
     8281 tcgttatgga attgatgaac acagttgatg agtatatccc agaaccagaa cgtgacactg
     8341 acaaaccatt gcttcttcca gtcgaggacg tattctcaat cactggacgt ggtacagttg
     8401 cttcaggacg tatcgaccgt ggtatcgtta aagtcaacga cgaaatcgaa atcgttggta
     8461 tcaaagaaga aactcaaaaa gcagttgtta ctggtgttga aatgttccgt aaacaacttg
     8521 acgaaggtct tgctggagat aacgtaggtg tccttcttcg tggtgttcaa cgtgatgaaa
     8581 tcgaacgtgg acaagttatc gctaaaccag gttcaatcaa cccacacact aaattcaaag
     8641 gtgaagtcta catccttact aaagaagaag gtggacgtca cactccattc ttcaacaact
     8701 accgtccaca attctacttc cgtactactg acgttacagg ttcaatcgaa cttccagcag
     8761 gtactgaaat ggtaatgcct ggtgataacg tgacaatcga cgttgagttg attcacccaa
     8821 tcgccgtaga acaaggtact acattctcta tccgtgaggg tggacgtact gttggttcag
     8881 gtatggttac agaaatcgaa gcttaattcg atttagttcc cagaagaaca attatttaag
     8941 ttagacacta aaagaatctt gcttggcaag gttctttttt tagatattga actaatactc
     9001 aatgaaaatc aaagagcaaa ctataatata ttgaaactag aatagtacac atctacttct
     9061 aaaacattgt tagaaatcga tttgattgtc ttgattgatt tgtcttgttc ttatttcatt
     9121 ttgttataga aagttagctg cagactgctc aaaacactgt ttttaggttg tagatagaac
     9181 tgacgaagtc agtaacatct atacgacaag gcgaagctga cgcggtttga agagattttc
     9241 gaagagtata atactagact caaatcaaaa agcattatac aatagtaata tgaaatcaat
     9301 taaagaagaa atccaaacca tcaaaacact tttaaaagac tctcgtacag ctaaatatca
     9361 taaacgcctt caaatcgttc tatttcgtct gatgggcaaa tcttataaag agattataga
     9421 acttttatag tggtttgaaa taagatgtga acaactctat caggaaagtc aaactaattt
     9481 atagaaatat tttagcagcc aaggtgtact gttatagatt caatacactt tagactgtaa
     9541 tcaaacaacg atttggcgaa atgtaaaaaa tatgaggagt tcggactcga ctctctcctt
     9601 caagaaacac gtggtggtcg taaccatgct tatatgacgg ttgagcaaga gaaagtcttt
     9661 cttgcccgcc atttgaaggc tacagaggca ggagaatttg ttacaattga tgccttattt
     9721 caggcttata aaaaggagtt aggtcgttcc tacacacgtg atgccttcta tcaactgt
//
LOCUS       DBERPV010000052         9490 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.52, whole genome shotgun sequence.
ACCESSION   DBERPV010000052 DBERPV010000000
VERSION     DBERPV010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9490
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.52"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(48..1028)
                     /gene="dusB"
                     /locus_tag="ACL8C7_001890"
     CDS             complement(48..1028)
                     /gene="dusB"
                     /locus_tag="ACL8C7_001890"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HGS1396032.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(1015..1887)
                     /gene="hslO"
                     /locus_tag="ACL8C7_001891"
     CDS             complement(1015..1887)
                     /gene="hslO"
                     /locus_tag="ACL8C7_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HGS1396033.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKIAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGVEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2052..3479
                     /locus_tag="ACL8C7_001892"
     CDS             2052..3479
                     /locus_tag="ACL8C7_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS1396034.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHHIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLVAIRQLLFT"
     gene            3638..5146
                     /gene="glpK"
                     /locus_tag="ACL8C7_001893"
     CDS             3638..5146
                     /gene="glpK"
                     /locus_tag="ACL8C7_001893"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HGS1396035.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQMDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            5188..7014
                     /gene="glpO"
                     /locus_tag="ACL8C7_001894"
     CDS             5188..7014
                     /gene="glpO"
                     /locus_tag="ACL8C7_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HGS1396036.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFLLRRTNHMLFMRDSLD
                     SIVEPILDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            7084..7788
                     /locus_tag="ACL8C7_001895"
     CDS             7084..7788
                     /locus_tag="ACL8C7_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HGS1396037.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAYLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            8085..8289
                     /locus_tag="ACL8C7_001896"
                     /pseudo
     CDS             8085..8289
                     /locus_tag="ACL8C7_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846447.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(8376..8963)
                     /locus_tag="ACL8C7_001897"
     CDS             complement(8376..8963)
                     /locus_tag="ACL8C7_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1396038.1"
                     /translation="MFVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNILSDEVLE
                     VVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVNTIHGNKQ
                     ANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSPYPYYITS
                     TYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            9117..9314
                     /locus_tag="ACL8C7_001898"
     CDS             9117..9314
                     /locus_tag="ACL8C7_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000930586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1396039.1"
                     /translation="MLNAKIFYIFLCLIVIETTGLLLLKRGLEMGYLDTEAIILAVFS
                     FAFYNLCSFAWVCSTIKNNKK"
     gene            complement(9257..>9490)
                     /locus_tag="ACL8C7_001899"
     CDS             complement(9257..>9490)
                     /locus_tag="ACL8C7_001899"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1396040.1"
                     /translation="LPHDSQAWESLLGAPVAGTHRGLTPQIYDMPVVLQKNDDLNRRF
                     AKINMHFFFFENTSIYFLLFFIVEQTQANEHRL"
BASE COUNT         2711 a         1901 c         2163 g         2715 t
ORIGIN      
        1 gcagttcatt ttgagctttc ccgtttttct gagttgtaga tgtaagacta tgccttctcc
       61 aattgcaaga gggcttcaat ctctgctagg gtgctagctt gcgaaatggc tccacggagt
      121 ttggcagcgc cagatgttcc acggagatag tgaggagcga ggccgcggaa ttcacgaact
      181 gcgacgtttt ctcctttgag gttaatcaat cgtttcaagt gttcgtaggc gatcttcatc
      241 ttgtcttcaa aggtcaaatc aggtaggatt tctcctgttt caaagtaatg gttgatttgg
      301 ttgaagaggt aaggatttcc catggcagct cggccaatca tgactgcgtc agcaccaact
      361 tcttcgatgc gttgcttggc ttcttggaca gtacggatat caccgttggc gatgaatgga
      421 atcttggtta gagcttgggc aaccttgtaa agggtctcaa ggtctgcgtg gccagtatac
      481 atttgttcac gggtacggcc atgcatggcg agggcagaaa cacctgcagc ctcagcagcg
      541 agggcatttt ctactgccag agatgggtcc gcccagccgg tacgcatttt gacagtaagt
      601 gggatatcaa ggacagactg gaccttgttg atgatagagt agatcttgtc aggatccttg
      661 agccacatag caccagcttc gttcttcacg attttgttga cagggcagcc catgttgata
      721 tcgacgatat cggtcttagt gttttcttgg ataaattctg ctgcgcgtgc taggctgtct
      781 tcatcgctac caaaaagttg gatagagaca gggttttcgc cctcatcgat atgaagcatg
      841 tgcagggttt tttcgttgtt gtattggatt cccttgtcag agaccatttc cattacaacg
      901 agtccagctc cgagctcttt tgcgatggta cgaaaggctg agttggtcac gccagccata
      961 ggcgctaaaa cggtacgatt gggaatctca acattgccaa tcataaaagg tgtattaaga
     1021 tttgtcacga atgagttcct ccaggtcctt ttcatcaaag ttgtaagtag tttggcagaa
     1081 ttgacaagtg atttctaccc cgtggtcttc ctctttcatt tcctgtaagt ctgagcttgg
     1141 aaggctggca agagcgttca taaagcgttc atggctacag tcacattgga aacggatttc
     1201 ttcttcagaa agacgcttgt aggcttcgtc cccgtagata gccttgagga gggcttcgat
     1261 atggtcgtcg ctttcgagaa gagtagagat agctggcatt tcttggatgc gtttttcaaa
     1321 gcgagcaatc tcttctttct tggctcctgg caagacttga actaggaaac cacctgcaat
     1381 cttgaccttg tcttcctcgt ccaaaaggac attgaggccg accgctgaag gcgtttgttg
     1441 gctttcagta aggtaaaagg caaggtcttc accgatttct ccagagatga ggggagttat
     1501 agagttgtaa ggatttccag taccgtagtc tgtgataacg aggaattgac catttccaac
     1561 aaaaggtccg actaggactt caccagtcgc agtctttttg atgtcaacac caggattttg
     1621 aacgtagcct ttgacgttcc ccttggtatc agcgacggtg ataatagcac ctagagagct
     1681 agatcccaac accttaactg taagtttggt atttcctttt tcattggctg cgagaatctg
     1741 gctggcgata agagttcgac caagcgctac agttgagcta gcttgggttt gatgtttttc
     1801 ttgagcagtg cggacggttt cagtgctatc aaggacaaaa gcacgaaagg ctccgctttc
     1861 tgatatagtt ttaataattt tatccatagc tactatttta gcataaaaat gcccaaaggg
     1921 ggagccgtgt gtttactgat tttcaggata atggaccagg aaatcagcat gaaaataaaa
     1981 agagaaacag attatttcag catttgtcag atttatgcta tgcttaaggt agaaaatgaa
     2041 aggggtaaca aatgtattta ggagatttga tggagaaagc cgagtgtggt caattttcaa
     2101 tcctttcctt tctattacaa gagtctcaga cgactgtcaa ggctgtaatg gaagaaacag
     2161 gattttcaaa agcaacccta accaaatatg tcaccctgct caatgacaag gctttggata
     2221 gtggcttaga gctgactatt cactcagaag atgaaaatct gcgtctgtct atcggtgcag
     2281 ctaccaaggg gagagatatt cggagcttgt ttttggagag tgctgttaaa taccagattt
     2341 tggtttatct tctctaccac caacagtttt tagcccatca gctggctcaa gaattggtga
     2401 ttagcgaggc tacgcttggt cgtcacttgg ctggtttaaa tcagattttg tcagaatttg
     2461 atttatccat ccaaaatgga cgttggcgag gtccagagca tcatattcgc tatttctatt
     2521 tctgtctttt ccgaaaggtc tggtcgagtc aggaatggga aggtcacatg cagaaaccag
     2581 agagaaaaca ggagattgcc aatttagagg aaatctgcgg tgcaagtttg tctgtggggc
     2641 agaaattgga cttggttctc tgggctcaca tcagtcaaca acgtcttcgg gtcaatgctt
     2701 gtcagtttca agtcatagaa gagaaaatgc gagggtattt tgacaatatc ttctatcttc
     2761 gtttgctgag aaaggttccg tccttttttg ctgggcaaca tattccacta ggagttgagg
     2821 atggtgagat gatgatattc ttctcttttc tcctatctca tcgcattctt cctcttcata
     2881 ctatggagta tattcttggt tttggagggc agttggcaga tttactgacg caattgattc
     2941 aagaaatgaa gaaggaggaa ctattggggg attatacaga ggaccatgtc acctatgaac
     3001 tcagtcagct ttgtgctcaa gtctatctct ataagggcta tattttacag gatcgctaca
     3061 agtaccagtt agagaatcgt catccatatt tactgatgga acatgatttt aaagagacag
     3121 cagaggagat ttttcatgct ctacctgctt ttcaacaggg gacagattta gataagaaga
     3181 ttctctggga atggctccag ttaatcgaat atatggctga aaacggtggc cagcatatgc
     3241 ggattggtct ggatttgaca tctggttttc ttgtcttttc aaggatggca gccattttga
     3301 aacggtattt ggaatacaat cgttttatta ccattgaagc ctatgaccct agtcggcatt
     3361 atgatttgct ggttaccaat aacccgattc ataagaagga acagacacca gtctattatt
     3421 taaaaaatga cttggatatg gaggatttgg tagcgattcg ccagttatta ttcacttaaa
     3481 aggcttggtt aatccaggtc ttttttgtga aattcacaca atctcctcac atttttttaa
     3541 aaattaaaaa aagttgataa acaagaaagc gctttatttt gtatactagt aagtgtaaag
     3601 aggaaacacc tcaagatctt tatcaggagg acagtacatg tcacaagaaa aatacatcat
     3661 ggccattgac cagggaacta caagttctcg tgccatcatt ttcaacaaaa aaggggaaaa
     3721 ggttagctcg agtcaaaaag agtttaccca gattttccct caggcaggtt gggttgagca
     3781 caatgccaat gaaatttgga actctgttca gtcagttatt gcgggtgctt tcatcgaaag
     3841 tggtgtcaag ccaaatcaaa tcgaggcaat cgggattacc aaccaacgtg aaacaacggt
     3901 tgtctgggat aagaaaacag gacttcctat ctacaatgct atcgtttggc agtcacgcca
     3961 gacagcacct ttggctgagc aactaaaaag ccaaggttat gtggaaaaat tccatgaaaa
     4021 gactggtttg attattgatg cttacttctc tgctaccaag gttcgttgga ttttggatca
     4081 tgtagaaggt gctcaagagc gagcagaaaa aggggaattg ctctttggta ctatcgatac
     4141 ttggttggtt tggaaattga ctgacggtgc ggctcacgtg actgactact caaatgcagc
     4201 tcgtaccatg ctttataaca ttaaagaact caaatgggat gatgagattt tggaaatcct
     4261 taacattccg aaggctatac ttccagaagt tcgttctaac tccgaaatct acggcaagac
     4321 agctccattc catttctacg gtggagaggt gccaatctca ggtatggctg gggaccaaca
     4381 agcagccctc tttggacagt tggcttttga gccaggtatg gttaagaata cttatggaac
     4441 aggctctttc atcatcatga atactgggga agagatgcag ttgtctgaaa acaacctctt
     4501 gacaaccatt ggttacggaa tcaacggtaa ggtttattat gccttggaag gttctatctt
     4561 catcgcagga agtgctattc agtggcttcg tgacggtctt cgcatggttg aaaattcacc
     4621 agaatctgaa aaatacgctc gtgattctca caacaacgat gaagtttatg tcgttccagc
     4681 ctttacaggt ctaggcgctc catactggaa ccaaaatgct cgtggttccg tctttggttt
     4741 gactcgtgga acaagcaaag aagactttat caaggcgact ttgcaatcta ttgcttatca
     4801 agtgcgtgac atcatcgaca ccatgcaaat ggatactcag accgccattc aagtactgaa
     4861 ggtggatggt ggtgcagcca tgaacaactt cctcatgcag ttccaggcgg atattttagg
     4921 cattgacatt gcacgtgcta aaaacttgga aacaacagct ctaggagcgg ccttcctagc
     4981 aggtttgtca gtagggtact ggaaagactt ggacgagttg aaactcttga acgagacagg
     5041 agaactcttt gagccatcta tgaatgaatc tcgcaaggaa caactctaca agggctggaa
     5101 gaaggctgtg aaagcaactc aagtctttgc ggaagtagac gactaatact ggcagaataa
     5161 agcgatttat ttagaaagtg tgtaaatatg gaattttcaa aaaaaacacg tgaattgtca
     5221 attaaaaaaa tgcaggaacg caccctggac ctcttgatta tcggtggagg aatcacagga
     5281 gctggtgtag ccttgcaggc ggcagctagc ggtcttgaga ctggtttgat tgaaatgcaa
     5341 gactttgcag aaggaacatc tagtcgttca acaaaattgg ttcacggagg acttcgttac
     5401 ctcaaacaat tcgacgtaga agtggtctca gatacggttt ctgaacgtgc agtggttcaa
     5461 caaatcgctc cacacattcc aaaaccagac ccaatgctct taccagttta cgatgaagat
     5521 ggagcaacct ttagcctctt ccgtctcaaa gtagccatgg acttgtacga cctcttagca
     5581 ggtgtgagca acacaccaac tgcgaacaag gttttgagca aggatcaagt cttggaacgc
     5641 cagccaaact tgaagaagga aggcttggta ggaggtggag tgtatcttga cttccgtaac
     5701 aacgatgcgc gtctcgtgat tgaaaacatc aaacgtgcca accaagacgg tgccctcatt
     5761 gccaaccacg tgaaggcaga aggcttcctc tttgacgaaa gtggcaagat tacaggtgtt
     5821 gtagctcgtg atctcttgac agaccaagta tttgaaatca aggcccgtct ggttattaat
     5881 acaacaggtc cttggagtga taaagtacgt aatttgtcta ataagggaac gcaattctca
     5941 caaatgcgcc caactaaggg agttcacttg gtagtggatt caagcaaaat caaggtttca
     6001 cagccagttt actttgacac aggtttgggt gacggtcgta tggtctttgt tctcccacgt
     6061 gaaaacaaga cttactttgg tacaactgat acagactaca caggtgattt ggagcatcca
     6121 aaagtaactc aagaagatgt agattatcta cttggcattg tcaacaaccg ctttccagaa
     6181 tccaacatca ccattgatga tatcgaaagc agctgggcag gtcttcgtcc attgattgca
     6241 gggaacagtg cctctgacta taatggtgga aataacggta ccatcagtga tgaaagcttt
     6301 gacaacttga ttgcgactgt tgaatcttat ctctccaaag aaaaaacacg tgaagatgtt
     6361 gagtctgctg tcagcaagct tgaaagtagc acctctgaga aatatttgga tccatctgca
     6421 gtttctcgtg ggtctagctt ggaccgtgat gacaatggtc tcttgactct tgctggtggt
     6481 aaaatcacag actaccgtaa gatggctgaa ggagctatgg agcgcgtggt tgacatcctc
     6541 aaagcagaat ttgaccgtag ctttaaattg atcaattcta aaacttaccc tgtttcaggt
     6601 ggagaattga acccagcaaa tgtggattca gaaatcgaag cctttgcgca acttggagtt
     6661 tcacgtggtt tggatagcaa ggaagctcat tacctagcaa atctttacgg ttcaaatgca
     6721 ccgaaggtct ttgcacttgc tcacagcttg gaacaagcgc caggtcttag cttggcagac
     6781 accttgtccc ttcactatgc aatgcgcaat gagttgactc ttagcccagt tgacttcctt
     6841 cttcgtcgta ccaatcacat gctctttatg cgtgatagct tggatagtat cgttgagcca
     6901 attttggatg aaatgggacg attctatgac tggacagaag aagaaaaagc aacttaccgt
     6961 gctgatgtcg aagcagctct cgctaacaac gatttagcag aattaaaaaa ttaagaaaaa
     7021 ataaaagagg tggagggcag cattccttgt cgcccgtccc ttctttttaa tggagacaga
     7081 aagatgatga atgaattatt tggagaattt ctagggactt taatcctgat tcttctagga
     7141 aatggtgttg ttgcaggtgt ggttcttcct aaaaccaaga gcaatagctc aggttggatt
     7201 gtgattacta tgggttgggg gattgcagtt gcggttgcag tctttgtatc tggcaagctc
     7261 agtccagctt atttaaaccc agctgtgacc atcggtgtgg ccttaaaagg tggtttgcct
     7321 tgggcttccg ttttgcctta tatcttagcc cagttcgcag gggccatgct gggtcagatt
     7381 ttggtttggt tgcaattcaa acctcactat gaggcagaag aaaatgcagg caatatcctg
     7441 gcaaccttca gtactggacc agccatcaag gatactgtat caaacttgat tagtgaaatc
     7501 cttggaacct ttgttttggt gttgacaatc tttgctttgg gtctttacga ttttcaggca
     7561 ggtatcggaa cctttgcagt gggaactttg attgtcggta tcggtctatc actaggtggg
     7621 acaacaggtt atgccttgaa cccagctcgt gaccttggac ctcgtatcat gcacagcatc
     7681 ttgccaattc caaacaaggg agacggagac tggtcttacg cttggattcc tgttgtaggc
     7741 cctgttatcg gagcagcctt ggcagtgctt gtattctcac ttttctagtt tatactcttc
     7801 gaaaatcaaa ttcaaaccac gtcagcgtcg ccttaccgta ctcaagtaca gcttgcggct
     7861 agcttcctag tttgctcttt gattttcatt gagtattaga aaacaattat gttgatagag
     7921 cttgggcaag agcccaattt cagcaaaaaa tgaagtaaat cttctcataa taaaacgcat
     7981 catatcaagc acgaaaattc cacgaggtca actacagtca gaaagctgaa caacaagcca
     8041 aaacgcccaa aaaaggcggc aaaaagcaag cacctgcaag caacgtgccg aaatggtcaa
     8101 atcctgatta tgtcaacgaa ttagacccaa aaatcgttga tatgctagta gaatttcaca
     8161 agtcacaagg cactttggaa actcccgagg cgcaagcaga aatcgcccaa aaacgtgaag
     8221 aaatcgagca aaggagagct gagcttgagg ataaaaaaac aagagctttt gaaccgcttg
     8281 aacaaataga gtttcgcaag tattatgctt acaaattact tgagcaatta actaaaatat
     8341 aaaccctgcc tttatatcta ggcagggttt atattttaga aattcacgta ggttgttacg
     8401 gtttttacat acccagtata gtttgagttt ctatagtatt cagtgataaa cttccatttt
     8461 ctttgagcaa catggatata agtacttgtt atgtagtatg gatatgggct ttgtgaatcc
     8521 aagtaagact gataagcttg tataccaaaa tatgctccac caattattgc accccatgga
     8581 ccccccaata aagcacctat cctaccaatc atataactga ttccagcacc agtcatgaag
     8641 ttagcgaatg tgttagcttg tttattccca tgtattgtgt tgacgtaatt ccaaacatta
     8701 ggatcgtatg atctaaaaga tatatttagg tcgatttcat tcttttgata agccatataa
     8761 aatgccccat tgatatagac gccgtcagca cgtcgttcaa tagtgtctac acttccatct
     8821 ggattgacaa cctcaagaac ttcatcgctt aaaatattta cttgcgtatc tccgaaccgc
     8881 actgatgagc cattctcaaa ctgagcctca ccagatacaa ctttagagtt tgccgataag
     8941 ctatcatcag caaaaacaaa caagcgacgg ggaaatgcta gacatacaga aaacagacat
     9001 aactagcaaa cacatgcatt taaacatctt agacataacg gaaactcctt tgtatttttg
     9061 atttttttca acttttatta tacaataaaa ccaaataaaa agaaagcggt aacaatatgc
     9121 ttaatgcgaa aattttttat atatttttat gtttgatcgt tatcgaaact acaggcttgt
     9181 tgttgttgaa aagaggtctc gaaatgggtt atttagacac agaagctatt atcctcgcag
     9241 ttttttcatt tgctttttac aacctatgtt cattcgcttg ggtctgctct acaataaaaa
     9301 acaataaaaa ataaatagac gtattttcaa aaaaaaaaaa atgcatattt atcttagcaa
     9361 aacgacgatt taaatcgtcg tttttttgta gtacgacggg catgtcgtat atctgaggtg
     9421 taagtcctcg gtgggtacct gctaccggtg ctcccaatag tgattcccaa gcctgactat
     9481 cgtgaggtag
//
LOCUS       DBERPV010000053         8826 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.53, whole genome shotgun sequence.
ACCESSION   DBERPV010000053 DBERPV010000000
VERSION     DBERPV010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8826
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.53"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..993
                     /locus_tag="ACL8C7_001900"
     CDS             <1..993
                     /locus_tag="ACL8C7_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGS1396041.1"
                     /translation="MLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKL
                     GERLFQKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQI
                     RMEIENKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILE
                     GAWFIRLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYF
                     PNEQIDTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYL
                     KHNIFRNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINKEIVVQAFLEDI"
     gene            1105..2196
                     /gene="ulaG"
                     /locus_tag="ACL8C7_001901"
     CDS             1105..2196
                     /gene="ulaG"
                     /locus_tag="ACL8C7_001901"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HGS1396042.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            2310..4286
                     /gene="tkt"
                     /locus_tag="ACL8C7_001902"
     CDS             2310..4286
                     /gene="tkt"
                     /locus_tag="ACL8C7_001902"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HGS1396043.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKKL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            4403..4702
                     /gene="yajC"
                     /locus_tag="ACL8C7_001903"
     CDS             4403..4702
                     /gene="yajC"
                     /locus_tag="ACL8C7_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HGS1396044.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            4749..5177
                     /locus_tag="ACL8C7_001904"
     CDS             4749..5177
                     /locus_tag="ACL8C7_001904"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HGS1396045.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQQYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            5179..5589
                     /locus_tag="ACL8C7_001905"
     CDS             5179..5589
                     /locus_tag="ACL8C7_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MORN repeat-containing protein"
                     /protein_id="HGS1396046.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            5889..8540
                     /gene="adhE"
                     /locus_tag="ACL8C7_001906"
                     /gene_synonym="adhC"
     CDS             5889..8540
                     /gene="adhE"
                     /locus_tag="ACL8C7_001906"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HGS1396047.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGIATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT         2808 a         1666 c         1835 g         2517 t
ORIGIN      
        1 atgttgcagg ttctacctta tttgctgtta agctgtcata atgttgaaca gtatcaagaa
       61 agacatcagg atatagagaa agaattttct ttgataagaa aaagaataga gtatcaggtg
      121 tctaagaaat taggagaacg gttgtttcaa aagtttgaaa tttctttgtc aggacttgaa
      181 gtttctcttg tagctgttct cctcctctcc tatcgtaagg atttggatat tcatgcagaa
      241 agtgatgatt ttcggcaatt aaaacttgct ttagaagaat ttatctggta ttttgaatca
      301 caaatccgaa tggagattga gaacaaggat gatttgttac gaaatttgat gatccactgt
      361 aaagccttgt tatttagaaa gacttacggt attttttcta aaaatcctct aacaaaacaa
      421 attcgatcca agtatggaga attattttta gtcactagaa aatctgcgga aattttagaa
      481 ggagcatggt ttattcggct aacagacgat gatattgcct atttgacgat tcatattgga
      541 ggatttttaa agtatacacc atcgtctcaa aaaaatatga aaaaagttta tctcgtttgt
      601 gatgaaggtg ttgcggtttc gagacttttg ctgaaacaat gcaaacttta ttttccaaat
      661 gagcaaattg acactgtatt tacaacagaa caatttaaga gtgtggaaga tattgcacaa
      721 gttgatgtag tgattactac taatgatgat ttggatagca gatttccgat tttaagggtt
      781 aatcctatcc ttgaagcaga agatattttg aaaatgctag actatcttaa acacaatata
      841 tttcgtaata agagcaaaag tttcagtgaa aatctttcta gtcttatttc gtcttatatt
      901 gtagacagca agttggctag taagttccaa gaagaggttc aaacacttat aaataaagaa
      961 atagtagttc aagctttttt ggaagatatt tgaaggacag tccaatgatg aacacaaacc
     1021 tgtgtttttc ttggtctttt ttagtgtttt gaagggtggt atactaatct caaagataac
     1081 aattatatcc aaaggaggca acatatgcca aacgtcaaag aaattacaag agagtcatgg
     1141 attttagcca ctttcccaga gtggggaaca tggttgaacg aagaaatcga agaagaagtc
     1201 gtacctgaag gcaactttgc catgtggtgg ctaggcaact gtggtacttg gattaagaca
     1261 ccagctggtg ctaacgttgt catggacctt tggtcaaacc gtggaaaatc aaccaaaaaa
     1321 gtgaaagata tggttcgtgg gcaccaaatg gcaaatatgg caggtgttcg taagttgcaa
     1381 ccaaacttgc gtgttcagcc aatggttatc gatccatttg ctatcaacga actagactat
     1441 tacttagttt cacacttcca cagtgatcat atcgacccat acacagctgc agcaattctc
     1501 aacaatccta agttagagca tgttaagttt atcggtcctt accactgtgg acgaatctgg
     1561 gaaggatggg gtgttccaaa agaacgtatc atcgttgtta aaccaggtga cactatcgaa
     1621 ttaaaagata tgaagattca tgcagtagaa tcatttgacc gtacttgctt ggtaactctc
     1681 ccagtgaacg gtgctgatga gacaggcggt gaacttgctg gcttggctgt tacagatgaa
     1741 gaaatggctc aaaaggctgt taactatatc tttgaaacac caggtggaac catctatcat
     1801 ggtgcagatt ctcacttctc aaactatttt gcaaaacatg gtaaagactt taaaattgat
     1861 gttgctttga ataactatgg tgaaaatccg gtaggtatcc aagacaaaat gacatctatc
     1921 gaccttcttc gtatggcaga aaatctgcgt accaaagtca ttatcccagt tcactatgat
     1981 atctggtcta acttcatggc ttctactaat gagattctag aactttggaa aatgcgaaaa
     2041 gatcgcttgc aatacgattt ccatccattt atctgggaag ttggcggtaa gtacacttat
     2101 cctcaagatc aacacttagt agaataccat catccacgtg gttttgatga ttgttttgaa
     2161 caagactcta acattcaatt taaagctttg ctataatata aaaatattct ttggaggtta
     2221 tccgtatgtt gcatgatacg gataattttc atataatagt aaaatagaat gtgtgattca
     2281 ataatcacct caaatagaaa ggaaattcta tgtcaaatct atctgttaat gcaattcgtt
     2341 ttctaggtat tgacgccatt aataaagcca actcaggtca tccaggtgtg gttatgggag
     2401 cggctccgat ggcttacagc ctctttacaa aacaacttca tatcaatcca gctcaaccaa
     2461 actggattaa ccgcgaccgc tttattcttt cagcaggtca tggttcaatg ctcctttatg
     2521 ctcttcttca cctttctggt tttgaagatg tcagcatgga tgagattaag agtttccgtc
     2581 aatggggttc aaaaacacca ggtcacccag aatttggtca tacggcaggg attgatgcta
     2641 cgacaggtcc tctagggcaa gggatttcaa ctgctactgg ttttgcccaa gcagaacgtt
     2701 tcttggcagc caaatataac cgtgaaggct acaatatctt tgaccactat acttacgtta
     2761 tctgtggaga cggagacttg atggaaggtg tctcaagcga ggcagcttca tacgcaggtt
     2821 tgcaaaaact tgataagttg gttgttcttt atgattcaaa tgatatcaac ttggatggtg
     2881 agacaaagga ttcctttaca gaaagtgttc gtgaccgtta caatgcctac ggttggcata
     2941 ctgccttggt tgaaaatgga acagacttgg aagccatcca tgctgctatc gaaacagcaa
     3001 aagcttcagg caagccatct ttaattgaag tgaagacggt tattggatat ggttctccaa
     3061 acaaacaagg aactaatgct gtacacggcg cccctcttgg agcagatgaa actgcatcaa
     3121 ctcgccaagc cctcggttgg gactacgaac catttgaaat tccagaacaa gtatatgctg
     3181 atttcaaaga acatgttgca gaccgtggcg catcagctta tcaagcttgg actaaattag
     3241 ttgcagatta taaagaagct catccagaac tggctgcaga agtagaagcc atcatcgacg
     3301 gacgtgatcc agtcgaagtg actccagcag acttcccagc tttagaaaat ggtttttctc
     3361 aagcaactcg taattcaagt caagatgcct tgaatgttgt ggcagctaaa ttaccaacct
     3421 tcctaggtgg atcagctgac cttgctcact caaacatgac ttatatcaag acagatggac
     3481 ttcaagacga tgccaatcgc ttgaatcgta acattcagtt tggtgttcgt gaatttgcaa
     3541 tgggaacaat cttgaacggg atggcccttc atggtggact tcgtgtatac ggtggaactt
     3601 tcttcgtctt ctctgactat gtgaaggcag ctgtccgctt gtcagcctta caaggacttc
     3661 ctgtgactta tgtctttacc catgattcaa tcgcagttgg ggaagatggt ccgactcacg
     3721 aaccagttga gcatttagca ggtcttcgtg ctatgccaaa tctaaatgtt ttccgtccag
     3781 cagatgcgcg tgaaacgcaa gcagcttggt accttgcagt gacaagtgag aaaacaccaa
     3841 ctgcccttgt cttgacacgt caaaacttga ctgttgaaga tggaacagac ttcgacaagg
     3901 ttgctaaagg tgcttatgtt gtatatgaaa atgcagccga ctttgatacc atcttgattg
     3961 cgacaggttc agaggttaat cttgctgtct cagctgctaa aaaattggct agtcaaggcg
     4021 aaaaaatccg cgtagtcagc atgccatcta cagatgtctt tgataaacaa gatgcagctt
     4081 acaaggaaga gattcttcca aatgcagtcc gccgtcgtgt tgcagtcgaa atgggtgcaa
     4141 gtcaaaactg gtacaaatat gttggtctcg atggtgccgt tctaggtatt gataccttcg
     4201 gagcctctgc cccagcacca aaagtattgg cagaatatgg ctttactgta gaaaatcttg
     4261 taaaaattgt tcgaaacttg aaataatcct aaaaatcagg gcgtaagctc tggtttttct
     4321 taccagaaaa gtaaggtaca atcttgtaaa agtagctgaa atttgatata gtagtcctat
     4381 gtaaaagaca aaggagaaaa caatgaatcc aaatattact tttttaatca tgcttgtagg
     4441 tatgatggcc ttgatgttct ttatgcaacg ttctcaaaag aaacaagctc aaaagcgtat
     4501 ggaaagctta aataaactac aaaaaggcta tgaagtgatt acaatcggtg gactttatgg
     4561 aacagtcgat gaagtagata cggagaaggg aacaatagtt cttgacgtag atggagttta
     4621 cttgactttt gaactagctg ctatcaagac agtattaccg ctgaaagaaa cagcttcact
     4681 agaaggcgca attgaaaaat aagacgggat cacgaactcc cgtttttcta taaaagaaag
     4741 gaaatgggat gaaaaaatta gtctttgtct gtctgggaaa tatttgccgt agccctatgg
     4801 ccgagtttgt tatgaaatca atgacagata actacgaaat ccaaagtcga gcaacttcct
     4861 cttgggaaca tggcaatccg attcataagg ggactcaggg aatttttcaa cagtatgaga
     4921 ttccttatga caagaacaag acatcacttc agattagtaa ggaagatttt gaagcctttg
     4981 attatattat cggaatggac gcttcaaata tttctgactt acgtcagatg tgtccagtag
     5041 actgtcaaga taagatttac tcattttcat ctgaaagtgt tccagaccct tggtatacag
     5101 gagattttga agaaacctat cgacgtgttc aagagggctg tcaagcttgg ttagaacgtt
     5161 tagaaaagga gagttaaggt ggaaaatctt acgaattttt acgaaaagta tcgtgtctat
     5221 ctgactcgtc cacgtttaga gcttttggca gtagttacca ttgttttctg tgctgtactc
     5281 gtcttttttc taaatattcc aggaaaaggt gtcttaaaac tcgataatgg aacgattgtt
     5341 tatgatggca gtcttgtccg tggtaaaatg aatggtcaag gtaccattac cttccaaaat
     5401 ggagaccaat atacaggtgg cttcaacaat ggagccttca acggaaaagg tacctttcaa
     5461 tctaaagaag gctggaccta cgaaggtgat tttgtaaatg gtcaggctga aggaaaaggg
     5521 aaactaacaa cagaacaaga agtcgtttat gaaggaactt ttaaacaagg cgtttttcaa
     5581 caaaaataaa gcctccttat caaaggaggt attattagaa ttacaaggta agcgcttacc
     5641 tgtaaatccc tttccttcca aatccctctt ccaagcaagt ttgtgaaata aaaaatattt
     5701 gaaataaatt tcacaaactt caaagataaa acctgataag aaaagaaaat gagaaaagtt
     5761 tcacaagagt ttaaaaattc tttgtgaaat gtttatgaaa ctgtttacaa agttgaaata
     5821 atacgttata ataaacttgt gaaaaaatta acaaaggata tcgttccttg aaagctatgg
     5881 aggaaaatat ggctgataaa aaaactgtga caccagagga aaagaaactc gttgctgaaa
     5941 aacacgtaga tgagttggtt caaaaagctc tagttgccct tgaagaaatg cgtaaattgg
     6001 atcaagaaca agttgactac atcgttgcca aagcatcagt agcagctttg gatgcccacg
     6061 gagaattggc tttacatgcc tttgaagaaa caggacgtgg tgtatttgaa gataaagcaa
     6121 ctaagaactt gtttgcttgt gaacacgtgg taaacaacat gcgtcacact aagacagttg
     6181 gcgttatcga agaagatgat gtaacaggat tgaccctgat tgctgaacca gttggtgttg
     6241 tttgtggtat cactccaaca acaaacccaa catcaacagc gatcttcaaa tcattgattt
     6301 cattgaagac acgtaatcca atcgtctttg ccttccatcc atcagctcaa gaatcatcag
     6361 ctcatgcagc tcgtatcgtc cgcgatgcag ctatcgcagc tggtgctcct gaaaactgtg
     6421 tacagtggat cactcaacca tctatggaag caactagtgc ccttatgaac cacgaaggta
     6481 ttgcaacaat ccttgcaaca ggtggtaatg ccatggttaa agccgcatac tcatgtggta
     6541 aaccagctct tggggtaggt gccggaaacg ttccagctta tgttgaaaaa tcagcaaaca
     6601 ttcgtcaagc agcacacgat atcgtcatgt ctaaatcatt tgataacggt atggtctgtg
     6661 catctgaaca agcagttatc attgataaag aaatttacga tgaatttgta gcagagttca
     6721 aatcttacca cacttacttt gtaaacaaaa aagaaaaagc tcttcttgaa gagttctgct
     6781 tcggcgtcaa agcaaacagc aaaaactgtg ctggtgcaaa attgaacgct gacatcgttg
     6841 gtaaaccagc aacttggatt gcagaacaag caggatttac agttccagaa ggaacaaaca
     6901 ttcttgctgc agaatgtaaa gaagttggcg aaaatgagcc attgactcgt gaaaaattgt
     6961 caccagttat tgcagttttg aaatctgaaa gccgtgaaga tggtattact aaggctcgtc
     7021 aaatggttga atttaacggt cttggacact cagcagctat ccacacagct gacgaagaat
     7081 tgactaaaga atttggtaaa gctgttaaag ctattcgtgt tatctgtaac tcaccttcta
     7141 cttttggtgg tatcggggac gtttacaatg ccttcttgcc atcattgaca cttggatgtg
     7201 gttcttacgg acgcaactca gttggggata acgttagtgc cattaacctc ttgaatatca
     7261 aaaaagtcgg aagacggaga aataacatgc aatggatgaa acttccttca aaaacatact
     7321 ttgaacgtga ttcaattcaa taccttcaaa aatgtcgtga cgttgaacgt gtcatgatcg
     7381 ttactgacca tgccatggta gagcttggtt tccttgatcg tatcatcgaa caactggacc
     7441 ttcgtcgcaa taaggttgtt taccaaatct ttgcggatgt agaaccggat ccagatatca
     7501 caactgtaaa ccgtggtact gagattatgc gtgccttcaa accagatacc atcatcgcac
     7561 tcggtggtgg gtctccaatg gatgctgcca aagtaatgtg gctcttctac gagcaaccag
     7621 aagtggactt ccgtgacctt gtccaaaaat tcatggatat ccgtaaacgt gccttcaagt
     7681 tcccattgct tggtaagaag actaaattca tcgcgattcc aactacatct ggtacaggat
     7741 ctgaagtaac accatttgcc gttatctctg ataaagcaaa caaccgtaaa tacccaatcg
     7801 ctgactactc attgacacca actgtggcaa tcgtagatcc tgctttggta ttgacagttc
     7861 caggatttgt tgctgctgat actggtatgg acgtattgac tcacgcgaca gaagcatacg
     7921 tatcacaaat ggctagtgac tacactgatg gtttagcact tcaagccatt aaattggtct
     7981 ttgaaaatct cgaaagctca gttaagaatg cagacttcca ctcacgtgag aaaatgcata
     8041 acgcttcaac aatcgctggt atggcctttg ccaatgcctt cctaggtatt tctcactcaa
     8101 tggcccataa gattggtgcg caattccaca caatccacgg tcgtacaaat gctatcttgc
     8161 ttccatacgt tatccgttac aacggtacac gtccagctaa gacagcaaca tggcctaagt
     8221 acaactacta ccgtgcagat gaaaaatacc aagatatcgc acgcatgctt ggacttccag
     8281 cttctactcc agaagaaggg gttgaatctt acgcaaaagc tgtctacgaa ctcggtgaac
     8341 gtattgggat ccaaatgaat tttagagacc aaggaattga cgaaaaagaa tggaaagaac
     8401 attctcgtga attagccttc ctggcttatg aagaccaatg ttcaccagct aacccacgtc
     8461 ttccaatggt agaccatatg caagaaatca tcgaagatgc atactatggc tacaaagaaa
     8521 gaccaggacg ccgtaaataa ttgtttatca gtctagaagc aagacaaaaa ctcaatttga
     8581 gggaaagatc cagtactttt tctatgataa aaggcatcct atcaaggttt ttgaacacct
     8641 gataggatgc ctttttatga tattgaggcc tttttgccct ttttgaaaaa ctagaataga
     8701 aacaaaatat ataatagatt gaaactggaa tagtacactt ctgcttctaa aacattgtta
     8761 gaattcgatt tgactgtcct gatcgatttg tcctgttctt atttcatttt aatatataaa
     8821 aaatat
//
LOCUS       DBERPV010000054         8319 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.54, whole genome shotgun sequence.
ACCESSION   DBERPV010000054 DBERPV010000000
VERSION     DBERPV010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8319)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8319)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8319
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.54"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(549..857)
                     /locus_tag="ACL8C7_001907"
     CDS             complement(549..857)
                     /locus_tag="ACL8C7_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGS1396048.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(854..1162)
                     /locus_tag="ACL8C7_001908"
     CDS             complement(854..1162)
                     /locus_tag="ACL8C7_001908"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS1396049.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNTPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(1167..2462)
                     /locus_tag="ACL8C7_001909"
     CDS             complement(1167..2462)
                     /locus_tag="ACL8C7_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGS1396050.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTKFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(2480..3889)
                     /locus_tag="ACL8C7_001910"
     CDS             complement(2480..3889)
                     /locus_tag="ACL8C7_001910"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGS1396051.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTEDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYDNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            4047..4775
                     /locus_tag="ACL8C7_001911"
     CDS             4047..4775
                     /locus_tag="ACL8C7_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGS1396052.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            5234..5428
                     /locus_tag="ACL8C7_001912"
     CDS             5234..5428
                     /locus_tag="ACL8C7_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGS1396053.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(5550..5716)
                     /locus_tag="ACL8C7_001913"
                     /pseudo
     CDS             complement(5550..5716)
                     /locus_tag="ACL8C7_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558122.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(5794..7104)
                     /locus_tag="ACL8C7_001914"
     CDS             complement(5794..7104)
                     /locus_tag="ACL8C7_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HGS1396054.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNFAITNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGKTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTSIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            7341..8213
                     /gene="nadC"
                     /locus_tag="ACL8C7_001915"
     CDS             7341..8213
                     /gene="nadC"
                     /locus_tag="ACL8C7_001915"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HGS1396055.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFKRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALDDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT         2596 a         1450 c         1575 g         2698 t
ORIGIN      
        1 gatagagttg ttcacatctt atttcaattc actatagttt aatttaagag tagtatttac
       61 taaggcccaa ttaaaatcaa agagcaaacg agaaaacgat gacaaggtgt gttgcttttt
      121 gatttctaaa gagtataatg atagatctct ataaaataag tgcgaaggaa atgagctttt
      181 ataatccttt cgttttaaaa tactatctca gatattctta tatcgacaag aagtttttga
      241 gtcattccct catcatacat attaaataaa tagtggctca ttcaattttt cactagaata
      301 ataagctagt atagtaaact gaaataagat ataaacaaat aaattggagc ttaacatcta
      361 tttccagcaa ttttttagaa attgcagtgg actattctag attcaataca ttataaaaac
      421 tagagtaaaa gaaaaggatt ggatcttgtg taatgcagga tccaatcctt tcaatcattt
      481 tgtccaactt ttggaggttc ctacaatgta gccgtcatta ataaagacag atgggaacga
      541 cagtgttcct atttattttg atagagatcg atgaattctt tagatagcaa ctgaataatc
      601 tctgttgaag ccatttggtc ttctgcatgc ataaatagca aggagaatcc tattttttct
      661 ccagtagctt ctttttgtat gagattagag tgaatcttgt gcgcttctac taaggagtct
      721 tccgcttctt caactttaat tttcgcttct tttaaatttc ccgccttagc tagttggatg
      781 gcttcaataa aggatgattt ggctgctcca ctattggcaa tgagctgaaa acagatatat
      841 tccatttctt ctgtcatctt atttctccta tccatgcaag tgcttgttcc agaacttttg
      901 ctccattcat cattccgtaa tcccgcatat caatggtatc tacaggggta tttcctgcaa
      961 tttctttcac agcaagtaac tcataacgaa tttgtggccc aattagaatg acatctgctt
     1021 catggatatt ctttttagct tctgtcattg attttgcttg gatagaaatt tcaatcccac
     1081 gttcagtcgc actttgttgc atttttttaa caagcatact tgtcgacatt cccgcattac
     1141 atactaataa aatttgtttc ataatcttaa ccttccattt cttgttcaac aactttgtca
     1201 ttaactttga taaatggaat gtatagaaga actccaagtg caaagatgat gaattgaact
     1261 agaactgctc tcacgtcccc tgctgttgct aaccatgcat ttaagaatac tggtgtagtc
     1321 caaggaactt gtataaatgc aggactcatg aatcctgtaa ctgttgctaa gtagctgatt
     1381 aaaataccaa ggactggaac tgtgataaat ggaatagcta atgaaatgtt ataaacgatt
     1441 gggtaaccga ataatactgg ttcattgata ttgaagatac caggtccaaa agataattta
     1501 gccacgtttt tagaaacagc attgcgactc actaagaatg ttgctattaa taaacataat
     1561 gtagatccac taccacccat taaagcgaat gtttgtattt gtgataagtt gatgatgtgt
     1621 ggaatggctt gtccattatt tgctgcagtg atgttttcag taatgttaat taatagtaat
     1681 ggttctagga tggcactgta aataactgct tggtgaatac caaatagcca taacatattt
     1741 cctaaagagt aaataataat gaccccgatt aagcttgtac caatatgacg aattggttct
     1801 tgaataaaga ttgtaatgat tgagattaag ttcattccag ttatattgaa taataatgct
     1861 gaaacaaccc caaataagga gatgacggtc atgactggaa gtaatacgct aaatgatcta
     1921 ctaacagctg gtggaatatt ttcaccaagg ttcatttgta aagctttaac gtttgataat
     1981 tcaatgaata attctgttgc aataatcgct acgataaccc cggcgaacat tgcgcctgta
     2041 cctgtgttgt tgaatgaaag aacacctgaa atgtttaccg catcttttgc tccgtcagga
     2101 actacagaaa ctgtatttgg catcatcaca attaaagaaa ctaatgatag cattgatgct
     2161 gctaacgggt tttcgaaatc tctgttttta gctaagaaat aaccaaccat tacagcaata
     2221 atcatacctg aaatacttaa agtaccgttt gcaattgtta ttccccaata ttggaatttt
     2281 gttaatgtat ccccttggaa aatccactta aataccgtgt tgttcaaaag aacgattaaa
     2341 cctgccaaaa tatataatgg cattactgtt acgaatgcat ctcttagggt ttttaaatga
     2401 atttggttcc ctagtttacc agcaaaggtg gcaaattgat ctataaattt tgagtttttc
     2461 atctgaatat ctcctctctt tactcctcaa tttctacttc aaaaccgtta ttgtcactta
     2521 ctttgcgata ccatcttcct gagctcttga tggttctctt ttgcgtttct aaatcaacgg
     2581 agataaatcc gtaacgattc ttatatgcat tattccaaga ccagcaatca aatgcggtcc
     2641 aagcgtggta tccaaaacag tgacttccct cttcaatggc tttatgtagc catcttaaat
     2701 gttcttcata aaattcaata cgatacacgt catcgataac tccattttca tcgataaacc
     2761 gtgcttcgtt ttcaacaccc attccgtttt cactgataaa ccatggaata ttatcatatt
     2821 cttccttcac aatcatagca atatcataaa tggctttcgg aaaaatttcc caaccacgat
     2881 atggattcat gcgacgctcc ggccattcat actctttgaa gtattggtct ggcatccagg
     2941 gcgtctgata ttcctcagga tttgcttgtg cttgaacacg ttttggatgg tagtagttta
     3001 ctccaagaaa atcaaccgta tttgatttca tcagttgaag ctctttttcg gtatgactcc
     3061 ataacacgcc atctctctct agctgtttta ccaatctttc tgggaaagtt cctttaacag
     3121 ctggattcaa gaagactttg ttaaagaagt cttctgtaaa tcgacttgct tctaagtctt
     3181 ctggagaatt acttcttgga taagcaggtg tcaagtttaa aataatccca atctttccat
     3241 caagtcctaa tgagcgatat agttgaatca cttttgcact agcaaggttt agattataga
     3301 tgacttgtac ggcctctttt ccctttcctt ttagatttgg ataatggaaa gcatataagt
     3361 atcctgcttc tggaatgacc attggctcat tgaaagttgt ccagtaatga accttatctc
     3421 caaagcatgt gaaagcagtc ttggcaaact tcacgaataa ctccactaca tgtttgcttt
     3481 cccaaccacc gtatttttga agaagttcca ctggtaaatc aaaatgatgt aaattcatca
     3541 caagatccat ctggttcttt ttagcttctt caatgatggc attgtagaaa gcaatacctt
     3601 ttggatcagg ctcacctgtc tctaaattct tgatgagtcg actccattgg atggaagtgc
     3661 ggaaagaatt aactccaatt tccttcatca agtggaaatc ttcggtgtaa gtatgaaaaa
     3721 agttactggc tacaagaggt ccgacattat cgaaaaaatc ttctggatgc gttttgaacc
     3781 agtagtccat cacattttca tgtacttttc catattgacc ttctgtctga ggtccgctag
     3841 aagcagctcc ccaccaaaac agattaggaa atactaactt ttttttcatg ctcaacctcc
     3901 tttctattat tctatacata aagtatagca taattttaaa atttgtctag acatttttaa
     3961 aaattgttga tacatatctt gtgtttgcct catttcttga actttgttat actactatta
     4021 gaatattata gagagaacca gattaaatga gtacaaaata tttatttatt tacaatgaga
     4081 ttcgtgaaaa gattctttgt aataaatata ccatgaacga acaattgcct gatgaaatga
     4141 cattagctaa acagtttgcc tgtagtcgaa tgacgatcaa aaaagcttta gacttgttag
     4201 tttctgaggg cttaattttt agaaaacgtg ggcagggaac ctttgttctc tctcgtggca
     4261 gctcaaaaag aaaattaatc gttccagaaa gagatatccg gggactgaca aaaatatctg
     4321 aagatgctca ttctacaatt gactcgagga ttattcactt caaattagaa tttgcaaatg
     4381 aatttttagc agaaaaacta caggtcgctt tgcagagtcc agtttataat atttaccgtc
     4441 tgcgtattat tgacggtaaa ccttatgttc tggaacaaac ttatatgagt accgatgtta
     4501 ttccaggtat tactgaagat attttacaaa aatcgattta caattacatt gaaggaaagt
     4561 taggattgca tattgccagt gctacaaaaa tcttgcgagc ttcttctagt tcagaaaatg
     4621 agcaacatta cttgcagctc cttccaacgg aaccggtatt tgaagtagaa caagtggctt
     4681 atttggataa cggaactccg tttgagtact cgattagtcg tcatcgctat gatttatttg
     4741 aatttaattc ttttgcatta cgacattcct cctaggagaa aatgtgaaaa tgaagccaat
     4801 cttttacaga ctctagttta agaaaaattt aaaacagggc aagaaggtcc catctatgct
     4861 taaatggttt ctcttttcta aataagatag ctttaaaaga gtgatcgttt tatccatcat
     4921 gttgaaaaat atcttcgtat agcttataga gtaggtactg aaattgttca cctgatctac
     4981 ttcttatagt tatttagttt taaatagtgt ttcaaacatt cttacactga cgagaagttt
     5041 ttgagtcttt tcttgtaaca catatagtat actgaggtta gaatagtaga ctgtgacttc
     5101 taaaaaattg ctagaaatga atttcaatct cccaatttat ttgttcatat cttcttttaa
     5161 tatattaaat aaattctgaa tcataatcat ttaaaaaaat tttatttttt atttttcatt
     5221 acgaataata tagatgaagg ggaaagagta tgaaaacaga actgtttctt ttgctattag
     5281 ttcaaaagga gaaaaaatga aagtagaaaa tatttcgtat agggtggatc atcgtatatt
     5341 gtttgataat atttcttttg atacttcgag ttcaggcgtg acattaatta ctggtaaaaa
     5401 tggtacagga aagtcaactt tactatagta gattgaaact agaatagtac acatctactt
     5461 ctaaaatatt gttagaaatc gatttgacta tcctgatcta tttgtcctgt tcttatttca
     5521 tttcactaca tctcaaattg agtatgacga agtgcgctcc catgtcctgg gaacgcactt
     5581 tcttcatatt tttcatattc ttgaatccat cgataaagac tattgggatg aatttttaaa
     5641 gttgaactaa tcatttttac aggatgaggt ttacagcaga gagtttgaag gctttatcaa
     5701 aggtttttct tggcataatg acttttcctc gtttccactt aattttgtgt ctactttatt
     5761 ataccaagtc cacccttaag ttagataata aatctaactt aaggaagcta gaaggatgag
     5821 aatccaggtg gtcaagagtc ccaaacttaa gctgatgggg acacccagaa taatttgctt
     5881 tttgaaggca aggccacgtt cctctatatt gggaagtgag agttgaatga gagaaccagc
     5941 tgatgaaaag ggtgagatat tagtagatag agcgccaata acggtggctg ttgtgagtaa
     6001 gtgaatatca atctggggat tttgagcact gatgatagca atgatgggaa agagggctgg
     6061 agctacaacg gatagggtgg aactaaagag tgacatcact ccggctatca cacaaaagaa
     6121 cagaggtaac cagaaatgag gaatggatgt tgtcatgagg tgccctatca gtgtgactaa
     6181 acctgacttg accgctagag acattagtaa gctcatgccg cagagcatga taattgtagc
     6241 ccagggaacc ttagctaaaa tggcttcttg cttccctaat ttgagcctta aggcgaggca
     6301 gaccatgagt attgagacaa agccaatatc aaatgttttt tgataagtag ctatccaggc
     6361 gatgtttggg aaaatgagat gcaacaaggg aaaaagccaa accaaaacca tgctgctgat
     6421 catgagcaag gtggtttgtc tttgaacctt gctgaggagt ggtggttggt caatagtcaa
     6481 ggatgagttt gtttttccct tactatagtg actgtaacag gataataaaa gcaagacgat
     6541 gagtgggtag ataatgctga cgataaagat atgattgcca agtgaaaaag cttgctcttc
     6601 ccatcccatt tgcttaaaca ggccttgaaa gacaatgcct gagctactgg ttatcaaatt
     6661 agcccctcct gaagctcccc aattgacggc ttgagctcca atcaaagggt gtttgtccgc
     6721 tttttgacag agggtaatcg ctagaggaca gcaaacggcc atagtagtga aaaatccagc
     6781 acctaaagca gacaaaaggg ttgccatcag gtataaaatc atgtagaggg cgttagggta
     6841 ggtgcgtgtg cggtagagaa tgtgttgagc caaaacatca agagtaccgt tagttattgc
     6901 aaagttataa aagagagaga cgctaaaaat ggtaaaaaag agtgaggttg gccaaaaatg
     6961 aagaagttct ttggggctta atcccatgag agtggttgcg atgaggtaag aaaaagcaat
     7021 agccagcagg ccaatattga ttttggtgcg gtaaccaatt ccaatggcta gagcaatggc
     7081 gctaatcatt attaaatgaa tcattgaatt gtcctttcag ttagaatatg gaaataggtt
     7141 ggcaattttg gcgctcaaaa gaccacctgt ttcctattgg tacttgacta ttatacacaa
     7201 aaaaaataca attgtcttga caattgtatt gacacttgtt agaattaaaa atgaggtatt
     7261 caggcttgtg atttcctatg gaagttaata gtgattgcct ctaatgctta caagtgatat
     7321 taaaaataga ggacttagtg atgtcaatca tttcaactga tttaacccct tttcaaatag
     7381 atgatacatt gaaagcagcc ttgcgagaag atgttcattc cgaagattac agtaccaatg
     7441 ccatttttga tcatcatggc caagccaagg tgtcgctttt tgccaaggaa gctggtgttt
     7501 tagcggggct aaccgttttt aaaagggttt ttaccctatt tgatgccgag gtgaccttcc
     7561 agaatcctca tcaatttaag gatggggatc gtttgactag tggcgatttg gttttagaaa
     7621 tcataggctc ggtgagaagt ctcttaacat gtgaacgcgt tgccttgaat tttttacaac
     7681 atttatcagg gattgcttcg atgacagctg cttatgtaga agccttagac gatgattgca
     7741 ttaaggtatt tgatactcga aaaactactc ctaatttacg tctttttgag aaatatgccg
     7801 tgagagttgg cggtggctat aatcatcgct ttaatttatc agatgctatc atgctaaaag
     7861 acaatcacat tgcggcagta ggtagtgttc aaaaggcaat tgctcaagcg cgtgcctatg
     7921 ctccttttgt gaaaatggtc gaggtggaag tggaaagcct tgctgctgcc gaagaagctg
     7981 cggcggcggg tgctgatatt atcatgttgg ataatatgtc attggaacag attgaacagg
     8041 ccattaccct aattgcagga cgttctcgga ttgaatgttc tggaaatatt gatatgacca
     8101 ctattagccg ttttcgtggt ttagcgattg attacgtctc cagtggtagt ttaacccata
     8161 gtgctaagag tcttgatttt tccatgaagg ggttaaccta ccttgatgtc taagttgtaa
     8221 aataaactaa ctttttaaag gatgtctttc ctctagaacg agttttatgt cagatagttt
     8281 aaacgcctct tcaaatatag taaaatgaat caaaaatag
//
LOCUS       DBERPV010000055         7820 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.55, whole genome shotgun sequence.
ACCESSION   DBERPV010000055 DBERPV010000000
VERSION     DBERPV010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7820)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7820)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7820
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.55"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            15..1076
                     /gene="dinB"
                     /locus_tag="ACL8C7_001916"
     CDS             15..1076
                     /gene="dinB"
                     /locus_tag="ACL8C7_001916"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HGS1396056.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKGKTYGKILLAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSKKERGVRLLGITMTGF"
     gene            complement(1223..2068)
                     /locus_tag="ACL8C7_001917"
     CDS             complement(1223..2068)
                     /locus_tag="ACL8C7_001917"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HGS1396057.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            complement(2099..2236)
                     /locus_tag="ACL8C7_001918"
     CDS             complement(2099..2236)
                     /locus_tag="ACL8C7_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001270407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1396058.1"
                     /translation="MRYQTHYQLKQKLWLDPFGNRQAIGGNELIHSGLFQVYHLGFGS
                     S"
     gene            2323..3111
                     /locus_tag="ACL8C7_001919"
                     /pseudo
     CDS             2323..3111
                     /locus_tag="ACL8C7_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(3493..5382)
                     /locus_tag="ACL8C7_001920"
     CDS             complement(3493..5382)
                     /locus_tag="ACL8C7_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HGS1396059.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGGEKALQVGMG
                     ALTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDQAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSTAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            5520..7085
                     /locus_tag="ACL8C7_001921"
     CDS             5520..7085
                     /locus_tag="ACL8C7_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HGS1396060.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            7085..>7820
                     /locus_tag="ACL8C7_001922"
     CDS             7085..>7820
                     /locus_tag="ACL8C7_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS1396061.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEEIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYL"
BASE COUNT         2477 a         1729 c         1471 g         2143 t
ORIGIN      
        1 aaaaggtgct aggcatgttg atttttcctt tgttaaatga tttgtcaaga aaaatcatcc
       61 atattgacat ggatgccttt tttgctgcag tggaaatcag ggataatcct aaactcagag
      121 gaaaacctgt cattattgga agcgaccctc ggcaaacagg tggacgggga gtcgtttcta
      181 cctgtagtta tgaggcaaga gcttttggtg tccattctgc catgagttcc aaggaagctt
      241 atgaacgttg tccccaggct gtctttatct cagggaatta tgagaaatac aagtctgtgg
      301 gactccagat tcgagctatt tttaagcgct atacagattt gattgaaccc atgagcattg
      361 acgaagccta tttggatgtg acagaaaata aactcggtat caagtcagcg gtcaaaattg
      421 ctcgcctcat tcaaaaagat atctggcaag aactccatct aactgcttcc gcaggcgttt
      481 cttacaacaa attcttagct aaaatggcga gtgattatca aaaaccacat ggtttgacag
      541 tgattctacc tgaacaggct gaggattttc tcaaacaaat ggatatttcc aaatttcatg
      601 gagtaggaaa aaagacagta gaacgtcttc atcaaatggg cgtttttact ggtgctgatt
      661 tacttgaagt tcctgaggta accctaatag accgttttgg tagactaggc tatgatctgt
      721 atcgaaaggc tcgtggcatt cacaactctc cagtcaaatc caatcgcatc cgtaaatcaa
      781 tcggcaaggg gaaaacctac gggaagattc tccttgctga ggaagatatc aaaaaagagc
      841 tgactcttct atcagaaaaa gtcgctctca atctacatca acaagaaaaa gctggaaaaa
      901 ttgtcatttt gaaaatccgc tacgaggact tttcaactct taccaaacga aaaagtcttg
      961 ctcaaaaaac acaagatgct agtcagataa gccaaatagc cctgcaactc tatgaagaat
     1021 taagcaagaa agaaagaggt gtccgcctat tggggattac catgactgga ttttaaagct
     1081 caatgaaaat caaagagcaa actaggaggc tagccgcagg ctgctcaaaa cactgttttg
     1141 aggttgcaga taaagctgac gcggtttgaa gagattttcg aagagtataa aaccttgaag
     1201 agttgcccct tcaaggtttt tcttatacaa ataaacggac aaaactgtaa agtagcaaaa
     1261 cactaccaag cacgatacgg tatttaccaa aaagggtgaa gtcgtgtttt ttcacatagc
     1321 tggtcaagaa gcgaatagcc accatgctga ccgcaaaagc tactcccatc gcgaccaaga
     1381 gcaaaaacaa ttgcccaaag ctcaagagtt ctccggcttt cacaaatttg aaaatcttta
     1441 aggcactagc tccaaacata acaggaatcc caagatagaa ggtaaattct gtcacaactg
     1501 aacgactggt tccatttaac aaaccaccga caatcgttgc acctgaacgg ctagtccctg
     1561 gtaaaagagc aagaacttgg aagagtccga tatagaaagc ggtcgtataa ggaagcttgt
     1621 ccaactctgt tacacttggc tcgatagcac gcgctttatt gcgcttttcc aaatagatga
     1681 aggcaacccc gtagataatc aacatgagag caactgaaac catgttatgg aagtgggtat
     1741 caaaccaatc atcaaattta aagacaccaa gtaaaggtaa agtagcaatc aagaccttca
     1801 accatagtct ccaagtctta cgaacttcct gtttgtcctt agtcggttta aaaggattga
     1861 gcttgttaaa ataaatcacc ataactgcta aaatagcacc aagctgaatc acgacattaa
     1921 acatggacat aaaggcttca ttttgatttt ggtattggat gaattcctct gctaaaatca
     1981 agtgacctgt actggaaatc ggcaaccatt ccgtaattcc ttcaacaatc ccgaagaaga
     2041 tagattttaa aatttcaata agatacatag attactccct atattataat tagcgcagtt
     2101 agctactgcc aaagcccaag tggtatactt ggaataagcc actgtggatt agttcatttc
     2161 ctccaatcgc ttgacgattt ccgaaaggat ctaaccacag cttttgtttc aattggtaat
     2221 gagtttgata acgcatagac gttttatctc gtctaaggta acaaggcaaa aagttcgtgg
     2281 ataaccaagt agacttgaaa tactatatct ggaggtactc ccatgcttta tgtgggcatt
     2341 gatatcgcta aaaataaaca cgatgttaca gccttgaatg ttccaggaaa aactgttctt
     2401 aaaccactca ctttttcaaa taataaagct ggttttgaac tcttagatct gtctcttcga
     2461 cagctcaacc aagactgtct catcgctctt aaacttcttt ctgaccccaa tcgtgaacaa
     2521 tttcaacacg ataatcggca agtagaccta aaaatactgg ctagacatat tcatcgtctc
     2581 aagaaaaaac agtctgattg gaaagtacaa tacactcgtt gtcttgatat catctttcct
     2641 gagttggata aaatcgttgg aaagcattca gaatatacct accaactctt gacgcgctac
     2701 cctaatcctc agaaaaggat tgaggcagga tttgataagc tgatagaaat taagcgattg
     2761 accgcttcta aaattcagga tatcctctca gtcgcacctc attctatcgg aacaacatct
     2821 cctgctcgtg aattcgaaat catcgaaaac atcaaacatt acaagaggct cattgacaag
     2881 gcgaaaaaat gtgtcaatga cttgatggct gagttcaact cggtcatcac gacggttact
     2941 gggattgaga atcgtttagg ggcggtcatt ttagccgaga ttcgaaatat tcatgccttt
     3001 gataatcctg ctcaattaca agctttcgct ggactggatt cttctattta tcagtcaggt
     3061 cagattgatt tagcaggaag aatggtcaaa cggggttccc ctcatctgcg gtaggtactc
     3121 atacaagctg ccaaagcatg ccctcgcttt tcacctgctt ttaaggccta tcttaagact
     3181 aagttagaat aaggaaaaca ttacaatata gccatcatcc accttgcaaa aaaacttatc
     3241 cgaaccctgt tttatatcct aaaaaagagc tgccatttga cgaacaaaaa gtgatataat
     3301 ttctgaaatt aacacaggat tacctttgaa aaaatggact ttttcaatag ctttttgccg
     3361 tgctctaaaa tcatcgccaa atcatcaaat tgaaataaga aatagtttag ataaaactat
     3421 tgacttttct tatagtttgt cttttttcta tcttccatta tatcatactt tttcagtcta
     3481 tggtagctct ctttaaaagg caccgatact gccgccacct ccgcctccag agaagccacc
     3541 accagaactt ccacttccag aagatacaga gtaggtgctt gctgtatttg cgacactagc
     3601 ataatggctc atttgtgctg ttgaatgata aaacatactg tgccagccat aagctacata
     3661 gagattgata tctggatttt ccacttgaat ctgatgaacc ttcatcaaat gactaacctt
     3721 gtccgcatag ccaaataagg tcgcatagac caagaggcga ttccagacca caatactttc
     3781 cagttcagcc tgatccaatc gtgcaatctc acgcaacata ttttcaaaac tggtccagag
     3841 atagtagacc tcagctcccg cttcatttag aacaccatca cgattatcta gtcgaagctt
     3901 ccaataatag aaaacagaca aaactaaccc tagaaaacca agtattggca aagggaggta
     3961 aagatagcca tgaacgtcta aactgtacaa gaacaaacca aatccgataa ataggggcag
     4021 gatagtcaag gcacccatac ccacttgcaa ggccttttcc ccaccagtta aaggacgata
     4081 ataatctggg agcccccaga aggaaactcg ttttctcact ccttcttgca tctggttcaa
     4141 tacctcttca aaagaagatt tgagttgaag ccctcttgct tgaatccgtt tttcatcaga
     4201 aactttggct ctacgataaa gactatcaga taccttgtaa tccgcaaaca aattggaaag
     4261 agtttcttct tttttacctg aaaaagctag atttaggcag tctttctcaa agcttgacaa
     4321 accatcttct tttactagcc tcaaaccaac tgcatctcct tctgaaatga tagagacatt
     4381 cccacggtct atcacatcta gcaaggtagc ttgaataagt tgatcaaagg tgaattttcc
     4441 agctcccttg accaagggac tcacttcctc caaggaggtc gagtagactg cttctgataa
     4501 aaccataggc tctaattcca ttggtggttc atagagacga tgatttttgg catatttgac
     4561 tgaaggagtg gtctttcttc tataaataaa atagaagcag acactcaata acaaggagat
     4621 agaaagtatc gaagggagga cccaagtaac gagttgttta ctctgatctt tttctctaac
     4681 aatcgagtct tctatcttat taaactcttc taaacgattc cctttcaatc cctgatccct
     4741 agcgctagca aaatcggtcc gaggccaata ggcatgcaac tcaactccac gcttagccgg
     4801 aagattgtct aaacggatag tataatcaag gttactcttt tcaatcgttc cctctctaaa
     4861 aagtttccct gtatggaaaa agagtttttc agcccccttg tctcccctta catgaaattc
     4921 aaacttttca atagactctg aactatctgt cagaggttgc caatttaatt cagcgatatc
     4981 atcataaagg aaaagtaaat tttttaagtt ccagacgagg tcaacttcaa ctatgtcgcc
     5041 ctcctgacct ggattataga ctctcacagt ataaccatcc gcttcttctg ttacttcgct
     5101 agtcacatct gctagttctg caccgttttt cgcggcctga acctttggat gagggtcaat
     5161 gtcaaacccg ctaggcatct taccagcacg tccaagtccc acgatttgtc ccttaaagtc
     5221 ctcctcaaac tggtaaacta tcttctgtct aaactctgcc gtattatctg catgaatata
     5281 caaatcccct tgataagagt ttatcttgaa atcaatggca aaaacagaga gtggaagaag
     5341 gcaaaacaag cctaacacca gtaagaaaaa agtttttttc atcaactaag cccccttttt
     5401 atctttctta tcattatagc attttttcgt aagtaaaggc ttacttatgt tgaaaaatta
     5461 cgcatttttc gataaaatag gagacagtta ttttttaata gatcagaata ggagaaatca
     5521 tgagaaaaat atacttatct attttcacaa gtctcttgct gatgctagga cttgtcaatg
     5581 ttgctcaagc cgatgaatat ttacgcatcg ggatggaagc agcatatgct ccctttaact
     5641 ggacccagga tgatgatagc aacggagctg tcaaaatcga tgggaccaat cagtatgcca
     5701 acggatacga tgttcaaatc gccaagaaaa tcgctaagga cttaggtaaa gaacctttgg
     5761 ttgttaaaac caagtgggaa ggtctagtcc ctgcccttac ttctggtaag attgacatga
     5821 ttatcgcagg tatgagtcca actgcagaac gcaaacaaga aattgccttt tcgagcagtt
     5881 actacactag cgaaccagtt ttgcttgtca aaaaagattc tgcctacgca agtgctaaat
     5941 ctttggatga ctttaacggt gcaaaaatca cttctcaaca aggggtctac ctctacgact
     6001 tgattgcaca aatcccaggt gctaaaaaag aaacagccat gggagacttc gctcaaatgc
     6061 gacaagctct tgaggctggt gtcattgatg cttatgtttc tgaacgtcca gaagcactga
     6121 ctgctgaagc tgcgaactct aagttcaaga tgattcaagt agaacctggt ttcaaaactg
     6181 gggaagaaga tacagctatc gctatcgggc ttcgtaaaaa tgacaatcgt attagccaaa
     6241 tcaatgccag cattgaaacc atttcaaagg acgaccaagt tgccctgatg gatcgtatga
     6301 tcaaggaaca acctgccgaa gctacaacaa ctgaagagac tagcagtagt ttctttagcc
     6361 aagtcgctaa aattctttct gaaaactggc aacaactctt gcgtggtgct ggtatcactc
     6421 ttttaatctc tatcgtcgga accatcatag gtctcattat tggacttgcc attggtgtct
     6481 tccgtactgc tcctctctct gaaaacaaag ccatttatgg ccttcaaaaa ctagtcggct
     6541 gggttctcaa tgtctacatt gaaattttcc gtggtacgcc aatgattgtt caatcgatgg
     6601 ttatctacta tggaactgcc caagctttcg ggatcaacct tgaccgtaca ctggctgcta
     6661 tcttcatcgt ttcaatcaat accggtgcct acatgactga aatcgtccgt ggtggtatcc
     6721 tagcagttga caagggacaa tttgaagctg cgactgctct tggtatgacc cataaccaga
     6781 ccatgcgtaa gattgtccta cctcaggtag tccgtaacat cctacctgca actggtaatg
     6841 aatttgtcat caatatcaaa gatacatctg tattgaacgt tatctctgtt gtcgaacttt
     6901 atttctcagg aaataccgtg gcaacacaaa cctatcaata cttccagaca tttacaatca
     6961 tcgccgtgat ttactttgtc ctcaccttca ccgtaacacg tatcctacgc tttatcgagc
     7021 gcagaatgga catggatacc tacactacag gtgctaacca aatgcaaacg gaggatttga
     7081 aataatgaca caagcaatcc ttgaaattaa acacctcaaa aaatcctatg gacaaaacga
     7141 agtgctaaaa gacatttctc tcactgtcca caagggagaa gttatttcta tcatcggaag
     7201 ctctggaagt gggaaatcaa ccttcctacg ctccattaac ctacttgaaa cgccaactga
     7261 tggacaaatc ctttatcatg gacaaaacgt cctcgaaaaa ggctatgacc tcacgcaata
     7321 ccgtgaaaag ttagggatgg ttttccaatc ctttaacctc tttgaaaatc tcaacgttct
     7381 tgaaaacaca atcgtcgctc agacaactgt ccttaaacgc gaacgcacag aagctgaaga
     7441 aattgccaaa gaaaacctgg aaaaggtcgg catgggagaa cgctactggc aagctaaacc
     7501 caaacaactc tcaggtggtc aaaaacaacg tgtggccatt gctcgtgccc tttcaatgaa
     7561 tcctgacgcc attctctttg atgaaccaac atcagctctc gatccagaaa tggttggaga
     7621 ggtcctcaaa atcatgcaag atctggctca ggaaggcttg accatgattg tcgtaaccca
     7681 tgaaatggaa tttgcccgtg atgtctctca ccgtgttatc tttatggata agggcgtgat
     7741 cgctgaagaa ggtaaaccag aagacctctt caccaatcct aaagaagacc gaacaaaaga
     7801 atttcttcaa cgttatctca
//
LOCUS       DBERPV010000056         6908 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.56, whole genome shotgun sequence.
ACCESSION   DBERPV010000056 DBERPV010000000
VERSION     DBERPV010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6908
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.56"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(112..387)
                     /locus_tag="ACL8C7_001923"
     CDS             complement(112..387)
                     /locus_tag="ACL8C7_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HGS1396062.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(494..1333)
                     /locus_tag="ACL8C7_001924"
     CDS             complement(494..1333)
                     /locus_tag="ACL8C7_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGS1396063.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGHILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRAVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1475..2323
                     /locus_tag="ACL8C7_001925"
     CDS             1475..2323
                     /locus_tag="ACL8C7_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGS1396064.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2416..3333)
                     /locus_tag="ACL8C7_001926"
     CDS             complement(2416..3333)
                     /locus_tag="ACL8C7_001926"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HGS1396065.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3813..3961
                     /locus_tag="ACL8C7_001927"
                     /pseudo
     CDS             3813..3961
                     /locus_tag="ACL8C7_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
     gene            complement(4181..4474)
                     /gene="rpmA"
                     /locus_tag="ACL8C7_001928"
     CDS             complement(4181..4474)
                     /gene="rpmA"
                     /locus_tag="ACL8C7_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HGS1396066.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4491..4835)
                     /locus_tag="ACL8C7_001929"
     CDS             complement(4491..4835)
                     /locus_tag="ACL8C7_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HGS1396067.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(4851..5165)
                     /gene="rplU"
                     /locus_tag="ACL8C7_001930"
     CDS             complement(4851..5165)
                     /gene="rplU"
                     /locus_tag="ACL8C7_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HGS1396068.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5201..5288)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5353..6051)
                     /locus_tag="ACL8C7_001931"
     CDS             complement(5353..6051)
                     /locus_tag="ACL8C7_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HGS1396069.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKA"
     gene            6453..6752
                     /locus_tag="ACL8C7_001932"
     CDS             6453..6752
                     /locus_tag="ACL8C7_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HGS1396070.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT         2178 a         1404 c         1143 g         2183 t
ORIGIN      
        1 aatattttcg gaacattcaa ctttttaact ctatttatta ctaaatttca taattaaaaa
       61 gcctactgac caagctagaa agcttgatac aataggcttt ttaaagactg attatttaac
      121 agcgtcttta agagctttac cagctttgaa tgctggtact ttagaagctg caattgtcat
      181 ttctttacca gtttgtgggt tgcgaccttt acgttctgcg cgctcacgaa cttcaaagtt
      241 accaaaaccg atcaactgaa ctttttcacc agctgcaaga tagtcagcta ctgctgcaaa
      301 tacagcttca actgctgctg ctgagtcttt cttagtcaat tctgtagctt ctgctacttt
      361 agcgatcaaa tcttgtttgt ttgccatgtt aatgattcct ccaaataatt tctaattaac
      421 aaatataatc atatcctaaa atccctttta ggtcaagtta aaaacgctat ttcttcccat
      481 tttatttatt tttttaggag tggtaacgta tcaaaatagc ccaagcgttc tcacccgtgt
      541 gagtttgaat aatggaaccc gtttccaaaa cagaaattgg cttttcaaca taagcttgta
      601 agctttcttt catctctttt gcccaatcat cactaccaga atatgaaatt ccaatctctg
      661 ctacagcacg ttcagaaagc gatgttatca actcatctaa ccatttttta aatgttttag
      721 ttccacgacc tttaaccatt ggctgcaatt catggtcttt catttgcatg acagcacgga
      781 tattgagaag agagctcaac aagccagtta cacggctaat tcgtccacct ttgacaagat
      841 tttccaaagt tgaaacacca atataaagct ctgtatggtt tttaacctct tctacatgag
      901 ataaaattgc ctccatatct ttaccttctt gagctaactt cgcagcctca acaacttgga
      961 atttcagggc ttggtcagtg aaggaactat caacaacagt cacatctgca gtagataggc
     1021 tagcaccttg gcgtgctgct tctaccgtac ccgaaagagc atgggacata tgaatagcaa
     1081 gaatatggcc accatctttg cataggtctt caaaaatctc agcaaagaca cctacaggtg
     1141 gctgacttgt tttcggaaga ttcttacttt cttgcatcaa ctgaagaaat ttaccttctt
     1201 ctttcaaatc cgcatcagaa taaacaacat tatcaatcat tacagataat ggaacaattg
     1261 taatatctaa ttgctttact agttcaggtt caatagtaac agatgaatcg gttacaatct
     1321 taatttttgt catagtatca atctttctat tttaggattc agattggttt ccttacttct
     1381 aattatatca aaaaaaagat taaaaatcct aatggagtca atcaaatttt ccgtaaaatt
     1441 tgatataatc aacttataag aaaagaggtg tcctatgatt aaaaaaattt accccatttt
     1501 taccatttta ctaggtgctg ctatttatgc ttttggactg acttattttg tagttcccca
     1561 tcatctcttt gaaggagggg cgacaggcat taccctcatc accttttatc tttttaaaat
     1621 ccctgtttcc ctcatgaacc tgctgattaa tattcccctt ttcatcctag cttggaagat
     1681 ttttggagcc aaatccctct attctagttt actaggaacc ttagctttgt ccggctggtt
     1741 agcttttttt gagcatattc cccttcatat tgatcttcaa ggtgatttac taatcacagc
     1801 ccttatagcg ggaatcctat tgggaattgg ccttggaatt atttttaatg ctggaggtac
     1861 aactggcgga actgatattc tagctcgtat tctcaacaaa tacactcata tatccatagg
     1921 aaaactgctc tttatcttag atttttgtat tctcatgttg attctcctaa tcttcaagga
     1981 tttgagattg gtttcctaca cgcttttgtt tgattttatt gtttctcgtg ttattgattt
     2041 gattggtgaa ggaggatatg ccggcaaagg ctttatgatt atcacaaaac gtcctgacca
     2101 acttgctaag gcgattaatg atgacctcgg aagaggtgtt acttttattt ctggtcaagg
     2161 ctactatagt aaagaaaatt tgaaaatcat ctactgtatt gtcggaagaa atgaaattgt
     2221 gaaaacgaag gaaatgattc atcgaatcga tcctcaagcc tttataacta ttacagaagc
     2281 ccatgaaatc ctaggagaag gcttcacctt tgaaaaagaa taaaaagagg taatgtcgtg
     2341 acctcaaaag ttagactaaa tcatctatct tttgggttac agacaacctc ttttttattt
     2401 tatttactca agctcttaag accaattccg agttacttct tcatcagcct ttaactgatc
     2461 cactaattgg tcaactgagt caaatttggt catatcacga atgcgatcaa gccaataaac
     2521 catgacggtt tccccataaa tatcttgatt aaaatcaaaa atattgactt caaaacgtgc
     2581 ttcttctcca tcaaaggtca catttttccc gacactagcc atagcacgat acttctgtct
     2641 ttgaatctca acatcaacga cataaacgcc atctgctggc atataagtac ggtctaaaag
     2701 cactaaattc gctgtcggat aaccaattgt acgaccacga gcattaccat gaaccaccat
     2761 acctcttgat ggaagcggtg cccccaaaag ttttcctgct tctttcacat ttccatctaa
     2821 aatagcttga cggatacgag ttgaactaat ctttcctttc tcatcttcta caggtggaac
     2881 aatgataact tctccatcaa agtaatcctt taaatcttct gctgtttttt tgtcagaacc
     2941 aaatgtataa tcaaaacctg caacaataat tttggcattc atagccttga tataagttgc
     3001 aaagaattct tgtgcagtga gactagcgaa ttgactacta aaatcaagga gatataattc
     3061 ttctacacct tcgcgcttta attttctttc acgttcagca gggttcaaaa tatgcaaaaa
     3121 caaatctgga tgataaggct ctaaagcgat ctttggagat tcattaaagg tcataacgac
     3181 gataggtaat aaatcctttc tcgcagcctt gttggcaaca cgaaataatt cttgatgccc
     3241 cttatgtatg ccatcaaaat agccgagaac aacgactgaa tcagatggtg tgccaatatc
     3301 tttttggttt tttataggaa tagtaataat cataaaataa ttatatcata gcgatagcta
     3361 tttctggaac agaaaatctg aaatgttgtt tttttcacat gaagtgtacc tgttttcaaa
     3421 aagcacttta ttctatcgtt gcttaactat gaactttgca atattcttct caaaaacttg
     3481 taggacatct tcaaaatttt gcaaggagtg attagacttg ttcggtaacc ataaagtgtc
     3541 atactatgct tatgtatgaa aaagcaatgc aactaactcc tgagaacttt aaattactaa
     3601 ttggtgccga aaaggtagaa tttagaatcg aggtacacct atggctgtaa aatttacaaa
     3661 atgagacaac ttgggcaaga tgtttgaaga atttcctaaa ctccctgatt tgaagcaagt
     3721 cactttccct gatgacaaag aaaaaagcca aaacagcaaa gaaaaactag atgactgctt
     3781 tccaacaact cccatctagt gtgcttcaga ctgggctatt tttctctcca tctgttagct
     3841 tggattctca gacagtttca gctaaagaat atcttttccc ttatcagaag gaacggctca
     3901 aaccattcag acaagtgaag ggacgacaag ccaatatttg aaaccagata gcagttctta
     3961 tagtcaattg aaataaaatc tgaagaaatc gagtaggaaa ctcatatcaa tttttaacag
     4021 tgttctattc cagattcaat ccactataca tattaaaaag tatgggtacc aaaacaaaaa
     4081 aacaggctct ccgaaaactc ggaaagcctt attttaagct gtttctagct tcctcacctt
     4141 tacatttcaa ggttcgggat aaaaggttca atggaccttt ttatttagcg attgggtaaa
     4201 cagaaacttg ttttttatcg cgtcctttac gttcaaagcg tactacgcct tcaactttag
     4261 cgaacaaagt atcgtctcca ccacgaccaa cgtttacacc tggatagatg tgtgtaccac
     4321 gttgacggta aaggattgat ccacctgtta cagtttgtcc gtcagctgct ttagctccaa
     4381 gacgttttgc ttgtgaatca cgtccgtttg atgtagaacc tccacctttt ttgtgggcga
     4441 aaagttgcaa gttgttaaga gtcattttta acataatgtt ttcctccgtg ttagttttct
     4501 gtgataactc tggtttggac gaactcagaa tagttctccg ataagtttgc catacctaag
     4561 aaaaatgatt caaagaataa ctgggtcatt tctctctggt gtgaaggaag atcttttggt
     4621 atttcaacca tcagatagcc accttcatct tcgtttaatt ctaggattgg ttcatagcct
     4681 gcaaatttct caatagaatt gataaagtta atggcaagcg tagaaaccga tgcacacacg
     4741 acatctaagc cgtattcgcc actctcggcg tgtccagtaa tttccgcact cctcagctcg
     4801 ccatcttcgg ctctctcaaa gactgcctgt atcatgtgtt ctccttaaaa ttaagcgttg
     4861 attgcgttga tgacaacttt tgtatatggt tgacggtgac cttgtttacg gtggctacct
     4921 tttttaggtt tgtacttgta agtaaccact ttcttttgtt ttccttgttt ttcaacagtt
     4981 ccaactacag tagctccagc aacaagtgga gttccgacaa cagtgttttc accaccaaca
     5041 agaacaactt cgttaaaagt aacttcttga ccagcttcaa cgttcaattt ttcaacgtaa
     5101 actgcttgac caacttcaac tttaacttgt tttccgccag ttttgataat tgcgtatgtg
     5161 ctcattatgc acctcctatg atttttatgg gtttccccga ttttttgtga agactcgcct
     5221 agcatcgtgg gacgaaccac ttaaacttga ataatcaagc aacgatgttc gtgcggttgc
     5281 acaggatcgt gcatagtcaa ctcttcaagt atagcatatc tcctattttc ttacaagtaa
     5341 taacacctaa aatcaagctt tttcttttac ttttttctgc caagaggcaa aaagcatgct
     5401 gaggtaaaaa acgctcatca taataggaac accaagaatg gtcttttcat gatagaaaat
     5461 cgtcaaatag gctgaaaaga caacgccaag gacaaaacta ctaagcaggc taacaaatat
     5521 gaatccttca cgcaaaaaag gagtgtgctt ggttcggaaa taatctccaa aagccagcat
     5581 ggtccgtttg atattccctg tcataaaagc gttattatag gcaatacccg acacttctcc
     5641 aaaagcagtt gtcaccagtc ccatacagaa ggccaagggc ggcactagat agatattatc
     5701 cacagtttgc ggcacaaaag caataatgat tgataagatt gccaagggaa tcaaggacag
     5761 aataggtttt ttcacaattc tcaatttttc cttataaatc gttaataaaa agactcccat
     5821 cataaacgct agcaaggtga gaaccttgtc cctaacatcc gaaacattat ttttaattaa
     5881 ttctactgaa agaaagacaa catttccagt ttgtccagct acaagggtat tcccgcgaac
     5941 aataaaagtg taagcatcca catatccagc acaaaacgtc aaaaaaagtg ctaacctttt
     6001 agactgacgt gatatttttc ttataggtaa taacctcatt ttacctccca ttgtattttc
     6061 tcttagaaat attgtaccat tttctttcta aaaaatcgta ggctaccatt tagattttac
     6121 tattagcata aaaataataa tagacaacta tttatccaaa aatagataga tgtaacatgt
     6181 ttgcaaacaa agcatacgaa cctttagtaa aatcatttcc atgaaactag aatagagccc
     6241 tcttagcaaa aatcattatt ttaatttatt tctaatcact ccttgacata aataactctc
     6301 accaataaaa gactatgtct taaaaaaatg gtataataaa atcaatactt gggcttgatg
     6361 gctatgctac taataacaat taggagagaa aatcaggcac ttgttaacaa caaggattat
     6421 ccccttgaga tgaaaggaac tttagaaatc ttatgatgaa catgcaaaac atgatgcgtc
     6481 aagcacaaaa acttcaaaaa caaatggaac aaagccaagc tgaacttgct gctatgcaat
     6541 ttgttggcaa atctgctcaa gatcttgtcc aagcgacctt aactggcgat aagaaagttg
     6601 tcagcattga tttcaatcca gctgtcgttg acccagagga ccttgagact ctttctgata
     6661 tgaccgttca agccatcaac tctgctcttg aacaaatcga tgaaactacc aagaaaaaac
     6721 tgggtgcttt cgctgggaaa ttacctttct aaaaacaagg agctagaaca atgcttgtcg
     6781 ataacaaagg ctaagaaagg tgcaaaaatg actctataat atttgtagtg ggtaaatccc
     6841 ctatggatat tatggagctt atttttgtgt agaaaaaaag tcccatatga cctataatga
     6901 aaagcgac
//
LOCUS       DBERPV010000057         6720 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.57, whole genome shotgun sequence.
ACCESSION   DBERPV010000057 DBERPV010000000
VERSION     DBERPV010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6720
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.57"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..265)
                     /locus_tag="ACL8C7_001933"
     CDS             complement(<1..265)
                     /locus_tag="ACL8C7_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HGS1396071.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDFLMATLQYVREYRTYEQIAADFGIHESNLLRRSQW"
     gene            complement(319..420)
                     /locus_tag="ACL8C7_001934"
                     /pseudo
     CDS             complement(319..420)
                     /locus_tag="ACL8C7_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase"
     gene            complement(645..1505)
                     /locus_tag="ACL8C7_001935"
     CDS             complement(645..1505)
                     /locus_tag="ACL8C7_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HGS1396072.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            complement(1521..2798)
                     /gene="spxR"
                     /locus_tag="ACL8C7_001936"
     CDS             complement(1521..2798)
                     /gene="spxR"
                     /locus_tag="ACL8C7_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS-HotDog domain-containing transcription
                     factor SpxR"
                     /protein_id="HGS1396073.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            complement(2791..3342)
                     /locus_tag="ACL8C7_001937"
     CDS             complement(2791..3342)
                     /locus_tag="ACL8C7_001937"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1396074.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            complement(3358..4617)
                     /locus_tag="ACL8C7_001938"
     CDS             complement(3358..4617)
                     /locus_tag="ACL8C7_001938"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGS1396075.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            5886..6720
                     /locus_tag="ACL8C7_001939"
                     /pseudo
     CDS             5886..6720
                     /locus_tag="ACL8C7_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2056 a         1504 c         1102 g         2058 t
ORIGIN      
        1 cccattggct ccgacggagt aagttgcttt cgtggatacc aaaatcagcc gcaatttgtt
       61 cataagttcg atattctcgc acatattgaa gagtggccat aagaaagtct tccaggctta
      121 atttaggttt tcgtccacct tttgcgtgtt taagttgata agctgttttt aatacagcta
      181 acatctcttc aaaagtggta cgctgaacac caacaagacg cttaaatcgt gcatcagtta
      241 gttgtttact tgcttcatca ttcatagaac tactatacca tattttgttt cgcagggagt
      301 ctaatataaa aaaataaatt taagattggc aatacgaacg ttaaacagaa ttccatttct
      361 ctttttagaa tcaaaacgac aatattgtgg aatctctaca ggaacaatag actgcgacac
      421 taaaatatcc tcccttagtt ttactttact aatagtatat aggaggagag ccctgaatcc
      481 tagacccttt gttatgatgc gcttacaaac agagttggaa aaaatcttaa aagcagaaaa
      541 acgcatgata tcagccccta acacttgata caatgcgttt tattatgaaa aaatctactg
      601 gattttttat caaaataaac ttccagtagt cttttcactt tttattaata agttccttct
      661 tcaccttggc tagtcaagat aacaggtcca tctttcgtaa tgacaaattg gtgttcatac
      721 tgacatgaca atccaccgtc aatggtctta tgcgcccaac cagttttcat atctgtatca
      781 atttcccaat cgcctgtatt gatcattggt tcaatggtta agaccattcc ttcacgaaga
      841 cggagtccac gacctgcaat accatagtta ggaaccattg gttcttcgtg catagttggg
      901 ccaacaccat gaccaaccaa atcacgcact acaccgtaac cacgactttc agcgtattct
      961 tgaatagccg caccgatatc accgatacga tttccaacaa cagcttgctc aatacccttg
     1021 tacatagctt ctttggttac atccatcaag tttttgactt cttcggacgg tgtaccaaca
     1081 gcataagccc aacatgagtc tgctaaacca ccagaatagc tctgagtgta ttttttcatt
     1141 tgttcaacat tgttgaagtt taattttgag acatttaggt cagatttagc aatgggacct
     1201 cccaaaacca tatcaacttt gagcaaatca ccatctttca agatataatg acgagggaaa
     1261 gcgtgagcca cttcatcgtt aagagagcaa caggtagcat aaggatagtc catcatggca
     1321 ccgtcaaccc caatctgaag tggaaggaaa ttttcttctt tacaacgacg gcggacatat
     1381 tcttcaactt cccacatatc tacgcctggc ttaatcaaat cacgtaagcc tatatgaata
     1441 cttgctagaa aatcaccagc cttgtccata gcttcgattt cacgagctga ttttaatgtt
     1501 atcatctttt ctcctagttt ctaattaatt ttaacagtca catttgcttt tgaaacaatc
     1561 tggtgaccat gataaatatc gtaatcaatt atagctgacc gtctcgtatg atgaataatc
     1621 cgtgcctgaa tgcgcaatat atcatctatc tgaacagcct gcaaaaagta gatcagcatc
     1681 tgctcgataa tgagattgcg accactatta acaactaaat cttgggtcat gtgggtcaga
     1741 atttctgcca atacaccatt agccaaaact ccattttttt ctagcataaa gggttccact
     1801 gtaatgacta cttcatcatg gtgataagag agcttttgtc caatctgctc agaaaaagtt
     1861 ggtagagccg aaacttggga acggctcatc ttctccatga catctcgtcg cgtcacaacg
     1921 ccaagcaaag tttgattgct tcgaacaact ggtaccattt caaagtcttc tgcgatcatc
     1981 cgttgactca cattggcaat atttgtcgat aacccaacca aaaatagact acgagacata
     2041 accttatcaa ttgtcgtgct tggtgattta tcaccagcgt ctctcatggt tacaacgcca
     2101 acaacgacct gatgttgatt gataacaggg aaacggctgc tacgattctt acgaaccaag
     2161 tccaaataat ctttaactgt atctgtctct ctcagaaaac catactcatg actagggcga
     2221 taaagtttct caactgtcag aatatcagtc ttgatttgga catttgacaa ggctttattg
     2281 atcatggtcg cgacggtaaa ggtatcatgc ttacttctta gaacaggaat ccctttttga
     2341 ttggccagtt taagcacatc atcatgaacc tgaaatcccc ctgtaaccag aactgcattt
     2401 tcattttcca aggctagcaa ctgaatacgg gttcggtctc cgacaatcaa gagcccccca
     2461 tcatgaaggt aagacaagat attttgttca gtcatggcac caattgaaaa cttactaaac
     2521 tctctctcta aaccttcttg cccagccaga acctcagaag aagtcacttc tgcaatttca
     2581 gcaaacgtta atctctctat agcaactttc tgggatttaa cacgaattgt tccacttcta
     2641 ggacgggtct ccacaattcc acggttttca gcttctttaa tagcccgata ggctgttcca
     2701 tcactaactc ctagatgatt cgaaatgcta cgaacactga cccttttacc tactggtaat
     2761 tcctccaaat agcttagaat ttcctgatgc ttactcattg aactctcctt ttacataccg
     2821 aaattcaaga taatcccgca tttttcttgt gtaacgatca cttcccttaa actgacggaa
     2881 caaactaaat ccagacttaa gagcaactct ttggctagct tcattttcaa ggtgggtaat
     2941 gatagataat tgttttaagc caaattcctc aaaagaaagc tgacaaattt ttctaacaac
     3001 ctctgtcata aatccttgcg accaagcatc ttttctcaaa aaatagccaa gctcagcttc
     3061 ttttttgatt tcatctaact tctcaaattt aatagaacca atcatttgtt gatttttctg
     3121 gtcacaaatt gcccacactc ccaaagggga cttcataaag taattggcca gtgcatattg
     3181 actttcttcc agacttgcct gcgttgggaa aataaattga agattttctg gatttgaagc
     3241 tatctcgcgg aagtcctgac tatcactaaa aaagaaagga cgcaaataca agcgatccgt
     3301 ttcaaaaaaa gaaaacattg ctaatttggt ccaaatattc ataaacacct ctacggttta
     3361 atcctcaaca agtctaatat ccgctcctaa attacgtaat ttttcgataa tatcagaata
     3421 accacgtaag ataaactcga tattggtaat ttcagttttg ccttcagcca taagcccagc
     3481 aatgactagt gcagccccag ctcttaagtc ggtcgcttta acactggccc cacgtaaatc
     3541 acgtccaccc gtgtacaaaa tatgaccatt tgttgtcgaa atatccgcat ccatctttgc
     3601 tagttcaaaa acatgattta cacgtttttc gtaaatcgta tcgacaattg taccacgacc
     3661 attcgctctt agtaaaagag gggtaagcgg ttgttgcaaa tcagttgcaa agcctgggta
     3721 aggagctgtc ttaatattga ttgctttcaa attagactgt tcctcgacaa aaatgctgtc
     3781 ttcagataca gtcattctca ctcccatttc ttccaactta gcaataaacc cttccaggtg
     3841 ttcgtaaaga acattattta tacgaattcc tttaccaact gcagcagcta aagatatata
     3901 tgttccagct tcaatgcggt ctggaatcac ctgatgacgt gtcccatgta atctttcaac
     3961 accatcaata atgatgatat tagttcctgc cccacggata tgggcaccca tattattcaa
     4021 gagagtagct acatcaataa tctcaggttc acgggctgca ttttcaataa tagtacgacc
     4081 atttgcttta accgcagcaa tcatcgtatt aatcgttgct cccacactaa ccgtatccat
     4141 gtaaatactt gcaccatgaa gtcctgtatc tttagcagat aacttcatgt tatctccctc
     4201 gtagctagca gtggcaccca tagcttcaaa cgccttaagg tgtaagtcaa tcggacgagg
     4261 accaagatca catcctcccg gtagaccaac tgtcgcttca ccaaaacggc ctaagaggct
     4321 cccataaaaa tagtaagatg cacgaagact gttaatttta ccataaggca ttggaatatt
     4381 ttgaacacct cttgggtcaa tctccaatac atcgtcataa cgcttaacag tagctcccat
     4441 caattccatg atttcgacaa gactggctac atccgaaata tctggaacgc aatccaaagt
     4501 caccacatca tcagccaaga taatagctgg aattaaggca acgacactat ttttagcacc
     4561 actaatagtg atttcacctt gcagtggtaa tccaccattg ataacaattt ttctcattct
     4621 aagttttcaa tactctttca agatttctaa taaggtcttc aaaataaagt atatcataaa
     4681 tttatccttt tttccatcct tttcaatttt attggataaa tcagagttga cgagttagta
     4741 actgaattac taatactcaa tgaaaatcaa agatcaaact aggaaactag ccgcaggttg
     4801 ctcaaaacac tgttttgagg ttgtagatgg aactgacgta gtcagtatcc tacatatacg
     4861 gcaaggcgat attgacgtga tttgaagaga ttttcgaaga gtataatctt tctcgaatcg
     4921 ctattgcccc ttttttatcc cctaaaactg agtaggatct aagactagat ctcttatcta
     4981 agtatcggaa tacggctgtt caactaaatt ttagcaagaa cttctcccct tctctcagtt
     5041 cacagaagcg ttttatacat accgtcctat cagacaatct attttaaaga taaccgtgac
     5101 tcaggatcac ttctatctgt cgttttctct ttatagtgat agacctcacg ggataagtcg
     5161 tacatctttc ctcgtgtata caagatataa ggacgttaaa aggttacagt gaaaatagaa
     5221 aatcttagta cgaattcaat tactctcgtg atttacgcat ataggttacg actacctttt
     5281 tggactttag agtttgagac ccccttatcc gctatatacg ccttactatc acgttcctgt
     5341 tcgtaaagcc acgatttcgc tatcccttcc tctgacgatt cttatttcca gcgtcagact
     5401 taaaacggtc tatccccaga ccgttttaat ccactacctc acgatagtca ggcttgggaa
     5461 tcgctatttg actcgccgag aactttgaca tcagatatac tataacaaat tgaaataaga
     5521 atcaaacaat ttaattttga aattcaaatc aatttataac aatatagttg attgaaacta
     5581 gactagtaca cctctgcttc taaaacattg ttagaaatcg attttactgt cctgatcgat
     5641 ttgttctgtt ctcatttcat tttactatat tttagaagat atgctgtgct attccagatt
     5701 cagttcgcta tacatgcccg tcgtaccaca aaatcccgtg tttgatgtgg cacgggattt
     5761 ttggctctat aatatttgta gtgggtaaat ccactataga tattatggag cctatttttg
     5821 tgtagaaaaa aagtcccata tgacctataa tgaaaagcga caaaaccatc attagaaaaa
     5881 ttcatatgga acaattacat tttatcacaa aactgctcga tattaaagac ccaaacatca
     5941 agattctaga tatcatcaat atggataccc acaaagaaat tatcgctaag ctggattatg
     6001 aggctccatc ttgccctgat tgtggaagtc taatgaagaa atatgacttt caaaaacctt
     6061 ctaaaattcc ttatcttgaa acgactggta cgccttctag aattctcctt agaaagcgtc
     6121 gtttcaagtg ctatcactgt tcaaaaatga tggttgctga gactcccctg gtaaagaaaa
     6181 atcaccaaat ccctcgtatt atcaaccaaa agattgctca aaagttaatt gaaaaaattt
     6241 ctatgactga tattgcccat cagctggcca tttcaacttc aactgtcatt cgcaagctca
     6301 atgactttca ctttgagcat gatttttctc ggcttccaaa gattatgtct tgggatgagt
     6361 atgccttcac taagggaaag atgagtttca ttgcgcaaga ttttgataat cttaatatta
     6421 tcactgttct tgaaggcaga acacaagctg tcatccgaaa tcactttctt cgctacgata
     6481 gagccgtccg atgtcgcgtc aaaatcatta cgatggatat gtttagccct tactatgact
     6541 tggctaaaca gcttcgcttt caaatttcta ggctcaggct gaaacagtct cccaggctgt
     6601 ttcactcccg aatgctaaaa tcgttcttga tcgctttcat attgtacaac atcttagccg
     6661 tgctatgagt cgtgtgcgtg ttcaaatcat gaatcagttt catcgaaaat cccatgaata
//
LOCUS       DBERPV010000058         6705 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.58, whole genome shotgun sequence.
ACCESSION   DBERPV010000058 DBERPV010000000
VERSION     DBERPV010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6705
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.58"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..296
                     /locus_tag="ACL8C7_001940"
                     /pseudo
     CDS             1..296
                     /locus_tag="ACL8C7_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            357..1319
                     /locus_tag="ACL8C7_001941"
     CDS             357..1319
                     /locus_tag="ACL8C7_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGS1396076.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYEDTSISVSSNETDKV
                     LAGSLYTDTNEQGLMIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAEASKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRGVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            1496..2503
                     /gene="gap"
                     /locus_tag="ACL8C7_001942"
     CDS             1496..2503
                     /gene="gap"
                     /locus_tag="ACL8C7_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HGS1396077.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2571..3446)
                     /locus_tag="ACL8C7_001943"
     CDS             complement(2571..3446)
                     /locus_tag="ACL8C7_001943"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGS1396078.1"
                     /translation="MQFTFTLPASLPQMTVKQLLEEQLLIPRKIRHFLRIKKHILINQ
                     EEVRWNEIVNPGDVCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTH
                     GNQPNEIALLNHVSTYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISR
                     EYWALVDGNINRKELVFRDKIGRDRHDRRKRIVDAKNGKYAETHVSRLKQFSNKTSLA
                     HCKLKTGRTHQIRVHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTF
                     TTLSNTFEKELKKNG"
     gene            3533..5728
                     /gene="pbp2a"
                     /locus_tag="ACL8C7_001944"
     CDS             3533..5728
                     /gene="pbp2a"
                     /locus_tag="ACL8C7_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP2A"
                     /protein_id="HGS1396079.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRHFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQSLAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5781..5933
                     /gene="rpmG"
                     /locus_tag="ACL8C7_001945"
     CDS             5781..5933
                     /gene="rpmG"
                     /locus_tag="ACL8C7_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGS1396080.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            5943..6119
                     /gene="secE"
                     /locus_tag="ACL8C7_001946"
     CDS             5943..6119
                     /gene="secE"
                     /locus_tag="ACL8C7_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HGS1396081.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6174..>6705
                     /gene="nusG"
                     /locus_tag="ACL8C7_001947"
     CDS             6174..>6705
                     /gene="nusG"
                     /locus_tag="ACL8C7_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HGS1396082.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAE"
BASE COUNT         2080 a         1179 c         1446 g         2000 t
ORIGIN      
        1 acttacgaag agacgatgac gagcgacttt tttgaagtat ggtttcagaa gtttctctta
       61 ccaacattaa ccacaccatc ggttattatt atggataatg caagattcca tagaatgggg
      121 aagctagaac ttttatgcga aaagtttggc ataaactttt acctcttcct ccctactcac
      181 ctgagtacaa tcctattgag aaaacatggg ctcatatcaa aaagcacctc aaaaaggtat
      241 taccaagttg caataccttt tatgaggctc ttttgtcttg ttcttgtttc aattgactat
      301 agttcacgga tacagttggg aaagaagcta ttaattattt ggagagtcct tttgggatga
      361 acatgtcaaa tattactata gatgggcaag aaatggatct gagtcaaacg atgccttctt
      421 atgctcaagt agtgagtctt tatgaggata caagcatctc tgttagtagt aatgagacgg
      481 acaaagtgtt ggctggatcc ctctatactg atacaaatga acagggatta atgattccaa
      541 gcagtttact aaaaaattgg aatgaacaga caggaaaaaa tttgacagct aatgatctta
      601 ttggcaaatc agtctcagcc agcattgtag aaagtgctgc cgaagctagt aagattgctc
      661 aatttcaaac gaagattgta cgtgtaatca atgatgaaga tgacatggag gacagcaaca
      721 gtttcatgct gtctcatcaa atggaaacga ttttgaaaga ggctggattt acgaaagctg
      781 tatcttattt tatcttggaa ctcaaagatc catcacagac aaaagtagta acagaagaat
      841 tacagaaaaa taagaagtat actgtgcttt ctcaacagag agttcttgat attgtgatta
      901 cctttattcg tgttattcag ggattattga ttgtgctttc atcacaagct attgtggtag
      961 cagcggttat gattggtatc attatttaca tcaatatcat gcaacgttcc aaggaaatag
     1021 gtgtcatgaa agcagttggt tatcagaatc gtggtgtcaa aggaattttt atttacgagg
     1081 ctatctggat tgtaggcatc gccttgctgc tggcattttt ggttgcacaa ggggtgggaa
     1141 gtttggcgaa tgcgattgta agtcactttt acccatccat cactaaggtt tttgaattaa
     1201 atcttttatc tgttttagga actctagttt tcgctctatt acttggttat gtctcagcct
     1261 acttcccggc gcgtaagatt agtaaaatgg atcctgtaga atcgttacgc tatgaataat
     1321 aagggattcc ttgatttaca gtcttaaaaa gaaactcaca tagaaaaaca atggccatac
     1381 ttgcaattca actcaaatag ttgtataata ggtttgttga aaggtgattt gtagtgattc
     1441 aagttactct tttcacaata aaaatttcat gattttcata aggaggaaat cactaatggt
     1501 agttaaagtt ggtattaacg gtttcggacg tatcggtcgt cttgctttcc gtcgtatcca
     1561 aaacgtagaa ggtgttgaag ttacacgcat caacgacctt acagatccag ttatgcttgc
     1621 acacttgttg aaatacgaca caactcaagg tcgtttcgac ggtactgttg aagttaaaga
     1681 aggtggattt gaagttaacg gtaaattcat caaagtttct gctgaacgtg atccagaaca
     1741 aatcgactgg gctactgacg gtgtagaaat cgttcttgaa gctactggtt tctttgctaa
     1801 gaaagaagca gctgaaaaac accttaaagg tggagctaaa aaagttgtta tcactgctcc
     1861 tggtggaaac gacgttaaaa cagttgtatt caacactaac cacgacgttc ttgacggtac
     1921 tgaaacagtt atctcaggtg cttcatgtac tacaaactgc ttggctccaa tggctaaagc
     1981 tcttcaagac aactttggtg ttgttgaagg attgatgact actatccacg cttacactgg
     2041 tgaccaaatg atccttgacg gaccacaccg tggtggtgac cttcgccgtg ctcgcgctgg
     2101 tgctgcaaac atcgttccta actcaactgg tgctgcaaaa gctatcggtc ttgtaatccc
     2161 agaattgaat ggtaaacttg atggatctgc acaacgcgtt ccaactccaa ctggatcagt
     2221 tactgaattg gtagcagttc ttgaaaagaa cgttactgtt gatgaagtga acgcagctat
     2281 gaaagcagct tcaaacgaat catacggtta cacagaagat ccaatcgtat cttcagatat
     2341 cgtaggtatg tcttacggtt cattgtttga cgcaactcaa actaaagttc ttgacgttga
     2401 cggtaaacaa ttggttaaag ttgtatcatg gtacgacaac gaaatgtcat acactgcaca
     2461 acttgttcgt actcttgaat acttcgcaaa gattgctaaa taattcttga gttgatagaa
     2521 agcaaggctt tgtggtcttg cttttttata tggaaaaatg gatgacacga tcatccattc
     2581 ttttttaatt ctttttcaaa tgtatttgaa agggtagtga aagttagcct ctctaaagta
     2641 agtgggtggg taaaggaaag tcggaaggca tgaagcataa gccggcttgt ctttgattta
     2701 ctattataga gagggtctcc caggatagga agattatgat gcaaaaggtg cacacgaatc
     2761 tgatgggttc gccctgtctt tagcttgcaa tgagccaagg aagtcttgtt tgagaattgc
     2821 tttaatctgc ttacatgcgt ttcagcatat ttcccatttt ttgcatcaac tattcttttt
     2881 ctacgatcat ggcgatcacg tccaattttg tctctgaaaa caagttcttt tctgttgata
     2941 tttccatcaa ctagagccca atattctcta gaaatctctt ttttctccaa taagcgattg
     3001 agaatgggca ggataaaagg atttttggca aagagaacta agccactggt ttccatgtcc
     3061 agacgatgaa cgacatagca ggtttggcca acataggtac tgacatggtt aagaagggca
     3121 atttcgtttg gttgattacc atgcgttttc atcccctctg gtttgtttac aataatcaag
     3181 tgttgatctt gataaacttc ctgcactaag tctgggttgc cccaagggat cgtcttttgg
     3241 ggataatctt cctcgtcaaa agtcaactgg caaacatctc caggatttac gatttcgttc
     3301 cagcggactt cttcttgatt tatcaaaata tgtttcttga ttctcaaaaa atgacggatt
     3361 tttctaggga tgaggagttg ttcctcaagt aattgcttta ccgtcatttg aggtagagag
     3421 gcgggtaatg taaatgtgaa ttgcatacag atattgtaac aaaaaaagcc ctatttggat
     3481 aggaaatagc taaattcttg tcttcctatg atgaagatga taaaataaac gcatgaaatt
     3541 agataaatta tttgagaaat ttctttctct ttttaaaaaa gaaacaagtg aactagagga
     3601 ctctgattct actatcttac gtcgctctcg tagtgatcga aaaaaattag cccaagtagg
     3661 tccgattcga aaattctggc gtcgttatca tctaacaaag attatcctta tactaggttt
     3721 gagtgcaggc ttgctagttg gaatctattt gtttgctgta gccaagtcga ccaatgtcaa
     3781 tgatttgcaa aatgccttga aaactcggac tcttattttt gaccgtgaag aaaaagaggc
     3841 tggtgccttg tctggtcaaa agggaaccta tgttgagctg actgacatca gtaaaaactt
     3901 gcagaatgct gttattgcga cagaagaccg ttctttctat aaaaatgacg ggattaacta
     3961 tggccgtttc ttcttggcta ttgtcactgc tggacgttca ggtggtggct ctaccattac
     4021 ccaacagctg gctaaaaacg cctatttatc gcaggatcaa actgttgaga gaaaagcgaa
     4081 agaatttttc cttgccttag aattaagcaa aaaatatagt aaggagcaaa ttctaaccat
     4141 gtaccttaac aacgcttatt ttggaaatgg tgtgtggggt gtagaagatg cgagtaagaa
     4201 atactttgga gtttctgcat cagaagtgag tctggatcaa gctgcgactc tggcagggat
     4261 gctcaagggg ccggaactgt ataatccctt gaattccgta gaagattcta ctaatcggcg
     4321 cgatactgtc ttgcagaata tggttgcagc aggatatatt gataaaaacc aagaaaccga
     4381 agctgctgaa gttgatatga cttcgcaatt gcacgataag tatgaaggaa aaatctcaga
     4441 ttaccgttac ccctcttatt ttgatgcggt ggttaatgaa gctgtttcca agtataatct
     4501 aacagaggaa gagattgtca ataatggcta ccgcatttac acagagctgg accaaaacta
     4561 ccaagcaaat atgcagattg tttatgaaaa cacatcgcta tttccgaggg cagaggatgg
     4621 aacgtttgct caatcaggaa gtgtagctct cgaaccgaaa acagggggag ttcgtggagt
     4681 tgtcggtcaa gttgctgaca atgataaaac tggattccgg catttcaact atgcaaccca
     4741 atcaaagcgt agtcctggtt ctacaattaa gcctttagtt gtttatacac cagcagttga
     4801 agcaggctgg gctttgaata agcagttgga taaccatacc atgcagtatg atagctataa
     4861 ggttgataac tatgcaggga tcaaaacaag tcgagaagtt cctatgtatc aatccttggc
     4921 agaatcgctt aatctacctg ctgttgccac tgttaatgat ttgggtgttg acaaggcttt
     4981 tgaggcaggc gaaaaattcg gactcaacat ggaaaaggtc gaccgtgttc ttggtgtcgc
     5041 cttgggaagc ggtgttgaaa ccaaccctct tcaaatggct caagcatacg ctgcctttgc
     5101 aaatgaaggt ttaatgcctg aagctcattt tattagtaga attgaaaatg ctagtggaca
     5161 agttattgcg agtcataaaa attcacaaaa acgggtgatt gataagtctg tagctgacaa
     5221 gatgaccagt atgatgttgg ggactttcac caacggtacc ggtattagtt catcgcctgc
     5281 agactatgtc atggcaggga aaactggaac aactgaagca gttttcaatc cggagtacac
     5341 aagtgaccag tgggtaattg gttatactcc ggatgtagtg attagccact ggcttggctt
     5401 tccgaccact gatgaaaatc actatctagc tggctctact tcaaacggtg cagctcatgt
     5461 ctttagaaac attgccaata ccattttacc ttatacgcca ggaagtacct ttacggttga
     5521 aaatgcttat aagcaaaatg gaattgcacc agccaataca aaaagacaag tacaaaccaa
     5581 tgataatagc cagacagatg ataatttgtc tgatattcga gggcgtgcgc aaagtctagt
     5641 agatgaggct agccgggcta tctcagatgc gaagattaag gaaaaggctc aaacaatatg
     5701 ggattcgata gtcaatctat ttcgctaaga tgcttgtcaa agcctagctt tcttgttata
     5761 atggataaga tggaggcgtt atggcactaa aaaaagcaag cctagcttgt gcggtttgtg
     5821 gttcgagaaa ctattcaatc aagatcagcg gaaaccccaa gcctacacga ctagaagtaa
     5881 ataaattttg taagcattgt ggcaagtaca ctacacacag agaaacgaga taggagagag
     5941 cgatgcgttt tattggagat atttttagac ttcttaaaga cacaacatgg ccaactcgca
     6001 aggaaagctg gagagatttt cgttctatca tggaatacac agctttcttt gtagtaatta
     6061 tttacatttt tgaccagttg attgtttcag gtttgattcg atttattaac attttttaga
     6121 agattagtgg agttaattac actagaaatc ttctatttat gaaaggaaat atcatggata
     6181 gttttgataa aggatggttt gttttacaaa cttattctgg ttatgaaaat aaggtgaaag
     6241 aaaatctatt acaacgtgca caaacctaca atatgttgga taatattcta cgcgttgaaa
     6301 ttccaacaca aacagtgcaa gttgaaaaaa atggaaagag aaaagaagta gaagaaaatc
     6361 gctttccagg ttatgttctt gtagaaatgg tcatgacaga tgaagcttgg tttgttgttc
     6421 gaaacacacc aaatgttaca ggatttgtcg gatcacacgg gaacagatca aaaccaactc
     6481 cattattgga acaagaaatt cgtgacattt tggtatctat gggacaaact gttcaagaat
     6541 ttgatttcga tgttgagatt ggtcaaactg tacgtattat tgatggtgct tttgcagact
     6601 acactggtaa gattacagaa attgataata acaaagtgaa aatgattatc tctatgtttg
     6661 gtaatgacac agttgcagaa gtaaacctaa accaaatcgc agaat
//
LOCUS       DBERPV010000059         6434 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.59, whole genome shotgun sequence.
ACCESSION   DBERPV010000059 DBERPV010000000
VERSION     DBERPV010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6434
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.59"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(123..419)
                     /locus_tag="ACL8C7_001948"
     CDS             complement(123..419)
                     /locus_tag="ACL8C7_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGS1396083.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPDAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLSSQGLTVTNVEGGMNAWPGQVE"
     gene            complement(409..564)
                     /locus_tag="ACL8C7_001949"
                     /pseudo
     CDS             complement(409..564)
                     /locus_tag="ACL8C7_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691454.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
     gene            641..1405
                     /locus_tag="ACL8C7_001950"
     CDS             641..1405
                     /locus_tag="ACL8C7_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HGS1396084.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGADCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            1970..3349
                     /locus_tag="ACL8C7_001951"
     CDS             1970..3349
                     /locus_tag="ACL8C7_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGS1396085.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLV
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            3363..4028
                     /locus_tag="ACL8C7_001952"
     CDS             3363..4028
                     /locus_tag="ACL8C7_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HGS1396086.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            4338..4877
                     /locus_tag="ACL8C7_001953"
     CDS             4338..4877
                     /locus_tag="ACL8C7_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGS1396087.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYKENKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YTMMHSLIYRTDLLRASQF"
     gene            4944..5354
                     /locus_tag="ACL8C7_001954"
     CDS             4944..5354
                     /locus_tag="ACL8C7_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HGS1396088.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLIDQLD
                     LSQVSHPKMREYLLNHIELTTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            5470..>6434
                     /gene="pavB"
                     /locus_tag="ACL8C7_001955"
     CDS             5470..>6434
                     /gene="pavB"
                     /locus_tag="ACL8C7_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HGS1396089.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADG
                     LNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     SPSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVQKAVADNVKDSIDVPAAYLE"
BASE COUNT         1756 a         1232 c         1478 g         1968 t
ORIGIN      
        1 atccacaacc ttaaaacagt gttttgagca gcctgcgact aacttcctag tttgcacttt
       61 aattttcatt gagtattact tcatcttctc ctgaaattga gtttttgccc agctcctctt
      121 gattattcta cttgaccggg ccaagcattc ataccacctt ctacgttggt aacggtgagg
      181 ccttgggagc tgagaaattg gcaggtagat gcagagcgga ctcctccttg acaaataaca
      241 tagtattcat ggtcaggttt gagttctttg tagccttgct ctaaggtact taatggaaga
      301 tttttggcat ctggtgcatg tcctgcttgg aattcatgtg cttcacggac atcgataagt
      361 tctagatttt cattttgata ttttccataa aagtcagcca tgctgatact agtttccata
      421 ttctactcct tctgggttag tcattttgta tagtgaataa gcgccgtcaa ggttttggac
      481 ggtaaatcct gcttgcttga ggataggctc tgcgatatag ctgcgcaaac cactgtggca
      541 gctgacgatg taggcttgtt tttctcctca gttcatcagc ttcctccttg acactttgtc
      601 agattttgat acaatagtac aaaattagag gaggcaggct atgattcaga aacatgcgat
      661 tcctatttta gagtttgatg acaatcctca ggcggttatc atgcccaatc acgaggggct
      721 ggacttgcag ttgccaaaga agtgtgttta tgcattttta ggtgaggaga ttgaccgcta
      781 tgcaagggaa gtaggggcgg attgtgtcgg cgaattcgtt tctgctacca agacctatcc
      841 agtctatgtc atcaactaca agggtgagga ggtctgtctg gctcaggctc ctgttggctc
      901 cgctccagca gcccagttta tggattggtt gattggctat ggtgtggagc agattatctc
      961 tactgggacc tgtggtgtgc tagccgatat agaggaaaat gcctttctag tccctgttcg
     1021 cgctctgcga gatgagggag ccagttacca ctatgtggca ccttgtcgtt atatggaaat
     1081 gcagccagag gctattgctg ctattgagga agttttggaa gacagaggga ttccttatga
     1141 agaagtcatg acctggacga cagacggttt ttaccgagaa acggctgaaa aggtggctta
     1201 tcgtaaggaa gaaggctgtg ctgttgtgga gatggagtgt tctgctcttg cggcagtagc
     1261 tcaattgcgt ggggttctct ggggtgaatt gttgttcaca gcagattctc tagcggactt
     1321 ggaccagtac gacagtcgtg actggggctc ggaagctttt aataaggcgc tagaactgag
     1381 tttagcaagt gttcaccacc tttagttgta caggcaaagg atttgtttta tcataaaatg
     1441 tctagctcat acttttcaaa aatatgttta aacgaggtca ccttcctctt gtcctaggca
     1501 tgttgaggtt gggaaaaatc tttaaaatca gaaaaacgta tcatatcagg tgatgaaaat
     1561 tttgatacta tgcgttttat gttggtaaga tttagagtga gatgaaatga tactcttcga
     1621 aaatctcttc aaaccaggtc agcttcacct tgccgtatag atgttactga cttcgtcagt
     1681 tctatccaca acctcaaaac agtgttttga gcaacctgtg actagctttc taagcgatgc
     1741 cttggttctc attgcctata atcaaaaaga gaaattttct cctgaaaagc atatagagta
     1801 gctggcgtta aaagctcctg tcttgctttt ttgacctata gtcacatcta tcaagtattg
     1861 ttcttgccta agctatcaat aaaaaggtgg cattttttag gcttggtgtt agtgaatttt
     1921 gccttatcct atctaagtca tttcgagctt tttatggtac aatggaaaca tgttattcaa
     1981 attatctaag gaaaaaatag agctaggctt atctcgttta tcgccagccc gtcgtatttt
     2041 tttgagtttt gccttggtca ttttactagg ctctcttctt ttgagcttgc cctttgtcca
     2101 agttgaaagc tcacgagcga cttattttga tcatcttttc actgctgtct ctgcagtctg
     2161 tgtgacaggt ctctcaaccc ttccagtagc tcacacctat aatatctggg gccaaataat
     2221 ctgtttgctc ttgattcaga tcggtggtct agggctcatg acttttattg gggttttcta
     2281 tatccagagc aagcaaaagc ttagtcttcg tagccgtgca actattcagg atagttttag
     2341 ttatggagaa actcgatctt tgagaaagtt tgtctattct atttttctca cgaccttttt
     2401 ggttgagagc ttgggagcta ttttgcttag ttttcgcctt attcctcaac ttggctgggg
     2461 acgtggtctt tttagttcca tttttctagc gatctcagcc ttctgtaatg ccggttttga
     2521 taatttaggg agcaccagtt tatttgcttt tcagaccgat ttactggtca atctggtgat
     2581 tgcaggcttg attattacag gcggccttgg ttttatggtc tggtttgatt tggctggtca
     2641 tgtaggaaga aagaaaaaag gacgtctgca ctttcatacg aagcttgtac tattattgac
     2701 tataggtttg ttgttatttg gaacagcaac tactctcttt cttgagtgga acaatgctgg
     2761 aacgattggc aatctccctg ttgccgataa ggttttagtt agcttttttc aaacagtgac
     2821 gatgcgaaca gctggctttt ctacgataga ttatactcag gctcatcctg tgactctttt
     2881 gatttatatc ttacagatgt ttctaggtgg ggcacctgga ggaacagctg ggggactcaa
     2941 gattacgaca ttttttgtcc tcttggtctt tgcacgaagt gagcttctag gcttgcctca
     3001 tgccaatgtt gcgagacgaa cgatcgcgcc gcgaacggtt caaaaatcct ttagtgtctt
     3061 tattatcttt ttgatgagct tcttgatagg attgattctg ctagggataa cagccaaagg
     3121 caatcctccc tttatccacc tcgtatttga aaccatttca gctcttagta cagttggtgt
     3181 aacggcaaat ctgactcctg accttgggaa attggctctc agtgttatca tgccacttat
     3241 gtttatggga cgaattggtc ccttgacctt gtttgttagc ttggcagatt accatccaga
     3301 aaagaaagat atgattcact atatgaaagc agatattagt attggttaag aaaggaaaga
     3361 gcatgtcaga tcgtacgatt ggaattttgg gcttgggaat ttttgggagc agtgtcctag
     3421 ctgccctagc caagcaggat atgaatatta tcgctattga tgaccacgca gagcgcatca
     3481 atcagtttga gccagttttg gcgcgtggag tgattggtga catcacagat gaagaattat
     3541 tgagatcagc agggattgat acctgcgata ccgttgtagt cgcgacaggt gaaaatctgg
     3601 agtcgagtgt gcttgcggtt atgcactgta agagtttggg ggtaccgact gttattgcta
     3661 aggtcaaaag tcagaccgct aagaaagtgc tagaaaagat tggagctgac tcggttatct
     3721 cgccagagta tgaaatgggg cagtctctag cacagaccat tcttttccat aatagtgttg
     3781 atgtctttca gttggataaa aatgtgtcta tcgtggagat gaaaattcct cagtcttggg
     3841 caggtcaaag tctgagtaaa ttagacctcc gtggcaaata caatctgaat attttgggtt
     3901 tccgagagca ggaaaattcc ccattggatg ttgaatttgg accagatgac ctcttgaaag
     3961 cagataccta tattttggca gtcatcaaca accagtattt ggatacccta gtagcattga
     4021 attcgtaaag agggatgacc cctctttttt gatgcctaag atggcaaata gagacagaag
     4081 ccccttgtct tctagtaaaa gttcttcaaa ggctggactt tatggtaaaa tagaaagaag
     4141 tgacaagaga gagtaatact caatgaaaat caaagatcaa actaggaaac tagctacggg
     4201 ctgctcaaaa cactgttttg aggttgcaga tagaactgac gaagtcagta acatctatac
     4261 ggcaaggcga cgttgacgcg gtttgaagag attttcgaag agtataagaa aaaatcagtc
     4321 ccctaaagga gtagattatg aagttattgt ctatcgcaat ttctagctat aatgcagcag
     4381 cctatcttca ttactgtgtg gagtcgctag tgattggtgg tgagcaagtt gggattttga
     4441 ttatcaatga cgggtctcag gatcagactc aggaaatcgc tgagtgttta gctagcaagt
     4501 atcctaatat cgttagagcc atctataagg aaaataaatg ccatggcggt gcggtcaatc
     4561 gtggcttggc agaggcttct gggcgctatt ttaaagtagt tgacagtgat gactgggtgg
     4621 atcctcgtgc ctacttgaaa attcttgaaa ccttgcagga acttgagagc aaaggtcaag
     4681 aggtggatgt ctttgtgacc aattttgtct atgaaaagga agggcagtct cgtaagaaga
     4741 gtatgagtta cgattcagtc ttgcctgttc ggcagatttt tggctgggac caggtcggaa
     4801 atttctccaa aggccagtat accatgatgc actcgctgat ttatcggaca gatttgttgc
     4861 gtgctagcca gttctaactg cctgaacata ctttttatgt cgataatctc tttgtcttta
     4921 cgccccttca gcaggtcaag accatgtact atctgcctgt cgatttctat cgttatttga
     4981 ttgggcgtga ggaccagtct gtcaatgagc aagtgatgat taagtgcatt gaccagcaac
     5041 tcaaggtcaa tcgactcttg atagaccaac ttgatttgtc ccaagtgagt catcccaaaa
     5101 tgcgagaata tctgctgaat catattgaac tcacgacggt gatttccagt accctgctca
     5161 accgatctgg aacagcggag catctggcaa aaaaacgcca attgtggacc tatattcagc
     5221 agaaaaatcc agaagtcttt caggctattc gtaagaccat gttgagccgt ttgaccaaac
     5281 attctgtctt gccagatcgc aaactgtcca atgtcgtcta tcaaatcacc aaatctgttt
     5341 atggatttaa ttaatataag tgttttataa gagggattta agaaaaattt taactttttc
     5401 ttagtccttt ttaatttcag gagattatac tagagtcatc aaataaagaa agactctaag
     5461 gagaatccta tgaaattcaa tccaaatcaa agatatactc gttggtctat tcgccgtctc
     5521 agtgtcggtg ttgcctcagt tgttgtggct agtggcttct ttgtcctagt tggtcagcca
     5581 agttctgtac gtgccgatgg gctcaatcca accccaggtc aagtcttacc tgaagagaca
     5641 tcgggaacga aagagggtga cttatcagaa aaaccaggag acaccgttct cactcaagcg
     5701 aaacctgagg gcgttactgg aaatacgaat tcacttccga cacctacaga aagaactgaa
     5761 gtgagcgagg aaacaagccc ttctagtctg gatacacttt ttgaaaaaga tgaagaagct
     5821 caaaaaaatc cagagctaac agatgtctta aaagaaactg tagatacagc tgatgtggat
     5881 gggacacaag caagtccagc agaaactact cctgaacaag taaaaggtgg agtgaaagaa
     5941 aatacaaaag acagcatcga tgttcctgct gcttatcttg aaaaagctga agggaaaggt
     6001 cctttcactg ccggtgtaaa ccaagtaatt ccttatgaac tattcgctgg tgatggtatg
     6061 ttaactcgtc tattactaaa agcttcggat aatgctcctt ggtctgacaa tggtactgct
     6121 aaaaatcctg ctttacctcc tcttgaagga ttaacaaaag ggaaatactt ctatgaagta
     6181 gacttaaatg gcaatactgt tggtaaacaa ggtcaagctt taattgatca acttcgcgct
     6241 aatggtactc aaacttataa agctactgtt aaagtttacg gaaataaaga cggtaaagct
     6301 gacttgacta atctagttgc tactaaaaat gtagacatca acattaatgg attagttgct
     6361 aaagaaacag ttcaaaaagc cgttgcagac aacgttaaag acagtatcga tgttccagca
     6421 gcctacctag aaaa
//
LOCUS       DBERPV010000060         6256 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.60, whole genome shotgun sequence.
ACCESSION   DBERPV010000060 DBERPV010000000
VERSION     DBERPV010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6256
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.60"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            170..370
                     /locus_tag="ACL8C7_001956"
     CDS             170..370
                     /locus_tag="ACL8C7_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1396090.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATQAVLLDAQKAPEDSALTE"
     gene            395..811
                     /locus_tag="ACL8C7_001957"
     CDS             395..811
                     /locus_tag="ACL8C7_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transmembrane domain-containing protein"
                     /protein_id="HGS1396091.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1042..1749
                     /gene="ccdA2"
                     /locus_tag="ACL8C7_001958"
     CDS             1042..1749
                     /gene="ccdA2"
                     /locus_tag="ACL8C7_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HGS1396092.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1760..2317
                     /gene="sdbB"
                     /locus_tag="ACL8C7_001959"
     CDS             1760..2317
                     /gene="sdbB"
                     /locus_tag="ACL8C7_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HGS1396093.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2691..4082
                     /locus_tag="ACL8C7_001960"
     CDS             2691..4082
                     /locus_tag="ACL8C7_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HGS1396094.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIALPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKVPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4225..5142
                     /gene="adcAII"
                     /locus_tag="ACL8C7_001961"
     CDS             4225..5142
                     /gene="adcAII"
                     /locus_tag="ACL8C7_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HGS1396095.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLDRVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQSKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5150..>6256
                     /gene="phtD"
                     /locus_tag="ACL8C7_001962"
     CDS             5150..>6256
                     /gene="phtD"
                     /locus_tag="ACL8C7_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HGS1396096.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKSDL
                     SASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLIFDPAQITSRTANGVAVPHGDHYHFIPYSQLSPLEEKLA
                     RIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSPQP"
BASE COUNT         1901 a         1154 c         1320 g         1881 t
ORIGIN      
        1 gtaaaatgaa ataagaacag gacaaatcga tcaggacagt aaaatcgaat tctaacaatg
       61 ttttagaagc ctatatgtac tattctagtt tcaatatacc ataactgctc ctagtcaacc
      121 tgcaagtcct gtcccagctc caagctcagc tccgactcaa gatcctagag tggtagcaag
      181 cgcttcggct agctcaacga gcacacaagc tcaagagcaa gttgacaagt ctgaacttcg
      241 tgccttgagt caagagttag accaacgctt gaaagctttg gcaacagtat ctgatccaaa
      301 aatcgatgca acccaggctg tcctcctaga tgctcaaaaa gctccggaag atagtgcctt
      361 gacagagtaa ggtctgcata ctgcagtaga gtctgtgaag gctgccttgg actctctcaa
      421 agatgtgaaa gcaaatgcta gcgacagcaa gcctgcacag gacaagaagg atgcaaaaca
      481 aggaacggaa gatagtaagg attcagataa gatgactgaa acaaactcag ttccggcagg
      541 agtgattgtg gtcagtctac ttgccctcct aggcgtgatt gccttctggc tgattcgccg
      601 taagaaagag tcagaaatcc agcaattaag cacggaattg atcaaggttc taggacagct
      661 agatgcagaa aaagcggata aaaaagtcct tgccaaagcc caaaaccttc tccaagaaac
      721 ccttgatttc gtgaaagaag aaaatggctc agcagagaca gaaactaaac tagtagagga
      781 gcttaaagca atccttgaca aactcaagta aaacatgatt tatgaaatgt cagacctaaa
      841 agacattttc gttcacaaaa gcagtgacga gtaatccttg tcgttgcttt ttggctattt
      901 tgggggataa gatccgcctt gactagcaaa agaaaagatt ggtccaatag tgcccgatac
      961 gattttgcgt agcagaaagc ttacaaataa aattgaatat agtaaaatag gattagaatt
     1021 attaagaaag ttggttcttt attggaaacg atagtatttt taatctctgt ttttctagca
     1081 ggtgttttat cctttttttc tccttgtatt tttcctcttc tgccagtcta tgctgggatt
     1141 ttattggatg atcaagaaag tgcaaaaagc ttttctttgt ttgggagaaa ggttctctgg
     1201 tcaggcttga ttcgaacact ttgctttatc gctggtatct ctctcatttt ctttattcta
     1261 ggctttggtg ctggttactt tggtcatatt ctctatgcaa attggtttcg atatgtcatg
     1321 ggagctatta ttatcatttt gggtcttcac cagatggaaa tttttcattt gaagaaatta
     1381 gaagttcaaa aaagttttac ctttaaaaaa tcagattcta atcgttattg gtcagctttt
     1441 ttacttggta ttacctttag ctttggttgg acaccttgta ttggtccagt tttaagttct
     1501 gttttagcac ttgcggcttc tggaggcaat ggcgcttggc aaggagcgat ttatactctc
     1561 atttacactc tggggatggc ccttcctttc ttggtattgg cactagcttc aggtctagtc
     1621 atgccatatt ttagtaaaat caagcgtcat atgatgctac taaagaaaat tggtggtttc
     1681 ctcattgttt taatgggaat tttgttacta ttaggacaag taaatgttct agctggaatt
     1741 tttgaataaa ggaggacaaa tgaaaaaagt aatgtttgct ggcttaagtc tcttgtcatt
     1801 agttgtattg atggcctgtg gtgaggaaga aactaaaaag actcaagcag cacaacagcc
     1861 aaaacaacaa acgactgtac aacaaattgc tgttggaaaa gatgctccag acttcacatt
     1921 gcaatccatg gatggcaaag aagttaagtt atctgatttt aagggtaaaa aggtttactt
     1981 gaagttttgg gcttcatggt gtggtccatg caagaaaagt atgccagagt tgatggaact
     2041 agcggcgaaa ccagatcgtg atttcgaaat tcttactgtc attgcaccag gaattcaagg
     2101 tgaaaaaact gttgagcaat tcccacaatg gttccaggaa caaggatata aggatatccc
     2161 agttctttat gataccaaag caaccacctt ccaagcttat caaattcgaa gcattcctac
     2221 agaatattta attgatagcc aaggaaagat tggaaagatt caatttggtg ctatcagtaa
     2281 tgcggatgca gaagcagcat ttaaagaaat gaactagaat cgataaaatc tgattacaag
     2341 atgtagtcag attttggtaa cttctaaaac taacttccag tttcccacaa cttagctttt
     2401 agtatgagaa aaacgcgtga catcagtgga aatccgtctt agactaactt ccactggttt
     2461 tctttttctt gatatataag ggttcaaaag cgaaaagact cagaaaaagt gcacgacaaa
     2521 tagccctaaa acagagtcgt cttagagtaa cttccagttt tgggagagag atggaagtta
     2581 ctttgagaag ttacggtagt cagatttttt tagaaaaaca ttttataaat attcacatat
     2641 ctcctatatt tatggtaaaa tagaattatc agtttatttt ggagtcaaag atgaatatat
     2701 ttagaacaaa gaatgttagt ttagataaaa cagagatgca taggcatttg aagttatggg
     2761 atttgatttt gctgggtatc ggagccatgg tagggacagg cgtctttaca atcacaggta
     2821 ctgcagctgc aacacttgct ggcccagccc tagtgatttc aatcgttatt tctgccttgt
     2881 gtgtgggatt atcagccctc ttttttgcag aatttgcctc gcgagtaccc gctacaggag
     2941 gtgcctatag ttacctctat gctatcttag gagaattccc tgcctggttg gctggttggt
     3001 taaccatgat ggagttcatg acagccatat caggcgtagc ttcgggttgg gcagcttatt
     3061 ttaaaggctt gctctctcaa tatgggatag cccttcctca ggctttaaat ggtaccttta
     3121 atcctcaagc agggacattt gttgatttat tgcctattct tgtcttggtc ttggtgactt
     3181 cgcttgtttt actaaatgcc aaggcagcct tacgctttaa ttcgattcta gttattttga
     3241 aattttccgc tttagctctc tttgttttag taggaatttg gaatattaag tttgataatt
     3301 ggagcaattt tgctccttac ggctttggac aaatctatgg agctagtact ggtattatgg
     3361 ctggtgcgtc cttgatgttc ttcggttttt tgggatttga atccatctct atggctgtag
     3421 atgaagtcaa gactcctcaa aaaaatattc ctagagggat tgtcttatcg ctttctatcg
     3481 taaccattct ctatgccttg gtgacccttg ttttgactgg tgtggttcac tatagtcatt
     3541 taaatgtcga tgatgccgtt gcctttgccc ttcgtagtgt tgggattagt tgggcagcca
     3601 actatgtgtc attagtggct atcttgacct tgattacagt ttgtatttcg atgacctatg
     3661 ccctatcgcg tatgatttac agtttagcac gtgacggctt agtgcctgct gcctttaagg
     3721 aattgacgaa gactagcaag gtaccaaaga atgctactat cttgacaggt ctagcttcag
     3781 cagtagcagc aggaatgttc ccactagcca gtattgcagc ctttttaaat atttgtacct
     3841 tagcctactt gatcatgctg gcttatggtc tgattcgctt acggaaagaa aaaggaatgc
     3901 ccaaagctgg ggaatttaaa acaccattgg tacctctgtt accaatttta tcgatcatca
     3961 tttgtttatc cttcatgtta cagtataata tgaacacctg gattgctttc ctagttgcgt
     4021 tgttagtagg aagtattatt tacttcactt atggctataa gcattctacc atagaagaat
     4081 aaagtgaaag tctattgagt tgttgacact cagcagattt ttatatgtga aagaaatttc
     4141 aaattttttc taaaaatatc ttgacagatt aaattttcag gagtagaata tttactagtt
     4201 aattaaatgg ttaaggagtt gttcatgaag aaacaaaatt tatttttagt cctgttaagt
     4261 gtctttcttt tgtgcttggg ggcttgtggt caaaaggaaa gtcagacagg aaaggggatg
     4321 aaaattgtga ccagttttta tcctatctac gctatggtta aggaagtatc tggtgacttg
     4381 aatgatgttc ggatgattca gtcaagtagt gggattcact cctttgaacc ttcggcaaat
     4441 gacatcgcgg ccatctatga tgcagatgtc tttgtttacc attctcatac gctagaatct
     4501 tgggcaggaa gtttagatcc caatctaaaa aaatctaaag tgaaggtttt agaggcttca
     4561 gagggaatga ctttagaccg cgtcccagga ctagaggatg tggaagcagg ggatggagtt
     4621 gatgaaaaaa cgctctatga ccctcacact tggctagatc ctgaaaaagc tggcgaagaa
     4681 gctcagatta tcgctgataa actttcagag gtagatagtg agcataaaga aacttaccag
     4741 aaaaatgcgc aagcctttat caaaaaagct caggaattga ctaagaaatt ccagtctaaa
     4801 tttgaaaaag cgactcagaa aacatttgta acacaacata cagccttttc ttatttagct
     4861 aagagatttg ggcttaatca acttggtatt gcaggtatct ctcctgaaca agaaccaagt
     4921 ccacgacaac taacagaaat tcaggaattt gttaagacct ataaggtgaa aacgattttt
     4981 acagaaagta acgcttcttc aaaagtagct gaaactcttg tcaaatcaac aggtgtgggt
     5041 cttaaaactc tgaatccttt agagtcagac ccacaaaatg acaagaccta tttagaaaat
     5101 cttgaagaaa atatgagtat tctagcagaa gaattaaagt gaggaaagaa tgaaaatcaa
     5161 taaaaaatat ctagcaggtt cagtggcagt ccttgcccta agtgtttgtt cctatgaact
     5221 tggtcgtcac caagctggtc aggttaagaa agagtctaat cgagtttctt atatagatgg
     5281 tgatcaggct ggtcaaaagg cagaaaattt gacaccagat gaagtcagta agagagaggg
     5341 gatcaacgcc gaacaaattg ttatcaagat tacggatcaa ggttatgtga cctctcatgg
     5401 agaccattat cattactata atggcaaggt tccttatgat gccatcatca gtgaagaact
     5461 tctcatgaaa gatccgaatt atcagttgaa ggattcagac attgtcaatg aaatcaaggg
     5521 tggctatgtg attaaggtag acggaaaata ctatgtttac cttaaagatg cggcccatgc
     5581 ggacaatatt cggacaaaag aagagattaa acgtcagaag caggaacgca gtcataatca
     5641 caactcaaga gcagataatg ctgttgctgc agccagagcc caaggacgtt atacaacgga
     5701 tgatgggtat atcttcaatg cttctgatat cattgaagat actggtgatg cttatatcgt
     5761 tcctcacggc gaccattacc attacattcc taagagtgat ttgtctgcca gtgaattagc
     5821 tgctgcccaa gcctattgga atgggaagca gggatctcgt ccttcttcaa gttctagtca
     5881 taatgcaaat ccagctcaac caagattgtc agagaaccac aatctgactg tcactccaac
     5941 ttatcatcaa aatcaagggg aaaacatttc aagcctttta cgtgaattgt atgctaaacc
     6001 cttatcagaa cgccatgtag aatctgatgg ccttattttc gacccagcgc aaatcacaag
     6061 tcgaaccgcc aatggtgttg ctgtaccgca cggagaccat tatcacttta ttccttattc
     6121 acaactgtca cctttggaag aaaaattggc tcgtattatt ccccttcgtt atcgttcaaa
     6181 ccattgggta ccagattcaa gaccagaaca accaagtcca caatcgactc cggaacctag
     6241 tccaagtccg caacct
//
LOCUS       DBERPV010000061         6186 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.61, whole genome shotgun sequence.
ACCESSION   DBERPV010000061 DBERPV010000000
VERSION     DBERPV010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6186)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6186)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6186
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.61"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(137..316)
                     /locus_tag="ACL8C7_001963"
     CDS             complement(137..316)
                     /locus_tag="ACL8C7_001963"
                     /inference="COORDINATES: protein motif:HMM:NF012798.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGS1396097.1"
                     /translation="MQKANTKLEKPINQPLSSHIFRHTLLSTLAEKNAIMVRVEHKNA
                     KTVNNIYTHVSKRME"
     gene            complement(648..755)
                     /locus_tag="ACL8C7_001964"
                     /pseudo
     CDS             complement(648..755)
                     /locus_tag="ACL8C7_001964"
                     /inference="COORDINATES: protein motif:HMM:NF012920.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="S26 family signal peptidase"
     gene            1555..2427
                     /locus_tag="ACL8C7_001965"
     CDS             1555..2427
                     /locus_tag="ACL8C7_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HGS1396098.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(2573..2917)
                     /locus_tag="ACL8C7_001966"
                     /pseudo
     CDS             complement(2573..2917)
                     /locus_tag="ACL8C7_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            3060..3371
                     /locus_tag="ACL8C7_001967"
     CDS             3060..3371
                     /locus_tag="ACL8C7_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1396099.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEHPELYAVAQTSGEIPEKKREELRQIITTIFEQKMNKHSI
                     K"
     gene            3375..4073
                     /locus_tag="ACL8C7_001968"
     CDS             3375..4073
                     /locus_tag="ACL8C7_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGS1396100.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYLASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVLDLALLISKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALFDTIFLENFGHELYTQAPK
                     EIAILMNEWLAYFL"
     gene            complement(4202..5017)
                     /locus_tag="ACL8C7_001969"
     CDS             complement(4202..5017)
                     /locus_tag="ACL8C7_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HGS1396101.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(5014..5919)
                     /locus_tag="ACL8C7_001970"
     CDS             complement(5014..5919)
                     /locus_tag="ACL8C7_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HGS1396102.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            complement(5920..6051)
                     /locus_tag="ACL8C7_001971"
     CDS             complement(5920..6051)
                     /locus_tag="ACL8C7_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HGS1396103.1"
                     /translation="MAVKFTKRDDLDKMFEEFAKLPDLKQVTFPDDKEKKVKAEKKN"
BASE COUNT         1960 a         1072 c         1236 g         1918 t
ORIGIN      
        1 aaataagata tgcacaaatt gattagaaag tcaaatgaat ttctacaaat gttttagcaa
       61 tcgtaatgta cttgtctaga ttcgatctga tatattttcg atttaatgat atggtattta
      121 aaacctccaa agtagcttac tccattcttt tacttacgtg agtgtagatg ttatttactg
      181 ttttagcgtt tttgtgttcc actctaacca ttatagcatt cttctcagct agtgtactaa
      241 ggagtgtgtg cctgaaaata tgggaactaa ggggctggtt tatcggtttc tctagtttag
      301 tatttgcctt ttgcaaagtg atgttaaatg cctttctcta aatttacata tcactattgt
      361 ttaacaaaat ctaatctatt ttaggtcact tattcttttt ttgaaatgta gaatgaactt
      421 tttcaaagtt tttcgaatct tttaaaatct gtttgtttta tatcgccatt ctcccccttt
      481 tttaattctc cctatatagc ctgacaactt tcccgatggt acgaatatgg ttgctttcgt
      541 ctaggtggat gtcggggtat ttgggattga gtttttttaa ggtagccttg gcggagtttc
      601 ttgacatagt tagcgccgtc tacttggaag atgccgatgg tattatagtc aatctgtggg
      661 gtattcttga taaataggta gtcgctgttt cttatctttg gctccatgga cttgctgacg
      721 acataagcga ttgggtcgta gtcgtctggg ataatggaaa ctccatatct aaatcgttgt
      781 cctgcatcga gcggctacct gcagagataa actacctaac acgagagtaa gtagtctgtc
      841 tgtagtcgtc cagtctgatg atttttacga tacttcgttt ttctgatcat acagttgcct
      901 ctcggcatag gtcagaactt taccttgtct gggtggtgcc cgttggtcgt agatagattg
      961 gatatcgcta ggagaatcct tttgaactgg agaaaagagg gcatcaatca agctactgaa
     1021 tactttaact aagtcaaata tagtattttt cttagtagac ctaacccttt tttcataatt
     1081 tctaatggtg tttttactta tacctatctt agtacccaat tcttattgag tccaaccatt
     1141 actagtctat attgttttat agttgattga gtttggaata gtacgctgta gctgctaaaa
     1201 catttctagg aattaatttg cctttcctaa tagagttgtt catatcttat ttcaatctat
     1261 tatgtttttc acctctaaca atcgcaatct cttctttatc tacgaatgaa atcgctttct
     1321 atttttgtaa gtaaagcatc acacgaaatc cacgaaaatg aaaacctttg ttgtgttttc
     1381 gtaaaaaatt tgttgacaga gcacgaaacg cctactataa ttaaatcaag cttaaggaaa
     1441 taacaaaaaa acaaatcgga gggaaagacg atgaacacat taaatgagaa agtaatcaat
     1501 atctgtaaag cagtagttaa agaaacttta atccaagaca tttaggagaa agaaatgaag
     1561 aaatcaagaa aattagccac attaggaatc tgttcagctt tgtttttagg cttggctgct
     1621 tgtcaacaac aacatgctac ttctgagggg acgaatcaaa ggcaaagcag ttcagcgaaa
     1681 gttccatgga aagcttcata caccaaccta aacaaccagg taagtacaga agaggtcaaa
     1741 tctctcttat cagctcactt ggatccaaat agtgttgatg cattttttaa tctcgttaat
     1801 gactataata ccattgtcgg ctcaactggc ttatcaggag atttcacttc ctttactcac
     1861 accgaatacg atgttgagaa aatcagtcat ctctggaatc aaaagaaggg cgatttcgtt
     1921 gggaccaact gccgtatcaa tagttattgt cttttgaaaa attcagtcac cattccaaag
     1981 cttgaaaaga atgaccaatt gcttttccta gataacgatg cgattgataa aggaaaggtc
     2041 tttgattcac aagataagga agagtttgat attctatttt cgagagttcc aactgaggca
     2101 actacagatg tcaaggttca cgctgaaaag atggaaacat tcttctcaca atttcaattc
     2161 aatgaaaaag ctcgaatgct gtctgtagtc ttgcacgaca atctggatgg cgagtatctg
     2221 tttgtaggcc acgttggggt cttagtacct gctgatgacg gtttcttatt tgtagagaaa
     2281 ttgactttcg aagagcccta ccaagcgatt aaatttgcta gtaaggaaga ttgctacaag
     2341 tatttaggca ccaagtatgc ggattataca ggcgagggac tggctaagcc ttttatcatg
     2401 gataatgata agtgggttaa actttaatag tgttatgata tgacagtaat cttaggattt
     2461 ttatttctat ttttgatgac ttggtgggtt atttcaatcg ttaatagcca gaaaccacgc
     2521 aaaaatgaaa catttattgg ctatatccaa agatacgata ttgatgggaa tggctatcaa
     2581 tcattaccgt gtcctcagaa ctgagaggag ttcttgaaat cgtaaaacta ctttgaacaa
     2641 gagttacttc aacccattgg ctccgacgga ttaagttgct ttcgtgaaca ccaaaatcag
     2701 ccgcaatttc ttcataagtg cggtattctc gcacatattg aagagtggcc ataagaaggt
     2761 cttctaggct taatttaggt tttcgtcccc cttttgtgtg tttaagttga taagcagttt
     2821 ttaatacagc taacatctct tcaaaagtgg tgcgctgaac accaacaaga catttaaatc
     2881 gtgcatcagt tagttgctta cttgcttcat aattcataga actactatac catattttgt
     2941 ttcgcaggaa gtctaatgct aaaatcttat cagtgagaag atttcttaaa gtttattctt
     3001 tgtagtttca tctgtattag tacataattt aacttagaga aaataggagg actaatcgaa
     3061 tggaattaaa agattttaca gaaaaagaac aggaaatgat taagaaaagg cttacaatgt
     3121 ctaatattag tgacaaagaa actactgaga agattctggc gctagtacca caagacttga
     3181 ttaagcgaat cccgtttttt gtcagaaaac atgctacaac acgtacgatt aaacgcattt
     3241 caattgaaca ccctgaactc tacgctgtag ctcaaacaag tggtgagatt ccagaaaaaa
     3301 aacgcgaaga attgcgtcag attatcacaa ctatctttga acaaaagatg aataagcata
     3361 gtattaagta gagaatgaaa aaatatttta ttggcggttt gggaagcaat gcctatcata
     3421 gcaaggattt tcttcaagaa ctagattcgc aggtctattt tctaaatcca tatgaaaagc
     3481 atcttcgaga tgaaacagaa ttgaaatcat ggtttaaaaa tgagattgta gaggaagaat
     3541 ctatctgtct gataggccat tctcttggag gagatttagc tcgttatctc gcatcggaat
     3601 ttgaagaagt aaaaaaactg attcttttgg atggtggcta tctagattta gataagattt
     3661 tacctttgga tacagagtta gaggaaacta aaaattatat caaatctcaa attgttttgg
     3721 acttagctct tcttatttct aaagaaaaat ctgaagcaaa gcattggtca gaaaatatgg
     3781 agaaagctgt aagacagtct tatcactgga atgttgagta taatagatat gagttggcta
     3841 taaattatga aaatatagaa gcgatactcc gcctacggag aaaaatacaa gcttttaaga
     3901 gagaagtggg agataccttg tttattagtc ctcgctatcc taatgaagct acatggagag
     3961 aggaagccct atttgatact atttttttag aaaactttgg ccatgagctt tatactcaag
     4021 cacctaaaga aatcgctatt ctaatgaatg agtggctcgc ttattttcta tgagctactt
     4081 gtattgctgg aaatggtata agatgaaaat ctacaagtca ctaattttca tataacaaaa
     4141 aacgaacagg ctctttttct gttattcaga agagaacttg ttcgttttta tcttgatttt
     4201 cttaaaaagc tctatataca tagggatttt ctggtttatc gactttggta aagctgtcga
     4261 tttccaaggt tggaaggttt tgtttgagtt ctttatggta gtgattgacc agttttcctt
     4321 tggctgttat ccaagtgttg ttttcatact gccgggtatt gcccttggtc agcaatccat
     4381 agacaccaga atctgcgata cagtggataa tgccgaagcg gaacagaaat tggctattgg
     4441 catgactggg gtcgttatag acaaagcctg taaactggat tgtcttgccc tcaaactcat
     4501 ctggatagtc gtagatagcc tccatgactt ccatatagtt ttcattagtg atctgaatac
     4561 tatcttggga taagtattta tccgccgccg ttcgcatttc cttttcatag gctgattttg
     4621 aaaaataaga actggtatct ggtttcaaat attggcttgt cgtcccttcg cttgtctgaa
     4681 tggctagatc cgttccttct gataggggga aatgataacc tttagcagaa acggtctgag
     4741 aatccaagct aacagttggg aaagttaagc cgatgacaag tggaatagcc agaagagaaa
     4801 tactcgtcat cttggctaat cggctgttca gatgactgtg ggttttgact tgcttcatcc
     4861 agatatacaa ttgaacaata gccaagataa aggaaagcac catggaaata taggccagat
     4921 aggaatagtg catgttgatg tactggttta gtttgcccga cagatggagg taaatagtca
     4981 gttcaaaata gccagctaaa actaaaaatc gaatcatagg atgactccaa tcaagagaga
     5041 ataggctaaa acgaccagag tcacaatcgt aatgaagtga ctaataaatc gtgctttcaa
     5101 gtaatttttc atcatgagaa tatttttgat atccagcatt gggccaatga cgagaaaggc
     5161 cagaactgga gccaaaccga aactcgagag tagagaagca cctataaagg catccgcctc
     5221 actacagagc gaaagaagaa aggccaaaag catcaagagc aggatggcaa aaagaggagt
     5281 cgcactgata gaggtcagaa tccgagtcgg aacgtagacc tgtattatag aagcaaagag
     5341 gcagccaaat accaaataac gccccgtatc aaaaaattca tcaatggcct gcacaaagac
     5401 ttgaaaaact ttttttgcag aactcaagta agaaaaatca tgctcatgac aagccagacg
     5461 attttctttc tgaatcggtt cttgccagaa aaatcctaga aaaattccta gtattacagc
     5521 cacaagaatg gaacccagag ctcgtaatag ggcgacatgg aaggagttgc caaaggcaga
     5581 ataggtcgca aaaagaacaa tgggattgat aacaggtgct gtcacaagaa aaggaacggc
     5641 cgtgtaactt ggaacctttt tttccagaaa acgattgatg atggggacga ttccacattc
     5701 acaagaaggg aaaagtatac cgacaaaggt cccaaaaaag attctccccc aacgatttcg
     5761 agggagaaaa tgataaacct tgtcaggtgt gatataaact tcaatcagcc ctgagacaat
     5821 gcttcctatc agaacgaagg gaagggcttc aatgataatg gagagaaaaa tggctccagt
     5881 ttgaagtaca ctagatggga gttgttgaaa agcagtcatc tagtttttct tttctgcttt
     5941 gacttttttc tctttgtcat cagggaaagt aacttgtttc aaatcaggga gtttagcaaa
     6001 ctcttcaaac atcttgtcca agtcgtctcg ttttgtaaat ttgacagcca taggtgtacc
     6061 tcgattctaa attctacctc tattatacta ttattttgcg gaaaagggag ttttttaatt
     6121 tgttttcgat agttgatact cttcgaaaat ctcttcaaac cacgtcagct tcgccttacc
     6181 gtagta
//
LOCUS       DBERPV010000062         5906 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.62, whole genome shotgun sequence.
ACCESSION   DBERPV010000062 DBERPV010000000
VERSION     DBERPV010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5906
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.62"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(184..1194)
                     /gene="ccpA"
                     /locus_tag="ACL8C7_001972"
     CDS             complement(184..1194)
                     /gene="ccpA"
                     /locus_tag="ACL8C7_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HGS1396104.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGIAYSEGL
                     VFESKYTYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(1619..2218)
                     /locus_tag="ACL8C7_001973"
     CDS             complement(1619..2218)
                     /locus_tag="ACL8C7_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS1396105.1"
                     /translation="MKLLVAEDQSMLRDAMCQLLTLQPDVESVFQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRAEKLETKVVVVTTFKRPGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTHPNPLTEQEIAVLKGIARGFSNQEIA
                     DKLYLSNGTVRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(2220..3317)
                     /locus_tag="ACL8C7_001974"
     CDS             complement(2220..3317)
                     /locus_tag="ACL8C7_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGS1396106.1"
                     /translation="MLERLKSIHYMFWISLIFMVFPILPVVTGLLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGILLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVGGLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLFYLLVILAFVDLMTFGLVRIRIVEDLKEAQ
                     AKQNAQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVQVENHLDKASLTQDV
                     ESTAAMILLELVTNIIKHAKAFKVYLKLERTEKELILTVRDDGCGFTSIKGDDLHTVR
                     DRVLPFSGEVKVISWKQPTEVQVLLPYKERN"
     gene            complement(3317..4054)
                     /locus_tag="ACL8C7_001975"
     CDS             complement(3317..4054)
                     /locus_tag="ACL8C7_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1396107.1"
                     /translation="MKRWIALNKIEFLLTKRQSVYYLLSVGMPTAFYLFFSSMYQDTP
                     GGPANFMRDYLISMTAFSMMSTAIFSFPVVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFSVGHFVRGVDMSLASWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQVVGKCLPTYQLMELIKTFLNEGGINL
                     SATVYLLVFSVVLFGLTIYLQGHKENA"
     gene            complement(4056..4940)
                     /locus_tag="ACL8C7_001976"
     CDS             complement(4056..4940)
                     /locus_tag="ACL8C7_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1396108.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(4927..5121)
                     /locus_tag="ACL8C7_001977"
     CDS             complement(4927..5121)
                     /locus_tag="ACL8C7_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1396109.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIRGALGFGFM
                     IFVVFLMGMEWLKGESHDGG"
     gene            complement(5118..5324)
                     /locus_tag="ACL8C7_001978"
     CDS             complement(5118..5324)
                     /locus_tag="ACL8C7_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1396110.1"
                     /translation="MGEEEMRNKMIIAVSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT         1889 a         1316 c          955 g         1746 t
ORIGIN      
        1 agtttcatct acaacctcaa aaacatgttt tgagctgact tcgtcagttc tatctacaac
       61 ctcaaaacag tgtgttgcgc agcctttaac cagccgccta gtccgctcta tggtattcat
      121 taagtcaaca tctcttgttt aagagcacaa aatcaggaaa tcttctcgat tccctgattt
      181 tttctattta cgttttcgtg ttgagctacg ttctgtcaaa ccatgaggta agagaacttc
      241 acgttcttcc aactcttcct tatgcataat cttggtcaac atacgcatac taatggcacc
      301 aaggtcataa agaggttggg caatcgttgt caagtttgga cgggtaaagc gtgagatttg
      361 tgaatcatca ctagtaataa tttcaaaatc ttctggcaca gaaacaccct tatcagccaa
      421 accgttcaag actcctgctg ccaactcatc acctgtcaca actgctgcag ttgcatttga
      481 tgaaatcaaa cgctctgcta aggcgtaacc atcatcatag gtatatttag attcaaatac
      541 caaaccctca ctataagcga ttcctgcttt tttcaaggtt tccttgtagc caactaaacg
      601 aaccttacca ttgatgtcat ccactagcgg accgctaacg aaagcaatac gctcattttc
      661 tttagcaagg taactcactg catcaattgt tgcttgctta tagtcaatat tgacacttgg
      721 caactggtgc tcaacatcga cagttcctgc gagaacaatc ggagtacgtg aacgcgaaaa
      781 ttctgagcga attttatctg tcaagtgata acccatatag ataatgccat ctacctgctt
      841 tgaaaagagg gtattgacaa cagaaacttc tttctcgtta tcttcatcgc tattagctag
      901 gacaatattg tacttgtaca tttctgcaat atcatcaatc cccttagcca aactcgaaaa
      961 ataaccattg gtaatatttg gaatcacgac accgacagtg gttgtctttt tacttgcaag
     1021 accacgcgca actgcatttg gacgataatc caagcgatca attacctcta gcactttttt
     1081 acgggtattc tcttttacat ttttattgcc attgaccaca cggctgaccg tcgccatgga
     1141 aacacctgct tcacgagcga catcataaat ggttactgta tcatctgcat tcattccttt
     1201 tcctgtcctt tctatctcac acattctttt acaagtagag gtactgattg aagctctata
     1261 tctacttaca aaagtgaaga tgtgaaaatt tcgttttcat atttctactt attccattct
     1321 atcactaatt gtaaacactt tcaagtgttt tttgaagatt gattgaaaaa atttcataga
     1381 aaacctaggt ttagctcctt gctaccacct tagactaaac aaaaaggagg aaactaagcc
     1441 ctcctaaagt tatagtaaaa tgaaataaga acaggataaa tcgatcagga cagtcaaatc
     1501 gatttctaac aatgttttag aagtagaggt gtactattct agtttcaatc tactataggt
     1561 attgttccat tcactaccgt caattttagc acatagtctt catgaaaata ttatatcatc
     1621 acaaccaacc agattctttc gcgatattag ctgcctctgt tcgattacca gcatctagtt
     1681 tcgaaagaat attggtgaca tagttacgga cggttccgtt ggatagataa agtttgtctg
     1741 caatttcttg gttagagaat ccccgagcaa ttccctttaa aacagcaatc tcttgttctg
     1801 tcaacggatt aggatgcgtc atcaccactt ccatcaattc aggcgaatac tccttgcgcc
     1861 cttcgaggac ggtgtgcaag gtttgcatga ggtctgcaat gcttctttct ttcaagacat
     1921 aagcatccac tccagccttg accgcacgtt caaaataccc tggacgcttg aaggtcgtca
     1981 ccacaaccac ctttgtttcg agtttttctg ctcgtatcca ctccaagact tcgaggcccg
     2041 tcttaacagg catttctacg tcaaggatgg cgatatctac agactccttt tctaatagtt
     2101 ggattgcttc ttgcccattc ttggcttgaa agacagactc tacatctggt tgaagcgtga
     2161 gcaactggca catggcatct cgcaacatac tttgatcttc tgcaacaagt agtttcatct
     2221 tagtttctct ccttataagg tagtagaacc tgaacttctg tcggttgttt ccaactaatt
     2281 acctttactt ctcccgaaaa tggaagaaca cgatctcgaa ctgtatggag gtcatccccc
     2341 tttatggaag taaagccaca gccatcatct ctcactgtta gaatgagttc tttctctgtc
     2401 cgttctaatt ttaagtagac tttaaacgct ttagcatgtt tgatgatatt ggtcactaat
     2461 tcgagcaaaa tcatagcagc cgtcgactcc acatcctggg tcaagctagc cttgtctaag
     2521 tgattctcaa cttgaacctc aattccagca atttctaaca tctttttcac agtctctagt
     2581 tcggatgtca aagttctaga cttaagattt tccacaatgg ttcgcacttc attcatggaa
     2641 tccttgctga tctggtgaat ttcttttaat tccttttcca cctgtggata agcctccatc
     2701 tgaaataact gcaaggctag atcagtttta acactaagca tagcaaaggt atgccccaga
     2761 ctatcatgca aatcttgacc gatacgattg cgttcatttt cagcaagcaa tagatttatc
     2821 tgggcatttt gcttagcctg tgcttctttc aaatcctcca caattcgaat ccgaaccaag
     2881 ccaaaagtca ttaaatcgac aaaagcaaga attacaagta gatagaatag aaactcaact
     2941 tcgattctct gaaaaatcaa cagttgaccc acaacaagga cttgagcaag aagaaaagtc
     3001 cagacatgta aagactttaa accacctacg ctgaaatgat agcttaagag attggatagg
     3061 aaaaagaaaa accagatata attaacagcc acaaaggcag tattcccaac tacataagtc
     3121 agcaggatgc cccaatatag ccaagataga cgctggctct tagttgttaa aacacccaaa
     3181 tacgccacta caaatagaat atcaatcaat aaatgccagg cagaaagcaa cccagtcact
     3241 acaggtagga tggggaaaac cataaaaatt aaactgatcc aaaacatata atgtatgctt
     3301 ttcagtcttt caagcattaa gcattctcct tatgaccttg aaggtaaatg gtcaaaccaa
     3361 acaaaactac tgaaaaaaca agtaaataaa ctgtggctga tagattgatt ccaccttcat
     3421 ttaagaaggt cttgattaat tccatcaact gatatgttgg aagacactta cccactactt
     3481 gcatccagtc tggaaataaa gagataggca tccaaagtcc acctaaaaca gccaatccta
     3541 gataaagaag attacccacg acagacatca gctgactagt cggtaagaga gtcaaggtca
     3601 agccaagcgc tacaaaagca atacttccca caatcagcaa aatcgcagct ccaacccagc
     3661 ttgctagaga catgtccaca cctcttacaa aatgcccaac tgagaaaacc accaagattg
     3721 aaaccaaata atcaaccagc atacttgtta tctttgatag ataatattct accatattta
     3781 cagggctatg acgtaatgtt ttctgccagt tgttcatctt gtcggtatgt aaaacaactg
     3841 gaaatgagaa gatagctgtc gacatcatag aaaaggcagt catggagata agataatcac
     3901 gcataaaatt cgcgggtcca cctggtgtat cctggtacat gctagaaaag aatagataga
     3961 aggctgtcgg catccctact gataataaat aatagactga ttgccgtttg gtcaatagaa
     4021 attctatctt atttaatgct atccatcgtt tcatcttagt tatctccctt ctgcgtctct
     4081 tcaaagattg tattcaacaa actacgatta ttaacttcga tttcttgcat cctacatcct
     4141 gcttgggcta atagttccca gaaagcatct gcttctcgag tgactacttg taaagaatct
     4201 tgctttaggg tccagttttc aaccaaattt gactgctcta cgacttcctt gtaagctata
     4261 ggaaggataa agtgcttttc tatttcctcg ctacgcatag ctagaggcgt cgtatctcga
     4321 atcaactctc ccttatttaa gagcaaaatg cggtctgcag tgtgttccac ttcctcaata
     4381 taatgggacg aatagagaat ggtgactcct tgcgctttta actcctggac aatttcccaa
     4441 aaacgttgac gagttgaggt atccatggac gcagtaggct catctaaaaa aacaatcttt
     4501 ggtcgcccaa ttaaggtcaa gacgaaagaa aagagacgct tttgaccgcc tgataatttt
     4561 tctgccaact gttctttttg ttgcttgaca aactgcaata gttgatcaat ttcctgattg
     4621 ctcaaaggat ttggatagat acgttgaaag aaagcaatca actctttaac ttttaatttc
     4681 tgaacgatta cattttcttg agggaggtaa gccctagtat agtctaactt agaactcgtc
     4741 actggtaaac cttgaataga tacttgaccg cttgtgacca gtttatctcc aagcaaacaa
     4801 tctaagagtg ttgtctttcc ggcaccattt ggaccaatta aggcaacaca ttcaccatcg
     4861 ttgatttcaa aggagatatt ccgcaaaatt tccttgtctt ttattttctt actcaatttc
     4921 tcaactttaa ccaccgtcat gagactctcc tttcaaccac tccattccca taaggaaaac
     4981 gacgaaaatc ataaatccaa accccaaagc accacgaatg aattggcgaa gcaaggcttg
     5041 atcaaaccaa tcagtaaaca tttccactaa ccataccaag agtgacaggc cgataaagaa
     5101 atagatgatc cctctcttca ttcctcaaac tcctttttca catctctgac taatttcaaa
     5161 ccttctctaa caagccaaga catgattcca aagccagcaa agaccttcca aggaaaatgg
     5221 tagaaatcct catccaatcc cgaaaacatg agataggtca taactcctgc tactactaaa
     5281 cttactgcga taatcatttt atttctcatc tcttcttccc ccatttcata ctacaattat
     5341 agtcttttaa aatcagagga ggcagaagct tctgtcacta gaaaatatga caaatgtcat
     5401 aaaaaattct gttcaaaaca agcaagatac actatacaat aaaacacaat cagaaaaatc
     5461 taaggcaact tcctcaaaag agatatcaaa cccaattcac accataatgt aaactaatac
     5521 ttatttaaaa tcaaaaagag tagaaatttt tatcagacaa acacatatat agtgtattga
     5581 atctataaca gtagggctta aatactaaaa tatttctata aattaattta actttcctga
     5641 tagagctgtt catatcttat ttcaattctc tatattatac gttgaacaaa acccttctat
     5701 tgctttctta aaaatttata agagttataa aatctgttaa atttcaatgt gtatacctaa
     5761 actacggtat ttattgaaaa gactggggac aaaaagtata cgctgccaaa atgaattact
     5821 gaaaatcaaa aaagagagaa ccaaactgat tccctcttaa tgtatataat atctagtttt
     5881 aaaaatacac actcacatat ctctgt
//
LOCUS       DBERPV010000063         4931 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.63, whole genome shotgun sequence.
ACCESSION   DBERPV010000063 DBERPV010000000
VERSION     DBERPV010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4931
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.63"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            64..1609
                     /locus_tag="ACL8C7_001979"
     rRNA            64..1609
                     /locus_tag="ACL8C7_001979"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1661..1733
                     /locus_tag="ACL8C7_001980"
     tRNA            1661..1733
                     /locus_tag="ACL8C7_001980"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1694..1696,aa:Ala,seq:tgc)
     gene            1858..4759
                     /locus_tag="ACL8C7_001981"
     rRNA            1858..4759
                     /locus_tag="ACL8C7_001981"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            4836..>4931
                     /gene="rrf"
                     /locus_tag="ACL8C7_001982"
     rRNA            4836..>4931
                     /gene="rrf"
                     /locus_tag="ACL8C7_001982"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1379 a         1007 c         1454 g         1091 t
ORIGIN      
        1 tagtactgaa caatgaaaaa acaataaatc tgtcagtgac agaaatgagt gagaactcaa
       61 acttttaatg agagtttgat cctggctcag gacgaacgct ggcggcgtgc ctaatacatg
      121 caagtagaac gctgaaggag gagcttgctt ctctggatga gttgcgaacg ggtgagtaac
      181 gcgtaggtaa cctgcctggt agcgggggat aactattgga aacgatagct aataccgcat
      241 aagagtagat gttgcatgac atttacttaa aaggtgcact tgcatcacta ccagatggac
      301 ctgcgttgta ttagctagtt ggtggggtaa cggctcacca aggcgacgat acatagccga
      361 cctgagaggg tgatcggcca cactgggact gagacacggc ccagactcct acgggaggca
      421 gcagtaggga atcttcggca atggacggaa gtctgaccga gcaacgccgc gtgagtgaag
      481 aaggttttcg gatcgtaaag ctctgttgta agagaagaac gagtgtgaga gtggaaagtt
      541 cacactgtga cggtatctta ccagaaaggg acggctaact acgtgccagc agccgcggta
      601 atacgtaggt cccgagcgtt gtccggattt attgggcgta aagcgagcgc aggcggttag
      661 ataagtctga agttaaaggc tgtggcttaa ccatagtagg ctttggaaac tgtttaactt
      721 gagtgcaaga ggggagagtg gaattccatg tgtagcggtg aaatgcgtag atatatggag
      781 gaacaccggt ggcgaaagcg gctctctggc ttgtaactga cgctgaggct cgaaagcgtg
      841 gggagcaaac aggattagat accctggtag tccacgctgt aaacgatgag tgctaggtgt
      901 tagacccttt ccggggttta gtgccgtagc taacgcatta agcactccgc ctggggagta
      961 cgaccgcaag gttgaaactc aaaggaattg acgggggccc gcacaagcgg tggagcatgt
     1021 ggtttaattc gaagcaacgc gaagaacctt accaggtctt gacatccctc tgaccgctct
     1081 agagatagag ttttccttcg ggacagaggt gacaggtggt gcatggttgt cgtcagctcg
     1141 tgtcgtgaga tgttgggtta agtcccgcaa cgagcgcaac ccctattgtt agttgccatc
     1201 atttagttgg gcactctagc gagactgccg gtaataaacc ggaggaaggt ggggatgacg
     1261 tcaaatcatc atgcccctta tgacctgggc tacacacgtg ctacaatggc tggtacaacg
     1321 agtcgcaagc cggtgacggc aagctaatct cttaaagcca gtctcagttc ggattgtagg
     1381 ctgcaactcg cctacatgaa gtcggaatcg ctagtaatcg cggatcagca cgccgcggtg
     1441 aatacgttcc cgggccttgt acacaccgcc cgtcacacca cgagagtttg taacacccga
     1501 agtcggtgag gtaaccgtaa ggagccagcc gcctaaggtg ggatagatga ttggggtgaa
     1561 gtcgtaacaa ggtagccgta tcggaaggtg cggctggatc acctcctttc taaggataag
     1621 gaactgcgca ttggtcttgt ttagtcttga gaggtcttgt ggggccttag ctcagctggg
     1681 agagcgcctg ctttgcacgc aggaggtcag cggttcgatc ccgctaggct ccattggtga
     1741 gagatcacca agtaatgcac attgaaaatt gaatatctat atcaaatagt aacaagaaaa
     1801 taaaccgaaa acgctgtagt attaataaga gtttatgact gaaaggtcag aaaataaggt
     1861 taagttaata agggcgcacg gtggatgcct tggcactagg agccgacgaa ggacgtgaca
     1921 aacgacgata tgccttgggt agctgtaagt aagcgatgat ccagggattt ccgaatgggg
     1981 gaacccaaca ggtaatacct gttacccaca tctgttaagg atgtgaggag gaagacgcag
     2041 tgaactgaaa catctaagta gctgcaggaa gagaaagcaa aagcgattgc cttagtagcg
     2101 gcgagcgaaa cggcagaagg gcaaaccgaa gagtttactc ttcggggttg taggactgca
     2161 atgtggactc aaagattata gaagaatgat ttgggaagat cagccaaaga gagtaatagc
     2221 ctcgtattta aaatagtctt tgtacttagc agtatcctga gtacggcggg acacgtgaaa
     2281 tcccgtcgga atctgggagg accatctccc aaccctaaat actccctagt gaccgatagt
     2341 gaaccagtac cgtgagggaa aggtgaaaag caccccggga ggggagtgaa atagaacctg
     2401 aaaccgtgtg cctacaacaa gttcgagccc gttaatgggt gagagcgtgc cttttgtaga
     2461 atgaaccggc gagttacgtt atgatgcgag gttaagttga agagacggag ccgtagggaa
     2521 accgagtctg aatagggcgc cttagtatca tgacgtagac ccgaaaccat gtgacctacc
     2581 catgagcagg ttgaaggtgc ggtaagacgc actggaggac cgaaccaggg cacgttgaaa
     2641 agtgcttgga tgacttgtgg gtagcggaga aattccaaac gaacttggag atagctggtt
     2701 ctctccgaaa tagctttagg gctagcgtcg acattagaga ttcttggagg tagagcactg
     2761 tttgggtgag gggtccatcc cggattacca atctcagata aactccgaat gccaatgaat
     2821 tatggtcggc agtcagactg cgagtgctaa gatccgtagt cgaaagggaa acagcccaga
     2881 ccaccagcta aggtcccaaa ataattgtta agtggaaaag gatgtggggt tgcacagaca
     2941 actaggatgt tagcttagaa gcagctattc attcaaagag tgcgtaatag ctcactagtc
     3001 gagtgaccct gcgccgaaaa tgtaccgggg ctaaaacaat ttaccgaagc tgtggatacc
     3061 tttataggta tggtaggaga gcgttctatg tgtgatgaag gtataccgtg aggagtgctg
     3121 gaacgcatag aagtgagaat gccggtatga gtagcgaaag acaggtgaga atcctgtcca
     3181 ccgtaagact aaggtttcca ggggaaggct cgtccgccct gggttagtcg ggacctaagg
     3241 agagaccgaa aggtgtatcc gatggacaac aggttgatat tcctgtacta gagtatgtag
     3301 tgatggaggg acgcagtagg ctaactaaag cagacgattg gaagagtctg tctaagcagt
     3361 gaggtgtgaa ttgagtcaaa tgcttaattc tataacattg agctgtgatg gggagcgaag
     3421 tttagtagcg aagttagtga cgtcacactg ccaagaaaag cttctagcgt ttaaacatac
     3481 tctacccgta ccgcaaaccg acacaggtag tcgaggcgag tagcctcagg tgagcgagag
     3541 aactctcgtt aaggaactcg gcaaaatgac cccgtaactt cgggagaagg ggtgctgact
     3601 taaagtcagc cgcagtgaat aggcccaagc aactgtttat caaaaacaca gctctctgct
     3661 aaatcgtaag atgatgtata gggggtgacg cctgcccggt gctggaaggt taagaggagt
     3721 gcttagcgta agcgaaggta tgaattgaag ccccagtaaa cggcggccgt aactataacg
     3781 gtcctaaggt agcgaaattc cttgtcgggt aagttccgac ccgcacgaaa ggcgtaatga
     3841 tttgggcact gtctcaacga gagactcggt gaaattttag tacctgtgaa gatgcaggtt
     3901 acccgcgaca ggacggaaag accccatgga gctttactgc agtttgatat tgagtgtctg
     3961 taccacatgt acaggatagg taggagtcta agagatcggg acgccagttt cgaaggagac
     4021 gctgttggga tactaccctt gtgttatggc cactctaacc cagataggtg atccctatcg
     4081 gagacagtgt ctgacgggca gtttgactgg ggcggtcgcc tcctaaaagg taacggaggc
     4141 gcccaaaggt tccctcagaa tggttggaaa tcattcgcag agtgtaaagg tataagggag
     4201 cttgactgcg agagctacaa ctcgagcagg gacgaaagtc gggcttagtg atccggtggt
     4261 tccgtatgga agggccatcg ctcaacggat aaaagctacc ctggggataa caggcttatc
     4321 tcccccaaga gttcacatcg acggggaggt ttggcacctc gatgtcggct cgtcgcatcc
     4381 tggggctgta gtcggtccca agggttgggc tgttcgccca ttaaagcggc acgcgagctg
     4441 ggttcagaac gtcgtgagac agttcggtcc ctatccgtcg cgggcgtagg aaatttgaga
     4501 ggatctgctc ctagtacgag aggaccagag tggacttacc gctggtgtac cagttgtctt
     4561 gccaaaggca tcgctgggta gctatgtagg gaagggataa acgctgaaag catctaagtg
     4621 tgaaacccac ctcaagatga gatttcccat gattatatat cagtaagagc cctgagagat
     4681 gatcaggtag ataggttaga agtggaagtg tggcgacaca tgtagcggac taatactaat
     4741 agctcgagga cttatccaaa gtaactgaga atatgaaagc gaacggtttt cttgaattga
     4801 atagatattc aattttgagt aggtattact cagagttaag tgacgatagc ctaggagata
     4861 cacctgtacc catgccgaac acagaagtta agccctagaa cgccggaagt agttgggggt
     4921 tgccccctgt g
//
LOCUS       DBERPV010000064         4119 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.64, whole genome shotgun sequence.
ACCESSION   DBERPV010000064 DBERPV010000000
VERSION     DBERPV010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4119
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.64"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(311..508)
                     /locus_tag="ACL8C7_001983"
     CDS             complement(311..508)
                     /locus_tag="ACL8C7_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1396111.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFSQLWNPQNPCQILIKKLE"
     gene            complement(493..711)
                     /locus_tag="ACL8C7_001984"
     CDS             complement(493..711)
                     /locus_tag="ACL8C7_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HGS1396112.1"
                     /translation="MKDLPEWFGIPESTQAYIEGTTTLQVWTAYQESDLTGFVRLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            complement(809..1594)
                     /locus_tag="ACL8C7_001985"
     CDS             complement(809..1594)
                     /locus_tag="ACL8C7_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1396113.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            complement(1596..2414)
                     /locus_tag="ACL8C7_001986"
     CDS             complement(1596..2414)
                     /locus_tag="ACL8C7_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1396114.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVIYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            complement(2416..3408)
                     /locus_tag="ACL8C7_001987"
     CDS             complement(2416..3408)
                     /locus_tag="ACL8C7_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS1396115.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYDGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            complement(3793..>4119)
                     /locus_tag="ACL8C7_001988"
     CDS             complement(3793..>4119)
                     /locus_tag="ACL8C7_001988"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1396116.1"
                     /translation="IMVSNLHQNDKINQLISDYKQNMKAFYITIEKFIRDDESLKCYF
                     IKVISSRSKVTSLDQIEADKTIQRKYSSELKNLLDFIMRLFVREIVSYMYERGGRVGL
                     GSRCVS"
BASE COUNT         1377 a          902 c          698 g         1142 t
ORIGIN      
        1 agtccaaaac tttcgttaac cgggatacat tataagcaca ttcataccat caaaaatagt
       61 agcaataaac ttgaacaact accagaaaca cgaaaacagg cataattgat gaaatatcag
      121 cgctattaaa caatataaat aaccgctaag aataaggctt aacggttatc ttctacctat
      181 ctattttttc aactcctcag tcgtttatct acctataacc taggctttac gagtgccttg
      241 ctctaccaac tgagctaaat cggcgattac acttacagta tagcactctg agaatagatg
      301 tcaagtaata ttattcaagc tttttaatca aaatctgaca aggattttgc ggattccata
      361 gctgagaaaa aatctctaac tttttaaagc caagacctcg ataaaagtca tttgttcgat
      421 cataatcttt attagaacct tctgccactg ttttgacctg cagataacca acttttttac
      481 gagcttcact ctctaaagta gcaagcaatt ggctcccaat ttttctacct tgataagctt
      541 ttttacgccg agacaatcaa tctctgcaca atcttcactc gaataggata accttacaaa
      601 tccagtcaaa tcactctcct gataggcggt ccaaacttgc agtgtcgtgg ttccttctat
      661 ataggcttgt gtgctttctg ggattccaaa ccattctggc aaatccttca aaacctcagc
      721 gacaactgcc ttttttgatt ttcatccttg acttcttcaa ttacaaacat cataagttcc
      781 tttcttgatt ttagtcttac tttagctttt acgaacccgc actttcgtag gaatctaagc
      841 ccttatccca aagtttaagg gaaataacaa agaaaaccag agaaatcaac atcaaacctc
      901 ctacgttaaa gaacacatcc ttttcctgta agaaatagct agctggatag taggctgtaa
      961 aggcgaaagg cacgataaag ctaatcaacc aacgaagaag agaattgtaa atagaaatcg
     1021 gatacttagc aaagtcattg aacatataga agatgtaaat catggcgcct gactgcttag
     1081 tccaaaaggc gatactggct gttgcgattt taagagaagt ataaatcaag gtcgcaaaag
     1141 gaatacaaac taggaaaagc aggaattttg gaagagtcca aacaatgctg gtcactgttg
     1201 ttcccaataa aataccaccg actaagagtt cacccaaggc atcaatctga aaggtttcaa
     1261 ctaggatatg aaagagagga ttgatgggac gagtcagata cttgtcaaac tccccttttc
     1321 ggactaggcg ttgccctagt gcccagagat tgtcaaaaaa gagatggtcc attcccttgg
     1381 gaatcaagga aaatccataa atgaaagcta tctcttgaaa ggtccagcct tctaggaatg
     1441 gaatatgttg aaagatgaca ttgagaaaca agagattcaa gccttgagcc agaaagactc
     1501 ccaagacacc aaccacaaaa tccaccttat attccatgat ttgtttgatg tattgtctga
     1561 taaaaatcag atgcattcgt tgatattttt tcatactaac ctccttgaat ggtgataaag
     1621 gactggaccc gtttccaaat caactgagac aatcccacca tcactaagag ccagaagaac
     1681 tgcaaaagga gtgcctgaag aatctgactg gcatcgtatt ttccaacaat gatcataact
     1741 ggagtataaa tcaaggatga aaaaggcaaa aaggagagaa tatctgaaac aacctttgga
     1801 aagaatgcca agggaatcaa actccccgac ataaaagcca ctatggaagt cttaagtagg
     1861 ttggaacccc aaagattttt aaacacaaag gctgaaaatc caaagcaaat attaaagaaa
     1921 aagttaatca gataggcgag cgttaagcta aaaagataaa tgacagttaa tcctagcacc
     1981 tctacaatac cttgacccga tatgattttc atcaagacaa tgacacttaa aaatggaagg
     2041 ccaacgctga taaaaatcaa ccacttggaa ccaagctcgg tgaaaagata ggaggccgca
     2101 aaatgcactg gtcgcaacaa acgcatgata atggagccat ccttgacctc ctccccaatc
     2161 ataaaggacg aatcggatct agtcagaaga ttggtcacaa aactcatgat gatgtagagg
     2221 gtgatatccg ccatactgaa gccctgaatc aaagactctt gcgaagaatc aaagacagcc
     2281 ttccagagat aaaaggccac aaaagccccc atgacatcgc caatccgata gagaataaag
     2341 ttgactcggt aagtaatcaa ctcctgaacc cctgcattga taaagggttt ataacgtctc
     2401 cacaatttga tcatcctaga gctcctttcg gtagaagcga cggataatat cctcaatatc
     2461 cgtatccacc atcttcaaat cgcggatttc aaaatcagac agggtttgct tgataatgtc
     2521 agctgactgg tagcgagaac tatcaaattc aatgttgagg ctgtttcctt gtctatcaat
     2581 ggtcatatca gacagaccgt catagtgaga gacgagatga ctttgacctg gtagcagttc
     2641 aaaagagaga gtcttcatct taccaaaggt ctccttgagt tggctcaccg ttccatcaaa
     2701 aatctcttgc cccttgtcaa tcatgaaaat ccgatcacaa agttgctcaa tatcactcaa
     2761 atcgtgagtg gtcaaaagaa tggtagtttc ttcctcttga ttgatctgag taattgcccg
     2821 acgaatatta tccttaaccg aaacgtccaa accaatggtc ggctcatcta aaaaaagaac
     2881 cttgggattg tggagcaagg aggccgcaat atccgcccgc atccgttgtc ccagtgaaag
     2941 agtccgcacg ggatccttga taaagtcctt caaatccaag acttcattca aaaagtccat
     3001 acgcttatga aagagcgagt ctggcacatc ataaatctct tttaagacag tgtaggtctc
     3061 ttgcagagcc aaatcccacc atagctgggt gcgttgtcca aagactacgc caatatcttt
     3121 gacataatct tgccgattgt cctggggaat cttgccgtta atccgacaaa aaccagatgt
     3181 tggtttcaaa attcctgtca gcattttaat ggttgtcgac ttcccagcac catttgcccc
     3241 gataaatcct aaaatctgcc cttttggaac ctcaaaggtc aaatccttga ccgcttcaaa
     3301 ggtctgcttt tcaggatgaa taaaggagcg caaagccccc ttcaagcccg gttccttaac
     3361 agtcttcaca aaatttttct gaagatgttc cacttctatc attgccatat ctatctccct
     3421 atcgtaagga atagcaacat tgtgttttta actacaaata ttctaaatcc ttactttcta
     3481 caccttctac attttattac tacagaaggc tttataccaa cctattatag tccaataaaa
     3541 aacaaaatgc aagcgtttgc ctatggattg tgaaattagg atttctctca tgaaataata
     3601 cttttaatca aaaattctgt ttaatagttt aaattaccaa cctactcatc ttctcaccag
     3661 agggcggtat taactttgct cataaaatcg gatactccct ctatccagaa aatatgctca
     3721 gaatgattgt ctctaaacaa tacctgctct tttacctcat tcatgaaaaa gaagtccata
     3781 ccctgagaat tatcaactca cgcaccgact acctaaacca actcgaccac ctctttcgta
     3841 catgtaggaa actatttccc tcacaaataa tctcattata aaatccaata aattttttag
     3901 ctcacttgaa tattttcttt gtatcgtttt atcagcttca atctgatcta gacttgttac
     3961 cttggaacga cttgaaataa cctttataaa ataacactta agactttcat catctcgtat
     4021 aaatttttca atagtgatat aaaaagcttt catattctgt ttgtaatcag atattaattg
     4081 attaatttta tcattctgat gaagattcga taccataat
//
LOCUS       DBERPV010000065         4060 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.65, whole genome shotgun sequence.
ACCESSION   DBERPV010000065 DBERPV010000000
VERSION     DBERPV010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4060
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.65"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(173..1588)
                     /locus_tag="ACL8C7_001989"
     CDS             complement(173..1588)
                     /locus_tag="ACL8C7_001989"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGS1396117.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLLGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLGLPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEH
                     DINIEFAAEDAKLLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLEYS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(1601..3439)
                     /locus_tag="ACL8C7_001990"
     CDS             complement(1601..3439)
                     /locus_tag="ACL8C7_001990"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HGS1396118.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTPAITKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVEVGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(3457..>4060)
                     /locus_tag="ACL8C7_001991"
     CDS             complement(3457..>4060)
                     /locus_tag="ACL8C7_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HGS1396119.1"
                     /translation="LGKITLGNNFDEIIYINLTDHISSSIERYKEGVIISNPLRWEIS
                     KYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHFVNANLENNFQESYKITEIIMG
                     IEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVENTTYCDDDDEDLLALMKNKYPR
                     EYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTKNLD"
BASE COUNT         1360 a          808 c          533 g         1359 t
ORIGIN      
        1 ataaccaatc tatcctaagt taactattta taatcggctc tctgtaacaa aattaaatta
       61 atccccctat aaaataaaga ggtttagaat ttgatgtctt ccaaacctct ttatttcata
      121 ttcaatgaga tgttgcctta accgtgataa tatctaatca tcaataaaca aactatttga
      181 ataaggattc tccatttgat tcaatcactc ctttatacca agtaaaggac attttcttat
      241 atcgattgaa tgtgccattt ccatcatcat ttcgatcaac ataaatgaga ccgtacctct
      301 tagaaagttg tgcagtggac atagaaacgc agtcaataca tccccaagac gtatagccca
      361 taatttccac accatcttgt agagcttcag ctacttgcaa taaatgttct ttcatatact
      421 gaattctata atcatcttgg actgttaagt tattaaattc atcttttatt agttgatctt
      481 tagcacctaa tccgttttcc actataaata atggaatttg ataacggtca taatatctat
      541 ttaaaattat acgtagtcca attggatcaa tttgccatcc ccactcagaa tactctaaat
      601 aaggatttac taagccacca ataatattcc cttctcctga attatactgt gttggaagag
      661 cagattgagt cacactcatg taatagctaa aggataaaaa atctacggta taatttttta
      721 ataattttgc atcttcagct gcaaactcta tgttaatgtc atgttcctta aaatatcttt
      781 ttgcataatt cggataataa cctctaacat gcacatctga aaatagataa tttagattct
      841 catactcatg agtcgcccat acatcttttg gatttggagt cattggataa gctggcatag
      901 ctaataccat acaccccacc ttaaactctg aattaatctc acgagcaatt tttgtaacca
      961 aactcgaggc gactaattca tgatgtatag cttgatataa ttcttgtttc gaaagattct
     1021 ccttaggtat atctattcct ccactagtaa acggtaatcc caaaacagag tttacttcgt
     1081 taaatgtaag ccaatattta actttatctt tatacctttc taaaactgtt cgagcaaatt
     1141 tttcataaaa atgaatcatt ctcctatcaa tccatccatg atattttctt gctaaatata
     1201 atggagtctc atagtgtgaa agagttacaa gtggctctat cccgtgagca tgtagttcat
     1261 caaacaattc atcataatat ttcaacccag cttcgttagg ttcttcttca tctccttttg
     1321 gaaaaattct actccatgca atagaagtac gaaaaacatt aaagcccatt tcagaaaaca
     1381 aggatatatc ttccttatat ttatgataaa aatcaatacc taacaatttt aagttatctt
     1441 ctgtaggatt ttctgttgct tctcctaatc cacctttggg taacacatcc tgaactgata
     1501 atcccttacc atcttcatta tatgctccct ctacttgatt agctgcaaca gctccacccc
     1561 aaagaaaatc atctggaaaa atggtcataa ctttcctcca ttataatatt accagtaatt
     1621 ccttagaatg ctcgattgtc tgattattag gtaatactaa tacatctaga aaatcattgg
     1681 tattcgttac aattactggt gtaactgttt cgtagccttt agtcttgatt aaattcaagt
     1741 ccatttcaaa aatcaactga tttttgaaaa ctctgtctcc ttcttctaca tgactaataa
     1801 aaccttgacc ttttagctca acagtatcta atccaatatg aattagtaac tcaacaccct
     1861 catcactctt caatccaatt gcgtgcttag tcggaaaaat atttgtaatt ttcccatcaa
     1921 atggtgcata aaccttacct tcacttggga taatcgctac tccgtctcca attagtttat
     1981 ctgaaaatgt tttatcctgg acatcgctta acggaatgat ttctcctgat ataggagaaa
     2041 atatcatttt tttatttgaa actccaactt caacttctaa attgctagaa ctctcttctt
     2101 catcgattcc aaatatataa gctaatacaa aggtaataac aaccgaaatg accgccacaa
     2161 ttaaagcatt tacaatattt gatggcacat cagaataaat aaattgaggc aacgctatca
     2221 aagatgggac agcaaataga tatgctttaa cactagtaag acctgcaaat aatcccgcta
     2281 atccaccacc aatcatagct gcataaagcg gttttttata ttttaaagtc acaccatata
     2341 atgcaggttc ggtaatccct gcaagtaagg ctgagaaacc tgctgcaaaa gcaatttgtt
     2401 ttgtattatt atttttactc tttaatgcaa cagccatcga agcagcccct tgagctaagt
     2461 ttgaccctaa cattgctgga agaattaata cgtctggagt agcaatagat gccgccaaaa
     2521 aaataggtgc aaaagcccaa tgcattccag tcataacaat aaatggcata atagcaccaa
     2581 gaatagctaa tgtaagccat ccagctacac catacatttg cccaactaga tttgataatc
     2641 cttcaccaac aattactcca ataggtccga ctacaactaa ggcaatacag cttgatacta
     2701 ataatactag cgtaggttgc aaaaaactct tagtaatagc tggtgttaat ttagcaatta
     2761 ttttttcaat atatttcatc aaccaaacca taataagaat tggaacgact gatgaaccat
     2821 aactagctgg tgtcacaggt gcaccaaata aactaagagg attccctgat tgcaccattt
     2881 gaacaaaatt tggatggaga agtacacctg ctacagacat agctaatgta gatgttactt
     2941 ttaatttttg tgatgcagaa taagctaata acagcggtaa gaaataatat ggagcatccc
     3001 caaaaaatgt caaaaaagca atagtctgag aatctgattg caatatacca agcattggta
     3061 aaatgattac caagactttc aacatacctc cccctaacat tgctggaatg attggagtca
     3121 tggaaccagc gatatactca atgattcttt ctaaaatatt ccctttgtgc ccttgaacaa
     3181 ctgaatcgga ttcaaaattg ccaagtttaa cgaattcttt ataataatta gctacatcat
     3241 taccaagtat aatttgatat tgtccattct ttttcataat acctattaca cctggtatct
     3301 tcttcacatc atcatcattg actaaatttt catcttttaa ttctaatctt aaacgtgtta
     3361 cacaatgggt aactctattg acattttttt cacctccaat tacatcgagg attttttgta
     3421 ccgtatcttt ataactcatg gtattctcct attctattaa tctaaatttt ttgttaagcg
     3481 acgaatatga gccatcaaat aaactaattc actagaagtc agcaaataat tgtactccgt
     3541 ttgtataaac attgccacct gttcaccaca ttcatattct ctaggatatt tatttttcat
     3601 taatgctaac aagtcttcat catcatcgtc acaataagtt gtattttcaa ccaagcgatg
     3661 ggcaaataat tttatatgag ttatgaatct ataataatca atagaatctt ggttaaactc
     3721 agtacaatag aaatcttgaa tgattttctc aattcccata attatttcag tgattttata
     3781 cgactcttga aaattatttt ctaaattagc attaacaaaa tgtagcgcta tgaatgcagc
     3841 ttcgtcaatt ggaagttcaa tacctaactc tttttttatt atttgtaaag cccttttccc
     3901 aagctcaaat tcttctttat aatatttcga gatttcccag cgtaggggat tcgaaataat
     3961 aactccttct ttataacgtt ctatactcga agaaatatga tccgttagat ttatatagat
     4021 aatctcatca aaattattac ctaatgttat tttacctaga
//
LOCUS       DBERPV010000066         3503 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.66, whole genome shotgun sequence.
ACCESSION   DBERPV010000066 DBERPV010000000
VERSION     DBERPV010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3503
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.66"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..300
                     /locus_tag="ACL8C7_001992"
     CDS             <1..300
                     /locus_tag="ACL8C7_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1396120.1"
                     /translation="QNRLHNIYKGFTHYKYYRAENSHLIYADYFEMKLKKLLKDDTKV
                     FEKSTFKFVEGYKIYLTESKESGIKQMDNVIKYFEFIESKSIALYFQKRLNELID"
     gene            complement(658..1191)
                     /locus_tag="ACL8C7_001993"
     CDS             complement(658..1191)
                     /locus_tag="ACL8C7_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HGS1396121.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(1280..2056)
                     /gene="recX"
                     /locus_tag="ACL8C7_001994"
     CDS             complement(1280..2056)
                     /gene="recX"
                     /locus_tag="ACL8C7_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HGS1396122.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIIRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPSRALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYSKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            2094..3449
                     /gene="rlmD"
                     /locus_tag="ACL8C7_001995"
     CDS             2094..3449
                     /gene="rlmD"
                     /locus_tag="ACL8C7_001995"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGS1396123.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKENHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT         1161 a          586 c          613 g         1143 t
ORIGIN      
        1 caaaataggc tccataatat ctataaggga tttacccact acaaatatta tagagccgaa
       61 aattcacatc taatatatgc agactacttt gaaatgaaat taaaaaaatt attaaaggat
      121 gacacaaaag tttttgaaaa atctacattc aaatttgtag aaggatataa aatatacctg
      181 acagaatcta aagaatctgg aattaaacaa atggacaatg tcataaaata ttttgagttt
      241 attgaatcta aaagtattgc tttatatttt caaaaacgat taaatgagct gatagattaa
      301 atagcatttt ctctgttgag atattgtttt taaaatattg tactaaatga ttgatgctat
      361 gtggaaatac aaaaaaatgt ttttgatacg aagttgacct gtatttttta tactaatcat
      421 tttcgtattt tttgtattaa acgatataag tttgttgtaa acttacaagg aataaagaca
      481 ttaaaaaata atagtatatc tatttgtttt atatatttta cgaattctgc ataaatctct
      541 ttctagtaat gtgttgtaac tctgctataa tggatttatt cctttttgtg tttacacaat
      601 ttattttata ctaccaaaaa aacaaggtca ggattttgtt cctgaccttt gacaacttta
      661 ccgattcttt agttctacat agcgcttgta ccaaatgttt acataggctt ctgagaaagg
      721 accacgtcca ttgttaatcc aatcaacaag aattttgaca tgttctttta aaatatagtc
      781 caagtcatca gaataattca ttttgcgttt gtgacgctcg tactcttcaa cgtccaagag
      841 acgtttttcc ccatctgtaa aaattttaac atccaaatcg taatcaatat acttcagtgc
      901 ttcttcatcc agatagtagg ggctagccat attgcaatag taagaagttc cattatcacg
      961 aatcatggca atgatattaa accaatattt cttgtgaaag taaacaatag ccggttctcg
     1021 agtgacccaa cgacgaccat cactttcggt aacaagtgta tgatcgttga caccaataat
     1081 ggcgttttct gttgttttta gtaccatggt gtcccgccaa gttcggtgga gactcccatc
     1141 atgcttataa ctttgaattg taataaagtc gccttctttt ggaagcttca taactaacca
     1201 actttctaca atttataagt ttatcattta ctattgtacc ataaaattac ctaaaatctg
     1261 tgaatttcac ttggaaatat taaagatatt ctctaagagc gcttgctata tccgaaaaat
     1321 cgtagccctt tcgtgctaaa acttgagtta aacgctgctt cagttcgtat ccttcatact
     1381 ttcgagcata cttactatat tgtttatcaa gttccttgaa gatgagttct tgagtcgttt
     1441 cttggtcaac ttggctatct aagtcgtcaa aggcaatttt agcatcagaa taagagaagc
     1501 ccttgttagt caagttctgg ataatcttat cttgcagggc acgagatgga agttttccct
     1561 catatttttt caatagttta ttagctacac gttgagcaac ttcagaaaaa tcaaattctt
     1621 tcaagttctc ttctatagta gattttgaaa tccctttttg agctagtttc tgagtcagca
     1681 cataaggacc cttgtctcct gaaagttgat tggtattgat gatagcataa gcgtactgac
     1741 catcattaat ccacttatct tctttaagat tagcaataac ttgagaaacg atgtttttat
     1801 caatatcgta ttttttcaga tattctctga cctctttttc agtacgtgct ttaaaggata
     1861 agtggtagag ggccagattc ttaccataag aaaattgagc aaagtcttga atctctttca
     1921 attcctcttc gcttatcacc ttatctctcg ataacataaa acgaataatt gtgtcttcgg
     1981 tgatatagca tttgtcgcca ttatcaagct ccatcagata gagtcttttt ttcttttcaa
     2041 gttttgtgat tttcatagct ctattataac tcaaaatgtg ataagatagg ggtatgaatc
     2101 tgaaagtgaa acaaaaaata ccattaaaaa tcaagcgcat gggaattaac ggtgagggaa
     2161 tcggctttta ccaaaaaaca ttagtctttg taccaggagc tctcaaaggc gaagatatct
     2221 attgtcagat tacttctatt agacgcaact ttgttgaagc aaaattactg aaggtcaaca
     2281 agaagtctaa atttcgaatt gtgccatctt gtactattta taatgaatgc ggaggctgcc
     2341 aaatcatgca cctgcattat gataagcagc tggagttcaa gacggactta cttcatcaag
     2401 cgctgaaaaa atttgctcct gcaggatatg aaaattatga aattcgtcca actattggaa
     2461 tgcaggaacc aaaatattac agagctaagt tacaatttca gactcgaaaa tttaaaaatc
     2521 aggtcaaggc gggcttatat gcacaaaact ctcactattt agtagagttg aaagactgcc
     2581 tggtacaaga taaggaaacc caagtgattg ctaatcgctt agcagaatta cttacttatc
     2641 accagattcc aatcacggat gagagaaaag ttctaggtgt ccgtactatt atggtccgac
     2701 gcgcgagaaa gaccggacag gttcagatta ttattgttac aaaccgccag cttaatttaa
     2761 ctcaattggt aaaagagttg gttaaagatt tcccagaagt tgtgacagta gctgttaata
     2821 caaatacagc taaaaccagt gagatatatg gtgaaaagac agagattatc tgggggcaag
     2881 agagtattca agaaggtgta ctcaattatg aattttcact atcccctcga gctttttatc
     2941 aactaaatcc tgagcaaaca gaagtcctct atagcgaagc agtaaaagcg ctggatgttg
     3001 ataaagaaaa ccatttgatt gacgcttatt gtggagttgg aacgattgga tttgcctttg
     3061 caaagaaagt aaaaacactc agaggtatgg atattattcc agaagctatt gaagatgcca
     3121 agcgaaatgc taaaagaatg ggatttgaca atactcatta tgaagctgga acggcagaag
     3181 agattattcc tcgttggtac aaggaaggct accgagcaga tgctttgatt gttgacccac
     3241 cacgtacagg tctggatgat aagttattag atactattct tacttatgta ccagaaaaaa
     3301 tggtttatat ttcttgtaat gtttcgacct tggctcgtga tttggtacgc ttagtagaag
     3361 tctatgatct tcattatatt cagtcggtcg atatgttccc acatacagct cgaactgaag
     3421 ctgttgtaaa attaataaaa aaagtttaaa aaaggtgttg acaaagtttg aaaagactgt
     3481 ataatagtaa gagttgaaaa taa
//
LOCUS       DBERPV010000067         3418 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.67, whole genome shotgun sequence.
ACCESSION   DBERPV010000067 DBERPV010000000
VERSION     DBERPV010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3418
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.67"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..147)
                     /locus_tag="ACL8C7_001996"
     CDS             complement(<1..147)
                     /locus_tag="ACL8C7_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HGS1396124.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSL"
     gene            375..902
                     /locus_tag="ACL8C7_001997"
     CDS             375..902
                     /locus_tag="ACL8C7_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HGS1396125.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIISLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            979..1335
                     /gene="glnR"
                     /locus_tag="ACL8C7_001998"
     CDS             979..1335
                     /gene="glnR"
                     /locus_tag="ACL8C7_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HGS1396126.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            1372..2718
                     /gene="glnA"
                     /locus_tag="ACL8C7_001999"
     CDS             1372..2718
                     /gene="glnA"
                     /locus_tag="ACL8C7_001999"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HGS1396127.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYVAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(2814..2933)
                     /locus_tag="ACL8C7_002000"
     CDS             complement(2814..2933)
                     /locus_tag="ACL8C7_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HGS1396128.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            2898..3047
                     /locus_tag="ACL8C7_002001"
     CDS             2898..3047
                     /locus_tag="ACL8C7_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope"
                     /protein_id="HGS1396129.1"
                     /translation="MEKFNFKNNIGQENKLLQIEIYKFTNFCKLQNYTSVNIFSKDIF
                     EAIVN"
     gene            3191..3328
                     /locus_tag="ACL8C7_002002"
     CDS             3191..3328
                     /locus_tag="ACL8C7_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1396130.1"
                     /translation="MNPDRAEEYFCRGCQGENPEDIEFYDEQLQAEKVEALNIRLEVK
                     N"
BASE COUNT         1043 a          597 c          691 g         1087 t
ORIGIN      
        1 tagacttcca caatcagggc aagatggagc ctcataatcc agcttagcga taatttcttt
       61 gtgggtatcc atattgatga tatctagaat cttgatgttt gggtctttaa tatcgagcag
      121 ttttgtgata aaatgtaatt gttccatatg aatctttcta atgatggttt tgtcgctttt
      181 cattataggt catatgggac tttttttcta caataaaata ggctccataa tatctatagt
      241 ggatttaccc actacaaata ttatagagcc tgaaagttcc tcttttcttt tgcttaaaat
      301 aaaaacgctt cctctcaact attactcata aaaatcaccg atttatgata aaatggaaat
      361 agaaagttga gattatgagt tattttaaaa aatataaatt cgataaatcc cagttcaaac
      421 ttggtatgcg aacctttaaa acaggtattg ctgtttttct agttctcttg atttttggct
      481 tttttggctg gaaaggtctt caaattggtg ctttgacagc cgtttttagc ctgagggaga
      541 gttttgatga gagtgttcat tttgggactt cgcgtattct aggaaatagt atcggtggac
      601 tctatgcctt ggtcttcttc ttattaaata cctttttcca tgaagccttt tgggtgacct
      661 tggtagttgt tccaatctgc accatgttaa ccattatgac aaatgtagcc atgaataaca
      721 aagcaggggt tattggtggt gtagcagcta tgttaatcat tagcctatca attccaagtg
      781 gtgagacaat ttcgtacgtg tttgtacgtg tatcagaaac gtttatggga gtttttgtcg
      841 caattatcgt aaattacgat attgatcgta ttcgtctctt tttagagaaa aaagaaaaat
      901 aatgttacat tttataacat tatcaattga cgtttgtctt tttttagact ataatagaca
      961 gaaagaagga aattgtaaat gaaggaaaaa gaatttcgcc gaaatatggc tgtttttcct
     1021 atcggcagtg ttatgaagtt gaccgatcta tcggcgcgtc agattcgtta ttatgaagat
     1081 caagagttga tcaagcccga tcgaaacgaa ggaaatcgtc gcatgtattc cttgaatgac
     1141 atggatcgtc tgcttgaaat caaagattat atctctgaag gttataatat cgctgccatt
     1201 aagaaaaaat atgctgaacg tgaagcgaaa tccaagaaag cggttagtca gactgaagta
     1261 cgtcgtgcac ttcacaatga actcctccaa caggggcgtt ttgcttcagt acagtcacct
     1321 tttggtcgcg gttaggcaac cgcaagtagt catagattaa ggagaaaact tatgccaatc
     1381 acagctgcag atattcgtcg tgaagtcaag gaaaaaaatg ttacctttat tcgtcttatg
     1441 ttctcagata ttttgggaac catgaaaaac gtcgaaattc ctgctacaga tgaacagtta
     1501 gataaggtct tgtcgaacaa ggttatgttt gatggatctt ctattgaagg ttttgtacgt
     1561 atcaatgagt cggatatgta cttgtacccg gacttggata catggacagt cttcccttgg
     1621 ggagatgaaa atggaagtgt tgcaggtctg atctgtgatg tctatacaac agaaggtgaa
     1681 ccatttgcgg gtgaccctcg tggtaatttg aaacgagctc ttcgtcacat ggaagaagtt
     1741 ggattcaaat ccttcaacct tggtccagag ccagaattct tcctatttaa gttggatgaa
     1801 aatggggacc caacacttga agtgaatgac aagggtggct actttgattt ggcacctact
     1861 gaccttgcgg acaacacacg tcgtgagatt gtgaatgtct tgaccaaaat gggatttgaa
     1921 gtagaagcga gtcaccacga ggttgcggtt ggacagcatg agattgactt taagtacgat
     1981 gaagttctcc gtgcttgtga taagattcaa atctttaagc ttgttgttaa aaccattgct
     2041 cgcaaacacg gactttacgc aacatttatg gcgaagccaa aatttggtat tgctggatca
     2101 ggtatgcact gtaatatgtc cttgtttgat gcagaaggaa ataacgcctt ctttgatcca
     2161 aatgatccaa aaggaatgca gttgtcagaa acagcttacc atttcctagg cggtttgatc
     2221 aagcatgctt acaactatac tgccatcatg aacccaacag ttaactcata caaacgtttg
     2281 gttccaggtt atgaagcgcc tgtttacatt gcttgggctg gtcgtaaccg ttcgccactt
     2341 gtgcgcgtac ctgcttcacg tggtatggga actcgtcttg agttgcgttc agtggatcca
     2401 atggcgaacc cttacgttgc tatggctgtt cttttggaag ttggtttgta tggtattgaa
     2461 aataaaatcg aagcaccagc tcctatcgaa gaaaatatct acatcatgac agcagaagag
     2521 cgcaaggaag ctggtattac agaccttcca tcaactcttc acaacgcttt gaaagctttg
     2581 acagaagatg aagtggttaa agctgctctc ggagatcaca tctatactag cttccttgaa
     2641 gccaaacgaa tcgaatgggc aagttatgca accttcgttt cacaatggga aattgataat
     2701 tatttagacc tttactaata ctaatataga agaaagattg cctgtgggta aacagtcaca
     2761 cagcagtcta agccatcaaa tacctataac ccttaaaata gcgatttcgg tcgctattta
     2821 tttttcgaaa aatcctcttg actcttttgc gaattagatt tatcatcaga cgtgtagaag
     2881 aaaattaagg agtcactatg gaaaaattca atttcaaaaa caatatcggg caagaaaaca
     2941 agttacttca aatcgaaatc tacaagttta ctaacttttg caagcttcaa aattacacat
     3001 ctgtaaatat tttttcgaaa gatatatttg aagccatagt aaattgagac tagaatagta
     3061 cactacatct gctaaaaatt tctagaaact aatttaactt tcctaatcga tttgtttaca
     3121 tcttatttca atctactata ttatctcaat aaatgatgat ggcgactgtt ttgtttgtgc
     3181 ttgtcgattt ttgaatcctg atcgagcgga agaatatttc tgccgaggtt gtcaagggga
     3241 aaatcctgaa gatattgaat tttatgatga acaattacag gcagaaaagg tggaggcttt
     3301 gaatattcga ttggaagtaa aaaattgaat tatctacaat ctcatcaaca ataaacctat
     3361 ttcaacccca ttatctatag gcgtattttt acgccttttt atatacttga agcacata
//
LOCUS       DBERPV010000068         3411 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.68, whole genome shotgun sequence.
ACCESSION   DBERPV010000068 DBERPV010000000
VERSION     DBERPV010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3411
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.68"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..1316
                     /locus_tag="ACL8C7_002003"
     CDS             <1..1316
                     /locus_tag="ACL8C7_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS1396131.1"
                     /translation="PDTWEWVRFSTLVEIVRGGSPRPIKDYLTSEVDGINWIKIGDTE
                     KGEKYINNVKEKIKKSGLNKTRFVKKGTFLLTNSMSFGRPYILNVDGAIHDGWLAISN
                     YENSLNKDYLFYILSSNVVYSQFLSLISGAVVKNLNSDKVASILIPLPPLSEQQRIVE
                     AIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPNDESVEVLLE
                     KIRAEKQKLFEEGKIKKKDLDISIVSQGDDNSYYGNIPMNWVVIKIKDIFSINTGLSY
                     KKGDLSINNKGIRIIRGGNIKPLEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTS
                     LEHIGKFARIDKDYDGVVAGGFIFQLTPFESSEIISKFLLFNLSSPLFYKQLKAITKL
                     SGQALYNIPKTTLSELLIPLAPFEEQELITQKVEKLFEKVNQLWK"
     gene            complement(1264..1872)
                     /locus_tag="ACL8C7_002004"
     CDS             complement(1264..1872)
                     /locus_tag="ACL8C7_002004"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS1396132.1"
                     /translation="MVKLTTCYFCDYGSYYGNKDETTSYPIYEIPEAWRYIKFASLVN
                     FRIGKTPPRSEATFWGTEIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTL
                     LMSFKLSIGKVAILDIPATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAI
                     KGKTLNSTSISELLIPISNHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(1883..2680)
                     /gene="psrA"
                     /locus_tag="ACL8C7_002005"
     CDS             complement(1883..2680)
                     /gene="psrA"
                     /locus_tag="ACL8C7_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HGS1396133.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            complement(2737..>3411)
                     /locus_tag="ACL8C7_002006"
     CDS             complement(2737..>3411)
                     /locus_tag="ACL8C7_002006"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS1396134.1"
                     /translation="VLLEKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNSYYEEVPCE
                     IPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCNQWSGFSIDLARFIDPETVH
                     SYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYGWAVADSHVTVIRVLSGVINCH
                     FIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIPLPPLPEQSRIVDKIEQFFA
                     HIDALI"
BASE COUNT         1164 a          547 c          527 g         1173 t
ORIGIN      
        1 ttcctgatac ttgggagtgg gtgaggtttt ctacattggt tgaaattgtc agaggtggct
       61 ctccacgacc aatcaaagat tatcttactt ctgaagtaga tggaataaat tggataaaaa
      121 taggtgatac tgaaaagggt gaaaagtata taaataatgt taaagaaaaa atcaaaaaat
      181 cagggcttaa caaaactaga tttgtaaaaa aaggtacatt tttgttaact aattctatga
      241 gttttggtag accttatatt ttgaatgttg atggtgcaat acacgatgga tggttggcta
      301 tttcgaacta tgaaaactca ttaaataaag attacctatt ctatattctt tcatcaaatg
      361 tagtttattc tcaatttcta tctctaatta gtggagctgt tgtgaaaaac ttgaatagtg
      421 ataaagttgc ttctattctt atccctctcc ctccactatc cgaacaacaa cgaatagtag
      481 aagcaatcga atcagcttta gaaaaagtag atgaatatgc tgaaagttat aatagactag
      541 aacagctaga taaagaattt ccagataaac taaaaaaatc tattcttcaa tatgctatgc
      601 aaggaaaatt agttgaacaa gacccaaatg atgaatcagt cgaagtttta cttgaaaaaa
      661 tacgagcaga aaaacaaaaa ctctttgaag aaggcaagat taaaaagaaa gatttggaca
      721 tttctattgt ttcccaagga gatgataact cttattatgg gaatatacct atgaattggg
      781 ttgttataaa aataaaagat attttttcaa taaatacagg tctttcttac aagaagggcg
      841 atttaagcat taataataaa ggtattagaa ttatacgtgg tggtaatatt aagcctttag
      901 aattttctct gttggataat gattactaca ttgatacaca attcatctcc tctgagcaag
      961 tttatttaaa acataatcag ctaataacac ctgtatcaac ctctttagaa catattggaa
     1021 agtttgcaag aatcgataaa gactatgatg gtgttgtggc tggtggattc attttccaat
     1081 taacaccatt cgaaagttca gagattattt caaaatttct attatttaac ttgtcctctc
     1141 cgttatttta taaacaattg aaagcaataa ctaaactatc aggtcaagct ttatataata
     1201 ttcctaaaac tacactaagc gagctattaa ttccgttagc tccttttgag gaacaggaac
     1261 ttattactca aaaagttgag aaactttttg aaaaagtaaa tcaactttgg aaatgattct
     1321 tttcatctct tcatgattag aaatagggat taataattcg gagatactgg tactatttaa
     1381 tgttttccct ttgatagcat cttttgaatc acctaaagta gagataagtg gcaaaaatat
     1441 cattaagtaa tctctgataa tattttcttt attagcatag gggaatatcg atataatggc
     1501 ttcattatga gtggcaggaa tatccaatat ggcaactttt ccaatagata atttaaagct
     1561 cattaataaa gttcctttag gtgaaatgtc tattttcttt gattttaatg ctaatttaga
     1621 aatagattct ctcgtattag ttacataacc agatataggc atatctgata tagataccca
     1681 gggtatttca gttccccaaa aagtagcttc actgcgtgga ggagtttttc ctattctgaa
     1741 gttaactagg ctagcaaatt taatatatct ccatgcttct gggatttcat atataggata
     1801 agaggttgtt tcgtctttat tcccataata agagccataa tcacaaaaat agcaggtagt
     1861 cagtttgacc acctgttatt ttttaccaat taacaatttt atctacaata ttttgttgtt
     1921 cagtagctgt tttccttaga taaattcgag tagtttctat actttcgtgt cccatcaaat
     1981 ctgcaagcaa ggcaatatca ttatacttcg ctaaaaaatt cttagcaaat aaatgcctaa
     2041 aagaatgagg gtaaattact ttaggattca ttttgtattt atcagcataa ttttttaact
     2101 gttgagcaac tcctcttgct gtaattggtt cgttaaattt attcaaaaat aaataaccac
     2161 ttcggcgatt ttctgattct aaccaactaa gacaactatt tcttaatttt ttaggaatgt
     2221 acagtctacg aattttacca ccttttgagt aaatgtcaaa ataaccgatt tctacatgct
     2281 ctacttttag tttaataagt tcacttacac gagccccagt tgcacctaaa aaccaaacga
     2341 caaaatgcca ttttaaaata ccatcttttt tcaaactacg tttaagaaaa aggtaatcag
     2401 catggctaat gacatcttct aaaaacggtt tttgctgtac tttgacaaat tttaatttca
     2461 aatcatcatg accaataaaa gccagatatt tatttactcc ttgtagtcgc aaattgacag
     2521 ttttaggttt aaaattgtct aataaatatc ctttgtattc aaataaatct tccattttga
     2581 gttcgtaatt ctccaagaaa aatcgaacac cataaaggta cgaacgcaca gtattttcag
     2641 ctaaaccagc tttcttcaaa tgtaattcaa aatctttcaa cgtaaaactc ctatcttatg
     2701 tttgatagaa attccaccgc acgtaaaact attatactaa attagtgcgt caatatgggc
     2761 gaaaaattgt tcgattttat caacgattct ggattgttca ggaaggggtg ggagggggat
     2821 taaatattct tttatagttt tcgttaataa ttctttttgt tttgtactac ccgacgcttt
     2881 ttcttcaata actgactgaa caataggaga ggaaagaaaa ttatagatga aatggcaatt
     2941 aataactccc gataagactc ttataactgt aacatggcta tctgcaacag cccagccata
     3001 aggattttta ttttcatggt aaatagctaa tcgtcctaac gtacctagac ctgttgaatt
     3061 ccacattaaa tcaccatctc ttagtaatct ttctttctgg taactatgaa ctgtttcggg
     3121 atcaataaat cttgctaagt caatagaaaa gccagaccat tgattacatt tctgagcaat
     3181 cacagggtat ataggaatat ttgaatattt tggagacttc cctctttgaa tgtaggaggt
     3241 tatatcgttt aacctcaccc attcccaact ttctggtatt tcacaaggta cttcctcata
     3301 ataagagtta tcatctcctt gggaaacaat agaaatgtcc aaatctttct ttttaatctt
     3361 gccttcttca aagagttttt gtttttctgc tcgtattttt tcaagtaaaa c
//
LOCUS       DBERPV010000069         2945 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.69, whole genome shotgun sequence.
ACCESSION   DBERPV010000069 DBERPV010000000
VERSION     DBERPV010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2945
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.69"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(85..1026)
                     /locus_tag="ACL8C7_002007"
     CDS             complement(85..1026)
                     /locus_tag="ACL8C7_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGS1396135.1"
                     /translation="MKQTKRIKRWRYYLCRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(1004..2767)
                     /gene="aspS"
                     /locus_tag="ACL8C7_002008"
     CDS             complement(1004..2767)
                     /gene="aspS"
                     /locus_tag="ACL8C7_002008"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HGS1396136.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEALAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
BASE COUNT          857 a          691 c          593 g          804 t
ORIGIN      
        1 agatagaact gacgaagtca gtaacatata tacggcaagg tgaagctgac gtggtttgaa
       61 gagattttcg aagagtatta atcactaatt atctatctca acaaatcttc ctagaatatg
      121 aacattttcc gagacagaga caaaggagct tggatccact tgtgtcataa tctgtttaaa
      181 ttcattaaac tctgcacgtg taatgacagt gattaaaact gcctttctct cgtgattata
      241 ggttccttct gcatcgtgga tcatggttgc tccgcggtgc aattttttat ggattttttc
      301 aattaccttc tctggatgat ttgtcacaat catggcctgc atacgctttt gcttagtaaa
      361 gactgcgtct gtcacacggc tagagacaaa gatggtaatc atagaataaa gagcgtattt
      421 ccaaccaaag gtcaaacctg ctatcagcat gatagttcca tttaccaaga aagaaatact
      481 accgacattc ttacccgttt tcttgcgaat agtcaggctg acgatatccg tcccaccact
      541 ggagatattg tttcgaagag caaaaccaat ccccaaaccc ataacaacac ccccaaaaag
      601 ggaattgata atgggatcct ccgtcaaggt tgccacaggg acaaactgga taaagaagga
      661 actcatagat accgtgataa aggtaaagac ggtgaactta tggccaatct gataccaagc
      721 taagaccatc aaagggaagt taatggcgta gaagcttagc gaaatcggaa tatgaaaacc
      781 aaaccagtga ttactcaagg cagagataat ctgtgccaga cctgttgcac cactcgaata
      841 cacatgccct ggttggaaaa agaaattaac tgctactgct gataaaaaac catagaccag
      901 agaggccgaa atcttctcat catacttttc tcgagagata ctttgtaaga cacgtaaaat
      961 ttttatctga taagcaaagc ggcacagata atagcgccac cgcttaattc gttttgtttg
     1021 tttcatcttc ttctacttgt aagctgagtt cctctagttg tttgagagcg actgttgatg
     1081 gagcttgtgt cattgggtca gttgccttgt tgttcttagg aaaggcaatg acttcacgga
     1141 tattttcttc tccagcaagc aacatgacaa aacggtcaag cccgatagcc aaaccaccgt
     1201 gtggtgggaa accatagtcc atggcttcaa gaaggaaacc aaactggtca ttggcttctt
     1261 cagctgagaa accaagagcc ttgaacatgc gttcttgaag gtctttttgg ttgatacgaa
     1321 ggctaccacc accaagctca taaccgttca agacgatatc gtaagcaatg gcacgaacct
     1381 tagccaaatc accttctaat tcgtgagcag tctcttcctg tggaagtgtg aatggatggt
     1441 gggcgctcat gtagcggcct tcttcttcag accattcaaa catcggccag tcaaccaccc
     1501 aaaggaagtt gaacttatca ttatcaatca agccaagctc tttagcaata cgtccacgaa
     1561 gggcacccag tgttgcatta gccacttcaa gcgtatccgc cacaaagaga accaagtcct
     1621 tatcttcaag agcaagcgct gttgtcaatt cttcttggat accagtcaag aacttggcaa
     1681 ctggtccgtt taattctcca tcaaccacct tgacccaagc aagacctttg gcaccatact
     1741 gtttggctac ttccgtcatc ttgtcgatgt ctttacgtga atagttgtcc gcagctcctt
     1801 tgaccacaat cgcttttaca gcaagtgctt ctgaaaagac tttaaagtct acacctttga
     1861 ccacttctgt caagtcctga agcaacatgt caaaacgagt atctggcttg tcagaaccgt
     1921 aaagagccat agcatcatcg tatttcatac gagggaacgg tagcgttact tcgatgcctt
     1981 ttgtttcctt catcacgcgc gcgatcaagc cttctgtaat atcttggatt tcttgctcag
     2041 taaggaagga cgtttccaag tcgacctgag taaattcagg ctggcggtct ccacgcaagt
     2101 cctcgtcacg gaaacattta acgatttggt agtaacggtc aaaaccagca ttcatcaaga
     2161 gctgtttcgt gatttgtgga ctttgaggaa gagcgtaaaa atgcccctta ttaacacgag
     2221 acggcactaa ataatcacgc gccccttcag gcgttgactt agaaaggaat ggtgtctcca
     2281 cgtcgataaa ctccaactca tccaagtagt tgcggataga gtgggtcacc ttggcacgaa
     2341 gtttaagatt ttccaacatt tctggacgac gaaggtcaag gtaacggtaa cgcaaacgtg
     2401 tatcgtcatt tgcctcaatg ccatccttaa tctcaaatgg tgttgtctta gctgtgttaa
     2461 gcacaataag agctgtcacg tttaactcaa ccgcaccagt tggcaactta tcattggctt
     2521 gctcacgcgc agcgacctga ccagtcacct caataacaaa ttcgctacga aggctttcag
     2581 ctgttgccat aacctctgca gatacttttt cagggttgat aaccaactgc atgattcctt
     2641 cacggtcacg aagatcgata aagatcaaac caccaaggtc acgacgacgg ccaacccatc
     2701 ctttcaaggt tatttcttgt ccgatgtgtt cctcacgaac acgaccagca tacatactac
     2761 gtttcattat ttctctcctc ttttattctg ttactatttt accataaaag cgcaggctct
     2821 tcatgaaaat catcagaaaa gtttgccagt ctttaaaagt caggtgaaag ccctaaaaat
     2881 tagcgctaat gctcttcgaa aatctcttca aaccacgtca gcgtcgcctt accgtaggta
     2941 tggtt
//
LOCUS       DBERPV010000070         1662 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.70, whole genome shotgun sequence.
ACCESSION   DBERPV010000070 DBERPV010000000
VERSION     DBERPV010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1662
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.70"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            145..1491
                     /locus_tag="ACL8C7_002009"
     CDS             145..1491
                     /locus_tag="ACL8C7_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HGS1396137.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTDYACKELSADAYFPKLLEGGQL
                     ASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEG
                     VAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFR
                     MDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSET
                     LYQAGSWSHKRRVCQFSERKEGNLFYDVISLITNMTSGTSQDQFQLYRGRGQAENFIK
                     EMKEGFFGDKTDSSTLIKNEVRMMMSCIAYNLYLFLKHLAGGDFQTLTIKRFRHLFLH
                     VVGKCVRTGRKQLLKLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPRRKASLMMH"
BASE COUNT          489 a          361 c          327 g          485 t
ORIGIN      
        1 ctaaaaacca tccagaatcc ttgccttagc ttagatcctg gatggtttct tttttcaccc
       61 aatgggtgtt ttttactaga caaaaaagag tttccccttt atggtataag tgtagaaaaa
      121 aacacaaaaa gaaaggaaac tcacatgaac agtttaccaa atcatcactt ccaaaacaag
      181 tctttttacc aactatcttt cgatggaggt catttaaccc agtatggtgg tcttatcttt
      241 tttcaggaac ttttttccca gttgaaacta aaagagcgga tttctaagta tttagtaacg
      301 aatgaccaac gccgctactg tcgttattcg gattcagata tccttgtcca gttcctcttt
      361 caactgttaa caggctatgg aacggactat gcttgtaaag aattgtcagc tgatgcctac
      421 tttccaaaat tgttggaagg agggcagctt gcttcacagc caaccttatc ccgttttctt
      481 tccagaactg acgaggaaac agtccatagt ttgcgatgcc tcaaccttga attggtcgaa
      541 ttctttttac agtttcacca gctaaaccaa ctcattgtag atatcgattc tacccatttc
      601 acaacttatg gcaagcaaga aggtgttgct tataacgccc actatcgtgc tcatggctat
      661 catcctcttt atgctttcga ggggaagaca ggttattgtt tcaatgccca gcttcgtcct
      721 ggtaatcgtt attgttctga agaggcagac agctttatca cacctgtttt agaacggttt
      781 aatcaacttc tctttcgaat ggatagtggc tttgcgaccc ccaaattata cgatttaatt
      841 gaaaaaacag ggcaatacta cctcataaaa ctcaagaaaa atactgttct gagccgtctt
      901 ggagaccttt ccctcccttg cccacaggat gaggacttaa ccatcttgcc ccactccgcc
      961 tactcagaaa ctctctatca agcaggatct tggtcgcaca agcgtcgtgt ctgccagttc
     1021 tctgaacgaa aagaaggaaa cttgttctac gatgttattt ctctcattac aaatatgacg
     1081 agtggaacaa gccaagacca gtttcagctt tatcgtggac gtggtcaagc cgagaatttc
     1141 atcaaggaga tgaaggaggg attttttggc gataaaacgg atagttcaac cttaatcaaa
     1201 aacgaagttc gtatgatgat gagctgtatc gcctacaatc tctatctttt tctcaaacat
     1261 ctagctggag gtgacttcca aactttaaca atcaaacgct tccgccatct ttttcttcac
     1321 gtggtaggaa aatgtgttcg aacaggacgc aagcagctcc tcaaattgtc tagtctctat
     1381 gcctattccg aattgttttc agcactttat tctaggatta gaaaagtcaa cctgaatctt
     1441 cctgttcctt atgaaccacc tagaagaaaa gcgtcgttaa tgatgcatta aagaacagtc
     1501 gagatgaaaa aatcgtgtga cgcaccaagg gaggagtctg cccttttgag gaaatctagc
     1561 gaggaaaaac gatactggaa cagcagaaag taaaactgac ctcatgagga ggaagaaagt
     1621 ggctcatgag gtcaggggtt tggtaagtta catctagttg ag
//
LOCUS       DBERPV010000071         1445 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.71, whole genome shotgun sequence.
ACCESSION   DBERPV010000071 DBERPV010000000
VERSION     DBERPV010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1445
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.71"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..224
                     /locus_tag="ACL8C7_002010"
     CDS             <1..224
                     /locus_tag="ACL8C7_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS1396138.1"
                     /translation="FQTVFKTFLKNKEKIVNALQLPYSNAKLEATNNLIKLIKRNAFG
                     FRNFENFKKRIFIALNIKKERTKFVLSQA"
     gene            320..1445
                     /locus_tag="ACL8C7_002011"
                     /pseudo
     CDS             320..1445
                     /locus_tag="ACL8C7_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          476 a          314 c          227 g          428 t
ORIGIN      
        1 tttttcagac tgtctttaaa acctttctaa agaacaaaga gaaaatcgtc aacgcccttc
       61 aactacccta ttcaaacgcc aaattggaag cgaccaataa tctcatcaaa cttatcaaac
      121 gcaatgcctt tggttttcga aactttgaaa acttcaaaaa acggattttt atcgctctga
      181 acatcaaaaa agaaaggacg aaatttgtcc tttctcaagc ttagcttttc ttcaacccac
      241 tacagttgac aaagagccaa aaaaagtccc ataagatcta taatgaaaag cgaccaaaca
      301 actcattaga aagattcata tggaacaatt acattttatc acaaaattac tagacattaa
      361 agaccctaat atccagattt tagacatcat caataaggat acacacaagg aaatcatcgc
      421 caaactggac tacgacgccc catcttgccc tgagtgcgga aatcaattga agaaatatga
      481 ctttcaaaaa ccttctaaaa ttccttatct tgaaacgact ggtatgccta ctagaattct
      541 ccttagaaag cgtcgattca agtgctatca ctgttcaaaa atgatggtcg ctgaaacttc
      601 tatcgtcaag aaaaatcacc aaatccctcg tatcatcaac caaaagattg ctcaaaagtt
      661 aattgaaaag atttctatga ctgatattgc ccatcagctt ttcatctcaa cttcaactgt
      721 tattcgtaag ctcaatgatt ttcactttaa acatgatttt tcttgtcttc ctgagattat
      781 gtcttgggac gttgaaacag tccgggtagt gactgtttca atcgggagat ggagatgagc
      841 tttattgcgc aagattttga caagctcaat atcatcactg ttcttgaggg aagaacacaa
      901 gctatcattc gaaatcactt tcttaaatat gatagagccg tccgatgtcg cgtcaaaatc
      961 attactatgg atatgtttag cccttactat ggcttggcta aacagcttcg ctttcaaatt
     1021 tctaggctca ggctgaaaca gtctcccaga ctgtttcact cccgaatgct aaaatcgttc
     1081 ttgatcgctt tcacattgta caacatctta gccgtgctat gagtcgtgtg catgtccaaa
     1141 tcatgaatca gtttcatcgc aaatcccatg aatacaaggc tatcaagcgc tactggaaac
     1201 tcattcaaca ggatagccgt aaactgagtg ataaacgttt ttatcgtcct acttttcgta
     1261 tgcacttaac caataaagag attttaaaca agcttttgag ttattcagaa gacttgaaac
     1321 accactatca gctcttgctg tttcacttcc agaataagga accagagaaa tttttcgggc
     1381 ttattgagga caatctaaag caggttcatc ctctttttca gactgtcttt aaaacctttc
     1441 taaag
//
LOCUS       DBERPV010000072         1301 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.72, whole genome shotgun sequence.
ACCESSION   DBERPV010000072 DBERPV010000000
VERSION     DBERPV010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1301
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.72"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..1021
                     /locus_tag="ACL8C7_002012"
                     /pseudo
     CDS             1..1021
                     /locus_tag="ACL8C7_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            1155..>1301
                     /locus_tag="ACL8C7_002013"
     CDS             1155..>1301
                     /locus_tag="ACL8C7_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HGS1396139.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     ECGNQ"
BASE COUNT          497 a          233 c          239 g          332 t
ORIGIN      
        1 caagagggag agtacctaaa atgggacgta agccaaaaac gagacctgaa gagaggacag
       61 aattagaacg tcttcaatca gaaaatgagt acctgagagc ggagaatgcc atcctaaaaa
      121 agttaagaga actccgattg aaggaggaaa aagagaaaga agaaagacag aaattgttca
      181 agaattaatg actgagtttt cgttagttct tcttctaaaa tccattaaac tagctcgttg
      241 gacctactac tatcacttga aacagctaga caaaacagat aaggaccaag agcttaaagc
      301 tgaaattcaa tccattttta tcgaacacaa gggaaattat gcttatcgcc gggttcattt
      361 agaactaaga aatcgtgctt atctggtaaa tcataaaaga gttcaaggct tgataaaagt
      421 actcaattta caagctaaaa tgcgacagaa acgaaaatat tcttctcata aaggagacgt
      481 tggcaagaag gcagagaatc tcattcaagg ccaatttgaa ggctctaaaa caatggaaaa
      541 gtgctacaca gatgtgacag aatttgccat tccagcaagt actcaaaagc tttacttatc
      601 accagtttta gatggcttta acagcgaaat tatcgcctat aatctttcaa cttcacccaa
      661 tttagaacaa gtacaaacaa tgttggaaca gtcattcaca gagaagcact acgagaatac
      721 gattctccat agtgaccaag gctggcaata tcaacacgat tcttatcatc agtttcttga
      781 gggtaaggga attcaagcat ccatttcacg taagggtaac agcccagaca atggtatgat
      841 ggagtccttt tttgggattc tgaaatcgga aatgttttat ggctatgaga aaacatttaa
      901 atcacttaat cgattggaac aagctattgt agactatatt gattactaca acaataaacg
      961 aattaaggta aaactaaaag gacttagccc tgtgcaatac agaactaaat ccttcggata
     1021 aattaattgt ggttctataa tatttgtagt gggtaaatcc actatagata ttatggagcc
     1081 tattttattg tagaaaaaaa gtcccatatg acctataatg aaaagcgaca aaacaactca
     1141 ttagaaagaa tcatatggaa caattacatt ttatcacaaa attactagac attaaagacc
     1201 ctaatatcca gattttagac atcatcaata aggatacaca caaggaaatc atcgccaaac
     1261 tggactacga cgccccatct tgccctgagt gcggaaatca a
//
LOCUS       DBERPV010000073         1173 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.73, whole genome shotgun sequence.
ACCESSION   DBERPV010000073 DBERPV010000000
VERSION     DBERPV010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1173
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.73"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..144
                     /locus_tag="ACL8C7_002014"
     CDS             <1..144
                     /locus_tag="ACL8C7_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HGS1396140.1"
                     /translation="KERSKVENIFAKVETFKMFSTTYRNHRKRFGLRMNLIAGIINHE
                     LGF"
     gene            complement(882..1142)
                     /locus_tag="ACL8C7_002015"
     CDS             complement(882..1142)
                     /locus_tag="ACL8C7_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1396141.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLVDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNNDISLDQNEIFEILKNFLDG"
BASE COUNT          394 a          217 c          195 g          367 t
ORIGIN      
        1 aaggagagaa gcaaggttga gaacatcttt gccaaagtag aaacgtttaa aatgttttca
       61 acaacctatc gaaatcatcg taaacgcttt ggattacgaa tgaatttgat tgctggtatt
      121 atcaatcatg aactaggatt ctagttttgc aggaagtcta ttatatatgc acagacatat
      181 gaaatctttt tgagatagca gttatgatat atttatccat tcacaacatc ttctgtacca
      241 atactacaat attggtacat tttgattaca caatcgtttc aaaaaatatg atggaagcct
      301 gagtatttta tagtaactcc cttcctatca actagatcaa ccagttgagt gttgaatgtt
      361 gaaacaccct agcctcagca aaggactatg agcagcattt cctagccaat aggacgctcc
      421 aaatcaccta ttctaaatcc atcactagct tggtcagtaa gatacagact gcaaggcaag
      481 actgacgtgg ttgatgagat tttggaagag tattacaatc atagattcac cagtagactt
      541 gaccgcagat ttaactatag tatattgaaa ctagaatagt acacctctgc ttctaaaaca
      601 ttgttagaaa tcgatttgac tgtcctgatc aatttgtcct gttcttgttt catttcacta
      661 tactaaaaaa ccacctgaaa caaatcaagt gactagagga taaaaacaaa gactgggcaa
      721 aaagttttga aaagcaaaaa acgcataata tcaggtcttg aaaaaccttg atactatacg
      781 tttgattgtg ggaagattga cttcattttc tcctgaaatt gaagtttttt ctagtttcca
      841 gatatagacg aattcaatat agccatctcg ctacaattat tttaaccatc gagaaaattt
      901 ttcagaattt caaaaatttc attttgatcc aatgaaatgt cattattttg aagaatagtt
      961 gacttcacag gctctaattc tatcacaaag cggtgcatgt ctgcttttac cgcactactt
     1021 gatgttatag ccgataactt ttcatctact agcaaggaag ctgtcaaacg ggtaaggtca
     1081 ttcaaatgct ttttaatgga cttacttaaa ccttgagcac ctgtggcaga gcgctccctc
     1141 atatccagcc aagctttagc cttaaaaata att
//
LOCUS       DBERPV010000074         1162 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.74, whole genome shotgun sequence.
ACCESSION   DBERPV010000074 DBERPV010000000
VERSION     DBERPV010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1162
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.74"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            74..529
                     /locus_tag="ACL8C7_002016"
     CDS             74..529
                     /locus_tag="ACL8C7_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGS1396142.1"
                     /translation="MQWQTQLSEKKANTDYIARYGVYAVIPNPEQKQIVLVQEPNGAW
                     FLPCGEIEAGENHQEALKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLY
                     EATPFKEVQKPLENFNHIAWFPIDEAIKNLKRGSHKWAIESWKKQHKID"
     gene            694..993
                     /locus_tag="ACL8C7_002017"
     CDS             694..993
                     /locus_tag="ACL8C7_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HGS1396143.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
BASE COUNT          412 a          229 c          195 g          326 t
ORIGIN      
        1 aagattatac cacattgtgt actatttttg gttcatttca ctataataat aacgatacta
       61 gataatgagg aaaatgcaat ggcaaaccca actttcggag aaaaaagcga atacagacta
      121 tattgctcgc tatggcgtat atgcagttat ccctaatcct gaacaaaaac aaattgttct
      181 tgttcaagaa ccaaatggtg cttggttcct accatgtgga gaaattgaag caggtgaaaa
      241 tcatcaggaa gccctaaagc gtgagttgat tgaagagctt ggtttcacag cagaaattgg
      301 tacctattac ggacaagctg acgaatattt ctattctcgt catcgtgata cctactacta
      361 caatcctgcc tacctctatg aagcaactcc tttcaaagaa gtacaaaagc cactagaaaa
      421 ctttaatcat attgcctggt tccctattga cgaggctatc aaaaacctta aacgtggtag
      481 ccataaatgg gccattgaat cttggaaaaa acagcataag attgactaat actcaatgaa
      541 aataaaattc aaaccacgtc agcgtcgcct taccgtactc aagtatagcc tgcggctagc
      601 ttcctagttt gctcttttat tttcattgag tataaatcaa gcgactttat tcaaaaagtg
      661 ctataataga attagaaaat cggaggaaat attatgaagc ttatcaatac gacaaactca
      721 cactcgcaac ttgtaaaaag tcagctagaa agtaccgatg caacccttgt tgaggtttat
      781 tctgcaggga atacagatgt tatttttacc caagctccgc ttcactatga aatcctcatc
      841 tcaaacaaac accgtgctat tcgtgagcct gaaatcgaaa ccattcaaga atttttcttg
      901 aaacgtaaaa ttgataagac ctctgttgat gaagccaata tcaagacact ctactcagag
      961 aaattaattg gaatttcaat cccaatcaag taagaaaatt gagtaaaaac tcgatttgag
     1021 agaaagtcca ataagtcttt ccataataaa acgcatagta gcaagagttt ctacacccac
     1081 tattatgcgt ttttatcatt ttgaaatcta ctgctaatca atgaagaagc aaagatcaaa
     1141 ctaggcagct agttacaagt ta
//
LOCUS       DBERPV010000075         1091 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.75, whole genome shotgun sequence.
ACCESSION   DBERPV010000075 DBERPV010000000
VERSION     DBERPV010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1091
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.75"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(1..229)
                     /locus_tag="ACL8C7_002018"
                     /pseudo
     CDS             complement(1..229)
                     /locus_tag="ACL8C7_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
     gene            complement(475..786)
                     /locus_tag="ACL8C7_002019"
     CDS             complement(475..786)
                     /locus_tag="ACL8C7_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CHY zinc finger protein"
                     /protein_id="HGS1396144.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(801..>1091)
                     /locus_tag="ACL8C7_002020"
     CDS             complement(801..>1091)
                     /locus_tag="ACL8C7_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HGS1396145.1"
                     /translation="VVSYDDAAQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHD
                     AKGNKIDRAPNPMELLTIKVPQPVQSGDMVRALKEGLINFYKEDGTSVTVRA"
BASE COUNT          337 a          214 c          182 g          358 t
ORIGIN      
        1 atacatagtg aatagactcc atacgtcctt cgatttttag actgtccaca ccattttcaa
       61 tcatatctgg aatgtggtca atcatagaca tgtcaacggc tgacattgaa aattcttctg
      121 gaatctcacc ctgcaaactc ttacgttctt tcccaaatgg catatcgtaa aggtcgtact
      181 tccaacggca tgactgagaa catccaccac ggttggcatc acgcatactc tagacggatt
      241 gttttgacaa ttctaatctt ttagactttg cataataact gttaaacagt tgaaaattaa
      301 cccagtttta acaagtagtc aaaataccag ataaaggaaa aaagtcttta aaatcttaaa
      361 aacgcatagt atcaggtatt gaacaatctt gatattatgc gttttattgt gggaagattt
      421 acttcatttt ctcttggaat tgagttttct cctacttcaa aactagatga tttgctattt
      481 aaaatagcgt tccttatgat tttggcaacc tggattaaag cgagaaaaac aaaaggggca
      541 acttaaactt tctttatatt gcttatatgt tagtagtttt agacaaacac cacataaaat
      601 aggcttatcc tgtatcaaag ataagggata cggctcaaaa gggtgatttt ctaatgaatc
      661 atgacaccga taacaagcat aatacttttt acaatcatag cattgtaaag caataatatc
      721 cagcttgcta tggtaatgaa tgcatcttgt ttgcttatcc actaagaaac cctgtgcctc
      781 tatcatttcc ttttcctttc ttaagctcga actgtgacgc tggttccatc ttccttataa
      841 aaattgatga gtccttcttt taatgcacga accatgtctc ctgattgaac gggttgtggg
      901 actttaatag tcaatagttc cattggattt ggagcgcggt cgattttatt tcctttggca
      961 tcatgcaaat cttcaatata ggtttcaaaa tgacggaaac ctggaccata aaactcaact
     1021 tggtcccctt cgttaatgac atttcgttga cgaatagttg ctgtttgtgc cgcatcatca
     1081 taagaaacca c
//
LOCUS       DBERPV010000076          777 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.76, whole genome shotgun sequence.
ACCESSION   DBERPV010000076 DBERPV010000000
VERSION     DBERPV010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 777)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 777)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..777
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.76"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            16..86
                     /locus_tag="ACL8C7_002021"
     tRNA            16..86
                     /locus_tag="ACL8C7_002021"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:48..50,aa:Gly,seq:tcc)
     gene            122..195
                     /locus_tag="ACL8C7_002022"
     tRNA            122..195
                     /locus_tag="ACL8C7_002022"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:156..158,aa:Ile,seq:gat)
     gene            202..289
                     /locus_tag="ACL8C7_002023"
     tRNA            202..289
                     /locus_tag="ACL8C7_002023"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:236..238,aa:Ser,seq:gct)
     gene            complement(496..>777)
                     /locus_tag="ACL8C7_002024"
     CDS             complement(496..>777)
                     /locus_tag="ACL8C7_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS1396146.1"
                     /translation="KEPEKFFGLIEDNLKQVHPIFQTVFKTFLKDKEKIVNALQLHYS
                     NAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
BASE COUNT          203 a          130 c          175 g          269 t
ORIGIN      
        1 attgatagta tttatgcggg tgtagtttag tggtaaaact acagccttcc aagctgttgt
       61 cgcgagttcg attctcgtca cccgctttga actttgttca aattaccaag ttttttaact
      121 tgggcgcgta gctcaggtgg ttagagcgca cgcctgataa gcgtgaggtc ggtggttcga
      181 gtccactcgt gcccattaat tggagaatta ctcaagaggc tgaagaggac ggtttgctaa
      241 atcgttaggt cgggtaactg gcgcaagggt tcgaatccct tattctccgt tttaatgaga
      301 gtttgtaact ctctttttta tttttagaga caataaagct tcagatccgt aaaacttaat
      361 tgaattacta atctgaagtt atttttatgg ctctttgtca actgtagtgg gttgaagaaa
      421 agctaagctc gagaaaggac aaatttcgtc ctttcttttt tggctctttg tcaactgtag
      481 tgggttgaaa aaaagctaag ctcgagaaag gacaaatttt gtcctttctt ttttgatgtt
      541 caaagcgata aaaatccttt ttttgaagtt ttcaaagttc cgaaatccaa aggcgtttcg
      601 tttgataagt ttgatgagat tatttgtcgc ttccagtttg gcgttagaat agtgtagttg
      661 aagggcgttg acaatctttt ctttatcttt gaggaaggtt ttaaagacag tctgaaaaat
      721 aggatgaacc tgcttcagat tgtcctcaat aagcccgaaa aatttctctg gttcctt
//
LOCUS       DBERPV010000077          692 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.77, whole genome shotgun sequence.
ACCESSION   DBERPV010000077 DBERPV010000000
VERSION     DBERPV010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..692
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.77"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(74..147)
                     /locus_tag="ACL8C7_002025"
     tRNA            complement(74..147)
                     /locus_tag="ACL8C7_002025"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(111..113),aa:Arg,seq:acg)
     gene            complement(157..242)
                     /locus_tag="ACL8C7_002026"
     tRNA            complement(157..242)
                     /locus_tag="ACL8C7_002026"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(206..208),aa:Leu,seq:taa)
     gene            complement(250..321)
                     /locus_tag="ACL8C7_002027"
     tRNA            complement(250..321)
                     /locus_tag="ACL8C7_002027"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Gly,seq:gcc)
     gene            complement(344..416)
                     /locus_tag="ACL8C7_002028"
     tRNA            complement(344..416)
                     /locus_tag="ACL8C7_002028"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(381..383),aa:Thr,seq:tgt)
     gene            complement(435..516)
                     /locus_tag="ACL8C7_002029"
     tRNA            complement(435..516)
                     /locus_tag="ACL8C7_002029"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(480..482),aa:Leu,seq:tag)
     gene            complement(522..594)
                     /locus_tag="ACL8C7_002030"
     tRNA            complement(522..594)
                     /locus_tag="ACL8C7_002030"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(559..561),aa:Lys,seq:ttt)
     gene            complement(619..691)
                     /locus_tag="ACL8C7_002031"
     tRNA            complement(619..691)
                     /locus_tag="ACL8C7_002031"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(656..658),aa:Asp,seq:gtc)
BASE COUNT          180 a          205 c          148 g          159 t
ORIGIN      
        1 cgaacctgcg acaccttggt cccaaaccaa gtactctacc aagctgagct acttcccgag
       61 ttaaatagaa aaatgcaccc tagaggagtc gaacctctaa ccgcctgatt cgtagtcagg
      121 tactctatcc agttgagcta agggtgctcc atattatgcc gaggaccgga atcgaaccgg
      181 tacgatcgtt accaatcgca ggattttaag tcctgtgcgt ctgccagttc cgccaccccg
      241 gcctctctaa gcgaacgacg ggattcgaac ccgcgacccc caccttggca aggtagtgtt
      301 ctaccactga actacgttcg cactgttttc ttctatctaa aaatgccggc tacatgactt
      361 gaacacgcga ccctctgatt acaaatcaga tgctctacca actgagctaa gccggctcat
      421 ttgttatatc ttaatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
      481 taaatctggt gcgtctgcca attccgccaa acccgcatat atgacccgta ctgggctcga
      541 accagtgacc cattgattaa aagtcaattg ctctaccaac tgagctaacg agtctaaaat
      601 aacttgcgtt accttaaacg gtcccgacgg gaatcgaacc cgcgatcttc gccgtgacag
      661 ggcgacgtga taaccgctac actacgggac ct
//
LOCUS       DBERPV010000078          642 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.78, whole genome shotgun sequence.
ACCESSION   DBERPV010000078 DBERPV010000000
VERSION     DBERPV010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..642
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.78"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            105..584
                     /locus_tag="ACL8C7_002032"
     CDS             105..584
                     /locus_tag="ACL8C7_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGS1396147.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT          242 a           81 c          149 g          170 t
ORIGIN      
        1 gcctctcttt tttgtgcagt ttaggagcta aagggaacag aatggagaaa atggaacaaa
       61 tgtgttttct aatctgttag actgtatcta gaaaggggaa aattatgatt aaagaattgt
      121 atgaagaagt ccaagggact gtgtataagt gtagaaatga atattacctt catttatggg
      181 aattgtcgga ttgggaccaa gaaggcatgc tctgcttaca tgaattgatt agtagagaag
      241 aaggactggt agacgatatt ccacgtttaa ggaaatattt caaaaccaag tttcgaaatc
      301 gaattttaga ctatatccgt aagcaggaaa gtcagaagcg tagatacgat aaagaaccct
      361 atgaagaagt gggtgagatc agtcatcgta taagtgaggg gggtctctgg ctagatgatt
      421 attatctctt tcatgaaaca ctaagagatt atagaaacaa acaaagtaaa gagaaacaag
      481 aagaactaga acgcgtctta agcaatgaac gatttcgagg gcgtcaaaga gtattaagag
      541 acttacgcat tgtgtttaag gagtttacta tccgtaccca ttagtaagtc atgcaaaaaa
      601 aatgaaaaaa attagaaaaa gtagttgaca aagtttgaaa ag
//
LOCUS       DBERPV010000079          510 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.79, whole genome shotgun sequence.
ACCESSION   DBERPV010000079 DBERPV010000000
VERSION     DBERPV010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..510
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.79"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(259..>510)
                     /locus_tag="ACL8C7_002033"
     CDS             complement(259..>510)
                     /locus_tag="ACL8C7_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGS1396148.1"
                     /translation="VPAQPGTEDKKPSAPKPDMQPSPQPEGKKPSVPEINQEKEKAKL
                     AVATEKKLPSTGVASNLVLEIIGLLGLIGTSFIAMKRRK"
BASE COUNT          144 a          101 c           86 g          179 t
ORIGIN      
        1 ctgaatatca aaaaagaaag gacaaaattt gtcctttctc gagcttagct gacttcaacc
       61 cactacagtt gacaaagagc cttaattgtc taacttttgc ggttcactag ccttctcttt
      121 ttatatctta gattcatctc tatatgaaat gacttataat tattagatac caattataag
      181 taaaatcttt gggatcttca atggttaacc aatcaaatgc taaatatcga aagtggatat
      241 ttttaaaaaa ctgaatcatt attttcttct tttcatcgcg atgaatgaag ttccaatcaa
      301 accaaggaga ccaatgatct caagaactag attagacgcc actcctgtag atggcaattt
      361 cttctctgtt gctacagcaa gcttagcttt ttctttctcc tgattaatct ctggtacact
      421 tggtttctta ccctctggtt gagggcttgg ttgcatatct ggttttggag cagatggctt
      481 tttatcctca gtaccgggtt gtgccggtac
//
LOCUS       DBERPV010000080          458 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.80, whole genome shotgun sequence.
ACCESSION   DBERPV010000080 DBERPV010000000
VERSION     DBERPV010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.80"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..>458
                     /locus_tag="ACL8C7_002034"
     CDS             <1..>458
                     /locus_tag="ACL8C7_002034"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS1396149.1"
                     /translation="PDTWEWVRIKSIYWNFGQNKPEKSFRYIDTSSIDRKKNIINYKN
                     LQYLSPEQAPSRARKLVSQNSVLFSTVRPYLKNIAVVRELKEYLIASTAFIVLDTLLN
                     ETYLKYYLLSDNFINRVNNKSTGTSYPAINDYNFNLLLIALPPLSEQQRI"
BASE COUNT          166 a           71 c           67 g          154 t
ORIGIN      
        1 ttcctgatac ttgggagtgg gtgaggataa aatcaattta ttggaatttt gggcaaaata
       61 agccagagaa atcctttagg tatatagata cgtctagtat tgatagaaaa aagaatataa
      121 tcaactacaa aaatctacaa tatctttcac ctgaacaagc gccttcccgt gctagaaaat
      181 tagtttcgca gaatagtgtc ttattttcaa cagttagacc atatctaaaa aatattgctg
      241 tagttagaga acttaaagag tatttgatag ctagtacagc atttattgtt ttggatactt
      301 tacttaacga aacatatttg aaatattatt tattatcaga taattttatc aatcgtgtta
      361 ataataaatc tactggaaca agttatcctg caatcaatga ttataatttt aatctattat
      421 taattgctct ccccccacta tccgaacaac aacgcata
//
LOCUS       DBERPV010000081          449 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.81, whole genome shotgun sequence.
ACCESSION   DBERPV010000081 DBERPV010000000
VERSION     DBERPV010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.81"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..449
                     /locus_tag="ACL8C7_002035"
                     /pseudo
     CDS             1..449
                     /locus_tag="ACL8C7_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT          132 a           92 c           88 g          137 t
ORIGIN      
        1 ctagaattct ccttagaaag cgtcgaaagc gtcgtttcaa gtgctatcat tgttctaaaa
       61 tgatggtcgc tgaaacttct atcgtcaaga aaaatcacca aattcctcgt attatcaacc
      121 aaaaaattgc gcaaaagttg attgagaaga tttctatgac cgatattgct catcagctgg
      181 ccatttcaac ttcaactgtc attcgaaagc tcaatgattc tcactttgag catgattttt
      241 cgcgtcttcc tgagattatg tcctgggacg ttgaaacagt ccggggagtg actgtttcaa
      301 tcgggagatg gagatgagct ttattgcgca agattttaac aatctcaata tcatcactgt
      361 tcttgaaggt agaacacaag ctgtcatccg agatcacttt cttaaatatg atagagccgt
      421 ccgatgtcgc gtcaaaatca ttactatgg
//
LOCUS       DBERPV010000082          395 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC61 isolate 467290
            SAMN38107443-rid24768823.denovo.82, whole genome shotgun sequence.
ACCESSION   DBERPV010000082 DBERPV010000000
VERSION     DBERPV010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107443
            Sequence Read Archive: SRR26673251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570480.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570480.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 13:57:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,036
            CDSs (total)                      :: 1,996
            Genes (coding)                    :: 1,868
            CDSs (with protein)               :: 1,868
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 57 of 128
            Pseudo Genes (incomplete)         :: 65 of 128
            Pseudo Genes (internal stop)      :: 45 of 128
            Pseudo Genes (multiple problems)  :: 34 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..395
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107443-rid24768823.denovo.82"
                     /strain="GPSC61"
                     /isolate="467290"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..>395
                     /locus_tag="ACL8C7_002036"
     CDS             <1..>395
                     /locus_tag="ACL8C7_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1396150.1"
                     /translation="SNPIDEKLVKEAVRKVGDGYVFEENGVSRYIPAKDLSAETAAGI
                     DSKLAKQESLSHKLGAKKTDLPSSDREFYNKAYDLLARIHQDLLDNKGRQVDFEALDN
                     LLERLKDVSSDKVKLVDDILAFLAPIRHP"
BASE COUNT          128 a           70 c           88 g          109 t
ORIGIN      
        1 caagcaatcc aattgatgag aaattggtca aagaagctgt tcgaaaagta ggcgatggtt
       61 atgtctttga ggagaatgga gtttctcgtt atatcccagc caaggatctt tcagcagaaa
      121 cagcagcagg cattgatagc aaactggcca agcaggaaag tttatctcat aagctaggag
      181 ctaagaaaac tgacctccca tctagtgata gagaatttta caataaggct tatgacttac
      241 tagcaagaat tcaccaagat ttacttgata ataaaggtcg acaagttgat tttgaggctt
      301 tggataacct gttggaacga ctcaaggatg tctcaagtga taaagtcaag ttagtggatg
      361 atattcttgc cttcttagct ccgattcgtc atcca
//
